|
US6811779B2
(en)
|
1994-02-10 |
2004-11-02 |
Imclone Systems Incorporated |
Methods for reducing tumor growth with VEGF receptor antibody combined with radiation and chemotherapy
|
|
TW321649B
(instruction)
*
|
1994-11-12 |
1997-12-01 |
Zeneca Ltd |
|
|
GB9424233D0
(en)
*
|
1994-11-30 |
1995-01-18 |
Zeneca Ltd |
Quinazoline derivatives
|
|
GB9508565D0
(en)
*
|
1995-04-27 |
1995-06-14 |
Zeneca Ltd |
Quiazoline derivative
|
|
GB9508535D0
(en)
*
|
1995-04-27 |
1995-06-14 |
Zeneca Ltd |
Quinazoline derivative
|
|
US5932574A
(en)
*
|
1995-04-27 |
1999-08-03 |
Zeneca Limited |
Quinazoline derivatives
|
|
GB9508537D0
(en)
*
|
1995-04-27 |
1995-06-14 |
Zeneca Ltd |
Quinazoline derivatives
|
|
GB9508538D0
(en)
*
|
1995-04-27 |
1995-06-14 |
Zeneca Ltd |
Quinazoline derivatives
|
|
GB9624482D0
(en)
|
1995-12-18 |
1997-01-15 |
Zeneca Phaema S A |
Chemical compounds
|
|
BR9707495A
(pt)
|
1996-02-13 |
1999-07-27 |
Zeneca Ltd |
Derivado de quinazolina processo para a preparação do mesmo composição farmacêutica e processo para a produç o de um efeito antiangiogênico e/ou de redução de permeabilidade vascular em um animal de sangue quente
|
|
GB9603097D0
(en)
*
|
1996-02-14 |
1996-04-10 |
Zeneca Ltd |
Quinazoline compounds
|
|
GB9603095D0
(en)
*
|
1996-02-14 |
1996-04-10 |
Zeneca Ltd |
Quinazoline derivatives
|
|
KR100489174B1
(ko)
|
1996-03-05 |
2005-09-30 |
제네카-파마 소시에떼아노님 |
4-아닐리노퀴나졸린유도체
|
|
RO121900B1
(ro)
|
1996-04-12 |
2008-07-30 |
Warner-Lambert Company |
Compuşi inhibitori, ireversibili, ai tirozin kinazelor, compoziţie farmaceutică care îi conţine şi utilizarea acestora
|
|
GB9607729D0
(en)
*
|
1996-04-13 |
1996-06-19 |
Zeneca Ltd |
Quinazoline derivatives
|
|
JP2000512990A
(ja)
*
|
1996-06-24 |
2000-10-03 |
ファイザー・インク |
過増殖性疾患を処置するためのフェニルアミノ置換三環式誘導体
|
|
GB9718972D0
(en)
|
1996-09-25 |
1997-11-12 |
Zeneca Ltd |
Chemical compounds
|
|
EP0837063A1
(en)
*
|
1996-10-17 |
1998-04-22 |
Pfizer Inc. |
4-Aminoquinazoline derivatives
|
|
US6225318B1
(en)
|
1996-10-17 |
2001-05-01 |
Pfizer Inc |
4-aminoquinazolone derivatives
|
|
US6002008A
(en)
*
|
1997-04-03 |
1999-12-14 |
American Cyanamid Company |
Substituted 3-cyano quinolines
|
|
US6090096A
(en)
|
1997-04-23 |
2000-07-18 |
Heartport, Inc. |
Antegrade cardioplegia catheter and method
|
|
DE19743435A1
(de)
|
1997-10-01 |
1999-04-08 |
Merck Patent Gmbh |
Benzamidinderivate
|
|
US6706721B1
(en)
|
1998-04-29 |
2004-03-16 |
Osi Pharmaceuticals, Inc. |
N-(3-ethynylphenylamino)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine mesylate anhydrate and monohydrate
|
|
WO1999055683A1
(en)
*
|
1998-04-29 |
1999-11-04 |
Pfizer Products Inc. |
N-(3-ethynylphenylamino)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine mesylate anhydrate and monohydrate
|
|
US6384223B1
(en)
|
1998-07-30 |
2002-05-07 |
American Home Products Corporation |
Substituted quinazoline derivatives
|
|
WO2000010588A2
(en)
|
1998-08-18 |
2000-03-02 |
The Regents Of The University Of California |
Epidermal growth factor receptor antagonists for treating hypersecretion of mucus in the lungs
|
|
UA71945C2
(en)
|
1999-01-27 |
2005-01-17 |
Pfizer Prod Inc |
Substituted bicyclic derivatives being used as anticancer agents
|
|
JP3270834B2
(ja)
|
1999-01-27 |
2002-04-02 |
ファイザー・プロダクツ・インク |
抗がん剤として有用なヘテロ芳香族二環式誘導体
|
|
RS49836B
(sr)
*
|
1999-03-31 |
2008-08-07 |
Pfizer Products Inc., |
Postupci i intermedijeri za dobijanje anti-kancernih jedinjenja
|
|
CN1166645C
(zh)
|
1999-06-21 |
2004-09-15 |
贝林格尔英格海姆法玛两合公司 |
双环杂环化合物,含有该化合物的药物组合物,该化合物的用途及其制备方法
|
|
ES2295035T3
(es)
|
1999-07-09 |
2008-04-16 |
Glaxo Group Limited |
Anilinoquinazolinas como inhibidores de proteina tirosina quinasa.
|
|
US6933299B1
(en)
|
1999-07-09 |
2005-08-23 |
Smithkline Beecham Corporation |
Anilinoquinazolines as protein tyrosine kinase inhibitors
|
|
GB9922173D0
(en)
|
1999-09-21 |
1999-11-17 |
Zeneca Ltd |
Chemical compounds
|
|
CA2384282A1
(en)
*
|
1999-09-21 |
2001-03-29 |
Astrazeneca Ab |
Quinazoline compounds and pharmaceutical compositions containing them
|
|
GB9925958D0
(en)
|
1999-11-02 |
1999-12-29 |
Bundred Nigel J |
Therapeutic use
|
|
PT1676845E
(pt)
|
1999-11-05 |
2008-08-05 |
Astrazeneca Ab |
Novos derivados de quinazolina
|
|
UA74803C2
(uk)
*
|
1999-11-11 |
2006-02-15 |
Осі Фармасьютікалз, Інк. |
Стійкий поліморф гідрохлориду n-(3-етинілфеніл)-6,7-біс(2-метоксіетокси)-4-хіназолінаміну, спосіб його одержання (варіанти) та фармацевтичне застосування
|
|
US7087613B2
(en)
|
1999-11-11 |
2006-08-08 |
Osi Pharmaceuticals, Inc. |
Treating abnormal cell growth with a stable polymorph of N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine hydrochloride
|
|
ES2267748T3
(es)
|
2000-04-07 |
2007-03-16 |
Astrazeneca Ab |
Compuestos de quinazolina.
|
|
UA73993C2
(uk)
|
2000-06-06 |
2005-10-17 |
Астразенека Аб |
Хіназолінові похідні для лікування пухлин та фармацевтична композиція
|
|
EP1170011A1
(en)
*
|
2000-07-06 |
2002-01-09 |
Boehringer Ingelheim International GmbH |
Novel use of inhibitors of the epidermal growth factor receptor
|
|
EP1313727A1
(en)
|
2000-08-21 |
2003-05-28 |
AstraZeneca AB |
Quinazoline derivatives
|
|
CN101029022B
(zh)
|
2000-10-20 |
2011-01-12 |
卫材R&D管理有限公司 |
含氮芳环衍生物的制备方法
|
|
US7776315B2
(en)
|
2000-10-31 |
2010-08-17 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Pharmaceutical compositions based on anticholinergics and additional active ingredients
|
|
EP1330444B1
(en)
|
2000-11-01 |
2011-03-23 |
Millennium Pharmaceuticals, Inc. |
Nitrogenous heterocyclic compounds and process for making them
|
|
US7019012B2
(en)
|
2000-12-20 |
2006-03-28 |
Boehringer Ingelheim International Pharma Gmbh & Co. Kg |
Quinazoline derivatives and pharmaceutical compositions containing them
|
|
SI3351246T1
(sl)
|
2001-02-19 |
2019-08-30 |
Novartis Pharma Ag |
Derivat rapamicina za zdravljenje trdnega tumorja, povezanega z deregulirano angiogenezo
|
|
JP2002293773A
(ja)
*
|
2001-03-30 |
2002-10-09 |
Sumika Fine Chemicals Co Ltd |
キナゾリン誘導体の製造方法
|
|
RU2332415C2
(ru)
*
|
2001-04-27 |
2008-08-27 |
Вертекс Фармасьютикалз Инкорпорейтед |
Производные пиразола, полезные в качестве ингибиторов протеинкиназы
|
|
AU2002345792A1
(en)
|
2001-06-21 |
2003-01-08 |
Pfizer Inc. |
Thienopyridine and thienopyrimidine anticancer agents
|
|
WO2003000188A2
(en)
|
2001-06-21 |
2003-01-03 |
Ariad Pharmaceuticals, Inc. |
Novel quinazolines and uses thereof
|
|
US20040132101A1
(en)
|
2002-09-27 |
2004-07-08 |
Xencor |
Optimized Fc variants and methods for their generation
|
|
WO2003074529A2
(en)
|
2002-03-01 |
2003-09-12 |
Pfizer Inc. |
iNDOLYL-UREA DERIVATIVES OF THIENOPYRIDINES USEFUL AS ANTI-ANGIOGENIC AGENTS
|
|
US7078409B2
(en)
|
2002-03-28 |
2006-07-18 |
Beta Pharma, Inc. |
Fused quinazoline derivatives useful as tyrosine kinase inhibitors
|
|
US6924285B2
(en)
|
2002-03-30 |
2005-08-02 |
Boehringer Ingelheim Pharma Gmbh & Co. |
Bicyclic heterocyclic compounds, pharmaceutical compositions containing these compounds, their use and process for preparing them
|
|
DE10221018A1
(de)
|
2002-05-11 |
2003-11-27 |
Boehringer Ingelheim Pharma |
Verwendung von Hemmern der EGFR-vermittelten Signaltransduktion zur Behandlung von gutartiger Prostatahyperplasie (BPH)/Prostatahypertrophie
|
|
KR20120125398A
(ko)
|
2002-05-16 |
2012-11-14 |
노파르티스 아게 |
암에서 ｅｄｇ 수용체 결합제의 용도
|
|
UA77303C2
(en)
|
2002-06-14 |
2006-11-15 |
Pfizer |
Derivatives of thienopyridines substituted by benzocondensed heteroarylamide useful as therapeutic agents, pharmaceutical compositions and methods for their use
|
|
MXPA05000403A
(es)
|
2002-07-15 |
2005-07-22 |
Genentech Inc |
Metodos para identificar tumores que responden al tratamiento con anticuerpos contra erbb2.
