FI951678A - O- alkyloituja rapamysiinijohdannaisia ja niiden käyttö, erityisesti immunosupressoivina aineina - Google Patents

O- alkyloituja rapamysiinijohdannaisia ja niiden käyttö, erityisesti immunosupressoivina aineina Download PDF

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Publication number
FI951678A
FI951678A FI951678A FI951678A FI951678A FI 951678 A FI951678 A FI 951678A FI 951678 A FI951678 A FI 951678A FI 951678 A FI951678 A FI 951678A FI 951678 A FI951678 A FI 951678A
Authority
FI
Finland
Prior art keywords
alkyl
immunosuppressive agents
rapamycin derivatives
allyl
alkylated rapamycin
Prior art date
Application number
FI951678A
Other languages
English (en)
Swedish (sv)
Other versions
FI951678A0 (fi
FI109540B (fi
Inventor
Sylvain Cottens
Richard Sedrani
Original Assignee
Sandoz Ltd
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10723188&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI951678(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sandoz Ltd filed Critical Sandoz Ltd
Publication of FI951678A publication Critical patent/FI951678A/fi
Publication of FI951678A0 publication Critical patent/FI951678A0/fi
Application granted granted Critical
Publication of FI109540B publication Critical patent/FI109540B/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
FI951678A 1992-10-09 1995-04-07 Menetelmä terapeuttisesti käyttökelpoisen 40-0-(2-hydroksietyyli) -rapamysiinin valmistamiseksi FI109540B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB9221220 1992-10-09
GB929221220A GB9221220D0 (en) 1992-10-09 1992-10-09 Organic componds
EP9302604 1993-09-24
PCT/EP1993/002604 WO1994009010A1 (en) 1992-10-09 1993-09-24 O-alkylated rapamycin derivatives and their use, particularly as immunosuppressants

Publications (3)

Publication Number Publication Date
FI951678A true FI951678A (fi) 1995-04-07
FI951678A0 FI951678A0 (fi) 1995-04-07
FI109540B FI109540B (fi) 2002-08-30

Family

ID=10723188

Family Applications (2)

Application Number Title Priority Date Filing Date
FI951678A FI109540B (fi) 1992-10-09 1995-04-07 Menetelmä terapeuttisesti käyttökelpoisen 40-0-(2-hydroksietyyli) -rapamysiinin valmistamiseksi
FI20001943A FI20001943A (fi) 1992-10-09 2000-09-04 O-alkyloituja rapamysiinijohdannaisia ja niiden käyttö, erityisesti immunosupressoivina aineina

Family Applications After (1)

Application Number Title Priority Date Filing Date
FI20001943A FI20001943A (fi) 1992-10-09 2000-09-04 O-alkyloituja rapamysiinijohdannaisia ja niiden käyttö, erityisesti immunosupressoivina aineina

Country Status (28)

Country Link
US (2) US5665772A (fi)
EP (3) EP0663916B1 (fi)
JP (2) JP3117462B2 (fi)
KR (2) KR100308598B1 (fi)
AT (2) ATE173736T1 (fi)
AU (1) AU676198B2 (fi)
BR (1) BR1100353A (fi)
CA (2) CA2145383C (fi)
CY (2) CY2125B1 (fi)
CZ (1) CZ283333B6 (fi)
DE (3) DE122004000033I2 (fi)
DK (2) DK0867438T3 (fi)
ES (2) ES2124793T3 (fi)
FI (2) FI109540B (fi)
FR (1) FR04C0012I2 (fi)
GB (1) GB9221220D0 (fi)
GE (1) GEP20002331B (fi)
HU (1) HU224074B1 (fi)
LU (1) LU91104I2 (fi)
NL (1) NL300154I2 (fi)
NO (3) NO307053B1 (fi)
NZ (1) NZ256026A (fi)
PL (1) PL176174B1 (fi)
PT (1) PT867438E (fi)
RO (1) RO114451B1 (fi)
RU (1) RU2143434C1 (fi)
SK (2) SK285256B6 (fi)
WO (1) WO1994009010A1 (fi)

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