ATE482712T1 - Überstände von mesenchymstammzellen zur vorbeugung und behandlung von immunantworten in transplantationen - Google Patents
Überstände von mesenchymstammzellen zur vorbeugung und behandlung von immunantworten in transplantationenInfo
- Publication number
- ATE482712T1 ATE482712T1 AT00974007T AT00974007T ATE482712T1 AT E482712 T1 ATE482712 T1 AT E482712T1 AT 00974007 T AT00974007 T AT 00974007T AT 00974007 T AT00974007 T AT 00974007T AT E482712 T1 ATE482712 T1 AT E482712T1
- Authority
- AT
- Austria
- Prior art keywords
- mesenchymal stem
- immune response
- transplantations
- preventing
- stem cell
- Prior art date
Links
- 210000002901 mesenchymal stem cell Anatomy 0.000 title abstract 4
- 230000028993 immune response Effects 0.000 title abstract 3
- 239000006228 supernatant Substances 0.000 title 1
- 208000009329 Graft vs Host Disease Diseases 0.000 abstract 1
- 208000024908 graft versus host disease Diseases 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/001—Preparations to induce tolerance to non-self, e.g. prior to transplantation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/122—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells for inducing tolerance or supression of immune responses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5158—Antigen-pulsed cells, e.g. T-cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/24—Interferons [IFN]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
- C12N2502/1352—Mesenchymal stem cells
- C12N2502/1358—Bone marrow mesenchymal stem cells (BM-MSC)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Developmental Biology & Embryology (AREA)
- Cell Biology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Hematology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Transplantation (AREA)
- General Chemical & Material Sciences (AREA)
- Rheumatology (AREA)
- Virology (AREA)
- Mycology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/427,333 US6368636B1 (en) | 1998-03-18 | 1999-10-26 | Mesenchymal stem cells for prevention and treatment of immune responses in transplantation |
PCT/US2000/029815 WO2001032189A1 (en) | 1999-10-26 | 2000-10-26 | Supernatant from mesenchymal stem cells for prevention and treatment of immune responses in transplantation |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE482712T1 true ATE482712T1 (de) | 2010-10-15 |
Family
ID=23694416
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00974007T ATE482712T1 (de) | 1999-10-26 | 2000-10-26 | Überstände von mesenchymstammzellen zur vorbeugung und behandlung von immunantworten in transplantationen |
Country Status (10)
Country | Link |
---|---|
US (2) | US6368636B1 (de) |
EP (2) | EP2269616A3 (de) |
JP (1) | JP2004506598A (de) |
AT (1) | ATE482712T1 (de) |
AU (1) | AU782064B2 (de) |
CA (1) | CA2387542C (de) |
DE (1) | DE60045034D1 (de) |
ES (1) | ES2351203T3 (de) |
PT (1) | PT1223956E (de) |
WO (1) | WO2001032189A1 (de) |
Families Citing this family (110)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4441115B2 (ja) * | 1998-03-13 | 2010-03-31 | オシリス セラピューティクス,インコーポレイテッド | ヒト非自己間葉幹細胞を使用する方法と利用 |
US20040265285A1 (en) * | 1999-04-15 | 2004-12-30 | Monash University | Normalization of defective T cell responsiveness through manipulation of thymic regeneration |
US20050042679A1 (en) * | 1999-04-15 | 2005-02-24 | Monash University | Diagnostic indicator of thymic function |
AU2003901668A0 (en) | 2003-03-28 | 2003-05-01 | Medvet Science Pty. Ltd. | Non-haemopoietic precursor cells |
AUPQ147799A0 (en) * | 1999-07-07 | 1999-07-29 | Medvet Science Pty. Ltd. | Mesenchymal precursor cell |
US7670628B2 (en) * | 1999-07-07 | 2010-03-02 | Angioblast Systems, Inc. | Mesenchymal precursor cell |
US8062675B2 (en) * | 1999-07-07 | 2011-11-22 | Angioblast Systems, Inc. | Mesenchymal precursor cell |
US20050158289A1 (en) * | 1999-07-07 | 2005-07-21 | Simmons Paul J. | Mesenchymal precursor cell and use thereof in the repair of bone defects and fractures in mammals |
US8147824B2 (en) | 1999-08-05 | 2012-04-03 | Athersys, Inc. | Immunomodulatory properties of multipotent adult progenitor cells and uses thereof |
ATE460475T1 (de) * | 2000-04-11 | 2010-03-15 | Univ Southern California | Methode zur verhinderung der transplantatabstossung unter verwendung von tgf- beta zur induktion von t-suppressorzellen |
US20060088512A1 (en) * | 2001-10-15 | 2006-04-27 | Monash University | Treatment of T cell disorders |
KR20040029311A (ko) * | 2000-11-22 | 2004-04-06 | 제론 코포레이션 | 다능성 줄기 세포의 동종이식편의 내성화 |
US7311905B2 (en) | 2002-02-13 | 2007-12-25 | Anthrogenesis Corporation | Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells |
US20080152629A1 (en) * | 2000-12-06 | 2008-06-26 | James Edinger | Placental stem cell populations |
AU2020902A (en) * | 2000-12-06 | 2002-06-18 | Robert J Hariri | Method of collecting placental stem cells background of the invention |
IL157350A0 (en) * | 2001-02-14 | 2004-02-19 | Anthrogenesis Corp | Post-partum mammalian placenta, its use and placental stem cells therefrom |
NZ528035A (en) * | 2001-02-14 | 2005-07-29 | Robert J Hariri | Renovation and repopulation of decellularized tissues and cadaveric organs by stem cells |
EP1435977A4 (de) * | 2001-09-19 | 2005-06-08 | Ford Henry Health System | Herztransplantation von stammzellen zur behandlung von herzinsuffizienz |
CA2477411A1 (en) * | 2002-03-02 | 2003-09-12 | Board Of Regents, The University Of Texas | Local production and/or delivery of anti-cancer agents by stromal cell precursors |
AU2003240512B2 (en) | 2002-06-04 | 2009-11-05 | The Board Of Trustees Of The Leland Stanford Junior University | Device and method for rapid aspiration and collection of body tissue from within an enclosed body space |
WO2004046312A2 (en) * | 2002-11-15 | 2004-06-03 | The Board Of Trustees Of The University Of Illinois | Methods for in vitro expansion of hematopoietic stem cells |
US20040101959A1 (en) * | 2002-11-21 | 2004-05-27 | Olga Marko | Treatment of tissue with undifferentiated mesenchymal cells |
AU2003289907A1 (en) * | 2002-11-28 | 2004-06-18 | Genethor Gmbh | Cells not presenting antigen for suppressing pathological immune reactions |
WO2004090112A2 (en) * | 2003-04-01 | 2004-10-21 | United States Of America Department Of Veteran's Affairs | Stem-cell, precursor cell, or target cell-based treatment of multi-organ failure and renal dysfunction |
GB0321337D0 (en) * | 2003-09-11 | 2003-10-15 | Massone Mobile Advertising Sys | Method and system for distributing advertisements |