|
|
AU2003279719B8
(en)
|
2002-09-27 |
2009-01-08 |
Xencor Inc. |
Optimized Fc variants and methods for their generation
|
|
US7488823B2
(en)
|
2003-11-10 |
2009-02-10 |
Array Biopharma, Inc. |
Cyanoguanidines and cyanoamidines as ErbB2 and EGFR inhibitors
|
|
NZ540092A
(en)
*
|
2002-11-20 |
2007-06-29 |
Array Biopharma Inc |
Cyanoguanidines and cyanoamidines as ErbB2 and EGFR inhibitors
|
|
US20060167026A1
(en)
*
|
2003-01-06 |
2006-07-27 |
Hiroyuki Nawa |
Antipsychotic molecular-targeting epithelial growth factor receptor
|
|
GB0302882D0
(en)
*
|
2003-02-07 |
2003-03-12 |
Univ Cardiff |
Improvements in or relating to agents for the treatment of cardiovascular dysfunction and weight loss
|
|
US7148231B2
(en)
*
|
2003-02-17 |
2006-12-12 |
Hoffmann-La Roche Inc. |
[6,7-Bis(2-methoxy-ethoxy)-quinazolin-4-yl]-(3-ethynyl-phenyl)amine hydrochloride polymorph
|
|
US7223749B2
(en)
|
2003-02-20 |
2007-05-29 |
Boehringer Ingelheim International Gmbh |
Bicyclic heterocycles, pharmaceutical compositions containing these compounds, their use and processes for preparing them
|
|
US20090010920A1
(en)
|
2003-03-03 |
2009-01-08 |
Xencor, Inc. |
Fc Variants Having Decreased Affinity for FcyRIIb
|
|
PA8595001A1
(es)
|
2003-03-04 |
2004-09-28 |
Pfizer Prod Inc |
Nuevos compuestos heteroaromaticos condensados que son inhibidores del factor de crecimiento transforante (tgf)
|
|
ATE508747T1
(de)
|
2003-03-10 |
2011-05-15 |
Eisai R&D Man Co Ltd |
C-kit kinase-hemmer
|
|
KR100812586B1
(ko)
*
|
2003-04-16 |
2008-03-13 |
에프. 호프만-라 로슈 아게 |
P38 키나아제 저해제로서 유용한 퀴나졸린 화합물
|
|
GB0309850D0
(en)
|
2003-04-30 |
2003-06-04 |
Astrazeneca Ab |
Quinazoline derivatives
|
|
MY150088A
(en)
|
2003-05-19 |
2013-11-29 |
Irm Llc |
Immunosuppressant compounds and compositions
|
|
JP4944613B2
(ja)
|
2003-05-19 |
2012-06-06 |
アイアールエム・リミテッド・ライアビリティ・カンパニー |
免疫抑制化合物および組成物
|
|
NZ543234A
(en)
|
2003-05-30 |
2009-04-30 |
Astrazeneca Uk Ltd |
Marker genes and uses thereof to identify cancer patients that will respond to erbb tyrosine kinase inhibitors
|
|
CA2528961A1
(en)
|
2003-06-09 |
2005-01-06 |
Samuel Waksal |
Methods of inhibiting receptor tyrosine kinases with an extracellular antagonist and an intracellular antagonist
|
|
AU2004247418B2
(en)
|
2003-06-10 |
2009-11-05 |
F. Hoffmann-La Roche Ag |
1.3.4-triaza-phenalene and 1,3,4,6-tetraazaphenalene derivatives
|
|
US8309562B2
(en)
|
2003-07-03 |
2012-11-13 |
Myrexis, Inc. |
Compounds and therapeutical use thereof
|
|
JP5129957B2
(ja)
|
2003-07-03 |
2013-01-30 |
ミリアド ジェネティクス， インコーポレイテッド |
カスパーゼの活性化因子およびアポトーシスの誘発因子としての４−アリールアミノ−キナゾリン
|
|
GB0317665D0
(en)
|
2003-07-29 |
2003-09-03 |
Astrazeneca Ab |
Qinazoline derivatives
|
|
US7452895B2
(en)
*
|
2003-08-14 |
2008-11-18 |
Array Biopharma Inc. |
Quinazoline analogs as receptor tyrosine kinase inhibitors
|
|
CN1838959A
(zh)
*
|
2003-08-18 |
2006-09-27 |
辉瑞产品公司 |
Erbb2抗癌剂的给药方案
|
|
CA2536321A1
(en)
|
2003-08-29 |
2005-03-10 |
Pfizer Inc. |
Thienopyridine-phenylacet amides and their derivatives useful as new anti-angiogenic agents
|
|
RU2378268C2
(ru)
|
2003-09-16 |
2010-01-10 |
Астразенека Аб |
Производные хиназолина в качестве ингибиторов тирозинкиназы
|
|
GB0322409D0
(en)
|
2003-09-25 |
2003-10-29 |
Astrazeneca Ab |
Quinazoline derivatives
|
|
US9714282B2
(en)
|
2003-09-26 |
2017-07-25 |
Xencor, Inc. |
Optimized Fc variants and methods for their generation
|
|
DE10349113A1
(de)
|
2003-10-17 |
2005-05-12 |
Boehringer Ingelheim Pharma |
Verfahren zur Herstellung von Aminocrotonylverbindungen
|
|
EP2486933B1
(en)
|
2003-11-06 |
2015-10-28 |
Seattle Genetics, Inc. |
Monomethylvaline compounds conjugated with antibodies
|
|
WO2005044788A1
(ja)
|
2003-11-11 |
2005-05-19 |
Eisai Co., Ltd. |
ウレア誘導体およびその製造方法
|
|
GB0326459D0
(en)
|
2003-11-13 |
2003-12-17 |
Astrazeneca Ab |
Quinazoline derivatives
|
|
WO2005063739A1
(en)
|
2003-12-23 |
2005-07-14 |
Pfizer Inc. |
Novel quinoline derivatives
|
|
EP1713781B1
(en)
|
2004-02-03 |
2008-11-05 |
AstraZeneca AB |
Quinazoline derivatives
|
|
JP4934432B2
(ja)
|
2004-02-19 |
2012-05-16 |
レクサン ファーマシューティカルズ インコーポレイテッド |
キナゾリン誘導体およびキナゾリン誘導体の治療への使用
|
|
MXPA06010715A
(es)
|
2004-03-19 |
2007-05-23 |
Imclone Systems Inc |
Anticuerpo del receptor del factor de crecimiento humano anti-epidermico.
|
|
CA2556227C
(en)
|
2004-03-31 |
2013-03-19 |
The General Hospital Corporation |
Method to determine responsiveness of cancer to epidermal growth factor receptor targeting treatments
|
|
RS52545B
(en)
|
2004-04-07 |
2013-04-30 |
Novartis Ag |
INHIBITORI PROTEIN APOPTOZE (IAP)
|
|
WO2005107747A2
(en)
|
2004-05-06 |
2005-11-17 |
Bioresponse, Llc |
Diindolymethane formulations for the treatment of leiomyomas
|
|
EP2286844A3
(en)
|
2004-06-01 |
2012-08-22 |
Genentech, Inc. |
Antibody-drug conjugates and methods
|
|
WO2006002422A2
(en)
|
2004-06-24 |
2006-01-05 |
Novartis Vaccines And Diagnostics Inc. |
Compounds for immunopotentiation
|
|
KR100863776B1
(ko)
|
2004-07-15 |
2008-10-16 |
젠코어 인코포레이티드 |
최적화된 Ｆｃ 변이체
|
|
US20060035893A1
(en)
|
2004-08-07 |
2006-02-16 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical compositions for treatment of respiratory and gastrointestinal disorders
|
|
DE602005013990D1
(de)
|
2004-09-17 |
2009-05-28 |
Eisai R&D Man Co Ltd |
Medizinische zusammensetzung mit verbesserter stabilität und reduzierten gelierungseigenschaften
|
|
CN104447992A
(zh)
|
2004-09-23 |
2015-03-25 |
健泰科生物技术公司 |
半胱氨酸改造的抗体和偶联物
|
|
JO3000B1
(ar)
|
2004-10-20 |
2016-09-05 |
Genentech Inc |
مركبات أجسام مضادة .
|
|
US8367805B2
(en)
|
2004-11-12 |
2013-02-05 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
|
KR101027427B1
(ko)
|
2004-11-12 |
2011-04-11 |
젠코어 인코포레이티드 |
ＦcRn에 대하여 증가된 결합력을 갖는 Ｆc 변이체
|
|
US7947676B2
(en)
|
2004-12-14 |
2011-05-24 |
Astrazeneca Ab |
Pyrazolo[3,4-d]pyrimidine compounds as antitumor agents
|
|
PE20060777A1
(es)
|
2004-12-24 |
2006-10-06 |
Boehringer Ingelheim Int |
Derivados de indolinona para el tratamiento o la prevencion de enfermedades fibroticas
|
|
DE602005026328D1
(de)
|
2004-12-30 |
2011-03-24 |
Bioresponse Llc |
Verwendung von diindolylmethan-verwandten indolen zur behandlung und prävention von erkrankungen im zusammenhang mit dem respiratory syncytial virus
|
|
EP1833482A4
(en)
|
2005-01-03 |
2011-02-16 |
Myriad Genetics Inc |
COMPOUNDS AND ITS THERAPEUTIC USE
|
|
US8258145B2
(en)
|
2005-01-03 |
2012-09-04 |
Myrexis, Inc. |
Method of treating brain cancer
|
|
US7625911B2
(en)
|
2005-01-12 |
2009-12-01 |
Mai De Ltd. |
Amorphous form of erlotinib hydrochloride and its solid amorphous dispersion
|
|
AR050418A1
(es)
|
2005-01-21 |
2006-10-25 |
Genentech Inc |
Dosificacion fija de anticuerpos her
|
|
WO2006077424A1
(en)
|
2005-01-21 |
2006-07-27 |
Astex Therapeutics Limited |
Pharmaceutical compounds
|
|
GB0501999D0
(en)
*
|
2005-02-01 |
2005-03-09 |
Sentinel Oncology Ltd |
Pharmaceutical compounds
|
|
PL1854789T3
(pl)
*
|
2005-02-23 |
2014-03-31 |
Shionogi & Co |
Pochodna chinazoliny mająca aktywność hamowania kinazy tyrozynowej
|
|
EP2399605A1
(en)
|
2005-02-23 |
2011-12-28 |
Genentech, Inc. |
Extending time to disease progression or survival in cancer patients
|
|
US8735410B2
(en)
|
2005-02-26 |
2014-05-27 |
Astrazeneca Ab |
Quinazoline derivatives as tyrosine kinase inhibitors
|
|
WO2006090930A1
(ja)
|
2005-02-28 |
2006-08-31 |
Eisai R & D Management Co., Ltd. |
スルホンアミド化合物の新規併用
|
|
CA2604735A1
(en)
*
|
2005-04-12 |
2006-10-19 |
Elan Pharma International Limited |
Nanoparticulate quinazoline derivative formulations
|
|
CN1854130B
(zh)
*
|
2005-04-15 |
2011-04-20 |
中国医学科学院药物研究所 |
喹唑啉衍生物、及其制法和药物组合物与用途
|
|
GB0510390D0
(en)
|
2005-05-20 |
2005-06-29 |
Novartis Ag |
Organic compounds
|
|
DK2100618T3
(en)
|
2005-06-17 |
2014-03-03 |
Imclone Llc |
Anti-PDGFR alpha antibody for use in the treatment of metastatic bone cancer
|
|
AU2006268227A1
(en)
|
2005-07-08 |
2007-01-18 |
Xencor, Inc |
Optimized anti-Ep-CAM antibodies
|
|
JP4989476B2
(ja)
|
2005-08-02 |
2012-08-01 |
エーザイ・アール・アンド・ディー・マネジメント株式会社 |
血管新生阻害物質の効果を検定する方法
|
|
CA2620195A1
(en)
|
2005-08-24 |
2007-03-01 |
Bristol-Myers Squibb Company |
Biomarkers and methods for determining sensitivity to epidermal growth factor receptor modulators
|
|
WO2007034144A1
(en)
|
2005-09-20 |
2007-03-29 |
Astrazeneca Ab |
4- (ih-indazol-s-yl-amino)-quinazoline compounds as erbb receptor tyrosine kinase inhibitors for the treatment of cancer
|
|
EP1931709B1
(en)
|
2005-10-03 |
2016-12-07 |
Xencor, Inc. |
Fc variants with optimized fc receptor binding properties
|
|
WO2007052850A1
(ja)
|
2005-11-07 |
2007-05-10 |
Eisai R & D Management Co., Ltd. |
血管新生阻害物質とc-kitキナーゼ阻害物質との併用
|
|
US8404697B2
(en)
|
2005-11-11 |
2013-03-26 |
Boehringer Ingelheim International Gmbh |
Quinazoline derivatives for the treatment of cancer diseases
|
|
NO20220050A1
(no)
|
2005-11-21 |
2008-08-12 |
Novartis Ag |
Neuroendokrin tumorbehandling
|
|
US7960545B2
(en)
|
2005-11-23 |
2011-06-14 |
Natco Pharma Limited |
Process for the prepartion of erlotinib
|
|
ATE488237T1
(de)
*
|
2005-12-05 |
2010-12-15 |
Pfizer Prod Inc |
Verfahren zur behandlung von abnormalem zellwachstum
|
|
CN101003514A
(zh)
|
2006-01-20 |
2007-07-25 |
上海艾力斯医药科技有限公司 |
喹唑啉衍生物、其制备方法及用途
|
|
JO2660B1
(en)
|
2006-01-20 |
2012-06-17 |
نوفارتيس ايه جي |
Pi-3 inhibitors and methods of use
|
|
MX2008009977A
(es)
|
2006-02-03 |
2009-02-27 |
Imclone Llc |
Antagonistas de receptor de factor de crecimiento de tipo insulina (igf-ir) como auxiliares para el tratamiento de cancer de prostata.
