JP2014060993A5 - - Google Patents
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- JP2014060993A5 JP2014060993A5 JP2013216256A JP2013216256A JP2014060993A5 JP 2014060993 A5 JP2014060993 A5 JP 2014060993A5 JP 2013216256 A JP2013216256 A JP 2013216256A JP 2013216256 A JP2013216256 A JP 2013216256A JP 2014060993 A5 JP2014060993 A5 JP 2014060993A5
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- Prior art keywords
- mir
- gene product
- lung cancer
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- 108090000623 proteins and genes Proteins 0.000 claims 38
- 108091033773 MiR-155 Proteins 0.000 claims 25
- 238000000034 method Methods 0.000 claims 14
- 206010058467 Lung neoplasm malignant Diseases 0.000 claims 11
- 201000005202 lung cancer Diseases 0.000 claims 11
- 208000020816 lung neoplasm Diseases 0.000 claims 11
- 239000000523 sample Substances 0.000 claims 10
- 206010009944 Colon cancer Diseases 0.000 claims 7
- 108091048308 miR-210 stem-loop Proteins 0.000 claims 7
- 108091070501 miRNA Proteins 0.000 claims 7
- 208000001333 Colorectal Neoplasms Diseases 0.000 claims 6
- 108091033433 MiR-191 Proteins 0.000 claims 6
- -1 miR-199a-1 Proteins 0.000 claims 6
- 239000013068 control sample Substances 0.000 claims 4
- 108091029119 miR-34a stem-loop Proteins 0.000 claims 4
- 108091028066 Mir-126 Proteins 0.000 claims 3
- 238000001514 detection method Methods 0.000 claims 3
- 238000009396 hybridization Methods 0.000 claims 3
- 108091035155 miR-10a stem-loop Proteins 0.000 claims 3
- 108091071817 miR-128b stem-loop Proteins 0.000 claims 3
- 108091091751 miR-17 stem-loop Proteins 0.000 claims 3
- 108091044046 miR-17-1 stem-loop Proteins 0.000 claims 3
- 108091065423 miR-17-3 stem-loop Proteins 0.000 claims 3
- 108091062762 miR-21 stem-loop Proteins 0.000 claims 3
- 108091041631 miR-21-1 stem-loop Proteins 0.000 claims 3
- 108091044442 miR-21-2 stem-loop Proteins 0.000 claims 3
- 108091053257 miR-99b stem-loop Proteins 0.000 claims 3
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- 108091028080 MiR-132 Proteins 0.000 claims 2
- 108091028076 Mir-127 Proteins 0.000 claims 2
- 108091080933 Mir-192/215 microRNA precursor Proteins 0.000 claims 2
- 108091062154 Mir-205 Proteins 0.000 claims 2
- 108091034117 Oligonucleotide Proteins 0.000 claims 2
- 108091047626 let-7a-2 stem-loop Proteins 0.000 claims 2
- 108091007427 let-7g Proteins 0.000 claims 2
- 108091023819 miR-124a-1 stem-loop Proteins 0.000 claims 2
- 108091038720 miR-129-1 stem-loop Proteins 0.000 claims 2
- 108091047467 miR-136 stem-loop Proteins 0.000 claims 2
- 108091058688 miR-141 stem-loop Proteins 0.000 claims 2
- 108091089860 miR-148 stem-loop Proteins 0.000 claims 2
- 108091047577 miR-149 stem-loop Proteins 0.000 claims 2
- 108091035696 miR-149-1 stem-loop Proteins 0.000 claims 2
- 108091031096 miR-149-2 stem-loop Proteins 0.000 claims 2
- 108091056204 miR-16-2 stem-loop Proteins 0.000 claims 2
- 108091040170 miR-196-2 stem-loop Proteins 0.000 claims 2
- 108091092012 miR-199b stem-loop Proteins 0.000 claims 2
- 108091089775 miR-200b stem-loop Proteins 0.000 claims 2
- 108091045665 miR-202 stem-loop Proteins 0.000 claims 2
- 108091088730 miR-215 stem-loop Proteins 0.000 claims 2
- 108091043187 miR-30a stem-loop Proteins 0.000 claims 2
- 108091029750 miR-30a-1 stem-loop Proteins 0.000 claims 2