US20080279812A1 (en) * | 2003-12-05 | 2008-11-13 | Norwood Immunology, Ltd. | Disease Prevention and Vaccination Prior to Thymic Reactivation |
EP3461884A1 (de) | 2004-03-22 | 2019-04-03 | Mesoblast International Sàrl | Mesenchymale stammzellen und verwendungen davon |
ES2645018T3 (es) * | 2004-03-22 | 2017-12-01 | Mesoblast International Sàrl | Células madre mesenquimales y usos para estas |
AU2005241008C1 (en) * | 2004-04-23 | 2010-11-04 | Bioe, Inc. | Multi-Lineage Progenitor Cells |
US7622108B2 (en) * | 2004-04-23 | 2009-11-24 | Bioe, Inc. | Multi-lineage progenitor cells |
US20050265980A1 (en) * | 2004-05-14 | 2005-12-01 | Becton, Dickinson And Company | Cell culture environments for the serum-free expansion of mesenchymal stem cells |
CA2504451A1 (en) * | 2004-08-10 | 2006-02-10 | Geron Corporation | Dendritic cell vaccines for treating cancer made from embryonic stem cells |
US20060045872A1 (en) | 2004-08-25 | 2006-03-02 | Universidad Autonoma De Madrid Ciudad Universitaria de Cantoblanco | Use of adipose tissue-derived stromal stem cells in treating fistula |
MX2007004235A (es) * | 2004-09-10 | 2007-10-03 | Cognate Therapeutics Inc | Celulas estromales de higado para la prevencion y tratamiento de respuestas inmunes en transplantacion. |
CA2581237C (en) | 2004-09-24 | 2018-11-06 | Angioblast Systems, Inc. | Method of enhancing proliferation and/or survival of mesenchymal precursor cells (mpc) |
CA2512667A1 (en) * | 2005-01-07 | 2006-07-07 | Takahiro Ochiya | Human hepatocyte-like cells and uses thereof |
US20060153819A1 (en) * | 2005-01-11 | 2006-07-13 | Cognate Therapeutics, Inc. | Bone marrow stromal cells for immunoprotection of transplanted neural stem cells |
CA2608048A1 (en) * | 2005-05-10 | 2006-11-16 | United States Of America Department Of Veteran's Affairs | Therapy of kidney diseases and multiorgan failure with mesenchymal stem cells and mesenchymal stem cell conditioned media |
WO2008020815A1 (en) * | 2006-08-15 | 2008-02-21 | Agency For Science, Technology And Research | Mesenchymal stem cell conditioned medium |
SI1926813T2 (sl) | 2005-09-23 | 2019-11-29 | Tigenix S A U | Celična populacija z imunoregulatorno aktivnostjo, postopek za izolacijo in uporabe |
US20070082328A1 (en) * | 2005-09-27 | 2007-04-12 | Donnie Rudd | Rotatable time varying electromagnetic force bioreactor and method of using the same |
AU2006304277B2 (en) | 2005-10-13 | 2012-07-05 | Celularity Inc. | Immunomodulation using placental stem cells |
US11000546B2 (en) | 2005-11-09 | 2021-05-11 | Athersys, Inc. | Immunomodulatory properties of MAPCs and uses thereof |
US10117900B2 (en) | 2005-11-09 | 2018-11-06 | Athersys, Inc. | MAPC treatment of brain injuries and diseases |
EP1976978A2 (de) | 2005-12-29 | 2008-10-08 | Anthrogenesis Corporation | Cokultur von plazentastammzellen und stammzellen anderen ursprungs |
DK2471905T3 (da) | 2005-12-29 | 2019-01-02 | Celularity Inc | Placentastamcellepopulationer |
MX2008008774A (es) | 2006-01-13 | 2008-09-26 | Osiris Therapeutics Inc | Celulas madre mesenquimales que expresan los receptores tnf-alfa. |
US11992507B2 (en) | 2006-01-23 | 2024-05-28 | Abt Holding Company | MAPC therapeutics without adjunctive immunosuppressive treatment |
CA2646491A1 (en) * | 2006-04-17 | 2007-10-25 | Bioe, Inc. | Differentiation of multi-lineage progenitor cells to respiratory epithelial cells |
HUE059011T2 (hu) | 2006-05-31 | 2022-09-28 | Childrens Medical Center | Immunmodulátorként szolgáló ABC5-pozitív mezenchimális õssejtek |
JP2009539378A (ja) * | 2006-06-09 | 2009-11-19 | アントフロゲネシス コーポレーション | 胎盤環境及び幹細胞を培養するためのその使用 |
US7993918B2 (en) * | 2006-08-04 | 2011-08-09 | Anthrogenesis Corporation | Tumor suppression using placental stem cells |
DK2314300T3 (da) | 2006-11-03 | 2014-01-06 | Aastrom Biosciences Inc | Populationer af blandede celler til vævsreparation og separationsteknik til cellebehandling |
JP5979811B2 (ja) | 2007-02-12 | 2016-08-31 | アンスロジェネシス コーポレーション | 胎盤幹細胞を使用した炎症性疾患の治療 |
EP2155860B1 (de) | 2007-05-03 | 2014-08-27 | The Brigham and Women's Hospital, Inc. | Multipotente stammzellen und ihre verwendung |
TWM322542U (en) * | 2007-05-23 | 2007-11-21 | Universal Scient Ind Co Ltd | Testing machine |
KR20100035648A (ko) * | 2007-06-15 | 2010-04-05 | 가넷 바이오쎄라퓨틱스 인크. | 체외 배양 및 증식 자기재생성 집락 형성 세포를 이용한 질환 및 장애 치료방법 |
CN101835479A (zh) * | 2007-07-25 | 2010-09-15 | 佰欧益有限公司 | 多系祖细胞分化为软骨细胞 |
NZ584458A (en) | 2007-09-28 | 2012-09-28 | Anthrogenesis Corp | Tumor suppression using human placental perfusate and human placenta-derived intermediate natural killer cells |
WO2009050282A1 (en) * | 2007-10-17 | 2009-04-23 | Txcell | Tr1 cells, mesenchymal stem cells and uses thereof |
US9011840B2 (en) * | 2008-03-14 | 2015-04-21 | The Board Of Trustees Of The University Of Illinois | Activated mesenchymal stem cells for wound healing and impaired tissue regeneration |
WO2009114860A2 (en) * | 2008-03-14 | 2009-09-17 | The Board Of Trustees Of The University Of Illinois | Activated mesenchymal stem cells for the prevention and repair of inflammatory states |
WO2009134429A2 (en) * | 2008-05-02 | 2009-11-05 | Massachusetts Institute Of Technology | Methods and compositions for modulating immunological tolerance |
CA2724839A1 (en) * | 2008-05-21 | 2009-11-26 | Bioe Llc | Differentiation of multi-lineage progenitor cells to pancreatic cells |
AU2009283216B2 (en) | 2008-08-20 | 2015-04-02 | Celularity Inc. | Improved cell composition and methods of making the same |
KR101903049B1 (ko) * | 2008-08-20 | 2018-11-07 | 안트로제네시스 코포레이션 | 단리된 태반 세포를 사용한 혈종 또는 혈관경련수축 치료 |
MX339068B (es) | 2008-08-22 | 2016-05-10 | Anthrogenesis Corp | Metodos y composiciones para el tratamiento de defectos oseos con poblaciones de celulas placentarias. |
EP3130923B1 (de) | 2008-11-14 | 2020-02-12 | The Brigham and Women's Hospital, Inc. | Therapeutische verfahren im zusammenhang mit krebsstammzellen |
US11542328B2 (en) | 2008-11-14 | 2023-01-03 | The Brigham And Women's Hospital, Inc. | Therapeutic and diagnostic methods relating to cancer stem cells |
WO2010059828A1 (en) | 2008-11-19 | 2010-05-27 | Anthrogenesis Corporation | Amnion derived adherent cells |
RU2570550C2 (ru) * | 2008-11-21 | 2015-12-10 | Антродженезис Корпорейшн | Лечение заболеваний, расстройств или патологических состояний легких с использованием плацентарных клеток |
US9301975B2 (en) | 2009-05-01 | 2016-04-05 | Biocardia, Inc. | Method of preparing autologous cells and method of use for therapy |
US20110020293A1 (en) * | 2009-07-21 | 2011-01-27 | Abt Holding Company | Use of Stem Cells to Reduce Leukocyte Extravasation |
CA2787992A1 (en) * | 2010-01-26 | 2011-08-04 | Anthrogenesis Corporation | Treatment of bone-related cancers using placental stem cells |
KR20190076060A (ko) | 2010-04-07 | 2019-07-01 | 안트로제네시스 코포레이션 | 태반 줄기 세포를 사용한 혈관신생 |
KR20130092394A (ko) | 2010-04-08 | 2013-08-20 | 안트로제네시스 코포레이션 | 태반 줄기 세포를 사용한 사르코이드증의 치료 |
KR101203954B1 (ko) | 2010-04-15 | 2012-11-22 | 서울대학교산학협력단 | 혈관 내피 세포성 중간엽 줄기세포를 포함하는 면역 조절용 조성물 |
WO2011143415A1 (en) | 2010-05-12 | 2011-11-17 | Abt Holding Company | Modulation of splenocytes in cell therapy |
WO2012009422A1 (en) | 2010-07-13 | 2012-01-19 | Anthrogenesis Corporation | Methods of generating natural killer cells |
WO2012048099A2 (en) | 2010-10-08 | 2012-04-12 | Osiris Therapeutics, Inc. | Nanoparticle-loaded cells |
EP2625264B1 (de) | 2010-10-08 | 2022-12-07 | Terumo BCT, Inc. | Verfahren und systeme für züchtung und ernte von zellen in einem hohlfaser-bioreaktorsystem mit steuerungsbedingungen |
US8969315B2 (en) | 2010-12-31 | 2015-03-03 | Anthrogenesis Corporation | Enhancement of placental stem cell potency using modulatory RNA molecules |
EP3443968A1 (de) | 2011-06-01 | 2019-02-20 | Celularity, Inc. | Schmerzbehandlung mithilfe von stammzellen aus der plazenta |
US9925221B2 (en) | 2011-09-09 | 2018-03-27 | Celularity, Inc. | Treatment of amyotrophic lateral sclerosis using placental stem cells |
EP2773747B1 (de) * | 2011-11-04 | 2019-01-09 | The Texas A & M University System | Tsg-6 protein zur verwendung bei der vorbeugung und behandlung der abstossung einer hornhauttransplantation |
US9763983B2 (en) | 2013-02-05 | 2017-09-19 | Anthrogenesis Corporation | Natural killer cells from placenta |
WO2014130518A1 (en) | 2013-02-19 | 2014-08-28 | Children's Medical Center Corporation | Abcb5(+) stem cells for treating ocular disease |
ES2827250T3 (es) | 2013-04-12 | 2021-05-20 | Houston Methodist Hospital | Mejora de órganos para trasplante |
CN105517587B (zh) | 2013-05-10 | 2019-02-19 | 儿童医学中心公司 | 伤口愈合与组织工程 |
US20160089421A1 (en) * | 2013-05-22 | 2016-03-31 | National Center Of Neurology And Psychiarty | Stem cells for transplantation and manufacturing method therefor |
KR101723265B1 (ko) | 2013-08-16 | 2017-04-04 | 가톨릭대학교 산학협력단 | mTOR/STAT3 신호억제제 처리된 면역조절능을 갖는 간엽줄기세포 및 이를 포함하는 면역질환의 예방 또는 치료용 세포치료제 조성물 |
WO2015023147A1 (ko) * | 2013-08-16 | 2015-02-19 | 가톨릭대학교 산학협력단 | mTOR/STAT3 신호억제제 처리된 면역조절능을 갖는 간엽 줄기세포 및 이를 포함하는 면역질환의 예방 또는 치료용 세포치료제 조성물 |
US9617506B2 (en) | 2013-11-16 | 2017-04-11 | Terumo Bct, Inc. | Expanding cells in a bioreactor |
EP3613841B1 (de) | 2014-03-25 | 2022-04-20 | Terumo BCT, Inc. | Passives ersetzen von medien |
CN106715676A (zh) | 2014-09-26 | 2017-05-24 | 泰尔茂比司特公司 | 按计划供养 |
RU2644650C2 (ru) | 2014-12-01 | 2018-02-13 | Общество с ограниченной ответственностью "Т-Хелпер Клеточные Технологии" | Материал стволовых клеток и способ его получения |
WO2016109824A1 (en) * | 2014-12-31 | 2016-07-07 | Applied Biologics, Llc | Reconstituted amniotic membrane-amniotic fluid combination tissue graft with standardized stem cell component |