|
|
GB0605120D0
(en)
|
2006-03-14 |
2006-04-26 |
Novartis Ag |
Organic Compounds
|
|
US20090098137A1
(en)
|
2006-04-05 |
2009-04-16 |
Novartis Ag |
Combinations of therapeutic agents for treating cancer
|
|
CN101415424B
(zh)
|
2006-04-05 |
2012-12-05 |
诺瓦提斯公司 |
用于治疗癌症、包含bcr-abl/c-kit/pdgf-r tk抑制剂的组合
|
|
AR060358A1
(es)
|
2006-04-06 |
2008-06-11 |
Novartis Vaccines & Diagnostic |
Quinazolinas para la inhibicion de pdk 1
|
|
JP2009534400A
(ja)
|
2006-04-19 |
2009-09-24 |
ノバルティス アクチエンゲゼルシャフト |
インダゾール化合物およびｃｄｃ７の阻害方法
|
|
RU2469721C2
(ru)
|
2006-05-09 |
2012-12-20 |
Новартис Аг |
Комбинация, включающая комплексон железа и противоопухолевый агент, и ее применение
|
|
CN104706637A
(zh)
|
2006-05-18 |
2015-06-17 |
卫材R&D管理有限公司 |
针对甲状腺癌的抗肿瘤剂
|
|
WO2007138612A2
(en)
*
|
2006-05-25 |
2007-12-06 |
Vittal Mallya Scientific Research Foundation |
A process for synthesis of [6,7-bis-(2-methoxyethoxy)-quinazolin-4- yl]-(3-ethynylphenyl)amine hydrochloride
|
|
WO2007138613A2
(en)
*
|
2006-05-25 |
2007-12-06 |
Vittal Mallya Scientific Research Foundation |
A process for synthesis of [6,7-bis-(2-methoxyethoxy)-quinazolin-4-yl]-(3-ethynylphenyl)amine hydrochloride
|
|
CA2659307A1
(en)
*
|
2006-07-28 |
2008-01-31 |
Synthon B.V. |
Crystalline erlotinib
|
|
RS53263B
(en)
|
2006-08-14 |
2014-08-29 |
Xencor Inc. |
CD19 OPTIMIZED ANTIBODY
|
|
KR101472600B1
(ko)
|
2006-08-28 |
2014-12-15 |
에자이 알앤드디 매니지먼트 가부시키가이샤 |
미분화형 위암에 대한 항종양제
|
|
US20100008910A1
(en)
|
2006-09-12 |
2010-01-14 |
John Chant |
Methods and compositions for the diagnosis and treatment of cancer
|
|
KR20090074202A
(ko)
|
2006-09-18 |
2009-07-06 |
베링거 인겔하임 인터내셔날 게엠베하 |
Ｅｇｆｒ 돌연변이를 갖는 암을 치료하는 방법
|
|
AU2007302263A1
(en)
|
2006-09-29 |
2008-04-03 |
Novartis Ag |
Pyrazolopyrimidines as P13K lipid kinase inhibitors
|
|
CN101547922B
(zh)
|
2006-10-04 |
2012-06-20 |
辉瑞产品公司 |
作为钙受体拮抗剂的吡啶并[4,3-d]嘧啶-4(3H)-酮衍生物
|
|
US8916552B2
(en)
|
2006-10-12 |
2014-12-23 |
Astex Therapeutics Limited |
Pharmaceutical combinations
|
|
JP5528807B2
(ja)
|
2006-10-12 |
2014-06-25 |
アステックス、セラピューティックス、リミテッド |
複合薬剤
|
|
US8372856B2
(en)
|
2006-10-27 |
2013-02-12 |
Synthon Bv |
Hydrates of erlotinib hydrochloride
|
|
WO2008057253A2
(en)
|
2006-10-27 |
2008-05-15 |
Bioresponse, L.L.C. |
Anti-parasitic methods and compositions utilizing diindolylmethane-related indoles
|
|
EP1921070A1
(de)
|
2006-11-10 |
2008-05-14 |
Boehringer Ingelheim Pharma GmbH & Co. KG |
Bicyclische Heterocyclen, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstelllung
|
|
US8343950B2
(en)
*
|
2006-12-15 |
2013-01-01 |
Concert Pharmaceuticals, Inc. |
Quinazoline derivatives and methods of treatment
|
|
EP2116246A1
(en)
|
2007-01-19 |
2009-11-11 |
Eisai R&D Management Co., Ltd. |
Composition for treatment of pancreatic cancer
|
|
EP2119707B1
(en)
|
2007-01-29 |
2015-01-14 |
Eisai R&D Management Co., Ltd. |
Composition for treatment of undifferentiated-type of gastric cancer
|
|
US7998949B2
(en)
|
2007-02-06 |
2011-08-16 |
Boehringer Ingelheim International Gmbh |
Bicyclic heterocycles, drugs containing said compounds, use thereof, and method for production thereof
|
|
CN101245050A
(zh)
|
2007-02-14 |
2008-08-20 |
上海艾力斯医药科技有限公司 |
4-苯胺喹唑啉衍生物的盐
|
|
EP2491923A3
(en)
|
2007-02-15 |
2012-12-26 |
Novartis AG |
Combinations of therapeutic agents for treating cancer
|
|
US8349855B2
(en)
|
2007-02-21 |
2013-01-08 |
Natco Pharma Limited |
Polymorphs of erlotinib hydrochloride and method of preparation
|
|
CN103432580A
(zh)
|
2007-03-02 |
2013-12-11 |
健泰科生物技术公司 |
基于低her3表达预测对her二聚化抑制剂的响应
|
|
KR101441930B1
(ko)
*
|
2007-04-04 |
2014-09-19 |
시플라 리미티드 |
에르로티닙 및 그의 약학적으로 허용가능한 염의 제조방법
|
|
DK2176298T3
(en)
|
2007-05-30 |
2018-02-12 |
Xencor Inc |
Methods and compositions for inhibiting CD32B-expressing cells
|
|
WO2008154249A2
(en)
|
2007-06-08 |
2008-12-18 |
Genentech, Inc. |
Gene expression markers of tumor resistance to her2 inhibitor treatment
|
|
BRPI0814423B1
(pt)
|
2007-07-17 |
2022-04-19 |
Plexxikon, Inc |
Compostos que modulam quinase e composição farmacêutica compreendendo os mesmos
|
|
WO2009030224A2
(de)
*
|
2007-09-07 |
2009-03-12 |
Schebo Biotech Ag |
Neue chinazolin- verbindungen und ihre verwendung zur therapie von krebserkrankungen
|
|
EP2220054A2
(en)
|
2007-10-29 |
2010-08-25 |
Natco Pharma Limited |
Novel 4-(tetrazol-5-yl)-quinazoline derivatives as anti cancer agents
|
|
AU2008345242B2
(en)
|
2007-10-31 |
2014-02-27 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
|
AU2008325608B2
(en)
|
2007-11-09 |
2013-03-14 |
Eisai R & D Management Co., Ltd. |
Combination of anti-angiogenic substance and anti-tumor platinum complex
|
|
UY31478A1
(es)
|
2007-11-21 |
2009-07-17 |
|
Inhibicion del receptor para la proteina estimulante del macrofago (ron) y métodos para el tratamiento de lo mismo
|
|
UY31545A1
(es)
|
2007-12-20 |
2009-08-03 |
|
Nuevos derivados de 2-carboxamida cianoaminourea, sus sales y profarmacos farmacéuticamente aceptables, procesos de preparacion y aplicaciones
|
|
US8143250B2
(en)
|
2008-01-18 |
2012-03-27 |
Natco Pharma Limited |
6-7,dialkoxy quinazoline derivatives useful for treatment of cancer related disorders
|
|
TWI472339B
(zh)
|
2008-01-30 |
2015-02-11 |
Genentech Inc |
包含結合至ｈｅｒ２結構域ii之抗體及其酸性變異體的組合物
|
|
JP5336516B2
(ja)
|
2008-02-07 |
2013-11-06 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
スピロ環式複素環化合物、該化合物を含む医薬品、その使用及びその製造方法
|
|
JP5490092B2
(ja)
|
2008-03-24 |
2014-05-14 |
ノバルティス アーゲー |
アリールスルホンアミドをベースとするマトリクスメタロプロテアーゼ阻害剤
|
|
CN101544609A
(zh)
|
2008-03-25 |
2009-09-30 |
上海艾力斯医药科技有限公司 |
4-苯胺喹唑啉衍生物的结晶形式
|
|
MY150437A
(en)
|
2008-03-26 |
2014-01-30 |
Novartis Ag |
Hydroxamate-based inhibitors of deacetylases b
|
|
KR20110005828A
(ko)
*
|
2008-03-28 |
2011-01-19 |
콘서트 파마슈티컬즈, 인크. |
퀴나졸린 유도체 및 치료방법
|
|
AU2009247782C1
(en)
|
2008-05-13 |
2013-09-19 |
Astrazeneca Ab |
Fumarate salt of 4- (3-chloro-2-fluoroanilino) -7-methoxy-6- { [1- (N-methylcarbamoylmethyl) piperidin- 4-yl] oxy } quinazoline
|
|
WO2009140409A1
(en)
|
2008-05-14 |
2009-11-19 |
Genomic Health Inc. |
Predictors of patient response to treatment with egf receptor inhibitors
|
|
CN101584696A
(zh)
|
2008-05-21 |
2009-11-25 |
上海艾力斯医药科技有限公司 |
包含喹唑啉衍生物的组合物及制备方法、用途
|
|
DE102008031039A1
(de)
|
2008-06-30 |
2009-12-31 |
Dömling, Alexander, Priv.-Doz. Dr. |
Tarceva zur Anwendung in der Organtransplantation.
|
|
JP5539351B2
(ja)
|
2008-08-08 |
2014-07-02 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
シクロヘキシルオキシ置換ヘテロ環、これらの化合物を含有する医薬、およびそれらを生成するための方法
|
|
ES2704986T3
(es)
|
2008-10-16 |
2019-03-21 |
Celator Pharmaceuticals Inc |
Combinaciones de una camptotecina liposomal soluble en agua con cetuximab o bevacizumab
|
|
CA2742986C
(en)
|
2008-11-07 |
2015-03-31 |
Triact Therapeutics, Inc. |
Use of catecholic butane derivatives in cancer therapy
|
|
CN102209538B
(zh)
|
2008-11-11 |
2013-06-12 |
伊莱利利公司 |
P70 s6激酶抑制剂和egfr抑制剂的组合治疗剂
|
|
EP2379498B1
(en)
|
2008-12-18 |
2015-01-21 |
Novartis AG |
Polymorphic form of 1-(4-{1-[(e)-4-cyclohexyl-3-trifluoromethyl-benzyloxyimino]-ethyl}-2-ethyl-benzyl) -azetidine-3-carboxylic acid
|
|
AU2009335887A1
(en)
|
2008-12-18 |
2011-06-30 |
Novartis Ag |
New salts
|
|
IL294514A
(en)
|
2008-12-18 |
2022-09-01 |
Novartis Ag |
Hemifumarate salt of 1- [4- [1- ( 4 -cyclohexyl-3 -trifluoromethyl-benzyloxyimino ) -ethyl] -2 -ethyl-benzyl] -a zetidine-3-carboxylic acid
|
|
WO2010083617A1
(en)
|
2009-01-21 |
2010-07-29 |
Oncalis Ag |
Pyrazolopyrimidines as protein kinase inhibitors
|
|
TW201031406A
(en)
|
2009-01-29 |
2010-09-01 |
Novartis Ag |
Substituted benzimidazoles for the treatment of astrocytomas
|
|
EP2213281A1
(en)
|
2009-02-02 |
2010-08-04 |
Ratiopharm GmbH |
Pharmaceutical composition comprising N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine hydrochloride
|
|
WO2010099139A2
(en)
|
2009-02-25 |
2010-09-02 |
Osi Pharmaceuticals, Inc. |
Combination anti-cancer therapy
|
|
JP2012519170A
(ja)
|
2009-02-26 |
2012-08-23 |
オーエスアイ・ファーマシューティカルズ，エルエルシー |
生体内の腫瘍細胞のｅｍｔステータスをモニターするためのｉｎｓｉｔｕ法
|
|
WO2010099138A2
(en)
|
2009-02-27 |
2010-09-02 |
Osi Pharmaceuticals, Inc. |
Methods for the identification of agents that inhibit mesenchymal-like tumor cells or their formation
|
|
EP2401614A1
(en)
|
2009-02-27 |
2012-01-04 |
OSI Pharmaceuticals, LLC |
Methods for the identification of agents that inhibit mesenchymal-like tumor cells or their formation
|
|
JP2012519282A
(ja)
|
2009-02-27 |
2012-08-23 |
オーエスアイ・ファーマシューティカルズ，エルエルシー |
間葉様腫瘍細胞またはその生成を阻害する薬剤を同定するための方法
|
|
US20120064072A1
(en)
|
2009-03-18 |
2012-03-15 |
Maryland Franklin |
Combination Cancer Therapy Comprising Administration of an EGFR Inhibitor and an IGF-1R Inhibitor
|
|
CN102438995B
(zh)
|
2009-03-26 |
2014-12-17 |
兰贝克赛实验室有限公司 |
厄洛替尼或其药学上可接受的盐的制备工艺
|
|
GEP20156250B
(en)
|
2009-06-26 |
2015-02-25 |
Novartis Ag |
1,3-disubstituted imidazolidin-2-one derivatives as inhibitors of cyp 17
|
|
US8293753B2
(en)
|
2009-07-02 |
2012-10-23 |
Novartis Ag |
Substituted 2-carboxamide cycloamino ureas
|
|
HUE044629T2
(hu)
|
2009-07-06 |
2019-11-28 |
Boehringer Ingelheim Int |
Eljárás BIBW2992, annak sói, valamint e hatóanyagot tartalmazó szilárd gyógyászati készítmények szárítására
|
|
US9050341B2
(en)
*
|
2009-07-14 |
2015-06-09 |
Natco Pharma Limited |
Methods of treating drug resistant and other tumors by administering 6,7-dialkoxy quinazoline derivatives
|
|
US9345661B2
(en)
|
2009-07-31 |
2016-05-24 |
Genentech, Inc. |
Subcutaneous anti-HER2 antibody formulations and uses thereof
|
|
US8389526B2
(en)
|
2009-08-07 |
2013-03-05 |
Novartis Ag |
3-heteroarylmethyl-imidazo[1,2-b]pyridazin-6-yl derivatives
|
|
BR112012003262A8
(pt)
|
2009-08-12 |
2016-05-17 |
Novartis Ag |
compostos de hidrazona heterocíclica e seus usos para tratar câncer e inflamação
|
|
PE20121148A1
(es)
|
2009-08-17 |
2012-09-07 |
Intellikine Llc |
Compuestos heterociclicos y usos de los mismos
|
|
EA201200318A1
(ru)
|
2009-08-20 |
2012-09-28 |
Новартис Аг |
Гетероциклические оксимы
|
|
EA201200321A1
(ru)
|
2009-08-26 |
2012-09-28 |
Новартис Аг |
Тетразамещенные гетероарильные соединения и их применение в качестве модуляторов mdm2 и/или mdm4
|
|
US9493578B2
(en)
|
2009-09-02 |
2016-11-15 |
Xencor, Inc. |
Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens
|
|
US20120220594A1
(en)
|
2009-10-30 |
2012-08-30 |
Bristol-Meyers Squibb Company |
Methods for treating cancer in patients having igf-1r inhibitor resistance
|
|
CA2779935A1
(en)
|
2009-11-04 |
2011-05-12 |
Novartis Ag |
Heterocyclic sulfonamide derivatives useful as mek inhibitors
|
|
EP2510110A1
(en)
|
2009-11-13 |
2012-10-17 |
Pangaea Biotech S.L. |
Molecular biomarkers for predicting response to tyrosine kinase inhibitors in lung cancer
|
|
MX2012006406A
(es)
|
2009-12-04 |
2012-07-25 |
Genentech Inc |
Anticuerpos multiespecificos, analogos de anticuerpo, composiciones y metodos.
