ATE474590T1 - Kombination von immunsuppressiven substanzen zur behandlung oder vorbeugung von transplantat abstossungen - Google Patents

Kombination von immunsuppressiven substanzen zur behandlung oder vorbeugung von transplantat abstossungen

Info

Publication number
ATE474590T1
ATE474590T1 AT00927193T AT00927193T ATE474590T1 AT E474590 T1 ATE474590 T1 AT E474590T1 AT 00927193 T AT00927193 T AT 00927193T AT 00927193 T AT00927193 T AT 00927193T AT E474590 T1 ATE474590 T1 AT E474590T1
Authority
AT
Austria
Prior art keywords
recipient
prevention
rejection
treatment
xenografts
Prior art date
Application number
AT00927193T
Other languages
English (en)
Inventor
Hendrik Schuurman
Emanuele Cozzi
Francoise Richard
Guy Taccard
David White
Peter Friend
John Wallwork
Paolo Brenner
Original Assignee
Paolo Brenner
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9910835.9A external-priority patent/GB9910835D0/en
Priority claimed from GBGB9925443.5A external-priority patent/GB9925443D0/en
Application filed by Paolo Brenner filed Critical Paolo Brenner
Application granted granted Critical
Publication of ATE474590T1 publication Critical patent/ATE474590T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT00927193T 1999-05-10 2000-05-10 Kombination von immunsuppressiven substanzen zur behandlung oder vorbeugung von transplantat abstossungen ATE474590T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9910835.9A GB9910835D0 (en) 1999-05-10 1999-05-10 Organic compounds
GBGB9925443.5A GB9925443D0 (en) 1999-10-27 1999-10-27 Organic compounds
PCT/EP2000/004250 WO2000067773A2 (en) 1999-05-10 2000-05-10 Combinations of immunosupressive agents for the treatment or prevention of graft rejections

Publications (1)

Publication Number Publication Date
ATE474590T1 true ATE474590T1 (de) 2010-08-15

Family

ID=26315533

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00927193T ATE474590T1 (de) 1999-05-10 2000-05-10 Kombination von immunsuppressiven substanzen zur behandlung oder vorbeugung von transplantat abstossungen

Country Status (7)

Country Link
US (5) US20020132764A1 (de)
EP (2) EP1181034B1 (de)
JP (1) JP2002544167A (de)
AT (1) ATE474590T1 (de)
AU (1) AU4565000A (de)
DE (1) DE60044717D1 (de)
WO (1) WO2000067773A2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6239124B1 (en) * 1996-07-30 2001-05-29 Novartis Ag Pharmaceutical compositions for the treatment of transplant rejection or autoimmune or inflammatory conditions comprising cyclosporin A and 40-0-(2-hydroxyethyl)-rapamycin
EP2298299A3 (de) 2000-01-14 2012-02-29 The Trustees Of The University Of Pennsylvania O-methylierte Rapamycinderivate zur Linderung und Verhinderung von lymphoproliferativen Erkrankungen
GB0124953D0 (en) * 2001-10-17 2001-12-05 Novartis Ag Organic Compounds
GB0307553D0 (en) * 2003-04-01 2003-05-07 Novartis Ag Organic compounds
AR045957A1 (es) * 2003-10-03 2005-11-16 Novartis Ag Composicion farmaceutica y combinacion
JP6749239B2 (ja) 2013-09-24 2020-09-02 ガイナー ライフ サイエンシズ，インク． 細胞インプラントのガス処理用システム
EP3541449B1 (de) 2016-11-15 2021-11-10 Giner Life Sciences, Inc. Perkutane gasdiffusionsvorrichtung zur verwendung mit einem subkutanen implantat
US11642501B2 (en) 2017-05-04 2023-05-09 Giner, Inc. Robust, implantable gas delivery device and methods, systems and devices including same

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5178858A (en) * 1987-12-02 1993-01-12 Reichert Thomas A Method for prevention of graft versus host disease
US5135934A (en) 1990-07-06 1992-08-04 Du Pont Merck Pharmaceutical Company 3-phenyl-5,6-dihydrobenz(c) acridine-7-carboxylic acids and related compounds as immunosuppressive agents
ATE232730T1 (de) 1991-08-23 2003-03-15 Alberta Res Council Verfahren und zusammensetzungen zur verhinderung der antikörper-vermittelten abstossung von xenogenen transplantaten
US5516781A (en) * 1992-01-09 1996-05-14 American Home Products Corporation Method of treating restenosis with rapamycin
GB9221220D0 (en) 1992-10-09 1992-11-25 Sandoz Ag Organic componds
US5843452A (en) * 1992-11-09 1998-12-01 Pharmagenesis, Inc. Immunotherapy composition and method
ATE294959T1 (de) 1994-05-13 2005-05-15 Miltenyi Biotec Gmbh An protein gebundene sterile und pyrogenfreie säulen zum binden und entfernen von substanzen aus blut
US5624946A (en) * 1994-07-05 1997-04-29 Williams; James Use of leflunomide to control and reverse chronic allograft rejection
IL115742A (en) 1994-10-26 2000-06-01 Novartis Ag Pharmaceutical compositions comprising a difficultly soluble active agent a hydrophilic phase a lipophilic phase and a surfactant
US5697109A (en) 1994-10-28 1997-12-16 Barton Medical Corporation Patient transport system
US5631282A (en) * 1995-06-07 1997-05-20 Merck & Co., Inc. Triterpenes
BE1009856A5 (fr) 1995-07-14 1997-10-07 Sandoz Sa Composition pharmaceutique sous la forme d'une dispersion solide comprenant un macrolide et un vehicule.
GB9601120D0 (en) 1996-01-19 1996-03-20 Sandoz Ltd Organic compounds
GB9606452D0 (en) * 1996-03-27 1996-06-05 Sandoz Ltd Organic compounds
ID18663A (id) * 1996-04-12 1998-04-30 Novartis Ag Komposisi farmasi berlapis enterik
US6239124B1 (en) * 1996-07-30 2001-05-29 Novartis Ag Pharmaceutical compositions for the treatment of transplant rejection or autoimmune or inflammatory conditions comprising cyclosporin A and 40-0-(2-hydroxyethyl)-rapamycin
US5962415A (en) * 1996-09-20 1999-10-05 Bristol-Myers Squibb Co. Compositions comprising a peptide inhibitor of nuclear protein translocation and an immunosuppressant and methods of use thereof
GB9619706D0 (en) 1996-09-20 1996-11-06 Pharmacia Spa Synergistic immunosuppressant composition containing a 2,2'-bi-1H-pyrrole comp und
ES2268776T3 (es) 1997-04-18 2007-03-16 Novartis Ag Neoglicoproteinas.
EP1004238B1 (de) 1997-07-14 2005-12-21 Nippon Meat Packers, Inc. Transgene schweine

Also Published As

Publication number Publication date
WO2000067773A2 (en) 2000-11-16
JP2002544167A (ja) 2002-12-24
AU4565000A (en) 2000-11-21
US20020132764A1 (en) 2002-09-19
WO2000067773A3 (en) 2001-06-28
US20110142953A1 (en) 2011-06-16
EP1181034B1 (de) 2010-07-21
US20070060511A1 (en) 2007-03-15
US20080199478A1 (en) 2008-08-21
US20050277585A1 (en) 2005-12-15
EP1181034A2 (de) 2002-02-27
DE60044717D1 (de) 2010-09-02
EP1980263A1 (de) 2008-10-15
US8435520B2 (en) 2013-05-07

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