MX2010004705A - Derivados de piridazinona y uso de los mismos como inhibidores del receptor p2x7. - Google Patents

Derivados de piridazinona y uso de los mismos como inhibidores del receptor p2x7.

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Publication number
MX2010004705A
MX2010004705A MX2010004705A MX2010004705A MX2010004705A MX 2010004705 A MX2010004705 A MX 2010004705A MX 2010004705 A MX2010004705 A MX 2010004705A MX 2010004705 A MX2010004705 A MX 2010004705A MX 2010004705 A MX2010004705 A MX 2010004705A
Authority
MX
Mexico
Prior art keywords
receptor inhibitors
pyridazinone derivatives
receptor
pyridazinone
derivatives
Prior art date
Application number
MX2010004705A
Other languages
English (en)
Inventor
Yutaka Hirokawa
Yukihiro Shigeta
Masato Horikawa
Hiroshi Nagai
Kei Nagae
Tsuneo Watanabe
Megumi Io
Yusuke Matsuura
Junji Kamon
Kazuya Takeuchi
Original Assignee
Nissan Chemical Ind Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nissan Chemical Ind Ltd filed Critical Nissan Chemical Ind Ltd
Publication of MX2010004705A publication Critical patent/MX2010004705A/es

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    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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Abstract

Compuestos de piridazinona novedosos de fórmula (I), que inhiben el receptor purinérgico P2X7 y son útiles para la prevención, terapia y mejoramiento de enfermedades inflamatorias e inmunes. (Ver fórmula I).
MX2010004705A 2007-10-31 2008-10-30 Derivados de piridazinona y uso de los mismos como inhibidores del receptor p2x7. MX2010004705A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2007284189 2007-10-31
JP2008229921 2008-09-08
PCT/JP2008/070261 WO2009057827A1 (en) 2007-10-31 2008-10-30 Pyridazinone derivatives and use thereof as p2x7 receptor inhibitors

Publications (1)

Publication Number Publication Date
MX2010004705A true MX2010004705A (es) 2010-05-27

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Application Number Title Priority Date Filing Date
MX2010004705A MX2010004705A (es) 2007-10-31 2008-10-30 Derivados de piridazinona y uso de los mismos como inhibidores del receptor p2x7.

Country Status (13)

Country Link
US (1) US8440666B2 (es)
EP (1) EP2203429A1 (es)
JP (1) JP5423679B2 (es)
KR (1) KR20100084516A (es)
CN (1) CN101842359A (es)
AU (1) AU2008319735A1 (es)
CA (1) CA2699631A1 (es)
IL (1) IL205176A0 (es)
MX (1) MX2010004705A (es)
RU (1) RU2010121763A (es)
TW (1) TW200932237A (es)
WO (1) WO2009057827A1 (es)
ZA (1) ZA201001860B (es)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
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