|
ZA935111B
(en)
*
|
1992-07-17 |
1994-02-04 |
Smithkline Beecham Corp |
Rapamycin derivatives
|
|
ZA935110B
(en)
*
|
1992-07-17 |
1994-02-04 |
Smithkline Beecham Corp |
Rapamycin derivatives
|
|
USRE40596E1
(en)
*
|
1993-04-08 |
2008-12-02 |
Novartis Ag |
Rapamycin assay
|
|
GB9307491D0
(en)
*
|
1993-04-08 |
1993-06-02 |
Sandoz Ltd |
Organic compounds
|
|
ES2295093T3
(es)
|
1993-04-23 |
2008-04-16 |
Wyeth |
Conjugados y anticuerpos de rapamicina.
|
|
US7279561B1
(en)
*
|
1993-04-23 |
2007-10-09 |
Wyeth |
Anti-rapamycin monoclonal antibodies
|
|
USRE37421E1
(en)
|
1993-07-16 |
2001-10-23 |
Smithkline Beecham Corporation |
Rapamycin derivatives
|
|
ATE398448T1
(de)
*
|
1993-09-28 |
2008-07-15 |
Scherer Gmbh R P |
Herstellung von weichgelatinekapseln
|
|
CA2175215C
(en)
*
|
1993-11-19 |
2008-06-03 |
Yat Sun Or |
Semisynthetic analogs of rapamycin (macrolides) being immunomodulators
|
|
US5527907A
(en)
*
|
1993-11-19 |
1996-06-18 |
Abbott Laboratories |
Macrolide immunomodulators
|
|
SK78196A3
(en)
*
|
1993-12-17 |
1997-02-05 |
Sandoz Ag |
Rapamycin demethoxy-derivatives, preparation method thereof and pharmaceutical agent containing them
|
|
GB9405350D0
(en)
*
|
1994-03-18 |
1994-05-04 |
Sandoz Ltd |
Organic compounds
|
|
US7205279B2
(en)
*
|
1995-10-25 |
2007-04-17 |
Novartis Ag |
Pharmaceutical compositions
|
|
CN100335063C
(zh)
*
|
1994-10-26 |
2007-09-05 |
诺瓦蒂斯有限公司 |
药物组合物
|
|
IL129547A
(en)
|
1994-10-26 |
2001-01-11 |
Novartis Ag |
Pharmaceutical compositions comprising a macrolide and an acid
|
|
US5561138A
(en)
*
|
1994-12-13 |
1996-10-01 |
American Home Products Corporation |
Method of treating anemia
|
|
GB9618952D0
(en)
*
|
1996-09-11 |
1996-10-23 |
Sandoz Ltd |
Process
|
|
US6187757B1
(en)
|
1995-06-07 |
2001-02-13 |
Ariad Pharmaceuticals, Inc. |
Regulation of biological events using novel compounds
|
|
US5985890A
(en)
*
|
1995-06-09 |
1999-11-16 |
Novartis Ag |
Rapamycin derivatives
|
|
FR2736550B1
(fr)
|
1995-07-14 |
1998-07-24 |
Sandoz Sa |
Composition pharmaceutique sous la forme d'une dispersion solide comprenant un macrolide et un vehicule
|
|
US5780462A
(en)
*
|
1995-12-27 |
1998-07-14 |
American Home Products Corporation |
Water soluble rapamycin esters
|
|
GB9601120D0
(en)
*
|
1996-01-19 |
1996-03-20 |
Sandoz Ltd |
Organic compounds
|
|
GB9606452D0
(en)
*
|
1996-03-27 |
1996-06-05 |
Sandoz Ltd |
Organic compounds
|
|
KR100616020B1
(ko)
*
|
1996-03-27 |
2007-01-31 |
노파르티스 아게 |
맥관장애및이종이식술에서의라파마이신유도체의용도
|
|
PT956034E
(pt)
|
1996-07-30 |
2002-12-31 |
Novartis Ag |
Composicoes farmaceuticas para o tratamento da rejeicao de transplantes estados inflamatorios ou auto-imunes compreendendo ciclosporina a e 40-o-(2-hidroxietil)-rapamicina
|
|
EP0927182A2
(en)
*
|
1996-09-09 |
1999-07-07 |
American Home Products Corporation |
Alkylated rapamycin derivatives
|
|
US5922730A
(en)
*
|
1996-09-09 |
1999-07-13 |
American Home Products Corporation |
Alkylated rapamycin derivatives
|
|
GB9624038D0
(en)
*
|
1996-11-19 |
1997-01-08 |
Sandoz Ltd |
Organic compounds
|
|
US6220537B1
(en)
|
1997-03-07 |
2001-04-24 |
Daiwa Seiko, Inc. |
Fishing spinning reel having smoothly shaped rail portion
|
|
US6306166B1
(en)
*
|
1997-08-13 |
2001-10-23 |
Scimed Life Systems, Inc. |
Loading and release of water-insoluble drugs
|
|
PL342742A1
(en)
*
|
1998-03-06 |
2001-07-02 |
Novartis Ag |
Emulsion-type pre-concentrates containing cyclosporin or macrolyde
|
|
ME00189B
(me)
*
|
1998-03-26 |
2011-02-10 |
Astellas Pharma Inc |
Preparati sa neprekidnim oslobađanjem
|
|
US20050031611A1
(en)
*
|
1998-05-08 |
2005-02-10 |
Beth Israel Deaconess Medical Center |
Transplant tolerance by costimulation blockade and T-cell activation-induced apoptosis
|
|
PT1105395E
(pt)
*
|
1998-08-17 |
2002-09-30 |
Wyeth Corp |
Rapamicinas fotociclizadas
|
|
US6015809A
(en)
*
|
1998-08-17 |
2000-01-18 |
American Home Products Corporation |
Photocyclized rapamycin
|
|
GB9826882D0
(en)
*
|
1998-12-07 |
1999-01-27 |
Novartis Ag |
Organic compounds
|
|
US7276506B2
(en)
*
|
1998-12-28 |
2007-10-02 |
4 Aza Bioscience Nv |
Immunosuppressive effects of pteridine derivatives
|
|
US6946465B2
(en)
*
|
1999-02-02 |
2005-09-20 |
4 Aza Bioscience Nv |
Immunosuppressive effects of pteridine derivatives
|
|
US6318654B1
(en)
|
1999-03-07 |
2001-11-20 |
Daiwa Seiko, Inc. |
Spinning reel for fishing
|
|
US7063857B1
(en)
|
1999-04-30 |
2006-06-20 |
Sucampo Ag |
Use of macrolide compounds for the treatment of dry eye
|
|
DE60044717D1
(de)
|
1999-05-10 |
2010-09-02 |
Paolo Brenner |
Kombination von immunsuppressiven substanzen zur behandlung oder vorbeugung von transplantat abstossungen
|
|
USD440626S1
(en)
|
1999-06-08 |
2001-04-17 |
Daiwa Seiko, Inc. |
Line slider for a spinning fishing reel
|
|
US6331547B1
(en)
|
1999-08-18 |
2001-12-18 |
American Home Products Corporation |
Water soluble SDZ RAD esters
|
|
JP2003507382A
(ja)
*
|
1999-08-18 |
2003-02-25 |
ワイス |
水溶性ｓｄｚ−ｒａｄエステル
|
|
ATE264863T1
(de)
|
1999-08-24 |
2004-05-15 |
Ariad Gene Therapeutics Inc |
28-epirapaloge
|
|
US7067526B1
(en)
|
1999-08-24 |
2006-06-27 |
Ariad Gene Therapeutics, Inc. |
28-epirapalogs
|
|
US7807211B2
(en)
|
1999-09-03 |
2010-10-05 |
Advanced Cardiovascular Systems, Inc. |
Thermal treatment of an implantable medical device
|
|
US20070032853A1
(en)
*
|
2002-03-27 |
2007-02-08 |
Hossainy Syed F |
40-O-(2-hydroxy)ethyl-rapamycin coated stent
|
|
US6790228B2
(en)
|
1999-12-23 |
2004-09-14 |
Advanced Cardiovascular Systems, Inc. |
Coating for implantable devices and a method of forming the same
|
|
US6277983B1
(en)
|
2000-09-27 |
2001-08-21 |
American Home Products Corporation |
Regioselective synthesis of rapamycin derivatives
|
|
EP1250135B1
(en)
|
2000-01-14 |
2010-07-28 |
The Trustees of The University of Pennsylvania |
O-methylated rapamycin derivatives for alleviation and inhibition of lymphoproliferative disorders
|
|
GB0008785D0
(en)
|
2000-04-10 |
2000-05-31 |
Novartis Ag |
Organic compounds
|
|
US8236048B2
(en)
|
2000-05-12 |
2012-08-07 |
Cordis Corporation |
Drug/drug delivery systems for the prevention and treatment of vascular disease
|
|
US6670355B2
(en)
|
2000-06-16 |
2003-12-30 |
Wyeth |
Method of treating cardiovascular disease
|
|
JP2004507465A
(ja)
|
2000-08-11 |
2004-03-11 |
ワイス |
エストロゲン受容体陽性癌腫の治療方法
|
|
ATE411321T1
(de)
|
2000-09-19 |
2008-10-15 |
Wyeth Corp |
Wasserlösliche rapamycin-ester
|
|
US6399625B1
(en)
*
|
2000-09-27 |
2002-06-04 |
Wyeth |
1-oxorapamycins
|
|
CA2424029C
(en)
|
2000-09-29 |
2008-01-29 |
Cordis Corporation |
Coated medical devices
|
|
US6440991B1
(en)
*
|
2000-10-02 |
2002-08-27 |
Wyeth |
Ethers of 7-desmethlrapamycin
|
|
US6399626B1
(en)
|
2000-10-02 |
2002-06-04 |
Wyeth |
Hydroxyesters of 7-desmethylrapamycin
|
|
AU9598601A
(en)
|
2000-10-20 |
2002-04-29 |
Eisai Co Ltd |
Nitrogenous aromatic ring compounds
|
|
US7754208B2
(en)
|
2001-01-17 |
2010-07-13 |
Trubion Pharmaceuticals, Inc. |
Binding domain-immunoglobulin fusion proteins
|
|
AU2005201004A1
(en)
*
|
2001-02-19 |
2005-03-24 |
Novartis Ag |
Cancer treatment
|
|
MX368013B
(es)
|
2001-02-19 |
2019-09-13 |
Novartis Ag |
Tratamiento de cáncer.
