RU2551963C2
(ru)
*
|
2010-09-09 |
2015-06-10 |
Пфайзер Инк. |
Молекулы, связывающиеся с 4-1вв
|
WO2012145183A2
(en)
*
|
2011-04-19 |
2012-10-26 |
Pfizer Inc. |
Combinations of anti-4-1bb antibodies and adcc-inducing antibodies for the treatment of cancer
|
AU2013268418B2
(en)
|
2012-05-30 |
2017-12-07 |
Chugai Seiyaku Kabushiki Kaisha |
Target-tissue-specific antigen-binding molecule
|
US9834610B2
(en)
*
|
2013-01-31 |
2017-12-05 |
Thomas Jefferson University |
Fusion proteins for modulating regulatory and effector T cells
|
US9944992B2
(en)
|
2013-03-15 |
2018-04-17 |
The University Of Chicago |
Methods and compositions related to T-cell activity
|
EP2982689B1
(en)
|
2013-04-02 |
2020-08-26 |
Chugai Seiyaku Kabushiki Kaisha |
Fc region variant
|
US10781242B2
(en)
|
2013-09-24 |
2020-09-22 |
Medicenna Therapeutics Inc. |
Interleukin-2 fusion proteins and uses thereof
|
US20160264670A1
(en)
*
|
2013-11-06 |
2016-09-15 |
Bristol-Myers Squibb Company |
Immunotherapeutic dosing regimens and combinations thereof
|
WO2015083764A1
(ja)
|
2013-12-04 |
2015-06-11 |
中外製薬株式会社 |
化合物の濃度に応じて抗原結合能の変化する抗原結合分子及びそのライブラリ
|
DK3466949T3
(da)
|
2013-12-24 |
2021-03-15 |
Bristol Myers Squibb Co |
Tricyklisk forbindelse som anticancermidler
|
TW201613635A
(en)
|
2014-02-04 |
2016-04-16 |
Pfizer |
Combination of a PD-1 antagonist and a 4-1BB agonist for treating cancer
|
KR101503341B1
(ko)
|
2014-03-12 |
2015-03-18 |
국립암센터 |
자가암항원 특이적 cd8+ t 세포의 분리 및 증식방법
|
EP3134102B1
(en)
|
2014-04-24 |
2019-07-03 |
The Board of Trustees of The Leland Stanford Junior University |
Superagonists, partial agonists and antagonists of interleukin-2
|
WO2015179236A1
(en)
|
2014-05-21 |
2015-11-26 |
Pfizer Inc. |
Combination of an anti-ccr4 antibody and a 4-1bb agonist for treating cancer
|
WO2015188085A1
(en)
|
2014-06-06 |
2015-12-10 |
Flexus Biosciences, Inc. |
Immunoregulatory agents
|
HUE047385T2
(hu)
|
2014-06-06 |
2020-04-28 |
Bristol Myers Squibb Co |
Antitestek glükokortikoid indukált tumornekrózis faktor receptor (GITR) ellen és annak felhasználásai
|
WO2016032927A1
(en)
|
2014-08-25 |
2016-03-03 |
Pfizer Inc. |
Combination of a pd-1 antagonist and an alk inhibitor for treating cancer
|
CA2964276A1
(en)
|
2014-11-05 |
2016-05-12 |
Flexus Biosciences, Inc. |
Immunoregulatory agents
|
UY36390A
(es)
|
2014-11-05 |
2016-06-01 |
Flexus Biosciences Inc |
Compuestos moduladores de la enzima indolamina 2,3-dioxigenasa (ido), sus métodos de síntesis y composiciones farmacéuticas que los contienen
|
AR102537A1
(es)
|
2014-11-05 |
2017-03-08 |
Flexus Biosciences Inc |
Agentes inmunomoduladores
|
TWI758928B
(zh)
|
2014-11-21 |
2022-03-21 |
美商必治妥美雅史谷比公司 |
抗cd73抗體及其用途
|
AR103232A1
(es)
|
2014-12-22 |
2017-04-26 |
Bristol Myers Squibb Co |
ANTAGONISTAS DE TGFbR
|
IL308212A
(en)
|
2015-01-20 |
2024-01-01 |
Igm Biosciences Inc |
Tumor necrosis factor-α receptor binding molecules and their uses
|
US10983128B2
(en)
|
2015-02-05 |
2021-04-20 |
Bristol-Myers Squibb Company |
CXCL11 and SMICA as predictive biomarkers for efficacy of anti-CTLA4 immunotherapy
|
CA2977257A1
(en)
*
|
2015-02-22 |
2016-08-25 |
Sorrento Therapeutics, Inc. |
Antibody therapeutics that bind cd137
|
CN112263677A
(zh)
|
2015-02-26 |
2021-01-26 |
默克专利股份公司 |
用于治疗癌症的pd-1/pd-l1抑制剂
|
EP3265454B1
(en)
|
2015-03-02 |
2020-02-26 |
Rigel Pharmaceuticals, Inc. |
Tgf-beta inhibitors
|
CN114751989A
(zh)
*
|
2015-03-31 |
2022-07-15 |
豪夫迈·罗氏有限公司 |
包含三聚体tnf家族配体的抗原结合分子
|
JP2018516238A
(ja)
|
2015-04-03 |
2018-06-21 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
癌の治療のためのインドールアミン−2,3−ジオキシゲナーゼの阻害剤およびそれらの使用方法
|
WO2016162505A1
(en)
|
2015-04-08 |
2016-10-13 |
F-Star Biotechnology Limited |
Her2 binding agent therapies
|
HUE053903T2
(hu)
|
2015-04-13 |
2021-07-28 |
Five Prime Therapeutics Inc |
Kombinációs terápia rák ellen
|
EP3294736B1
(en)
|
2015-05-11 |
2020-07-22 |
Bristol-Myers Squibb Company |
Tricyclic compounds as anticancer agents
|
US10174024B2
(en)
|
2015-05-12 |
2019-01-08 |
Bristol-Myers Squibb Company |
5H-pyrido[3,2-B]indole compounds as anticancer agents
|
US9725449B2
(en)
|
2015-05-12 |
2017-08-08 |
Bristol-Myers Squibb Company |
Tricyclic compounds as anticancer agents
|
ES2938525T3
(es)
*
|
2015-05-18 |
2023-04-12 |
Pieris Pharmaceuticals Gmbh |
Polipéptido de fusión anticanceroso
|
RU2017142008A
(ru)
|
2015-05-21 |
2019-06-24 |
Эллигейтор Биосайенс Аб |
Новые полипептиды
|
GB201509338D0
(en)
*
|
2015-05-29 |
2015-07-15 |
Bergenbio As |
Combination therapy
|
WO2016196228A1
(en)
|
2015-05-29 |
2016-12-08 |
Bristol-Myers Squibb Company |
Antibodies against ox40 and uses thereof
|
US10869924B2
(en)
|
2015-06-16 |
2020-12-22 |
Merck Patent Gmbh |
PD-L1 antagonist combination treatments
|
KR20210089270A
(ko)
|
2015-07-16 |
2021-07-15 |
바이오카인 테라퓨틱스 리미티드 |
암 치료용 조성물 및 방법
|
US10399987B2
(en)
|
2015-07-28 |
2019-09-03 |
Bristol-Myer Squibb Company |
TGF beta receptor antagonists
|
US20180230431A1
(en)
|
2015-08-07 |
2018-08-16 |
Glaxosmithkline Intellectual Property Development Limited |
Combination Therapy
|
EP3341372A1
(en)
|
2015-08-25 |
2018-07-04 |
