ATE81467T1 - Immunosuppression bei der auf immunotoxin basierten behandlung von menschen. - Google Patents

Immunosuppression bei der auf immunotoxin basierten behandlung von menschen.

Info

Publication number
ATE81467T1
ATE81467T1 AT88902708T AT88902708T ATE81467T1 AT E81467 T1 ATE81467 T1 AT E81467T1 AT 88902708 T AT88902708 T AT 88902708T AT 88902708 T AT88902708 T AT 88902708T AT E81467 T1 ATE81467 T1 AT E81467T1
Authority
AT
Austria
Prior art keywords
immunotoxin
immunosuppression
humans
based treatment
cyclophosphamide
Prior art date
Application number
AT88902708T
Other languages
English (en)
Inventor
Ronald P Mischak
Patrick J Scannon
Lynn E Spitler
W Scott Harkonen
Langdon Miller
Original Assignee
Xoma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xoma Corp filed Critical Xoma Corp
Application granted granted Critical
Publication of ATE81467T1 publication Critical patent/ATE81467T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pyrane Compounds (AREA)
AT88902708T 1987-02-24 1988-02-23 Immunosuppression bei der auf immunotoxin basierten behandlung von menschen. ATE81467T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1832487A 1987-02-24 1987-02-24
EP88902708A EP0303681B1 (de) 1987-02-24 1988-02-23 Immunosuppression bei der auf immunotoxin basierten behandlung von menschen
PCT/US1988/000576 WO1988006451A1 (en) 1987-02-24 1988-02-23 Immunosuppression in immunotoxin based human therapy

Publications (1)

Publication Number Publication Date
ATE81467T1 true ATE81467T1 (de) 1992-10-15

Family

ID=21787358

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88902708T ATE81467T1 (de) 1987-02-24 1988-02-23 Immunosuppression bei der auf immunotoxin basierten behandlung von menschen.

Country Status (7)

Country Link
EP (1) EP0303681B1 (de)
JP (1) JPH01502909A (de)
KR (1) KR890700353A (de)
AT (1) ATE81467T1 (de)
AU (1) AU619740B2 (de)
DE (1) DE3875306T2 (de)
WO (1) WO1988006451A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9200417D0 (en) * 1992-01-09 1992-02-26 Bagshawe Kenneth D Cytotoxic drug therapy
AU5369798A (en) * 1996-11-27 1998-06-22 Bachem Bioscience, Inc. Shk toxin compositions and methods of use
US6593362B2 (en) 2001-05-21 2003-07-15 Guilford Pharmaceuticals Inc. Non-peptidic cyclophilin binding compounds and their use
US7833979B2 (en) 2005-04-22 2010-11-16 Amgen Inc. Toxin peptide therapeutic agents
GB0605395D0 (en) * 2006-03-16 2006-04-26 Norwegian Radium Hospital Res Anti-cancer therapy
US7825093B2 (en) 2006-10-25 2010-11-02 Amgen Inc. Methods of using OSK1 peptide analogs
WO2008125903A2 (en) * 2006-12-12 2008-10-23 Chaim Sheba Medical Center Method of inhibiting an undesired immune response
CA2687141C (en) 2007-05-22 2014-04-01 Amgen Inc. Compositions and methods for producing bioactive fusion proteins
CN107261154A (zh) 2011-04-29 2017-10-20 西莱克塔生物科技公司 致耐受性合成纳米载体
AU2014262163A1 (en) 2013-05-03 2015-11-19 Selecta Biosciences, Inc. Delivery of immunosuppressants having a specified pharmacodynamic effective-life and antigen for the inducation of immune tolerance
EP3189138A4 (de) 2014-09-07 2018-04-18 Selecta Biosciences, Inc. Verfahren und zusammensetzungen zur abschwächung der immunantworten auf antivirale geneditierende transfervektoren
CA3055936A1 (en) 2017-03-11 2018-09-20 Selecta Biosciences, Inc. Methods and compositions related to combined treatment with anti-inflammatories and synthetic nanocarriers comprising an immunosuppressant

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2573656B1 (fr) * 1984-11-29 1987-02-27 Sanofi Sa Medicament comportant en tant qu'association au moins une immunotoxine et au moins un polymere contenant du mannose
FR2577135B1 (fr) * 1985-02-13 1989-12-15 Sanofi Sa Immunotoxines a longue duree d'action comportant un constituant glycopeptidique inactivant les ribosomes modifie sur ses motifs polysaccharidiques
FR2584294B1 (fr) * 1985-07-08 1992-02-21 Berdal Pascal Compositions pharmaceutiques a visee cytotrophique
NZ218460A (en) * 1985-11-29 1989-07-27 Univ Melbourne Ricin-antibody conjugate

Also Published As

Publication number Publication date
KR890700353A (ko) 1989-04-24
AU1421488A (en) 1988-09-26
JPH01502909A (ja) 1989-10-05
DE3875306T2 (de) 1993-04-01
DE3875306D1 (de) 1992-11-19
EP0303681B1 (de) 1992-10-14
EP0303681A4 (de) 1989-12-28
AU619740B2 (en) 1992-02-06
EP0303681A1 (de) 1989-02-22
WO1988006451A1 (en) 1988-09-07

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Legal Events

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