|
|
AU2011226833B9
(en)
*
|
2001-02-19 |
2014-07-03 |
Novartis Ag |
Cancer treatment
|
|
AU2016206379B2
(en)
*
|
2001-02-19 |
2017-09-14 |
Novartis Ag |
Cancer Treatment
|
|
TWI233359B
(en)
*
|
2001-04-06 |
2005-06-01 |
Wyeth Corp |
Pharmaceutical composition for treating neoplasm
|
|
TWI296196B
(en)
*
|
2001-04-06 |
2008-05-01 |
Wyeth Corp |
Antineoplastic combinations
|
|
US6613083B2
(en)
|
2001-05-02 |
2003-09-02 |
Eckhard Alt |
Stent device and method
|
|
WO2003004098A1
(en)
|
2001-07-06 |
2003-01-16 |
Sucampo Ag |
Composition for topical administration comprising an interleukin-2 inhibitor and an antimicrobial agent
|
|
AU2002322720B2
(en)
|
2001-07-25 |
2008-11-13 |
Raptor Pharmaceutical Inc. |
Compositions and methods for modulating blood-brain barrier transport
|
|
US7682387B2
(en)
|
2002-04-24 |
2010-03-23 |
Biosensors International Group, Ltd. |
Drug-delivery endovascular stent and method for treating restenosis
|
|
US6939376B2
(en)
*
|
2001-11-05 |
2005-09-06 |
Sun Biomedical, Ltd. |
Drug-delivery endovascular stent and method for treating restenosis
|
|
US20050070468A1
(en)
*
|
2001-11-21 |
2005-03-31 |
Sucampo Ag |
Use of fk506 and analogues for treating allergic diseases
|
|
US20030176455A1
(en)
*
|
2002-03-13 |
2003-09-18 |
Wyeth |
Method of inhibiting cell death
|
|
US20040024450A1
(en)
*
|
2002-04-24 |
2004-02-05 |
Sun Biomedical, Ltd. |
Drug-delivery endovascular stent and method for treating restenosis
|
|
PT1505959E
(pt)
|
2002-05-16 |
2009-02-05 |
Novartis Ag |
Utilização de agentes de ligação do receptor edg em cancro
|
|
CA2492153C
(en)
|
2002-07-16 |
2012-05-08 |
Biotica Technology Limited |
Production of polyketide fkbp-ligand analogues
|
|
AR040693A1
(es)
|
2002-07-30 |
2005-04-13 |
Wyeth Corp |
Formulaciones parenterales
|
|
DK1539157T3
(da)
|
2002-09-18 |
2013-10-07 |
Univ Pennsylvania |
Fremgangsmåde til hæmning af choroidal neovaskularisering
|
|
EP1575576A2
(en)
|
2002-09-24 |
2005-09-21 |
Novartis AG |
Organic compounds
|
|
WO2004060283A2
(en)
|
2002-12-16 |
2004-07-22 |
Nitromed, Inc. |
Nitrosated and nitrosylated rapamycin compounds, compositions and methods of use
|
|
AU2003300076C1
(en)
|
2002-12-30 |
2010-03-04 |
Angiotech International Ag |
Drug delivery from rapid gelling polymer composition
|
|
AR042938A1
(es)
*
|
2003-02-06 |
2005-07-06 |
Wyeth Corp |
Uso del cci-779 en el tratamiento de la fibrosis hepatica
|
|
US20090093875A1
(en)
|
2007-05-01 |
2009-04-09 |
Abbott Laboratories |
Drug eluting stents with prolonged local elution profiles with high local concentrations and low systemic concentrations
|
|
AR043504A1
(es)
*
|
2003-03-17 |
2005-08-03 |
Novartis Ag |
Composiciones farmaceuticas que comprenden rapamicina para el tratamiento de enfermedades inflamatorias
|
|
GB0307867D0
(en)
*
|
2003-04-04 |
2003-05-14 |
Novartis Ag |
Pharmaceutical composition
|
|
US20070155771A1
(en)
*
|
2003-04-11 |
2007-07-05 |
David Rubinsztein |
Methods and means for treating protein conformational disorders
|
|
DE602004004520T2
(de)
*
|
2003-04-22 |
2007-11-08 |
Wyeth |
Antineoplastische zusammensetzungen
|
|
US7160867B2
(en)
|
2003-05-16 |
2007-01-09 |
Isotechnika, Inc. |
Rapamycin carbohydrate derivatives
|
|
US20050118344A1
(en)
|
2003-12-01 |
2005-06-02 |
Pacetti Stephen D. |
Temperature controlled crimping
|
|
US20060173033A1
(en)
*
|
2003-07-08 |
2006-08-03 |
Michaela Kneissel |
Use of rapamycin and rapamycin derivatives for the treatment of bone loss
|
|
DK1663244T3
(da)
*
|
2003-09-12 |
2007-12-03 |
4 Aza Ip Nv |
Pteridin-derivater til behandling af TNF-alpha-beslægtede sygdomme
|
|
KR20060085246A
(ko)
|
2003-09-18 |
2006-07-26 |
마커사이트, 인코포레이티드 |
경공막 전달
|
|
US20070032477A1
(en)
*
|
2003-10-17 |
2007-02-08 |
Waer Mark J A |
Pteridine derivatives useful for making pharmaceutical compositions
|
|
US7220755B2
(en)
*
|
2003-11-12 |
2007-05-22 |
Biosensors International Group, Ltd. |
42-O-alkoxyalkyl rapamycin derivatives and compositions comprising same
|
|
US9114198B2
(en)
|
2003-11-19 |
2015-08-25 |
Advanced Cardiovascular Systems, Inc. |
Biologically beneficial coatings for implantable devices containing fluorinated polymers and methods for fabricating the same
|
|
GB0327840D0
(en)
*
|
2003-12-01 |
2003-12-31 |
Novartis Ag |
Organic compounds
|
|
ATE418559T1
(de)
*
|
2004-03-01 |
2009-01-15 |
Terumo Corp |
Verfahren zur herstellung von o-alkylierten rapamycinderivaten
|
|
WO2005088307A1
(en)
|
2004-03-10 |
2005-09-22 |
Seradyn Inc. |
Immunoassays for everolimus
|
|
AR047988A1
(es)
*
|
2004-03-11 |
2006-03-15 |
Wyeth Corp |
Combinaciones antineoplásicas de cci-779 y rituximab
|
|
US8551512B2
(en)
*
|
2004-03-22 |
2013-10-08 |
Advanced Cardiovascular Systems, Inc. |
Polyethylene glycol/poly(butylene terephthalate) copolymer coated devices including EVEROLIMUS
|
|
US8778014B1
(en)
|
2004-03-31 |
2014-07-15 |
Advanced Cardiovascular Systems, Inc. |
Coatings for preventing balloon damage to polymer coated stents
|
|
PL1735321T3
(pl)
*
|
2004-04-14 |
2009-04-30 |
Wyeth Corp |
Proces wytwarzania 42-estrów rapamycyny i 32-estrów FK-506 z kwasem dikarboksylowym, prekursory koniugatów rapamycyny oraz przeciwciała
|
|
CN1946852A
(zh)
*
|
2004-04-27 |
2007-04-11 |
惠氏公司 |
利用雷帕霉素特异性甲基化酶标记雷帕霉素
|
|
WO2006115509A2
(en)
|
2004-06-24 |
2006-11-02 |
Novartis Vaccines And Diagnostics Inc. |
Small molecule immunopotentiators and assays for their detection
|
|
US8709469B2
(en)
|
2004-06-30 |
2014-04-29 |
Abbott Cardiovascular Systems Inc. |
Anti-proliferative and anti-inflammatory agent combination for treatment of vascular disorders with an implantable medical device
|
|
GB0417852D0
(en)
|
2004-08-11 |
2004-09-15 |
Biotica Tech Ltd |
Production of polyketides and other natural products
|
|
CA2578245C
(en)
|
2004-08-27 |
2013-10-29 |
Cardinal Health 529, Llc |
Solvent free amorphous rapamycin
|
|
ATE428421T1
(de)
|
2004-09-17 |
2009-05-15 |
Eisai R&D Man Co Ltd |
Medizinische zusammensetzung mit verbesserter stabilität und reduzierten gelierungseigenschaften
|
|
US7901451B2
(en)
|
2004-09-24 |
2011-03-08 |
Biosensors International Group, Ltd. |
Drug-delivery endovascular stent and method for treating restenosis
|
|
MX2007003789A
(es)
*
|
2004-10-04 |
2007-07-20 |
Qlt Usa Inc |
Suministro ocular de formulaciones polimericas para suministro.
