|
ZA935110B
(en)
*
|
1992-07-17 |
1994-02-04 |
Smithkline Beecham Corp |
Rapamycin derivatives
|
|
ZA935111B
(en)
*
|
1992-07-17 |
1994-02-04 |
Smithkline Beecham Corp |
Rapamycin derivatives
|
|
USRE40596E1
(en)
*
|
1993-04-08 |
2008-12-02 |
Novartis Ag |
Rapamycin assay
|
|
GB9307491D0
(en)
|
1993-04-08 |
1993-06-02 |
Sandoz Ltd |
Organic compounds
|
|
US7279561B1
(en)
|
1993-04-23 |
2007-10-09 |
Wyeth |
Anti-rapamycin monoclonal antibodies
|
|
EP1181938B1
(en)
|
1993-04-23 |
2007-11-14 |
Wyeth |
Rapamycin conjugates and antibodies
|
|
USRE37421E1
(en)
|
1993-07-16 |
2001-10-23 |
Smithkline Beecham Corporation |
Rapamycin derivatives
|
|
PT1033128E
(pt)
*
|
1993-09-28 |
2008-08-08 |
Scherer Gmbh R P |
Fabrico de cápsulas de gelatina mole
|
|
JP4105761B2
(ja)
*
|
1993-11-19 |
2008-06-25 |
アボット・ラボラトリーズ |
ラパミシン(マクロライド)の半合成類似体免疫調節剤
|
|
US5527907A
(en)
*
|
1993-11-19 |
1996-06-18 |
Abbott Laboratories |
Macrolide immunomodulators
|
|
CZ284650B6
(cs)
*
|
1993-12-17 |
1999-01-13 |
Novartis Ag |
Nové demethoxyderiváty rapamycinu, způsob jejich přípravy a farmaceutický prostředek, který je obsahuje
|
|
GB9405350D0
(en)
*
|
1994-03-18 |
1994-05-04 |
Sandoz Ltd |
Organic compounds
|
|
GB2308546B
(en)
*
|
1994-10-26 |
1999-06-02 |
Novartis Ag |
Topical macrolide compositions
|
|
MY129435A
(en)
|
1994-10-26 |
2007-04-30 |
Novartis Ag |
Pharmaceutical microemulsion preconcentrates
|
|
US7205279B2
(en)
*
|
1995-10-25 |
2007-04-17 |
Novartis Ag |
Pharmaceutical compositions
|
|
US5561138A
(en)
*
|
1994-12-13 |
1996-10-01 |
American Home Products Corporation |
Method of treating anemia
|
|
GB9618952D0
(en)
*
|
1996-09-11 |
1996-10-23 |
Sandoz Ltd |
Process
|
|
US6187757B1
(en)
|
1995-06-07 |
2001-02-13 |
Ariad Pharmaceuticals, Inc. |
Regulation of biological events using novel compounds
|
|
KR100400620B1
(ko)
|
1995-06-09 |
2004-02-18 |
노파르티스 아게 |
라파마이신유도체
|
|
BE1009856A5
(fr)
|
1995-07-14 |
1997-10-07 |
Sandoz Sa |
Composition pharmaceutique sous la forme d'une dispersion solide comprenant un macrolide et un vehicule.
|
|
US5780462A
(en)
*
|
1995-12-27 |
1998-07-14 |
American Home Products Corporation |
Water soluble rapamycin esters
|
|
GB9601120D0
(en)
*
|
1996-01-19 |
1996-03-20 |
Sandoz Ltd |
Organic compounds
|
|
GB9606452D0
(en)
*
|
1996-03-27 |
1996-06-05 |
Sandoz Ltd |
Organic compounds
|
|
KR100616020B1
(ko)
*
|
1996-03-27 |
2007-01-31 |
노파르티스 아게 |
맥관장애및이종이식술에서의라파마이신유도체의용도
|
|
SI1208847T1
(sl)
*
|
1996-07-30 |
2007-06-30 |
Novartis Ag |
Farmacevtski sestavki za zdravljenje stanj zavračanja transplantatov in avtoimunskih ali vnetnih stanj
|
|
US5922730A
(en)
*
|
1996-09-09 |
1999-07-13 |
American Home Products Corporation |
Alkylated rapamycin derivatives
|
|
WO1998009970A2
(en)
*
|
1996-09-09 |
1998-03-12 |
American Home Products Corporation |
Alkylated rapamycin derivatives
|
|
GB9624038D0
(en)
*
|
1996-11-19 |
1997-01-08 |
Sandoz Ltd |
Organic compounds
|
|
US6220537B1
(en)
|
1997-03-07 |
2001-04-24 |
Daiwa Seiko, Inc. |
Fishing spinning reel having smoothly shaped rail portion
|
|
US6306166B1
(en)
*
|
1997-08-13 |
2001-10-23 |
Scimed Life Systems, Inc. |
Loading and release of water-insoluble drugs
|
|
RU2235554C2
(ru)
*
|
1998-03-06 |
2004-09-10 |
Новартис Аг |
Предварительно приготовленные эмульсионные концентраты, содержащие циклоспорин или макролид
|
|
ES2219000T3
(es)
*
|
1998-03-26 |
2004-11-16 |
Fujisawa Pharmaceutical Co., Ltd. |
Preparacion de liberacion sostenida de un compuesto macrolido.
|
|
US20050031611A1
(en)
*
|
1998-05-08 |
2005-02-10 |
Beth Israel Deaconess Medical Center |
Transplant tolerance by costimulation blockade and T-cell activation-induced apoptosis
|
|
US6015809A
(en)
*
|
1998-08-17 |
2000-01-18 |
American Home Products Corporation |
Photocyclized rapamycin
|
|
BR9913052A
(pt)
*
|
1998-08-17 |
2001-05-08 |
American Home Prod |
Rapamicinas fotocilizadas
|
|
GB9826882D0
(en)
*
|
1998-12-07 |
1999-01-27 |
Novartis Ag |
Organic compounds
|
|
US7276506B2
(en)
*
|
1998-12-28 |
2007-10-02 |
4 Aza Bioscience Nv |
Immunosuppressive effects of pteridine derivatives
|
|
US6946465B2
(en)
*
|
1999-02-02 |
2005-09-20 |
4 Aza Bioscience Nv |
Immunosuppressive effects of pteridine derivatives
|
|
US6318654B1
(en)
|
1999-03-07 |
2001-11-20 |
Daiwa Seiko, Inc. |
Spinning reel for fishing
|
|
US7063857B1
(en)
|
1999-04-30 |
2006-06-20 |
Sucampo Ag |
Use of macrolide compounds for the treatment of dry eye
|
|
WO2000067773A2
(en)
|
1999-05-10 |
2000-11-16 |
Novartis Ag |
Combinations of immunosupressive agents for the treatment or prevention of graft rejections
|
|
USD440626S1
(en)
|
1999-06-08 |
2001-04-17 |
Daiwa Seiko, Inc. |
Line slider for a spinning fishing reel
|
|
AU6643200A
(en)
*
|
1999-08-18 |
2001-03-13 |
American Home Products Corporation |
Water soluble sdz-rad esters
|
|
US6331547B1
(en)
|
1999-08-18 |
2001-12-18 |
American Home Products Corporation |
Water soluble SDZ RAD esters
|
|
US7067526B1
(en)
|
1999-08-24 |
2006-06-27 |
Ariad Gene Therapeutics, Inc. |
28-epirapalogs
|
|
ES2219388T3
(es)
|
1999-08-24 |
2004-12-01 |
Ariad Gene Therapeutics, Inc. |
28-epi-rapalogos.
|
|
US6790228B2
(en)
|
1999-12-23 |
2004-09-14 |
Advanced Cardiovascular Systems, Inc. |
Coating for implantable devices and a method of forming the same
|
|
US7807211B2
(en)
|
1999-09-03 |
2010-10-05 |
Advanced Cardiovascular Systems, Inc. |
Thermal treatment of an implantable medical device
|
|
US20070032853A1
(en)
*
|
2002-03-27 |
2007-02-08 |
Hossainy Syed F |
40-O-(2-hydroxy)ethyl-rapamycin coated stent
|
|
US6277983B1
(en)
|
2000-09-27 |
2001-08-21 |
American Home Products Corporation |
Regioselective synthesis of rapamycin derivatives
|
|
CA2397354C
(en)
*
|
2000-01-14 |
2011-07-19 |
The Trustees Of The University Of Pennsylvania |
O-methylated rapamycin derivatives for alleviation and inhibition of lymphoproliferative disorders
|
|
GB0008785D0
(en)
|
2000-04-10 |
2000-05-31 |
Novartis Ag |
Organic compounds
|
|
US8236048B2
(en)
|
2000-05-12 |
2012-08-07 |
Cordis Corporation |
Drug/drug delivery systems for the prevention and treatment of vascular disease
|
|
US6670355B2
(en)
|
2000-06-16 |
2003-12-30 |
Wyeth |
Method of treating cardiovascular disease
|
|
CN100448487C
(zh)
|
2000-08-11 |
2009-01-07 |
惠氏公司 |
治疗雌激素受体阳性癌的方法
|
|
ATE411321T1
(de)
|
2000-09-19 |
2008-10-15 |
Wyeth Corp |
Wasserlösliche rapamycin-ester
|
|
US6399625B1
(en)
|
2000-09-27 |
2002-06-04 |
Wyeth |
1-oxorapamycins
|
|
JP5100951B2
(ja)
|
2000-09-29 |
2012-12-19 |
コーディス・コーポレイション |
被覆医用器具
|
|
US6440991B1
(en)
*
|
2000-10-02 |
2002-08-27 |
Wyeth |
Ethers of 7-desmethlrapamycin
|
|
US6399626B1
(en)
|
2000-10-02 |
2002-06-04 |
Wyeth |
Hydroxyesters of 7-desmethylrapamycin
|
|
HU230302B1
(hu)
|
2000-10-20 |
2015-12-28 |
Eisai R&D Management Co., Ltd. |
Nitrogéntartalmú aromás származékok és ezeket tartalmazó gyógyászati készítmények
|
|
US7754208B2
(en)
|
2001-01-17 |
2010-07-13 |
Trubion Pharmaceuticals, Inc. |
Binding domain-immunoglobulin fusion proteins
|
|
LT3351246T
(lt)
*
|
2001-02-19 |
2019-07-10 |
Novartis Pharma Ag |
Rapamicino darinys, skirtas kieto naviko, susijusio su nereguliuojama angiogeneze, gydymui
|
|
AU2016206379B2
(en)
*
|
2001-02-19 |
2017-09-14 |
Novartis Ag |
Cancer Treatment
|
|
AU2011226833B9
(en)
*
|
2001-02-19 |
2014-07-03 |
Novartis Ag |
Cancer treatment
|
|
AU2005201004A1
(en)
*
|
2001-02-19 |
2005-03-24 |
Novartis Ag |
Cancer treatment
|
|
TWI296196B
(en)
*
|
2001-04-06 |
2008-05-01 |
Wyeth Corp |
Antineoplastic combinations
|
|
TWI233359B
(en)
*
|
2001-04-06 |
2005-06-01 |
Wyeth Corp |
Pharmaceutical composition for treating neoplasm
|
|
US6613083B2
(en)
|
2001-05-02 |
2003-09-02 |
Eckhard Alt |
Stent device and method
|
|
US7033604B2
(en)
|
2001-07-06 |
2006-04-25 |
Sucampo Ag |
Composition for topical administration
|
|
JP4202250B2
(ja)
|
2001-07-25 |
2008-12-24 |
バイオマリン ファーマシューティカル インコーポレイテッド |
血液脳関門輸送を調節するための組成物および方法
|
|
US6939376B2
(en)
*
|
2001-11-05 |
2005-09-06 |
Sun Biomedical, Ltd. |
Drug-delivery endovascular stent and method for treating restenosis
|
|
US7682387B2
(en)
|
2002-04-24 |
2010-03-23 |
Biosensors International Group, Ltd. |
Drug-delivery endovascular stent and method for treating restenosis
|
|
EP1458405A1
(en)
*
|
2001-11-21 |
2004-09-22 |
Sucampo AG |
Use of fk506 and analogues for treating allergic diseases
|
|
US20030176455A1
(en)
*
|
2002-03-13 |
2003-09-18 |
Wyeth |
Method of inhibiting cell death
|
|
US20040024450A1
(en)
*
|
2002-04-24 |
2004-02-05 |
Sun Biomedical, Ltd. |
Drug-delivery endovascular stent and method for treating restenosis
|
|
ES2316758T3
(es)
|
2002-05-16 |
2009-04-16 |
Novartis Ag |
Uso de aglutinantes del receptor edg en el cancer.
|
|
BR0312691A
(pt)
|
2002-07-16 |
2005-05-10 |
Biotica Tech Ltd |
Métodos para converter uma cepa hospedeira em uma cepa recombinante, para gerar uma cepa recombinante contendo agrupamento biossintéticos, para produzir um análogo de um ligando de fbkp, para construir uma coleção de colÈnias de cepas recombinantes e para preparar uma coleção combinatorial de ligando de fkbp, coleção de análogos de ligando fbkp, cepa recombinante, método para gerar análogos de ligandos de fbkp, composto, e, uso do mesmo
|
|
WO2004011000A1
(en)
|
2002-07-30 |
2004-02-05 |
Wyeth |
Parenteral formulations containing a rapamycin hydroxyester
|
|
ES2428354T3
(es)
*
|
2002-09-18 |
2013-11-07 |
Trustees Of The University Of Pennsylvania |
Rapamicina para usar en la inhibición o prevención de la neovascularización coroidea
|
|
TWI335311B
(en)
|
2002-09-24 |
2011-01-01 |
Novartis Ag |
Organic compounds
|
|
WO2004060283A2
(en)
|
2002-12-16 |
2004-07-22 |
Nitromed, Inc. |
Nitrosated and nitrosylated rapamycin compounds, compositions and methods of use
|
|
JP2006516548A
(ja)
|
2002-12-30 |
2006-07-06 |
アンジオテック インターナショナル アクツィエン ゲゼルシャフト |
迅速ゲル化ポリマー組成物からの薬物送達法
|
|
AR042938A1
(es)
*
|
2003-02-06 |
2005-07-06 |
Wyeth Corp |
Uso del cci-779 en el tratamiento de la fibrosis hepatica
|
|
US20090093875A1
(en)
|
2007-05-01 |
2009-04-09 |
Abbott Laboratories |
Drug eluting stents with prolonged local elution profiles with high local concentrations and low systemic concentrations
|
|
AR043504A1
(es)
*
|
2003-03-17 |
2005-08-03 |
Novartis Ag |
Composiciones farmaceuticas que comprenden rapamicina para el tratamiento de enfermedades inflamatorias
|
|
GB0307867D0
(en)
*
|
2003-04-04 |
2003-05-14 |
Novartis Ag |
Pharmaceutical composition
|
|
US20070155771A1
(en)
*
|
2003-04-11 |
2007-07-05 |
David Rubinsztein |
Methods and means for treating protein conformational disorders
|
|
PL1615640T3
(pl)
*
|
2003-04-22 |
2007-05-31 |
Wyeth Corp |
Kombinacje przeciwnowotworowe
|
|
US7160867B2
(en)
*
|
2003-05-16 |
2007-01-09 |
Isotechnika, Inc. |
Rapamycin carbohydrate derivatives
|
|
US20050118344A1
(en)
|
2003-12-01 |
2005-06-02 |
Pacetti Stephen D. |
Temperature controlled crimping
|
|
AU2004255340B2
(en)
*
|
2003-07-08 |
2008-05-01 |
Novartis Ag |
Use of rapamycin and rapamycin derivatives for the treatment of bone loss
|
|
PT1663244E
(pt)
*
|
2003-09-12 |
2007-11-15 |
4 Aza Ip Nv |
Derivados de ptiridina para o tratamento de doenças relacionadas com o tnf-alfa
|
|
AU2004274026A1
(en)
|
2003-09-18 |
2005-03-31 |
Macusight, Inc. |
Transscleral delivery
|
|
US20070032477A1
(en)
*
|
2003-10-17 |
2007-02-08 |
Waer Mark J A |
Pteridine derivatives useful for making pharmaceutical compositions
|
|
US7220755B2
(en)
*
|
2003-11-12 |
2007-05-22 |
Biosensors International Group, Ltd. |
42-O-alkoxyalkyl rapamycin derivatives and compositions comprising same
|
|
US9114198B2
(en)
|
2003-11-19 |
2015-08-25 |
Advanced Cardiovascular Systems, Inc. |
Biologically beneficial coatings for implantable devices containing fluorinated polymers and methods for fabricating the same
|
|
GB0327840D0
(en)
*
|
2003-12-01 |
2003-12-31 |
Novartis Ag |
Organic compounds
|
|
ES2315745T3
(es)
*
|
2004-03-01 |
2009-04-01 |
Terumo Kabushiki Kaisha |
Procedimiento para la fabricacion de derivados o-alquilados de rapamicina.
|
|
WO2005088307A1
(en)
|
2004-03-10 |
2005-09-22 |
Seradyn Inc. |
Immunoassays for everolimus
|
|
AR047988A1
(es)
*
|
2004-03-11 |
2006-03-15 |
Wyeth Corp |
Combinaciones antineoplásicas de cci-779 y rituximab
|
|
US8551512B2
(en)
*
|
2004-03-22 |
2013-10-08 |
Advanced Cardiovascular Systems, Inc. |
Polyethylene glycol/poly(butylene terephthalate) copolymer coated devices including EVEROLIMUS
|
|
US8778014B1
(en)
|
2004-03-31 |
2014-07-15 |
Advanced Cardiovascular Systems, Inc. |
Coatings for preventing balloon damage to polymer coated stents
|
|
BRPI0509810A
(pt)
*
|
2004-04-14 |
2007-09-18 |
Wyeth Corp |
método para a sìntese regioespecìfica de um 42-hemiéster de rapamicina ou um 32-hemiéster de fk-506 com um ácido dicarboxìlico, 42-hemiéster de rapamicina regioespecìfica, anticorpo de rapamicina, produto, e, 32-hemiéster de fk506 regioespecìfico
|
|
CN1946852A
(zh)
*
|
2004-04-27 |
2007-04-11 |
惠氏公司 |
利用雷帕霉素特异性甲基化酶标记雷帕霉素
|
|
CA2571710A1
(en)
|
2004-06-24 |
2006-11-02 |
Nicholas Valiante |
Small molecule immunopotentiators and assays for their detection
|
|
US8709469B2
(en)
|
2004-06-30 |
2014-04-29 |
Abbott Cardiovascular Systems Inc. |
Anti-proliferative and anti-inflammatory agent combination for treatment of vascular disorders with an implantable medical device
|
|
GB0417852D0
(en)
|
2004-08-11 |
2004-09-15 |
Biotica Tech Ltd |
Production of polyketides and other natural products
|
|
JP5117190B2
(ja)
*
|
2004-08-27 |
2013-01-09 |
コーディス・コーポレイション |
溶媒を含有しない非晶質ラパマイシン
|
|
EP1797881B1
(en)
|
2004-09-17 |
2009-04-15 |
Eisai R&D Management Co., Ltd. |
Medicinal composition with improved stability and reduced gelation properties
|
|
US7901451B2
(en)
|
2004-09-24 |
2011-03-08 |
Biosensors International Group, Ltd. |
Drug-delivery endovascular stent and method for treating restenosis
|
|
US8313763B2
(en)
|
2004-10-04 |
2012-11-20 |
Tolmar Therapeutics, Inc. |
Sustained delivery formulations of rapamycin compounds
|
|
WO2006041942A2
(en)
*
|
2004-10-04 |
2006-04-20 |
Qlt Usa, Inc. |
Ocular delivery of polymeric delivery formulations
|
|
BRPI0518079A
(pt)
*
|
2004-10-28 |
2008-11-04 |
Wyeth Corp |
usos de um inibidor de mtor, de uma rapamicina, e de 42-éster de rapamicina com ácido 3-hidróxi-2- (hidroximetil) -2-metilpropiÈnico, composição farmacêutica, e, embalagem farmacêutica
|
|
US8021849B2
(en)
*
|
2004-11-05 |
2011-09-20 |
Siemens Healthcare Diagnostics Inc. |
Methods and kits for the determination of sirolimus in a sample
|
|
WO2006053754A1
(en)
*
|
2004-11-19 |
2006-05-26 |
Novartis Ag |
COMBINATIONS OF ANTI-ATHEROSCLEROTIC PEPTIDES AND AN mTOR INHIBITING AGENT AND THEIR METHODS OF USE
|
|
WO2006071966A2
(en)
*
|
2004-12-29 |
2006-07-06 |
The Brigham And Women's Hospital, Inc. |
Rapamycin compounds in the treatment of neurofibromatosis type 1
|
|
US20060258698A1
(en)
|
2005-02-09 |
2006-11-16 |
Sreenivasu Mudumba |
Liquid formulations for treatment of diseases or conditions
|
|
US8663639B2
(en)
|
2005-02-09 |
2014-03-04 |
Santen Pharmaceutical Co., Ltd. |
Formulations for treating ocular diseases and conditions
|
|
GB0503936D0
(en)
|
2005-02-25 |
2005-04-06 |
San Raffaele Centro Fond |
Method
|
|
GB0504544D0
(en)
|
2005-03-04 |
2005-04-13 |
Novartis Ag |
Organic compounds
|
|
EP1856131A1
(en)
|
2005-03-07 |
2007-11-21 |
Wyeth |
Oxepane isomer of 42-o-(2-hydroxy)ethyl-rapamycin
|
|
WO2006095173A2
(en)
|
2005-03-11 |
2006-09-14 |
Biotica Technology Limited |
Medical uses of 39-desmethoxyrapamycin and analogues thereof
|
|
US20100061994A1
(en)
*
|
2005-03-11 |
2010-03-11 |
Rose Mary Sheridan |
Medical uses of 39-desmethoxyrapamycin and analogues thereof
|
|
GT200600148A
(es)
*
|
2005-04-14 |
2006-11-22 |
|
Metodos para el tratamiento y la prevencion de fibrosis
|
|
US7189582B2
(en)
*
|
2005-04-27 |
2007-03-13 |
Dade Behring Inc. |
Compositions and methods for detection of sirolimus
|
|
CA2789262C
(en)
|
2005-04-28 |
2016-10-04 |
Proteus Digital Health, Inc. |
Pharma-informatics system
|
|
CN101227927A
(zh)
*
|
2005-05-31 |
2008-07-23 |
诺瓦提斯公司 |
HMG-CoA还原酶抑制剂和mTOR抑制剂的组合
|
|
US20070004767A1
(en)
*
|
2005-06-30 |
2007-01-04 |
Gutmann David H |
Methods for treating neurofibromatosis 1
|
|
EP1909973B1
(en)
|
2005-07-15 |
2018-08-22 |
Micell Technologies, Inc. |
Polymer coatings containing drug powder of controlled morphology
|
|
US20090062909A1
(en)
|
2005-07-15 |
2009-03-05 |
Micell Technologies, Inc. |
Stent with polymer coating containing amorphous rapamycin
|
|
KR20080041206A
(ko)
|
2005-07-20 |
2008-05-09 |
노파르티스 아게 |
피리미딜아미노벤즈아미드와 mtor 키나제 억제제의조합물
|
|
SI1912675T1
(sl)
|
2005-07-25 |
2014-07-31 |
Emergent Product Development Seattle, Llc |
zmanjšanje števila celic B z uporabo molekul, ki se specifično vežejo na CD37 in CD20
|
|
EP2281901B1
(en)
|
2005-08-02 |
2013-11-27 |
Eisai R&D Management Co., Ltd. |
Anti-tumour pharmaceutical composition with angiogenesis inhibitors
|
|
EP1919954B1
(en)
|
2005-08-30 |
2016-10-19 |
University of Miami |
Immunomodulating tumor necrosis factor receptor 25 (tnfr25) agonists, antagonists and immunotoxins
|
|
EP1776970A1
(en)
|
2005-10-12 |
2007-04-25 |
Albert Schömig |
Implant with multiple coating
|
|
AU2006311877A1
(en)
|
2005-11-04 |
2007-05-18 |
Wyeth Llc |
Antineoplastic combinations with mTOR inhibitor, herceptin, and/orHKI-272
|
|
GB0523659D0
(en)
*
|
2005-11-21 |
2005-12-28 |
Novartis Ag |
Organic compounds
|
|
KR20080077989A
(ko)
*
|
2005-12-20 |
2008-08-26 |
와이어쓰 |
약물의 불순물 조절을 통한 cci-779 제형의 안정성 조절
|
|
AU2007204410A1
(en)
*
|
2006-01-12 |
2007-07-19 |
Novartis Ag |
Combination of mTOR inhibitor and antipolate compound
|
|
US20070173923A1
(en)
*
|
2006-01-20 |
2007-07-26 |
Savage Douglas R |
Drug reservoir stent
|
|
AU2007211613C1
(en)
*
|
2006-02-02 |
2018-01-04 |
Novartis Ag |
Tuberous Sclerosis treatment
|
|
BRPI0707612B8
(pt)
|
2006-02-09 |
2021-05-25 |
Macusight Inc |
vaso lacrado e formulações líquidas contidas no mesmo
|
|
US7678901B2
(en)
*
|
2006-02-28 |
2010-03-16 |
Wyeth |
Rapamycin analogs containing an antioxidant moiety
|
|
US7622477B2
(en)
*
|
2006-02-28 |
2009-11-24 |
Cordis Corporation |
Isomers and 42-epimers of rapamycin alkyl ether analogs, methods of making and using the same
|
|
PE20080138A1
(es)
*
|
2006-03-07 |
2008-03-05 |
Wyeth Corp |
Procesos para preparar conjugados de polietilen glicol solubles en agua de inmunosupresores macrolidos
|
|
EP2001466B1
(en)
|
2006-03-23 |
2016-01-06 |
Santen Pharmaceutical Co., Ltd |
Low-dose rapamycin for the treatment of vascular permeability-related diseases
|
|
CA2996768C
(en)
|
2006-04-26 |
2020-12-08 |
Micell Technologies, Inc. |
Coatings containing multiple drugs
|
|
EP2036557B1
(en)
|
2006-05-18 |
2015-10-21 |
Eisai R&D Management Co., Ltd. |
Antitumor agent for thyroid cancer
|
|
GB0609962D0
(en)
*
|
2006-05-19 |
2006-06-28 |
Biotica Tech Ltd |
Novel compounds
|
|
GB0609963D0
(en)
*
|
2006-05-19 |
2006-06-28 |
Biotica Tech Ltd |
Novel compounds
|
|
AU2007315790A1
(en)
*
|
2006-06-30 |
2008-05-08 |
Interface Biologics, Inc. |
Bioresponsive polymers
|
|
US9259426B2
(en)
|
2006-07-20 |
2016-02-16 |
Gilead Sciences, Inc. |
4,6-di- and 2,4,6-trisubstituted quinazoline derivatives useful for treating viral infections
|
|
WO2008009079A2
(en)
*
|
2006-07-20 |
2008-01-24 |
Gilead Sciences, Inc. |
Substituted pteridines useful for the treatment and prevention of viral infections
|
|
WO2008016633A2
(en)
*
|
2006-08-02 |
2008-02-07 |
Ariad Gene Therapeutics, Inc. |
Combination therapy
|
|
US20080051691A1
(en)
*
|
2006-08-28 |
2008-02-28 |
Wyeth |
Implantable shunt or catheter enabling gradual delivery of therapeutic agents
|
|
CN101511793B
(zh)
|
2006-08-28 |
2011-08-03 |
卫材R&D管理有限公司 |
针对未分化型胃癌的抗肿瘤剂
|
|
US10695327B2
(en)
