ZA200100971B - Hepatitis C inhibitor tri-peptides - Google Patents
Hepatitis C inhibitor tri-peptides Download PDFInfo
- Publication number
- ZA200100971B ZA200100971B ZA200100971A ZA200100971A ZA200100971B ZA 200100971 B ZA200100971 B ZA 200100971B ZA 200100971 A ZA200100971 A ZA 200100971A ZA 200100971 A ZA200100971 A ZA 200100971A ZA 200100971 B ZA200100971 B ZA 200100971B
- Authority
- ZA
- South Africa
- Prior art keywords
- alkyl
- optionally substituted
- formula
- amido
- substituted
- Prior art date
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- 208000005176 Hepatitis C Diseases 0.000 title claims description 19
- 239000003112 inhibitor Substances 0.000 title claims description 14
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- 125000003118 aryl group Chemical group 0.000 claims description 111
- 125000003710 aryl alkyl group Chemical group 0.000 claims description 91
- 125000005843 halogen group Chemical group 0.000 claims description 74
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- 238000000034 method Methods 0.000 claims description 65
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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