- 108091030035 miR-30a-2 stem-loop Proteins 0.000 claims 2
- 108091091870 miR-30a-3 stem-loop Proteins 0.000 claims 2
- 108091067477 miR-30a-4 stem-loop Proteins 0.000 claims 2
- 108091057431 miR-30d stem-loop Proteins 0.000 claims 2
- 108091030520 miR-7-2 stem-loop Proteins 0.000 claims 2
- 108091089992 miR-9-1 stem-loop Proteins 0.000 claims 2
- 229940046166 oligodeoxynucleotide Drugs 0.000 claims 2
- 108091007774 MIR107 Proteins 0.000 claims 1
- 108091046841 MiR-150 Proteins 0.000 claims 1
- 108091028141 MiR-203 Proteins 0.000 claims 1
- 108091028049 Mir-221 microRNA Proteins 0.000 claims 1
- 108091062140 Mir-223 Proteins 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 208000029742 colonic neoplasm Diseases 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 239000012634 fragment Substances 0.000 claims 1
- 108091064157 miR-106a stem-loop Proteins 0.000 claims 1
- 108091064138 miR-129-2 stem-loop Proteins 0.000 claims 1
- 108091074848 miR-19 stem-loop Proteins 0.000 claims 1
- 108091056296 miR-196-1 stem-loop Proteins 0.000 claims 1
- 108091049679 miR-20a stem-loop Proteins 0.000 claims 1
- 108091061917 miR-221 stem-loop Proteins 0.000 claims 1
- 108091063489 miR-221-1 stem-loop Proteins 0.000 claims 1
- 108091055391 miR-221-2 stem-loop Proteins 0.000 claims 1
- 108091031076 miR-221-3 stem-loop Proteins 0.000 claims 1
- 108091048857 miR-24-1 stem-loop Proteins 0.000 claims 1
- 108091047483 miR-24-2 stem-loop Proteins 0.000 claims 1
- 108091025088 miR-29b-2 stem-loop Proteins 0.000 claims 1
- 108091055059 miR-30c stem-loop Proteins 0.000 claims 1
- 108091024082 miR-32 stem-loop Proteins 0.000 claims 1
- 108091076838 miR-9-3 stem-loop Proteins 0.000 claims 1
- 239000002679 microRNA Substances 0.000 claims 1
- 238000002493 microarray Methods 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75658506P | 2006-01-05 | 2006-01-05 | |
| US60/756,585 | 2006-01-05 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012183280A Division JP5743982B2 (ja) | 2006-01-05 | 2012-08-22 | 固形癌の診断及び治療のためのマイクロrnaに基づく方法及び組成物 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015141189A Division JP2016025853A (ja) | 2006-01-05 | 2015-07-15 | 固形癌の診断及び治療のためのマイクロrnaに基づく方法及び組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014060993A JP2014060993A (ja) | 2014-04-10 |
| JP2014060993A5 true JP2014060993A5 (enExample) | 2014-12-11 |
| JP5837909B2 JP5837909B2 (ja) | 2015-12-24 |
Family
ID=38256892
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008549555A Expired - Fee Related JP5395439B2 (ja) | 2006-01-05 | 2007-01-03 | 固形癌の診断及び治療のためのマイクロrnaに基づく方法及び組成物 |
| JP2012183280A Expired - Fee Related JP5743982B2 (ja) | 2006-01-05 | 2012-08-22 | 固形癌の診断及び治療のためのマイクロrnaに基づく方法及び組成物 |
| JP2013216256A Expired - Fee Related JP5837909B2 (ja) | 2006-01-05 | 2013-10-17 | 固形癌の診断及び治療のためのマイクロrnaに基づく方法及び組成物 |
| JP2015141189A Pending JP2016025853A (ja) | 2006-01-05 | 2015-07-15 | 固形癌の診断及び治療のためのマイクロrnaに基づく方法及び組成物 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008549555A Expired - Fee Related JP5395439B2 (ja) | 2006-01-05 | 2007-01-03 | 固形癌の診断及び治療のためのマイクロrnaに基づく方法及び組成物 |
| JP2012183280A Expired - Fee Related JP5743982B2 (ja) | 2006-01-05 | 2012-08-22 | 固形癌の診断及び治療のためのマイクロrnaに基づく方法及び組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015141189A Pending JP2016025853A (ja) | 2006-01-05 | 2015-07-15 | 固形癌の診断及び治療のためのマイクロrnaに基づく方法及び組成物 |