US10857181B2 (en) * | 2015-04-21 | 2020-12-08 | Enlivex Therapeutics Ltd | Therapeutic pooled blood apoptotic cell preparations and uses thereof |
WO2017004592A1 (en) | 2015-07-02 | 2017-01-05 | Terumo Bct, Inc. | Cell growth with mechanical stimuli |
US11389141B2 (en) | 2016-02-01 | 2022-07-19 | RegenMed Systems, Inc. | Cannula for tissue disruption |
GB201604304D0 (en) | 2016-03-14 | 2016-04-27 | Tigenix S A U | Adipose tissue-derived stromal stem cells for use in treating refractory complex perianal fistulas in crohn's disease |
CN109415696A (zh) | 2016-05-25 | 2019-03-01 | 泰尔茂比司特公司 | 细胞扩增 |
RU2708329C2 (ru) | 2016-05-31 | 2019-12-05 | Общество с ограниченной ответственностью "Т-Хелпер Клеточные Технологии" | Материал стволовых клеток, композиции и способы применения |
US11104874B2 (en) | 2016-06-07 | 2021-08-31 | Terumo Bct, Inc. | Coating a bioreactor |
US11685883B2 (en) | 2016-06-07 | 2023-06-27 | Terumo Bct, Inc. | Methods and systems for coating a cell growth surface |
JP7393945B2 (ja) | 2017-03-31 | 2023-12-07 | テルモ ビーシーティー、インコーポレーテッド | 細胞増殖 |
US11624046B2 (en) | 2017-03-31 | 2023-04-11 | Terumo Bct, Inc. | Cell expansion |
CN107454845A (zh) * | 2017-06-13 | 2017-12-08 | 广州赛莱拉干细胞科技股份有限公司 | 一种防治糖尿病足的干细胞组合物及其应用、干细胞制剂 |
US12043823B2 (en) | 2021-03-23 | 2024-07-23 | Terumo Bct, Inc. | Cell capture and expansion |
PT118103A (pt) | 2022-07-13 | 2024-01-15 | Univ Aveiro | Biomaterial para imunomodulação, processo de produção e suas aplicações |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5486359A (en) | 1990-11-16 | 1996-01-23 | Osiris Therapeutics, Inc. | Human mesenchymal stem cells |
US5733542A (en) * | 1990-11-16 | 1998-03-31 | Haynesworth; Stephen E. | Enhancing bone marrow engraftment using MSCS |
US5591625A (en) | 1993-11-24 | 1997-01-07 | Case Western Reserve University | Transduced mesenchymal stem cells |
WO1999051275A2 (en) * | 1998-04-03 | 1999-10-14 | Osiris Therapeutics, Inc. | Mesenchymal stem cells as immunosuppressants |
US6685936B2 (en) * | 1999-10-12 | 2004-02-03 | Osiris Therapeutics, Inc. | Suppressor cells induced by culture with mesenchymal stem cells for treatment of immune responses in transplantation |
CA2490682A1 (en) | 2004-12-16 | 2006-06-16 | Ibm Canada Limited - Ibm Canada Limitee | Method and system for advanced downloadings of urls for web navigation |
TW200819387A (en) | 2006-10-19 | 2008-05-01 | Univ Yuan Ze | Micro-reacting device having a micro-channel flow-guiding block |
-
1999
- 1999-10-26 US US09/427,333 patent/US6368636B1/en not_active Expired - Lifetime
-
2000
- 2000-10-26 AU AU12445/01A patent/AU782064B2/en not_active Expired
- 2000-10-26 CA CA2387542A patent/CA2387542C/en not_active Expired - Lifetime
- 2000-10-26 EP EP10010855A patent/EP2269616A3/de not_active Withdrawn
- 2000-10-26 DE DE60045034T patent/DE60045034D1/de not_active Expired - Lifetime
- 2000-10-26 PT PT00974007T patent/PT1223956E/pt unknown
- 2000-10-26 WO PCT/US2000/029815 patent/WO2001032189A1/en active IP Right Grant
- 2000-10-26 EP EP00974007A patent/EP1223956B1/de not_active Expired - Lifetime
- 2000-10-26 JP JP2001534394A patent/JP2004506598A/ja active Pending
- 2000-10-26 ES ES00974007T patent/ES2351203T3/es not_active Expired - Lifetime