|
|
US8313763B2
(en)
|
2004-10-04 |
2012-11-20 |
Tolmar Therapeutics, Inc. |
Sustained delivery formulations of rapamycin compounds
|
|
KR20070070184A
(ko)
*
|
2004-10-28 |
2007-07-03 |
와이어쓰 |
자궁근종의 치료에 있어서 ｍＴＯＲ 억제제의 용도
|
|
US8021849B2
(en)
|
2004-11-05 |
2011-09-20 |
Siemens Healthcare Diagnostics Inc. |
Methods and kits for the determination of sirolimus in a sample
|
|
WO2006053754A1
(en)
*
|
2004-11-19 |
2006-05-26 |
Novartis Ag |
COMBINATIONS OF ANTI-ATHEROSCLEROTIC PEPTIDES AND AN mTOR INHIBITING AGENT AND THEIR METHODS OF USE
|
|
WO2006071966A2
(en)
*
|
2004-12-29 |
2006-07-06 |
The Brigham And Women's Hospital, Inc. |
Rapamycin compounds in the treatment of neurofibromatosis type 1
|
|
DK1848431T3
(en)
|
2005-02-09 |
2016-04-18 |
Santen Pharmaceutical Co Ltd |
LIQUID FORMULATIONS FOR TREATMENT OF DISEASES OR CONDITIONS
|
|
US8663639B2
(en)
|
2005-02-09 |
2014-03-04 |
Santen Pharmaceutical Co., Ltd. |
Formulations for treating ocular diseases and conditions
|
|
GB0503936D0
(en)
*
|
2005-02-25 |
2005-04-06 |
San Raffaele Centro Fond |
Method
|
|
GB0504544D0
(en)
|
2005-03-04 |
2005-04-13 |
Novartis Ag |
Organic compounds
|
|
CA2602010A1
(en)
|
2005-03-07 |
2006-09-14 |
Wyeth |
Oxepane isomer of 42-o-(2-hydroxy)ethyl-rapamycin
|
|
WO2006095173A2
(en)
|
2005-03-11 |
2006-09-14 |
Biotica Technology Limited |
Medical uses of 39-desmethoxyrapamycin and analogues thereof
|
|
US20100061994A1
(en)
*
|
2005-03-11 |
2010-03-11 |
Rose Mary Sheridan |
Medical uses of 39-desmethoxyrapamycin and analogues thereof
|
|
GT200600148A
(es)
*
|
2005-04-14 |
2006-11-22 |
|
Metodos para el tratamiento y la prevencion de fibrosis
|
|
US7189582B2
(en)
|
2005-04-27 |
2007-03-13 |
Dade Behring Inc. |
Compositions and methods for detection of sirolimus
|
|
CA2789262C
(en)
|
2005-04-28 |
2016-10-04 |
Proteus Digital Health, Inc. |
Pharma-informatics system
|
|
BRPI0611021A2
(pt)
*
|
2005-05-31 |
2010-08-10 |
Novartis Ag |
combinação de inibidores de hmg-coa redutase e inibidores de mtor
|
|
US20070004767A1
(en)
*
|
2005-06-30 |
2007-01-04 |
Gutmann David H |
Methods for treating neurofibromatosis 1
|
|
WO2007011707A2
(en)
|
2005-07-15 |
2007-01-25 |
Micell Technologies, Inc. |
Polymer coatings containing drug powder of controlled morphology
|
|
WO2007011708A2
(en)
|
2005-07-15 |
2007-01-25 |
Micell Technologies, Inc. |
Stent with polymer coating containing amorphous rapamycin
|
|
JP2009501765A
(ja)
|
2005-07-20 |
2009-01-22 |
ノバルティス アクチエンゲゼルシャフト |
ピリミジルアミノベンズアミドとｍＴＯＲキナーゼ阻害剤の組み合わせ
|
|
RU2423381C2
(ru)
|
2005-07-25 |
2011-07-10 |
Трабьон Фармасьютикалз, Инк. |
Снижение количества в-клеток с использованием cd37-специфических и cd20-специфических связывающих молекул
|
|
JP4989476B2
(ja)
|
2005-08-02 |
2012-08-01 |
エーザイ・アール・アンド・ディー・マネジメント株式会社 |
血管新生阻害物質の効果を検定する方法
|
|
AU2006284922B2
(en)
|
2005-08-30 |
2012-01-19 |
University Of Miami |
Immunomodulating tumor necrosis factor receptor 25 (TNFR25) agonists, antagonists and immunotoxins
|
|
EP1776970A1
(en)
|
2005-10-12 |
2007-04-25 |
Albert Schömig |
Implant with multiple coating
|
|
EP1942937A1
(en)
|
2005-11-04 |
2008-07-16 |
Wyeth |
Antineoplastic combinations with mtor inhibitor, herceptin, and/or hki-272
|
|
GB0523659D0
(en)
*
|
2005-11-21 |
2005-12-28 |
Novartis Ag |
Organic compounds
|
|
US20070142422A1
(en)
*
|
2005-12-20 |
2007-06-21 |
Wyeth |
Control of CCI-779 dosage form stability through control of drug substance impurities
|
|
WO2007080124A1
(en)
*
|
2006-01-12 |
2007-07-19 |
Novartis Ag |
Combination of mtor inhibitor and antipolate compound
|
|
US20070173923A1
(en)
*
|
2006-01-20 |
2007-07-26 |
Savage Douglas R |
Drug reservoir stent
|
|
KR20080090493A
(ko)
|
2006-02-02 |
2008-10-08 |
노파르티스 아게 |
결절성 경화증의 치료
|
|
KR20140093764A
(ko)
|
2006-02-09 |
2014-07-28 |
산텐 세이야꾸 가부시키가이샤 |
안정한 제제와 그 제조 및 사용 방법
|
|
US7678901B2
(en)
|
2006-02-28 |
2010-03-16 |
Wyeth |
Rapamycin analogs containing an antioxidant moiety
|
|
US7622477B2
(en)
*
|
2006-02-28 |
2009-11-24 |
Cordis Corporation |
Isomers and 42-epimers of rapamycin alkyl ether analogs, methods of making and using the same
|
|
CN101394867A
(zh)
*
|
2006-03-07 |
2009-03-25 |
惠氏公司 |
大环内酯类免疫抑制剂的水溶性聚乙二醇结合物的制备方法
|
|
ES2563288T3
(es)
|
2006-03-23 |
2016-03-14 |
Santen Pharmaceutical Co., Ltd |
Rapamicina en dosis bajas para el tratamiento de enfermedades relacionadas con la permeabilidad vascular
|
|
ES2540059T3
(es)
|
2006-04-26 |
2015-07-08 |
Micell Technologies, Inc. |
Recubrimientos que contienen múltiples fármacos
|
|
CN104706637A
(zh)
|
2006-05-18 |
2015-06-17 |
卫材R&D管理有限公司 |
针对甲状腺癌的抗肿瘤剂
|
|
GB0609962D0
(en)
*
|
2006-05-19 |
2006-06-28 |
Biotica Tech Ltd |
Novel compounds
|
|
GB0609963D0
(en)
*
|
2006-05-19 |
2006-06-28 |
Biotica Tech Ltd |
Novel compounds
|
|
WO2008053362A2
(en)
*
|
2006-06-30 |
2008-05-08 |
Interface Biologics, Inc. |
Bioresponsive polymers
|
|
WO2008009078A2
(en)
|
2006-07-20 |
2008-01-24 |
Gilead Sciences, Inc. |
4,6-dl- and 2,4,6-trisubstituted quinazoline derivatives useful for treating viral infections
|
|
US10144736B2
(en)
*
|
2006-07-20 |
2018-12-04 |
Gilead Sciences, Inc. |
Substituted pteridines useful for the treatment and prevention of viral infections
|
|
US20100266590A1
(en)
*
|
2006-08-02 |
2010-10-21 |
Demetri George D |
Combination therapy
|
|
WO2008026748A1
(en)
|
2006-08-28 |
2008-03-06 |
Eisai R & D Management Co., Ltd. |
Antitumor agent for undifferentiated gastric cancer
|
|
US20080051691A1
(en)
*
|
2006-08-28 |
2008-02-28 |
Wyeth |
Implantable shunt or catheter enabling gradual delivery of therapeutic agents
|
|
US8088789B2
(en)
|
2006-09-13 |
2012-01-03 |
Elixir Medical Corporation |
Macrocyclic lactone compounds and methods for their use
|
|
EP2083834B1
(en)
|
2006-09-13 |
2017-06-21 |
Elixir Medical Corporation |
Macrocyclic lactone compounds and methods for their use
|
|
US10695327B2
(en)
|
2006-09-13 |
2020-06-30 |
Elixir Medical Corporation |
Macrocyclic lactone compounds and methods for their use
|
|
EP2063905B1
(en)
|
2006-09-18 |
2014-07-30 |
Raptor Pharmaceutical Inc |
Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates
|
|
US8067055B2
(en)
*
|
2006-10-20 |
2011-11-29 |
Biosensors International Group, Ltd. |
Drug-delivery endovascular stent and method of use
|
|
US20080097591A1
(en)
|
2006-10-20 |
2008-04-24 |
Biosensors International Group |
Drug-delivery endovascular stent and method of use
|
|
EP2090580B1
(en)
|
2006-11-27 |
2014-06-04 |
Terumo Kabushiki Kaisha |
Process for producing o-alkylated rapamycin derivative, and o-alkylated rapamycin derivative
|
|
CA2679712C
(en)
|
2007-01-08 |
2016-11-15 |
Micell Technologies, Inc. |
Stents having biodegradable layers
|
|
US11426494B2
(en)
|
2007-01-08 |
2022-08-30 |
MT Acquisition Holdings LLC |
Stents having biodegradable layers
|
|
ES2393639T3
(es)
|
2007-01-21 |
2012-12-26 |
Hemoteq Ag |
Producto médico para tratar cierres de conductos corporales y prevención de nuevos cierres
|
|
CA2676796C
(en)
|
2007-01-29 |
2016-02-23 |
Eisai R & D Management Co., Ltd. |
Composition for treatment of undifferentiated gastric cancer
|
|
TW200845960A
(en)
*
|
2007-04-05 |
2008-12-01 |
Wyeth Corp |
Wortmannin-rapalog conjugate and uses thereof
|
|
TW200901989A
(en)
|
2007-04-10 |
2009-01-16 |
Wyeth Corp |
Anti-tumor activity of CCI-779 in papillary renal cell cancer
|
|
US9192697B2
