ECSP11004702A - Combinaciones deactivador(es) del receptor de activación de proliferacion peroxismal (ppar) e inhibidor(es) de absorcion de esterol y tratamientos para indicaciones vasculares - Google Patents

Combinaciones deactivador(es) del receptor de activación de proliferacion peroxismal (ppar) e inhibidor(es) de absorcion de esterol y tratamientos para indicaciones vasculares

Info

Publication number
ECSP11004702A
ECSP11004702A EC2011004702A ECSP11004702A ECSP11004702A EC SP11004702 A ECSP11004702 A EC SP11004702A EC 2011004702 A EC2011004702 A EC 2011004702A EC SP11004702 A ECSP11004702 A EC SP11004702A EC SP11004702 A ECSP11004702 A EC SP11004702A
Authority
EC
Ecuador
Prior art keywords
peroxismal
combinations
deactivator
ppar
treatments
Prior art date
Application number
EC2011004702A
Other languages
English (en)
Inventor
Harry R Davis
Teddy Kosogluo
Giles Jean Bernard Picard
Phillip Cho Wing-Kee
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26950511&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP11004702(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Corp filed Critical Schering Corp
Publication of ECSP11004702A publication Critical patent/ECSP11004702A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/02Halogenated hydrocarbons
    • A61K31/025Halogenated hydrocarbons carbocyclic
    • A61K31/03Halogenated hydrocarbons carbocyclic aromatic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05Phenols
    • A61K31/055Phenols the aromatic ring being substituted by halogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/397Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente invención suministra composiciones, combinaciones terapéuticas y métodos que incluyen: (a) por lo menos un activador del receptor de activación de proliferación peroxismal; y (b) por lo menos un inhibidor de absorción de esterol de azetidinona sustituida o de ?-lactama sustituida que puede ser útil en el tratamiento de condiciones vasculares, diabetes, obesidad y reducción de los niveles plasmáticos de esteroles.
EC2011004702A 2001-01-26 2011-02-09 Combinaciones deactivador(es) del receptor de activación de proliferacion peroxismal (ppar) e inhibidor(es) de absorcion de esterol y tratamientos para indicaciones vasculares ECSP11004702A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26439601P 2001-01-26 2001-01-26
US32383901P 2001-09-21 2001-09-21

Publications (1)

Publication Number Publication Date
ECSP11004702A true ECSP11004702A (es) 2011-03-31

Family

ID=26950511

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2011004702A ECSP11004702A (es) 2001-01-26 2011-02-09 Combinaciones deactivador(es) del receptor de activación de proliferacion peroxismal (ppar) e inhibidor(es) de absorcion de esterol y tratamientos para indicaciones vasculares

Country Status (33)

Country Link
US (5) US20020151536A1 (es)
EP (2) EP1353696B1 (es)
JP (4) JP4777602B2 (es)
KR (1) KR100596257B1 (es)
CN (1) CN100509058C (es)
AR (2) AR033855A1 (es)
AT (2) ATE374641T1 (es)
AU (1) AU2002247019C1 (es)
BR (1) BR0206654A (es)
CA (3) CA2434682C (es)
CL (1) CL2004001174A1 (es)
CY (2) CY1108000T1 (es)
CZ (2) CZ309209B6 (es)
DE (2) DE60222773T2 (es)
DK (2) DK1353696T3 (es)
EC (1) ECSP11004702A (es)
ES (2) ES2274013T3 (es)
HK (2) HK1063607A1 (es)
HU (2) HUP0303915A3 (es)
IL (3) IL156445A0 (es)
ME (1) MEP27808A (es)
MX (1) MXPA03006725A (es)
NO (1) NO331512B1 (es)
NZ (1) NZ525921A (es)
PL (1) PL208110B1 (es)
PT (2) PT1353696E (es)
RS (2) RS20100015A (es)
RU (1) RU2356550C2 (es)
SI (2) SI1413331T1 (es)
SK (2) SK287988B6 (es)
TW (1) TWI337083B (es)
WO (1) WO2002058732A2 (es)
ZA (1) ZA200305693B (es)

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