Bristol-Myers Squibb Company |
Tgf beta receptor antagonists
|
CN108026169B
(zh)
*
|
2015-09-22 |
2021-05-28 |
苏州丁孚靶点生物技术有限公司 |
抗人cd137的完全人抗体及其应用
|
US10149887B2
(en)
|
2015-10-23 |
2018-12-11 |
Canbas Co., Ltd. |
Peptides and peptidomimetics in combination with t cell activating and/or checkpoint inhibiting agents for cancer treatment
|
US10273281B2
(en)
|
2015-11-02 |
2019-04-30 |
Five Prime Therapeutics, Inc. |
CD80 extracellular domain polypeptides and their use in cancer treatment
|
BR112018008891A8
(pt)
|
2015-11-03 |
2019-02-26 |
Janssen Biotech Inc |
anticorpos que se ligam especificamente a pd-1 e tim-3 e seus usos
|
GB201519481D0
(en)
|
2015-11-04 |
2015-12-16 |
Cancer Rec Tech Ltd |
Immunomodulatory antibodies
|
WO2017087678A2
(en)
|
2015-11-19 |
2017-05-26 |
Bristol-Myers Squibb Company |
Antibodies against glucocorticoid-induced tumor necrosis factor receptor (gitr) and uses thereof
|
WO2017091580A1
(en)
|
2015-11-23 |
2017-06-01 |
Five Prime Therapeutics, Inc. |
Predicting response to cancer treatment with fgfr2 inhibitors
|
KR20180094036A
(ko)
|
2015-12-15 |
2018-08-22 |
브리스톨-마이어스 스큅 컴퍼니 |
Cxcr4 수용체 길항제
|
SG11201805532XA
(en)
|
2016-01-11 |
2018-07-30 |
Inhibrx Inc |
Multivalent and multispecific 41bb-binding fusion proteins
|
EP3408294A1
(en)
|
2016-01-25 |
2018-12-05 |
Pfizer Inc. |
Combination of an ox40 agonist and a 4-1bb agonist monoclonal antibody for treating cancer
|
SG10201913033UA
(en)
|
2016-03-04 |
2020-03-30 |
Bristol Myers Squibb Co |
Combination therapy with anti-cd73 antibodies
|
WO2017184619A2
(en)
|
2016-04-18 |
2017-10-26 |
Celldex Therapeutics, Inc. |
Agonistic antibodies that bind human cd40 and uses thereof
|
JP2019519485A
(ja)
|
2016-05-04 |
2019-07-11 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
インドールアミン2,3−ジオキシゲナーゼ阻害剤およびその使用方法
|
CN109414421A
(zh)
|
2016-05-04 |
2019-03-01 |
百时美施贵宝公司 |
吲哚胺2,3-双加氧酶的抑制剂及其使用方法
|
CN109348714A
(zh)
|
2016-05-04 |
2019-02-15 |
百时美施贵宝公司 |
吲哚胺2,3-双加氧酶的抑制剂及其使用方法
|
KR20190004742A
(ko)
|
2016-05-04 |
2019-01-14 |
브리스톨-마이어스 스큅 컴퍼니 |
인돌아민 2,3-디옥시게나제의 억제제 및 그의 사용 방법
|
KR20190004743A
(ko)
|
2016-05-04 |
2019-01-14 |
브리스톨-마이어스 스큅 컴퍼니 |
인돌아민 2,3-디옥시게나제의 억제제 및 그의 사용 방법
|
US10875921B2
(en)
|
2016-05-27 |
2020-12-29 |
Abbvie Biotherapeutics Inc. |
Anti-4-1BB antibodies and their uses
|
PE20190562A1
(es)
|
2016-05-27 |
2019-04-22 |
Abbvie Biotherapeutics Inc |
Proteinas de union biespecificas que se unen a una proteina inmunomoduladora y un antigeno tumoral
|
MX2018015684A
(es)
|
2016-06-17 |
2019-08-29 |
Magenta Therapeutics Inc |
Composiciones y metodos para el agotamiento de celulas cd117.
|
RU2756236C2
(ru)
|
2016-06-20 |
2021-09-28 |
Кимаб Лимитед |
PD-L1 специфические антитела
|
KR20240017129A
(ko)
|
2016-07-14 |
2024-02-06 |
젠맵 에이/에스 |
Cd40 및 cd137에 대한 다중특이적 항체
|
PE20190418A1
(es)
|
2016-07-14 |
2019-03-19 |
Bristol Myers Squibb Co |
Anticuerpos contra proteina 3 que contiene el dominio de mucina e inmunoglobulina de linfocitos t (tim3) y sus usos
|
GB201612520D0
(en)
|
2016-07-19 |
2016-08-31 |
F-Star Beta Ltd |
Binding molecules
|
US20190292179A1
(en)
|
2016-07-21 |
2019-09-26 |
Bristol-Myers Squibb Company |
TGF Beta RECEPTOR ANTAGONISTS
|
EP3497126A4
(en)
|
2016-08-12 |
2020-04-08 |
Janssen Biotech, Inc. |
ANTIBODIES OF FC MODIFIED ANTI-TNFR SUPERFAMILY HAVING IMPROVED AGONIST ACTIVITY AND METHODS OF USE THEREOF
|
KR102587941B1
(ko)
|
2016-08-12 |
2023-10-11 |
얀센 바이오테크 인코포레이티드 |
향상된 효능작용 및 이펙터 기능을 갖는 조작된 항체 및 다른 Fc-도메인 함유 분자
|
WO2018035046A1
(en)
|
2016-08-15 |
2018-02-22 |
President And Fellows Of Harvard College |
Treating infections using idsd from proteus mirabilis
|
CN110088132B
(zh)
|
2016-08-17 |
2020-10-27 |
康姆普根有限公司 |
抗tigit抗体,抗pvrig抗体及其组合
|
CN106244611B
(zh)
*
|
2016-08-23 |
2019-05-17 |
浙江普康生物技术股份有限公司 |
一种细胞免疫佐剂tsa-41的制备方法及应用
|
EP3503916A1
(en)
|
2016-08-26 |
2019-07-03 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
EA201990578A1
(ru)
|
2016-09-23 |
2019-10-31 |
|
Связывающие молекулы, которые модулируют биологическую активность, проявляемую клеткой
|
AU2017339856A1
(en)
|
2016-10-06 |
2019-05-23 |
Merck Patent Gmbh |
Dosing regimen of avelumab for the treatment of cancer
|
TWI788307B
(zh)
|
2016-10-31 |
2023-01-01 |
美商艾歐凡斯生物治療公司 |
用於擴增腫瘤浸潤性淋巴細胞之工程化人造抗原呈現細胞
|
US10660909B2
(en)
|
2016-11-17 |
2020-05-26 |
Syntrix Biosystems Inc. |
Method for treating cancer using chemokine antagonists
|
CN108367075B
(zh)
*
|
2016-11-23 |
2022-08-09 |
免疫方舟医药技术股份有限公司 |
4-1bb结合蛋白及其用途
|
US11512134B2
(en)
|
2017-08-01 |
2022-11-29 |
Eli Lilly And Company |
Anti-CD137 antibodies
|
WO2018132279A1
(en)
|
2017-01-05 |
2018-07-19 |
Bristol-Myers Squibb Company |
Tgf beta receptor antagonists
|
TW201837168A
(zh)
|
2017-01-06 |
2018-10-16 |
美商艾歐凡斯生物治療公司 |
以腫瘤壞死因子受體超家族(tnfrsf)促效劑使腫瘤浸潤淋巴球(til)擴增及til與tnfrsf促效劑的治療組合
|
SG10201914064QA
(en)
*
|
2017-01-06 |
2020-03-30 |
Eutilex Co Ltd |
Anti-human 4-1 bb antibodies and use thereof
|
WO2018186924A1
(en)
|
2017-01-17 |
2018-10-11 |
The University Of Chicago |
Dysfunctional antigen-specific cd8+ t cells in the tumor microenvironment
|
WO2018134787A2
(en)
|
2017-01-20 |
2018-07-26 |
