|
US3272781A
(en)
|
1963-08-07 |
1966-09-13 |
American Potash & Chem Corp |
Boroureas of phosphinoborine polymers
|
|
FR1425700A
(fr)
|
1965-02-22 |
1966-01-24 |
Basf Ag |
Composés formant des complexes métalliques et procédé pour les préparer et les utiliser
|
|
US4208328A
(en)
|
1978-04-27 |
1980-06-17 |
General Electric Company |
Alkyl 3,5-dihydroxy-4-(2-benzothiazolyl)benzoates
|
|
US4789711A
(en)
|
1986-12-02 |
1988-12-06 |
Ciba-Geigy Corporation |
Multifunctional epoxide resins
|
|
DE3828535A1
(de)
|
1988-08-23 |
1990-03-08 |
Basf Ag |
Benzimidazol-2-carbonsaeureanilide, ihre verwendung als lichtschutzmittel fuer organisches material und mit diesen aniliden stabilisiertes organisches material
|
|
US5077164A
(en)
|
1989-06-21 |
1991-12-31 |
Minolta Camera Kabushiki Kaisha |
Photosensitive member containing an azo dye
|
|
DE69421982T2
(de)
|
1993-09-20 |
2000-03-30 |
Fuji Photo Film Co., Ltd. |
Positiv arbeitende Photoresistzusammensetzung
|
|
JP3461397B2
(ja)
|
1995-01-11 |
2003-10-27 |
富士写真フイルム株式会社 |
ポジ型フオトレジスト組成物
|
|
EP0946587A2
(en)
|
1996-12-16 |
1999-10-06 |
Fujisawa Pharmaceutical Co., Ltd. |
New amide compounds
|
|
JPH10316853A
(ja)
|
1997-05-15 |
1998-12-02 |
Sumitomo Bakelite Co Ltd |
半導体多層配線用層間絶縁膜樹脂組成物及び該絶縁膜の製造方法
|
|
WO1999018096A1
(en)
|
1997-10-02 |
1999-04-15 |
Merck & Co., Inc. |
Inhibitors of prenyl-protein transferase
|
|
AU2745899A
(en)
|
1998-03-05 |
1999-09-20 |
Nissan Chemical Industries Ltd. |
Anilide compounds and herbicide
|
|
JP2000128986A
(ja)
|
1998-10-28 |
2000-05-09 |
Sumitomo Bakelite Co Ltd |
ポリベンゾオキサゾール前駆体及びポリベンゾオキサゾール
|
|
JP2000128987A
(ja)
|
1998-10-28 |
2000-05-09 |
Sumitomo Bakelite Co Ltd |
ポリベンゾオキサゾール前駆体及びポリベンゾオキサゾール
|
|
JP2000128984A
(ja)
|
1998-10-28 |
2000-05-09 |
Sumitomo Bakelite Co Ltd |
ポリベンゾオキサゾール前駆体及び樹脂
|
|
US6297351B1
(en)
|
1998-12-17 |
2001-10-02 |
Sumitomo Bakelite Company Limited |
Polybenzoxazole resin and precursor thereof
|
|
WO2000035886A2
(en)
|
1998-12-18 |
2000-06-22 |
Axys Pharmaceuticals, Inc. |
(hetero)aryl-bicyclic heteroaryl derivatives, their preparation and their use as protease inhibitors
|
|
JP2000212281A
(ja)
|
1999-01-27 |
2000-08-02 |
Sumitomo Bakelite Co Ltd |
ポリベンゾオキサゾ―ル前駆体及びポリベンゾオキサゾ―ル樹脂
|
|
AU6000900A
(en)
|
1999-07-23 |
2001-02-13 |
Astrazeneca Uk Limited |
Carbazole derivatives and their use as neuropeptide y5 receptor ligands
|
|
JP2001114893A
(ja)
|
1999-10-15 |
2001-04-24 |
Sumitomo Bakelite Co Ltd |
ポリベンゾオキサゾール樹脂およびその前駆体
|
|
US6372907B1
(en)
|
1999-11-03 |
2002-04-16 |
Apptera Corporation |
Water-soluble rhodamine dye peptide conjugates
|
|
JP2001163975A
(ja)
|
1999-12-03 |
2001-06-19 |
Sumitomo Bakelite Co Ltd |
ポリベンゾオキサゾール樹脂及びその前駆体
|
|
EP1162196A4
(en)
|
1999-12-27 |
2003-04-16 |
Japan Tobacco Inc |
COMPOUNDS WITH JOINED CYCLES AND THEIR USE AS MEDICAMENTS
|
|
WO2001057038A1
(de)
|
2000-02-01 |
2001-08-09 |
Basf Aktiengesellschaft |
Heterozyklische verbindungen und deren anwendung als parp-inhibitoren
|
|
US6521618B2
(en)
|
2000-03-28 |
2003-02-18 |
Wyeth |
3-cyanoquinolines, 3-cyano-1,6-naphthyridines, and 3-cyano-1,7-naphthyridines as protein kinase inhibitors
|
|
US6908929B2
(en)
|
2000-03-31 |
2005-06-21 |
Ortho-Mcneil Pharmaceutical, Inc. |
Phenyl-substituted imidazopyridines
|
|
EP1278734A2
(en)
|
2000-04-24 |
2003-01-29 |
Merck Frosst Canada & Co. |
Method of treatment using phenyl and biaryl derivatives as prostaglandin e inhibitors and compounds useful therefore
|
|
ATE273695T1
(de)
|
2000-06-28 |
2004-09-15 |
Smithkline Beecham Plc |
Nassvermahlung
|
|
WO2002014321A1
(en)
|
2000-08-11 |
2002-02-21 |
The Regents Of The University Of California |
Use of stat-6 inhibitors as therapeutic agents
|
|
AU2002224927A1
(en)
|
2000-12-13 |
2002-06-24 |
Basf Aktiengesellschaft |
Use of substituted imidazoazines, novel imidazoazines, methods for the production thereof, and agents containing these compounds
|
|
EP1341788B1
(en)
|
2000-12-15 |
2005-08-10 |
Glaxo Group Limited |
Pyrazolopyridines
|
|
SE0100567D0
(sv)
|
2001-02-20 |
2001-02-20 |
Astrazeneca Ab |
Compounds
|
|
EP1373240B1
(en)
|
2001-03-14 |
2005-06-15 |
Eli Lilly And Company |
Retinoid x receptor modulators
|
|
US7034030B2
(en)
|
2001-03-30 |
2006-04-25 |
Smithkline Beecham Corporation |
Pyralopyridines, process for their preparation and use as therapeutic compounds
|
|
JP4219171B2
(ja)
|
2001-04-10 |
2009-02-04 |
スミスクライン ビーチャム コーポレーション |
抗ウイルス性ピラゾロピリジン化合物
|
|
JP2002316966A
(ja)
|
2001-04-19 |
2002-10-31 |
Ueno Seiyaku Oyo Kenkyusho:Kk |
ビナフトール誘導体およびその製法
|
|
ATE296826T1
(de)
|
2001-04-27 |
2005-06-15 |
Smithkline Beecham Corp |
Pyrazolo(1,5)pyridinderivate
|
|
AR035543A1
(es)
|
2001-06-26 |
2004-06-16 |
Japan Tobacco Inc |
Agente terapeutico para la hepatitis c que comprende un compuesto de anillo condensado, compuesto de anillo condensado, composicion farmaceutica que lo comprende, compuestos de benzimidazol, tiazol y bifenilo utiles como intermediarios para producir dichos compuestos, uso del compuesto de anillo con
|
|
DE60220525T2
(de)
|
2001-09-07 |
2008-02-07 |
Smithkline Beecham Corp. |
Pyrazolo-pyridine für die behandlung von herpes-ansteckungen
|
|
TWI331526B
(en)
|
2001-09-21 |
2010-10-11 |
Bristol Myers Squibb Pharma Co |
Lactam-containing compounds and derivatives thereof as factor xa inhibitors
|
|
AU2002334969A1
(en)
|
2001-10-09 |
2003-04-22 |
Sylvie Barchechath |
Use of stat-6 inhibitors as therapeutic agents
|
|
MXPA04003419A
(es)
|
2001-10-09 |
2004-07-08 |
Upjohn Co |
Tetrahidro y hexahidro-carbazoles sustituidos con arilsulfonilo como ligandos del receptor 5-ht-6.