(en)
|
2007-07-03 |
2015-11-24 |
Hemoteq Ag |
Balloon catheter for treating stenosis of body passages and for preventing threatening restenosis
|
|
JP5599712B2
(ja)
|
2007-10-05 |
2014-10-01 |
インターフェース バイオロジクス，インコーポレーテッド |
オリゴフッ素化架橋ポリマーおよびそれの使用
|
|
CA2703017C
(en)
|
2007-10-19 |
2017-04-25 |
Roseita Esfand |
Self-eliminating coatings
|
|
US8952035B2
(en)
|
2007-11-09 |
2015-02-10 |
Eisai R&D Management Co., Ltd. |
Combination of anti-angiogenic substance and anti-tumor platinum complex
|
|
EP2219700B1
(en)
|
2007-11-14 |
2024-03-20 |
Biosensors International Group, Ltd. |
Automated coating apparatus and method
|
|
US8921642B2
(en)
|
2008-01-11 |
2014-12-30 |
Massachusetts Eye And Ear Infirmary |
Conditional-stop dimerizable caspase transgenic animals
|
|
WO2009114010A1
(en)
*
|
2008-03-11 |
2009-09-17 |
Elixir Medical Corporation |
Macrocyclic lactone compounds and methods for their use
|
|
US20100048913A1
(en)
|
2008-03-14 |
2010-02-25 |
Angela Brodie |
Novel C-17-Heteroaryl Steroidal CYP17 Inhibitors/Antiandrogens;Synthesis In Vitro Biological Activities, Pharmacokinetics and Antitumor Activity
|
|
CA2719134C
(en)
|
2008-03-21 |
2015-06-30 |
The University Of Chicago |
Treatment with opioid antagonists and mtor inhibitors
|
|
RU2531754C2
(ru)
|
2008-04-11 |
2014-10-27 |
ЭМЕРДЖЕНТ ПРОДАКТ ДИВЕЛОПМЕНТ СИЭТЛ,ЭлЭлСи,US |
Связывающееся с cd37 иммунотерапевтическое средство и его комбинация с бифункциональным химиотерапевтическим средством
|
|
US20110098241A1
(en)
*
|
2008-04-14 |
2011-04-28 |
Poniard Pharmaceuticals, Inc. |
Rapamycin analogs as anti-cancer agents
|
|
CN102083397B
(zh)
|
2008-04-17 |
2013-12-25 |
米歇尔技术公司 |
具有生物可吸收层的支架
|
|
JP2011525189A
(ja)
|
2008-06-20 |
2011-09-15 |
ノバルティス アーゲー |
多発性硬化症を治療するための小児科の組成物
|
|
US8765162B2
(en)
|
2008-06-30 |
2014-07-01 |
Abbott Cardiovascular Systems Inc. |
Poly(amide) and poly(ester-amide) polymers and drug delivery particles and coatings containing same
|
|
JP2011528275A
(ja)
|
2008-07-17 |
2011-11-17 |
ミセル テクノロジーズ，インク． |
薬物送達医療デバイス
|
|
US8092822B2
(en)
|
2008-09-29 |
2012-01-10 |
Abbott Cardiovascular Systems Inc. |
Coatings including dexamethasone derivatives and analogs and olimus drugs
|
|
US20100086579A1
(en)
*
|
2008-10-03 |
2010-04-08 |
Elixir Medical Corporation |
Macrocyclic lactone compounds and methods for their use
|
|
KR20110071014A
(ko)
|
2008-10-17 |
2011-06-27 |
위스콘신 얼럼나이 리서어치 화운데이션 |
생물학적으로 활성인 알파-베타 펩티드의 제조 방법
|
|
ES2645692T3
(es)
|
2008-11-11 |
2017-12-07 |
The Board Of Regents,The University Of Texas System |
Microcápsulas de rapamicina y su uso para el tratamiento del cáncer
|
|
AU2009329872B2
(en)
|
2008-12-23 |
2016-07-07 |
Gilead Pharmasset Llc |
Synthesis of purine nucleosides
|
|
NZ593649A
(en)
|
2008-12-23 |
2013-11-29 |
Gilead Pharmasset Llc |
Nucleoside analogs
|
|
PA8855601A1
(es)
|
2008-12-23 |
2010-07-27 |
|
Forformidatos de nucleósidos
|
|
CN102282457A
(zh)
*
|
2009-01-21 |
2011-12-14 |
拜康有限公司 |
确定西罗莫司稳定性的方法和制备其稳定形式的工艺
|
|
CN102686600A
(zh)
|
2009-02-05 |
2012-09-19 |
托凯药业股份有限公司 |
甾体cyp17抑制剂/抗雄激素物质的新型药物前体
|
|
WO2010103130A2
(en)
|
2009-03-13 |
2010-09-16 |
Katholieke Universiteit Leuven, K.U.Leuven R&D |
Novel bicyclic heterocycles
|
|
WO2010120552A2
(en)
|
2009-04-01 |
2010-10-21 |
Micell Technologies, Inc. |
Coated stents
|
|
WO2010120599A2
(en)
|
2009-04-16 |
2010-10-21 |
Merck Sharp & Dohme Corp. |
Compositions and methods for treating cancer
|
|
EP3366326A1
(en)
|
2009-04-17 |
2018-08-29 |
Micell Technologies, Inc. |
Stents having controlled elution
|
|
KR101909711B1
(ko)
|
2009-05-06 |
2018-12-19 |
라보라토리 스킨 케어, 인크. |
활성제-칼슘 포스페이트 입자 복합체를 포함하는 피부 전달 조성물 및 이들을 이용하는 방법
|
|
EP2944332B1
(en)
|
2009-07-10 |
2016-08-17 |
Boston Scientific Scimed, Inc. |
Use of nanocrystals for a drug delivery balloon
|
|
EP2453834A4
(en)
|
2009-07-16 |
2014-04-16 |
Micell Technologies Inc |
MEDICAL DEVICE DISPENSING MEDICINE
|
|
EP2453938B1
(en)
|
2009-07-17 |
2015-08-19 |
Boston Scientific Scimed, Inc. |
Nucleation of drug delivery balloons to provide improved crystal size and density
|
|
SG10201502330TA
(en)
|
2009-08-03 |
2015-05-28 |
Univ Miami |
Method for in vivo expansion of t regulatory cells
|
|
MY162940A
(en)
|
2009-08-19 |
2017-07-31 |
Eisai R&D Man Co Ltd |
Quinoline derivative-containing pharmaceutical composition
|
|
EA020151B1
(ru)
|
2009-10-23 |
2014-09-30 |
Эли Лилли Энд Компани |
Ингибиторы akt и фармацевтические составы, их содержащие
|
|
JP2013509444A
(ja)
|
2009-10-30 |
2013-03-14 |
アリアド・ファーマシューティカルズ・インコーポレイテッド |
がんの治療方法及び治療用組成物
|
|
US9283211B1
(en)
|
2009-11-11 |
2016-03-15 |
Rapamycin Holdings, Llc |
Oral rapamycin preparation and use for stomatitis
|
|
WO2015161139A1
(en)
|
2014-04-16 |
2015-10-22 |
Rapamycin Holdings, Llc |
Oral rapamycin preparation and use for stomatitis
|
|
KR20120107962A
(ko)
|
2009-11-18 |
2012-10-04 |
노파르티스 아게 |
고형 종양 및 다른 악성종양의 치료를 위한 방법 및 조성물
|
|
CN102933658A
(zh)
|
2009-12-18 |
2013-02-13 |
界面生物公司 |
从自组装涂层局部递送药物
|
|
CN102127092B
(zh)
*
|
2010-01-18 |
2013-04-17 |
东南大学 |
依维莫斯的制备
|
|
EP2531140B1
(en)
|
2010-02-02 |
2017-11-01 |
Micell Technologies, Inc. |
Stent and stent delivery system with improved deliverability
|
|
EP2542670A2
(en)
|
2010-03-05 |
2013-01-09 |
President and Fellows of Harvard College |
Induced dendritic cell compositions and uses thereof
|
|
SG184324A1
(en)
|
2010-03-31 |
2012-11-29 |
Gilead Pharmasset Llc |
Nucleoside phosphoramidates
|
|
EP2558092B1
(en)
|
2010-04-13 |
2018-06-27 |
Novartis AG |
Combination comprising a cyclin dependent kinase 4 or cyclin dependent kinase 6 (cdk4/6) inhibitor and an mtor inhibitor for treating cancer
|
|
CN102834094B
(zh)
|
2010-04-16 |
2015-05-06 |
诺华有限公司 |
有机化合物的组合产品及其制药用途
|
|
EP2560576B1
(en)
|
2010-04-22 |
2018-07-18 |
Micell Technologies, Inc. |
Stents and other devices having extracellular matrix coating
|
|
RU2585489C2
(ru)
|
2010-04-27 |
2016-05-27 |
Рош Гликарт Аг |
КОМБИНИРОВАННАЯ ТЕРАПИЯ АФУКОЗИЛИРОВАННЫМ АНТИТЕЛОМ CD20 И ИНГИБИТОРОМ mTOR
|
|
GB201012889D0
(en)
|
2010-08-02 |
2010-09-15 |
Univ Leuven Kath |
Antiviral activity of novel bicyclic heterocycles
|
|
CN102958523B
(zh)
|
2010-06-25 |
2014-11-19 |
卫材R&D管理有限公司 |
使用具有激酶抑制作用的组合的抗肿瘤剂
|
|
WO2012009684A2
(en)
|
2010-07-16 |
2012-01-19 |
Micell Technologies, Inc. |
Drug delivery medical device
|
|
EP2611476B1
(en)
|
2010-09-02 |
2016-08-10 |
Boston Scientific Scimed, Inc. |
Coating process for drug delivery balloons using heat-induced rewrap memory
|
|
GB201015411D0
(en)
|
2010-09-15 |
2010-10-27 |
Univ Leuven Kath |
Anti-cancer activity of novel bicyclic heterocycles
|
|
US20120077778A1
(en)
|
2010-09-29 |
2012-03-29 |
Andrea Bourdelais |
Ladder-Frame Polyether Conjugates
|
|
CN102464669B
(zh)
*
|
2010-11-17 |
2014-04-16 |
浙江海正药业股份有限公司 |
无定形依维莫司及其制备方法
|
|
ES2753529T3
(es)
|
2010-11-19 |
2020-04-13 |
Biocon Ltd |
Procesos para la preparación de everolimús y productos intermedios del mismo
|
|
EP2670758B1
(en)
|
2011-02-04 |
2022-09-28 |
Synthon BV |
Process for making trisubstituted silyloxyethyl triflates
|
|
ES2547916T3
(es)
|
2011-02-18 |
2015-10-09 |
Novartis Pharma Ag |
Terapia de combinación de inhibidores de mTOR/JAK
|
|
CN102174053B
(zh)
*
|
2011-03-09 |
2014-04-16 |
成都雅途生物技术有限公司 |
依维莫司的纯化方法
|
|
TR201909840T4
(tr)
|
2011-03-11 |
2019-07-22 |
Beth Israel Deaconess Medical Ct Inc |
Anti-CD40 antikorları ve kullanımları.
