EA201992133A1 - Производные пиперидино-пиримидина для лечения вирусных инфекций - Google Patents

Производные пиперидино-пиримидина для лечения вирусных инфекций

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Publication number
EA201992133A1
EA201992133A1 EA201992133A EA201992133A EA201992133A1 EA 201992133 A1 EA201992133 A1 EA 201992133A1 EA 201992133 A EA201992133 A EA 201992133A EA 201992133 A EA201992133 A EA 201992133A EA 201992133 A1 EA201992133 A1 EA 201992133A1
Authority
EA
Eurasian Patent Office
Prior art keywords
piperidino
treatment
viral infections
pyrimidine derivatives
pyrimidine
Prior art date
Application number
EA201992133A
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English (en)
Other versions
EA039373B1 (ru
Inventor
Дэвид Крейг Мак Гоуен
Пьер Жан-Мари Бернар Рабуассон
Тим Хьюго Мария Йонкерс
Мурад Дауби Хамличи
Original Assignee
Янссен Сайенсиз Айрлэнд Юси
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Application filed by Янссен Сайенсиз Айрлэнд Юси filed Critical Янссен Сайенсиз Айрлэнд Юси
Publication of EA201992133A1 publication Critical patent/EA201992133A1/ru
Publication of EA039373B1 publication Critical patent/EA039373B1/ru

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Abstract

Настоящее изобретение относится к производным пиперидино-пиримидина, способам их получения, фармацевтическим композициям и их применению при лечении вирусных инфекций.
EA201992133A 2012-02-08 2013-02-07 Производные пиперидино-пиримидина для лечения вирусных инфекций EA039373B1 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP12154474 2012-02-08

Publications (2)

Publication Number Publication Date
EA201992133A1 true EA201992133A1 (ru) 2020-02-05
EA039373B1 EA039373B1 (ru) 2022-01-19

Family

ID=47678822

Family Applications (2)

Application Number Title Priority Date Filing Date
EA201992133A EA039373B1 (ru) 2012-02-08 2013-02-07 Производные пиперидино-пиримидина для лечения вирусных инфекций
EA201491486A EA033907B1 (ru) 2012-02-08 2013-02-07 Производные пиперидино-пиримидина, фармацевтическая композиция и их применение

Family Applications After (1)

Application Number Title Priority Date Filing Date
EA201491486A EA033907B1 (ru) 2012-02-08 2013-02-07 Производные пиперидино-пиримидина, фармацевтическая композиция и их применение

Country Status (22)

Country Link
US (2) US9133192B2 (ru)
EP (1) EP2812331B1 (ru)
JP (1) JP6283320B2 (ru)
KR (1) KR102064807B1 (ru)
CN (1) CN104245695B (ru)
AU (1) AU2013218072B2 (ru)
CA (1) CA2862823C (ru)
CL (1) CL2014002093A1 (ru)
DK (1) DK2812331T3 (ru)
EA (2) EA039373B1 (ru)
ES (1) ES2716811T3 (ru)
HK (1) HK1201254A1 (ru)
IL (1) IL233499B (ru)
IN (1) IN2014MN01736A (ru)
MX (1) MX357296B (ru)
MY (1) MY169159A (ru)
NZ (1) NZ627036A (ru)
PH (1) PH12014501738B1 (ru)
SG (1) SG11201404743TA (ru)
UA (1) UA112668C2 (ru)
WO (1) WO2013117615A1 (ru)
ZA (1) ZA201405820B (ru)

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