|
|
WO2003042402A2
(en)
|
2001-11-13 |
2003-05-22 |
Dana-Farber Cancer Institute, Inc. |
Agents that modulate immune cell activation and methods of use thereof
|
|
JP4024579B2
(ja)
|
2002-01-22 |
2007-12-19 |
住友ベークライト株式会社 |
プラスチック光導波路用材料及び光導波路
|
|
AU2003223602B8
(en)
|
2002-04-11 |
2010-05-27 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of serine proteases, particularly hepatitis C virus NS3-NS4 protease
|
|
EP1505068A4
(en)
|
2002-04-23 |
2008-03-19 |
Shionogi & Co |
PYRAZOLO (1,5-a) PYRIMIDINE DERIVATIVE AND INHIBITOR OF NAD (P) H OXIDASE CONTAINING SAID DERIVATIVE
|
|
US20060004010A1
(en)
|
2002-07-10 |
2006-01-05 |
Hiromu Habashita |
Ccr4 antagonist and medical use thereof
|
|
AU2003249244A1
(en)
|
2002-07-15 |
2004-02-02 |
Combinatorx, Incorporated |
Methods for the treatment of neoplasms
|
|
JP2004059761A
(ja)
|
2002-07-30 |
2004-02-26 |
Sumitomo Bakelite Co Ltd |
ポリベンゾオキサゾール樹脂、その前駆体及びこれらを用いた光導波路材料並びに光導波路
|
|
JP2004091369A
(ja)
|
2002-08-30 |
2004-03-25 |
Sumitomo Pharmaceut Co Ltd |
新規ビフェニル化合物
|
|
EP1547996A4
(en)
|
2002-08-30 |
2006-08-02 |
Bf Res Inst Inc |
DIAGNOSTIC PROBES AND REMEDIES FOR DISEASES IN WHICH PRION PROTEIN IS ACCUMULATED, AND ANIMAL FEVERING FOR PRION PROTEIN
|
|
US7153863B2
(en)
|
2002-10-03 |
2006-12-26 |
Smithkline Beecham Corporation |
Therapeutic compounds based on pyrazolopyridline derivatives
|
|
EP1551842A1
(en)
|
2002-10-15 |
2005-07-13 |
Smithkline Beecham Corporation |
Pyradazine compounds as gsk-3 inhibitors
|
|
CN1753912B
(zh)
|
2002-12-23 |
2011-11-02 |
惠氏公司 |
抗pd-1抗体及其用途
|
|
KR100624406B1
(ko)
|
2002-12-30 |
2006-09-18 |
삼성에스디아이 주식회사 |
비페닐 유도체 및 이를 채용한 유기 전계 발광 소자
|
|
US7320989B2
(en)
|
2003-02-28 |
2008-01-22 |
Encysive Pharmaceuticals, Inc. |
Pyridine, pyrimidine, quinoline, quinazoline, and naphthalene urotensin-II receptor antagonists
|
|
US7078419B2
(en)
|
2003-03-10 |
2006-07-18 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Cytokine inhibitors
|
|
TW200505902A
(en)
|
2003-03-20 |
2005-02-16 |
Schering Corp |
Cannabinoid receptor ligands
|
|
JP4595288B2
(ja)
|
2003-03-25 |
2010-12-08 |
住友ベークライト株式会社 |
ポリベンゾオキサゾール樹脂、その前駆体及びこれらを用いた光導波路材料並びに光導波路
|
|
OA13154A
(en)
|
2003-04-11 |
2006-12-13 |
Glenmark Pharmaceuticals Sa |
Novel heterocyclic compounds useful for the treatment of inflammatory and allergic disorders: process for their preparation and pharmaceutical compositions containing them.
|
|
BRPI0410439A
(pt)
|
2003-05-19 |
2006-06-06 |
Irm Llc |
compostos e composições imunossupressoras
|
|
JP2005002330A
(ja)
|
2003-05-19 |
2005-01-06 |
Sumitomo Electric Ind Ltd |
光学樹脂材料、光学素子、光モジュール、フッ素化ポリマー前駆体及びフッ素化ポリマー
|
|
US7405295B2
(en)
|
2003-06-04 |
2008-07-29 |
Cgi Pharmaceuticals, Inc. |
Certain imidazo[1,2-a]pyrazin-8-ylamines and method of inhibition of Bruton's tyrosine kinase by such compounds
|
|
US20060183746A1
(en)
|
2003-06-04 |
2006-08-17 |
Currie Kevin S |
Certain imidazo[1,2-a]pyrazin-8-ylamines and method of inhibition of Bruton's tyrosine kinase by such compounds
|
|
US20070010573A1
(en)
|
2003-06-23 |
2007-01-11 |
Xianqi Kong |
Methods and compositions for treating amyloid-related diseases
|
|
US7393848B2
(en)
|
2003-06-30 |
2008-07-01 |
Cgi Pharmaceuticals, Inc. |
Certain heterocyclic substituted imidazo[1,2-A]pyrazin-8-ylamines and methods of inhibition of Bruton's tyrosine kinase by such compounds
|
|
WO2005004863A1
(en)
|
2003-07-11 |
2005-01-20 |
Merck Patent Gmbh |
Benzimidazole carboxamides as raf kinase inhibitors
|
|
US7276608B2
(en)
|
2003-07-11 |
2007-10-02 |
Bristol-Myers Squibb Company |
Tetrahydroquinoline derivatives as cannabinoid receptor modulators
|
|
EP1661879A4
(en)
|
2003-08-04 |
2006-11-29 |
Ono Pharmaceutical Co |
A DIPHENYL ETHER COMPOUND, PROCESS FOR THE PRODUCTION AND USE THEREOF
|
|
WO2005014543A1
(ja)
|
2003-08-06 |
2005-02-17 |
Japan Tobacco Inc. |
縮合環化合物及びそのｈｃｖポリメラーゼ阻害剤としての利用
|
|
US7504401B2
(en)
|
2003-08-29 |
2009-03-17 |
Locus Pharmaceuticals, Inc. |
Anti-cancer agents and uses thereof
|
|
US7749999B2
(en)
|
2003-09-11 |
2010-07-06 |
Itherx Pharmaceuticals, Inc. |
Alpha-ketoamides and derivatives thereof
|
|
AU2004279427B2
(en)
|
2003-10-08 |
2008-07-03 |
Irm Llc |
Compounds and compositions as protein kinase inhibitors
|
|
JPWO2005040135A1
(ja)
|
2003-10-24 |
2007-03-08 |
小野薬品工業株式会社 |
抗ストレス薬およびその医薬用途
|
|
US20050288295A1
(en)
|
2003-11-11 |
2005-12-29 |
Currie Kevin S |
Certain imidazo[1,2-a]pyrazin-8-ylamines, method of making, and method of use thereof
|
|
WO2005063710A1
(de)
|
2003-12-23 |
2005-07-14 |
Basf Aktiengesellschaft |
3-trifluormethylpicolinsäureanilide und ihre verwendung als fungizide
|
|
EP1715867A4
(en)
|
2004-02-12 |
2009-04-15 |
Merck & Co Inc |
BIPYRIDYLAMIDE AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTOR-5
|
|
JPWO2005077948A1
(ja)
|
2004-02-16 |
2008-01-10 |
第一製薬株式会社 |
抗真菌作用複素環化合物
|
|
GB0403864D0
(en)
|
2004-02-20 |
2004-03-24 |
Ucl Ventures |
Modulator
|
|
JP2005248082A
(ja)
|
2004-03-05 |
2005-09-15 |
Sumitomo Electric Ind Ltd |
ポリベンゾオキサゾール樹脂前駆体の製造方法およびポリベンゾオキサゾール樹脂の製造方法
|
|
US20050250820A1
(en)
|
2004-03-08 |
2005-11-10 |
Amgen Inc. |
Therapeutic modulation of PPARgamma activity
|
|
WO2005086808A2
(en)
|
2004-03-08 |
2005-09-22 |
The University Of North Carolina At Chapel Hill |
NOVEL DICATIONIC IMIDAZO[1,2-a]PYRIDINES AND 5,6,7,8-TETRAHYDRO-IMIDAZO[1,2a]PYRIDINES AS ANTIPROTOZOAL AGENTS
|
|
AU2005230902A1
(en)
|
2004-03-31 |
2005-10-20 |
Janssen Pharmaceutica, N.V. |
Non-imidazole heterocyclic compounds as histamine H3-receptor ligands
|
|
JP2005290301A
(ja)
|
2004-04-02 |
2005-10-20 |
Sumitomo Electric Ind Ltd |
ポリベンゾオキサゾール樹脂前駆体の製造方法およびポリベンゾオキサゾール樹脂の製造方法
|
|
WO2005099656A2
(en)
|
2004-04-06 |
2005-10-27 |
The Procter & Gamble Company |
Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof
|
|
NZ550114A
(en)
|
2004-04-20 |
2011-02-25 |
Transtech Pharma Inc |
Substituted thiazole and pyrimidine derivatives as melanocortin receptor modulators
|
|
DE102004021716A1
(de)
|
2004-04-30 |
2005-12-01 |
Grünenthal GmbH |
Substituierte Imidazo[1,2-a]pyridin-Verbindungen und Arzneimittel enthaltend substituierte Imidazo[1,2-a]pyridin-Verbindungen
|
|
WO2005108387A2
(en)
|
2004-05-03 |
2005-11-17 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Cytokine inhibitors
|
|
TW200626142A
(en)
|
2004-09-21 |
2006-08-01 |
Glaxo Group Ltd |
Chemical compounds
|
|
MX2007003371A
(es)
|
2004-09-23 |
2007-05-07 |
Wyeth Corp |
Derivados de carbazol y ciclopentaindol para tratar infeccion con virus de hepatitis c.