|
|
PE20121384A1
(es)
|
2009-12-08 |
2012-10-13 |
Novartis Ag |
Derivados de sulfonamida heterociclicos
|
|
CU24130B1
(es)
|
2009-12-22 |
2015-09-29 |
Novartis Ag |
Isoquinolinonas y quinazolinonas sustituidas
|
|
US8440693B2
(en)
|
2009-12-22 |
2013-05-14 |
Novartis Ag |
Substituted isoquinolinones and quinazolinones
|
|
EP2348020A1
(en)
|
2009-12-23 |
2011-07-27 |
Esteve Química, S.A. |
Preparation process of erlotinib
|
|
CN102712640A
(zh)
|
2010-01-12 |
2012-10-03 |
弗·哈夫曼-拉罗切有限公司 |
三环杂环化合物、其组合物和应用方法
|
|
WO2011107664A1
(en)
|
2010-03-04 |
2011-09-09 |
Hospital District Of Southwest Finland |
Method for selecting patients for treatment with an egfr inhibitor
|
|
EP2547338A2
(en)
|
2010-03-17 |
2013-01-23 |
F. Hoffmann-La Roche AG |
Imidazopyridine compounds, compositions and methods of use
|
|
WO2011120134A1
(en)
|
2010-03-29 |
2011-10-06 |
Zymeworks, Inc. |
Antibodies with enhanced or suppressed effector function
|
|
MX2012011887A
(es)
|
2010-04-16 |
2012-11-30 |
Genentech Inc |
Foxo 3a como biomarcador predictivo para la eficacia del inhibidor de la via de quinasa pi3k/akt.
|
|
DE202010006543U1
(de)
|
2010-05-07 |
2010-09-09 |
Ratiopharm Gmbh |
Erlotinibresinat
|
|
WO2011146568A1
(en)
|
2010-05-19 |
2011-11-24 |
Genentech, Inc. |
Predicting response to a her inhibitor
|
|
WO2011144059A1
(zh)
|
2010-05-21 |
2011-11-24 |
深圳信立泰药业股份有限公司 |
一种稠环喹唑啉类衍生物及其应用
|
|
WO2011147102A1
(zh)
*
|
2010-05-28 |
2011-12-01 |
翔真生物科技股份有限公司 |
6,7-取代基-4-苯胺类喹唑啉的合成方法
|
|
WO2011162343A1
(ja)
|
2010-06-25 |
2011-12-29 |
エーザイ・アール・アンド・ディー・マネジメント株式会社 |
キナーゼ阻害作用を有する化合物の併用による抗腫瘍剤
|
|
UA112517C2
(uk)
|
2010-07-06 |
2016-09-26 |
Новартіс Аг |
Тетрагідропіридопіримідинові похідні
|
|
WO2012028861A1
(en)
*
|
2010-07-23 |
2012-03-08 |
Generics [Uk] Limited |
Pure erlotinib
|
|
AR082418A1
(es)
|
2010-08-02 |
2012-12-05 |
Novartis Ag |
Formas cristalinas de 1-(4-metil-5-[2-(2,2,2-trifluoro-1,1-dimetil-etil)-piridin-4-il]-tiazol-2-il)-amida de 2-amida del acido (s)-pirrolidin-1,2-dicarboxilico
|
|
EP2616072A1
(en)
|
2010-09-15 |
2013-07-24 |
F.Hoffmann-La Roche Ag |
Azabenzothiazole compounds, compositions and methods of use
|
|
US8946260B2
(en)
|
2010-09-16 |
2015-02-03 |
Novartis Ag |
17α-hydroxylase/C17,20-lyase inhibitors
|
|
IT1402029B1
(it)
|
2010-10-14 |
2013-08-28 |
Italiana Sint Spa |
Procedimento per la preparazione di erlotinib
|
|
US9309322B2
(en)
|
2010-11-12 |
2016-04-12 |
Scott & White Healthcare (Swh) |
Antibodies to tumor endothelial marker 8
|
|
JP2013542966A
(ja)
|
2010-11-19 |
2013-11-28 |
エフ．ホフマン−ラ ロシュ アーゲー |
ピラゾロピリジンならびにｔｙｋ２阻害剤としてのピラゾロピリジン及びそれらの使用
|
|
KR20130105675A
(ko)
|
2010-11-25 |
2013-09-25 |
라티오팜 게엠베하 |
아파티닙의 신규 염 및 다형
|
|
DE102010053124A1
(de)
|
2010-12-01 |
2012-06-06 |
Volkswagen Ag |
Kupplung, insbesondere für ein Getriebe eines Kraftfahrzeuges, vorzugsweise Doppelkupplung für ein automatisches oder automatisiertes Doppelkupplungsgetriebe
|
|
BR112013015449A2
(pt)
|
2010-12-21 |
2016-09-20 |
Novartis Ag |
compostos de bi-heteroarila como inibidores de vps23
|
|
EP2468883A1
(en)
|
2010-12-22 |
2012-06-27 |
Pangaea Biotech S.L. |
Molecular biomarkers for predicting response to tyrosine kinase inhibitors in lung cancer
|
|
WO2012085176A1
(en)
|
2010-12-23 |
2012-06-28 |
F. Hoffmann-La Roche Ag |
Tricyclic pyrazinone compounds, compositions and methods of use thereof as janus kinase inhibitors
|
|
US9134297B2
(en)
|
2011-01-11 |
2015-09-15 |
Icahn School Of Medicine At Mount Sinai |
Method and compositions for treating cancer and related methods
|
|
EA025011B1
(ru)
|
2011-01-31 |
2016-11-30 |
Новартис Аг |
ПУРИНЫ, ПОЛЕЗНЫЕ В КАЧЕСТВЕ ИНГИБИТОРОВ mTOR КИНАЗЫ, ИХ ИСПОЛЬЗОВАНИЕ И ИХ ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ
|
|
US20130324526A1
(en)
|
2011-02-10 |
2013-12-05 |
Novartis Ag |
[1,2,4] triazolo [4,3-b] pyridazine compounds as inhibitors of the c-met tyrosine kinase
|
|
EP2678016B1
(en)
|
2011-02-23 |
2016-08-10 |
Intellikine, LLC |
Heterocyclic compounds and uses thereof
|
|
EP2492688A1
(en)
|
2011-02-23 |
2012-08-29 |
Pangaea Biotech, S.A. |
Molecular biomarkers for predicting response to antitumor treatment in lung cancer
|
|
JP6006242B2
(ja)
|
2011-03-04 |
2016-10-12 |
ニューゲン セラピューティクス， インコーポレイテッド |
アルキン置換キナゾリン化合物および使用方法
|
|
JP5832559B2
(ja)
|
2011-03-10 |
2015-12-16 |
オメロス コーポレーション |
ｅｘｖｉｖｏにおける加速された抗体進化による抗ＦＮ１４モノクローナル抗体の生成
|
|
WO2012129145A1
(en)
|
2011-03-18 |
2012-09-27 |
OSI Pharmaceuticals, LLC |
Nscle combination therapy
|
|
CA2828946C
(en)
|
2011-04-18 |
2016-06-21 |
Eisai R&D Management Co., Ltd. |
Therapeutic agent for tumor
|
|
EP2702173A1
(en)
|
2011-04-25 |
2014-03-05 |
OSI Pharmaceuticals, LLC |
Use of emt gene signatures in cancer drug discovery, diagnostics, and treatment
|
|
GB201106870D0
(en)
|
2011-04-26 |
2011-06-01 |
Univ Belfast |
Marker
|
|
KR20140025492A
(ko)
|
2011-04-28 |
2014-03-04 |
노파르티스 아게 |
17α-히드록실라제/C17,20-리아제 억제제
|
|
WO2012155339A1
(zh)
*
|
2011-05-17 |
2012-11-22 |
江苏康缘药业股份有限公司 |
4-苯胺-6-丁烯酰胺-7-烷醚喹唑啉衍生物及其制备方法和用途
|
|
EP3444363B1
(en)
|
2011-06-03 |
2020-11-25 |
Eisai R&D Management Co., Ltd. |
Biomarkers for prediciting and assessing responsiveness of thyroid and kidney cancer subjects to lenvatinib compounds
|
|
BR112013031201A2
(pt)
|
2011-06-09 |
2017-01-31 |
Novartis Ag |
derivados de sulfonamida heterocíclicos, composição farmacêutica os compreendendo, uso, processo para a fabricação de (r)-n-(4,5-difluoro-6-((2-fluoro-4-iodofenil)amino)benzofuran-7-il)-1-(2,3-di-idroxipropil)ciclopropano-5 1-sulfonamida e kit
|
|
WO2012175520A1
(en)
|
2011-06-20 |
2012-12-27 |
Novartis Ag |
Hydroxy substituted isoquinolinone derivatives
|
|
EP2721007B1
(en)
|
2011-06-20 |
2015-04-29 |
Novartis AG |
Cyclohexyl isoquinolinone compounds
|
|
CN102267952B
(zh)
*
|
2011-06-21 |
2013-12-11 |
天津市汉康医药生物技术有限公司 |
喹唑啉类化合物、其制备方法和用途
|
|
WO2013001445A1
(en)
|
2011-06-27 |
2013-01-03 |
Novartis Ag |
Solid forms and salts of tetrahydro-pyrido-pyrimidine derivatives
|
|
US8575339B2
(en)
*
|
2011-07-05 |
2013-11-05 |
Xueheng Cheng |
Derivatives of erlotinib
|
|
WO2013007765A1
(en)
|
2011-07-13 |
2013-01-17 |
F. Hoffmann-La Roche Ag |
Fused tricyclic compounds for use as inhibitors of janus kinases
|
|
WO2013007768A1
(en)
|
2011-07-13 |
2013-01-17 |
F. Hoffmann-La Roche Ag |
Tricyclic heterocyclic compounds, compositions and methods of use thereof as jak inhibitors
|
|
AU2012295394B2
(en)
|
2011-08-12 |
2016-04-14 |
Omeros Corporation |
Anti-FZD10 monoclonal antibodies and methods for their use
|
|
EP2742040B1
(en)
|
2011-08-12 |
2016-04-06 |
F.Hoffmann-La Roche Ag |
Indazole compounds, compositions and methods of use
|
|
EP3795145A3
(en)
|
2011-08-17 |
2021-06-09 |
Dennis M. Brown |
Compositions and methods to improve the therapeutic benefit of suboptimally administered chemical compounds including substituted hexitols such as dibromodulcitol
|
|
BR112014004762A2
(pt)
|
2011-08-31 |
2018-06-19 |
Genentech Inc |
métodos de determinação da sensibilidade de crescimento de célula tumoral á inibição por um inibidor de quinase de egfr, de identificação de um paciente com câncer que provavelmente irá se beneficiar do tratamento com um inibidor de efgr, de tratamento de um câncer em um paciente, de seleção de uma terapia para um paciente com câncer e de determinação de superexpressão de gene erbb2 em uma célula
|
|
JP5957526B2
(ja)
|
2011-09-15 |
2016-07-27 |
ノバルティス アーゲー |
チロシンキナーゼとしての６−置換３−（キノリン−６−イルチオ）−［１，２，４］トリアゾロ［４，３−ａ］ピラジン
|
|
MX2014002949A
(es)
|
2011-09-20 |
2014-04-30 |
Hoffmann La Roche |
Compuesto de imidazopiridina, composiciones y metodos de uso.
