EA201290876A1 - Композиции индуцированных дендритных клеток и их использование - Google Patents
Композиции индуцированных дендритных клеток и их использованиеInfo
- Publication number
- EA201290876A1 EA201290876A1 EA201290876A EA201290876A EA201290876A1 EA 201290876 A1 EA201290876 A1 EA 201290876A1 EA 201290876 A EA201290876 A EA 201290876A EA 201290876 A EA201290876 A EA 201290876A EA 201290876 A1 EA201290876 A1 EA 201290876A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- dendritic cells
- compositions
- induced dendritic
- production
- methods
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 210000004443 dendritic cell Anatomy 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 230000003614 tolerogenic effect Effects 0.000 abstract 1
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- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0639—Dendritic cells, e.g. Langherhans cells in the epidermis
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- A61K35/15—Cells of the myeloid line, e.g. granulocytes, basophils, eosinophils, neutrophils, leucocytes, monocytes, macrophages or mast cells; Myeloid precursor cells; Antigen-presenting cells, e.g. dendritic cells
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Abstract
Изобретение представляет, например, композиции, содержащие индуцированные толерогенные дендритные клетки, которые способны подавлять иммунный ответ, опосредованный антигенспецифичными Т-клетками, и способы их производства и использования. Кроме того, изобретение представляет композиции, содержащие индуцированные иммуногенные дендритные клетки, и способы их производства и использования.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US31102310P | 2010-03-05 | 2010-03-05 | |
PCT/US2011/027445 WO2011109833A2 (en) | 2010-03-05 | 2011-03-07 | Induced dendritic cell compositions and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
EA201290876A1 true EA201290876A1 (ru) | 2013-03-29 |
Family
ID=44064962
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA201290876A EA201290876A1 (ru) | 2010-03-05 | 2011-03-07 | Композиции индуцированных дендритных клеток и их использование |
Country Status (6)
Country | Link |
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US (1) | US20130195919A1 (ru) |
EP (1) | EP2542670A2 (ru) |
JP (1) | JP2013521002A (ru) |
CA (1) | CA2792258A1 (ru) |
EA (1) | EA201290876A1 (ru) |
WO (1) | WO2011109833A2 (ru) |
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CN103517716A (zh) | 2011-04-29 | 2014-01-15 | 西莱克塔生物科技公司 | 用于诱导调节性b细胞的致耐受性合成纳米载体 |
WO2013036297A1 (en) * | 2011-09-06 | 2013-03-14 | Selecta Biosciences, Inc. | Therapeutic protein-specific induced tolerogenic dendritic cells and methods of use |
JP6194003B2 (ja) | 2012-10-09 | 2017-09-06 | ザ プロクター アンド ギャンブル カンパニー | 有益剤及びこれを含む組成物の特定又は評価方法 |
CN104703585A (zh) | 2012-10-09 | 2015-06-10 | 宝洁公司 | 鉴定协同化妆品组合的方法 |
BR112015027297B1 (pt) | 2013-05-03 | 2023-01-10 | Selecta Biosciences, Inc | Uso de nanocarreadores sintéticos que são fixados a imunossupressores e de uma composição compreendendo os referidos nanocarreadores |
US20160230174A1 (en) * | 2013-09-26 | 2016-08-11 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Tolerogenic dendritic cells to treat inflammatory bowel disease |
US9724365B2 (en) | 2013-11-18 | 2017-08-08 | University of Pittsburgh—of the Commonwealth System of Higher Education | Microsphere-based delivery and ex vivo manipulation of dendritic cells for autoimmune therapies |
WO2016011347A1 (en) * | 2014-07-17 | 2016-01-21 | The Trustees Of The University Of Pennsylvania | Multi-dose injection ready dendritic cell vaccines and combination therapy for cancer |
KR101518972B1 (ko) * | 2014-08-01 | 2015-05-18 | 제이더블유크레아젠 주식회사 | 수지상세포의 제조방법, 이에 의해 제조된 수지상세포 및 그 용도 |
CA2957808A1 (en) | 2014-09-07 | 2016-03-10 | Selecta Biosciences, Inc. | Methods and compositions for attenuating exon skipping anti-viral transfer vector immune responses |
EP3130678B1 (en) * | 2015-08-11 | 2019-02-20 | Universitätsmedizin der Johannes Gutenberg-Universität Mainz | In-vitro methods for the detection of treg resistance and autoimmune diseases |
US20170199176A1 (en) * | 2016-01-11 | 2017-07-13 | Nodality, Inc. | T cell populations in diagnosis, prognosis, prediction, and monitoring |
WO2018024893A1 (en) * | 2016-08-05 | 2018-02-08 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Invariant foxp3+ regulatory t cells and therapeutic uses thereof |
WO2018024894A1 (en) * | 2016-08-05 | 2018-02-08 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Ex vivo generation of mhcii restricted cd4+foxp3+ regulatory t cells and therapeutic uses thereof |
JP6987338B2 (ja) * | 2016-08-05 | 2021-12-22 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | MHCII拘束性CD4+FOXP3+制御性T細胞のex vivo生成及びその治療的使用 |
US11198851B2 (en) | 2016-10-28 | 2021-12-14 | Inserm (Institut National De La Sante Et De La Rechere Medicale) | Ex vivo generation of γδ Foxp3+ regulatory T cells and therapeutic uses thereof |
KR101946572B1 (ko) * | 2017-01-31 | 2019-02-11 | 주식회사 큐라티스 | 면역 관용성 플라즈마사이토이드 수지상 세포 및 그 제조방법 |
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EP3698797A1 (en) * | 2017-10-16 | 2020-08-26 | Tsinghua University | Mevalonic acid pathway inhibitor and pharmaceutical composition thereof |
WO2021181591A1 (ja) * | 2020-03-12 | 2021-09-16 | コニカミノルタ株式会社 | 細胞の分化状態を評価する方法、ゼラチンナノ粒子およびゼラチンナノ粒子のセット |
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-
2011
- 2011-03-07 EA EA201290876A patent/EA201290876A1/ru unknown
- 2011-03-07 CA CA2792258A patent/CA2792258A1/en not_active Abandoned
- 2011-03-07 JP JP2012556287A patent/JP2013521002A/ja active Pending
- 2011-03-07 US US13/582,897 patent/US20130195919A1/en not_active Abandoned
- 2011-03-07 EP EP11707990A patent/EP2542670A2/en not_active Withdrawn
- 2011-03-07 WO PCT/US2011/027445 patent/WO2011109833A2/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
JP2013521002A (ja) | 2013-06-10 |
WO2011109833A2 (en) | 2011-09-09 |
CA2792258A1 (en) | 2011-09-09 |
WO2011109833A3 (en) | 2011-11-24 |
EP2542670A2 (en) | 2013-01-09 |
US20130195919A1 (en) | 2013-08-01 |
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