|
|
ATE479687T1
(de)
|
2004-10-15 |
2010-09-15 |
Takeda Pharmaceutical |
Kinaseinhibitoren
|
|
CA2587192A1
(en)
|
2004-11-10 |
2006-05-18 |
Cgi Pharmaceuticals, Inc. |
Imidazo[1 , 2-a] pyrazin-8-ylamines useful as modulators of kinase activity
|
|
DE102004054665A1
(de)
|
2004-11-12 |
2006-05-18 |
Bayer Cropscience Gmbh |
Substituierte bi- und tricyclische Pyrazol-Derivate Verfahren zur Herstellung und Verwendung als Herbizide und Pflanzenwachstumsregulatoren
|
|
AU2006218403A1
(en)
|
2005-03-03 |
2006-09-08 |
Sirtris Pharmaceuticals, Inc. |
Fused heterocyclic compounds and their use as sirtuin modulators
|
|
CA2601628C
(en)
|
2005-03-10 |
2014-05-13 |
Cgi Pharmaceuticals, Inc. |
Certain substituted amides, method of making, and method of use thereof
|
|
JP2006290883A
(ja)
|
2005-03-17 |
2006-10-26 |
Nippon Nohyaku Co Ltd |
置換ヘテロ環カルボン酸アニリド誘導体、その中間体及び農園芸用薬剤並びにその使用方法
|
|
JP5079500B2
(ja)
|
2005-04-28 |
2012-11-21 |
協和発酵キリン株式会社 |
２−アミノキナゾリン誘導体
|
|
RU2494107C2
(ru)
|
2005-05-09 |
2013-09-27 |
Оно Фармасьютикал Ко., Лтд. |
Моноклональные антитела человека к белку программируемой смерти 1 (pd-1) и способы лечения рака с использованием анти-pd-1-антител самостоятельно или в комбинации с другими иммунотерапевтическими средствами
|
|
EP1902056A2
(en)
|
2005-05-20 |
2008-03-26 |
Array Biopharma, Inc. |
Raf inhibitor compounds and methods of use thereof
|
|
CN104356236B
(zh)
|
2005-07-01 |
2020-07-03 |
E.R.施贵宝&圣斯有限责任公司 |
抗程序性死亡配体1(pd-l1)的人单克隆抗体
|
|
US20080220968A1
(en)
|
2005-07-05 |
2008-09-11 |
Ge Healthcare Bio-Sciences Ab |
[1, 2, 4] Triazolo [1, 5-A] Pyrimidine Derivatives as Chromatographic Adsorbent for the Selective Adsorption of Igg
|
|
WO2007034282A2
(en)
|
2005-09-19 |
2007-03-29 |
Pfizer Products Inc. |
Diaryl-imidazole compounds condensed with a heterocycle as c3a receptor antagonists
|
|
US7723336B2
(en)
|
2005-09-22 |
2010-05-25 |
Bristol-Myers Squibb Company |
Fused heterocyclic compounds useful as kinase modulators
|
|
US20070078136A1
(en)
|
2005-09-22 |
2007-04-05 |
Bristol-Myers Squibb Company |
Fused heterocyclic compounds useful as kinase modulators
|
|
RU2416603C9
(ru)
|
2005-10-25 |
2012-06-20 |
Сионоги Энд Ко., Лтд. |
Производные аминодигидротиазина
|
|
US8518964B2
(en)
|
2005-11-22 |
2013-08-27 |
Merck Sharp & Dohme Corp. |
Tricyclic compounds useful as inhibitors of kinases
|
|
WO2007067711A2
(en)
|
2005-12-08 |
2007-06-14 |
Amphora Discovery Corporation |
Certain chemical entities, compositions, and methods for modulating trpv1
|
|
EP1961745A1
(en)
|
2005-12-12 |
2008-08-27 |
Ono Pharmaceutical Co., Ltd. |
Bicyclic heterocyclic compound
|
|
US20090281075A1
(en)
|
2006-02-17 |
2009-11-12 |
Pharmacopeia, Inc. |
Isomeric purinones and 1h-imidazopyridinones as pkc-theta inhibitors
|
|
WO2007096764A2
(en)
|
2006-02-27 |
2007-08-30 |
Glenmark Pharmaceuticals S.A. |
Bicyclic heteroaryl derivatives as cannabinoid receptor modulators
|
|
WO2007102531A1
(ja)
|
2006-03-08 |
2007-09-13 |
Takeda Pharmaceutical Company Limited |
併用薬
|
|
JP2009531390A
(ja)
|
2006-03-31 |
2009-09-03 |
ノバルティス アクチエンゲゼルシャフト |
有機化合物
|
|
US7700616B2
(en)
|
2006-05-08 |
2010-04-20 |
Molecular Neuroimaging, Llc. |
Compounds and amyloid probes thereof for therapeutic and imaging uses
|
|
CA2691214A1
(en)
|
2006-06-09 |
2007-12-21 |
Kemia, Inc. |
Therapy using cytokine inhibitors
|
|
US20080280891A1
(en)
|
2006-06-27 |
2008-11-13 |
Locus Pharmaceuticals, Inc. |
Anti-cancer agents and uses thereof
|
|
EP2044061A2
(en)
|
2006-07-20 |
2009-04-08 |
Mehmet Kahraman |
Benzothiophene inhibitors of rho kinase
|
|
DE102006035018B4
(de)
|
2006-07-28 |
2009-07-23 |
Novaled Ag |
Oxazol-Triplett-Emitter für OLED-Anwendungen
|
|
WO2008021745A2
(en)
|
2006-08-16 |
2008-02-21 |
Itherx Pharmaceuticals, Inc. |
Hepatitis c virus entry inhibitors
|
|
TWI389895B
(zh)
|
2006-08-21 |
2013-03-21 |
Infinity Discovery Inc |
抑制ｂｃｌ蛋白質與結合夥伴間之交互作用的化合物及方法
|
|
WO2008027812A2
(en)
|
2006-08-28 |
2008-03-06 |
Forest Laboratories Holdings Limited |
Imidazopyridine and imidazopyrimidine derivatives
|
|
US7838523B2
(en)
|
2006-09-11 |
2010-11-23 |
Cgi Pharmaceuticals, Inc. |
Certain substituted amides, method of making, and method of use thereof
|
|
AR063706A1
(es)
|
2006-09-11 |
2009-02-11 |
Cgi Pharmaceuticals Inc |
Determinadas amidas sustituidas, el uso de las mismas para el tratamiento de enfermedades mediadas por la inhibicion de la actividad de btk y composiciones farmaceuticas que las comprenden.
|
|
AU2007297221B2
(en)
|
2006-09-11 |
2012-11-08 |
Mylan Laboratories Limited |
Dibenzofuran derivatives as inhibitors of PDE-4 and PDE-10
|
|
WO2008033858A2
(en)
|
2006-09-11 |
2008-03-20 |
Cgi Pharmaceuticals, Inc. |
Kinase inhibitors, and methods of using and identifying kinase inhibitors
|
|
AR063707A1
(es)
|
2006-09-11 |
2009-02-11 |
Cgi Pharmaceuticals Inc |
Determinadas amidas sustituidas, el uso de las mismas para el tratamiento de enfermedades mediadas por la inhibicion de la actividad de btk y composiciones farmacéuticas que las comprenden.
