DE3875306D1 - Immunosuppression bei der auf immunotoxin basierten behandlung von menschen. - Google Patents

Immunosuppression bei der auf immunotoxin basierten behandlung von menschen.

Info

Publication number
DE3875306D1
DE3875306D1 DE8888902708T DE3875306T DE3875306D1 DE 3875306 D1 DE3875306 D1 DE 3875306D1 DE 8888902708 T DE8888902708 T DE 8888902708T DE 3875306 T DE3875306 T DE 3875306T DE 3875306 D1 DE3875306 D1 DE 3875306D1
Authority
DE
Germany
Prior art keywords
immunotoxin
treatment
immunosuppression
people based
cyclophosphamide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8888902708T
Other languages
English (en)
Other versions
DE3875306T2 (de
Inventor
P Mischak
J Scannon
E Spitler
Scott Harkonen
Langdon Miller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Xoma Corp
Original Assignee
Xoma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xoma Corp filed Critical Xoma Corp
Application granted granted Critical
Publication of DE3875306D1 publication Critical patent/DE3875306D1/de
Publication of DE3875306T2 publication Critical patent/DE3875306T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13Cyclosporins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Mycology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pyrane Compounds (AREA)
DE8888902708T 1987-02-24 1988-02-23 Immunosuppression bei der auf immunotoxin basierten behandlung von menschen. Expired - Fee Related DE3875306T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1832487A 1987-02-24 1987-02-24
PCT/US1988/000576 WO1988006451A1 (en) 1987-02-24 1988-02-23 Immunosuppression in immunotoxin based human therapy

Publications (2)

Publication Number Publication Date
DE3875306D1 true DE3875306D1 (de) 1992-11-19
DE3875306T2 DE3875306T2 (de) 1993-04-01

Family

ID=21787358

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8888902708T Expired - Fee Related DE3875306T2 (de) 1987-02-24 1988-02-23 Immunosuppression bei der auf immunotoxin basierten behandlung von menschen.

Country Status (7)

Country Link
EP (1) EP0303681B1 (de)
JP (1) JPH01502909A (de)
KR (1) KR890700353A (de)
AT (1) ATE81467T1 (de)
AU (1) AU619740B2 (de)
DE (1) DE3875306T2 (de)
WO (1) WO1988006451A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9200417D0 (en) * 1992-01-09 1992-02-26 Bagshawe Kenneth D Cytotoxic drug therapy
AU5369798A (en) * 1996-11-27 1998-06-22 Bachem Bioscience, Inc. Shk toxin compositions and methods of use
US6593362B2 (en) 2001-05-21 2003-07-15 Guilford Pharmaceuticals Inc. Non-peptidic cyclophilin binding compounds and their use
US7833979B2 (en) 2005-04-22 2010-11-16 Amgen Inc. Toxin peptide therapeutic agents
GB0605395D0 (en) * 2006-03-16 2006-04-26 Norwegian Radium Hospital Res Anti-cancer therapy
TW200833840A (en) 2006-10-25 2008-08-16 Amgen Inc Toxin peptide therapeutic agents
WO2008125903A2 (en) * 2006-12-12 2008-10-23 Chaim Sheba Medical Center Method of inhibiting an undesired immune response
JP5591691B2 (ja) 2007-05-22 2014-09-17 アムジエン・インコーポレーテツド 生物活性を有する融合タンパク質を作製するための組成物及び方法
KR102283951B1 (ko) 2011-04-29 2021-08-02 셀렉타 바이오사이언시즈, 인크. 항원-특이적 이펙터 t 세포의 결실을 위한 관용원성 합성 나노운반체
EA201592103A3 (ru) 2013-05-03 2016-08-31 Селекта Байосайенсиз, Инк. Способы и композиции для усиления cd4+ регуляторных t-клеток
US11633422B2 (en) 2014-09-07 2023-04-25 Selecta Biosciences, Inc. Methods and compositions for attenuating anti-viral transfer vector immune responses
EP3592389A1 (de) 2017-03-11 2020-01-15 Selecta Biosciences, Inc. Verfahren und zusammensetzungen in zusammenhang mit einer kombinierten behandlung mit entzündungshemmenden mitteln und synthetischen nanoträgern mit einem immunsuppressivum

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2573656B1 (fr) * 1984-11-29 1987-02-27 Sanofi Sa Medicament comportant en tant qu'association au moins une immunotoxine et au moins un polymere contenant du mannose
FR2577135B1 (fr) * 1985-02-13 1989-12-15 Sanofi Sa Immunotoxines a longue duree d'action comportant un constituant glycopeptidique inactivant les ribosomes modifie sur ses motifs polysaccharidiques
FR2584294B1 (fr) * 1985-07-08 1992-02-21 Berdal Pascal Compositions pharmaceutiques a visee cytotrophique
WO1987003286A1 (en) * 1985-11-29 1987-06-04 The University Of Melbourne Ricin-antibody conjugates

Also Published As

Publication number Publication date
EP0303681A1 (de) 1989-02-22
JPH01502909A (ja) 1989-10-05
EP0303681A4 (de) 1989-12-28
KR890700353A (ko) 1989-04-24
EP0303681B1 (de) 1992-10-14
DE3875306T2 (de) 1993-04-01
WO1988006451A1 (en) 1988-09-07
AU1421488A (en) 1988-09-26
AU619740B2 (en) 1992-02-06
ATE81467T1 (de) 1992-10-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee