LU91104I2 - Derive o-alkyle de la rapamycine et son utilisation, en pariculier comme immunosuppresseur. - Google Patents

Derive o-alkyle de la rapamycine et son utilisation, en pariculier comme immunosuppresseur.

Info

Publication number
LU91104I2
LU91104I2 LU91104C LU91104C LU91104I2 LU 91104 I2 LU91104 I2 LU 91104I2 LU 91104 C LU91104 C LU 91104C LU 91104 C LU91104 C LU 91104C LU 91104 I2 LU91104 I2 LU 91104I2
Authority
LU
Luxembourg
Prior art keywords
alkyl
rapamycin
immunosuppressant
allyl
alkyl derivative
Prior art date
Application number
LU91104C
Other languages
English (en)
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10723188&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LU91104(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of LU91104I2 publication Critical patent/LU91104I2/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Transplantation (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Dental Preparations (AREA)
LU91104C 1992-10-09 2004-09-29 Derive o-alkyle de la rapamycine et son utilisation, en pariculier comme immunosuppresseur. LU91104I2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929221220A GB9221220D0 (en) 1992-10-09 1992-10-09 Organic componds
PCT/EP1993/002604 WO1994009010A1 (fr) 1992-10-09 1993-09-24 Derives o-alkyles de la rapamycine et leur utilisation, en particulier comme immunosuppresseurs

Publications (1)

Publication Number Publication Date
LU91104I2 true LU91104I2 (fr) 2004-11-29

Family

ID=10723188

Family Applications (1)

Application Number Title Priority Date Filing Date
LU91104C LU91104I2 (fr) 1992-10-09 2004-09-29 Derive o-alkyle de la rapamycine et son utilisation, en pariculier comme immunosuppresseur.

Country Status (28)

Country Link
US (2) US5665772A (fr)
EP (3) EP0663916B1 (fr)
JP (2) JP3117462B2 (fr)
KR (2) KR100308598B1 (fr)
AT (2) ATE272063T1 (fr)
AU (1) AU676198B2 (fr)
BR (1) BR1100353A (fr)
CA (2) CA2145383C (fr)
CY (2) CY2125B1 (fr)
CZ (1) CZ283333B6 (fr)
DE (3) DE69322282T2 (fr)
DK (2) DK0867438T3 (fr)
ES (2) ES2124793T3 (fr)
FI (2) FI109540B (fr)
FR (1) FR04C0012I2 (fr)
GB (1) GB9221220D0 (fr)
GE (1) GEP20002331B (fr)
HU (1) HU224074B1 (fr)
LU (1) LU91104I2 (fr)
NL (1) NL300154I2 (fr)
NO (3) NO307053B1 (fr)
NZ (1) NZ256026A (fr)
PL (1) PL176174B1 (fr)
PT (1) PT867438E (fr)
RO (1) RO114451B1 (fr)
RU (1) RU2143434C1 (fr)
SK (2) SK286054B6 (fr)
WO (1) WO1994009010A1 (fr)

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* Cited by examiner, † Cited by third party
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NO2017067I1 (no) 2017-12-07
BR1100353A (pt) 2000-06-06
JPH08502266A (ja) 1996-03-12
NL300154I2 (nl) 2004-10-01
CA2145383C (fr) 2004-11-16
NO307053B1 (no) 2000-01-31
GEP20002331B (en) 2000-12-25
CA2145383A1 (fr) 1994-04-28
CZ283333B6 (cs) 1998-02-18
PL308268A1 (en) 1995-07-24
EP0663916B1 (fr) 1998-11-25
AU676198B2 (en) 1997-03-06
US6440990B1 (en) 2002-08-27

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