ATE240307T1 - Diarylalkenylamin-derivate - Google Patents

Diarylalkenylamin-derivate

Info

Publication number
ATE240307T1
ATE240307T1 AT96931791T AT96931791T ATE240307T1 AT E240307 T1 ATE240307 T1 AT E240307T1 AT 96931791 T AT96931791 T AT 96931791T AT 96931791 T AT96931791 T AT 96931791T AT E240307 T1 ATE240307 T1 AT E240307T1
Authority
AT
Austria
Prior art keywords
diarylalkenylamin
derivatives
diarylalkenylamin derivatives
Prior art date
Application number
AT96931791T
Other languages
English (en)
Inventor
Giulio Dondio
Silvano Ronzoni
Original Assignee
Glaxosmithkline Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Spa filed Critical Glaxosmithkline Spa
Application granted granted Critical
Publication of ATE240307T1 publication Critical patent/ATE240307T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182Radicals derived from carboxylic acids
    • C07D295/192Radicals derived from carboxylic acids from aromatic carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/28Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
    • C07C237/30Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to hydrogen atoms or to acyclic carbon atoms
AT96931791T 1995-09-15 1996-09-09 Diarylalkenylamin-derivate ATE240307T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT95MI001930A IT1277597B1 (it) 1995-09-15 1995-09-15 Derivati di diarilalchenilammina
PCT/EP1996/003988 WO1997010230A1 (en) 1995-09-15 1996-09-09 Diarylalkenylamine derivatives

Publications (1)

Publication Number Publication Date
ATE240307T1 true ATE240307T1 (de) 2003-05-15

Family

ID=11372254

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96931791T ATE240307T1 (de) 1995-09-15 1996-09-09 Diarylalkenylamin-derivate

Country Status (22)

Country Link
US (1) US6262104B1 (de)
EP (1) EP0873330B1 (de)
JP (1) JPH11512413A (de)
KR (1) KR19990044675A (de)
CN (1) CN1202164A (de)
AR (1) AR004205A1 (de)
AT (1) ATE240307T1 (de)
AU (1) AU706980B2 (de)
BR (1) BR9610597A (de)
CA (1) CA2232161A1 (de)
CZ (1) CZ78598A3 (de)
DE (1) DE69628200T2 (de)
ES (1) ES2195010T3 (de)
HU (1) HUP9900374A3 (de)
IL (1) IL123621A0 (de)
IT (1) IT1277597B1 (de)
NO (1) NO981131L (de)
NZ (1) NZ318774A (de)
PL (1) PL325552A1 (de)
TR (1) TR199800478T1 (de)
WO (1) WO1997010230A1 (de)
ZA (1) ZA967741B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5985880A (en) 1996-06-05 1999-11-16 Delta Pharmaceuticals Compositions and methods for reducing respiratory depression and attendant side effects of mu opioid compounds
US6103722A (en) * 1997-07-23 2000-08-15 The Medical College Of Wisconsin Research Foundation Inc. Ischemic preconditioning
DE69831876T2 (de) * 1997-12-24 2006-07-27 Ortho-Mcneil Pharmaceutical, Inc. (4)-[aryl(piperidin-4-yl) aminobenzamidderivate die an delta-opioid rezeptor binden
US6436959B1 (en) 1998-12-23 2002-08-20 Ortho-Mcneil Pharmaceutical, Inc. 4-[aryl(piperidin-4-yl)]aminobenzamides
ATE302184T1 (de) * 2000-02-18 2005-09-15 Meiji Seika Kaisha Phenoxyalkylaminderivate als agonisten des opioid-delta rezeptors
EP1277737A4 (de) * 2000-03-24 2003-05-07 Meiji Seika Kaisha DIPHENYLALKYLAMIN-DERIVATE ALS AGONISTEN DES OPIOID -g(d)-REZEPTORS
EP1680109A4 (de) * 2003-10-07 2009-05-06 Renovis Inc Amid-derivate als ionenkanal-liganden und pharmazeutische zusammensetzungen und anwendungsverfahren
WO2006023757A2 (en) * 2004-08-19 2006-03-02 University Of Virginia Patent Foundation Novel tricyclic, bicyclic, monocyclic, and acyclic amines as potent sodium channel blocking agents
US20080045610A1 (en) * 2004-09-23 2008-02-21 Alexander Michalow Methods for regulating neurotransmitter systems by inducing counteradaptations
EP1809104A4 (de) * 2004-09-23 2009-04-29 Alexander Michalow Verfahren zum regeln von neurotransmittersystemen durch gegenadaptationen
US7576099B2 (en) 2005-02-28 2009-08-18 Renovis, Inc. Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same
BRPI0606365A2 (pt) * 2005-02-28 2017-06-27 Renovis Inc composto ou um sal, solvato ou pró-droga farmaceuticamente aceitável do mesmo e estereoisômeros e tautômeros do mesmo, composição farmacêutica, métodos para prevenir, tratar, melhorar ou controlar uma doença ou condição e para preparar um composto, uso de um composto ou um sal, solvato ou composição farmaceuticamente aceitável do mesmo, método de tratamento de um mamífero, e, combinação

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0028682A3 (de) * 1977-07-04 1981-08-05 Astra Läkemedel Aktiebolag Bei der Herstellung von Verbindungen mit antidepressiver oder tranquillisierender Wirkung nützliche Zwischenprodukte
YU44821B (en) * 1982-02-04 1991-02-28 Wellcome Found Process for obtaiing new pyridyl derivatives
US4514414A (en) * 1982-10-25 1985-04-30 Smithkline Beckman Corporation N-Substituted pyrrolidineacetic acids and their esters
US4564685A (en) * 1983-03-10 1986-01-14 Findlay John W A Diphenylmethane compounds
ES2061432T3 (es) * 1985-10-09 1994-12-16 Shell Int Research Nuevas amidas de acido acrilico.
NZ234110A (en) 1989-06-19 1993-01-27 Wellcome Found Dibenzoazepine, -oxepine and -cycloheptane substituted alkylidene amines; pharmaceutical compositions containing such compounds or various other aryl substituted amines

Also Published As

Publication number Publication date
BR9610597A (pt) 1999-07-06
IT1277597B1 (it) 1997-11-11
DE69628200T2 (de) 2003-11-27
AR004205A1 (es) 1998-11-04
ITMI951930A1 (it) 1997-03-15
ZA967741B (en) 1998-03-13
CZ78598A3 (cs) 1998-08-12
AU706980B2 (en) 1999-07-01
DE69628200D1 (de) 2003-06-18
KR19990044675A (ko) 1999-06-25
TR199800478T1 (xx) 1998-06-22
AU7084796A (en) 1997-04-01
NO981131L (no) 1998-03-16
NZ318774A (en) 1998-08-26
US6262104B1 (en) 2001-07-17
ITMI951930A0 (it) 1995-09-15
ES2195010T3 (es) 2003-12-01
NO981131D0 (no) 1998-03-13
JPH11512413A (ja) 1999-10-26
EP0873330B1 (de) 2003-05-14
EP0873330A1 (de) 1998-10-28
WO1997010230A1 (en) 1997-03-20
MX9802024A (es) 1998-08-30
CN1202164A (zh) 1998-12-16
HUP9900374A3 (en) 1999-11-29
HUP9900374A2 (hu) 1999-06-28
IL123621A0 (en) 1998-10-30
CA2232161A1 (en) 1997-03-20
PL325552A1 (en) 1998-08-03

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties