EA201391597A1 - Толерогенные синтетические наноносители, уменьшающие иммунный ответ на терапевтические белки - Google Patents
Толерогенные синтетические наноносители, уменьшающие иммунный ответ на терапевтические белкиInfo
- Publication number
- EA201391597A1 EA201391597A1 EA201391597A EA201391597A EA201391597A1 EA 201391597 A1 EA201391597 A1 EA 201391597A1 EA 201391597 A EA201391597 A EA 201391597A EA 201391597 A EA201391597 A EA 201391597A EA 201391597 A1 EA201391597 A1 EA 201391597A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- therapeutic proteins
- immune response
- synthetic nano
- decreasing immune
- tolerogenic synthetic
- Prior art date
Links
- 102000004169 proteins and genes Human genes 0.000 title abstract 3
- 108090000623 proteins and genes Proteins 0.000 title abstract 3
- 230000001225 therapeutic effect Effects 0.000 title abstract 3
- 230000028993 immune response Effects 0.000 title abstract 2
- 230000003614 tolerogenic effect Effects 0.000 title abstract 2
- 230000003247 decreasing effect Effects 0.000 title 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 229960003444 immunosuppressant agent Drugs 0.000 abstract 1
- 239000003018 immunosuppressive agent Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000002539 nanocarrier Substances 0.000 abstract 1
Classifications
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Abstract
Раскрыты композиции синтетических наноносителей и связанные с ними способы, включающие терапевтические белкипрезентируемые АРС антигены и иммунодепрессанты, которые обеспечивают толерогенные иммунные ответы, специфические в отношении терапевтических белков.
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US201161480946P | 2011-04-29 | 2011-04-29 | |
US201161513514P | 2011-07-29 | 2011-07-29 | |
US201161531147P | 2011-09-06 | 2011-09-06 | |
US201161531168P | 2011-09-06 | 2011-09-06 | |
US201161531180P | 2011-09-06 | 2011-09-06 | |
US201161531194P | 2011-09-06 | 2011-09-06 | |
US201161531153P | 2011-09-06 | 2011-09-06 | |
US201161531215P | 2011-09-06 | 2011-09-06 | |
US201161531175P | 2011-09-06 | 2011-09-06 | |
US201161531209P | 2011-09-06 | 2011-09-06 | |
US201161531204P | 2011-09-06 | 2011-09-06 | |
US201161531164P | 2011-09-06 | 2011-09-06 | |
PCT/US2012/035366 WO2012149255A2 (en) | 2011-04-29 | 2012-04-27 | Tolerogenic synthetic nanocarriers to reduce immune responses to therapeutic proteins |
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EA027103B1 EA027103B1 (ru) | 2017-06-30 |
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EA201391601A EA027410B1 (ru) | 2011-04-29 | 2012-04-27 | Наноносители, вызывающие иммунную толерантность, для снижения ответной реакции цитотоксических t-лимфоцитов |
EA201790045A EA201790045A1 (ru) | 2011-04-29 | 2012-04-27 | Наноносители, вырабатывающие имунную толерантность, для антиген-специфического удаления т-эффекторных клеток |
EA201790109A EA201790109A1 (ru) | 2011-04-29 | 2012-04-27 | Толерогенные синтетические наноносители, уменьшающие иммунный ответ на терапевтические белки |
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US6993506B2 (en) | 2000-12-05 | 2006-01-31 | Jgr Acquisition, Inc. | Method and device utilizing polymorphic data in e-commerce |
US20070084897A1 (en) | 2003-05-20 | 2007-04-19 | Shelton Frederick E Iv | Articulating surgical stapling instrument incorporating a two-piece e-beam firing mechanism |
US9060770B2 (en) | 2003-05-20 | 2015-06-23 | Ethicon Endo-Surgery, Inc. | Robotically-driven surgical instrument with E-beam driver |
US11896225B2 (en) | 2004-07-28 | 2024-02-13 | Cilag Gmbh International | Staple cartridge comprising a pan |
US8215531B2 (en) | 2004-07-28 | 2012-07-10 | Ethicon Endo-Surgery, Inc. | Surgical stapling instrument having a medical substance dispenser |
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