Magenta Therapeutics, Inc. |
Compositions and methods for the depletion of cd137+ cells
|
US10399962B2
(en)
|
2017-01-20 |
2019-09-03 |
Arcus Biosciences, Inc. |
Azolopyrimidine for the treatment of cancer-related disorders
|
BR112019015900A2
(pt)
|
2017-02-10 |
2020-04-07 |
Genmab B.V. |
polipeptídeo, métodos para aumentar a atividade agonística de um polipeptídeo, para aumentar a atividade de cdc de um polipeptídeo e de tratamento de um indivíduo tendo uma doença, composição, kit de partes, e, uso de um polipeptídeo ou uma composição
|
US11459394B2
(en)
|
2017-02-24 |
2022-10-04 |
Macrogenics, Inc. |
Bispecific binding molecules that are capable of binding CD137 and tumor antigens, and uses thereof
|
CN110709420A
(zh)
|
2017-03-31 |
2020-01-17 |
戊瑞治疗有限公司 |
使用抗gitr抗体的癌症组合疗法
|
BR112019017241A2
(pt)
|
2017-04-13 |
2020-04-14 |
Agenus Inc |
anticorpos anti-cd137 e métodos de uso dos mesmos
|
CA3059939A1
(en)
|
2017-04-21 |
2018-10-25 |
Kyn Therapeutics |
Indole ahr inhibitors and uses thereof
|
KR20190139216A
(ko)
*
|
2017-04-28 |
2019-12-17 |
파이브 프라임 테라퓨틱스, 인크. |
Cd80 세포외 도메인 폴리펩티드를 이용한 치료 방법
|
US11066392B2
(en)
|
2017-05-12 |
2021-07-20 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
WO2018213377A1
(en)
|
2017-05-17 |
2018-11-22 |
Arcus Biosciences, Inc. |
Quinazoline-pyrazole derivatives for the treatment of cancer-related disorders
|
EP3630180A1
(en)
|
2017-06-01 |
2020-04-08 |
Compugen Ltd. |
Triple combination antibody therapies
|
TW201919662A
(zh)
|
2017-06-05 |
2019-06-01 |
美商艾歐凡斯生物治療公司 |
對雙重難治性黑色素瘤使用腫瘤浸潤性淋巴細胞之方法
|
BR112019024291A2
(pt)
|
2017-06-09 |
2020-07-28 |
Providence Health & Services-Oregon |
utilização de cd39 e de cd103 para a identificação de células t tumorais humanas reativas para o tratamento do câncer
|
US11542312B2
(en)
|
2017-06-19 |
2023-01-03 |
Medicenna Therapeutics, Inc. |
IL-2 superagonists in combination with anti-PD-1 antibodies
|
CN116925227A
(zh)
*
|
2017-06-25 |
2023-10-24 |
西雅图免疫公司 |
抗ror1抗体及其制备和使用方法
|
WO2019006283A1
(en)
|
2017-06-30 |
2019-01-03 |
Bristol-Myers Squibb Company |
AMORPHOUS AND CRYSTALLINE FORMS OF IDO INHIBITORS
|
SG10201913144TA
(en)
|
2017-07-11 |
2020-03-30 |
Compass Therapeutics Llc |
Agonist antibodies that bind human cd137 and uses thereof
|
WO2019016402A1
(en)
|
2017-07-20 |
2019-01-24 |
Aptevo Research And Development Llc |
BINDING PROTEINS BINDING AT 5T4 AND 4-1BB, COMPOSITIONS AND METHODS RELATED THERETO
|
KR20200032180A
(ko)
|
2017-07-28 |
2020-03-25 |
브리스톨-마이어스 스큅 컴퍼니 |
항암제로서의 시클릭 디뉴클레오티드
|
BR112020001441A2
(pt)
*
|
2017-08-01 |
2020-08-04 |
Eli Lilly And Company |
anticorpos anti-cd137
|
AU2018319016B2
(en)
|
2017-08-17 |
2023-08-31 |
Ikena Oncology, Inc. |
AHR inhibitors and uses thereof
|
WO2019036855A1
(en)
|
2017-08-21 |
2019-02-28 |
Adagene Inc. |
ANTI-CD137 MOLECULES AND THEIR USE
|
EP3676279B1
(en)
|
2017-08-31 |
2021-12-01 |
Bristol-Myers Squibb Company |
Cyclic dinucleotides as anticancer agents
|
ES2945140T3
(es)
|
2017-08-31 |
2023-06-28 |
Bristol Myers Squibb Co |
Dinucleótidos cíclicos como agentes anticancerosos
|
US11667663B2
(en)
|
2017-08-31 |
2023-06-06 |
Bristol-Myers Squibb Company |
Cyclic dinucleotides as anticancer agents
|
EP3684366A4
(en)
|
2017-09-22 |
2021-09-08 |
Kymera Therapeutics, Inc. |
CRBN LIGANDS AND USES OF THE LATEST
|
IL273432B
(en)
|
2017-09-22 |
2022-09-01 |
Kymera Therapeutics Inc |
Protein compounds and their uses
|
US11203592B2
(en)
|
2017-10-09 |
2021-12-21 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
US11649212B2
(en)
|
2017-10-09 |
2023-05-16 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
MA50352A
(fr)
|
2017-10-10 |
2020-08-19 |
Numab Therapeutics AG |
Anticorps multispécifiques
|
EP3470428A1
(en)
|
2017-10-10 |
2019-04-17 |
Numab Innovation AG |
Antibodies targeting cd137 and methods of use thereof
|
CN111183159A
(zh)
*
|
2017-10-10 |
2020-05-19 |
努玛治疗有限公司 |
靶向cd137的抗体及其使用方法
|
KR20200061399A
(ko)
|
2017-10-10 |
2020-06-02 |
브리스톨-마이어스 스큅 컴퍼니 |
항암제로서의 시클릭 디뉴클레오티드
|
WO2019075090A1
(en)
|
2017-10-10 |
2019-04-18 |
Tilos Therapeutics, Inc. |
ANTI-LAP ANTIBODIES AND USES THEREOF
|
EP3470426A1
(en)
|
2017-10-10 |
2019-04-17 |
Numab Therapeutics AG |
Multispecific antibody
|
CN109651507B
(zh)
*
|
2017-10-12 |
2021-11-26 |
瑞阳(苏州)生物科技有限公司 |
一种激动型4-1bb单克隆抗体
|
US11427610B2
(en)
|
2017-10-16 |
2022-08-30 |
Bristol-Myers Squibb Company |
Cyclic dinucleotides as anticancer agents
|
WO2019089753A2
(en)
*
|
2017-10-31 |
2019-05-09 |
Compass Therapeutics Llc |
Cd137 antibodies and pd-1 antagonists and uses thereof
|
CN111542544A
(zh)
|
2017-11-01 |
2020-08-14 |
百时美施贵宝公司 |
用于治疗癌症的免疫刺激性激动性抗体
|
ES2925450T3
(es)
|
2017-11-06 |
2022-10-18 |
Bristol Myers Squibb Co |
Compuestos de isofuranona útiles como inhibidores de HPK1
|
KR20200086312A
(ko)
|
2017-11-08 |
2020-07-16 |
야페이 상하이 바이오로그 메디신 사이언스 앤드 테크놀로지 컴퍼니 리미티드 |
생체분자의 컨쥬게이트 및 이의 용도
|
TWI701259B
(zh)
|
2017-11-09 |
2020-08-11 |
大陸商上海懷越生物科技有限公司 |
4﹘1bb抗體及其製備方法和應用
|
AU2018368786A1
(en)
|
2017-11-17 |
2020-06-18 |
Iovance Biotherapeutics, Inc. |
TIL expansion from fine needle aspirates and small biopsies
|
EP3713961A2