|
|
FR2906250B1
(fr)
|
2006-09-22 |
2008-10-31 |
Sanofi Aventis Sa |
Derives de 2-aryl-6phenyl-imidazo(1,2-a) pyridines, leur preparation et leur application en therapeutique
|
|
WO2008057254A2
(en)
|
2006-10-27 |
2008-05-15 |
Wyeth |
Tricyclic compounds as matrix metalloproteinase inhibitors
|
|
US7851489B2
(en)
|
2006-11-08 |
2010-12-14 |
Bristol-Myers Squibb Company |
Pyridinone compounds
|
|
GB0623209D0
(en)
|
2006-11-21 |
2007-01-03 |
F2G Ltd |
Antifungal agents
|
|
WO2008064317A1
(en)
|
2006-11-22 |
2008-05-29 |
University Of Medicine And Dentistry Of New Jersey |
Lipophilic opioid receptor active compounds
|
|
WO2008064318A2
(en)
|
2006-11-22 |
2008-05-29 |
University Of Medicine And Dentistry Of New Jersey |
Peripheral opioid receptor active compounds
|
|
WO2008071944A1
(en)
|
2006-12-14 |
2008-06-19 |
Boehringer Ingelheim International Gmbh |
Benzoxazoles useful in the treatment of inflammation
|
|
EP2121692B1
(en)
|
2006-12-22 |
2013-04-10 |
Incyte Corporation |
Substituted heterocycles as janus kinase inhibitors
|
|
EP1964840A1
(en)
|
2007-02-28 |
2008-09-03 |
sanofi-aventis |
Imidazo[1,2-a]pyridines and their use as pharmaceuticals
|
|
US8338437B2
(en)
|
2007-02-28 |
2012-12-25 |
Methylgene Inc. |
Amines as small molecule inhibitors
|
|
EP1964841A1
(en)
|
2007-02-28 |
2008-09-03 |
sanofi-aventis |
Imidazo[1,2-a]azine and their use as pharmaceuticals
|
|
JP2008218327A
(ja)
|
2007-03-07 |
2008-09-18 |
Hitachi Ltd |
電解質、電解質膜、それを用いた膜電極接合体、燃料電池電源及び燃料電池電源システム
|
|
JP2010120852A
(ja)
|
2007-03-09 |
2010-06-03 |
Daiichi Sankyo Co Ltd |
新規なジアミド誘導体
|
|
BRPI0809106A2
(pt)
|
2007-03-22 |
2014-08-26 |
Astrazeneca Ab |
Derivados de quinolina para o tratamento de doenças inflamatórias
|
|
EP2147914B1
(en)
|
2007-04-24 |
2014-06-04 |
Shionogi&Co., Ltd. |
Aminodihydrothiazine derivatives substituted with cyclic groups
|
|
EP2151435A4
(en)
|
2007-04-24 |
2011-09-14 |
Shionogi & Co |
PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF ALZHEIMER'S DISEASE
|
|
WO2008134553A1
(en)
|
2007-04-26 |
2008-11-06 |
Xenon Pharmaceuticals Inc. |
Methods of using bicyclic compounds in treating sodium channel-mediated diseases
|
|
CN101855222A
(zh)
|
2007-05-10 |
2010-10-06 |
通用电气健康护理有限公司 |
对大麻素cb2受体具有活性的咪唑并(1,2-a)吡啶和相关化合物
|
|
HRP20131167T1
(hr)
|
2007-06-18 |
2014-01-03 |
Merck Sharp & Dohme B.V. |
Antitijela za humani receptor programirane smrti pd-1
|
|
WO2009027733A1
(en)
|
2007-08-24 |
2009-03-05 |
Astrazeneca Ab |
(2-pyridin-3-ylimidazo[1,2-b]pyridazin-6-yl) urea derivatives as antibacterial agents
|
|
CL2008002793A1
(es)
|
2007-09-20 |
2009-09-04 |
Cgi Pharmaceuticals Inc |
Compuestos derivados de amidas sustituidas, inhibidores de la actividad de btk; composicion farmaceutica que los comprende; utiles en el tratamiento del cancer, trastornos oseos, enfermedades autoinmunes, entre otras
|
|
ES2360929T3
(es)
|
2007-09-20 |
2011-06-10 |
Amgen Inc. |
Derivados del ácido 1-(4-(4-bencilbenzamido)-bencil)azetidin-3-carboxílico y compuestos relacionados como moduladores del receptor s1p para el tratamiento de trastornos inmunitarios.
|
|
DE102007048716A1
(de)
|
2007-10-11 |
2009-04-23 |
Merck Patent Gmbh |
Imidazo[1,2-a]pyrimidinderivate
|
|
TW200932219A
(en)
|
2007-10-24 |
2009-08-01 |
Astellas Pharma Inc |
Oxadiazolidinedione compound
|
|
ATE523508T1
(de)
|
2007-10-25 |
2011-09-15 |
Astrazeneca Ab |
Für die behandlung von zellproliferativen erkrankungen geeignete pyridin- und pyrazinderivate
|
|
US7868001B2
(en)
|
2007-11-02 |
2011-01-11 |
Hutchison Medipharma Enterprises Limited |
Cytokine inhibitors
|
|
WO2009062059A2
(en)
|
2007-11-08 |
2009-05-14 |
Pharmacopeia, Inc. |
Isomeric purinones and 1h-imidazopyridinones as pkc-theta inhibitors
|
|
CA2707491A1
(en)
|
2007-12-13 |
2009-06-18 |
Merck Sharp & Dohme Corp. |
Inhibitors of janus kinases
|
|
RU2364597C1
(ru)
|
2007-12-14 |
2009-08-20 |
Андрей Александрович Иващенко |
ГЕТЕРОЦИКЛИЧЕСКИЕ ИНГИБИТОРЫ Hh-СИГНАЛЬНОГО КАСКАДА, ЛЕКАРСТВЕННЫЕ КОМПОЗИЦИИ НА ИХ ОСНОВЕ И СПОСОБ ЛЕЧЕНИЯ ЗАБОЛЕВАНИЙ, СВЯЗАННЫХ С АББЕРАНТНОЙ АКТИВНОСТЬЮ Hh СИГНАЛЬНОЙ СИСТЕМЫ
|
|
JP2011506514A
(ja)
|
2007-12-19 |
2011-03-03 |
シンジェンタ パーティシペーションズ アクチェンゲゼルシャフト |
殺虫性化合物
|
|
CA2709784A1
(en)
|
2007-12-21 |
2009-07-09 |
University Of Rochester |
Method for altering the lifespan of eukaryotic organisms
|
|
AU2008340182A1
(en)
|
2007-12-21 |
2009-07-02 |
The University Of Sydney |
Translocator protein ligands
|
|
RU2476431C2
(ru)
|
2008-01-18 |
2013-02-27 |
Эйсай Ар Энд Ди Менеджмент Ко., Лтд. |
Конденсированное производное аминодигидротиазина
|
|
JP5381718B2
(ja)
|
2008-01-31 |
2014-01-08 |
コニカミノルタ株式会社 |
ハロ多環芳香族化合物及びその製造方法
|
|
US20110009429A1
(en)
|
2008-02-26 |
2011-01-13 |
Paul Oakley |
Heterocyclic compounds as inhibitors of cxcr2
|
|
EP2095818A1
(en)
|
2008-02-29 |
2009-09-02 |
AEterna Zentaris GmbH |
Use of LHRH antagonists at non-castrating doses
|
|
WO2009114335A2
(en)
|
2008-03-12 |
2009-09-17 |
Merck & Co., Inc. |
Pd-1 binding proteins
|
|
FR2928921B1
(fr)
|
2008-03-21 |
2010-04-23 |
Sanofi Aventis |
Derives polysubstitues de 2-aryl-6-phenyl-imidazo°1,2-a!pyridines, leur preparation et leur application en therapeutique
|
|
FR2928924B1
(fr)
|
2008-03-21 |
2010-04-23 |
Sanofi Aventis |
Derives polysubstitues de 6-heteroaryle-imidazo°1,2-a! pyridines, leur preparation et leur application en therapeutique
|
|
FR2928922B1
(fr)
|
2008-03-21 |
2010-04-23 |
Sanofi Aventis |
Derives de 2-aryl-6-phenyl-imidazo°1,2-a!pyridines polysubstitues, leur preparation et leur application en therapeutique
|
|
EP2271646A1
(en)
|
2008-03-31 |
2011-01-12 |
Takeda Pharmaceutical Company Limited |
Apoptosis signal-regulating kinase 1 inhibitors
|
|
KR101034351B1
(ko)
|
2008-05-14 |
2011-05-16 |
한국화학연구원 |
신규 벤즈옥사졸로 치환된 피리딘 유도체 또는 이의약학적으로 허용가능한 염, 이의 제조방법 및 이를유효성분으로 함유하는 이상세포 성장 질환의 예방 및치료용 약학적 조성물
|
|
CA2724842A1
(en)
|
2008-05-19 |
2009-11-26 |
Sunovion Pharmaceuticals Inc. |
Imidazo[1,2-a]pyridine compounds
|
|
CN102112475A
(zh)
|
2008-05-29 |
2011-06-29 |
西特里斯药业公司 |
作为沉默调节蛋白调节剂的咪唑并吡啶和相关的类似物
|
|
ES2566339T3
(es)
|
2008-06-05 |
2016-04-12 |
Glaxo Group Limited |
Derivados de 4-carboxamida indazol útiles como inhibidores de PI3-quinasas
|
|
US8476430B2
(en)
|
2008-07-24 |
2013-07-02 |
Bristol-Myers Squibb Company |
Fused heterocyclic compounds useful as kinase modulators
|
|
US9643922B2
(en)
|
2008-08-18 |
2017-05-09 |
Yale University |
MIF modulators
|
|
US9540322B2
(en)
|
2008-08-18 |
2017-01-10 |
Yale University |
MIF modulators
|
|
JP2011231017A
(ja)
|
2008-09-09 |
2011-11-17 |
Nissan Chem Ind Ltd |
光学活性エポキシ化合物及び光学活性スルホキシド化合物の製造方法、並びに該方法に用いる配位子、錯体及び該錯体の製造方法
|
|
KR101814408B1
(ko)
|
2008-09-26 |
2018-01-04 |
다나-파버 캔서 인스티튜트 인크. |
인간 항-ｐｄ-１, ｐｄ-ｌ１, 및 ｐｄ-ｌ2 항체 및 그의 용도
|
|
WO2010056875A1
(en)
|
2008-11-12 |
2010-05-20 |
Cgi Pharmaceuticals, Inc. |
Pyridazinones and their use as btk inhibitors
|
|
US20120010188A1
(en)
|
2008-12-04 |
2012-01-12 |
Promimagen Ltd. |
Imidazopyridine Compounds
|
|
AU2009333580B2
(en)
|
2008-12-09 |
2016-07-07 |
Genentech, Inc. |
Anti-PD-L1 antibodies and their use to enhance T-cell function
|
|
US8815840B2
(en)
|
2008-12-19 |
2014-08-26 |
Bristol-Myers Squibb Company |
Carbazole and carboline kinase inhibitors
|
|
JP5487214B2
(ja)
|
2008-12-19 |
2014-05-07 |
ブリストル−マイヤーズ スクイブ カンパニー |
キナーゼ阻害剤として有用なカルバゾールカルボキシアミド化合物
|
|
ES2539620T3
(es)
|
2008-12-19 |
2015-07-02 |
Cephalon, Inc. |
Pirrolotriazina como inhibidor de ALK y de JAK2
|
|
JP5624275B2
(ja)
|
2008-12-22 |
2014-11-12 |
ユー・ディー・シー アイルランド リミテッド |
有機電界発光素子
|
|
CA2740193A1
(en)
|
2008-12-23 |
2010-07-01 |
Abbott Laboratories |
Anti-viral compounds
|
|
JP5578490B2
(ja)
|
2008-12-26 |
2014-08-27 |
味の素株式会社 |
ピラゾロピリミジン化合物
|
|
WO2010089411A2
(en)
|
2009-02-09 |
2010-08-12 |
Universite De La Mediterranee |
Pd-1 antibodies and pd-l1 antibodies and uses thereof
|
|
JP2010202530A
(ja)
|
2009-02-27 |
2010-09-16 |
Tokyo Institute Of Technology |
含ヘテロ芳香族化合物および光学材料
|
|
WO2010104307A2
(ko)
|
2009-03-07 |
2010-09-16 |
주식회사 메디젠텍 |
세포핵에서 세포질로의 ｇｓｋ３의 이동을 억제하는 화합물을 함유하는 세포핵에서 세포질로의 gsk3 이동에 의해 발생되는 질환의 치료 또는 예방용 약학적 조성물
|
|
WO2010115736A2
(en)
|
2009-04-02 |
2010-10-14 |
Merck Serono S.A. |
Dihydroorotate dehydrogenase inhibitors
|
|
SG175195A1
(en)
|
2009-04-16 |
2011-11-28 |
Ct Nac Investigaciones Oncologicas Cnio |
Imidazopyrazines for use as kinase inhibitors
|
|
US8338441B2
(en)
|
2009-05-15 |
2012-12-25 |
Gilead Sciences, Inc. |
Inhibitors of human immunodeficiency virus replication
|
|
KR20120049852A
(ko)
|
2009-06-30 |
2012-05-17 |
시가 테크놀로지스, 인크. |
뎅기 바이러스 감염의 치료 및 예방
|
|
US8993604B2
(en)
|
2009-06-30 |
2015-03-31 |
Siga Technologies, Inc. |
Treatment and prevention of dengue virus infections
|
|
TWI491606B
(zh)
|
2009-07-13 |
2015-07-11 |
Gilead Sciences Inc |
調節細胞凋亡信號之激酶的抑制劑
|
|
JP2011057661A
(ja)
|
2009-08-14 |
2011-03-24 |
Bayer Cropscience Ag |
殺虫性カルボキサミド類
|
|
UA108363C2
(uk)
|
2009-10-08 |
2015-04-27 |
|
Похідні імінотіадіазиндіоксиду як інгібітори bace, композиція на їх основі і їх застосування
|
|
WO2011047129A1
(en)
|
2009-10-15 |
2011-04-21 |
Southern Research Institute |
Treatment of neurodegenerative diseases, causation of memory enhancement, and assay for screening compounds for such
|
|
EA201270566A1
(ru)
|
2009-10-16 |
2012-11-30 |
Риб-Экс Фармасьютикалз, Инк. |
Противомикробные соединения и способы их получения и применения
|
|
WO2011050245A1
(en)
|
2009-10-23 |
2011-04-28 |
Yangbo Feng |
Bicyclic heteroaryls as kinase inhibitors
|
|
WO2011066342A2
(en)
|
2009-11-24 |
2011-06-03 |
Amplimmune, Inc. |
Simultaneous inhibition of pd-l1/pd-l2
|
|
WO2011078221A1
(ja)
|
2009-12-24 |
2011-06-30 |
味の素株式会社 |
イミダゾピリダジン化合物
|
|
WO2011082400A2
(en)
|
2010-01-04 |
2011-07-07 |
President And Fellows Of Harvard College |
Modulators of immunoinhibitory receptor pd-1, and methods of use thereof
|
|
WO2011097607A1
(en)
|
2010-02-08 |
2011-08-11 |
Southern Research Institute |
Anti-viral treatment and assay to screen for anti-viral agent
|
|
AR080433A1
(es)
|
2010-03-02 |
2012-04-11 |
Merck Sharp & Dohme |
Derivados de benzofurancarboxamidas utiles para tratar o prevenir infecciones por vhc y composiciones farmaceuticas que los contienen.
|
|
AU2011223969B2
(en)
|
2010-03-04 |
2015-06-11 |
Merck Sharp & Dohme Llc |
Inhibitors of catechol O-methyl transferase and their use in the treatment of psychotic disorders
|
|
SG184073A1
(en)
|
2010-03-18 |
2012-10-30 |
Pasteur Institut Korea |
Anti-infective compounds
|
|
US8410117B2
(en)
|
2010-03-26 |
2013-04-02 |
Hoffmann-La Roche Inc. |
Imidazopyrimidine derivatives
|
|
US8685969B2
(en)
|
2010-06-16 |
2014-04-01 |
Bristol-Myers Squibb Company |
Carboline carboxamide compounds useful as kinase inhibitors
|
|
JP2013532153A
(ja)
|
2010-06-18 |
2013-08-15 |
ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッド |
慢性免疫病に対する免疫治療のためのｔｉｍ−３およびｐｄ−１に対する二重特異性抗体
|
|
CN102295642B
(zh)
|
2010-06-25 |
2016-04-06 |
中国人民解放军军事医学科学院毒物药物研究所 |
2-芳基咪唑并[1,2-a]吡啶-3-乙酰胺衍生物、其制备方法及用途
|
|
US8907053B2
(en)
|
2010-06-25 |
2014-12-09 |
Aurigene Discovery Technologies Limited |
Immunosuppression modulating compounds
|
|
EP2402345A1
(en)
|
2010-06-29 |
2012-01-04 |
Basf Se |
Pyrazole fused bicyclic compounds
|
|
CN101891895B
(zh)
|
2010-07-28 |
2011-11-30 |
南京航空航天大学 |
基于桥联双水杨醛结构的苯并噻唑类金属配位聚合物及其制法及应用
|
|
WO2012016133A2
(en)
|
2010-07-29 |
2012-02-02 |
President And Fellows Of Harvard College |
Ros1 kinase inhibitors for the treatment of glioblastoma and other p53-deficient cancers
|
|
US8633200B2
(en)
|
2010-09-08 |
2014-01-21 |
Bristol-Myers Squibb Company |
Inhibitors of human immunodeficiency virus replication
|
|
CN101993415B
(zh)
|
2010-09-15 |
2013-08-14 |
北京韩美药品有限公司 |
作为Hedgehog通路抑制剂的化合物以及包含该化合物的药物组合物及其应用
|
|
WO2012047856A2
(en)
|
2010-10-04 |
2012-04-12 |
Institute For Hepatitis And Virus Research |
Novel inhibitors of secretion of hepatitis b virus antigens
|
|
WO2012052745A1
(en)
|
2010-10-21 |
2012-04-26 |
Centro Nacional De Investigaciones Oncológicas (Cnio) |
Combinations of pi3k inhibitors with a second anti -tumor agent
|
|
EP2444084A1
(en)
|
2010-10-21 |
2012-04-25 |
Centro Nacional de Investigaciones Oncológicas (CNIO) |
Use of PI3K inibitors for the treatment of obesity
|
|
CN103282034A
(zh)
|
2010-11-18 |
2013-09-04 |
利亘制药公司 |
造血生长因子模拟物的用途
|
|
UY33808A
(es)
|
2010-12-17 |
2012-07-31 |
Syngenta Participations Ag |