|
|
EP2508525A1
(en)
|
2011-04-05 |
2012-10-10 |
Bayer Pharma Aktiengesellschaft |
Substituted 2,3-dihydroimidazo[1,2-c]quinazoline salts
|
|
CN103402519B
(zh)
|
2011-04-18 |
2015-11-25 |
卫材R&D管理有限公司 |
肿瘤治疗剂
|
|
BR112013027486A2
(pt)
|
2011-04-25 |
2017-02-14 |
Novartis Ag |
combinação de um inibidor de fosfatidilinositol-3-cinase (pi3k) e um inibidor de mtor
|
|
WO2012149014A1
(en)
|
2011-04-25 |
2012-11-01 |
OSI Pharmaceuticals, LLC |
Use of emt gene signatures in cancer drug discovery, diagnostics, and treatment
|
|
JP6038128B2
(ja)
|
2011-06-03 |
2016-12-07 |
エーザイ・アール・アンド・ディー・マネジメント株式会社 |
レンバチニブ化合物に対する甲状腺癌対象及び腎臓癌対象の反応性を予測及び評価するためのバイオマーカー
|
|
JP2014516075A
(ja)
|
2011-06-06 |
2014-07-07 |
シェブロン フィリップス ケミカル カンパニー エルピー |
癌治療のためのメタロセン化合物の使用
|
|
EP2532740A1
(en)
|
2011-06-11 |
2012-12-12 |
Michael Schmück |
Antigen-specific CD4+ and CD8+ central-memory T cell preparations for adoptive T cell therapy
|
|
CA2841360A1
(en)
|
2011-07-15 |
2013-01-24 |
Micell Technologies, Inc. |
Drug delivery medical device
|
|
WO2013013708A1
(en)
|
2011-07-26 |
2013-01-31 |
Fundació Institut D'investigació Biomèdica De Bellvitge |
Treatment of acute rejection in renal transplant
|
|
US20130028895A1
(en)
|
2011-07-27 |
2013-01-31 |
Gerald Wulf |
Exosome inhibiting agents and uses thereof
|
|
US8669360B2
(en)
|
2011-08-05 |
2014-03-11 |
Boston Scientific Scimed, Inc. |
Methods of converting amorphous drug substance into crystalline form
|
|
WO2013028208A1
(en)
|
2011-08-25 |
2013-02-28 |
Boston Scientific Scimed, Inc. |
Medical device with crystalline drug coating
|
|
CN102268015B
(zh)
*
|
2011-08-30 |
2013-08-28 |
成都摩尔生物医药有限公司 |
一种依维莫司的合成方法
|
|
GB201115665D0
(en)
|
2011-09-09 |
2011-10-26 |
Univ Leuven Kath |
Autoimmune and inflammatory disorder therapy
|
|
ES2663744T3
(es)
|
2011-10-06 |
2018-04-16 |
Novartis Ag |
Composiciones farmacéuticas que comprenden 40-O-(2-hidroxi)etil-rapamicina
|
|
US10188772B2
(en)
|
2011-10-18 |
2019-01-29 |
Micell Technologies, Inc. |
Drug delivery medical device
|
|
EP2589383A1
(en)
|
2011-11-06 |
2013-05-08 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Berlin |
FKBP subtype-specific rapamycin analogue for use in treatment of diseases
|
|
GB201122305D0
(en)
|
2011-12-23 |
2012-02-01 |
Biotica Tech Ltd |
Novel compound
|
|
KR20160027219A
(ko)
|
2012-05-23 |
2016-03-09 |
에프. 호프만-라 로슈 아게 |
내배엽 및 간세포를 수득하고 사용하는 조성물 및 방법
|
|
CN102786534A
(zh)
*
|
2012-05-25 |
2012-11-21 |
上海现代制药股份有限公司 |
一种依维莫司的制备方法
|
|
ES2574522T3
(es)
|
2012-06-08 |
2016-06-20 |
Biotronik Ag |
Ésteres 40-O-hidrocarburo cíclico de rapamicina, composiciones y procedimientos
|
|
WO2013192367A1
(en)
|
2012-06-22 |
2013-12-27 |
Novartis Ag |
Neuroendocrine tumor treatment
|
|
CN103705925B
(zh)
|
2012-09-29 |
2018-03-30 |
段磊 |
抑制PI3K/AKT/mTOR信号通路的药物组合
|
|
US9750728B2
(en)
|
2012-09-29 |
2017-09-05 |
Targeted Therapeutics, Llc |
Method and pharmaceutical composition for inhibiting PI3K/AKT/mTOR signaling pathway
|
|
WO2014059295A1
(en)
|
2012-10-12 |
2014-04-17 |
The Board Of Regents Of The University Of Texas System |
Use of mtor inhibitors to treat vascular cognitive impairment
|
|
US20150258127A1
(en)
|
2012-10-31 |
2015-09-17 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for preventing antiphospholipid syndrome (aps)
|
|
US9757432B2
(en)
|
2012-11-14 |
2017-09-12 |
Ohio State Innovation Foundation |
Materials and methods useful for treating glioblastorna
|
|
SG11201404432QA
(en)
*
|
2012-11-30 |
2014-10-30 |
Hangzhou Zylox Pharma Co Ltd |
Rafamycin analogs and methods for making same
|
|
KR20150098605A
(ko)
|
2012-12-21 |
2015-08-28 |
에자이 알앤드디 매니지먼트 가부시키가이샤 |
퀴놀린 유도체의 비정질 형태 및 그의 제조방법
|
|
US20140193410A1
(en)
|
2013-01-09 |
2014-07-10 |
University Of Miami |
Compositions and Methods for the Regulation of T Regulatory Cells Using TL1A-Ig Fusion Protein
|
|
KR20150143476A
(ko)
|
2013-03-12 |
2015-12-23 |
미셀 테크놀로지즈, 인코포레이티드 |
생흡수성 생체의학적 임플란트
|
|
WO2014160328A1
(en)
|
2013-03-13 |
2014-10-02 |
The Board Of Regents Of The University Of Texas System |
Mtor inhibitors for prevention of intestinal polyp growth
|
|
RU2015137617A
(ru)
|
2013-03-14 |
2017-04-18 |
Юниверсити Оф Мэриленд, Балтимор Офис Оф Текнолоджи Трансфер |
Агенты, подавляющие андрогенные рецепторы, и их применение
|
|
US10098871B2
(en)
*
|
2013-03-15 |
2018-10-16 |
Leslie B. Gordon |
Combination therapies for treatment of laminopathies, cellular aging, and atherosclerosis
|
|
TW201503912A
(zh)
|
2013-03-19 |
2015-02-01 |
Novartis Ag |
包含癌莫事（ｅｖｅｒｏｌｉｍｕｓ）之醫藥組合物
|
|
EP2994758B1
(en)
|
2013-05-08 |
2017-12-20 |
Opthea Limited |
Biomarkers for age-related macular degeneration (amd)
|
|
NZ714049A
(en)
|
2013-05-14 |
2020-05-29 |
Eisai R&D Man Co Ltd |
Biomarkers for predicting and assessing responsiveness of endometrial cancer subjects to lenvatinib compounds
|
|
HK1222313A1
(zh)
|
2013-05-15 |
2017-06-30 |
Micell Technologies, Inc. |
可生物吸收的生物医学植入物
|
|
EP3008192B1
(en)
|
2013-06-11 |
2019-07-17 |
Takara Bio USA, Inc. |
Protein enriched microvesicles and methods of making and using the same
|
|
WO2014203185A1
(en)
*
|
2013-06-20 |
2014-12-24 |
Novartis Ag |
Alkylation with an alkyl fluoroalkyl sulfonate
|
|
CN103360411B
(zh)
*
|
2013-07-17 |
2015-09-30 |
成都雅途生物技术有限公司 |
依维莫司结晶提纯方法
|
|
CN105636594A
(zh)
|
2013-08-12 |
2016-06-01 |
托凯药业股份有限公司 |
使用雄激素靶向疗法用于治疗肿瘤性疾病的生物标记物
|
|
US9580758B2
(en)
|
2013-11-12 |
2017-02-28 |
Luc Montagnier |
System and method for the detection and treatment of infection by a microbial agent associated with HIV infection
|
|
AU2014348657A1
(en)
|
2013-11-13 |
2016-05-19 |
Novartis Ag |
mTOR inhibitors for enhancing the immune response
|
|
ES2918501T3
(es)
|
2013-12-19 |
2022-07-18 |
Novartis Ag |
Receptores de antígenos quiméricos de mesotelina humana y usos de los mismos
|
|
EP3087101B1
(en)
|
2013-12-20 |
2024-06-05 |
Novartis AG |
Regulatable chimeric antigen receptor
|
|
KR101529963B1
(ko)
*
|
2013-12-27 |
2015-06-19 |
주식회사 종근당바이오 |
에베로리무스의 제조방법 및 이의 중간체
|
|
US9700544B2
(en)
|
2013-12-31 |
2017-07-11 |
Neal K Vail |
Oral rapamycin nanoparticle preparations
|
|
EP3089737B1
(en)
|
2013-12-31 |
2021-11-03 |
Rapamycin Holdings, LLC |
Oral rapamycin nanoparticle preparations and use
|
|
CA2935167C
(en)
|
2014-01-16 |
2022-02-22 |
Musc Foundation For Research Development |
Targeted nanocarriers for the administration of immunosuppressive agents
|
|
CN106061505A
(zh)
|
2014-02-11 |
2016-10-26 |
诺华股份有限公司 |
用于治疗癌症的含pi3k抑制剂的药物组合
|
|
ES2857226T3
(es)
|
2014-03-15 |
2021-09-28 |
Novartis Ag |
Receptor de antígeno quimérico regulable
|
|
US20170335281A1
(en)
|
2014-03-15 |
2017-11-23 |
Novartis Ag |
Treatment of cancer using chimeric antigen receptor
|
|
CN103848849B
(zh)
*
|
2014-03-24 |
2016-02-24 |
上海医药工业研究院 |
依维莫司的制备工艺
|
|
CA2943609A1
(en)
|
2014-03-27 |
2015-10-01 |
The Brigham And Women's Hospital, Inc. |
Metabolically-activated drug conjugates to overcome resistance in cancer therapy
|
|
AU2015244039B2
(en)
|
2014-04-07 |
2021-10-21 |
Novartis Ag |
Treatment of cancer using anti-CD19 chimeric antigen receptor
|
|
WO2015171723A1
(en)
|
2014-05-06 |
2015-11-12 |
Research Development Foundation |
Methods for treating insulin resistance and for sensitizing patients to glp1 agonist therapy
|
|
CN105254646A
(zh)
*
|
2014-05-28 |
2016-01-20 |
上海博邦医药科技有限公司 |
一种制备依维莫司的方法
|
|
EP3148564B1
(en)
|
2014-06-02 |
2020-01-08 |
Children's Medical Center Corporation |
Methods and compositions for immunomodulation
|
|
JP2017528433A
(ja)
|
2014-07-21 |
2017-09-28 |
ノバルティス アーゲー |
低い免疫増強用量のｍＴＯＲ阻害剤とＣＡＲの組み合わせ
|
|
TWI719942B
(zh)
|
2014-07-21 |
2021-03-01 |
瑞士商諾華公司 |
使用ｃｄ３３嵌合抗原受體治療癌症
|
|
US11542488B2
(en)
|
2014-07-21 |
2023-01-03 |
Novartis Ag |
Sortase synthesized chimeric antigen receptors
|
|
BR112017001183A2
(pt)
|
2014-07-21 |
2017-11-28 |
Novartis Ag |
tratamento de câncer usando receptor de antígeno quimérico anti-bcma humanizado
|
|
EP4205749A1
(en)
|
2014-07-31 |
2023-07-05 |
Novartis AG |
Subset-optimized chimeric antigen receptor-containing cells
|
|
EP3166950A1
(en)
*
|
2014-08-04 |
2017-05-17 |
Cipla Limited |
Process for the synthesis of everolimus and intermediates thereof
|
|
CN117088931A
(zh)
|
2014-08-12 |
2023-11-21 |
莫纳什大学 |
定向淋巴的前药
|
|
AU2015301460B2
(en)
|
2014-08-14 |
2021-04-08 |
Novartis Ag |
Treatment of cancer using GFR alpha-4 chimeric antigen receptor
|
|
MX2017002205A
(es)
|
2014-08-19 |
2017-08-21 |
Novartis Ag |
Receptor quimerico de antigeno (car) anti-cd123 para uso en el tratamiento de cancer.