(en)
|
2017-11-20 |
2020-09-30 |
Compass Therapeutics LLC |
Cd137 antibodies and tumor antigen-targeting antibodies and uses thereof
|
WO2019109238A1
(en)
*
|
2017-12-05 |
2019-06-13 |
Lyvgen Biopharma Co., Ltd. |
Anti-cd137 antibodies and uses thereof
|
SG11202005912PA
(en)
|
2017-12-26 |
2020-07-29 |
Kymera Therapeutics Inc |
Irak degraders and uses thereof
|
CN110003332B
(zh)
*
|
2018-01-05 |
2021-05-11 |
上海原能细胞医学技术有限公司 |
Cd137抗体及其应用
|
US11447449B2
(en)
|
2018-01-05 |
2022-09-20 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
WO2019136456A1
(en)
|
2018-01-08 |
2019-07-11 |
Iovance Biotherapeutics, Inc. |
Processes for generating til products enriched for tumor antigen-specific t-cells
|
US11713446B2
(en)
|
2018-01-08 |
2023-08-01 |
Iovance Biotherapeutics, Inc. |
Processes for generating TIL products enriched for tumor antigen-specific T-cells
|
WO2019136459A1
(en)
|
2018-01-08 |
2019-07-11 |
Iovance Biotherapeutics, Inc. |
Processes for generating til products enriched for tumor antigen-specific t-cells
|
WO2019140387A1
(en)
|
2018-01-12 |
2019-07-18 |
Kymera Therapeutics, Inc. |
Crbn ligands and uses thereof
|
US11485743B2
(en)
|
2018-01-12 |
2022-11-01 |
Kymera Therapeutics, Inc. |
Protein degraders and uses thereof
|
EP3737700A1
(en)
|
2018-01-12 |
2020-11-18 |
Bristol-Myers Squibb Company |
Antibodies against tim3 and uses thereof
|
KR20200110356A
(ko)
*
|
2018-01-15 |
2020-09-23 |
화이자 인코포레이티드 |
키메라 항원 수용체 면역요법을 4-1bb 효능제와 조합하여 투여하는 방법
|
CN111065652A
(zh)
*
|
2018-01-22 |
2020-04-24 |
江苏恒瑞医药股份有限公司 |
抗4-1bb抗体、其抗原结合片段及其医药用途
|
TWI816742B
(zh)
|
2018-01-29 |
2023-10-01 |
美商維泰克斯製藥公司 |
Gcn2抑制劑及其用途
|
CN111867581B
(zh)
|
2018-01-29 |
2023-12-26 |
默克专利股份有限公司 |
Gcn2抑制剂及其用途
|
WO2019148445A1
(en)
|
2018-02-02 |
2019-08-08 |
Adagene Inc. |
Precision/context-dependent activatable antibodies, and methods of making and using the same
|
US10519187B2
(en)
|
2018-02-13 |
2019-12-31 |
Bristol-Myers Squibb Company |
Cyclic dinucleotides as anticancer agents
|
US20210137930A1
(en)
|
2018-02-13 |
2021-05-13 |
Iovance Biotherapeutics, Inc. |
Expansion of tumor infiltrating lymphocytes (tils) with adenosine a2a receptor antagonists and therapeutic combinations of tils and adenosine a2a receptor antagonists
|
WO2019165315A1
(en)
|
2018-02-23 |
2019-08-29 |
Syntrix Biosystems Inc. |
Method for treating cancer using chemokine antagonists alone or in combination
|
US11945834B2
(en)
|
2018-03-08 |
2024-04-02 |
Bristol-Myers Squibb Company |
Cyclic dinucleotides as anticancer agents
|
WO2019173798A1
(en)
|
2018-03-08 |
2019-09-12 |
Rubius Therapeutics, Inc. |
Therapeutic cell systems and methods for treating cancer and infectious diseases
|
JP2021518133A
(ja)
|
2018-03-21 |
2021-08-02 |
ファイブ プライム セラピューティクス, インコーポレイテッド |
酸性pHでVISTAに結合する抗体
|
MA52075A
(fr)
*
|
2018-03-23 |
2021-01-27 |
Lilly Co Eli |
Anticorps anti-cd137 pour une combinaison avec des anticorps anti-pd-l1
|
WO2019182879A1
(en)
|
2018-03-23 |
2019-09-26 |
Eli Lilly And Company |
Anti-cd137 antibodies for combination with anti-pd-1 antibodies
|
AU2018415814A1
(en)
|
2018-03-29 |
2020-10-22 |
Iovance Biotherapeutics, Inc. |
Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy
|
US20210230287A1
(en)
*
|
2018-04-10 |
2021-07-29 |
Wuxi Biologics (Shanghai) Co., Ltd. |
A monoclonal antibody against human 4-1bb, method for preparing the same, and use thereof
|
MX2020010604A
(es)
|
2018-04-12 |
2020-10-20 |
Bristol Myers Squibb Co |
Terapia de combinacion anticancer con anticuerpo antagonista del grupo de diferenciacion 73 (cd73) y anticuerpo antagonista del eje proteina de muerte programada 1 (pd-1)/ligando de muerte programada 1 (pd-l1).
|
AR114284A1
(es)
|
2018-04-13 |
2020-08-12 |
Hoffmann La Roche |
Moléculas de unión a antígeno dirigidas a her2 que comprenden 4-1bbl
|
AU2019255196A1
(en)
|
2018-04-16 |
2020-11-12 |
Arrys Therapeutics, Inc. |
EP4 inhibitors and use thereof
|
CN112368003A
(zh)
|
2018-04-27 |
2021-02-12 |
艾欧凡斯生物治疗公司 |
肿瘤浸润淋巴细胞的基因编辑及其在免疫治疗中的用途
|
US20230339891A1
(en)
|
2018-05-03 |
2023-10-26 |
Bristol-Myers Squibb Company |
Uracil derivatives as mer-axl inhibitors
|
WO2019217753A1
(en)
|
2018-05-10 |
2019-11-14 |
Iovance Biotherapeutics, Inc. |
Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy
|
CA3103629A1
(en)
|
2018-06-15 |
2019-12-19 |
Flagship Pioneering Innovations V, Inc. |
Increasing immune activity through modulation of postcellular signaling factors
|
US11180531B2
(en)
|
2018-06-22 |
2021-11-23 |
Bicycletx Limited |
Bicyclic peptide ligands specific for Nectin-4
|
SI3814348T1
(sl)
|
2018-06-27 |
2023-10-30 |
Bristol-Myers Squibb Company |
Substituirane naftiridinonske spojine, uporabne kot aktivatorji t celic
|
EP3814347B1
(en)
|
2018-06-27 |
2023-05-03 |
Bristol-Myers Squibb Company |
Naphthyridinone compounds useful as t cell activators
|
WO2020010177A1
(en)
|
2018-07-06 |
2020-01-09 |
Kymera Therapeutics, Inc. |
Tricyclic crbn ligands and uses thereof
|
MX2021000009A
(es)
|
2018-07-09 |
2021-03-09 |
Five Prime Therapeutics Inc |
Anticuerpos de union a transcripcion tipo inmunoglobulina 4 (ilt4).
