ES2616789T3 - Inhibidores de tirosina cinasa de Bruton - Google Patents

Inhibidores de tirosina cinasa de Bruton Download PDF

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Publication number
ES2616789T3
ES2616789T3 ES12166300.9T ES12166300T ES2616789T3 ES 2616789 T3 ES2616789 T3 ES 2616789T3 ES 12166300 T ES12166300 T ES 12166300T ES 2616789 T3 ES2616789 T3 ES 2616789T3
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Spain
Prior art keywords
acid
compound
formula
compounds
cases
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Active
Application number
ES12166300.9T
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English (en)
Spanish (es)
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ES2616789T8 (es
Inventor
Lee Honigberg
Erik Verner
Zhengying Pan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacyclics LLC
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Pharmacyclics LLC
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
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    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2887—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
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    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Urology & Nephrology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Obesity (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Reproductive Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pain & Pain Management (AREA)
ES12166300.9T 2006-09-22 2006-12-28 Inhibidores de tirosina cinasa de Bruton Active ES2616789T3 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US82672006P 2006-09-22 2006-09-22
US826720P 2006-09-22
US82859006P 2006-10-06 2006-10-06
US828590P 2006-10-06

Publications (2)

Publication Number Publication Date
ES2616789T3 true ES2616789T3 (es) 2017-06-14
ES2616789T8 ES2616789T8 (es) 2020-12-09

Family

ID=39225888

Family Applications (8)

Application Number Title Priority Date Filing Date
ES12166301.7T Active ES2537399T3 (es) 2006-09-22 2006-12-28 Inhibidores de tirosina cinasa de Bruton
ES12166305.8T Active ES2564647T3 (es) 2006-09-22 2006-12-28 Inhibidores de tirosina cinasa de Bruton
ES10155834T Active ES2376424T3 (es) 2006-09-22 2006-12-28 Inhibidores de tirosina cinasa de bruton.
ES12166302.5T Active ES2673973T3 (es) 2006-09-22 2006-12-28 Inhibidores de tirosina cinasa de Bruton
ES06850039.6T Active ES2585902T3 (es) 2006-09-22 2006-12-28 Inhibidores de tirosina cinasa de Bruton
ES12166300.9T Active ES2616789T3 (es) 2006-09-22 2006-12-28 Inhibidores de tirosina cinasa de Bruton
ES12166298.5T Active ES2617150T3 (es) 2006-09-22 2006-12-28 Inhibidores de tirosina cinasa de Bruton
ES12166295.1T Active ES2584331T3 (es) 2006-09-22 2006-12-28 Inhibidores de tirosina cinasa de Bruton

Family Applications Before (5)

Application Number Title Priority Date Filing Date
ES12166301.7T Active ES2537399T3 (es) 2006-09-22 2006-12-28 Inhibidores de tirosina cinasa de Bruton
ES12166305.8T Active ES2564647T3 (es) 2006-09-22 2006-12-28 Inhibidores de tirosina cinasa de Bruton
ES10155834T Active ES2376424T3 (es) 2006-09-22 2006-12-28 Inhibidores de tirosina cinasa de bruton.
ES12166302.5T Active ES2673973T3 (es) 2006-09-22 2006-12-28 Inhibidores de tirosina cinasa de Bruton
ES06850039.6T Active ES2585902T3 (es) 2006-09-22 2006-12-28 Inhibidores de tirosina cinasa de Bruton

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