|
|
PT3524595T
(pt)
|
2014-08-28 |
2022-09-19 |
Eisai R&D Man Co Ltd |
Derivado de quinolina altamente puro e método para produção do mesmo
|
|
CN113620978A
(zh)
|
2014-09-11 |
2021-11-09 |
加利福尼亚大学董事会 |
mTORC1抑制剂
|
|
JP6839074B2
(ja)
|
2014-09-17 |
2021-03-03 |
ノバルティス アーゲー |
養子免疫療法のためのキメラ受容体での細胞毒性細胞のターゲティング
|
|
KR20170068504A
(ko)
|
2014-10-08 |
2017-06-19 |
노파르티스 아게 |
키메라 항원 수용체 요법에 대한 치료 반응성을 예측하는 바이오마커 및 그의 용도
|
|
WO2016066608A1
(en)
|
2014-10-28 |
2016-05-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for treatment of pulmonary cell senescence and peripheral aging
|
|
US10143682B2
(en)
|
2014-10-28 |
2018-12-04 |
Koushi Yamaguchi |
Medicine for improving state of pregnancy, and use thereof
|
|
EP3212194A4
(en)
|
2014-10-29 |
2018-06-20 |
University Of Maryland |
Methods of treating age-related symptoms in mammals and compositions therefor
|
|
CN104478898A
(zh)
*
|
2014-11-18 |
2015-04-01 |
连云港恒运医药科技有限公司 |
依维莫司及其中间体的制备方法
|
|
WO2016135740A1
(en)
|
2015-02-23 |
2016-09-01 |
Natco Pharma Limited |
Process for preparing stable oral compositions of everolimus
|
|
LT3263106T
(lt)
|
2015-02-25 |
2024-01-10 |
Eisai R&D Management Co., Ltd. |
Chinolino darinių kartumo sumažinimo būdas
|
|
KR102662228B1
(ko)
|
2015-03-04 |
2024-05-02 |
머크 샤프 앤드 돔 코포레이션 |
암을 치료하기 위한 pd-1 길항제 및 vegfr/fgfr/ret 티로신 키나제 억제제의 조합
|
|
US9670205B2
(en)
|
2015-03-04 |
2017-06-06 |
Gilead Sciences, Inc. |
Toll like receptor modulator compounds
|
|
AU2016249005B2
(en)
|
2015-04-17 |
2022-06-16 |
Novartis Ag |
Methods for improving the efficacy and expansion of chimeric antigen receptor-expressing cells
|
|
EP3286211A1
(en)
|
2015-04-23 |
2018-02-28 |
Novartis AG |
Treatment of cancer using chimeric antigen receptor and protein kinase a blocker
|
|
CA2986359A1
(en)
|
2015-05-20 |
2016-11-24 |
Novartis Ag |
Pharmaceutical combination of everolimus with dactolisib
|
|
CN104892632B
(zh)
*
|
2015-06-03 |
2017-12-26 |
道中道（菏泽）制药有限公司 |
一种晶体形式的依维莫司及其制备方法
|
|
MX373231B
(es)
|
2015-06-16 |
2020-05-08 |
Eisai R&D Man Co Ltd |
Agente anticancerigeno.
|
|
EP3109250A1
(en)
|
2015-06-23 |
2016-12-28 |
Synbias Pharma AG |
Method for the synthesis of rapamycin derivatives
|
|
WO2017029391A1
(en)
|
2015-08-20 |
2017-02-23 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
New method for treating cancer
|
|
US12220398B2
(en)
|
2015-08-20 |
2025-02-11 |
Eisai R&D Management Co., Ltd. |
Tumor therapeutic agent
|
|
BR112018004296B1
(pt)
|
2015-09-04 |
2020-05-05 |
Primatope Therapeutics Inc |
anticorpos anti-cd40 humanizados e usos dos mesmos
|
|
US11738087B2
(en)
|
2015-09-08 |
2023-08-29 |
Monash University |
Lymph directing prodrugs
|
|
CA3001654A1
(en)
|
2015-11-11 |
2017-05-18 |
Novartis Ag |
Uses of myostatin antagonists, combinations containing them and uses thereof
|
|
CN105566348A
(zh)
*
|
2015-12-31 |
2016-05-11 |
哈药集团技术中心 |
一种依维莫司的制备方法
|
|
WO2017181115A1
(en)
|
2016-04-14 |
2017-10-19 |
Spinnaker Biosciences, Inc. |
Porous silicon materials comprising a metal silicate for delivery of therapeutic agents
|
|
CN109640959B
(zh)
*
|
2016-04-29 |
2023-03-17 |
西奈山伊坎医学院 |
靶向先天免疫系统以诱导长期耐受性及解决动脉粥样硬化中的巨噬细胞累积
|
|
WO2017204215A1
(ja)
|
2016-05-27 |
2017-11-30 |
日本化薬株式会社 |
ラパマイシン又はその誘導体を含有する医薬組成物
|
|
EP3487878A4
(en)
|
2016-07-20 |
2020-03-25 |
University of Utah Research Foundation |
CD229-CAR-T CELLS AND METHOD FOR USE THEREOF
|
|
WO2018045150A1
(en)
|
2016-09-02 |
2018-03-08 |
Gilead Sciences, Inc. |
4,6-diamino-pyrido[3,2-d]pyrimidine derivaties as toll like receptor modulators
|
|
AU2017318601B2
(en)
|
2016-09-02 |
2020-09-03 |
Gilead Sciences, Inc. |
Toll like receptor modulator compounds
|
|
BR112019006781A2
(pt)
|
2016-10-07 |
2019-07-30 |
Novartis Ag |
receptores de antígeno quiméricos para o tratamento de câncer
|
|
CN110114070A
(zh)
|
2016-11-23 |
2019-08-09 |
诺华公司 |
使用依维莫司(everolimus)、达托里昔布(dactolisib)或二者增强免疫反应的方法
|
|
US20200081010A1
(en)
|
2016-12-02 |
2020-03-12 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Methods and compositions for diagnosing renal cell carcinoma
|
|
CN110366550A
(zh)
|
2016-12-22 |
2019-10-22 |
美国安进公司 |
作为用于治疗肺癌、胰腺癌或结直肠癌的KRAS G12C抑制剂的苯并异噻唑、异噻唑并[3,4-b]吡啶、喹唑啉、酞嗪、吡啶并[2,3-d]哒嗪和吡啶并[2,3-d]嘧啶衍生物
|
|
GB201701087D0
(en)
|
2017-01-23 |
2017-03-08 |
Univ Leuven Kath |
Novel prodrugs of mizoribine
|
|
US12303505B2
(en)
|
2017-02-08 |
2025-05-20 |
Eisai R&D Management Co., Ltd. |
Tumor-treating pharmaceutical composition
|
|
JP2020507632A
(ja)
*
|
2017-02-10 |
2020-03-12 |
マウント タム セラピューティクス, インコーポレイテッドMount Tam Therapeutics, Inc. |
ラパマイシン類似体
|
|
EP3615055A1
(en)
|
2017-04-28 |
2020-03-04 |
Novartis AG |
Cells expressing a bcma-targeting chimeric antigen receptor, and combination therapy with a gamma secretase inhibitor
|
|
US20210154372A1
(en)
|
2017-05-15 |
2021-05-27 |
C.R. Bard, Inc. |
Medical device with drug-eluting coating and intermediate layer
|
|
RU2019134940A
(ru)
|
2017-05-16 |
2021-06-16 |
Эйсай Ар Энд Ди Менеджмент Ко., Лтд. |
Лечение гепатоцеллюлярной карциномы
|
|
AU2018273356B2
(en)
|
2017-05-22 |
2021-09-16 |
Amgen Inc. |
KRAS G12C inhibitors and methods of using the same
|
|
WO2019002168A1
(en)
|
2017-06-26 |
2019-01-03 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
METHODS AND PHARMACEUTICAL COMPOSITIONS FOR TREATING OLMSTED SYNDROME
|
|
EP3652306A1
(en)
|
2017-07-13 |
2020-05-20 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for increasing expansion and immunosuppressive capacity of a population of cd8+cd45rclow/-tregs
|
|
CA3077739A1
(en)
|
2017-08-29 |
2019-03-07 |
Puretech Lyt, Inc. |
Lymphatic system-directing lipid prodrugs
|
|
US11883497B2
(en)
|
2017-08-29 |
2024-01-30 |
Puretech Lyt, Inc. |
Lymphatic system-directing lipid prodrugs
|
|
AU2018329920B2
(en)
|
2017-09-08 |
2022-12-01 |
Amgen Inc. |
Inhibitors of KRAS G12C and methods of using the same
|
|
AR112834A1
(es)
|
2017-09-26 |
2019-12-18 |
Novartis Ag |
Derivados de rapamicina
|
|
CN108047265A
(zh)
*
|
2017-11-24 |
2018-05-18 |
成都海创药业有限公司 |
一种依维莫司中间体的制备纯化方法
|
|
US11304954B2
(en)
|
2017-12-19 |
2022-04-19 |
Puretech Lyt, Inc. |
Lipid prodrugs of mycophenolic acid and uses thereof
|
|
US11608345B1
(en)
|
2017-12-19 |
2023-03-21 |
Puretech Lyt, Inc. |
Lipid prodrugs of rapamycin and its analogs and uses thereof
|
|
US10596165B2
(en)
|
2018-02-12 |
2020-03-24 |
resTORbio, Inc. |
Combination therapies
|
|
WO2019210153A1
(en)
|
2018-04-27 |
2019-10-31 |
Novartis Ag |
Car t cell therapies with enhanced efficacy
|
|
IL312291A
(en)
|
2018-05-01 |
2024-06-01 |
Revolution Medicines Inc |
C-26-linked rapamycin analogs as MTOR inhibitors
|
|
MX2020011565A
(es)
|
2018-05-01 |
2021-01-29 |
Revolution Medicines Inc |
Analogos de rapamicina ligados a c40, c28 y c-32 como inhibidores de mtor.