Compuestos insecticidas
|
|
TWI617559B
(zh)
|
2010-12-22 |
2018-03-11 |
江蘇恆瑞醫藥股份有限公司 |
２－芳基咪唑并［１，２－ｂ］嗒．２－苯基咪唑并［１，２－ａ］吡啶，和２－苯基咪唑并［１，２－ａ］吡衍生物
|
|
EP2661433B1
(en)
|
2011-01-04 |
2017-08-16 |
Novartis AG |
Indole compounds or analogues thereof useful for the treatment of age-related macular degeneration (amd)
|
|
WO2012100342A1
(en)
|
2011-01-27 |
2012-08-02 |
Université de Montréal |
Pyrazolopyridine and pyrazolopyrimidine derivatives as melanocortin-4 receptor modulators
|
|
US8921368B2
(en)
|
2011-03-17 |
2014-12-30 |
Bristol-Myers Squibb Company |
Pyrrolopyridazine JAK3 inhibitors and their use for the treatment of inflammatory and autoimmune diseases
|
|
WO2012129562A2
(en)
|
2011-03-24 |
2012-09-27 |
The Scripps Research Institute |
Compounds and methods for inducing chondrogenesis
|
|
JP2014514302A
(ja)
|
2011-04-13 |
2014-06-19 |
メルク・シャープ・アンド・ドーム・コーポレーション |
Ｂａｃｅ阻害薬としての５−置換されたイミノチアジン類およびそれのモノおよびジオキシド、組成物およびそれらの使用
|
|
CN102796103A
(zh)
|
2011-05-23 |
2012-11-28 |
南京英派药业有限公司 |
6-（芳基甲酰）咪唑并[1,2-a]嘧啶和6-（芳基甲酰）[1,2,4]三唑并[4,3-a]嘧啶作为Hedgehog抑制剂及其应用
|
|
JP6007417B2
(ja)
|
2011-05-31 |
2016-10-12 |
レセプトス エルエルシー |
新規ｇｌｐ−１受容体安定剤および調節剤
|
|
GB201109763D0
(en)
|
2011-06-10 |
2011-07-27 |
Ucl Business Plc |
Compounds
|
|
WO2012175991A1
(en)
|
2011-06-24 |
2012-12-27 |
Pharminox Limited |
Fused pentacyclic anti - proliferative compounds
|
|
KR20140058543A
(ko)
|
2011-07-08 |
2014-05-14 |
노파르티스 아게 |
신규 피롤로 피리미딘 유도체
|
|
EP2548877A1
(en)
|
2011-07-19 |
2013-01-23 |
MSD Oss B.V. |
4-(5-Membered fused pyridinyl)benzamides as BTK-inhibitors
|
|
WO2013033901A1
(en)
|
2011-09-08 |
2013-03-14 |
Merck Sharp & Dohme Corp. |
Heterocyclic-substituted benzofuran derivatives and methods of use thereof for the treatment of viral diseases
|
|
WO2013040528A1
(en)
|
2011-09-16 |
2013-03-21 |
Microbiotix, Inc. |
Antimicrobial compounds
|
|
EP2757884B1
(en)
|
2011-09-22 |
2022-07-27 |
Merck Sharp & Dohme LLC |
Pyrazolopyridyl compounds as aldosterone synthase inhibitors
|
|
JP6040677B2
(ja)
|
2011-09-29 |
2016-12-07 |
東洋インキＳｃホールディングス株式会社 |
太陽電池封止材用樹脂組成物
|
|
CA2851445A1
(en)
|
2011-10-13 |
2013-04-18 |
Novartis Ag |
Novel oxazine derivatives and their use in the treatment of disease
|
|
RU2014120180A
(ru)
|
2011-10-20 |
2015-11-27 |
ГЛЭКСОСМИТКЛАЙН ЭлЭлСи |
Замещенные бициклические аза-гетероциклы и аналоги в качестве модуляторов сиртуина
|
|
SG11201401359SA
(en)
|
2011-10-21 |
2014-05-29 |
Torrent Pharmaceuticals Ltd |
Novel substituted imidazopyrimidines as gpbar1 receptor modulators
|
|
WO2013120040A1
(en)
|
2012-02-10 |
2013-08-15 |
Children's Medical Center Corporation |
Targeted pathway inhibition to improve muscle structure, function and activity in muscular dystrophy
|
|
US9034882B2
(en)
|
2012-03-05 |
2015-05-19 |
Bristol-Myers Squibb Company |
Inhibitors of human immunodeficiency virus replication
|
|
WO2013133367A1
(ja)
|
2012-03-09 |
2013-09-12 |
カルナバイオサイエンス株式会社 |
新規トリアジン誘導体
|
|
PL2825042T3
(pl)
|
2012-03-15 |
2019-02-28 |
Celgene Car Llc |
Sole inhibitora kinazy receptora czynnika wzrostu naskórka
|
|
ES2571479T3
(es)
|
2012-04-20 |
2016-05-25 |
Gilead Sciences Inc |
Derivados del ácido benzotiazol-6-il acético y su uso para tratar una infección por VIH
|
|
WO2013157021A1
(en)
|
2012-04-20 |
2013-10-24 |
Advinus Therapeutics Limited |
Bicyclic compounds, compositions and medicinal applications thereof
|
|
WO2013163404A1
(en)
|
2012-04-27 |
2013-10-31 |
The Uab Research Foundation |
TREATING VIRAL INFECTIONS HAVING VIRAL RNAs TRANSLATED BY A NON-IRES MEDIATED MECHANISM
|
|
EP2862853B1
(en)
|
2012-06-18 |
2020-01-22 |
Sumitomo Chemical Co., Ltd |
Fused heterocyclic compound
|
|
WO2014007228A1
(ja)
|
2012-07-03 |
2014-01-09 |
小野薬品工業株式会社 |
ソマトスタチン受容体作動活性を有する化合物およびその医薬用途
|
|
GB201212513D0
(en)
|
2012-07-13 |
2012-08-29 |
Ucb Pharma Sa |
Therapeutic agents
|
|
CN104619709B
(zh)
|
2012-07-13 |
2016-11-09 |
Ucb生物制药私人有限公司 |
作为tnf活性调节剂的咪唑并吡啶衍生物
|
|
JP2015178457A
(ja)
|
2012-07-25 |
2015-10-08 |
杏林製薬株式会社 |
ピラゾロピリジン誘導体、またはその薬理学的に許容される塩
|
|
ES2666353T3
(es)
|
2012-09-06 |
2018-05-04 |
Bristol-Myers Squibb Company |
Inhibidores de JAK3 de imidazopiridazina y su uso para el tratamiento de enfermedades inflamatorias y autoinmunitarias
|
|
DK2900657T3
(da)
|
2012-09-26 |
2020-05-04 |
Hoffmann La Roche |
Cykliske etherpyrazol-4-yl-heterocyclyl-carboxamidforbindelser og fremgangsmåder til anvendelse
|
|
WO2014061693A1
(ja)
|
2012-10-17 |
2014-04-24 |
塩野義製薬株式会社 |
新規非芳香族炭素環又は非芳香族複素環誘導体
|
|
US9163027B2
(en)
|
2012-11-21 |
2015-10-20 |
Stategics, Inc. |
Substituted triazolo-pyrimidine compounds for modulating cell proliferation differentiation and survival
|
|
JP6037804B2
(ja)
|
2012-12-03 |
2016-12-07 |
富士フイルム株式会社 |
ガス分離膜
|
|
RS60244B1
(sr)
|
2013-01-15 |
2020-06-30 |
Incyte Holdings Corp |
Jedinjenja tiazolkarboksamida i piridinkarboksamida korisna kao inhibitori pim kinaze
|
|
CN104968660A
(zh)
|
2013-01-22 |
2015-10-07 |
霍夫曼-拉罗奇有限公司 |
作为bace1抑制剂的氟-[1,3]噁嗪类化合物
|
|
CN103933036B
(zh)
|
2013-01-23 |
2017-10-13 |
中国人民解放军军事医学科学院毒物药物研究所 |
2‑芳基咪唑并[1,2‑α]吡啶‑3‑乙酰胺衍生物在制备防治PTSD的药物中的用途
|
|
EP2950814A4
(en)
|
2013-01-31 |
2016-06-08 |
Univ Jefferson |
FUSION PROTEINS BASED ON PD-L1 AND PD-L2 AND USES THEREOF
|
|
KR102169426B1
(ko)
|
2013-02-27 |
2020-10-23 |
모찌다 세이야쿠 가부시끼가이샤 |
신규 피라졸 유도체
|
|
AP2015008716A0
(en)
|
2013-03-08 |
2015-09-30 |
Amgen Inc |
Perfluorinated cyclopropyl fused 1,3-oxazin-2-amine compounds as beta-secretase inhibitors and methods of use
|
|
CN104045552B
(zh)
|
2013-03-13 |
2019-06-11 |
江苏先声药业有限公司 |
作为神经保护剂的药用化合物
|
|
JP2016516399A
(ja)
|
2013-03-13 |
2016-06-09 |
オーストラリアン ニュークリア サイエンス アンド テクノロジー オーガニゼーション |
非機能性ｔｓｐｏ遺伝子を有するトランスジェニック非ヒト生物
|
|
US9527842B2
(en)
|
2013-03-14 |
2016-12-27 |
VIIV Healthcare UK (No.5) Limited |
Inhibitors of human immunodeficiency virus replication
|
|
EP2968304B1
(en)
|
2013-03-14 |
2018-10-10 |
The Trustees of Columbia University in the City of New York |
4-phenylpiperidines, their preparation and use
|
|
WO2014152536A2
(en)
|
2013-03-14 |
2014-09-25 |
Celtaxsys, Inc. |
Inhibitors of leukotriene a4 hydrolase
|
|
CN105209449B
(zh)
|
2013-03-14 |
2019-02-01 |
库拉德夫制药私人有限公司 |
犬尿氨酸途径的抑制剂
|
|