|
US20220073617A1
(en)
|
2018-07-11 |
2022-03-10 |
Five Prime Therapeutics, Inc. |
Antibodies Binding to Vista at Acidic pH
|
SG11202100172XA
(en)
|
2018-07-12 |
2021-02-25 |
F Star Beta Ltd |
Antibody molecules that bind cd137 and ox40
|
BR112021000394A2
(pt)
|
2018-07-12 |
2021-04-06 |
F-Star Beta Limited |
Moléculas de anticorpo que se ligam a pd-l1 e cd137
|
GB201811408D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Beta Ltd |
CD137 Binding Molecules
|
GB201811404D0
(en)
|
2018-07-12 |
2018-08-29 |
F Star Beta Ltd |
Anti-CD137 Antibodies
|
CN112334488B
(zh)
|
2018-07-19 |
2023-12-08 |
伊莱利利公司 |
靶向免疫检查点的双特异性抗体
|
US20210299126A1
(en)
|
2018-07-23 |
2021-09-30 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
US20210355113A1
(en)
|
2018-07-23 |
2021-11-18 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
AU2019312296A1
(en)
|
2018-07-27 |
2021-03-18 |
Arcus Biosciences, Inc. |
Pyridone A2R antagonists
|
AU2019318031A1
(en)
|
2018-08-10 |
2021-02-25 |
Chugai Seiyaku Kabushiki Kaisha |
Anti-CD137 antigen-binding molecule and utilization thereof
|
US10959986B2
(en)
|
2018-08-29 |
2021-03-30 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
US11253525B2
(en)
|
2018-08-29 |
2022-02-22 |
Bristol-Myers Squibb Company |
Inhibitors of indoleamine 2,3-dioxygenase and methods of their use
|
TW202031273A
(zh)
|
2018-08-31 |
2020-09-01 |
美商艾歐凡斯生物治療公司 |
抗pd-1抗體難治療性之非小細胞肺癌(nsclc)病患的治療
|
EP3846793B1
(en)
|
2018-09-07 |
2024-01-24 |
PIC Therapeutics, Inc. |
Eif4e inhibitors and uses thereof
|
TW202028457A
(zh)
|
2018-09-20 |
2020-08-01 |
美商艾歐凡斯生物治療公司 |
來自經冷凍保存之腫瘤樣本之腫瘤浸潤性淋巴細胞(til)之擴增
|
EP3636320A1
(en)
|
2018-10-09 |
2020-04-15 |
Numab Therapeutics AG |
Antibodies targeting cd137 and methods of use thereof
|
JP2022512628A
(ja)
|
2018-10-09 |
2022-02-07 |
ヌマブ セラピューティクス アクチェンゲゼルシャフト |
Cd137を標的とする抗体およびその使用方法
|
CN113164780A
(zh)
|
2018-10-10 |
2021-07-23 |
泰洛斯治疗公司 |
抗lap抗体变体及其用途
|
JP7453219B2
(ja)
|
2018-10-11 |
2024-03-19 |
インヒブリックス, インコーポレイテッド |
Pd-1単一ドメイン抗体およびその治療用組成物
|
TW202039830A
(zh)
|
2018-11-05 |
2020-11-01 |
美商艾歐凡斯生物治療公司 |
用於製造腫瘤浸潤性淋巴細胞之方法及其在免疫療法中之用途
|
AU2019377422A1
(en)
|
2018-11-05 |
2021-05-27 |
Iovance Biotherapeutics, Inc. |
Treatment of NSCLC patients refractory for anti-PD-1 antibody
|
US20220033775A1
(en)
|
2018-11-05 |
2022-02-03 |
Iovance Biotherapeutics, Inc. |
Expansion of tils utilizing akt pathways inhibitors
|
US20230039976A1
(en)
|
2018-11-05 |
2023-02-09 |
Iovance Biotherapeutics, Inc. |
Selection of improved tumor reactive t-cells
|
WO2020107715A1
(en)
*
|
2018-11-30 |
2020-06-04 |
Abl Bio Inc. |
Anti-pd-l1/anti-4-1bb bispecific antibodies and uses thereof
|
US11352350B2
(en)
|
2018-11-30 |
2022-06-07 |
Kymera Therapeutics, Inc. |
IRAK degraders and uses thereof
|
WO2020131547A1
(en)
|
2018-12-19 |
2020-06-25 |
Iovance Biotherapeutics, Inc. |
Methods of expanding tumor infiltrating lymphocytes using engineered cytokine receptor pairs and uses thereof
|
EP3670659A1
(en)
|
2018-12-20 |
2020-06-24 |
Abivax |
Biomarkers, and uses in treatment of viral infections, inflammations, or cancer
|
US20220370606A1
(en)
|
2018-12-21 |
2022-11-24 |
Pfizer Inc. |
Combination Treatments Of Cancer Comprising A TLR Agonist
|
SG11202106353VA
(en)
|
2019-02-26 |
2021-07-29 |
Pieris Pharmaceuticals Gmbh |
Novel fusion proteins specific for cd137 and gpc3
|
AU2020242284A1
(en)
|
2019-03-19 |
2021-09-16 |
Fundació Privada Institut D'investigació Oncològica De Vall Hebron |
Combination therapy for the treatment of cancer
|
KR20220002336A
(ko)
|
2019-03-29 |
2022-01-06 |
미스트 쎄라퓨틱스, 엘엘씨 |
T 세포 치료제를 제조하기 위한 생체외 방법 및 관련 조성물 및 방법
|
AU2020253990A1
(en)
|
2019-04-02 |
2021-10-28 |
Bicycletx Limited |
Bicycle toxin conjugates and uses thereof
|
MA55565A
(fr)
|
2019-04-05 |
2022-02-09 |
Kymera Therapeutics Inc |
Agents de dégradation de stat et leurs utilisations
|
JP2022530026A
(ja)
|
2019-04-24 |
2022-06-27 |
ハイデルベルク ファルマ リサーチ ゲゼルシャフト ミット ベシュレンクテル ハフツング |
アマトキシン抗体薬物複合体及びその使用
|
EP3962493A2
(en)
|
2019-05-03 |
2022-03-09 |
Flagship Pioneering Innovations V, Inc. |
Methods of modulating immune activity/level of irf or sting or of treating cancer, comprising the administration of a sting modulator and/or purinergic receptor modulator or postcellular signaling factor
|
KR20220008306A
(ko)
|
2019-05-10 |
2022-01-20 |
리브젠 바이오파마 코., 엘티디. |
인간화 항-cd137 항체 및 이의 용도
|
US20230242478A1
(en)
|
2019-05-13 |
2023-08-03 |
Bristol-Myers Squibb Company |
AGONISTS OF ROR GAMMAt
|
WO2020231766A1
(en)
|
2019-05-13 |
2020-11-19 |
Bristol-Myers Squibb Company |
AGONISTS OF ROR GAMMAt
|
US20220249559A1
(en)
|
2019-05-13 |
2022-08-11 |
Iovance Biotherapeutics, Inc. |
Methods and compositions for selecting tumor infiltrating lymphocytes and uses of the same in immunotherapy
|
US20220241412A1
(en)
|
2019-05-24 |
2022-08-04 |
Pfizer Inc. |
Combination therapies using cdk inhibitors
|
US20230053328A9
(en)
|
2019-05-24 |
2023-02-16 |
Pfizer Inc. |
Combination therapies using cdk inhibitors
|
CN114502540A
(zh)
|
2019-05-31 |
2022-05-13 |
医肯纳肿瘤学公司 |
Tead抑制剂和其用途
|
TW202112804A
(zh)
|
2019-06-04 |
2021-04-01 |
瑞士商分子夥伴股份有限公司 |
多特異性蛋白質
|
US20220306630A1
(en)
|
2019-08-06 |
2022-09-29 |
Bristol-Myers Squibb Company |
AGONISTS OF ROR GAMMAt
|
AR119821A1
(es)
|
2019-08-28 |
2022-01-12 |
Bristol Myers Squibb Co |
Compuestos de piridopirimidinonilo sustituidos útiles como activadores de células t
|
MX2022002877A
(es)
|
2019-09-13 |
2022-08-08 |
Nimbus Saturn Inc |
Antagonistas de cinasa progenitora hematopoyetica 1 (hpk1) y sus usos.