|
2006-09-13 |
2020-06-30 |
Elixir Medical Corporation |
Macrocyclic lactone compounds and methods for their use
|
|
US8088789B2
(en)
|
2006-09-13 |
2012-01-03 |
Elixir Medical Corporation |
Macrocyclic lactone compounds and methods for their use
|
|
JP6049160B2
(ja)
|
2006-09-13 |
2016-12-27 |
エリクシアー メディカル コーポレイション |
大環状ラクトン化合物およびその使用方法
|
|
US8067055B2
(en)
*
|
2006-10-20 |
2011-11-29 |
Biosensors International Group, Ltd. |
Drug-delivery endovascular stent and method of use
|
|
US20080097591A1
(en)
|
2006-10-20 |
2008-04-24 |
Biosensors International Group |
Drug-delivery endovascular stent and method of use
|
|
CN101522691B
(zh)
|
2006-11-27 |
2012-08-22 |
泰尔茂株式会社 |
O-烷基化雷帕霉素衍生物的制备方法及o-烷基化雷帕霉素衍生物
|
|
US11426494B2
(en)
|
2007-01-08 |
2022-08-30 |
MT Acquisition Holdings LLC |
Stents having biodegradable layers
|
|
CN101711137B
(zh)
|
2007-01-08 |
2014-10-22 |
米歇尔技术公司 |
具有可生物降解层的支架
|
|
NZ588816A
(en)
|
2007-01-21 |
2011-11-25 |
Hemoteq Ag |
Medical device for the treatment of stenoses of corporal lumina and for the prevention of impending restenoses
|
|
AU2008211952B2
(en)
|
2007-01-29 |
2012-07-19 |
Eisai R & D Management Co., Ltd. |
Composition for treatment of undifferentiated-type of gastric cancer
|
|
US8795627B2
(en)
|
2007-03-21 |
2014-08-05 |
Raptor Pharmaceuticals Inc. |
Treatment of liver disorders by administration of RAP conjugates
|
|
TW200845960A
(en)
*
|
2007-04-05 |
2008-12-01 |
Wyeth Corp |
Wortmannin-rapalog conjugate and uses thereof
|
|
TW200901989A
(en)
*
|
2007-04-10 |
2009-01-16 |
Wyeth Corp |
Anti-tumor activity of CCI-779 in papillary renal cell cancer
|
|
US9433516B2
(en)
|
2007-04-17 |
2016-09-06 |
Micell Technologies, Inc. |
Stents having controlled elution
|
|
US9192697B2
(en)
|
2007-07-03 |
2015-11-24 |
Hemoteq Ag |
Balloon catheter for treating stenosis of body passages and for preventing threatening restenosis
|
|
JP5599712B2
(ja)
|
2007-10-05 |
2014-10-01 |
インターフェース バイオロジクス,インコーポレーテッド |
オリゴフッ素化架橋ポリマーおよびそれの使用
|
|
WO2009049426A1
(en)
|
2007-10-19 |
2009-04-23 |
Interface Biologics Inc. |
Self-eliminating coatings
|
|
JP5638244B2
(ja)
|
2007-11-09 |
2014-12-10 |
エーザイ・アール・アンド・ディー・マネジメント株式会社 |
血管新生阻害物質と抗腫瘍性白金錯体との併用
|
|
CN103480047B
(zh)
|
2007-11-14 |
2015-02-18 |
生物传感器国际集团有限公司 |
自动化涂覆设备和方法
|
|
WO2009089549A1
(en)
|
2008-01-11 |
2009-07-16 |
Massachusetts Eye & Ear Infirmary |
Conditional-stop dimerizable caspase transgenic animals
|
|
WO2009114010A1
(en)
*
|
2008-03-11 |
2009-09-17 |
Elixir Medical Corporation |
Macrocyclic lactone compounds and methods for their use
|
|
US20100048524A1
(en)
|
2008-03-14 |
2010-02-25 |
Angela Brodie |
Novel C-17-Heteroaryl Steroidal CYP17 Inhibitors/Antiandrogens;Synthesis In Vitro Biological Activities, Pharmacokinetics and Antitumor Activity
|
|
US8685995B2
(en)
|
2008-03-21 |
2014-04-01 |
The University Of Chicago |
Treatment with opioid antagonists and mTOR inhibitors
|
|
SG189772A1
(en)
|
2008-04-11 |
2013-05-31 |
Trubion Pharmaceuticals Inc |
Cd37 immunotherapeutic and combination with bifunctional chemotherapeutic thereof
|
|
US20110098241A1
(en)
*
|
2008-04-14 |
2011-04-28 |
Poniard Pharmaceuticals, Inc. |
Rapamycin analogs as anti-cancer agents
|
|
SG192524A1
(en)
|
2008-04-17 |
2013-08-30 |
Micell Technologies Inc |
Stents having bioabsorbable layers
|
|
SG10201406263SA
(en)
|
2008-06-20 |
2015-02-27 |
Novartis Ag |
Paediatric compositions for treating multiple sclerosis
|
|
US8765162B2
(en)
|
2008-06-30 |
2014-07-01 |
Abbott Cardiovascular Systems Inc. |
Poly(amide) and poly(ester-amide) polymers and drug delivery particles and coatings containing same
|
|
CA2730995C
(en)
|
2008-07-17 |
2016-11-22 |
Micell Technologies, Inc. |
Drug delivery medical device
|
|
US8092822B2
(en)
|
2008-09-29 |
2012-01-10 |
Abbott Cardiovascular Systems Inc. |
Coatings including dexamethasone derivatives and analogs and olimus drugs
|
|
BRPI0919794A2
(pt)
*
|
2008-10-03 |
2015-12-15 |
Elixir Medical Corp |
dispositivo para uso intracorpóreo, e, composto
|
|
EP2337788B1
(en)
*
|
2008-10-17 |
2016-03-23 |
Wisconsin Alumni Research Foundation |
Method of making biologically active alpha-beta peptides
|
|
US20120064143A1
(en)
|
2008-11-11 |
2012-03-15 |
The Board Of Regents Of The University Of Texas System |
Inhibition of mammalian target of rapamycin
|
|
PA8855601A1
(es)
|
2008-12-23 |
2010-07-27 |
|
Forformidatos de nucleósidos
|
|
US8551973B2
(en)
|
2008-12-23 |
2013-10-08 |
Gilead Pharmasset Llc |
Nucleoside analogs
|
|
US8716263B2
(en)
|
2008-12-23 |
2014-05-06 |
Gilead Pharmasset Llc |
Synthesis of purine nucleosides
|
|
JP5643770B2
(ja)
*
|
2009-01-21 |
2014-12-17 |
バイオコン・リミテッドBiocon Limited |
シロリムスの安定性の決定方法およびその安定形態の調製方法
|
|
CN102686600A
(zh)
|
2009-02-05 |
2012-09-19 |
托凯药业股份有限公司 |
甾体cyp17抑制剂/抗雄激素物质的新型药物前体
|
|
WO2010103130A2
(en)
|
2009-03-13 |
2010-09-16 |
Katholieke Universiteit Leuven, K.U.Leuven R&D |
Novel bicyclic heterocycles
|
|
CA2757276C
(en)
|
2009-04-01 |
2017-06-06 |
Micell Technologies, Inc. |
Coated stents
|
|
WO2010120599A2
(en)
|
2009-04-16 |
2010-10-21 |
Merck Sharp & Dohme Corp. |
Compositions and methods for treating cancer
|
|
CN110075069A
(zh)
|
2009-05-06 |
2019-08-02 |
实验室护肤股份有限公司 |
包含活性剂-磷酸钙颗粒复合物的皮肤递送组合物及其应用
|
|
EP2451496B1
(en)
|
2009-07-10 |
2015-07-22 |
Boston Scientific Scimed, Inc. |
Use of nanocrystals for a drug delivery balloon
|
|
EP2453834A4
(en)
|
2009-07-16 |
2014-04-16 |
Micell Technologies Inc |
MEDICAL DEVICE DISPENSING MEDICINE
|
|
JP5933434B2
(ja)
|
2009-07-17 |
2016-06-08 |
ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. |
薬剤送達バルーンの製造方法
|
|
SG178125A1
(en)
|
2009-08-03 |
2012-03-29 |
Univ Miami |
Method for in vivo expansion of t regulatory cells
|
|
WO2011050016A1
(en)
|
2009-10-23 |
2011-04-28 |
Eli Lilly And Company |
Akt inhibitors
|
|
WO2011053938A1
(en)
|
2009-10-30 |
2011-05-05 |
Ariad Pharmaceuticals, Inc. |
Methods and compositions for treating cancer
|
|
US9283211B1
(en)
|
2009-11-11 |
2016-03-15 |
Rapamycin Holdings, Llc |
Oral rapamycin preparation and use for stomatitis
|
|
WO2015161139A1
(en)
|
2014-04-16 |
2015-10-22 |
Rapamycin Holdings, Llc |
Oral rapamycin preparation and use for stomatitis
|
|
US20120232087A1
(en)
|
2009-11-18 |
2012-09-13 |
Silvia Buonamici |
Methods and compositions for treating solid tumors and other malignancies
|
|
CN102933658A
(zh)
|
2009-12-18 |
2013-02-13 |
界面生物公司 |
从自组装涂层局部递送药物
|
|
CN102127092B
(zh)
*
|
2010-01-18 |
2013-04-17 |
东南大学 |
依维莫斯的制备
|
|
US11369498B2
(en)
|
2010-02-02 |
2022-06-28 |
MT Acquisition Holdings LLC |
Stent and stent delivery system with improved deliverability
|
|
JP2013521002A
(ja)
|
2010-03-05 |
2013-06-10 |
プレジデント アンド フェロウズ オブ ハーバード カレッジ |
誘導樹状細胞組成物及びその使用
|
|
WO2011123668A2
(en)
|
2010-03-31 |
2011-10-06 |
Pharmasset, Inc. |
Stereoselective synthesis of phosphorus containing actives
|
|
US20130035336A1
(en)
|
2010-04-13 |
2013-02-07 |
Novartis Ag |
Combination comprising a cyclin dependent kinase 4 or cyclin dependent kinase (cdk4/6) inhibitor for treating cancer
|
|
NZ602807A
(en)
|
2010-04-16 |
2014-02-28 |
Novartis Ag |
4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1h-benzimidazol-2-yl]-1h-quinolin-2-one and an mtor inhibitor
|
|
CA2797110C
(en)
|
2010-04-22 |
2020-07-21 |
Micell Technologies, Inc. |
Stents and other devices having extracellular matrix coating
|
|
JP6042801B2
(ja)
|
2010-04-27 |
2016-12-14 |
ロシュ グリクアート アーゲー |
mTORインヒビターとのアフコシル化CD20抗体の併用療法
|
|
GB201012889D0
(en)
|
2010-08-02 |
2010-09-15 |
Univ Leuven Kath |
Antiviral activity of novel bicyclic heterocycles
|
|
MX2012014776A
(es)
|
2010-06-25 |
2013-01-29 |
Eisai R&D Man Co Ltd |
Agente antitumoral que emplea compuestos con efecto inhibidor de cinasas combinados.
|
|
WO2012009684A2
(en)
|
2010-07-16 |
2012-01-19 |
Micell Technologies, Inc. |
Drug delivery medical device
|
|
EP2611476B1
(en)
|
2010-09-02 |
2016-08-10 |
Boston Scientific Scimed, Inc. |
Coating process for drug delivery balloons using heat-induced rewrap memory
|
|
GB201015411D0
(en)
|
2010-09-15 |
2010-10-27 |
Univ Leuven Kath |
Anti-cancer activity of novel bicyclic heterocycles
|
|
US20120077778A1
(en)
|
2010-09-29 |
2012-03-29 |
Andrea Bourdelais |
Ladder-Frame Polyether Conjugates
|
|
CN102464669B
(zh)
*
|
2010-11-17 |
2014-04-16 |
浙江海正药业股份有限公司 |
无定形依维莫司及其制备方法
|
|
WO2012066502A1
(en)
*
|
2010-11-19 |
2012-05-24 |
Biocon Limited |
Processes for preparation of everolimus and intermediates thereof
|
|
EP4230631A3
(en)
|
2011-02-04 |
2024-03-27 |
Synthon B.V. |
Process for making trisubstituted silyloxyethyl triflates
|
|
ES2547916T3
(es)
|
2011-02-18 |
2015-10-09 |
Novartis Pharma Ag |
Terapia de combinación de inhibidores de mTOR/JAK
|
|
CN102174053B
(zh)
*
|
2011-03-09 |
2014-04-16 |
成都雅途生物技术有限公司 |
依维莫司的纯化方法
|
|
PL2683406T3
(pl)
|
2011-03-11 |
2019-11-29 |
Beth Israel Deaconess Medical Ct Inc |
Przeciwciała anty-cd40 i ich zastosowania
|
|
EP2508525A1
(en)
|
2011-04-05 |
2012-10-10 |
Bayer Pharma Aktiengesellschaft |
Substituted 2,3-dihydroimidazo[1,2-c]quinazoline salts
|
|
MX2013009931A
(es)
|
2011-04-18 |
2013-10-01 |
Eisai R&D Man Co Ltd |
Agentes terapeuticos contra tumores.
|
|
BR112013027486A2
(pt)
|
2011-04-25 |
2017-02-14 |
Novartis Ag |
combinação de um inibidor de fosfatidilinositol-3-cinase (pi3k) e um inibidor de mtor
|
|
EP2702173A1
(en)
|
2011-04-25 |
2014-03-05 |
OSI Pharmaceuticals, LLC |
Use of emt gene signatures in cancer drug discovery, diagnostics, and treatment
|
|
US9945862B2
(en)
|
2011-06-03 |
2018-04-17 |
Eisai R&D Management Co., Ltd. |
Biomarkers for predicting and assessing responsiveness of thyroid and kidney cancer subjects to lenvatinib compounds
|
|
EP2717884A1
(en)
|
2011-06-06 |
2014-04-16 |
Chevron Phillips Chemical Company LP |
Use of metallocene compounds for cancer treatment
|
|
EP2532740A1
(en)
|
2011-06-11 |
2012-12-12 |
Michael Schmück |
Antigen-specific CD4+ and CD8+ central-memory T cell preparations for adoptive T cell therapy
|
|
WO2013012689A1
(en)
|
2011-07-15 |
2013-01-24 |
Micell Technologies, Inc. |
Drug delivery medical device
|
|
WO2013013708A1
(en)
|
2011-07-26 |
2013-01-31 |
Fundació Institut D'investigació Biomèdica De Bellvitge |
Treatment of acute rejection in renal transplant
|
|
US20130028895A1
(en)
|
2011-07-27 |
2013-01-31 |
Gerald Wulf |
Exosome inhibiting agents and uses thereof
|
|
WO2013022458A1
(en)
|
2011-08-05 |
2013-02-14 |
Boston Scientific Scimed, Inc. |
Methods of converting amorphous drug substance into crystalline form
|
|
WO2013028208A1
(en)
|
2011-08-25 |
2013-02-28 |
Boston Scientific Scimed, Inc. |
Medical device with crystalline drug coating
|
|
CN102268015B
(zh)
*
|
2011-08-30 |
2013-08-28 |
成都摩尔生物医药有限公司 |
一种依维莫司的合成方法
|
|
GB201115665D0
(en)
|
2011-09-09 |
2011-10-26 |
Univ Leuven Kath |
Autoimmune and inflammatory disorder therapy
|
|
KR101643219B1
(ko)
|
2011-10-06 |
2016-07-27 |
노파르티스 아게 |
40-o-(2-히드록시)에틸-라파마이신을 포함하는 제약 조성물
|
|
US10188772B2
(en)
|
2011-10-18 |
2019-01-29 |
Micell Technologies, Inc. |
Drug delivery medical device
|
|
EP2589383A1
(en)
|
2011-11-06 |
2013-05-08 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Berlin |
FKBP subtype-specific rapamycin analogue for use in treatment of diseases
|
|
GB201122305D0
(en)
|
2011-12-23 |
2012-02-01 |
Biotica Tech Ltd |
Novel compound
|
|
RU2014149145A
(ru)
|
2012-05-23 |
2016-07-20 |
Ф. Хоффманн-Ля Рош Аг |
Композиции и способы получения и применения эндодермальных клеток и гепатоцитов
|
|
CN102786534A
(zh)
*
|
2012-05-25 |
2012-11-21 |
上海现代制药股份有限公司 |
一种依维莫司的制备方法
|
|
ES2574522T3
(es)
|
2012-06-08 |
2016-06-20 |
Biotronik Ag |
Ésteres 40-O-hidrocarburo cíclico de rapamicina, composiciones y procedimientos
|
|
WO2013192367A1
(en)
|
2012-06-22 |
2013-12-27 |
Novartis Ag |
Neuroendocrine tumor treatment
|
|
CN103705925B
(zh)
|
2012-09-29 |
2018-03-30 |
段磊 |
抑制PI3K/AKT/mTOR信号通路的药物组合
|
|
US9750728B2
(en)
|
2012-09-29 |
2017-09-05 |
Targeted Therapeutics, Llc |
Method and pharmaceutical composition for inhibiting PI3K/AKT/mTOR signaling pathway
|
|
WO2014059295A1
(en)
|
2012-10-12 |
2014-04-17 |
The Board Of Regents Of The University Of Texas System |
Use of mtor inhibitors to treat vascular cognitive impairment
|
|
US20150258127A1
(en)
|
2012-10-31 |
2015-09-17 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for preventing antiphospholipid syndrome (aps)
|
|
US9757432B2
(en)
|
2012-11-14 |
2017-09-12 |
Ohio State Innovation Foundation |
Materials and methods useful for treating glioblastorna
|
|
AU2012395673A1
(en)
*
|
2012-11-30 |
2014-08-14 |
Hangzhou Zylox Pharma Co., Ltd. |
Rapamycin analogs and methods for making same
|
|
US9334239B2
(en)
|
2012-12-21 |
2016-05-10 |
Eisai R&D Management Co., Ltd. |
Amorphous form of quinoline derivative, and method for producing same
|
|
KR20210041631A
(ko)
|
2013-01-09 |
2021-04-15 |
유니버시티 오브 마이애미 |
TL1A-Ig 융합 단백질을 사용한 T 조절 세포의 조절을 위한 조성물 및 방법
|
|
CN110269959A
(zh)
|
2013-03-12 |
2019-09-24 |
脉胜医疗技术公司 |
可生物吸收的生物医学植入物
|
|
US20160030401A1
(en)
|
2013-03-13 |
2016-02-04 |
The Board Of Regents Of The University Of Texas System |
Use of mtor inhibitors for prevention of intestinal polyp growth and cancer
|
|
CA2904170A1
(en)
|
2013-03-14 |
2014-09-25 |
University Of Maryland, Baltimore |
Androgen receptor down-regulating agents and uses thereof
|
|
US10098871B2
(en)
*
|
2013-03-15 |
2018-10-16 |
Leslie B. Gordon |
Combination therapies for treatment of laminopathies, cellular aging, and atherosclerosis
|
|
TW201503912A
(zh)
|
2013-03-19 |
2015-02-01 |
Novartis Ag |
包含癌莫事(everolimus)之醫藥組合物
|
|
EP2994758B1
(en)
|
2013-05-08 |
2017-12-20 |
Opthea Limited |
Biomarkers for age-related macular degeneration (amd)
|
|
US10517861B2
(en)
|
2013-05-14 |
2019-12-31 |
Eisai R&D Management Co., Ltd. |
Biomarkers for predicting and assessing responsiveness of endometrial cancer subjects to lenvatinib compounds
|
|
AU2014265460B2
(en)
|
2013-05-15 |
2018-10-18 |
Micell Technologies, Inc. |
Bioabsorbable biomedical implants
|
|
CA2905229C
(en)
|
2013-06-11 |
2023-10-10 |
Clontech Laboratories, Inc. |
Protein enriched microvesicles and methods of making and using the same
|
|
RU2691728C2
(ru)
*
|
2013-06-20 |
2019-06-18 |
Новартис Аг |
Алкилирование сульфонатом алкилфторалкила
|
|
CN103360411B
(zh)
*
|
2013-07-17 |
2015-09-30 |
成都雅途生物技术有限公司 |
依维莫司结晶提纯方法
|
|
JP2016528252A
(ja)
|
2013-08-12 |
2016-09-15 |
トーカイ ファーマシューティカルズ, インコーポレイテッド |
アンドロゲン標的治療を使用する新生物障害の処置のためのバイオマーカー
|
|
US9580758B2
(en)
|
2013-11-12 |
2017-02-28 |
Luc Montagnier |
System and method for the detection and treatment of infection by a microbial agent associated with HIV infection
|
|
US20150140036A1
(en)
|
2013-11-13 |
2015-05-21 |
Novartis Institutes For Biomedical Research, Inc. |
Low, immune enhancing, dose mtor inhibitors and uses thereof
|
|
US10640569B2
(en)
|
2013-12-19 |
2020-05-05 |
Novartis Ag |
Human mesothelin chimeric antigen receptors and uses thereof
|
|
EP4420663A3
(en)
|
2013-12-20 |
2024-10-30 |
Novartis AG |
Regulatable chimeric antigen receptor
|
|
KR101529963B1
(ko)
*
|
2013-12-27 |
2015-06-19 |
주식회사 종근당바이오 |
에베로리무스의 제조방법 및 이의 중간체
|
|
DK3089737T3
(da)
|
2013-12-31 |
2021-12-13 |
Rapamycin Holdings Llc |
Orale rapamycin-nanopartikelpræparater og anvendelse.
|
|
US9700544B2
(en)
|
2013-12-31 |
2017-07-11 |
Neal K Vail |
Oral rapamycin nanoparticle preparations
|
|
EP3094314B1
(en)
|
2014-01-16 |
2021-06-23 |
MUSC Foundation For Research Development |
Targeted nanocarriers for the administration of immunosuppressive agents
|
|
US20170165246A1
(en)
|
2014-02-11 |
2017-06-15 |
Novartis Ag |
Pharmaceutical combinations comprising a pi3k inhibitor for the treatment of cancer
|
|
ES2857226T3
(es)
|
2014-03-15 |
2021-09-28 |
Novartis Ag |
Receptor de antígeno quimérico regulable
|
|
WO2015142675A2
(en)
|
2014-03-15 |
2015-09-24 |
Novartis Ag |
Treatment of cancer using chimeric antigen receptor
|
|
CN103848849B
(zh)
*
|
2014-03-24 |
2016-02-24 |
上海医药工业研究院 |
依维莫司的制备工艺
|
|
CA2943609A1
(en)
|
2014-03-27 |
2015-10-01 |
The Brigham And Women's Hospital, Inc. |
Metabolically-activated drug conjugates to overcome resistance in cancer therapy
|
|
LT3129470T
(lt)
|
2014-04-07 |
2021-07-12 |
Novartis Ag |
Vėžio gydymas naudojant anti-cd19 chimerinį antigeno receptorių
|
|
US10258639B2
(en)
|
2014-05-06 |
2019-04-16 |
Research Development Foundation |
Methods for treating insulin resistance and for sensitizing patients to GLP1 agonist therapy
|
|
CN105254646A
(zh)
*
|
2014-05-28 |
2016-01-20 |
上海博邦医药科技有限公司 |
一种制备依维莫司的方法
|
|
EP3148564B1
(en)
|
2014-06-02 |
2020-01-08 |
Children's Medical Center Corporation |
Methods and compositions for immunomodulation
|
|
EP3193915A1
(en)
|
2014-07-21 |
2017-07-26 |
Novartis AG |
Combinations of low, immune enhancing. doses of mtor inhibitors and cars
|
|
SG10201913765YA
(en)
|
2014-07-21 |
2020-03-30 |
Novartis Ag |
Treatment of cancer using a cd33 chimeric antigen receptor
|
|
WO2016014553A1
(en)
|
2014-07-21 |
2016-01-28 |
Novartis Ag |
Sortase synthesized chimeric antigen receptors
|
|
JP7054622B2
(ja)
|
2014-07-21 |
2022-04-14 |
ノバルティス アーゲー |
ヒト化抗bcmaキメラ抗原受容体を使用した癌の処置
|
|
EP3660042B1
(en)
|
2014-07-31 |
2023-01-11 |
Novartis AG |
Subset-optimized chimeric antigen receptor-containing t-cells
|
|
US9938297B2
(en)
|
2014-08-04 |
2018-04-10 |
Cipia Limited |
Process for the synthesis of everolimus and intermediates thereof
|
|
CN117164657A
(zh)
|
2014-08-12 |
2023-12-05 |
莫纳什大学 |
定向淋巴的前药
|
|
JP6919118B2
(ja)
|
2014-08-14 |
2021-08-18 |
ノバルティス アーゲー |
GFRα−4キメラ抗原受容体を用いる癌の治療
|
|
AU2015305531B2
(en)
|
2014-08-19 |
2021-05-20 |
Novartis Ag |
Anti-CD123 chimeric antigen receptor (CAR) for use in cancer treatment
|
|
CN106660964B
(zh)
|
2014-08-28 |
2021-09-03 |
卫材R&D管理有限公司 |
高纯度喹啉衍生物及其生产方法
|
|
CN107073066B
(zh)
|
2014-09-11 |
2021-09-17 |
加利福尼亚大学董事会 |
mTORC1抑制剂
|
|
KR20250067191A
(ko)
|
2014-09-17 |
2025-05-14 |
노파르티스 아게 |
입양 면역요법을 위한 키메라 수용체에 의한 세포독성 세포의 표적화
|
|
CN114107424A
(zh)
|
2014-10-08 |
2022-03-01 |
诺华股份有限公司 |
预测针对嵌合抗原受体疗法的治疗应答性的生物标志及其用途
|
|
WO2016066608A1
(en)
|
2014-10-28 |
2016-05-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for treatment of pulmonary cell senescence and peripheral aging
|
|
EP3246036B1
(en)
|
2014-10-28 |
2021-10-13 |
Koushi Yamaguchi |
Medicine for improving pregnancy-induced hypertension syndrome
|
|
US10603325B2
(en)
|
2014-10-29 |
2020-03-31 |
University Of Maryland |
Methods of treating age-related symptoms in mammals and compositions therefor
|
|
CN104478898A
(zh)
*
|
2014-11-18 |
2015-04-01 |
连云港恒运医药科技有限公司 |
依维莫司及其中间体的制备方法
|
|
WO2016135740A1
(en)
|
2015-02-23 |
2016-09-01 |
Natco Pharma Limited |
Process for preparing stable oral compositions of everolimus
|
|
PL3263106T3
(pl)
|
2015-02-25 |
2024-04-02 |
Eisai R&D Management Co., Ltd. |
Sposób tłumienia goryczy pochodnej chinoliny
|
|
KR102662228B1
(ko)
|
2015-03-04 |
2024-05-02 |
머크 샤프 앤드 돔 코포레이션 |
암을 치료하기 위한 pd-1 길항제 및 vegfr/fgfr/ret 티로신 키나제 억제제의 조합
|
|
EP3722297A1
(en)
|
2015-03-04 |
2020-10-14 |
Gilead Sciences, Inc. |
Toll-like receptor modulating 4,6-diamino-pyrido[3,2-d]pyrimidine compounds
|
|
EP3283619B1
(en)
|
2015-04-17 |
2023-04-05 |
Novartis AG |
Methods for improving the efficacy and expansion of chimeric antigen receptor-expressing cells
|
|
US12128069B2
(en)
|
2015-04-23 |
2024-10-29 |
The Trustees Of The University Of Pennsylvania |
Treatment of cancer using chimeric antigen receptor and protein kinase a blocker
|
|
EP3297629A1
(en)
|
2015-05-20 |
2018-03-28 |
Novartis AG |
Pharmaceutical combination of everolimus with dactolisib
|
|
CN104892632B
(zh)
*
|
2015-06-03 |
2017-12-26 |
道中道(菏泽)制药有限公司 |
一种晶体形式的依维莫司及其制备方法
|
|
ES2886107T3
(es)
|
2015-06-16 |
2021-12-16 |
Prism Biolab Co Ltd |
Antineoplásico
|
|
EP3109250A1
(en)
|
2015-06-23 |
2016-12-28 |
Synbias Pharma AG |
Method for the synthesis of rapamycin derivatives
|
|
WO2017029391A1
(en)
|
2015-08-20 |
2017-02-23 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
New method for treating cancer
|
|
AU2016309356B2
(en)
|
2015-08-20 |
2021-06-24 |
Eisai R&D Management Co., Ltd. |
Tumor therapeutic agent
|
|
BR112018004296B1
(pt)
|
2015-09-04 |
2020-05-05 |
Primatope Therapeutics Inc |
anticorpos anti-cd40 humanizados e usos dos mesmos
|
|
JP7118888B2
(ja)
|
2015-09-08 |
2022-08-16 |
モナッシュ ユニバーシティ |
リンパ指向性プロドラッグ
|
|
HK1254630A1
(zh)
|
2015-11-11 |
2019-07-26 |
Novartis Ag |
肌抑素拮抗剂的用途、含有它们的组合及其用途
|
|
CN105566348A
(zh)
*
|
2015-12-31 |
2016-05-11 |
哈药集团技术中心 |
一种依维莫司的制备方法
|
|
CN114949250A
(zh)
|
2016-04-14 |
2022-08-30 |
斯宾纳克生物科学公司 |
用于递送治疗剂的组合物、药物组合物、制备方法以及用途
|
|
CN116077439A
(zh)
|
2016-04-29 |
2023-05-09 |
西奈山伊坎医学院 |
靶向先天免疫系统以诱导长期耐受性及解决动脉粥样硬化中的巨噬细胞累积
|
|
JP6855470B2
(ja)
|
2016-05-27 |
2021-04-07 |
日本化薬株式会社 |
ラパマイシン又はその誘導体を含有する医薬組成物
|
|
EP3487878A4
(en)
|
2016-07-20 |
2020-03-25 |
University of Utah Research Foundation |
CAR-T CD229 LYMPHOCYTES AND METHODS OF USE
|
|
ES2906581T3
(es)
|
2016-09-02 |
2022-04-19 |
Gilead Sciences Inc |
Compuestos moduladores de los receptores tipo Toll
|
|
US10640499B2
(en)
|
2016-09-02 |
2020-05-05 |
Gilead Sciences, Inc. |
Toll like receptor modulator compounds
|
|
AU2017341047B2
(en)
|
2016-10-07 |
2024-10-10 |
Novartis Ag |
Chimeric antigen receptors for the treatment of cancer
|
|
BR112019010470A2
(pt)
|
2016-11-23 |
2019-09-10 |
Novartis Ag |
métodos de realce de resposta imune com everolimo, dactolisib ou ambos
|
|
US20200081010A1
(en)
|
2016-12-02 |
2020-03-12 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Methods and compositions for diagnosing renal cell carcinoma
|
|
MY196830A
(en)
|
2016-12-22 |
2023-05-03 |
Amgen Inc |
Kras g12c inhibitors and methods of using the same
|
|
GB201701087D0
(en)
|
2017-01-23 |
2017-03-08 |
Univ Leuven Kath |
Novel prodrugs of mizoribine
|
|
MX380144B
(es)
|
2017-02-08 |
2025-03-12 |
Eisai R&D Man Co Ltd |
Composicion farmaceutica de tratamiento de tumores.
|
|
CN110603038A
(zh)
*
|
2017-02-10 |
2019-12-20 |
塔姆山治疗公司 |
雷帕霉素类似物
|
|
WO2018201056A1
(en)
|
2017-04-28 |
2018-11-01 |
Novartis Ag |
Cells expressing a bcma-targeting chimeric antigen receptor, and combination therapy with a gamma secretase inhibitor
|
|
WO2018213352A1
(en)
|
2017-05-15 |
2018-11-22 |
C.R. Bard, Inc. |
Medical device with drug-eluting coating and intermediate layer
|
|
CA3061888A1
(en)
|
2017-05-16 |
2018-11-22 |
Eisai R&D Management Co., Ltd. |
Treatment of hepatocellular carcinoma
|
|
JOP20190272A1
(ar)
|
2017-05-22 |
2019-11-21 |
Amgen Inc |
مثبطات kras g12c وطرق لاستخدامها
|
|
US20200129486A1
(en)
|
2017-06-26 |
2020-04-30 |
Inserm (Institut National De La Santé Et De La Recherche Medicale) |
Methods and pharmaceutical compositions for the treatment of olmsted syndrome
|
|
EP3652306A1
(en)
|
2017-07-13 |
2020-05-20 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for increasing expansion and immunosuppressive capacity of a population of cd8+cd45rclow/-tregs
|
|
US11883497B2
(en)
|
2017-08-29 |
2024-01-30 |
Puretech Lyt, Inc. |
Lymphatic system-directing lipid prodrugs
|
|
EP3675838A4
(en)
|
2017-08-29 |
2021-04-21 |
PureTech LYT, Inc. |
LIPID PRODRUGS DIRECTED TO THE LYMPHATIC SYSTEM
|
|
EP4403175A3
(en)
|
2017-09-08 |
2024-10-02 |
Amgen Inc. |
Inhibitors of kras g12c and methods of using the same
|
|
UY37900A
(es)
|
2017-09-26 |
2019-04-30 |
Novartis Ag |
Nuevos derivados de rapamicina
|
|
CN108047265A
(zh)
*
|
2017-11-24 |
2018-05-18 |
成都海创药业有限公司 |
一种依维莫司中间体的制备纯化方法
|
|
US11304954B2
(en)
|
2017-12-19 |
2022-04-19 |
Puretech Lyt, Inc. |
Lipid prodrugs of mycophenolic acid and uses thereof
|
|
US11608345B1
(en)
|
2017-12-19 |
2023-03-21 |
Puretech Lyt, Inc. |
Lipid prodrugs of rapamycin and its analogs and uses thereof
|
|
US10596165B2
(en)
|
2018-02-12 |
2020-03-24 |
resTORbio, Inc. |
Combination therapies
|
|
WO2019210153A1
(en)
|
2018-04-27 |
2019-10-31 |
Novartis Ag |
Car t cell therapies with enhanced efficacy
|
|
BR112020022201A2
(pt)
|
2018-05-01 |
2021-02-02 |
Revolution Medicines, Inc. |
análogos de rapamicina ligada a c40, c28, e c-32 como inibidores de mtor
|
|
WO2019213282A1
(en)
|
2018-05-01 |
2019-11-07 |
Novartis Ag |
Biomarkers for evaluating car-t cells to predict clinical outcome
|
|
IL312291A
(en)
|
2018-05-01 |
2024-06-01 |
Revolution Medicines Inc |
C-26-linked rapamycin analogs as MTOR inhibitors
|
|
ES2995514T3
(en)
|
2018-05-04 |
2025-02-10 |
Amgen Inc |
Kras g12c inhibitors and methods of using the same
|
|
CA3098574A1
(en)
|
2018-05-04 |
2019-11-07 |
Amgen Inc. |
Kras g12c inhibitors and methods of using the same
|
|
ES2986917T3
(es)
|
2018-05-10 |
2024-11-13 |
Amgen Inc |
Inhibidores de KRAS G12C para el tratamiento del cáncer
|
|
CN112638436A
(zh)
|
2018-05-22 |
2021-04-09 |
界面生物公司 |
用于将药物递送至血管壁的组合物和方法
|
|
TWI869346B
(zh)
|
2018-05-30 |
2025-01-11 |
瑞士商諾華公司 |
Entpd2抗體、組合療法、及使用該等抗體和組合療法之方法
|
|
EP3802535B1
(en)
|
2018-06-01 |
2022-12-14 |
Amgen, Inc |
Kras g12c inhibitors and methods of using the same
|
|
MA52780A
(fr)
|
2018-06-11 |
2021-04-14 |
Amgen Inc |
Inhibiteurs de kras g12c pour le traitement du cancer
|
|
AU2019336588B2
(en)
|
2018-06-12 |
2022-07-28 |
Amgen Inc. |
KRAS G12C inhibitors encompassing a piperazine ring and use thereof in the treatment of cancer
|
|
CA3100724A1
(en)
|
2018-06-13 |
2019-12-19 |
Novartis Ag |
B-cell maturation antigen protein (bcma) chimeric antigen receptors and uses thereof
|
|
CN108676014A
(zh)
*
|
2018-06-15 |
2018-10-19 |
国药集团川抗制药有限公司 |
纯化依维莫司中间体的方法以及制备依维莫司的方法
|
|
WO2020023417A1
(en)
|
2018-07-23 |
2020-01-30 |
Enclear Therapies, Inc. |
Methods of treating neurological disorders
|
|
CN113164557A
(zh)
|
2018-07-23 |
2021-07-23 |
因柯利尔疗法公司 |
治疗神经性病症的方法
|
|
EP3849545A1
(en)
|
2018-09-10 |
2021-07-21 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Methods for the treatment of neurofibromatosis
|
|
CN113167798A
(zh)
|
2018-10-05 |
2021-07-23 |
卫材R&D管理有限公司 |
用于包含乐伐替尼和依维莫司的组合疗法的生物标志物
|
|
US11541152B2
(en)
|
2018-11-14 |
2023-01-03 |
Lutonix, Inc. |
Medical device with drug-eluting coating on modified device surface
|
|
JP7516029B2
(ja)
|
2018-11-16 |
2024-07-16 |
アムジエン・インコーポレーテツド |
Kras g12c阻害剤化合物の重要な中間体の改良合成法
|
|
JP7454572B2
(ja)
|
2018-11-19 |
2024-03-22 |
アムジエン・インコーポレーテツド |
Kras g12c阻害剤及びその使用方法
|
|
JP7377679B2
(ja)
|
2018-11-19 |
2023-11-10 |
アムジエン・インコーポレーテツド |
がん治療のためのkrasg12c阻害剤及び1種以上の薬学的に活性な追加の薬剤を含む併用療法
|
|
LT3898637T
(lt)
|
2018-12-18 |
2025-03-10 |
Novartis Ag |
Rapamicino dariniai
|
|
AU2019403488B2
(en)
|
2018-12-20 |
2025-07-24 |
Amgen Inc. |
KIF18A inhibitors
|
|
US12441705B2
(en)
|
2018-12-20 |
2025-10-14 |
Amgen Inc. |
KIF18A inhibitors
|
|
EA202191730A1
(ru)
|
2018-12-20 |
2021-08-24 |
Эмджен Инк. |
Ингибиторы kif18a
|
|
MX2021007157A
(es)
|
2018-12-20 |
2021-08-16 |
Amgen Inc |
Heteroarilamidas utiles como inhibidores de kif18a.
|
|
CN113195000A
(zh)
|
2018-12-21 |
2021-07-30 |
第一三共株式会社 |
抗体-药物缀合物和激酶抑制剂的组合
|
|
KR102643707B1
(ko)
*
|
2019-01-22 |
2024-03-04 |
에오비안 파마슈티컬스, 인크. |
Mtorc 조절제 및 이의 용도
|
|
KR20210146288A
(ko)
|
2019-03-01 |
2021-12-03 |
레볼루션 메디슨즈, 인크. |
이환식 헤테로사이클릴 화합물 및 이의 용도
|
|
MX2021010319A
(es)
|
2019-03-01 |
2021-12-10 |
Revolution Medicines Inc |
Compuestos biciclicos de heteroarilo y usos de estos.
|
|
US20220176084A1
(en)
|
2019-04-08 |
2022-06-09 |
Bard Peripheral Vascular, Inc. |
Medical device with drug-eluting coating on modified device surface
|
|
EP3952947A4
(en)
|
2019-04-11 |
2024-07-03 |
Enclear Therapies, Inc. |
METHODS FOR IMPROVING CSF AND DEVICES AND SYSTEMS THEREFOR
|
|
TWI751516B
(zh)
|
2019-04-17 |
2022-01-01 |
美商基利科學股份有限公司 |
類鐸受體調節劑之固體形式
|
|
TWI751517B
(zh)
|
2019-04-17 |
2022-01-01 |
美商基利科學股份有限公司 |
類鐸受體調節劑之固體形式
|
|
EP3738593A1
(en)
|
2019-05-14 |
2020-11-18 |
Amgen, Inc |
Dosing of kras inhibitor for treatment of cancers
|
|
NZ782284A
(en)
|
2019-05-21 |
2024-11-29 |
Amgen Inc |
Solid state forms
|
|
TWI879779B
(zh)
|
2019-06-28 |
2025-04-11 |
美商基利科學股份有限公司 |
類鐸受體調節劑化合物的製備方法
|
|
TW202114681A
(zh)
|
2019-07-02 |
2021-04-16 |
美商eFFECTOR醫療公司 |
轉譯抑制劑及其用途
|
|
WO2021026099A1
(en)
|
2019-08-02 |
2021-02-11 |
Amgen Inc. |
Kif18a inhibitors
|
|
MX2022001302A
(es)
|
2019-08-02 |
2022-03-02 |
Amgen Inc |
Inhibidores de kif18a.
|
|
JP7771047B2
(ja)
|
2019-08-02 |
2025-11-17 |
アムジエン・インコーポレーテツド |
Kif18a阻害剤
|
|
AU2020324963A1
(en)
|
2019-08-02 |
2022-02-24 |
Amgen Inc. |
KIF18A inhibitors
|
|
KR20220054347A
(ko)
|
2019-08-26 |
2022-05-02 |
아비나스 오퍼레이션스, 인코포레이티드 |
에스트로겐 수용체 분해제로서의 테트라히드로나프탈렌 유도체로 유방암을 치료하는 방법
|
|
US20220402916A1
(en)
|
2019-09-18 |
2022-12-22 |
Merck Sharp & Dohme Corp. |
Small molecule inhibitors of kras g12c mutant
|
|
CN114502590A
(zh)
|
2019-09-18 |
2022-05-13 |
诺华股份有限公司 |
Entpd2抗体、组合疗法、以及使用这些抗体和组合疗法的方法
|
|
AU2020369569A1
(en)
|
2019-10-24 |
2022-04-14 |
Amgen Inc. |
Pyridopyrimidine derivatives useful as KRAS G12C and KRAS G12D inhibitors in the treatment of cancer
|
|
US11697657B2
(en)
|
2019-10-28 |
2023-07-11 |
Merck Sharp & Dohme Llc |
Small molecule inhibitors of KRAS G12C mutant
|
|
CN115551500A
(zh)
|
2019-10-31 |
2022-12-30 |
大鹏药品工业株式会社 |
4-氨基丁-2-烯酰胺衍生物及其盐
|
|
EP4054720A1
(en)
|
2019-11-04 |
2022-09-14 |
Revolution Medicines, Inc. |
Ras inhibitors
|
|
US11608346B2
(en)
|
2019-11-04 |
2023-03-21 |
Revolution Medicines, Inc. |
Ras inhibitors
|
|
US11566007B2
(en)
|
2019-11-04 |
2023-01-31 |
Revolution Medicines, Inc. |
Ras inhibitors
|
|
EP4620531A3
(en)
|
2019-11-08 |
2025-11-26 |
Revolution Medicines, Inc. |
Bicyclic heteroaryl compounds and uses thereof
|
|
CA3161156A1
(en)
|
2019-11-14 |
2021-05-20 |
Amgen Inc. |
Improved synthesis of kras g12c inhibitor compound
|
|
BR112022009390A2
(pt)
|
2019-11-14 |
2022-08-09 |
Amgen Inc |
Síntese melhorada de composto inibidor de kras g12c
|
|
JP2023505100A
(ja)
|
2019-11-27 |
2023-02-08 |
レボリューション メディシンズ インコーポレイテッド |
共有ras阻害剤及びその使用
|
|
WO2021106231A1
(en)
|
2019-11-29 |
2021-06-03 |
Taiho Pharmaceutical Co., Ltd. |
A compound having inhibitory activity against kras g12d mutation
|
|
CN118767143A
(zh)
|
2019-12-12 |
2024-10-15 |
听治疗有限责任公司 |
用于预防和治疗听力损失的组合物和方法
|
|
WO2021142026A1
(en)
|
2020-01-07 |
2021-07-15 |
Revolution Medicines, Inc. |
Shp2 inhibitor dosing and methods of treating cancer
|
|
CN115348864A
(zh)
|
2020-02-05 |
2022-11-15 |
纯技术Lyt股份有限公司 |
神经甾体的脂质前药
|
|
WO2021215544A1
(en)
|
2020-04-24 |
2021-10-28 |
Taiho Pharmaceutical Co., Ltd. |
Kras g12d protein inhibitors
|
|
WO2021215545A1
(en)
|
2020-04-24 |
2021-10-28 |
Taiho Pharmaceutical Co., Ltd. |
Anticancer combination therapy with n-(1-acryloyl-azetidin-3-yl)-2-((1h-indazol-3-yl)amino)methyl)-1h-imidazole-5-carboxamide inhibitor of kras-g12c
|
|
EP4183395A4
(en)
|
2020-07-15 |
2024-07-24 |
Taiho Pharmaceutical Co., Ltd. |
PYRIMIDINE COMPOUND-CONTAINING COMBINATION FOR USE IN TUMOR TREATMENT
|
|
IL301062A
(en)
|
2020-09-03 |
2023-05-01 |
Revolution Medicines Inc |
Use of sos1 inhibitors to treat malignancies with shp2 mutations
|
|
CR20230165A
(es)
|
2020-09-15 |
2023-06-02 |
Revolution Medicines Inc |
Derivados indólicos como inhibidores de ras en el tratamiento del cáncer
|
|
AU2021355470A1
(en)
|
2020-09-29 |
2023-06-01 |
Enclear Therapies, Inc. |
Subarachnoid fluid management method and system
|
|
AR124449A1
(es)
|
2020-12-22 |
2023-03-29 |
Qilu Regor Therapeutics Inc |
Inhibidores de sos1 y usos de los mismos
|
|
US11859021B2
(en)
|
2021-03-19 |
2024-01-02 |
Icahn School Of Medicine At Mount Sinai |
Compounds for regulating trained immunity, and their methods of use
|
|
CR20230558A
(es)
|
2021-05-05 |
2024-01-24 |
Revolution Medicines Inc |
Inhibidores de ras para el tratamiento del cáncer
|
|
CN118561952A
(zh)
|
2021-05-05 |
2024-08-30 |
锐新医药公司 |
Ras抑制剂
|
|
CN117500811A
(zh)
|
2021-05-05 |
2024-02-02 |
锐新医药公司 |
共价ras抑制剂及其用途
|
|
WO2022250170A1
(en)
|
2021-05-28 |
2022-12-01 |
Taiho Pharmaceutical Co., Ltd. |
Small molecule inhibitors of kras mutated proteins
|
|
EP4370160A1
(en)
|
2021-07-15 |
2024-05-22 |
President And Fellows Of Harvard College |
Compositions and methods relating to cells with adhered particles
|
|
AR127308A1
(es)
|
2021-10-08 |
2024-01-10 |
Revolution Medicines Inc |
Inhibidores ras
|
|
EP4448526A1
(en)
|
2021-12-17 |
2024-10-23 |
Genzyme Corporation |
Pyrazolopyrazine compounds as shp2 inhibitors
|
|
EP4227307A1
(en)
|
2022-02-11 |
2023-08-16 |
Genzyme Corporation |
Pyrazolopyrazine compounds as shp2 inhibitors
|
|
WO2023172858A1
(en)
|
2022-03-07 |
2023-09-14 |
Amgen Inc. |
A process for preparing 4-methyl-2-propan-2-yl-pyridine-3-carbonitrile
|
|
JP2025510572A
(ja)
|
2022-03-08 |
2025-04-15 |
レボリューション メディシンズ インコーポレイテッド |
免疫不応性肺癌を治療するための方法
|
|
CN119604293A
(zh)
|
2022-05-25 |
2025-03-11 |
锐新医药公司 |
用mTOR抑制剂治疗癌症的方法
|
|
EP4536364A1
(en)
|
2022-06-10 |
2025-04-16 |
Revolution Medicines, Inc. |
Macrocyclic ras inhibitors
|
|
JP2025521677A
(ja)
|
2022-07-06 |
2025-07-10 |
アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル |
増殖性糸球体腎炎を処置するための方法
|
|
WO2024028433A1
(en)
|
2022-08-04 |
2024-02-08 |
Institut National de la Santé et de la Recherche Médicale |
Methods for the treatment of lymphoproliferative disorders
|
|
JP2025536257A
(ja)
|
2022-10-14 |
2025-11-05 |
ブラック ダイアモンド セラピューティクス,インコーポレイティド |
イソキノリンまたは6-aza-キノリン誘導体を使用してがんを治療する方法
|
|
JP2025539034A
(ja)
|
2022-11-11 |
2025-12-03 |
アストラゼネカ・アクチエボラーグ |
癌の治療のための併用療法
|
|
WO2024167904A1
(en)
|
2023-02-07 |
2024-08-15 |
Arvinas Operations, Inc. |
Dosage regimens of estrogen receptor degraders in combination with an mtor inhibitor
|
|
AU2024241633A1
(en)
|
2023-03-30 |
2025-11-06 |
Revolution Medicines, Inc. |
Compositions for inducing ras gtp hydrolysis and uses thereof
|
|
AR132338A1
(es)
|
2023-04-07 |
2025-06-18 |
Revolution Medicines Inc |
Inhibidores de ras
|
|
WO2024211712A1
(en)
|
2023-04-07 |
2024-10-10 |
Revolution Medicines, Inc. |
Condensed macrocyclic compounds as ras inhibitors
|
|
KR20250172857A
(ko)
|
2023-04-14 |
2025-12-09 |
레볼루션 메디슨즈, 인크. |
Ras 억제제의 결정형
|
|
AU2024252105A1
(en)
|
2023-04-14 |
2025-10-16 |
Revolution Medicines, Inc. |
Crystalline forms of ras inhibitors, compositions containing the same, and methods of use thereof
|
|
WO2024229406A1
(en)
|
2023-05-04 |
2024-11-07 |
Revolution Medicines, Inc. |
Combination therapy for a ras related disease or disorder
|
|
CN116813641A
(zh)
*
|
2023-06-09 |
2023-09-29 |
杭州华东医药集团康润制药有限公司 |
一种依维莫司的制备方法
|
|
WO2025034702A1
(en)
|
2023-08-07 |
2025-02-13 |
Revolution Medicines, Inc. |
Rmc-6291 for use in the treatment of ras protein-related disease or disorder
|
|
TW202515582A
(zh)
|
2023-08-24 |
2025-04-16 |
日商大塚製藥股份有限公司 |
西區嘧啶(cedazuridine)之固定劑量組合
|
|
TW202530228A
(zh)
|
2023-10-12 |
2025-08-01 |
美商銳新醫藥公司 |
Ras抑制劑
|
|
US12466840B2
(en)
|
2023-10-20 |
2025-11-11 |
Merck Sharp & Dohme Llc |
Small molecule inhibitors of KRAS proteins
|
|
WO2025137507A1
(en)
|
2023-12-22 |
2025-06-26 |
Regor Pharmaceuticals, Inc. |
Sos1 inhibitors and uses thereof
|
|
WO2025171296A1
(en)
|
2024-02-09 |
2025-08-14 |
Revolution Medicines, Inc. |
Ras inhibitors
|
|
WO2025240847A1
(en)
|
2024-05-17 |
2025-11-20 |
Revolution Medicines, Inc. |
Ras inhibitors
|
|
WO2025255438A1
(en)
|
2024-06-07 |
2025-12-11 |
Revolution Medicines, Inc. |
Methods of treating a ras protein-related disease or disorder
|