SG11201506687RA
(en)
|
2013-03-15 |
2015-09-29 |
Plexxikon Inc |
Heterocyclic compounds and uses thereof
|
|
US9308236B2
(en)
|
2013-03-15 |
2016-04-12 |
Bristol-Myers Squibb Company |
Macrocyclic inhibitors of the PD-1/PD-L1 and CD80(B7-1)/PD-L1 protein/protein interactions
|
|
WO2014181287A1
(en)
|
2013-05-09 |
2014-11-13 |
Piramal Enterprises Limited |
Heterocyclyl compounds and uses thereof
|
|
JP6509838B2
(ja)
|
2013-06-26 |
2019-05-08 |
アッヴィ・インコーポレイテッド |
Ｂｔｋ阻害薬としての一級カルボキサミド類
|
|
WO2015000715A1
(en)
|
2013-07-02 |
2015-01-08 |
Syngenta Participations Ag |
Pesticidally active bi- or tricyclic heterocycles with sulfur containing substituents
|
|
HK1222658A1
(zh)
|
2013-07-17 |
2017-07-07 |
Otsuka Pharmaceutical Co., Ltd. |
氰基三唑化合物
|
|
AU2014292888B2
(en)
|
2013-07-25 |
2018-03-22 |
Dana-Farber Cancer Institute, Inc. |
Inhibitors of transcription factors and uses thereof
|
|
EP2835375A1
(en)
|
2013-08-09 |
2015-02-11 |
Fundació Institut Català d'Investigació Química |
Bis-salphen compounds and carbonaceous material composites comprising them
|
|
KR101715090B1
(ko)
|
2013-08-28 |
2017-03-13 |
한국화학연구원 |
신규한 화합물 또는 이의 약학적으로 허용가능한 염, 및 이를 유효성분으로 함유하는 인플루엔자 바이러스 감염으로 인한 질환의 예방 또는 치료용 약학적 조성물
|
|
JP6417419B2
(ja)
|
2013-09-04 |
2018-11-07 |
ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ |
免疫調節剤として有用な化合物
|
|
SI3041828T1
(sl)
|
2013-09-06 |
2018-10-30 |
Aurigene Discovery Technologies Limited |
1,3,4-oksadiazolni in 1,3,4-tiadiazolni derivati kot imunomodulatorji
|
|
HRP20181052T1
(hr)
|
2013-09-06 |
2018-09-07 |
Aurigene Discovery Technologies Limited |
Derivati 1,2,4-oksadiazola kao imunomodulatori
|
|
WO2015036927A1
(en)
|
2013-09-10 |
2015-03-19 |
Aurigene Discovery Technologies Limited |
Immunomodulating peptidomimetic derivatives
|
|
JP6336870B2
(ja)
|
2013-09-30 |
2018-06-06 |
日本ポリプロ株式会社 |
ビフェノール化合物及びそれを用いるオレフィン重合用触媒並びにオレフィン重合体の製造方法
|
|
GB201321746D0
(en)
|
2013-12-09 |
2014-01-22 |
Ucb Pharma Sa |
Therapeutic agents
|
|
GB201321743D0
(en)
|
2013-12-09 |
2014-01-22 |
Ucb Pharma Sa |
Therapeutic agents
|
|
GB201321736D0
(en)
|
2013-12-09 |
2014-01-22 |
Ucb Pharma Sa |
Therapeutic agents
|
|
GB201321733D0
(en)
|
2013-12-09 |
2014-01-22 |
Ucb Pharma Sa |
Therapeutic agents
|
|
WO2015095337A2
(en)
|
2013-12-18 |
2015-06-25 |
The Rockefeller University |
PYRAZOLO[1,5-a]PYRIMIDINECARBOXAMIDE DERIVATIVES FOR TREATING COGNITIVE IMPAIRMENT
|
|
AU2014375265B2
(en)
|
2014-01-03 |
2018-11-01 |
Elanco Animal Health Gmbh |
Novel pyrazolyl-heteroarylamides as pesticides
|
|
US20160356794A1
(en)
|
2014-02-10 |
2016-12-08 |
Merck Sharp & Dohme Corp. |
Antibodies that bind to human tau and assay for quantifying human tau using the antibodies
|
|
HRP20200182T1
(hr)
|
2014-02-25 |
2020-05-01 |
Achillion Pharmaceuticals, Inc. |
Aril, heteroaril i heterociklični spojevi za liječenje komplementom posredovanih poremećaja
|
|
US9394365B1
(en)
|
2014-03-12 |
2016-07-19 |
Yeda Research And Development Co., Ltd |
Reducing systemic regulatory T cell levels or activity for treatment of alzheimer's disease
|
|
JP6490464B2
(ja)
|
2014-03-26 |
2019-03-27 |
三井化学株式会社 |
遷移金属化合物、オレフィン重合用触媒およびオレフィン系重合体の製造方法
|
|
NZ725860A
(en)
|
2014-04-04 |
2019-08-30 |
Iomet Pharma Ltd |
Indole derivatives for use in medicine
|
|
US9850225B2
(en)
|
2014-04-14 |
2017-12-26 |
Bristol-Myers Squibb Company |
Compounds useful as immunomodulators
|
|
KR20170005853A
(ko)
|
2014-05-14 |
2017-01-16 |
프레지던트 앤드 펠로우즈 오브 하바드 칼리지 |
유기 발광 다이오드 물질
|
|
WO2015197028A1
(en)
|
2014-06-28 |
2015-12-30 |
Sunshine Lake Pharma Co., Ltd. |
Compounds as hepatitis c virus (hcv) inhibitors and uses thereof in medicine
|
|
CN104211726B
(zh)
|
2014-08-11 |
2017-06-16 |
中南民族大学 |
非茂类三齿双核钛配合物、制备方法及用途
|
|
WO2016044604A1
(en)
|
2014-09-17 |
2016-03-24 |
Epizyme, Inc. |
Carm1 inhibitors and uses thereof
|
|
KR20170090408A
(ko)
|
2014-09-19 |
2017-08-07 |
매카이 메디컬 파운데이션 더 프레즈비티리언 처치 인 타이완 매카이 메모리얼 호스피탈 |
벤조-헤테로시클릭 화합물 및 이의 적용
|
|
ES2907622T3
(es)
|
2014-10-06 |
2022-04-25 |
Merck Patent Gmbh |
Compuestos de heteroarilo como inhibidores de BTK y usos de estos
|
|
JP2017537940A
(ja)
|
2014-12-10 |
2017-12-21 |
マサチューセッツ インスティテュート オブ テクノロジー |
増殖性疾患の処置に有用な融合１，３−アゾール誘導体
|
|
JP6853619B2
(ja)
|
2015-01-16 |
2021-03-31 |
大塚製薬株式会社 |
シアノトリアゾール化合物の医薬用途
|
|
DE112016000383A5
(de)
|
2015-01-20 |
2017-10-05 |
Cynora Gmbh |
Organische Moleküle, insbesondere zur Verwendung in optoelektronischen Bauelementen
|
|
EP3261442B1
(en)
|
2015-01-20 |
2020-04-01 |
Merck Sharp & Dohme Corp. |
Iminothiadiazine dioxides bearing an amine-linked substituent as bace inhibitors, compositions, and their use
|
|
WO2016156282A1
(en)
|
2015-04-02 |
2016-10-06 |
Bayer Cropscience Aktiengesellschaft |
Novel triazole compounds for controlling phytopathogenic harmful fungi
|
|
WO2017035405A1
(en)
|
2015-08-26 |
2017-03-02 |
Achillion Pharmaceuticals, Inc. |
Amino compounds for treatment of immune and inflammatory disorders
|
|
US10745382B2
(en)
|
2015-10-15 |
2020-08-18 |
Bristol-Myers Squibb Company |
Compounds useful as immunomodulators
|
|
EP3365340B1
(en)
|
2015-10-19 |
2022-08-10 |
Incyte Corporation |
Heterocyclic compounds as immunomodulators
|
|
US10633370B2
(en)
|
2015-10-21 |
2020-04-28 |
University of Pittsburgh—of the Commonwealth System of Higher Education |
Phenyl indole allosteric inhibitors of p97 ATPase
|
|
US9603950B1
(en)
|
2015-10-25 |
2017-03-28 |
Institute Of Nuclear Energy Research |
Compounds of imaging agent with HDAC inhibitor for treatment of Alzheimer syndrome and method of synthesis thereof
|
|
KR101717601B1
(ko)
|
2015-11-10 |
2017-03-20 |
한국화학연구원 |
신규한 화합물 또는 이의 약학적으로 허용가능한 염, 및 이를 유효성분으로 함유하는 인플루엔자 바이러스 감염으로 인한 질환의 예방 또는 치료용 약학적 조성물
|
|
US20170145025A1
(en)
|
2015-11-19 |
2017-05-25 |
Incyte Corporation |
Heterocyclic compounds as immunomodulators
|
|
ES2916874T3
(es)
|
2015-12-17 |
2022-07-06 |
Incyte Corp |
Derivados de N-fenil-piridina-2-carboxamida y su uso como moduladores de la interacción proteína/proteína PD-1/PD-L1
|
|
AU2016379372A1
(en)
|
2015-12-22 |
2018-08-02 |
Incyte Corporation |
Heterocyclic compounds as immunomodulators
|
|
JP6943857B2
(ja)
|
2015-12-22 |
2021-10-06 |