|
JP2022548292A
(ja)
|
2019-09-19 |
2022-11-17 |
ブリストル-マイヤーズ スクイブ カンパニー |
酸性pHでVISTAと結合する抗体
|
PE20221784A1
(es)
|
2019-09-25 |
2022-11-22 |
Pfizer |
Moduladores de sting (estimulador de genes de interferon)
|
EP4048295A1
(en)
|
2019-10-25 |
2022-08-31 |
Iovance Biotherapeutics, Inc. |
Gene editing of tumor infiltrating lymphocytes and uses of same in immunotherapy
|
US20220411523A1
(en)
|
2019-11-13 |
2022-12-29 |
Hefei Hankemab Biotechnology Co., Ltd |
Molecule capable of binding to human 4-1bb and its application thereof
|
CN112898426A
(zh)
*
|
2019-11-19 |
2021-06-04 |
非同(成都)生物科技有限公司 |
人源化4-1bb单克隆抗体及其药物组合物
|
US11548870B2
(en)
|
2019-11-19 |
2023-01-10 |
Bristol-Myers Squibb Company |
Compounds useful as inhibitors of helios protein
|
MX2022006308A
(es)
|
2019-11-26 |
2022-06-22 |
Ikena Oncology Inc |
Derivados de carbazol polimorfos y usos de los mismos.
|
IL293357A
(en)
|
2019-11-26 |
2022-07-01 |
Bristol Myers Squibb Co |
Salts/crystals of (r)-n-(4-chlorophenyl)-2-((1s,4s)-4-(6-fluoroquinolin-4-yl)cyclohexyl)propanamide
|
IL293350A
(en)
|
2019-11-27 |
2022-07-01 |
Myst Therapeutics Llc |
A method for producing tumor-reactive t cells using modulatory substances
|
WO2021118990A1
(en)
|
2019-12-11 |
2021-06-17 |
Iovance Biotherapeutics, Inc. |
Processes for the production of tumor infiltrating lymphocytes (tils) and methods of using the same
|
JP2023509359A
(ja)
|
2019-12-17 |
2023-03-08 |
フラグシップ パイオニアリング イノベーションズ ブイ,インコーポレーテッド |
鉄依存性細胞分解の誘導物質との併用抗癌療法
|
EP4076524A4
(en)
|
2019-12-17 |
2023-11-29 |
Kymera Therapeutics, Inc. |
IRAQ DEGRADERS AND USES THEREOF
|
BR112022011651A2
(pt)
|
2019-12-17 |
2022-08-23 |
Kymera Therapeutics Inc |
Degradadores de irak e usos dos mesmos
|
ES2969732T3
(es)
|
2019-12-18 |
2024-05-22 |
Pfizer |
Régimen de tratamiento del cáncer una vez al día con un inhibidor de PRMT5
|
AR120823A1
(es)
|
2019-12-23 |
2022-03-23 |
Bristol Myers Squibb Co |
Compuestos bicíclicos sustituidos útiles como activadores de células t
|
TW202136242A
(zh)
|
2019-12-23 |
2021-10-01 |
美商凱麥拉醫療公司 |
Smarca降解劑及其用途
|
EP4081516A1
(en)
|
2019-12-23 |
2022-11-02 |
Bristol-Myers Squibb Company |
Substituted quinazolinyl compounds useful as t cell activators
|
CN115175907A
(zh)
|
2019-12-23 |
2022-10-11 |
百时美施贵宝公司 |
可用作t细胞激活剂的经取代的哌嗪衍生物
|
WO2021133748A1
(en)
|
2019-12-23 |
2021-07-01 |
Bristol-Myers Squibb Company |
Substituted quinolinonyl piperazine compounds useful as t cell activators
|
WO2021133752A1
(en)
|
2019-12-23 |
2021-07-01 |
Bristol-Myers Squibb Company |
Substituted heteroaryl compounds useful as t cell activators
|
JP2023517794A
(ja)
|
2020-01-06 |
2023-04-27 |
ハイファイバイオ(ホンコン)リミテッド |
抗tnfr2抗体及びその使用
|
WO2021139682A1
(en)
|
2020-01-07 |
2021-07-15 |
Hifibio (Hk) Limited |
Anti-galectin-9 antibody and uses thereof
|
BR112022012918A2
(pt)
|
2020-01-07 |
2022-09-06 |
Univ Texas |
Variantes de enzima de exaustão de metiltioadenosina/adenosina humana melhorada para terapia do câncer
|
JP2023510918A
(ja)
|
2020-01-15 |
2023-03-15 |
ブループリント メディシンズ コーポレイション |
Map4k1阻害剤
|
TW202144395A
(zh)
*
|
2020-02-12 |
2021-12-01 |
日商中外製藥股份有限公司 |
用於癌症之治療的抗cd137抗原結合分子
|
CA3168337A1
(en)
|
2020-02-17 |
2021-08-26 |
Marie-Andree Forget |
Methods for expansion of tumor infiltrating lymphocytes and use thereof
|
JP2023516636A
(ja)
|
2020-02-27 |
2023-04-20 |
ミスト セラピューティクス リミテッド ライアビリティ カンパニー |
腫瘍反応性t細胞のエクスビボ富化および増大のための方法ならびに関連するその組成物
|
EP4110826A1
(en)
|
2020-02-28 |
2023-01-04 |
Shanghai Henlius Biotech, Inc. |
Anti-cd137 constructs, multispecific antibody and uses thereof
|
AU2021225920A1
(en)
*
|
2020-02-28 |
2022-09-15 |
Shanghai Henlius Biotech, Inc. |
Anti-CD137 construct and use thereof
|
AU2021230289A1
(en)
|
2020-03-03 |
2022-09-29 |
PIC Therapeutics, Inc. |
eIF4E inhibitors and uses thereof
|
WO2021181233A2
(en)
|
2020-03-09 |
2021-09-16 |
Pfizer Inc. |
Fusion proteins and uses thereof
|
IL295569A
(en)
|
2020-03-19 |
2022-10-01 |
Arcus Biosciences Inc |
Tetralin and tetrahydroquinoline compounds as inhibitors of hif-2alpha
|
JP2023518423A
(ja)
|
2020-03-19 |
2023-05-01 |
カイメラ セラピューティクス, インコーポレイテッド |
Mdm2分解剤およびそれらの使用
|
TW202140441A
(zh)
|
2020-03-23 |
2021-11-01 |
美商必治妥美雅史谷比公司 |
經取代之側氧基異吲哚啉化合物
|
US20230272056A1
(en)
|
2020-04-09 |
2023-08-31 |
Merck Sharp & Dohme Llc |
Affinity matured anti-lap antibodies and uses thereof
|
EP4146793A1
(en)
|
2020-05-04 |
2023-03-15 |
Iovance Biotherapeutics, Inc. |
Selection of improved tumor reactive t-cells
|
WO2021226061A1
(en)
|
2020-05-04 |
2021-11-11 |
Iovance Biotherapeutics, Inc. |
Processes for production of tumor infiltrating lymphocytes and uses of the same in immunotherapy
|
KR20230008197A
(ko)
|
2020-05-13 |
2023-01-13 |
화이자 인코포레이티드 |
암을 치료하기 위한 방법, 요법 및 용도
|
MX2022015157A
(es)
|
2020-06-02 |
2023-01-16 |
Arcus Biosciences Inc |
Anticuerpos para tigit.