Country Status (8)
| Country | Link |
|---|---|
| US (24) | US8148069B2 (enExample) |
| EP (31) | EP2484782B1 (enExample) |
| JP (4) | JP5395439B2 (enExample) |
| CN (3) | CN105907842A (enExample) |
| AU (1) | AU2007205163B2 (enExample) |
| CA (1) | CA2633754C (enExample) |
| ES (22) | ES2537880T3 (enExample) |
| WO (1) | WO2007081740A2 (enExample) |
Families Citing this family (311)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
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| EP2471924A1 (en) | 2004-05-28 | 2012-07-04 | Asuragen, INC. | Methods and compositions involving microRNA |
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| US20090209621A1 (en) * | 2005-06-03 | 2009-08-20 | The Johns Hopkins University | Compositions and methods for decreasing microrna expression for the treatment of neoplasia |
| WO2007016548A2 (en) * | 2005-08-01 | 2007-02-08 | The Ohio State University Research Foundation | Micro-rna-based methods and compositions for the diagnosis, prognosis and treatment of breast cancer |
| US8481505B2 (en) | 2005-09-12 | 2013-07-09 | The Ohio State University Research Foundation | Compositions and methods for the diagnosis and therapy of BCL2-associated cancers |
| US8445198B2 (en) * | 2005-12-01 | 2013-05-21 | Medical Prognosis Institute | Methods, kits and devices for identifying biomarkers of treatment response and use thereof to predict treatment efficacy |
| AU2007205234B2 (en) | 2006-01-05 | 2012-07-12 | The Ohio State University Research Foundation | MicroRNA-based methods and compositions for the diagnosis, prognosis and treatment of lung cancer |
| WO2007081680A2 (en) | 2006-01-05 | 2007-07-19 | The Ohio State University Research Foundation | Microrna expression abnormalities in pancreatic endocrine and acinar tumors |
| EP2484782B1 (en) | 2006-01-05 | 2015-11-18 | The Ohio State University Research Foundation | MicroRNA-based methods and compositions for the diagnosis and treatment of solid cancers |
| ES2446362T3 (es) | 2006-03-20 | 2014-03-07 | The Ohio State University Research Foundation | Huellas de microARN durante megacariocipoyesis humana |
| ES2425387T3 (es) * | 2006-07-13 | 2013-10-15 | The Ohio State University Research Foundation | Mir-106a para diagnosticar adenocarcinoma de colon de pronóstico de supervivencia pobre |
| US8071292B2 (en) | 2006-09-19 | 2011-12-06 | The Ohio State University Research Foundation | Leukemia diagnostic methods |
| WO2008054828A2 (en) | 2006-11-01 | 2008-05-08 | The Ohio State University Research Foundation | Microrna expression signature for predicting survival and metastases in hepatocellular carcinoma |
| US8975026B2 (en) * | 2007-01-16 | 2015-03-10 | Somalogic, Inc. | Method for generating aptamers with improved off-rates |
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| CN101827941B (zh) * | 2007-04-30 | 2014-07-16 | 俄亥俄州立大学研究基金会 | 用于区分胰腺癌与正常胰腺功能和/或慢性胰腺炎的方法 |
| US8697672B2 (en) * | 2007-05-16 | 2014-04-15 | California Institute Of Technology | Microrna inhibition for the treatment of inflammation and myeloproliferative disorders |
| CA2688536A1 (en) * | 2007-05-21 | 2008-11-27 | Dana-Farber Cancer Institute, Inc. | Compositions, kits, and methods for identification, assessment, prevention, and therapy of cancer |
