DE60044717D1 - Kombination von immunsuppressiven substanzen zur behandlung oder vorbeugung von transplantat abstossungen - Google Patents
Kombination von immunsuppressiven substanzen zur behandlung oder vorbeugung von transplantat abstossungenInfo
- Publication number
- DE60044717D1 DE60044717D1 DE60044717T DE60044717T DE60044717D1 DE 60044717 D1 DE60044717 D1 DE 60044717D1 DE 60044717 T DE60044717 T DE 60044717T DE 60044717 T DE60044717 T DE 60044717T DE 60044717 D1 DE60044717 D1 DE 60044717D1
- Authority
- DE
- Germany
- Prior art keywords
- recipient
- prevention
- treatment
- rejection
- xenografts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9910835.9A GB9910835D0 (en) | 1999-05-10 | 1999-05-10 | Organic compounds |
GBGB9925443.5A GB9925443D0 (en) | 1999-10-27 | 1999-10-27 | Organic compounds |
PCT/EP2000/004250 WO2000067773A2 (en) | 1999-05-10 | 2000-05-10 | Combinations of immunosupressive agents for the treatment or prevention of graft rejections |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60044717D1 true DE60044717D1 (de) | 2010-09-02 |
Family
ID=26315533
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60044717T Expired - Lifetime DE60044717D1 (de) | 1999-05-10 | 2000-05-10 | Kombination von immunsuppressiven substanzen zur behandlung oder vorbeugung von transplantat abstossungen |
Country Status (7)
Country | Link |
---|---|
US (5) | US20020132764A1 (de) |
EP (2) | EP1980263A1 (de) |
JP (1) | JP2002544167A (de) |
AT (1) | ATE474590T1 (de) |
AU (1) | AU4565000A (de) |
DE (1) | DE60044717D1 (de) |
WO (1) | WO2000067773A2 (de) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT1208847E (pt) * | 1996-07-30 | 2007-07-24 | Novartis Ag | Composições farmacêuticas para o tratamento da rejeição de transplantes, doenças autoimunes ou inflamatórias compreendendo ciclosporina a e 40-0-(2-hidroxietil)-rapamicina |
AU3095601A (en) | 2000-01-14 | 2001-07-24 | Univ Pennsylvania | O-methylated rapamycin derivatives for alleviation and inhibition of lymphoproliferative disorders |
GB0124953D0 (en) * | 2001-10-17 | 2001-12-05 | Novartis Ag | Organic Compounds |
GB0307553D0 (en) * | 2003-04-01 | 2003-05-07 | Novartis Ag | Organic compounds |
AR045957A1 (es) * | 2003-10-03 | 2005-11-16 | Novartis Ag | Composicion farmaceutica y combinacion |
CN105792775B (zh) | 2013-09-24 | 2019-02-19 | 吉纳生命科学公司 | 用于细胞植入物的气体处理的系统 |
MX2019005676A (es) | 2016-11-15 | 2019-09-10 | Giner Life Sciences Inc | Dispositivo percutáneo de difusión de gases adecuado para su uso con un implante subcutáneo. |
JP7199632B2 (ja) | 2017-05-04 | 2023-01-06 | ガイナー,インク. | 堅牢なインプラント可能なガス送達装置ならびにそれを含む方法、システムおよび装置 |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5178858A (en) * | 1987-12-02 | 1993-01-12 | Reichert Thomas A | Method for prevention of graft versus host disease |
US5135934A (en) | 1990-07-06 | 1992-08-04 | Du Pont Merck Pharmaceutical Company | 3-phenyl-5,6-dihydrobenz(c) acridine-7-carboxylic acids and related compounds as immunosuppressive agents |
EP0661980B1 (de) * | 1991-08-23 | 2003-02-19 | Alberta Research Council | Verfahren und zusammensetzungen zur verhinderung der antikörper-vermittelten abstossung von xenogenen transplantaten |
US5516781A (en) * | 1992-01-09 | 1996-05-14 | American Home Products Corporation | Method of treating restenosis with rapamycin |
GB9221220D0 (en) | 1992-10-09 | 1992-11-25 | Sandoz Ag | Organic componds |