|
|
RU2014110228A
(ru)
|
2011-09-30 |
2015-11-10 |
Дженентек, Инк. |
Диагностические маркеры
|
|
HU230483B1
(hu)
|
2011-10-10 |
2016-07-28 |
Egis Gyógyszergyár Nyrt. |
Erlotinib sók
|
|
US20140309229A1
(en)
|
2011-10-13 |
2014-10-16 |
Bristol-Myers Squibb Company |
Methods for selecting and treating cancer in patients with igf-1r/ir inhibitors
|
|
PL2771342T3
(pl)
|
2011-10-28 |
2016-11-30 |
|
Nowe pochodne puryny i ich zastosowanie w leczeniu chorób
|
|
WO2013080141A1
(en)
|
2011-11-29 |
2013-06-06 |
Novartis Ag |
Pyrazolopyrrolidine compounds
|
|
US9408885B2
(en)
|
2011-12-01 |
2016-08-09 |
Vib Vzw |
Combinations of therapeutic agents for treating melanoma
|
|
WO2013093850A1
(en)
|
2011-12-22 |
2013-06-27 |
Novartis Ag |
Quinoline derivatives
|
|
JO3398B1
(ar)
|
2011-12-22 |
2019-10-20 |
Novartis Ag |
مشتقات 2،3- ثانى هيدرو- بنزو[1,4] أوكسازين والمركبات المتعلقة بها كمثبطات كيناز فسفواينوسيتيد-3 (pi3k) لمعالجة على سبيل المثال التهاب المفاصل الروماتيدي
|
|
WO2013096049A1
(en)
|
2011-12-23 |
2013-06-27 |
Novartis Ag |
Compounds for inhibiting the interaction of bcl2 with binding partners
|
|
MX2014007731A
(es)
|
2011-12-23 |
2015-01-12 |
Novartis Ag |
Compuestos para inhibir la interaccion de bcl2 con los componentes de enlace.
|
|
CN104125954A
(zh)
|
2011-12-23 |
2014-10-29 |
诺华股份有限公司 |
用于抑制bcl2与结合配偶体相互作用的化合物
|
|
US20140357666A1
(en)
|
2011-12-23 |
2014-12-04 |
Novartis Ag |
Compounds for inhibiting the interaction of bcl2 with binding partners
|
|
MX2014007725A
(es)
|
2011-12-23 |
2015-01-12 |
Novartis Ag |
Compuestos para inhibir la interaccion de bcl2 con los componentes de enlace.
|
|
US8815926B2
(en)
|
2012-01-26 |
2014-08-26 |
Novartis Ag |
Substituted pyrrolo[3,4-D]imidazoles for the treatment of MDM2/4 mediated diseases
|
|
AU2013229786B2
(en)
|
2012-03-08 |
2017-06-22 |
Halozyme, Inc. |
Conditionally active anti-epidermal growth factor receptor antibodies and methods of use thereof
|
|
WO2013148315A1
(en)
|
2012-03-27 |
2013-10-03 |
Genentech, Inc. |
Diagnosis and treatments relating to her3 inhibitors
|
|
RU2660354C2
(ru)
|
2012-04-03 |
2018-07-05 |
Новартис Аг |
Комбинированные продукты, содержащие ингибиторы тирозинкиназ, и их применение
|
|
WO2013152252A1
(en)
|
2012-04-06 |
2013-10-10 |
OSI Pharmaceuticals, LLC |
Combination anti-cancer therapy
|
|
US10213432B2
(en)
|
2012-05-16 |
2019-02-26 |
Novartis Ag |
Dosage regimen for a PI-3 kinase inhibitor
|
|
EP2855483B1
(en)
|
2012-05-24 |
2017-10-25 |
Novartis AG |
Pyrrolopyrrolidinone compounds
|
|
CN104582732A
(zh)
|
2012-06-15 |
2015-04-29 |
布里格姆及妇女医院股份有限公司 |
治疗癌症的组合物及其制造方法
|
|
WO2013190089A1
(en)
|
2012-06-21 |
2013-12-27 |
Pangaea Biotech, S.L. |
Molecular biomarkers for predicting outcome in lung cancer
|
|
WO2014037961A1
(en)
|
2012-09-04 |
2014-03-13 |
Shilpa Medicare Limited |
Crystalline erlotinib hydrochloride process
|
|
TW201422625A
(zh)
|
2012-11-26 |
2014-06-16 |
Novartis Ag |
二氫－吡啶并－□衍生物之固體形式
|
|
KR20150098605A
(ko)
|
2012-12-21 |
2015-08-28 |
에자이 알앤드디 매니지먼트 가부시키가이샤 |
퀴놀린 유도체의 비정질 형태 및 그의 제조방법
|
|
EP2948451B1
(en)
|
2013-01-22 |
2017-07-12 |
Novartis AG |
Substituted purinone compounds
|
|
EP2948453B1
(en)
|
2013-01-22 |
2017-08-02 |
Novartis AG |
Pyrazolo[3,4-d]pyrimidinone compounds as inhibitors of the p53/mdm2 interaction
|
|
WO2014118112A1
(en)
|
2013-01-29 |
2014-08-07 |
Synthon B.V. |
Pharmaceutical composition comprising erlotinib hydrochloride
|
|
WO2014128612A1
(en)
|
2013-02-20 |
2014-08-28 |
Novartis Ag |
Quinazolin-4-one derivatives
|
|
JP6255038B2
(ja)
|
2013-02-26 |
2017-12-27 |
トリアクト セラピューティクス，インク． |
癌治療
|
|
MX2015011898A
(es)
|
2013-03-13 |
2016-05-05 |
Genentech Inc |
Compuestos de pirazolo y usos de los mismos.
|
|
EP2968340A4
(en)
|
2013-03-15 |
2016-08-10 |
Intellikine Llc |
COMBINING KINASE INHIBITORS AND USES THEREOF
|
|
WO2014147246A1
(en)
|
2013-03-21 |
2014-09-25 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Method and pharmaceutical composition for use in the treatment of chronic liver diseases associated with a low hepcidin expression
|
|
WO2014155268A2
(en)
|
2013-03-25 |
2014-10-02 |
Novartis Ag |
Fgf-r tyrosine kinase activity inhibitors - use in diseases associated with lack of or reduced snf5 activity
|
|
EP2997377B1
(en)
|
2013-05-14 |
2018-07-18 |
Eisai R&D Management Co., Ltd. |
Biomarkers for predicting and assessing responsiveness of endometrial cancer subjects to lenvatinib compounds
|
|
US20150018376A1
(en)
|
2013-05-17 |
2015-01-15 |
Novartis Ag |
Pyrimidin-4-yl)oxy)-1h-indole-1-carboxamide derivatives and use thereof
|
|
UY35675A
(es)
|
2013-07-24 |
2015-02-27 |
Novartis Ag |
Derivados sustituidos de quinazolin-4-ona
|
|
WO2015022664A1
(en)
|
2013-08-14 |
2015-02-19 |
Novartis Ag |
Compounds and compositions as inhibitors of mek
|
|
US9227969B2
(en)
|
2013-08-14 |
2016-01-05 |
Novartis Ag |
Compounds and compositions as inhibitors of MEK
|
|
WO2015022663A1
(en)
|
2013-08-14 |
2015-02-19 |
Novartis Ag |
Compounds and compositions as inhibitors of mek
|
|
CN105611933B
(zh)
|
2013-09-05 |
2019-01-25 |
基因泰克公司 |
抗增生性化合物
|
|
US9381246B2
(en)
|
2013-09-09 |
2016-07-05 |
Triact Therapeutics, Inc. |
Cancer therapy
|
|
CN105764924A
(zh)
|
2013-09-12 |
2016-07-13 |
哈洛齐梅公司 |
修饰的抗表皮生长因子受体抗体及其使用方法
|
|
ES2914176T3
(es)
|
2013-09-17 |
2022-06-07 |
Obi Pharma Inc |
Composiciones de una vacuna glucídica para inducir respuestas inmunitarias y usos de las mismas en el tratamiento de cáncer
|
|
MX2016003456A
(es)
|
2013-09-22 |
2017-05-25 |
Calitor Sciences Llc |
Compuestos aminopirimidina sustituidos y metodos de uso.
|
|
TW201605857A
(zh)
|
2013-10-03 |
2016-02-16 |
赫孚孟拉羅股份公司 |
Ｃｄｋ８之醫療性抑制劑及其用途
|
|
TW201605450A
(zh)
|
2013-12-03 |
2016-02-16 |
諾華公司 |
Ｍｄｍ２抑制劑與ＢＲＡＦ抑制劑之組合及其用途
|
|
PL3076969T3
(pl)
|
2013-12-06 |
2022-01-17 |
Novartis Ag |
Schemat dawkowania selektywnego inhibitora 3-kinazy fosfatydynozytolu alfa-izoformy
|
|
EP3083687A2
(en)
|
2013-12-17 |
2016-10-26 |
F. Hoffmann-La Roche AG |
Combination therapy comprising ox40 binding agonists and pd-1 axis binding antagonists
|
|
FI3083686T4
(fi)
|
2013-12-17 |
2023-05-09 |
|
Menetelmiä syöpien hoitamiseksi käyttäen pd-1-akselia sitovia antagonisteja ja taksaaneja
|
|
US9242965B2
(en)
|
2013-12-31 |
2016-01-26 |
Boehringer Ingelheim International Gmbh |
Process for the manufacture of (E)-4-N,N-dialkylamino crotonic acid in HX salt form and use thereof for synthesis of EGFR tyrosine kinase inhibitors
|
|
WO2015145388A2
(en)
|
2014-03-27 |
2015-10-01 |
Novartis Ag |
Methods of treating colorectal cancers harboring upstream wnt pathway mutations
|
|
US9394281B2
(en)
|
2014-03-28 |
2016-07-19 |
Calitor Sciences, Llc |
Substituted heteroaryl compounds and methods of use
|
|
RU2016142476A
(ru)
|
2014-03-31 |
2018-05-07 |
Дженентек, Инк. |
Комбинированная терапия, включающая антиангиогенезные агенты и агонисты, связывающие ох40
|
|
DK3126394T3
(da)
|
2014-03-31 |
2020-01-13 |
Hoffmann La Roche |
Anti-OX40-antistoffer og fremgangsmåder til anvendelse
|
|
WO2015153345A1
(en)
|
2014-04-03 |
2015-10-08 |
Invictus Oncology Pvt. Ltd. |
Supramolecular combinatorial therapeutics
|
|
US20170027940A1
(en)
|
2014-04-10 |
2017-02-02 |
Stichting Het Nederlands Kanker Instituut |
Method for treating cancer
|
|
WO2016011658A1
(en)
|
2014-07-25 |
2016-01-28 |
Novartis Ag |
Combination therapy
|
|
US10195208B2
(en)
|
2014-07-31 |
2019-02-05 |
Novartis Ag |
Combination therapy
|
|
HUE059606T2
(hu)
|
2014-08-28 |
2022-11-28 |
Eisai R&D Man Co Ltd |
Nagy tisztaságú kinolinszármazék és eljárás elõállítására
|
|
CN107074823B
(zh)
|
2014-09-05 |
2021-05-04 |
基因泰克公司 |
治疗性化合物及其用途
|
|
WO2016044694A1
(en)
|
2014-09-19 |
2016-03-24 |
Genentech, Inc. |
Use of cbp/ep300 and bet inhibitors for treatment of cancer
|
|
JP6783230B2
(ja)
|
2014-10-10 |
2020-11-11 |
ジェネンテック， インコーポレイテッド |
ヒストンデメチラーゼのインヒビターとしてのピロリドンアミド化合物
|
|
US20170252335A1
(en)
|
2014-10-17 |
2017-09-07 |
Novartis Ag |
Combination of Ceritinib with an EGFR Inhibitor
|
|
CA2908441A1
(en)
|
2014-10-28 |
2016-04-28 |
Cerbios-Pharma Sa |
Process for the preparation of erlotinib
|
|
BR112017009151A2
(pt)
|
2014-11-03 |
2018-03-06 |
Genentech, Inc. |
ensaios para detectar subgrupos imunológicos de célula t e métodos de uso dos mesmos
|
|
US20160160290A1
(en)
|
2014-11-03 |
2016-06-09 |
Genentech, Inc. |
Methods and biomarkers for predicting efficacy and evaluation of an ox40 agonist treatment
|
|
JP2017534633A
(ja)
|
2014-11-06 |
2017-11-24 |
ジェネンテック， インコーポレイテッド |
Ｏｘ４０結合アゴニスト及びｔｉｇｉｔ阻害剤を含む組み合わせ療法
|
|
MA40940A
(fr)
|
2014-11-10 |
2017-09-19 |
Constellation Pharmaceuticals Inc |
Pyrrolopyridines substituées utilisées en tant qu'inhibiteurs de bromodomaines
|
|
MA40943A
(fr)
|
2014-11-10 |
2017-09-19 |
Constellation Pharmaceuticals Inc |
Pyrrolopyridines substituées utilisées en tant qu'inhibiteurs de bromodomaines
|
|
CN107108613B
(zh)
|
2014-11-10 |
2020-02-25 |
基因泰克公司 |
布罗莫结构域抑制剂及其用途
|
|
AU2015350242A1
(en)
|
2014-11-17 |
2017-06-29 |
Genentech, Inc. |
Combination therapy comprising OX40 binding agonists and PD-1 axis binding antagonists
|
|
WO2016082879A1
(en)
*
|
2014-11-27 |
2016-06-02 |
Synthon B.V. |
Pharmaceutical composition comprising erlotinib hydrochloride
|
|
US9763922B2
(en)
|
2014-11-27 |
2017-09-19 |
Genentech, Inc. |
Therapeutic compounds and uses thereof
|
|
MX2017006864A
(es)
|
2014-12-23 |
2017-08-28 |
Genentech Inc |
Composiciones y métodos para tratar y diagnosticar cánceres resistentes a la quimioterapia.
