DE69115702T2 - Verbindungen und verfahren zur unterdrückung der genexpression - Google Patents

Verbindungen und verfahren zur unterdrückung der genexpression

Info

Publication number
DE69115702T2
DE69115702T2 DE69115702T DE69115702T DE69115702T2 DE 69115702 T2 DE69115702 T2 DE 69115702T2 DE 69115702 T DE69115702 T DE 69115702T DE 69115702 T DE69115702 T DE 69115702T DE 69115702 T2 DE69115702 T2 DE 69115702T2
Authority
DE
Germany
Prior art keywords
independently
hydrogen
oxygen
oligonucleoside
integer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69115702T
Other languages
German (de)
English (en)
Other versions
DE69115702D1 (de
Inventor
Paul Cavanaugh
Prasad Chaturvedula
Daniel Delecki
Frederick Hausheer
Patricia Moskwa
Fred Oakes
Alexander Weis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi SA
Original Assignee
Sterling Winthrop Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/562,180 external-priority patent/US5245022A/en
Application filed by Sterling Winthrop Inc filed Critical Sterling Winthrop Inc
Application granted granted Critical
Publication of DE69115702D1 publication Critical patent/DE69115702D1/de
Publication of DE69115702T2 publication Critical patent/DE69115702T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Golf Clubs (AREA)
  • Adhesives Or Adhesive Processes (AREA)
DE69115702T 1990-08-03 1991-08-02 Verbindungen und verfahren zur unterdrückung der genexpression Expired - Fee Related DE69115702T2 (de)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US07/562,180 US5245022A (en) 1990-08-03 1990-08-03 Exonuclease resistant terminally substituted oligonucleotides
US58245690A 1990-09-13 1990-09-13
US58228790A 1990-09-13 1990-09-13
US58245790A 1990-09-13 1990-09-13
US68278491A 1991-04-09 1991-04-09
PCT/US1991/005531 WO1992002534A2 (en) 1990-08-03 1991-08-02 Compounds and methods for inhibiting gene expression

Publications (2)

Publication Number Publication Date
DE69115702D1 DE69115702D1 (de) 1996-02-01
DE69115702T2 true DE69115702T2 (de) 1996-06-13

Family

ID=27541908

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69115702T Expired - Fee Related DE69115702T2 (de) 1990-08-03 1991-08-02 Verbindungen und verfahren zur unterdrückung der genexpression

Country Status (20)

Country Link
US (1) US5677439A (enExample)
EP (1) EP0541722B1 (enExample)
JP (1) JPH06502300A (enExample)
KR (1) KR100211552B1 (enExample)
AT (1) ATE131827T1 (enExample)
AU (2) AU667459B2 (enExample)
BR (1) BR9106729A (enExample)
CA (1) CA2088673A1 (enExample)
DE (1) DE69115702T2 (enExample)
DK (1) DK0541722T3 (enExample)
ES (1) ES2083593T3 (enExample)
FI (1) FI930455L (enExample)
GR (1) GR3018881T3 (enExample)
HU (2) HU217036B (enExample)
IL (3) IL99066A (enExample)
MY (1) MY107332A (enExample)
NZ (1) NZ239247A (enExample)
PT (1) PT98562B (enExample)
TW (1) TW222641B (enExample)
WO (1) WO1992002534A2 (enExample)

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