- 2000-10-26 AT AT00974007T patent/ATE482712T1/de not_active IP Right Cessation
-
2001
- 2001-11-13 US US10/067,121 patent/US6875430B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CA2387542A1 (en) | 2001-05-10 |
EP2269616A2 (de) | 2011-01-05 |
WO2001032189A9 (en) | 2002-07-04 |
US6368636B1 (en) | 2002-04-09 |
CA2387542C (en) | 2012-01-24 |
EP2269616A3 (de) | 2012-06-27 |
AU1244501A (en) | 2001-05-14 |
US6875430B2 (en) | 2005-04-05 |
US20020085996A1 (en) | 2002-07-04 |
EP1223956A1 (de) | 2002-07-24 |
ES2351203T3 (es) | 2011-02-01 |
JP2004506598A (ja) | 2004-03-04 |
DE60045034D1 (de) | 2010-11-11 |
EP1223956B1 (de) | 2010-09-29 |
WO2001032189A1 (en) | 2001-05-10 |
AU782064B2 (en) | 2005-06-30 |
PT1223956E (pt) | 2010-12-06 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE482712T1 (de) | Überstände von mesenchymstammzellen zur vorbeugung und behandlung von immunantworten in transplantationen | |
ATE319312T1 (de) | Suppressorzellen zur prävention und behandlung von immunantworten bei transplantationen | |
ATE316795T1 (de) | Mesenchymale stammzellen für die prävention und behandlung von immunantworten bei transplantationen | |
ES2180653T3 (es) | Tratamiento de material biologico antes de la implantacion. | |
DK0987998T3 (da) | Decellulering af væv | |
DE69837491D1 (de) | Menschliche mesenchymale stammzellen aus peripherem blut | |
DE69941903D1 (de) | Behandlung von patienten die eine knochenmarktransplantation oder eine transplantation peripherer blutstammzellen erhalten mit anti-cd20 antikörpern | |
DE69525151D1 (de) | Methoden zur krankheitsbehandlung unter verwendung von sertoli-zellen und allotransplantat oder xenotransplantat | |
WO2007070301A3 (en) | Vascular graft sterilization and decellularization | |
DE69829202D1 (de) | Verwendung von mirtazapine zur herstellung eines medikaments zur behandlung von schlafapnoen | |
WO2004011631A3 (en) | Methods and compositions for treating tissue defects using pulsed electromagnetic field stimulus | |
NO20054912D0 (no) | Behandling av aspergillus infeksjoner med tymosin alfa 1 | |
HK1087328A1 (en) | Therapeutic composition for autoimmune conditions | |
DK1150698T3 (da) | Anvendelser af vaskulær endotelvækstfaktor i behandlingen af erektil dysfunktion | |
ATE297217T1 (de) | Zusammensetzung zur vorbeugung und behandlung von transplantatabstossung | |
BR0107544A (pt) | Composição de promoção de secreção de bile | |
DE60033840D1 (de) | Antisense-zusammensetzungen und verfahren zur behandlung von krebs | |
ATE382378T1 (de) | Implantatmaterial | |
ES2180345T3 (es) | Nuevo procedimiento para la crio-conservacion de plantas. | |
TW200621986A (en) | Liver stromal cells for prevention and treatment of immune responses in transplantation | |
ATE306278T1 (de) | Behandlung von knochenleiden mit adrenomedullin | |
DE50004024D1 (de) | Verwendung von treosulfan zur konditionierung von patienten vor knochenmarktransplantation oder blutstammzelltransplantation | |
UA6151U (en) | Method for treating experimental burns | |
UA69988A (en) | Method for treating complicated choledocholithiasis | |
ATE419843T1 (de) | Methode zur in vitro reduzierung von durch freie radikale induzierte schäden |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |