ATE301653T1 - Pyrazolopyridine - Google Patents

Pyrazolopyridine

Info

Publication number
ATE301653T1
ATE301653T1 AT01987095T AT01987095T ATE301653T1 AT E301653 T1 ATE301653 T1 AT E301653T1 AT 01987095 T AT01987095 T AT 01987095T AT 01987095 T AT01987095 T AT 01987095T AT E301653 T1 ATE301653 T1 AT E301653T1
Authority
AT
Austria
Prior art keywords
pyrazolopyridines
same
variables
preparing
processes
Prior art date
Application number
AT01987095T
Other languages
English (en)
Inventor
Stanley D Chamberlain
Kristjan Gudmundsson
Brian A Johns
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of ATE301653T1 publication Critical patent/ATE301653T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT01987095T 2000-12-15 2001-11-26 Pyrazolopyridine ATE301653T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US25576300P 2000-12-15 2000-12-15
US27428401P 2001-03-08 2001-03-08
US31508901P 2001-08-27 2001-08-27
PCT/US2001/044210 WO2002048147A2 (en) 2000-12-15 2001-11-26 Pyrazolopyridines

Publications (1)

Publication Number Publication Date
ATE301653T1 true ATE301653T1 (de) 2005-08-15

Family

ID=27400896

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01987095T ATE301653T1 (de) 2000-12-15 2001-11-26 Pyrazolopyridine

Country Status (8)

Country Link
US (3) US6919352B2 (de)
EP (1) EP1341788B1 (de)
JP (1) JP2004518651A (de)
AT (1) ATE301653T1 (de)
AU (1) AU2002239344A1 (de)
DE (1) DE60112609T2 (de)
ES (1) ES2245380T3 (de)
WO (1) WO2002048147A2 (de)

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DE60112609T2 (de) 2000-12-15 2006-01-19 Glaxo Group Ltd., Greenford Pyrazolopyridine
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US7807673B2 (en) * 2005-12-05 2010-10-05 Glaxosmithkline Llc 2-pyrimidinyl pyrazolopyridine ErbB kinase inhibitors
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RU2541571C2 (ru) 2009-04-15 2015-02-20 Эббви Инк. Противовирусные соединения
CN103649079B (zh) 2010-12-22 2016-11-16 Abbvie公司 丙型肝炎抑制剂及其用途
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US20170107216A1 (en) 2015-10-19 2017-04-20 Incyte Corporation Heterocyclic compounds as immunomodulators
AU2016358100B2 (en) 2015-11-19 2021-05-27 Incyte Corporation Heterocyclic compounds as immunomodulators
TW201726623A (zh) 2015-12-17 2017-08-01 英塞特公司 作為免疫調節劑之雜環化合物
TWI850624B (zh) 2015-12-22 2024-08-01 美商英塞特公司 作為免疫調節劑之雜環化合物
TW201808950A (zh) 2016-05-06 2018-03-16 英塞特公司 作為免疫調節劑之雜環化合物
US20170342060A1 (en) 2016-05-26 2017-11-30 Incyte Corporation Heterocyclic compounds as immunomodulators
DK3472167T3 (da) 2016-06-20 2022-09-05 Incyte Corp Heterocykliske forbindelser som immunomodulatorer
EP3484866B1 (de) 2016-07-14 2022-09-07 Incyte Corporation Heterocyclische verbindungen als immunmodulatoren
EP3504198B1 (de) 2016-08-29 2023-01-25 Incyte Corporation Heterocyclische verbindungen als immunmodulatoren
EP3558973B1 (de) 2016-12-22 2021-09-15 Incyte Corporation Pyridinderivate als immunmodulatoren
ES2929193T3 (es) 2016-12-22 2022-11-25 Incyte Corp Derivados de tetrahidro imidazo[4,5-c]piridina como inductores de la internalización de PD-L1
EP3558963B1 (de) 2016-12-22 2022-03-23 Incyte Corporation Bicyclische heteroaromatische verbindungen als immunmodulatoren
ES2874756T3 (es) 2016-12-22 2021-11-05 Incyte Corp Derivados de triazolo[1,5-A]piridina como inmunomoduladores
IL295660A (en) 2016-12-22 2022-10-01 Incyte Corp Benzooxazole derivatives as immunomodulators
RS64055B1 (sr) 2018-03-30 2023-04-28 Incyte Corp Heterociklična jedinjenja kao imunomodulatori
EP4219492B1 (de) 2018-05-11 2024-11-27 Incyte Corporation Heterocyclische verbindungen als immunmodulatoren
JP7665593B2 (ja) 2019-08-09 2025-04-21 インサイト・コーポレイション Ｐｄ－１／ｐｄ－ｌ１阻害剤の塩
EP4037773A1 (de) 2019-09-30 2022-08-10 Incyte Corporation Pyrido[3,2-d]pyrimidin-verbindungen als immunmodulatoren
BR112022009031A2 (pt) 2019-11-11 2022-10-11 Incyte Corp Sais e formas cristalinas de um inibidor de pd-1/pd-l1
DE102020125641A1 (de) * 2020-09-25 2022-03-31 Creative Therapeutics Gmbh Wirkstoffe und Arzneimittel für die Therapie von Viruserkrankungen, insbesondere Corona-Infektionen, insbesondere COVID-19
WO2022099018A1 (en) 2020-11-06 2022-05-12 Incyte Corporation Process of preparing a pd-1/pd-l1 inhibitor
EP4240739A1 (de) 2020-11-06 2023-09-13 Incyte Corporation Verfahren zur herstellung eines pd-1/pd-l1-inhibitors sowie salze und kristalline formen davon
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Also Published As

Publication number Publication date
US7087618B2 (en) 2006-08-08
ES2245380T3 (es) 2006-01-01
US20050171133A1 (en) 2005-08-04
EP1341788B1 (de) 2005-08-10
DE60112609D1 (en) 2005-09-15
US6919352B2 (en) 2005-07-19
US20050182080A1 (en) 2005-08-18
US7160897B2 (en) 2007-01-09
WO2002048147A2 (en) 2002-06-20
WO2002048147A3 (en) 2003-03-27
JP2004518651A (ja) 2004-06-24
DE60112609T2 (de) 2006-01-19
AU2002239344A1 (en) 2002-06-24
US20040072853A1 (en) 2004-04-15
EP1341788A2 (de) 2003-09-10

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