|
|
KR20170095893A
(ko)
|
2014-12-24 |
2017-08-23 |
제넨테크, 인크. |
방광암에 대한 치료, 진단, 및 예후 방법
|
|
EP3240908A2
(en)
|
2014-12-30 |
2017-11-08 |
F. Hoffmann-La Roche AG |
Methods and compositions for prognosis and treatment of cancers
|
|
EP3242875B1
(en)
|
2015-01-09 |
2022-02-23 |
Genentech, Inc. |
4,5-dihydroimidazole derivatives and their use as histone demethylase (kdm2b) inhibitors
|
|
JP6659703B2
(ja)
|
2015-01-09 |
2020-03-04 |
ジェネンテック， インコーポレイテッド |
ピリダジノン誘導体および癌の処置におけるそれらの使用
|
|
WO2016112284A1
(en)
|
2015-01-09 |
2016-07-14 |
Genentech, Inc. |
(piperidin-3-yl)(naphthalen-2-yl)methanone derivatives and related compounds as inhibitors of the histone demethylase kdm2b for the treatment of cancer
|
|
WO2016123391A1
(en)
|
2015-01-29 |
2016-08-04 |
Genentech, Inc. |
Therapeutic compounds and uses thereof
|
|
EP3250552B1
(en)
|
2015-01-30 |
2019-03-27 |
Genentech, Inc. |
Therapeutic compounds and uses thereof
|
|
MA41598A
(fr)
|
2015-02-25 |
2018-01-02 |
Constellation Pharmaceuticals Inc |
Composés thérapeutiques de pyridazine et leurs utilisations
|
|
AU2016224583B2
(en)
|
2015-02-25 |
2021-06-03 |
Eisai R&D Management Co., Ltd. |
Method for suppressing bitterness of quinoline derivative
|
|
CN104725327B
(zh)
*
|
2015-03-03 |
2017-08-25 |
山东大学 |
一种盐酸厄洛替尼的环保制备方法
|
|
AU2015384801B2
(en)
|
2015-03-04 |
2022-01-06 |
Eisai R&D Management Co., Ltd. |
Combination of a PD-1 antagonist and a VEGFR/FGFR/RET tyrosine kinase inhibitor for treating cancer
|
|
KR20180002653A
(ko)
|
2015-04-07 |
2018-01-08 |
제넨테크, 인크. |
효능작용 활성을 갖는 항원 결합 복합체 및 사용 방법
|
|
CN107667119A
(zh)
|
2015-05-12 |
2018-02-06 |
豪夫迈·罗氏有限公司 |
用于癌症的治疗和诊断方法
|
|
ES2789500T5
(es)
|
2015-05-29 |
2023-09-20 |
Hoffmann La Roche |
Procedimientos terapéuticos y de diagnóstico para el cáncer
|
|
EP3303399A1
(en)
|
2015-06-08 |
2018-04-11 |
H. Hoffnabb-La Roche Ag |
Methods of treating cancer using anti-ox40 antibodies
|
|
MX2017015937A
(es)
|
2015-06-08 |
2018-12-11 |
Genentech Inc |
Métodos de tratamiento del cáncer con anticuerpos anti-ox40 y antagonistas de unión al eje de pd-1.
|
|
JP6757959B2
(ja)
|
2015-06-16 |
2020-09-23 |
株式会社 ＰＲＩＳＭ ＢｉｏＬａｂ |
抗がん剤
|
|
IL256080B2
(en)
|
2015-06-17 |
2025-06-01 |
Genentech Inc |
Methods of treating locally advanced or metastatic breast cancers using pd-1 axis binding antagonists and taxanes
|
|
CN105017162B
(zh)
*
|
2015-06-26 |
2017-10-27 |
陕西师范大学 |
4‑对丙烯基苯氨基喹唑啉衍生物及其在制备抗肿瘤药物中的应用
|
|
CA2994925C
(en)
|
2015-08-20 |
2023-08-29 |
Eisai R&D Management Co., Ltd. |
Tumor therapeutic agent
|
|
ES2862727T3
(es)
|
2015-08-26 |
2021-10-07 |
Fundacion Del Sector Publico Estatal Centro Nac De Investigaciones Oncologicas Carlos Iii F S P Cnio |
Compuestos tricíclicos condensados como inhibidores de proteínas quinasas
|
|
JP2018526376A
(ja)
|
2015-08-28 |
2018-09-13 |
ノバルティス アーゲー |
がんの治療または予防のための（ａ）サイクリン依存性キナーゼ４／６（ｃｄｋ４／６）阻害剤のｌｅｅ０１１（＝リボシクリブ）および（ｂ）上皮成長因子受容体（ｅｇｆｒ）阻害剤のエルロチニブを含む医薬組み合わせ物
|
|
JP2018532990A
(ja)
|
2015-09-04 |
2018-11-08 |
オービーアイ ファーマ，インコーポレイテッド |
グリカンアレイおよび使用の方法
|
|
EP3347097B1
(en)
|
2015-09-11 |
2021-02-24 |
Sunshine Lake Pharma Co., Ltd. |
Substituted aminopyrimidine derivatives as modulators of the kinases jak, flt3 and aurora
|
|
BR112018005862A2
(pt)
|
2015-09-25 |
2018-10-16 |
Genentech, Inc. |
anticorpos, anticorpos isolados, polinucleotídeo, vetor, célula hospedeira, método de produção do anticorpo, imunoconjugado, composição, usos dos anticorpos, métodos para tratar ou retardar a progressão de um câncer e de uma doença e para aumentar, potencializar ou estimular uma resposta ou função imune e kit
|
|
CN108472289A
(zh)
|
2015-11-02 |
2018-08-31 |
诺华股份有限公司 |
磷脂酰肌醇3-激酶抑制剂的给药方案
|
|
MY196817A
(en)
|
2015-12-16 |
2023-05-03 |
Genentech Inc |
Process for the preparation of tricyclic pi3k inhibitor compounds and methods for using the same for the treatment of cancer
|
|
KR20180097615A
(ko)
|
2016-01-08 |
2018-08-31 |
에프. 호프만-라 로슈 아게 |
Pd-1 축 결합 길항물질 및 항-cea/항-cd3 이중특이성 항체를 사용하는 cea-양성 암의 치료 방법
|
|
WO2017151502A1
(en)
|
2016-02-29 |
2017-09-08 |
Genentech, Inc. |
Therapeutic and diagnostic methods for cancer
|
|
JP2019513144A
(ja)
|
2016-03-29 |
2019-05-23 |
オービーアイ ファーマ，インコーポレイテッド |
抗体、医薬組成物及び方法
|
|
US10980894B2
(en)
|
2016-03-29 |
2021-04-20 |
Obi Pharma, Inc. |
Antibodies, pharmaceutical compositions and methods
|
|
CN109154027A
(zh)
|
2016-04-15 |
2019-01-04 |
豪夫迈·罗氏有限公司 |
用于监测和治疗癌症的方法
|
|
CN109072311A
(zh)
|
2016-04-15 |
2018-12-21 |
豪夫迈·罗氏有限公司 |
用于癌症的诊断和治疗方法
|
|
PL3443350T3
(pl)
|
2016-04-15 |
2021-05-31 |
F. Hoffmann-La Roche Ag |
Sposoby monitorowania i leczenia nowotworu
|
|
MY200886A
(en)
|
2016-04-22 |
2024-01-22 |
Obi Pharma Inc |
Cancer Immunotherapy by Immune Activation or Immune Modulation Via Globo Series Antigens
|
|
EP3454863A1
(en)
|
2016-05-10 |
2019-03-20 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Combinations therapies for the treatment of cancer
|
|
MA45122A
(fr)
|
2016-05-24 |
2019-04-10 |
Constellation Pharmaceuticals Inc |
Inhibiteurs hétérocycliques de cbp/ep300 et leur utilisation dans le traitement du cancer
|
|
CN109476663B
(zh)
|
2016-05-24 |
2021-11-09 |
基因泰克公司 |
用于治疗癌症的吡唑并吡啶衍生物
|
|
WO2017214373A1
(en)
|
2016-06-08 |
2017-12-14 |
Genentech, Inc. |
Diagnostic and therapeutic methods for cancer
|
|
US11365256B2
(en)
|
2016-06-08 |
2022-06-21 |
Xencor, Inc. |
Methods and compositions for inhibiting CD32B expressing cells in IGG4-related diseases
|
|
JP2019527690A
(ja)
|
2016-07-27 |
2019-10-03 |
オービーアイ ファーマ，インコーポレイテッド |
免疫原性／治療用グリカン組成物およびその使用
|
|
JP7121724B2
(ja)
|
2016-07-29 |
2022-08-18 |
オービーアイ ファーマ，インコーポレイテッド |
ヒト抗体、医薬組成物及び方法
|
|
CN109963871A
(zh)
|
2016-08-05 |
2019-07-02 |
豪夫迈·罗氏有限公司 |
具有激动活性的多价及多表位抗体以及使用方法
|
|
EP3497129A1
(en)
|
2016-08-08 |
2019-06-19 |
H. Hoffnabb-La Roche Ag |
Therapeutic and diagnostic methods for cancer
|
|
WO2018060833A1
(en)
|
2016-09-27 |
2018-04-05 |
Novartis Ag |
Dosage regimen for alpha-isoform selective phosphatidylinositol 3-kinase inhibitor alpelisib
|
|
CA3038712A1
(en)
|
2016-10-06 |
2018-04-12 |
Genentech, Inc. |
Therapeutic and diagnostic methods for cancer
|
|
WO2018078143A1
(en)
|
2016-10-28 |
2018-05-03 |
MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. |
Means and methods for determining efficacy of anti-egfr inhibitors in colorectal cancer (crc) therapy
|
|
CN110267678A
(zh)
|
2016-10-29 |
2019-09-20 |
霍夫曼-拉罗奇有限公司 |
抗mic抗体和使用方法
|
|
JP2019535731A
(ja)
|
2016-11-21 |
2019-12-12 |
オービーアイ ファーマ，インコーポレイテッド |
コンジュゲートさせた生物学的分子、医薬組成物及び方法
|
|
JOP20190154B1
(ar)
|
2016-12-22 |
2022-09-15 |
Amgen Inc |
بنز أيزو ثيازول، أيزو ثيازولو [3، 4-b] بيريدين، كينازولين، فثالازين، بيريدو [2، 3-d] بيريدازين ومشتقات بيريدو [2، 3-d] بيريميدين على هيئة مثبطات kras g12c لمعالجة سرطان الرئة، أو سرطان البنكرياس أو سرطان القولون والمستقيم
|
|
BR112019014127A2
(pt)
|
2017-02-08 |
2020-02-11 |
Eisai R&D Management Co., Ltd. |
Composição farmacêutica para tratamento de tumores
|
|
AU2018228873A1
(en)
|
2017-03-01 |
2019-08-29 |
Genentech, Inc. |
Diagnostic and therapeutic methods for cancer
|
|
CN106928069B
(zh)
*
|
2017-03-21 |
2019-03-19 |
上海玉函化工有限公司 |
一种4,5-二(2-甲氧基乙氧基)-2-硝基苯甲酸乙酯的制备方法
|
|
MX2019012187A
(es)
|
2017-04-13 |
2019-11-25 |
Hoffmann La Roche |
Un inmunoconjugado de interleuquina-2, un agonista de cd40 y opcionalmente un antagonista de union al eje pd-1 para uso en metodos para tratar cancer.
|
|
MX2019013014A
(es)
|
2017-05-16 |
2020-08-06 |
Eisai R&D Man Co Ltd |
Tratamiento de carcinoma hepatocelular.