|
|
EP3788369A1
(en)
|
2018-05-01 |
2021-03-10 |
Novartis Ag |
Biomarkers for evaluating car-t cells to predict clinical outcome
|
|
EP3788053B1
(en)
|
2018-05-04 |
2024-07-10 |
Amgen Inc. |
Kras g12c inhibitors and methods of using the same
|
|
CA3098574A1
(en)
|
2018-05-04 |
2019-11-07 |
Amgen Inc. |
Kras g12c inhibitors and methods of using the same
|
|
MA52564A
(fr)
|
2018-05-10 |
2021-03-17 |
Amgen Inc |
Inhibiteurs de kras g12c pour le traitement du cancer
|
|
JP2021531061A
(ja)
|
2018-05-22 |
2021-11-18 |
インターフェース バイオロジクス，インコーポレーテッド |
薬物を脈管壁に送達するための組成物及び方法
|
|
TWI869346B
(zh)
|
2018-05-30 |
2025-01-11 |
瑞士商諾華公司 |
Ｅｎｔｐｄ２抗體、組合療法、及使用該等抗體和組合療法之方法
|
|
US11096939B2
(en)
|
2018-06-01 |
2021-08-24 |
Amgen Inc. |
KRAS G12C inhibitors and methods of using the same
|
|
MX2020012204A
(es)
|
2018-06-11 |
2021-03-31 |
Amgen Inc |
Inhibidores de kras g12c para tratar el cáncer.
|
|
US11285156B2
(en)
|
2018-06-12 |
2022-03-29 |
Amgen Inc. |
Substituted piperazines as KRAS G12C inhibitors
|
|
TWI890660B
(zh)
|
2018-06-13 |
2025-07-21 |
瑞士商諾華公司 |
Bcma 嵌合抗原受體及其用途
|
|
CN108676014A
(zh)
*
|
2018-06-15 |
2018-10-19 |
国药集团川抗制药有限公司 |
纯化依维莫司中间体的方法以及制备依维莫司的方法
|
|
AU2019310040A1
(en)
|
2018-07-23 |
2021-02-11 |
Enclear Therapies, Inc. |
Methods of treating neurological disorders
|
|
AU2019310039A1
(en)
|
2018-07-23 |
2021-02-18 |
Enclear Therapies, Inc. |
Methods of treating neurological disorders
|
|
EP3849545A1
(en)
|
2018-09-10 |
2021-07-21 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Methods for the treatment of neurofibromatosis
|
|
EP3861347B1
(en)
|
2018-10-05 |
2022-12-21 |
Eisai R&D Management Co., Ltd. |
Biomarkers for a combination therapy comprising lenvatinib and everolimus
|
|
EP3880266B1
(en)
|
2018-11-14 |
2025-05-07 |
Lutonix, Inc. |
Medical device with drug-eluting coating on modified device surface
|
|
JP7516029B2
(ja)
|
2018-11-16 |
2024-07-16 |
アムジエン・インコーポレーテツド |
Ｋｒａｓ ｇ１２ｃ阻害剤化合物の重要な中間体の改良合成法
|
|
JP7377679B2
(ja)
|
2018-11-19 |
2023-11-10 |
アムジエン・インコーポレーテツド |
がん治療のためのｋｒａｓｇ１２ｃ阻害剤及び１種以上の薬学的に活性な追加の薬剤を含む併用療法
|
|
AU2019384118B2
(en)
|
2018-11-19 |
2025-06-12 |
Amgen Inc. |
KRAS G12C inhibitors and methods of using the same
|
|
HRP20250197T1
(hr)
|
2018-12-18 |
2025-04-11 |
Novartis Ag |
Derivati rapamicina
|
|
JP7686559B2
(ja)
|
2018-12-20 |
2025-06-02 |
アムジエン・インコーポレーテツド |
Ｋｉｆ１８ａ阻害剤
|
|
JP2022513967A
(ja)
|
2018-12-20 |
2022-02-09 |
アムジエン・インコーポレーテツド |
Ｋｉｆ１８ａ阻害剤として有用なヘテロアリールアミド
|
|
MA54543A
(fr)
|
2018-12-20 |
2022-03-30 |
Amgen Inc |
Inhibiteurs de kif18a
|
|
AU2019401495B2
(en)
|
2018-12-20 |
2025-06-26 |
Amgen Inc. |
Heteroaryl amides useful as KIF18A inhibitors
|
|
US20220040324A1
(en)
|
2018-12-21 |
2022-02-10 |
Daiichi Sankyo Company, Limited |
Combination of antibody-drug conjugate and kinase inhibitor
|
|
IL285067B2
(en)
*
|
2019-01-22 |
2025-02-01 |
Aeovian Pharmaceuticals Inc |
MTORC Modulators and Their Uses
|
|
WO2020163594A1
(en)
|
2019-02-07 |
2020-08-13 |
The Regents Of The University Of California |
Immunophilin binding agents and uses thereof
|
|
MX2021010319A
(es)
|
2019-03-01 |
2021-12-10 |
Revolution Medicines Inc |
Compuestos biciclicos de heteroarilo y usos de estos.
|
|
MX2021010323A
(es)
|
2019-03-01 |
2021-12-10 |
Revolution Medicines Inc |
Compuestos bicíclicos de heterociclilo y usos de este.
|
|
EP3952937A1
(en)
|
2019-04-08 |
2022-02-16 |
Bard Peripheral Vascular, Inc. |
Medical device with drug-eluting coating on modified device surface
|
|
AU2020271894A1
(en)
|
2019-04-11 |
2021-12-02 |
Enclear Therapies, Inc. |
Methods of amelioration of cerebrospinal fluid and devices and systems therefor
|
|
TW202212339A
(zh)
|
2019-04-17 |
2022-04-01 |
美商基利科學股份有限公司 |
類鐸受體調節劑之固體形式
|
|
TWI751516B
(zh)
|
2019-04-17 |
2022-01-01 |
美商基利科學股份有限公司 |
類鐸受體調節劑之固體形式
|
|
EP3738593A1
(en)
|
2019-05-14 |
2020-11-18 |
Amgen, Inc |
Dosing of kras inhibitor for treatment of cancers
|
|
WO2020236947A1
(en)
|
2019-05-21 |
2020-11-26 |
Amgen Inc. |
Solid state forms
|
|
TWI879779B
(zh)
|
2019-06-28 |
2025-04-11 |
美商基利科學股份有限公司 |
類鐸受體調節劑化合物的製備方法
|
|
TW202114681A
(zh)
|
2019-07-02 |
2021-04-16 |
美商ｅＦＦＥＣＴＯＲ醫療公司 |
轉譯抑制劑及其用途
|
|
EP4007638A1
(en)
|
2019-08-02 |
2022-06-08 |
Amgen Inc. |
Pyridine derivatives as kif18a inhibitors
|
|
EP4007753B1
(en)
|
2019-08-02 |
2025-09-24 |
Amgen Inc. |
Kif18a inhibitors
|
|
EP4007752B1
(en)
|
2019-08-02 |
2025-09-24 |
Amgen Inc. |
Kif18a inhibitors
|
|
EP4007756B1
(en)
|
2019-08-02 |
2025-12-24 |
Amgen Inc. |
Kif18a inhibitors
|
|
KR20220054347A
(ko)
|
2019-08-26 |
2022-05-02 |
아비나스 오퍼레이션스, 인코포레이티드 |
에스트로겐 수용체 분해제로서의 테트라히드로나프탈렌 유도체로 유방암을 치료하는 방법
|
|
CN114502590A
(zh)
|
2019-09-18 |
2022-05-13 |
诺华股份有限公司 |
Entpd2抗体、组合疗法、以及使用这些抗体和组合疗法的方法
|
|
US20220402916A1
(en)
|
2019-09-18 |
2022-12-22 |
Merck Sharp & Dohme Corp. |
Small molecule inhibitors of kras g12c mutant
|
|
EP4048671B1
(en)
|
2019-10-24 |
2026-03-18 |
Amgen Inc. |
Pyridopyrimidine derivatives useful as kras g12c and kras g12d inhibitors in the treatment of cancer
|
|
UA129778C2
(uk)
|
2019-10-28 |
2025-07-30 |
Мерк Шарп Енд Доум Елелсі |
Низькомолекулярні інгібітори g12c-мутантного kras
|
|
US20230023023A1
(en)
|
2019-10-31 |
2023-01-26 |
Taiho Pharmaceutical Co., Ltd. |
4-aminobut-2-enamide derivatives and salts thereof
|
|
AU2020377925A1
(en)
|
2019-11-04 |
2022-05-05 |
Revolution Medicines, Inc. |
Ras inhibitors
|
|
IL322454A
(en)
|
2019-11-04 |
2025-09-01 |
Revolution Medicines Inc |
ras inhibitors
|
|
TW202132316A
(zh)
|
2019-11-04 |
2021-09-01 |
美商銳新醫藥公司 |
Ｒａｓ抑制劑
|
|
CA3156359A1
(en)
|
2019-11-08 |
2021-05-14 |
Adrian Liam Gill |
Bicyclic heteroaryl compounds and uses thereof
|
|
JP7837865B2
(ja)
|
2019-11-14 |
2026-03-31 |
アムジエン・インコーポレーテツド |
Ｋｒａｓ ｇ１２ｃ阻害剤化合物の改良合成法
|
|
JP2023501528A
(ja)
|
2019-11-14 |
2023-01-18 |
アムジエン・インコーポレーテツド |
Ｋｒａｓ ｇ１２ｃ阻害剤化合物の改善された合成
|
|
EP4065231A1
(en)
|
2019-11-27 |
2022-10-05 |
Revolution Medicines, Inc. |
Covalent ras inhibitors and uses thereof
|
|
WO2021106231A1
(en)
|
2019-11-29 |
2021-06-03 |
Taiho Pharmaceutical Co., Ltd. |
A compound having inhibitory activity against kras g12d mutation
|
|
CN118767143A
(zh)
|
2019-12-12 |
2024-10-15 |
听治疗有限责任公司 |
用于预防和治疗听力损失的组合物和方法
|
|
