UA122666C2 - Ізольоване антитiло або його антигензв'язувальний фрагмент, що специфічно зв'язується з людським білком програмованої смерті-1 (pd-1) - Google Patents

Ізольоване антитiло або його антигензв'язувальний фрагмент, що специфічно зв'язується з людським білком програмованої смерті-1 (pd-1) Download PDF

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Publication number
UA122666C2
UA122666C2 UAA201608946A UAA201608946A UA122666C2 UA 122666 C2 UA122666 C2 UA 122666C2 UA A201608946 A UAA201608946 A UA A201608946A UA A201608946 A UAA201608946 A UA A201608946A UA 122666 C2 UA122666 C2 UA 122666C2
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Ukraine
Prior art keywords
antibody
antigen
antibodies
binding
binding fragment
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UAA201608946A
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English (en)
Ukrainian (uk)
Inventor
Ніколас Дж. Пападопулос
Николас Дж. ПАПАДОПУЛОС
Ендрю Дж. Мерфі
Эндрю Дж. Мэрфи
Ґевін Терстон
Гэвин ТЕРСТОН
Елла Іоффе
Эла Иофе
Елена Бурова
Original Assignee
Ридженерон Фармасьютикалз, Інк.
Ридженерон Фармасьютикалз, Инк.
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=52462456&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA122666(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ридженерон Фармасьютикалз, Інк., Ридженерон Фармасьютикалз, Инк. filed Critical Ридженерон Фармасьютикалз, Інк.
Publication of UA122666C2 publication Critical patent/UA122666C2/uk

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    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
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    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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UAA201608946A 2014-01-23 2015-01-23 Ізольоване антитiло або його антигензв'язувальний фрагмент, що специфічно зв'язується з людським білком програмованої смерті-1 (pd-1) UA122666C2 (uk)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461930576P 2014-01-23 2014-01-23
US201462014181P 2014-06-19 2014-06-19
PCT/US2015/012589 WO2015112800A1 (en) 2014-01-23 2015-01-23 Human antibodies to pd-1

Publications (1)

Publication Number Publication Date
UA122666C2 true UA122666C2 (uk) 2020-12-28

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UAA201608946A UA122666C2 (uk) 2014-01-23 2015-01-23 Ізольоване антитiло або його антигензв'язувальний фрагмент, що специфічно зв'язується з людським білком програмованої смерті-1 (pd-1)

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US (4) US9987500B2 (enExample)
EP (2) EP3967710A1 (enExample)
JP (5) JP6425730B2 (enExample)
KR (2) KR20210152583A (enExample)
CN (2) CN113248614A (enExample)
AU (1) AU2015209233B2 (enExample)
BR (1) BR122022010183B1 (enExample)
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SG (1) SG11201605482SA (enExample)
SI (1) SI3097119T1 (enExample)
SM (1) SMT202100669T1 (enExample)
TW (1) TWI681969B (enExample)
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