|
|
JOP20190272A1
(ar)
|
2017-05-22 |
2019-11-21 |
Amgen Inc |
مثبطات kras g12c وطرق لاستخدامها
|
|
CN107200715B
(zh)
*
|
2017-06-22 |
2020-05-29 |
陕西师范大学 |
喹唑啉衍生物及其在制备抗肿瘤药物中的应用
|
|
EP3655034A1
(en)
|
2017-07-21 |
2020-05-27 |
Genentech, Inc. |
Therapeutic and diagnostic methods for cancer
|
|
JP2020530297A
(ja)
|
2017-08-11 |
2020-10-22 |
ジェネンテック， インコーポレイテッド |
抗ｃｄ８抗体及びその使用
|
|
ES2985118T3
(es)
|
2017-09-08 |
2024-11-04 |
Amgen Inc |
Inhibidores de KRAS G12C y métodos de uso de los mismos
|
|
WO2019051296A1
(en)
|
2017-09-08 |
2019-03-14 |
Genentech, Inc. |
DIAGNOSTIC AND THERAPEUTIC METHODS OF CANCER
|
|
EP3687981A4
(en)
*
|
2017-09-26 |
2021-03-31 |
The Regents of the University of California |
CANCER COMPOSITIONS AND TREATMENT METHODS
|
|
US11369608B2
(en)
|
2017-10-27 |
2022-06-28 |
University Of Virginia Patent Foundation |
Compounds and methods for regulating, limiting, or inhibiting AVIL expression
|
|
KR20200075860A
(ko)
|
2017-11-06 |
2020-06-26 |
제넨테크, 인크. |
암의 진단 및 치료 방법
|
|
JP7254076B2
(ja)
|
2017-11-19 |
2023-04-07 |
サンシャイン・レイク・ファーマ・カンパニー・リミテッド |
置換ヘテロアリール化合物及び使用方法
|
|
EP3740756A4
(en)
|
2018-01-15 |
2021-10-27 |
Epiaxis Therapeutics Pty Ltd |
AGENTS AND METHODS FOR PREDICTING THE THERAPEUTIC RESPONSE
|
|
WO2019143874A1
(en)
|
2018-01-20 |
2019-07-25 |
Sunshine Lake Pharma Co., Ltd. |
Substituted aminopyrimidine compounds and methods of use
|
|
AU2019212800B2
(en)
|
2018-01-26 |
2024-05-23 |
Exelixis, Inc. |
Compounds for the treatment of kinase-dependent disorders
|
|
SG11202006921PA
(en)
|
2018-01-26 |
2020-08-28 |
Exelixis Inc |
Compounds for the treatment of kinase-dependent disorders
|
|
EP3743068A1
(en)
|
2018-01-26 |
2020-12-02 |
Exelixis, Inc. |
Compounds for the treatment of kinase-dependent disorders
|
|
TWI660728B
(zh)
*
|
2018-02-09 |
2019-06-01 |
國立交通大學 |
胺基喹唑啉衍生物及其醫藥組合物與用途
|
|
EP3759141A1
(en)
|
2018-02-26 |
2021-01-06 |
F. Hoffmann-La Roche AG |
Dosing for treatment with anti-tigit and anti-pd-l1 antagonist antibodies
|
|
WO2019213526A1
(en)
|
2018-05-04 |
2019-11-07 |
Amgen Inc. |
Kras g12c inhibitors and methods of using the same
|
|
JP7266043B2
(ja)
|
2018-05-04 |
2023-04-27 |
アムジエン・インコーポレーテツド |
ＫＲａｓ Ｇ１２Ｃ阻害剤及びそれを使用する方法
|
|
CA3099045A1
(en)
|
2018-05-10 |
2019-11-14 |
Amgen Inc. |
Kras g12c inhibitors for the treatment of cancer
|
|
US20210363590A1
(en)
|
2018-05-21 |
2021-11-25 |
Nanostring Technologies, Inc. |
Molecular gene signatures and methods of using same
|
|
AU2019278998B2
(en)
|
2018-06-01 |
2023-11-09 |
Amgen Inc. |
KRAS G12C inhibitors and methods of using the same
|
|
WO2019241157A1
(en)
|
2018-06-11 |
2019-12-19 |
Amgen Inc. |
Kras g12c inhibitors for treating cancer
|
|
JP7369719B2
(ja)
|
2018-06-12 |
2023-10-26 |
アムジエン・インコーポレーテツド |
ＫＲａｓ Ｇ１２Ｃ阻害剤及びそれを使用する方法
|
|
SG11202012446UA
(en)
|
2018-06-23 |
2021-01-28 |
Genentech Inc |
Methods of treating lung cancer with a pd-1 axis binding antagonist, a platinum agent, and a topoisomerase ii inhibitor
|
|
TW202504930A
(zh)
|
2018-06-27 |
2025-02-01 |
台灣浩鼎生技股份有限公司 |
用於糖蛋白工程的糖苷合成酶變體及其使用方法
|
|
CN110642796B
(zh)
*
|
2018-06-27 |
2023-03-17 |
烟台药物研究所 |
一种喹唑啉类衍生物及其应用
|
|
US20200171146A1
(en)
|
2018-07-18 |
2020-06-04 |
Genentech, Inc. |
Methods of treating lung cancer with a pd-1 axis binding antagonist, an antimetabolite, and a platinum agent
|
|
CN112805267B
(zh)
|
2018-09-03 |
2024-03-08 |
豪夫迈·罗氏有限公司 |
用作tead调节剂的甲酰胺和磺酰胺衍生物
|
|
JP2022501332A
(ja)
|
2018-09-19 |
2022-01-06 |
ジェネンテック， インコーポレイテッド |
膀胱がんの治療方法および診断方法
|
|
PL3857230T3
(pl)
|
2018-09-21 |
2023-10-16 |
F. Hoffmann-La Roche Ag |
Sposoby diagnostyczne dla potrójnie ujemnego raka piersi
|
|
AU2019346550A1
(en)
|
2018-09-25 |
2021-04-22 |
Black Diamond Therapeutics, Inc. |
Quinazoline derivatives as tyrosine kinase inhibitor, compositions, methods of making them and their use
|
|
AU2019352741A1
(en)
|
2018-10-04 |
2021-05-06 |
Assistance Publique-Hôpitaux De Paris (Aphp) |
EGFR inhibitors for treating keratodermas
|
|
WO2020077409A1
(en)
|
2018-10-17 |
2020-04-23 |
The University Of Queensland |
Epigenetic biomarker and uses therefor
|
|
EP3867646A1
(en)
|
2018-10-18 |
2021-08-25 |
F. Hoffmann-La Roche AG |
Diagnostic and therapeutic methods for sarcomatoid kidney cancer
|
|
JP7516029B2
(ja)
|
2018-11-16 |
2024-07-16 |
アムジエン・インコーポレーテツド |
Ｋｒａｓ ｇ１２ｃ阻害剤化合物の重要な中間体の改良合成法
|
|
JP7377679B2
(ja)
|
2018-11-19 |
2023-11-10 |
アムジエン・インコーポレーテツド |
がん治療のためのｋｒａｓｇ１２ｃ阻害剤及び１種以上の薬学的に活性な追加の薬剤を含む併用療法
|
|
US11053226B2
(en)
|
2018-11-19 |
2021-07-06 |
Amgen Inc. |
KRAS G12C inhibitors and methods of using the same
|
|
CR20210387A
(es)
|
2018-12-20 |
2021-08-19 |
Amgen Inc |
Inhibidores de kif18a
|
|
JP7676308B2
(ja)
|
2018-12-20 |
2025-05-14 |
アムジエン・インコーポレーテツド |
Ｋｉｆ１８ａ阻害剤として有用なヘテロアリールアミド
|
|
AU2019403488B2
(en)
|
2018-12-20 |
2025-07-24 |
Amgen Inc. |
KIF18A inhibitors
|
|
MA54546A
(fr)
|
2018-12-20 |
2022-03-30 |
Amgen Inc |
Amides d'hétéroaryle utiles en tant qu'inhibiteurs de kif18a
|
|
KR20210107069A
(ko)
|
2018-12-21 |
2021-08-31 |
다이이찌 산쿄 가부시키가이샤 |
항체-약물 컨쥬게이트와 키나아제 저해제의 조합
|
|
EP3921443A1
(en)
|
2019-02-08 |
2021-12-15 |
F. Hoffmann-La Roche AG |
Diagnostic and therapeutic methods for cancer
|
|
MX2021010313A
(es)
|
2019-02-27 |
2021-09-23 |
Genentech Inc |
Dosificacion para el tratamiento con anticuerpos anti-tigit y anti-cd20 o anti-cd38.
|
|
JP7520389B2
(ja)
|
2019-02-27 |
2024-07-23 |
エピアクシス セラピューティクス プロプライエタリー リミテッド |
Ｔ細胞機能を評価して治療法に対する応答を予測するための方法および薬剤
|
|
US20230096028A1
(en)
|
2019-03-01 |
2023-03-30 |
Revolution Medicines, Inc. |
Bicyclic heterocyclyl compounds and uses thereof
|
|
KR20210146287A
(ko)
|
2019-03-01 |
2021-12-03 |
레볼루션 메디슨즈, 인크. |
이환식 헤테로아릴 화합물 및 이의 용도
|
|
WO2020223233A1
(en)
|
2019-04-30 |
2020-11-05 |
Genentech, Inc. |
Prognostic and therapeutic methods for colorectal cancer
|
|
JP2022530674A
(ja)
|
2019-05-03 |
2022-06-30 |
ジェネンテック， インコーポレイテッド |
抗ｐｄ－ｌ１抗体を用いたがんの処置方法
|
|
EP3738593A1
(en)
|
2019-05-14 |
2020-11-18 |
Amgen, Inc |
Dosing of kras inhibitor for treatment of cancers
|
|
KR20220011670A
(ko)
|
2019-05-21 |
2022-01-28 |
암젠 인크 |
고체 상태 형태
|
|
CN112300279A
(zh)
|
2019-07-26 |
2021-02-02 |
上海复宏汉霖生物技术股份有限公司 |
针对抗cd73抗体和变体的方法和组合物
|
|
WO2021026099A1
(en)
|
2019-08-02 |
2021-02-11 |
Amgen Inc. |
Kif18a inhibitors
|
|
WO2021026098A1
(en)
|
2019-08-02 |
2021-02-11 |
Amgen Inc. |
Kif18a inhibitors
|
|
US20220281843A1
(en)
|
2019-08-02 |
2022-09-08 |
Amgen Inc. |
Kif18a inhibitors
|
|
US20220372018A1
(en)
|
2019-08-02 |
2022-11-24 |
Amgen Inc. |
Kif18a inhibitors
|
|
PE20221449A1
(es)
|
2019-09-04 |
2022-09-21 |
Genentech Inc |
Agentes de union a cd8 y usos de los mismos
|
|
TW202126651A
(zh)
|
2019-09-26 |
2021-07-16 |
美商艾克塞里克斯公司 |
吡啶酮化合物及使用方法
|
|
WO2021062085A1
(en)
|
2019-09-27 |
2021-04-01 |
Genentech, Inc. |
Dosing for treatment with anti-tigit and anti-pd-l1 antagonist antibodies
|
|
WO2021081212A1
(en)
|
2019-10-24 |
2021-04-29 |
Amgen Inc. |
Pyridopyrimidine derivatives useful as kras g12c and kras g12d inhibitors in the treatment of cancer
|
|
EP4051674A1
(en)
|
2019-10-29 |
2022-09-07 |
F. Hoffmann-La Roche AG |
Bifunctional compounds for the treatment of cancer
|
|
MX2022005357A
(es)
|
2019-11-04 |
2022-06-02 |
Revolution Medicines Inc |
Inhibidores de ras.
|
|
US11566007B2
(en)
|
2019-11-04 |
2023-01-31 |
Revolution Medicines, Inc. |
Ras inhibitors
|
|
CA3160142A1
(en)
|
2019-11-04 |
2021-05-14 |
Revolution Medicines, Inc. |
Ras inhibitors
|
|
EP4055388A1
(en)
|
2019-11-06 |
2022-09-14 |
Genentech, Inc. |
Diagnostic and therapeutic methods for treatment of hematologic cancers
|
|
PH12022551102A1
(en)
|
2019-11-08 |
2023-11-20 |
Revolution Medicines Inc |
Bicyclic heteroaryl compounds and uses thereof
|
|
US20210161897A1
(en)
|
2019-11-12 |
2021-06-03 |
Astrazeneca Ab |
Epidermal growth factor receptor tyrosine kinase inhibitors for the treatment of cancer
|
|
AU2020381458A1
(en)
|
2019-11-13 |
2022-05-12 |
Genentech, Inc. |
Therapeutic compounds and methods of use
|
|
IL292315A
(en)
|
2019-11-14 |
2022-06-01 |
Amgen Inc |
Improved synthesis of kras g12c inhibitor compound
|
|
AR120456A1
(es)
|
2019-11-14 |
2022-02-16 |
Amgen Inc |
Síntesis mejorada del compuesto inhibidor de g12c de kras
|
|
JP2023505100A
(ja)
|
2019-11-27 |
2023-02-08 |
レボリューション メディシンズ インコーポレイテッド |
共有ｒａｓ阻害剤及びその使用
|
|
AU2020403145B2
(en)
|
2019-12-13 |
2025-06-26 |
Genentech, Inc. |
Anti-Ly6G6D antibodies and methods of use
|
|
EP4076667A1
(en)
|
2019-12-20 |
2022-10-26 |
Erasca, Inc. |
Tricyclic pyridones and pyrimidones
|
|
AU2021206217A1
(en)
|
2020-01-07 |
2022-09-01 |
Revolution Medicines, Inc. |
SHP2 inhibitor dosing and methods of treating cancer
|
|
AU2021211871A1
(en)
|
2020-01-20 |
2022-09-08 |
Astrazeneca Ab |
Epidermal growth factor receptor tyrosine kinase inhibitors for the treatment of cancer
|
|
WO2022050954A1
(en)
|
2020-09-04 |
2022-03-10 |
Genentech, Inc. |
Dosing for treatment with anti-tigit and anti-pd-l1 antagonist antibodies
|
|
WO2021194481A1
(en)
|
2020-03-24 |
2021-09-30 |
Genentech, Inc. |
Dosing for treatment with anti-tigit and anti-pd-l1 antagonist antibodies
|
|
TW202142230A
(zh)
|
2020-01-27 |
2021-11-16 |
美商建南德克公司 |
用於以抗ｔｉｇｉｔ拮抗體抗體治療癌症之方法
|
|
WO2021177980A1
(en)
|
2020-03-06 |
2021-09-10 |
Genentech, Inc. |
Combination therapy for cancer comprising pd-1 axis binding antagonist and il6 antagonist
|
|
WO2021202959A1
(en)
|
2020-04-03 |
2021-10-07 |
Genentech, Inc. |
Therapeutic and diagnostic methods for cancer
|
|
CN115885050A
(zh)
|
2020-04-28 |
2023-03-31 |
基因泰克公司 |
用于非小细胞肺癌免疫疗法的方法和组合物
|
|
MX2022015877A
(es)
|
2020-06-16 |
2023-01-24 |
Genentech Inc |
Metodos y composiciones para tratar cancer de mama triple negativo.
|
|
CA3183032A1
(en)
|
2020-06-18 |
2021-12-23 |
Mallika Singh |
Methods for delaying, preventing, and treating acquired resistance to ras inhibitors
|
|
CN115916348A
(zh)
|
2020-06-18 |
2023-04-04 |
基因泰克公司 |
使用抗tigit抗体和pd-1轴结合拮抗剂的治疗
|
|
CN115843335A
(zh)
|
2020-06-30 |
2023-03-24 |
国家医疗保健研究所 |
用于预测患有实体癌的患者在术前辅助治疗和根治性手术后复发和/或死亡风险的方法
|
|
EP4172621A1
(en)
|
2020-06-30 |
2023-05-03 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for predicting the risk of recurrence and/or death of patients suffering from a solid cancer after preoperative adjuvant therapies
|
|
US11787775B2
(en)
|
2020-07-24 |
2023-10-17 |
Genentech, Inc. |
Therapeutic compounds and methods of use
|
|
JP2023536602A
(ja)
|
2020-08-03 |
2023-08-28 |
ジェネンテック， インコーポレイテッド |
リンパ腫のための診断及び治療方法
|
|
EP4196612A1
(en)
|
2020-08-12 |
2023-06-21 |
Genentech, Inc. |
Diagnostic and therapeutic methods for cancer
|
|
WO2022047243A1
(en)
|
2020-08-27 |
2022-03-03 |
Enosi Life Sciences Corp. |
Methods and compositions to treat autoimmune diseases and cancer
|
|
KR20230081726A
(ko)
|
2020-09-03 |
2023-06-07 |
레볼루션 메디슨즈, 인크. |
Shp2 돌연변이가 있는 악성 종양을 치료하기 위한 sos1 억제제의 용도
|
|
CA3194067A1
(en)
|
2020-09-15 |
2022-03-24 |
Revolution Medicines, Inc. |
Ras inhibitors
|
|
AU2021347232A1
(en)
|
2020-09-23 |
2023-04-27 |
Erasca, Inc. |
Tricyclic pyridones and pyrimidones
|
|
CN116406291A
(zh)
|
2020-10-05 |
2023-07-07 |
基因泰克公司 |
用抗fcrh5/抗cd3双特异性抗体进行治疗的给药
|
|
WO2022133345A1
(en)
|
2020-12-18 |
2022-06-23 |
Erasca, Inc. |
Tricyclic pyridones and pyrimidones
|
|
TW202241885A
(zh)
|
2020-12-22 |
2022-11-01 |
大陸商上海齊魯銳格醫藥研發有限公司 |
Ｓｏｓ１抑制劑及其用途
|
|
KR20230146052A
(ko)
|
2021-02-12 |
2023-10-18 |
에프. 호프만-라 로슈 아게 |
암 치료용 비시클릭 테트라히드로아제핀 유도체
|
|
EP4294804A1
(en)
|
2021-02-19 |
2023-12-27 |
Exelixis, Inc. |
Pyridone compounds and methods of use
|
|
AR125787A1
(es)
|
2021-05-05 |
2023-08-16 |
Revolution Medicines Inc |
Inhibidores de ras
|
|
PE20240088A1
(es)
|
2021-05-05 |
2024-01-16 |
Revolution Medicines Inc |
Inhibidores de ras
|
|
JP2024516450A
(ja)
|
2021-05-05 |
2024-04-15 |
レボリューション メディシンズ インコーポレイテッド |
共有結合性ｒａｓ阻害剤及びその使用
|
|
TW202313633A
(zh)
|
2021-05-25 |
2023-04-01 |
美商伊瑞斯卡公司 |
含硫雜芳族三環ｋｒａｓ抑制劑
|
|
US20240293558A1
(en)
|
2021-06-16 |
2024-09-05 |
Erasca, Inc. |
Kras inhibitor conjugates
|
|
WO2023001894A1
(en)
|
2021-07-20 |
2023-01-26 |
Ags Therapeutics Sas |
Extracellular vesicles from microalgae, their preparation, and uses
|
|
EP4384522A1
(en)
|
2021-08-10 |
2024-06-19 |
Erasca, Inc. |
Selective kras inhibitors
|
|
AR127308A1
(es)
|
2021-10-08 |
2024-01-10 |
Revolution Medicines Inc |
Inhibidores ras
|
|
WO2023097195A1
(en)
|
2021-11-24 |
2023-06-01 |
Genentech, Inc. |
Therapeutic indazole compounds and methods of use in the treatment of cancer
|
|
JP2024543912A
(ja)
|
2021-11-24 |
2024-11-26 |
ジェネンテック， インコーポレイテッド |
二環式治療用化合物及びがんの処置における使用方法
|
|
CN119212994A
(zh)
|
2021-12-17 |
2024-12-27 |
建新公司 |
作为shp2抑制剂的吡唑并吡嗪化合物
|
|
WO2023144127A1
(en)
|
2022-01-31 |
2023-08-03 |
Ags Therapeutics Sas |
Extracellular vesicles from microalgae, their biodistribution upon administration, and uses
|
|
EP4227307A1
(en)
|
2022-02-11 |
2023-08-16 |
Genzyme Corporation |
Pyrazolopyrazine compounds as shp2 inhibitors
|
|
CN119136806A
(zh)
|
2022-03-08 |
2024-12-13 |
锐新医药公司 |
用于治疗免疫难治性肺癌的方法
|
|
CN119278041A
(zh)
|
2022-03-31 |
2025-01-07 |
阿斯利康(瑞典)有限公司 |
用于治疗癌症的与akt抑制剂组合的表皮生长因子受体（egfr）酪氨酸激酶抑制剂
|
|
EP4504780A1
(en)
|
2022-04-01 |
2025-02-12 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
|
IL316738A
(en)
|
2022-05-11 |
2024-12-01 |
Genentech Inc |
Dosage for treatment with anti-FCRH5/anti-CD3 bispecific antibodies
|
|
IL317449A
(en)
|
2022-06-07 |
2025-02-01 |
Genentech Inc |
Method for determining the efficacy of a lung cancer treatment comprising an anti-PD-L1 antagonist and an anti-TIGIT antibody-antagonist
|
|
CN119998298A
(zh)
|
2022-06-10 |
2025-05-13 |
锐新医药公司 |
大环ras抑制剂
|
|
CN119421895A
(zh)
|
2022-06-27 |
2025-02-11 |
阿斯利康(瑞典)有限公司 |
涉及用于治疗癌症的表皮生长因子受体酪氨酸激酶抑制剂的组合
|
|
EP4554978A1
(en)
|
2022-07-13 |
2025-05-21 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
|
KR20250040020A
(ko)
|
2022-07-19 |
2025-03-21 |
제넨테크, 인크. |
항-fcrh5/항-cd3 이중특이성 항체로 치료하기 위한 투약법
|
|
IL318163A
(en)
|
2022-08-11 |
2025-03-01 |
Hoffmann La Roche |
TETRAHYDROTHIAZEPINE DERIVATIVES CYCLES
|
|
JP2025526683A
(ja)
|
2022-08-11 |
2025-08-15 |
エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト |
二環式テトラヒドロチアゼピン誘導体
|
|
EP4568959A1
(en)
|
2022-08-11 |
2025-06-18 |
F. Hoffmann-La Roche AG |
Bicyclic tetrahydrothiazepine derivatives
|
|
TW202417001A
(zh)
|
2022-08-11 |
2024-05-01 |
瑞士商赫孚孟拉羅股份公司 |
雙環四氫吖呯衍生物
|
|
EP4601644A1
(en)
|
2022-10-14 |
2025-08-20 |
Black Diamond Therapeutics, Inc. |
Methods of treating cancers using isoquinoline or 6-aza-quinoline derivatives
|
|
WO2024085242A2
(en)
|
2022-10-21 |
2024-04-25 |
Kawasaki Institute Of Industrial Promotion |
Non-fouling or super stealth vesicle
|
|
WO2024088808A1
(en)
|
2022-10-24 |
2024-05-02 |
Ags Therapeutics Sas |
Extracellular vesicles from microalgae, their biodistribution upon intranasal administration, and uses thereof
|
|
TW202426505A
(zh)
|
2022-10-25 |
2024-07-01 |
美商建南德克公司 |
癌症之治療及診斷方法
|
|
TW202434206A
(zh)
|
2023-02-17 |
2024-09-01 |
美商伊瑞斯卡公司 |
Ｋｒａｓ抑制劑
|
|
TW202504611A
(zh)
|
2023-03-30 |
2025-02-01 |
美商銳新醫藥公司 |
用於誘導ｒａｓ ｇｔｐ水解之組合物及其用途
|
|
WO2024211712A1
(en)
|
2023-04-07 |
2024-10-10 |
Revolution Medicines, Inc. |
Condensed macrocyclic compounds as ras inhibitors
|
|
WO2024211663A1
(en)
|
2023-04-07 |
2024-10-10 |
Revolution Medicines, Inc. |
Condensed macrocyclic compounds as ras inhibitors
|
|
US20240352038A1
(en)
|
2023-04-14 |
2024-10-24 |
Revolution Medicines, Inc. |
Crystalline forms of ras inhibitors, compositions containing the same, and methods of use thereof
|
|
US20240352036A1
(en)
|
2023-04-14 |
2024-10-24 |
Revolution Medicines, Inc. |
Crystalline forms of ras inhibitors, compositions containing the same, and methods of use thereof
|
|
WO2024229406A1
(en)
|
2023-05-04 |
2024-11-07 |
Revolution Medicines, Inc. |
Combination therapy for a ras related disease or disorder
|
|
WO2024233341A1
(en)
|
2023-05-05 |
2024-11-14 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
|
TW202504641A
(zh)
|
2023-06-08 |
2025-02-01 |
美商建南德克公司 |
用於淋巴瘤之診斷及治療方法的巨噬細胞特徵
|
|
WO2025024257A1
(en)
|
2023-07-21 |
2025-01-30 |
Genentech, Inc. |
Diagnostic and therapeutic methods for cancer
|
|
WO2025034702A1
(en)
|
2023-08-07 |
2025-02-13 |
Revolution Medicines, Inc. |
Rmc-6291 for use in the treatment of ras protein-related disease or disorder
|
|
TW202515614A
(zh)
|
2023-08-25 |
2025-04-16 |
美商建南德克公司 |
治療非小細胞肺癌之方法及組成物
|
|
WO2025080946A2
(en)
|
2023-10-12 |
2025-04-17 |
Revolution Medicines, Inc. |
Ras inhibitors
|
|
WO2025137507A1
(en)
|
2023-12-22 |
2025-06-26 |
Regor Pharmaceuticals, Inc. |
Sos1 inhibitors and uses thereof
|
|
WO2025171296A1
(en)
|
2024-02-09 |
2025-08-14 |
Revolution Medicines, Inc. |
Ras inhibitors
|
|
WO2025176847A1
(en)
|
2024-02-21 |
2025-08-28 |
Ags Therapeutics Sas |
Ocular delivery of active agents via microalgae extracellular vesicles
|