EA201391602A1 - Контролируемое высвобождение иммунодепрессантов из синтетических наноносителей - Google Patents

Контролируемое высвобождение иммунодепрессантов из синтетических наноносителей

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Publication number
EA201391602A1
EA201391602A1 EA201391602A EA201391602A EA201391602A1 EA 201391602 A1 EA201391602 A1 EA 201391602A1 EA 201391602 A EA201391602 A EA 201391602A EA 201391602 A EA201391602 A EA 201391602A EA 201391602 A1 EA201391602 A1 EA 201391602A1
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EA
Eurasian Patent Office
Prior art keywords
immunodpressants
synthetic nano
controlled emission
media
nano media
Prior art date
Application number
EA201391602A
Other languages
English (en)
Inventor
Дэвид Х. Алтройтер
Аарон П. Грисет
Роберто А. Мальдонадо
Original Assignee
Селекта Байосайенсиз, Инк.
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Publication date
Application filed by Селекта Байосайенсиз, Инк. filed Critical Селекта Байосайенсиз, Инк.
Publication of EA201391602A1 publication Critical patent/EA201391602A1/ru

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    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
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Abstract

Раскрыты композиции синтетических наноносителей, которые обеспечивают контролируемое высвобождение иммунодепрессантов, а также связанные способы. В некоторых вариантах осуществления композиции синтетических наноносителей могут также включать антиген.
EA201391602A 2011-04-29 2012-04-27 Контролируемое высвобождение иммунодепрессантов из синтетических наноносителей EA201391602A1 (ru)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US201161480946P 2011-04-29 2011-04-29
US201161513514P 2011-07-29 2011-07-29
US201161531153P 2011-09-06 2011-09-06
US201161531180P 2011-09-06 2011-09-06
US201161531168P 2011-09-06 2011-09-06
US201161531147P 2011-09-06 2011-09-06
US201161531204P 2011-09-06 2011-09-06
US201161531209P 2011-09-06 2011-09-06
US201161531215P 2011-09-06 2011-09-06
US201161531175P 2011-09-06 2011-09-06
US201161531194P 2011-09-06 2011-09-06
US201161531164P 2011-09-06 2011-09-06
PCT/US2012/035581 WO2012149411A1 (en) 2011-04-29 2012-04-27 Controlled release of immunosuppressants from synthetic nanocarriers

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EA201391602A1 true EA201391602A1 (ru) 2014-04-30

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EA201391601A EA027410B1 (ru) 2011-04-29 2012-04-27 Наноносители, вызывающие иммунную толерантность, для снижения ответной реакции цитотоксических t-лимфоцитов
EA201391611A EA201391611A1 (ru) 2011-04-29 2012-04-27 Вызывающие иммунную толерантность синтетические наноносители для терапевтического лечения аллергии
EA201791679A EA201791679A1 (ru) 2011-04-29 2012-04-27 Толерогенные синтетические наноносители
EA201790044A EA201790044A1 (ru) 2011-04-29 2012-04-27 Толерогенные синтетические наноносители для индукции регуляторных в-клеток
EA201391610A EA027380B1 (ru) 2011-04-29 2012-04-27 Наноносители, вырабатывающие иммунную толерантность, для вырабатывания cd8регуляторных т-клеток
EA201790109A EA201790109A1 (ru) 2011-04-29 2012-04-27 Толерогенные синтетические наноносители, уменьшающие иммунный ответ на терапевтические белки
EA201391602A EA201391602A1 (ru) 2011-04-29 2012-04-27 Контролируемое высвобождение иммунодепрессантов из синтетических наноносителей
EA201391600A EA026880B1 (ru) 2011-04-29 2012-04-27 Наноносители, вызывающие иммунную толерантность, для снижения ответной реакции антител
EA201790043A EA201790043A1 (ru) 2011-04-29 2012-04-27 Наноносители, вырабатывающие иммунную толерантность, для вырабатывания cd8+ регуляторных т-клеток
EA201391599A EA028807B1 (ru) 2011-04-29 2012-04-27 Композиции, содержащие толерогенные синтетические наноносители, и их применение
EA201391608A EA027259B1 (ru) 2011-04-29 2012-04-27 Наноносители, вырабатывающие иммунную толерантность, для антиген-специфического удаления т-эффекторных клеток
EA201790030A EA201790030A1 (ru) 2011-04-29 2012-04-27 Наноносители, вызывающие иммунную толерантность, для снижения ответной реакции цитотоксических т-лимфоцитов
EA201391609A EA027379B1 (ru) 2011-04-29 2012-04-27 Толерогенные синтетические наноносители для индукции регуляторных b-клеток
EA201790045A EA201790045A1 (ru) 2011-04-29 2012-04-27 Наноносители, вырабатывающие имунную толерантность, для антиген-специфического удаления т-эффекторных клеток
EA201391597A EA027103B1 (ru) 2011-04-29 2012-04-27 Толерогенные синтетические наноносители, уменьшающие иммунный ответ на терапевтические белки
EA201692374A EA201692374A3 (ru) 2011-04-29 2012-04-27 Наноносители, вызывающие иммунную толерантность, для снижения ответной реакции антител

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EA201391601A EA027410B1 (ru) 2011-04-29 2012-04-27 Наноносители, вызывающие иммунную толерантность, для снижения ответной реакции цитотоксических t-лимфоцитов
EA201391611A EA201391611A1 (ru) 2011-04-29 2012-04-27 Вызывающие иммунную толерантность синтетические наноносители для терапевтического лечения аллергии
EA201791679A EA201791679A1 (ru) 2011-04-29 2012-04-27 Толерогенные синтетические наноносители
EA201790044A EA201790044A1 (ru) 2011-04-29 2012-04-27 Толерогенные синтетические наноносители для индукции регуляторных в-клеток
EA201391610A EA027380B1 (ru) 2011-04-29 2012-04-27 Наноносители, вырабатывающие иммунную толерантность, для вырабатывания cd8регуляторных т-клеток
EA201790109A EA201790109A1 (ru) 2011-04-29 2012-04-27 Толерогенные синтетические наноносители, уменьшающие иммунный ответ на терапевтические белки

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EA201391600A EA026880B1 (ru) 2011-04-29 2012-04-27 Наноносители, вызывающие иммунную толерантность, для снижения ответной реакции антител
EA201790043A EA201790043A1 (ru) 2011-04-29 2012-04-27 Наноносители, вырабатывающие иммунную толерантность, для вырабатывания cd8+ регуляторных т-клеток
EA201391599A EA028807B1 (ru) 2011-04-29 2012-04-27 Композиции, содержащие толерогенные синтетические наноносители, и их применение
EA201391608A EA027259B1 (ru) 2011-04-29 2012-04-27 Наноносители, вырабатывающие иммунную толерантность, для антиген-специфического удаления т-эффекторных клеток
EA201790030A EA201790030A1 (ru) 2011-04-29 2012-04-27 Наноносители, вызывающие иммунную толерантность, для снижения ответной реакции цитотоксических т-лимфоцитов
EA201391609A EA027379B1 (ru) 2011-04-29 2012-04-27 Толерогенные синтетические наноносители для индукции регуляторных b-клеток
EA201790045A EA201790045A1 (ru) 2011-04-29 2012-04-27 Наноносители, вырабатывающие имунную толерантность, для антиген-специфического удаления т-эффекторных клеток
EA201391597A EA027103B1 (ru) 2011-04-29 2012-04-27 Толерогенные синтетические наноносители, уменьшающие иммунный ответ на терапевтические белки
EA201692374A EA201692374A3 (ru) 2011-04-29 2012-04-27 Наноносители, вызывающие иммунную толерантность, для снижения ответной реакции антител

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US11235057B2 (en) 2022-02-01
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