|
TW202210483A
(zh)
|
2020-06-03 |
2022-03-16 |
美商凱麥拉醫療公司 |
Irak降解劑之結晶型
|
WO2021258010A1
(en)
|
2020-06-19 |
2021-12-23 |
Gossamer Bio Services, Inc. |
Oxime compounds useful as t cell activators
|
CA3184366A1
(en)
|
2020-06-29 |
2022-01-06 |
Darby Rye Schmidt |
Viruses engineered to promote thanotransmission and their use in treating cancer
|
US11857535B2
(en)
|
2020-07-30 |
2024-01-02 |
Kymera Therapeutics, Inc. |
Methods of treating mutant lymphomas
|
CN116724051A
(zh)
|
2020-08-10 |
2023-09-08 |
上海寻百会生物技术有限公司 |
用于通过靶向igsf8来治疗自身免疫性疾病和癌症的组合物和方法
|
KR20230074721A
(ko)
|
2020-08-17 |
2023-05-31 |
바이사이클티엑스 리미티드 |
Nectin-4에 특이적인 이환 콘쥬게이트 및 이의 용도
|
MX2023003034A
(es)
|
2020-09-14 |
2023-04-10 |
Pfizer |
Metodos, terapias y usos para tratar el cancer.
|
CN114195894A
(zh)
*
|
2020-09-17 |
2022-03-18 |
普米斯生物技术(珠海)有限公司 |
一种靶向4-1bb的抗体及其应用
|
CN114195900B
(zh)
|
2020-09-17 |
2024-02-23 |
普米斯生物技术(珠海)有限公司 |
一种抗4-1bb/pd-l1双特异性抗体及其用途
|
WO2022076606A1
(en)
|
2020-10-06 |
2022-04-14 |
Iovance Biotherapeutics, Inc. |
Treatment of nsclc patients with tumor infiltrating lymphocyte therapies
|
CA3195019A1
(en)
|
2020-10-06 |
2022-04-14 |
Maria Fardis |
Treatment of nsclc patients with tumor infiltrating lymphocyte therapies
|
CA3198456A1
(en)
|
2020-10-14 |
2022-04-21 |
Five Prime Therapeutics, Inc. |
Anti-c-c chemokine receptor 8 (ccr8) antibodies and methods of use thereof
|
EP3988568A1
(en)
|
2020-10-21 |
2022-04-27 |
Numab Therapeutics AG |
Combination treatment
|
WO2022120353A1
(en)
|
2020-12-02 |
2022-06-09 |
Ikena Oncology, Inc. |
Tead inhibitors and uses thereof
|
IL303376A
(en)
|
2020-12-02 |
2023-08-01 |
Ikena Oncology Inc |
TEAD inhibitors and their uses
|
JP2024501452A
(ja)
|
2020-12-11 |
2024-01-12 |
アイオバンス バイオセラピューティクス,インコーポレイテッド |
Braf阻害剤及び/またはmek阻害剤と併用した腫瘍浸潤リンパ球治療によるがん患者の治療
|
WO2022130206A1
(en)
|
2020-12-16 |
2022-06-23 |
Pfizer Inc. |
TGFβr1 INHIBITOR COMBINATION THERAPIES
|
WO2022133083A1
(en)
|
2020-12-16 |
2022-06-23 |
Gossamer Bio Services, Inc. |
Compounds useful as t cell activators
|
US20240123067A1
(en)
|
2020-12-17 |
2024-04-18 |
Iovance Biotherapeutics, Inc. |
Treatment of cancers with tumor infiltrating lymphocyte therapies
|
WO2022133140A1
(en)
|
2020-12-17 |
2022-06-23 |
Iovance Biotherapeutics, Inc. |
Treatment with tumor infiltrating lymphocyte therapies in combination with ctla-4 and pd-1 inhibitors
|
TW202241488A
(zh)
|
2021-01-11 |
2022-11-01 |
英商拜斯科技技術開發有限公司 |
治療癌症之方法
|
WO2022153161A1
(en)
|
2021-01-14 |
2022-07-21 |
Pfizer Inc. |
Treatment of cancer using a prmt5 inhibitor
|
MX2023009059A
(es)
|
2021-02-02 |
2023-09-15 |
Liminal Biosciences Ltd |
Antagonistas de gpr84 y usos de estos.
|
AU2022216810A1
(en)
|
2021-02-02 |
2023-08-24 |
Liminal Biosciences Limited |
Gpr84 antagonists and uses thereof
|
US20240109899A1
(en)
|
2021-02-04 |
2024-04-04 |
Bristol-Myers Squibb Company |
Benzofuran compounds as sting agonists
|
EP4288140A1
(en)
|
2021-02-05 |
2023-12-13 |
Iovance Biotherapeutics, Inc. |
Adjuvant therapy for cancer
|
EP4291558A1
(en)
|
2021-02-12 |
2023-12-20 |
F. Hoffmann-La Roche AG |
Bicyclic tetrahydroazepine derivatives for the treatment of cancer
|
KR20230145446A
(ko)
|
2021-02-15 |
2023-10-17 |
카이메라 쎄라퓨틱스 인코포레이티드 |
Irak4 분해제 및 이의 용도
|
CN117295737A
(zh)
|
2021-03-05 |
2023-12-26 |
林伯士萨顿公司 |
Hpk1拮抗剂和其用途
|
WO2022187741A2
(en)
|
2021-03-05 |
2022-09-09 |
Iovance Biotherapeutics, Inc. |
Tumor storage and cell culture compositions
|
JP2024510176A
(ja)
|
2021-03-08 |
2024-03-06 |
ブループリント メディシンズ コーポレイション |
Map4k1阻害剤
|
US11918582B2
(en)
|
2021-03-15 |
2024-03-05 |
Rapt Therapeutics, Inc. |
Pyrazole pyrimidine compounds and uses thereof
|
US11964978B2
(en)
|
2021-03-18 |
2024-04-23 |
Pfizer Inc. |
Modulators of STING (stimulator of interferon genes)
|
EP4313109A1
(en)
|
2021-03-31 |
2024-02-07 |
Flagship Pioneering Innovations V, Inc. |
Thanotransmission polypeptides and their use in treating cancer
|
AU2022253450A1
(en)
|
2021-04-05 |
2023-11-16 |
Bristol-Myers Squibb Company |
Pyridinyl substituted oxoisoindoline compounds for the treatment of cancer
|
BR112023020077A2
(pt)
|
2021-04-06 |
2023-11-14 |
Bristol Myers Squibb Co |
Compostos de oxoisoindolina substituída por piridinila
|
EP4323066A1
(en)
|
2021-04-16 |
2024-02-21 |
Ikena Oncology, Inc. |
Mek inhibitors and uses thereof
|
WO2022225981A2
(en)
|
2021-04-19 |
2022-10-27 |
Iovance Biotherapeutics, Inc. |
Chimeric costimulatory receptors, chemokine receptors, and the use of same in cellular immunotherapies
|
EP4340850A1
(en)
|
2021-05-17 |
2024-03-27 |
Iovance Biotherapeutics, Inc. |
Pd-1 gene-edited tumor infiltrating lymphocytes and uses of same in immunotherapy
|
TW202313602A
(zh)
|
2021-05-21 |
2023-04-01 |
美商阿克思生物科學有限公司 |
Axl化合物
|
EP4341262A1
(en)
|
2021-05-21 |
2024-03-27 |
Arcus Biosciences, Inc. |
Axl inhibitor compounds
|
KR20240049794A
(ko)
|
2021-06-07 |
2024-04-17 |
프로비던스 헬스 앤드 서비시즈 - 오레곤 |
Cxcr5, pd-1, 및 icos 발현 종양 반응성 cd4 t 세포 및 그의 용도
|
AU2022303363A1
(en)
|
2021-06-29 |
2024-01-18 |
Flagship Pioneering Innovations V, Inc. |
Immune cells engineered to promote thanotransmission and uses thereof
|
US20230112729A1
(en)
|
2021-07-14 |
2023-04-13 |
Blueprint Medicines Corporation |
Map4k1 inhibitors
|
AR126453A1
(es)
|
2021-07-15 |
2023-10-11 |
Blueprint Medicines Corp |
Inhibidores de map4k1
|
EP4377446A1
(en)
|
2021-07-28 |
2024-06-05 |
Iovance Biotherapeutics, Inc. |
Treatment of cancer patients with tumor infiltrating lymphocyte therapies in combination with kras inhibitors
|
WO2023028235A1
(en)
|
2021-08-25 |
2023-03-02 |
PIC Therapeutics, Inc. |
Eif4e inhibitors and uses thereof
|
US20230134932A1
(en)
|
2021-08-25 |
2023-05-04 |
PIC Therapeutics, Inc. |
Eif4e inhibitors and uses thereof
|
WO2023049862A1
(en)
|
2021-09-24 |
2023-03-30 |
Iovance Biotherapeutics, Inc. |
Expansion processes and agents for tumor infiltrating lymphocytes
|
AU2022365133A1
(en)
*
|
2021-10-12 |
2024-05-02 |
Concept To Medicine Biotech Co., Ltd. |
Single-domain 4-1bb antibodies
|
WO2023064958A1
(en)
|
2021-10-15 |
2023-04-20 |
Compugen Ltd. |
Combination therapy with anti-pvrig antibodies formulations, anti-tigit antibodies, and anti-pd-1 antibodies
|
WO2023077015A2
(en)
|
2021-10-27 |
2023-05-04 |
Iovance Biotherapeutics, Inc. |
Systems and methods for coordinating manufacturing of cells for patient-specific immunotherapy
|
WO2023077046A1
(en)
|
2021-10-29 |
2023-05-04 |
Arcus Biosciences, Inc. |
Inhibitors of hif-2alpha and methods of use thereof
|
CA3237410A1
(en)
|
2021-11-10 |
2023-05-19 |
Friedrich Graf Finck VON FINCKENSTEIN |
Methods of expansion treatment utilizing cd8 tumor infiltrating lymphocytes
|
WO2023114984A1
(en)
|
2021-12-17 |
2023-06-22 |
Ikena Oncology, Inc. |
Tead inhibitors and uses thereof
|
WO2023122777A1
(en)
|
2021-12-22 |
2023-06-29 |
Gossamer Bio Services, Inc. |
Oxime derivatives useful as t cell activators
|
WO2023122772A1
(en)
|
2021-12-22 |
2023-06-29 |
Gossamer Bio Services, Inc. |
Oxime derivatives useful as t cell activators
|
WO2023122778A1
(en)
|
2021-12-22 |
2023-06-29 |
Gossamer Bio Services, Inc. |
Pyridazinone derivatives useful as t cell activators
|
WO2023147486A1
(en)
|
2022-01-28 |
2023-08-03 |
Iovance Biotherapeutics, Inc. |
Tumor infiltrating lymphocytes engineered to express payloads
|
WO2023150186A1
(en)
|
2022-02-01 |
2023-08-10 |
Arvinas Operations, Inc. |
Dgk targeting compounds and uses thereof
|
WO2023173057A1
(en)
|
2022-03-10 |
2023-09-14 |
Ikena Oncology, Inc. |
Mek inhibitors and uses thereof
|
WO2023173053A1
(en)
|
2022-03-10 |
2023-09-14 |
Ikena Oncology, Inc. |
Mek inhibitors and uses thereof
|
WO2023201369A1
(en)
|
2022-04-15 |
2023-10-19 |
Iovance Biotherapeutics, Inc. |
Til expansion processes using specific cytokine combinations and/or akti treatment
|
WO2023211889A1
(en)
|
2022-04-25 |
2023-11-02 |
Ikena Oncology, Inc. |
Polymorphic compounds and uses thereof
|
WO2023215719A1
(en)
|
2022-05-02 |
2023-11-09 |
Arcus Biosciences, Inc. |
Anti-tigit antibodies and uses of the same
|
WO2023230205A1
(en)
|
2022-05-25 |
2023-11-30 |
Ikena Oncology, Inc. |
Mek inhibitors and uses thereof
|
US20240124490A1
(en)
|
2022-07-15 |
2024-04-18 |
Arcus Biosciences, Inc. |
Inhibitors of hpk1 and methods of use thereof
|
WO2024020034A1
(en)
|
2022-07-20 |
2024-01-25 |
Arcus Biosciences, Inc. |
Cbl-b inhibitors and methods of use thereof
|
WO2024030758A1
(en)
|
2022-08-01 |
2024-02-08 |
Iovance Biotherapeutics, Inc. |
Chimeric costimulatory receptors, chemokine receptors, and the use of same in cellular immunotherapies
|
WO2024028363A1
(en)
|
2022-08-02 |
2024-02-08 |
Liminal Biosciences Limited |
Heteroaryl carboxamide and related gpr84 antagonists and uses thereof
|
WO2024028365A1
(en)
|
2022-08-02 |
2024-02-08 |
Liminal Biosciences Limited |
Substituted pyridone gpr84 antagonists and uses thereof
|
WO2024028364A1
(en)
|
2022-08-02 |
2024-02-08 |
Liminal Biosciences Limited |
Aryl-triazolyl and related gpr84 antagonists and uses thereof
|
WO2024036100A1
(en)
|
2022-08-08 |
2024-02-15 |
Bristol-Myers Squibb Company |
Substituted tetrazolyl compounds useful as t cell activators
|
WO2024036101A1
(en)
|
2022-08-09 |
2024-02-15 |
Bristol-Myers Squibb Company |
Tertiary amine substituted bicyclic compounds useful as t cell activators
|
WO2024033388A1
(en)
|
2022-08-11 |
2024-02-15 |
F. Hoffmann-La Roche Ag |
Bicyclic tetrahydrothiazepine derivatives
|
WO2024033457A1
(en)
|
2022-08-11 |
2024-02-15 |
F. Hoffmann-La Roche Ag |
Bicyclic tetrahydrothiazepine derivatives
|
WO2024033458A1
(en)
|
2022-08-11 |
2024-02-15 |
F. Hoffmann-La Roche Ag |
Bicyclic tetrahydroazepine derivatives
|
WO2024033389A1
(en)
|
2022-08-11 |
2024-02-15 |
F. Hoffmann-La Roche Ag |
Bicyclic tetrahydrothiazepine derivatives
|
WO2024040194A1
(en)
|
2022-08-17 |
2024-02-22 |
Capstan Therapeutics, Inc. |
Conditioning for in vivo immune cell engineering
|
WO2024077191A1
(en)
|
2022-10-05 |
2024-04-11 |
Flagship Pioneering Innovations V, Inc. |
Nucleic acid molecules encoding trif and additionalpolypeptides and their use in treating cancer
|
WO2024081385A1
(en)
|
2022-10-14 |
2024-04-18 |
Arcus Biosciences, Inc. |
Hpk1 inhibitors and methods of use thereof
|
WO2024086718A1
(en)
|
2022-10-20 |
2024-04-25 |
Arcus Biosciences, Inc. |
Lyophilized formulations of cd73 compounds
|