シンジェンタ パーティシペーションズ アーゲー |
有害生物防除活性ピラゾール誘導体
|
|
HRP20210698T1
(hr)
|
2015-12-22 |
2021-09-17 |
Immatics Biotechnologies Gmbh |
Peptidi i kombinacija peptida za uporabu u imunoterapiji protiv karcinoma dojke i drugih karcinoma
|
|
WO2017109041A1
(en)
|
2015-12-22 |
2017-06-29 |
Synthon B.V. |
Pharmaceutical composition comprising amorphous lenalidomide and an antioxidant
|
|
WO2017107052A1
(en)
|
2015-12-22 |
2017-06-29 |
Merck Sharp & Dohme Corp. |
Soluble guanylate cyclase stimulators
|
|
KR101653560B1
(ko)
|
2016-02-02 |
2016-09-12 |
한국화학연구원 |
신규한 화합물 또는 이의 약학적으로 허용가능한 염, 및 이를 유효성분으로 함유하는 인플루엔자 바이러스 감염으로 인한 질환의 예방 또는 치료용 약학적 조성물
|
|
JP6999574B2
(ja)
|
2016-04-22 |
2022-01-18 |
インサイト・コーポレイション |
Ｌｓｄ１阻害剤の製剤
|
|
ES2906460T3
(es)
|
2016-05-06 |
2022-04-18 |
Incyte Corp |
Compuestos heterocíclicos como inmunomoduladores
|
|
ES2905980T3
(es)
|
2016-05-26 |
2022-04-12 |
Incyte Corp |
Compuestos heterocíclicos como inmunomoduladores
|
|
JP7042812B2
(ja)
|
2016-06-20 |
2022-03-28 |
ノバルティス アーゲー |
トリアゾロピリミジン化合物の結晶形態
|
|
KR102518451B1
(ko)
|
2016-06-20 |
2023-04-04 |
엘랑코 유에스 인코포레이티드 |
Peg화된 돼지 인터페론 및 그의 사용 방법
|
|
BR112018076534A2
(pt)
|
2016-06-20 |
2019-04-02 |
Incyte Corporation |
compostos heterocíclicos como imunomoduladores
|
|
ES2870920T3
(es)
|
2016-06-21 |
2021-10-28 |
X4 Pharmaceuticals Inc |
Inhibidores de CXCR4 y usos de los mismos
|
|
MA45669A
(fr)
|
2016-07-14 |
2019-05-22 |
Incyte Corp |
Composés hétérocycliques utilisés comme immunomodulateurs
|
|
AU2017305399A1
(en)
|
2016-08-03 |
2019-01-31 |
Arising International, Inc. |
Symmetric or semi-symmetric compounds useful as immunomodulators
|
|
ES2941716T3
(es)
|
2016-08-29 |
2023-05-25 |
Incyte Corp |
Compuestos heterocíclicos como inmunomoduladores
|
|
IL264878B
(en)
|
2016-08-30 |
2022-06-01 |
Tetraphase Pharmaceuticals Inc |
Tetracycline compounds and methods of treatment
|
|
ES2856248T3
(es)
|
2016-12-21 |
2021-09-27 |
Acerta Pharma Bv |
Inhibidores de imidazopirazina de la tirosina quinasa de Bruton
|
|
TWI795381B
(zh)
|
2016-12-21 |
2023-03-11 |
比利時商健生藥品公司 |
作為ｍａｌｔ１抑制劑之吡唑衍生物
|
|
SMT202100573T1
(it)
|
2016-12-22 |
2021-11-12 |
Calithera Biosciences Inc |
Composizioni e metodi per l'inibizione dell'attivita' dell'arginasi
|
|
AU2017382870B2
(en)
|
2016-12-22 |
2022-03-24 |
Incyte Corporation |
Benzooxazole derivatives as immunomodulators
|
|
ES2899402T3
(es)
|
2016-12-22 |
2022-03-11 |
Incyte Corp |
Derivados de piridina como inmunomoduladores
|
|
EP3558990B1
(en)
|
2016-12-22 |
2022-08-10 |
Incyte Corporation |
Tetrahydro imidazo[4,5-c]pyridine derivatives as pd-l1 internalization inducers
|
|
ES2874756T3
(es)
|
2016-12-22 |
2021-11-05 |
Incyte Corp |
Derivados de triazolo[1,5-A]piridina como inmunomoduladores
|
|
WO2018119263A1
(en)
|
2016-12-22 |
2018-06-28 |
Incyte Corporation |
Heterocyclic compounds derivatives as pd-l1 internalization inducers
|
|
WO2018119286A1
(en)
|
2016-12-22 |
2018-06-28 |
Incyte Corporation |
Bicyclic heteroaromatic compounds as immunomodulators
|
|
JOP20190239A1
(ar)
|
2017-04-19 |
2019-10-09 |
Neurocrine Biosciences Inc |
مركبات مثبطة لـ vmat2 وتركيبات منها
|
|
BR102018007822A2
(pt)
|
2017-04-20 |
2018-11-06 |
Gilead Sciences, Inc. |
composto, métodos para inibir pd-1, pd-l1 e/ou interação de pd-1/pd-l1 e para tratamento de câncer, composição farmacêutica, e, kit para tratamento de ou prevenção de câncer ou uma doença ou condição
|
|
AU2018306619B2
(en)
|
2017-07-28 |
2022-06-02 |
Chemocentryx, Inc. |
Immunomodulator compounds
|
|
CN111225665B
(zh)
|
2017-08-08 |
2023-12-08 |
凯莫森特里克斯股份有限公司 |
大环免疫调节剂
|
|
WO2019034172A1
(zh)
|
2017-08-18 |
2019-02-21 |
上海轶诺药业有限公司 |
一种具有pd-l1抑制活性的化合物、其制备方法及用途
|
|
TWI707849B
(zh)
|
2018-02-13 |
2020-10-21 |
美商基利科學股份有限公司 |
Pd‐1/pd‐l1抑制劑
|
|
CR20200520A
(es)
|
2018-03-30 |
2021-03-09 |
Incyte Corp |
Compuestos heterocíclicos como inmunomoduladores
|
|
WO2019192506A1
(en)
|
2018-04-03 |
2019-10-10 |
Betta Pharmaceuticals Co., Ltd |
Immunomodulators, compositions and methods thereof
|
|
KR102591947B1
(ko)
|
2018-04-19 |
2023-10-25 |
길리애드 사이언시즈, 인코포레이티드 |
Pd-1/pd-l1 억제제
|
|
WO2019217821A1
(en)
|
2018-05-11 |
2019-11-14 |
Incyte Corporation |
Tetrahydro-imidazo[4,5-c]pyridine derivatives as pd-l1 immunomodulators
|
|
CA3109211A1
(en)
|
2018-08-15 |
2020-02-20 |
Moonshine Solutions As |
Method and device for supplying liquid to a liner
|
|
US11236085B2
(en)
|
2018-10-24 |
2022-02-01 |
Gilead Sciences, Inc. |
PD-1/PD-L1 inhibitors
|
|
KR20210089195A
(ko)
|
2018-11-02 |
2021-07-15 |
상하이 맥시노벨 파마수티컬스 씨오., 엘티디. |
비페닐계 화합물, 이의 중간체, 제조 방법, 약학 조성물 및 용도
|
|
US11596692B1
(en)
|
2018-11-21 |
2023-03-07 |
Incyte Corporation |
PD-L1/STING conjugates and methods of use
|
|
EP3917927A4
(en)
|
2019-01-31 |
2022-10-26 |
Betta Pharmaceuticals Co., Ltd |
IMMUNE MODULATORS, COMPOSITIONS AND METHODS THEREOF
|
|
GB201911210D0
(en)
|
2019-08-06 |
2019-09-18 |
Amlo Biosciences Ltd |
Clinical management of oropharyngeal squamous cell carcinoma
|
|
EP4010342A1
(en)
|
2019-08-09 |
2022-06-15 |
Incyte Corporation |
Salts of a pd-1/pd-l1 inhibitor
|
|
JP7732977B2
(ja)
|
2019-09-20 |
2025-09-02 |
トランスジーン |
Ｈｐｖポリペプチドおよびｉｌ－２をコードするポックスウイルスと抗ｐｄ－ｌ１抗体の組合せ
|
|
WO2021067217A1
(en)
|
2019-09-30 |
2021-04-08 |
Incyte Corporation |
Pyrido[3,2-d]pyrimidine compounds as immunomodulators
|
|
BR112022009031A2
(pt)
|
2019-11-11 |
2022-10-11 |
Incyte Corp |
Sais e formas cristalinas de um inibidor de pd-1/pd-l1
|
|
KR20230006568A
(ko)
|
2020-05-04 |
2023-01-10 |
비욘드스프링 파마수티컬스, 인코포레이티드. |
낮은 면역원성을 갖는 암에서 암세포 사멸을 강화하기 위한 삼중 병용 요법
|
|
WO2022099075A1
(en)
|
2020-11-06 |
2022-05-12 |
Incyte Corporation |
Crystalline form of a pd-1/pd-l1 inhibitor
|
|
US11780836B2
(en)
|
2020-11-06 |
2023-10-10 |
Incyte Corporation |
Process of preparing a PD-1/PD-L1 inhibitor
|
|
US11866434B2
(en)
|
2020-11-06 |
2024-01-09 |
Incyte Corporation |
Process for making a PD-1/PD-L1 inhibitor and salts and crystalline forms thereof
|
|
TW202241420A
(zh)
|
2020-12-18 |
2022-11-01 |
美商英塞特公司 |
Ｐｄ－ｌ１抑制劑之口服調配物
|
|
US20230149409A1
(en)
|
2021-09-24 |
2023-05-18 |
Incyte Corporation |
Treatment of human papillomavirus-associated cancers by pd-l1 inhibitors
|