WO2021142026A1
(en)
|
2020-01-07 |
2021-07-15 |
Revolution Medicines, Inc. |
Shp2 inhibitor dosing and methods of treating cancer
|
|
IL295362A
(en)
|
2020-02-05 |
2022-10-01 |
Puretech Lyt Inc |
Lipid drug inhibitors of neurosteroids
|
|
WO2021215544A1
(en)
|
2020-04-24 |
2021-10-28 |
Taiho Pharmaceutical Co., Ltd. |
Kras g12d protein inhibitors
|
|
WO2021215545A1
(en)
|
2020-04-24 |
2021-10-28 |
Taiho Pharmaceutical Co., Ltd. |
Anticancer combination therapy with n-(1-acryloyl-azetidin-3-yl)-2-((1h-indazol-3-yl)amino)methyl)-1h-imidazole-5-carboxamide inhibitor of kras-g12c
|
|
EP4183395A4
(en)
|
2020-07-15 |
2024-07-24 |
Taiho Pharmaceutical Co., Ltd. |
PYRIMIDINE COMPOUND-CONTAINING COMBINATION FOR USE IN TUMOR TREATMENT
|
|
US20250195521A1
(en)
|
2020-09-03 |
2025-06-19 |
Revolution Medicines, Inc. |
Use of sos1 inhibitors to treat malignancies with shp2 mutations
|
|
CA3194067A1
(en)
|
2020-09-15 |
2022-03-24 |
Revolution Medicines, Inc. |
Ras inhibitors
|
|
US12329930B2
(en)
|
2020-09-29 |
2025-06-17 |
Enclear Therapies, Inc. |
Subarachnoid fluid management method and system
|
|
JP7849366B2
(ja)
|
2020-12-22 |
2026-04-21 |
キル・レガー・セラピューティクス・インコーポレーテッド |
Ｓｏｓ１阻害剤およびその使用
|
|
AU2022239614A1
(en)
|
2021-03-19 |
2023-10-12 |
Icahn School Of Medicine At Mount Sinai |
Compounds for regulating trained immunity, and their methods of use
|
|
KR20240017811A
(ko)
|
2021-05-05 |
2024-02-08 |
레볼루션 메디슨즈, 인크. |
암의 치료를 위한 ras 억제제
|
|
TW202309052A
(zh)
|
2021-05-05 |
2023-03-01 |
美商銳新醫藥公司 |
Ｒａｓ抑制劑
|
|
JP2024516450A
(ja)
|
2021-05-05 |
2024-04-15 |
レボリューション メディシンズ インコーポレイテッド |
共有結合性ｒａｓ阻害剤及びその使用
|
|
EP4347041A1
(en)
|
2021-05-28 |
2024-04-10 |
Taiho Pharmaceutical Co., Ltd. |
Small molecule inhibitors of kras mutated proteins
|
|
WO2023288046A1
(en)
|
2021-07-15 |
2023-01-19 |
President And Fellows Of Harvard College |
Compositions and methods relating to cells with adhered particles
|
|
AR127308A1
(es)
|
2021-10-08 |
2024-01-10 |
Revolution Medicines Inc |
Inhibidores ras
|
|
US20240294548A1
(en)
|
2021-10-12 |
2024-09-05 |
Peloton Therapeutics Inc. |
Tricyclic sultams and sulfamides as antitumor agents
|
|
CN119212994A
(zh)
|
2021-12-17 |
2024-12-27 |
建新公司 |
作为shp2抑制剂的吡唑并吡嗪化合物
|
|
EP4227307A1
(en)
|
2022-02-11 |
2023-08-16 |
Genzyme Corporation |
Pyrazolopyrazine compounds as shp2 inhibitors
|
|
KR20240156373A
(ko)
|
2022-03-07 |
2024-10-29 |
암젠 인크 |
4-메틸-2-프로판-2-일-피리딘-3-카르보니트릴의 제조 방법
|
|
JP2025510572A
(ja)
|
2022-03-08 |
2025-04-15 |
レボリューション メディシンズ インコーポレイテッド |
免疫不応性肺癌を治療するための方法
|
|
CA3256390A1
(en)
|
2022-05-25 |
2023-11-30 |
Revolution Medicines, Inc. |
CANCER TREATMENT METHODS USING AN MTOR INHIBITOR
|
|
WO2023240263A1
(en)
|
2022-06-10 |
2023-12-14 |
Revolution Medicines, Inc. |
Macrocyclic ras inhibitors
|
|
US20260000658A1
(en)
|
2022-07-06 |
2026-01-01 |
Institut National de la Santé et de la Recherche Médicale |
Methods for the treatment of proliferative glomerulonephritis
|
|
EP4565217A1
(en)
|
2022-08-04 |
2025-06-11 |
Institut National de la Santé et de la Recherche Médicale |
Methods for the treatment of lymphoproliferative disorders
|
|
AU2023358792A1
(en)
|
2022-10-14 |
2025-04-17 |
Black Diamond Therapeutics, Inc. |
Methods of treating cancers using isoquinoline or 6-aza-quinoline derivatives
|
|
WO2024100236A1
(en)
|
2022-11-11 |
2024-05-16 |
Astrazeneca Ab |
Combination therapies for the treatment of cancer
|
|
WO2024167904A1
(en)
|
2023-02-07 |
2024-08-15 |
Arvinas Operations, Inc. |
Dosage regimens of estrogen receptor degraders in combination with an mtor inhibitor
|
|
AU2024241633A1
(en)
|
2023-03-30 |
2025-11-06 |
Revolution Medicines, Inc. |
Compositions for inducing ras gtp hydrolysis and uses thereof
|
|
AR132338A1
(es)
|
2023-04-07 |
2025-06-18 |
Revolution Medicines Inc |
Inhibidores de ras
|
|
CR20250420A
(es)
|
2023-04-07 |
2025-11-20 |
Revolution Medicines Inc |
Inhibidores macrocíclicos de ras
|
|
CN121100123A
(zh)
|
2023-04-14 |
2025-12-09 |
锐新医药公司 |
Ras抑制剂的结晶形式
|
|
CN121464140A
(zh)
|
2023-04-14 |
2026-02-03 |
锐新医药公司 |
Ras抑制剂的结晶形式、含有其的组合物及其使用方法
|
|
TW202508595A
(zh)
|
2023-05-04 |
2025-03-01 |
美商銳新醫藥公司 |
用於ｒａｓ相關疾病或病症之組合療法
|
|
CN116813641A
(zh)
*
|
2023-06-09 |
2023-09-29 |
杭州华东医药集团康润制药有限公司 |
一种依维莫司的制备方法
|
|
US20250049810A1
(en)
|
2023-08-07 |
2025-02-13 |
Revolution Medicines, Inc. |
Methods of treating a ras protein-related disease or disorder
|
|
WO2025043187A1
(en)
|
2023-08-24 |
2025-02-27 |
Otsuka Pharmaceutical Co., Ltd. |
Fixed dose combinations of cedazuridine and azacitidine
|
|
AU2024360465A1
(en)
|
2023-10-12 |
2026-04-09 |
Revolution Medicines, Inc. |
Macrocyclic ras inhibitors
|
|
AU2024361909A1
(en)
|
2023-10-20 |
2026-03-26 |
Merck Sharp & Dohme Llc |
Small molecule inhibitors of kras proteins
|
|
TW202542151A
(zh)
|
2023-12-22 |
2025-11-01 |
美商銳格醫藥有限公司 |
Ｓｏｓ１抑制劑及其用途
|
|
WO2025171296A1
(en)
|
2024-02-09 |
2025-08-14 |
Revolution Medicines, Inc. |
Ras inhibitors
|
|
TW202547461A
(zh)
|
2024-05-17 |
2025-12-16 |
美商銳新醫藥公司 |
Ｒａｓ抑制劑
|
|
WO2025255438A1
(en)
|
2024-06-07 |
2025-12-11 |
Revolution Medicines, Inc. |
Methods of treating a ras protein-related disease or disorder
|
|
WO2025265060A1
(en)
|
2024-06-21 |
2025-12-26 |
Revolution Medicines, Inc. |
Therapeutic compositions and methods for managing treatment-related effects
|
|
WO2026006747A1
(en)
|
2024-06-28 |
2026-01-02 |
Revolution Medicines, Inc. |
Ras inhibitors
|
|
WO2026015790A1
(en)
|
2024-07-12 |
2026-01-15 |
Revolution Medicines, Inc. |
Methods of treating a ras related disease or disorder
|
|
WO2026015825A1
(en)
|
2024-07-12 |
2026-01-15 |
Revolution Medicines, Inc. |
Use of ras inhibitor for treating pancreatic cancer
|
|
WO2026015801A1
(en)
|
2024-07-12 |
2026-01-15 |
Revolution Medicines, Inc. |
Methods of treating a ras related disease or disorder
|
|
WO2026015796A1
(en)
|
2024-07-12 |
2026-01-15 |
Revolution Medicines, Inc. |
Methods of treating a ras related disease or disorder
|
|
WO2026050446A1
(en)
|
2024-08-29 |
2026-03-05 |
Revolution Medicines, Inc. |
Ras inhibitors
|
|
WO2026072904A2
(en)
|
2024-09-26 |
2026-04-02 |
Revolution Medicines, Inc. |
Compositions and methods for treating lung cancer
|