US5843452A (en) * | 1992-11-09 | 1998-12-01 | Pharmagenesis, Inc. | Immunotherapy composition and method |
JP3161604B2 (ja) | 1994-05-13 | 2001-04-25 | プラズマセレクト ゲーエムベーハー テテロウ | 血液中の物質を結合してそれを除去するためのタンパク質を結合させた、無菌かつ発熱物質を含有しないカラム |
US5624946A (en) * | 1994-07-05 | 1997-04-29 | Williams; James | Use of leflunomide to control and reverse chronic allograft rejection |
IL129547A (en) | 1994-10-26 | 2001-01-11 | Novartis Ag | Pharmaceutical compositions comprising a macrolide and an acid |
US5697109A (en) | 1994-10-28 | 1997-12-16 | Barton Medical Corporation | Patient transport system |
US5631282A (en) * | 1995-06-07 | 1997-05-20 | Merck & Co., Inc. | Triterpenes |
BE1009856A5 (fr) | 1995-07-14 | 1997-10-07 | Sandoz Sa | Composition pharmaceutique sous la forme d'une dispersion solide comprenant un macrolide et un vehicule. |
GB9601120D0 (en) | 1996-01-19 | 1996-03-20 | Sandoz Ltd | Organic compounds |
GB9606452D0 (en) * | 1996-03-27 | 1996-06-05 | Sandoz Ltd | Organic compounds |
ID18663A (id) | 1996-04-12 | 1998-04-30 | Novartis Ag | Komposisi farmasi berlapis enterik |
PT1208847E (pt) * | 1996-07-30 | 2007-07-24 | Novartis Ag | Composições farmacêuticas para o tratamento da rejeição de transplantes, doenças autoimunes ou inflamatórias compreendendo ciclosporina a e 40-0-(2-hidroxietil)-rapamicina |
GB9619706D0 (en) | 1996-09-20 | 1996-11-06 | Pharmacia Spa | Synergistic immunosuppressant composition containing a 2,2'-bi-1H-pyrrole comp und |
US5962415A (en) * | 1996-09-20 | 1999-10-05 | Bristol-Myers Squibb Co. | Compositions comprising a peptide inhibitor of nuclear protein translocation and an immunosuppressant and methods of use thereof |
WO1998047915A1 (en) | 1997-04-18 | 1998-10-29 | Novartis Ag | Neoglycoproteins |
DE69832883T2 (de) * | 1997-07-14 | 2006-08-24 | Nippon Meat Packers, Inc. | Transgene schweine |
-
2000
- 2000-05-10 EP EP08158054A patent/EP1980263A1/de not_active Withdrawn
- 2000-05-10 JP JP2000616798A patent/JP2002544167A/ja active Pending
- 2000-05-10 EP EP00927193A patent/EP1181034B1/de not_active Expired - Lifetime
- 2000-05-10 DE DE60044717T patent/DE60044717D1/de not_active Expired - Lifetime
- 2000-05-10 AT AT00927193T patent/ATE474590T1/de active
- 2000-05-10 AU AU45650/00A patent/AU4565000A/en not_active Abandoned
- 2000-05-10 WO PCT/EP2000/004250 patent/WO2000067773A2/en active Application Filing
-
2001
- 2001-11-07 US US10/035,663 patent/US20020132764A1/en not_active Abandoned
-
2005
- 2005-07-11 US US11/178,573 patent/US20050277585A1/en not_active Abandoned
-
2006
- 2006-11-15 US US11/599,814 patent/US20070060511A1/en not_active Abandoned
-
2008
- 2008-04-24 US US12/109,210 patent/US20080199478A1/en not_active Abandoned
-
2011
- 2011-02-11 US US13/025,347 patent/US8435520B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JP2002544167A (ja) | 2002-12-24 |
US20070060511A1 (en) | 2007-03-15 |
ATE474590T1 (de) | 2010-08-15 |
WO2000067773A3 (en) | 2001-06-28 |
US20080199478A1 (en) | 2008-08-21 |
US8435520B2 (en) | 2013-05-07 |
WO2000067773A2 (en) | 2000-11-16 |
US20110142953A1 (en) | 2011-06-16 |
EP1181034B1 (de) | 2010-07-21 |
EP1181034A2 (de) | 2002-02-27 |
EP1980263A1 (de) | 2008-10-15 |
US20050277585A1 (en) | 2005-12-15 |
AU4565000A (en) | 2000-11-21 |
US20020132764A1 (en) | 2002-09-19 |
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