| US8465917B2 (en) | 2007-06-08 | 2013-06-18 | The Ohio State University Research Foundation | Methods for determining heptocellular carcinoma subtype and detecting hepatic cancer stem cells |
| US8053186B2 (en) | 2007-06-15 | 2011-11-08 | The Ohio State University Research Foundation | Oncogenic ALL-1 fusion proteins for targeting Drosha-mediated microRNA processing |
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| DK2182969T3 (en) | 2007-07-31 | 2017-02-27 | Univ Texas | Micro-RNA family that modulates fibrosis and its applications |
| EP2173911B1 (en) | 2007-07-31 | 2014-06-18 | The Ohio State University Research Foundation | Methods for reverting methylation by targeting dnmt3a and dnmt3b |
| EP2653561B1 (en) | 2007-08-03 | 2016-03-02 | The Ohio State University Research Foundation | Ultraconserved regions encoding ncRNAs |
| WO2009021235A2 (en) * | 2007-08-09 | 2009-02-12 | The Regents Of The University Of Colorado | Methods and compositions for treating cancer |
| CA2733676A1 (en) | 2007-08-10 | 2009-02-19 | British Columbia Cancer Agency Branch | Microrna compositions and methods for the treatment of myelogenous leukemia |
| EP3028708A1 (en) | 2007-08-22 | 2016-06-08 | The Ohio State University Research Foundation | Methods and compositions for inducing deregulation of epha7 and erk phosphorylation in human acute leukemias |
| WO2009024790A1 (en) * | 2007-08-23 | 2009-02-26 | Isis Innovation Limited | Method and kit for the prognosis of cancer by determining the level of mirna-210 |
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| BRPI0816852A2 (pt) | 2007-09-14 | 2017-06-06 | Univ Ohio State Res Found | método de diagnosticar ou prognosticar doença ou desordem em sujeito, biomarcador, método para determinar e/ou prever se sujeito tem diferenciação da desordem, biomarcador para desordem pulmonar, método para diagnosticar se sujeito tem, ou está em risco de desenvolver doença ou desordem, método de inibir a proliferação de doença ou desordem e método para identificar agente terapêutico do câncer. |
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| US20090233297A1 (en) * | 2008-03-06 | 2009-09-17 | Elizabeth Mambo | Microrna markers for recurrence of colorectal cancer |
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| US9217155B2 (en) | 2008-05-28 | 2015-12-22 | University Of Massachusetts | Isolation of novel AAV'S and uses thereof |
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| US20100322909A1 (en) * | 2009-06-17 | 2010-12-23 | The University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Th1-associated micrornas and their use for tumor immunotherapy |
| WO2011017089A1 (en) * | 2009-07-27 | 2011-02-10 | The Regents Of The University Of Colorado, A Body Corporate | Mirna inhibition of six1 expression |
| CN101988061A (zh) * | 2009-07-30 | 2011-03-23 | 江苏命码生物科技有限公司 | 乳腺癌检测标记物及其检测方法、试剂盒和生物芯片 |
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| CN102770561B (zh) * | 2009-12-24 | 2015-05-06 | 复旦大学 | 用于诊断不同亚型肺癌的基于组织的微-rna方法 |
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| CN102782155B (zh) * | 2009-12-24 | 2016-05-04 | 复旦大学 | 用于肺癌的血浆中微rna表达谱分析的组合物和方法 |
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