|
ZA935111B
(en)
*
|
1992-07-17 |
1994-02-04 |
Smithkline Beecham Corp |
Rapamycin derivatives
|
|
ZA935110B
(en)
*
|
1992-07-17 |
1994-02-04 |
Smithkline Beecham Corp |
Rapamycin derivatives
|
|
USRE40596E1
(en)
*
|
1993-04-08 |
2008-12-02 |
Novartis Ag |
Rapamycin assay
|
|
GB9307491D0
(en)
*
|
1993-04-08 |
1993-06-02 |
Sandoz Ltd |
Organic compounds
|
|
US7279561B1
(en)
*
|
1993-04-23 |
2007-10-09 |
Wyeth |
Anti-rapamycin monoclonal antibodies
|
|
AU686629B2
(en)
|
1993-04-23 |
1998-02-12 |
Wyeth |
Rapamycin Conjugates and Antibodies
|
|
USRE37421E1
(en)
|
1993-07-16 |
2001-10-23 |
Smithkline Beecham Corporation |
Rapamycin derivatives
|
|
ATE198041T1
(de)
*
|
1993-09-28 |
2000-12-15 |
Scherer Gmbh R P |
Herstellung von weichgelatinekapseln
|
|
US5527907A
(en)
*
|
1993-11-19 |
1996-06-18 |
Abbott Laboratories |
Macrolide immunomodulators
|
|
WO1995014023A1
(en)
*
|
1993-11-19 |
1995-05-26 |
Abbott Laboratories |
Semisynthetic analogs of rapamycin (macrolides) being immunomodulators
|
|
ES2146741T3
(es)
*
|
1993-12-17 |
2000-08-16 |
Novartis Ag |
Derivados de rapamicina utiles como inmunosupresores.
|
|
GB9405350D0
(en)
*
|
1994-03-18 |
1994-05-04 |
Sandoz Ltd |
Organic compounds
|
|
US7205279B2
(en)
*
|
1995-10-25 |
2007-04-17 |
Novartis Ag |
Pharmaceutical compositions
|
|
IL115742A
(en)
|
1994-10-26 |
2000-06-01 |
Novartis Ag |
Pharmaceutical compositions comprising a difficultly soluble active agent a hydrophilic phase a lipophilic phase and a surfactant
|
|
NZ331824A
(en)
*
|
1994-10-26 |
2000-01-28 |
Novartis Ag |
use of an unsaturated fatty alcohol to stabilise a macrolide in a pharmaceutical composition
|
|
US5561138A
(en)
*
|
1994-12-13 |
1996-10-01 |
American Home Products Corporation |
Method of treating anemia
|
|
GB9618952D0
(en)
*
|
1996-09-11 |
1996-10-23 |
Sandoz Ltd |
Process
|
|
US6187757B1
(en)
|
1995-06-07 |
2001-02-13 |
Ariad Pharmaceuticals, Inc. |
Regulation of biological events using novel compounds
|
|
RU2158267C2
(ru)
|
1995-06-09 |
2000-10-27 |
Новартис Аг |
Производные рапамицина и фармацевтическая композиция на их основе
|
|
BE1009856A5
(fr)
*
|
1995-07-14 |
1997-10-07 |
Sandoz Sa |
Composition pharmaceutique sous la forme d'une dispersion solide comprenant un macrolide et un vehicule.
|
|
US5780462A
(en)
*
|
1995-12-27 |
1998-07-14 |
American Home Products Corporation |
Water soluble rapamycin esters
|
|
GB9601120D0
(en)
*
|
1996-01-19 |
1996-03-20 |
Sandoz Ltd |
Organic compounds
|
|
KR100616020B1
(ko)
*
|
1996-03-27 |
2007-01-31 |
노파르티스 아게 |
맥관장애및이종이식술에서의라파마이신유도체의용도
|
|
GB9606452D0
(en)
*
|
1996-03-27 |
1996-06-05 |
Sandoz Ltd |
Organic compounds
|
|
ATE222502T1
(de)
|
1996-07-30 |
2002-09-15 |
Novartis Ag |
Kombinationspräparat mit hemmender wirkung auf die abstossung von transplantaten, autoimmunerkrankungen und entzündungen, welches cyclosporin a und 40-0-(2-hydroxyethyl)-rapamycin enthält
|
|
US5922730A
(en)
*
|
1996-09-09 |
1999-07-13 |
American Home Products Corporation |
Alkylated rapamycin derivatives
|
|
CN1235608A
(zh)
*
|
1996-09-09 |
1999-11-17 |
美国家用产品公司 |
烷基化的雷帕霉素衍生物
|
|
GB9624038D0
(en)
*
|
1996-11-19 |
1997-01-08 |
Sandoz Ltd |
Organic compounds
|
|
US6220537B1
(en)
|
1997-03-07 |
2001-04-24 |
Daiwa Seiko, Inc. |
Fishing spinning reel having smoothly shaped rail portion
|
|
US6306166B1
(en)
*
|
1997-08-13 |
2001-10-23 |
Scimed Life Systems, Inc. |
Loading and release of water-insoluble drugs
|
|
PL342742A1
(en)
*
|
1998-03-06 |
2001-07-02 |
Novartis Ag |
Emulsion-type pre-concentrates containing cyclosporin or macrolyde
|
|
WO1999049863A1
(en)
*
|
1998-03-26 |
1999-10-07 |
Fujisawa Pharmaceutical Co., Ltd. |
Sustained release preparations
|
|
US20050031611A1
(en)
*
|
1998-05-08 |
2005-02-10 |
Beth Israel Deaconess Medical Center |
Transplant tolerance by costimulation blockade and T-cell activation-induced apoptosis
|
|
CN1323310A
(zh)
*
|
1998-08-17 |
2001-11-21 |
美国家用产品公司 |
光致环化的雷帕霉素
|
|
US6015809A
(en)
*
|
1998-08-17 |
2000-01-18 |
American Home Products Corporation |
Photocyclized rapamycin
|
|
GB9826882D0
(en)
|
1998-12-07 |
1999-01-27 |
Novartis Ag |
Organic compounds
|
|
US7276506B2
(en)
*
|
1998-12-28 |
2007-10-02 |
4 Aza Bioscience Nv |
Immunosuppressive effects of pteridine derivatives
|
|
US6946465B2
(en)
*
|
1999-02-02 |
2005-09-20 |
4 Aza Bioscience Nv |
Immunosuppressive effects of pteridine derivatives
|
|
US6318654B1
(en)
|
1999-03-07 |
2001-11-20 |
Daiwa Seiko, Inc. |
Spinning reel for fishing
|
|
US7063857B1
(en)
|
1999-04-30 |
2006-06-20 |
Sucampo Ag |
Use of macrolide compounds for the treatment of dry eye
|
|
ATE474590T1
(de)
|
1999-05-10 |
2010-08-15 |
Paolo Brenner |
Kombination von immunsuppressiven substanzen zur behandlung oder vorbeugung von transplantat abstossungen
|
|
USD440626S1
(en)
|
1999-06-08 |
2001-04-17 |
Daiwa Seiko, Inc. |
Line slider for a spinning fishing reel
|
|
ES2222222T3
(es)
*
|
1999-08-18 |
2005-02-01 |
Wyeth |
Esteres hidrosolubles de sdz-rad.
|
|
US6331547B1
(en)
|
1999-08-18 |
2001-12-18 |
American Home Products Corporation |
Water soluble SDZ RAD esters
|
|
US7067526B1
(en)
|
1999-08-24 |
2006-06-27 |
Ariad Gene Therapeutics, Inc. |
28-epirapalogs
|
|
AU783158B2
(en)
|
1999-08-24 |
2005-09-29 |
Ariad Pharmaceuticals, Inc. |
28-epirapalogs
|
|
US20070032853A1
(en)
*
|
2002-03-27 |
2007-02-08 |
Hossainy Syed F |
40-O-(2-hydroxy)ethyl-rapamycin coated stent
|
|
US6790228B2
(en)
|
1999-12-23 |
2004-09-14 |
Advanced Cardiovascular Systems, Inc. |
Coating for implantable devices and a method of forming the same
|
|
US7807211B2
(en)
|
1999-09-03 |
2010-10-05 |
Advanced Cardiovascular Systems, Inc. |
Thermal treatment of an implantable medical device
|
|
US6277983B1
(en)
|
2000-09-27 |
2001-08-21 |
American Home Products Corporation |
Regioselective synthesis of rapamycin derivatives
|
|
RU2264405C2
(ru)
*
|
1999-12-06 |
2005-11-20 |
Новартис Аг |
40-o-(2-гидрокси)этилрапамицин в кристаллической несольватированной форме, фармацевтическая композиция, содержащая такой макролид в качестве действующего вещества, и способ его получения
|
|
ATE475418T1
(de)
|
2000-01-14 |
2010-08-15 |
Univ Pennsylvania |
O-methylierte rapamycinderivate zur milderung oder vermeidung lymphoproliferativer erkrankungen
|
|
GB0008785D0
(en)
|
2000-04-10 |
2000-05-31 |
Novartis Ag |
Organic compounds
|
|
US8236048B2
(en)
|
2000-05-12 |
2012-08-07 |
Cordis Corporation |
Drug/drug delivery systems for the prevention and treatment of vascular disease
|
|
US6670355B2
(en)
|
2000-06-16 |
2003-12-30 |
Wyeth |
Method of treating cardiovascular disease
|
|
PT1318837E
(pt)
|
2000-08-11 |
2004-12-31 |
Wyeth Corp |
Metodo de tratamenton de carcinoma positivo a receptor de estrogenio
|
|
CA2421485A1
(en)
|
2000-09-19 |
2002-03-28 |
Wyeth |
Water soluble rapamycin esters
|
|
US6399625B1
(en)
*
|
2000-09-27 |
2002-06-04 |
Wyeth |
1-oxorapamycins
|
|
DE60124285T3
(de)
|
2000-09-29 |
2011-03-17 |
Cordis Corp., Miami Lakes |
Beschichtete medizinische geräte
|
|
US6440991B1
(en)
|
2000-10-02 |
2002-08-27 |
Wyeth |
Ethers of 7-desmethlrapamycin
|
|
US6399626B1
(en)
|
2000-10-02 |
2002-06-04 |
Wyeth |
Hydroxyesters of 7-desmethylrapamycin
|
|
MX242553B
(es)
|
2000-10-20 |
2006-12-06 |
Eisai Co Ltd |
Derivados aromaticos que contienen nitrogeno.
|
|
US7754208B2
(en)
|
2001-01-17 |
2010-07-13 |
Trubion Pharmaceuticals, Inc. |
Binding domain-immunoglobulin fusion proteins
|
|
EP2762140B1
(en)
*
|
2001-02-19 |
2017-03-22 |
Novartis AG |
Treatment of solid brain tumours with a rapamycin derivative
|
|
AU2016206379B2
(en)
*
|
2001-02-19 |
2017-09-14 |
Novartis Ag |
Cancer Treatment
|
|
AU2011226833B9
(en)
*
|
2001-02-19 |
2014-07-03 |
Novartis Ag |
Cancer treatment
|
|
AU2005201004A1
(en)
*
|
2001-02-19 |
2005-03-24 |
Novartis Ag |
Cancer treatment
|
|
TWI296196B
(en)
*
|
2001-04-06 |
2008-05-01 |
Wyeth Corp |
Antineoplastic combinations
|
|
TWI233359B
(en)
*
|
2001-04-06 |
2005-06-01 |
Wyeth Corp |
Pharmaceutical composition for treating neoplasm
|
|
US6613083B2
(en)
|
2001-05-02 |
2003-09-02 |
Eckhard Alt |
Stent device and method
|
|
KR20040019034A
(ko)
|
2001-07-06 |
2004-03-04 |
수캄포 아게 |
인터루킨 2 억제제 및 항미생물제를 포함하는 국소 투여용조성물
|
|
WO2003009815A2
(en)
|
2001-07-25 |
2003-02-06 |
Biomarin Pharmaceutical Inc. |
Compositions and methods for modulating blood-brain barrier transport
|
|
US6939376B2
(en)
*
|
2001-11-05 |
2005-09-06 |
Sun Biomedical, Ltd. |
Drug-delivery endovascular stent and method for treating restenosis
|
|
US7682387B2
(en)
|
2002-04-24 |
2010-03-23 |
Biosensors International Group, Ltd. |
Drug-delivery endovascular stent and method for treating restenosis
|
|
WO2003043650A1
(en)
*
|
2001-11-21 |
2003-05-30 |
Sucampo Ag |
Use of fk506 and analogues for treating allergic diseases
|
|
WO2003064383A2
(en)
|
2002-02-01 |
2003-08-07 |
Ariad Gene Therapeutics, Inc. |
Phosphorus-containing compounds & uses thereof
|
|
US20030176455A1
(en)
*
|
2002-03-13 |
2003-09-18 |
Wyeth |
Method of inhibiting cell death
|
|
US20040024450A1
(en)
*
|
2002-04-24 |
2004-02-05 |
Sun Biomedical, Ltd. |
Drug-delivery endovascular stent and method for treating restenosis
|
|
BR0311173A
(pt)
|
2002-05-16 |
2005-03-15 |
Novartis Ag |
Uso de agentes de ligação do receptor de edg em câncer
|
|
DK1589031T3
(da)
|
2002-07-16 |
2007-12-10 |
Biotica Tech Ltd |
Fremstillingaf polyketider og andre naturlige produkter
|
|
ES2300622T3
(es)
|
2002-07-30 |
2008-06-16 |
Wyeth |
Formulaciones parenterales que contienen un hidroxiester de rapamicina.
|
|
AU2003272471B2
(en)
|
2002-09-18 |
2010-10-07 |
Trustees Of The University Of Pennsylvania |
Method of inhibiting choroidal neovascularization
|
|
RU2391094C2
(ru)
|
2002-09-24 |
2010-06-10 |
Новартис Аг |
Применение агониста рецептора s1p и способ лечения, облегчения или задержки прогрессирования неврита зрительного нерва или демиелинизационных заболеваний
|
|
AU2003293529A1
(en)
|
2002-12-16 |
2004-07-29 |
Nitromed, Inc. |
Nitrosated and nitrosylated rapamycin compounds, compositions and methods of use
|
|
ATE457716T1
(de)
|
2002-12-30 |
2010-03-15 |
Angiotech Int Ag |
Wirkstofffreisetzung von schnell gelierender polymerzusammensetzung
|
|
AR042938A1
(es)
*
|
2003-02-06 |
2005-07-06 |
Wyeth Corp |
Uso del cci-779 en el tratamiento de la fibrosis hepatica
|
|
US20090093875A1
(en)
|
2007-05-01 |
2009-04-09 |
Abbott Laboratories |
Drug eluting stents with prolonged local elution profiles with high local concentrations and low systemic concentrations
|
|
AR043504A1
(es)
*
|
2003-03-17 |
2005-08-03 |
Novartis Ag |
Composiciones farmaceuticas que comprenden rapamicina para el tratamiento de enfermedades inflamatorias
|
|
GB0307867D0
(en)
*
|
2003-04-04 |
2003-05-14 |
Novartis Ag |
Pharmaceutical composition
|
|
WO2004089369A2
(en)
*
|
2003-04-11 |
2004-10-21 |
Cambridge University Technical Services Limited |
Methods and means for treating protein conformational disorders
|
|
PT1615640E
(pt)
*
|
2003-04-22 |
2007-04-30 |
Wyeth Corp |
Combinações antineoplásticas
|
|
RU2233285C1
(ru)
*
|
2003-05-15 |
2004-07-27 |
Институт молекулярной генетики РАН |
Высокомеченный тритием [3h]-рапамицин
|
|
US7160867B2
(en)
|
2003-05-16 |
2007-01-09 |
Isotechnika, Inc. |
Rapamycin carbohydrate derivatives
|
|
US20050118344A1
(en)
|
2003-12-01 |
2005-06-02 |
Pacetti Stephen D. |
Temperature controlled crimping
|
|
ATE414089T1
(de)
*
|
2003-07-08 |
2008-11-15 |
Novartis Ag |
Verwendung von rapamycin und dessen derivaten zur behandlung von knochenverlust
|
|
DE602004008304T2
(de)
*
|
2003-09-12 |
2008-05-08 |
4 Aza Ip Nv |
Pteridin-derivate zur behandlung von erkrankungen im zusammenhang mit tnf-alpha
|
|
JP2007505932A
(ja)
|
2003-09-18 |
2007-03-15 |
マクサイト， インコーポレイテッド |
経強膜送達
|
|
US20070032477A1
(en)
*
|
2003-10-17 |
2007-02-08 |
Waer Mark J A |
Pteridine derivatives useful for making pharmaceutical compositions
|
|
US7220755B2
(en)
|
2003-11-12 |
2007-05-22 |
Biosensors International Group, Ltd. |
42-O-alkoxyalkyl rapamycin derivatives and compositions comprising same
|
|
US9114198B2
(en)
|
2003-11-19 |
2015-08-25 |
Advanced Cardiovascular Systems, Inc. |
Biologically beneficial coatings for implantable devices containing fluorinated polymers and methods for fabricating the same
|
|
GB0327840D0
(en)
*
|
2003-12-01 |
2003-12-31 |
Novartis Ag |
Organic compounds
|
|
DE602005011879D1
(de)
|
2004-03-01 |
2009-02-05 |
Terumo Corp |
Verfahren zur Herstellung von O-alkylierten Rapamycinderivaten
|
|
JP4540704B2
(ja)
|
2004-03-10 |
2010-09-08 |
セラディン インコーポレイテッド |
エベロリムスの測定方法および測定キット
|
|
AR047988A1
(es)
*
|
2004-03-11 |
2006-03-15 |
Wyeth Corp |
Combinaciones antineoplásicas de cci-779 y rituximab
|
|
US8551512B2
(en)
*
|
2004-03-22 |
2013-10-08 |
Advanced Cardiovascular Systems, Inc. |
Polyethylene glycol/poly(butylene terephthalate) copolymer coated devices including EVEROLIMUS
|
|
US8778014B1
(en)
|
2004-03-31 |
2014-07-15 |
Advanced Cardiovascular Systems, Inc. |
Coatings for preventing balloon damage to polymer coated stents
|
|
JP2007532655A
(ja)
*
|
2004-04-14 |
2007-11-15 |
ワイス |
ラパマイシンコンジュゲートおよび抗体のための前駆体である、ジカルボン酸とのラパマイシン４２−エステルおよびジカルボン酸とのｆｋ−５０６３２−エステルの調製プロセス
|
|
JP2007534337A
(ja)
*
|
2004-04-27 |
2007-11-29 |
ワイス |
ラパマイシン特異的メチラーゼを用いるラパマイシンの標識
|
|
EP2583678A3
(en)
|
2004-06-24 |
2013-11-13 |
Novartis Vaccines and Diagnostics, Inc. |
Small molecule immunopotentiators and assays for their detection
|
|
US8709469B2
(en)
|
2004-06-30 |
2014-04-29 |
Abbott Cardiovascular Systems Inc. |
Anti-proliferative and anti-inflammatory agent combination for treatment of vascular disorders with an implantable medical device
|
|
GB0417852D0
(en)
|
2004-08-11 |
2004-09-15 |
Biotica Tech Ltd |
Production of polyketides and other natural products
|
|
EP1781672B1
(en)
|
2004-08-27 |
2010-10-06 |
Cordis Corporation |
Solvent free amorphous rapamycin
|
|
WO2006030826A1
(ja)
|
2004-09-17 |
2006-03-23 |
Eisai R & D Management Co., Ltd. |
医薬組成物
|
|
US7901451B2
(en)
|
2004-09-24 |
2011-03-08 |
Biosensors International Group, Ltd. |
Drug-delivery endovascular stent and method for treating restenosis
|
|
US8313763B2
(en)
|
2004-10-04 |
2012-11-20 |
Tolmar Therapeutics, Inc. |
Sustained delivery formulations of rapamycin compounds
|
|
JP2008520547A
(ja)
*
|
2004-10-04 |
2008-06-19 |
キューエルティー ユーエスエー，インコーポレイテッド． |
眼部送達のためのポリマー送達処方
|
|
RU2007112787A
(ru)
*
|
2004-10-28 |
2008-12-10 |
Вайет (Us) |
ПРИМЕНЕНИЕ ИНГИБИТОРА mTOR ПРИ ЛЕЧЕНИИ ЛЕЙОМИОМЫ МАТКИ
|
|
US8021849B2
(en)
|
2004-11-05 |
2011-09-20 |
Siemens Healthcare Diagnostics Inc. |
Methods and kits for the determination of sirolimus in a sample
|
|
WO2006053754A1
(en)
*
|
2004-11-19 |
2006-05-26 |
Novartis Ag |
COMBINATIONS OF ANTI-ATHEROSCLEROTIC PEPTIDES AND AN mTOR INHIBITING AGENT AND THEIR METHODS OF USE
|
|
US20060160837A1
(en)
*
|
2004-12-29 |
2006-07-20 |
The Brigham And Women's Hospital, Inc. |
Rapamycin compounds in the treatment of neurofibromatosis type 1
|
|
AU2006213673A1
(en)
|
2005-02-09 |
2006-08-17 |
Santen Pharmaceutical Co., Ltd. |
Formulations for ocular treatment
|
|
US8663639B2
(en)
|
2005-02-09 |
2014-03-04 |
Santen Pharmaceutical Co., Ltd. |
Formulations for treating ocular diseases and conditions
|
|
GB0503936D0
(en)
*
|
2005-02-25 |
2005-04-06 |
San Raffaele Centro Fond |
Method
|
|
GB0504544D0
(en)
|
2005-03-04 |
2005-04-13 |
Novartis Ag |
Organic compounds
|
|
BRPI0608885A2
(pt)
|
2005-03-07 |
2017-02-21 |
Wyeth Corp |
composto de isômero c de sdz-rad, composição farmacêutica, e, embalagem farmacêutica
|
|
AU2006221774A1
(en)
|
2005-03-11 |
2006-09-14 |
Biotica Technology Limited |
Medical uses of 39-desmethoxyrapamycin and analogues thereof
|
|
GB0504994D0
(en)
*
|
2005-03-11 |
2005-04-20 |
Biotica Tech Ltd |
Novel compounds
|
|
US20100061994A1
(en)
*
|
2005-03-11 |
2010-03-11 |
Rose Mary Sheridan |
Medical uses of 39-desmethoxyrapamycin and analogues thereof
|
|
GT200600148A
(es)
*
|
2005-04-14 |
2006-11-22 |
|
Metodos para el tratamiento y la prevencion de fibrosis
|
|
US7189582B2
(en)
*
|
2005-04-27 |
2007-03-13 |
Dade Behring Inc. |
Compositions and methods for detection of sirolimus
|
|
US8847766B2
(en)
|
2005-04-28 |
2014-09-30 |
Proteus Digital Health, Inc. |
Pharma-informatics system
|
|
MX2007015083A
(es)
*
|
2005-05-31 |
2008-01-17 |
Novartis Ag |
Combinacion de inhibidores de hmg-coa-reductasa e inhibidores de mtor.
|
|
US20070004767A1
(en)
*
|
2005-06-30 |
2007-01-04 |
Gutmann David H |
Methods for treating neurofibromatosis 1
|
|
JP5756588B2
(ja)
|
2005-07-15 |
2015-07-29 |
ミセル テクノロジーズ、インコーポレイテッド |
制御されたモルホロジーの薬剤粉末を含むポリマーコーティング
|
|
WO2007011708A2
(en)
|
2005-07-15 |
2007-01-25 |
Micell Technologies, Inc. |
Stent with polymer coating containing amorphous rapamycin
|
|
KR20130087058A
(ko)
|
2005-07-20 |
2013-08-05 |
노파르티스 아게 |
피리미딜아미노벤즈아미드와 ｍｔｏｒ 키나제 억제제의 조합물
|
|
SG10201403526YA
(en)
|
2005-07-25 |
2014-10-30 |
Emergent Product Dev Seattle |
B-cell reduction using cd37-specific and cd20-specific binding molecules
|
|
EP2281901B1
(en)
|
2005-08-02 |
2013-11-27 |
Eisai R&D Management Co., Ltd. |
Anti-tumour pharmaceutical composition with angiogenesis inhibitors
|
|
JP5164167B2
(ja)
|
2005-08-30 |
2013-03-13 |
ユニバーシティー オブ マイアミ |
免疫調節性腫瘍壊死因子受容体２５（ｔｎｆｒ２５）のアゴニスト、アンタゴニスト及び免疫毒素
|
|
EP1776970A1
(en)
|
2005-10-12 |
2007-04-25 |
Albert Schömig |
Implant with multiple coating
|
|
CA2626326C
(en)
|
2005-11-04 |
2021-02-16 |
Wyeth |
Antineoplastic combinations with mtor inhibitor, herceptin, and/or hki-272
|
|
GB0523659D0
(en)
*
|
2005-11-21 |
2005-12-28 |
Novartis Ag |
Organic compounds
|
|
EP1962819A1
(en)
*
|
2005-12-20 |
2008-09-03 |
Wyeth |
Control of cci-779 dosage form stability through control of drug substance impurities
|
|
AU2007204410A1
(en)
*
|
2006-01-12 |
2007-07-19 |
Novartis Ag |
Combination of mTOR inhibitor and antipolate compound
|
|
US20070173923A1
(en)
*
|
2006-01-20 |
2007-07-26 |
Savage Douglas R |
Drug reservoir stent
|
|
GB0601406D0
(en)
*
|
2006-01-24 |
2006-03-08 |
Novartis Ag |
Organic Compounds
|
|
PT1983984T
(pt)
|
2006-02-02 |
2018-06-14 |
Novartis Ag |
Tratamento da esclerosa tuberosa
|
|
BRPI0707612B8
(pt)
|
2006-02-09 |
2021-05-25 |
Macusight Inc |
vaso lacrado e formulações líquidas contidas no mesmo
|
|
US7622477B2
(en)
|
2006-02-28 |
2009-11-24 |
Cordis Corporation |
Isomers and 42-epimers of rapamycin alkyl ether analogs, methods of making and using the same
|
|
US7678901B2
(en)
*
|
2006-02-28 |
2010-03-16 |
Wyeth |
Rapamycin analogs containing an antioxidant moiety
|
|
US7605257B2
(en)
*
|
2006-03-07 |
2009-10-20 |
Wyeth |
Processes for preparing water-soluble polyethylene glycol conjugates of macrolide immunosuppressants
|
|
US8222271B2
(en)
|
2006-03-23 |
2012-07-17 |
Santen Pharmaceutical Co., Ltd. |
Formulations and methods for vascular permeability-related diseases or conditions
|
|
CA2996768C
(en)
|
2006-04-26 |
2020-12-08 |
Micell Technologies, Inc. |
Coatings containing multiple drugs
|
|
AU2007252506C1
(en)
|
2006-05-18 |
2012-07-19 |
Eisai R & D Management Co., Ltd. |
Antitumor agent for thyroid cancer
|
|
GB0609963D0
(en)
*
|
2006-05-19 |
2006-06-28 |
Biotica Tech Ltd |
Novel compounds
|
|
GB0609962D0
(en)
*
|
2006-05-19 |
2006-06-28 |
Biotica Tech Ltd |
Novel compounds
|
|
US8962697B2
(en)
*
|
2006-06-30 |
2015-02-24 |
Interface Biologics Inc. |
Bioreponsive polymers
|
|
WO2008009078A2
(en)
|
2006-07-20 |
2008-01-24 |
Gilead Sciences, Inc. |
4,6-dl- and 2,4,6-trisubstituted quinazoline derivatives useful for treating viral infections
|
|
US10144736B2
(en)
*
|
2006-07-20 |
2018-12-04 |
Gilead Sciences, Inc. |
Substituted pteridines useful for the treatment and prevention of viral infections
|
|
WO2008016633A2
(en)
*
|
2006-08-02 |
2008-02-07 |
Ariad Gene Therapeutics, Inc. |
Combination therapy
|
|
EP2065372B1
(en)
|
2006-08-28 |
2012-11-28 |
Eisai R&D Management Co., Ltd. |
Antitumor agent for undifferentiated gastric cancer
|
|
US20080051691A1
(en)
*
|
2006-08-28 |
2008-02-28 |
Wyeth |
Implantable shunt or catheter enabling gradual delivery of therapeutic agents
|
|
US10695327B2
(en)
|
2006-09-13 |
2020-06-30 |
Elixir Medical Corporation |
Macrocyclic lactone compounds and methods for their use
|
|
CN101557814B
(zh)
*
|
2006-09-13 |
2015-05-20 |
万能医药公司 |
大环内酯化合物及它们的使用方法
|
|
US8088789B2
(en)
|
2006-09-13 |
2012-01-03 |
Elixir Medical Corporation |
Macrocyclic lactone compounds and methods for their use
|
|
JP2010503710A
(ja)
|
2006-09-18 |
2010-02-04 |
ラプトール ファーマシューティカル インコーポレイテッド |
受容体関連タンパク質（ｒａｐ）結合体の投与による肝障害の処置
|
|
US20080097591A1
(en)
|
2006-10-20 |
2008-04-24 |
Biosensors International Group |
Drug-delivery endovascular stent and method of use
|
|
US8067055B2
(en)
*
|
2006-10-20 |
2011-11-29 |
Biosensors International Group, Ltd. |
Drug-delivery endovascular stent and method of use
|
|
WO2008065887A1
(en)
|
2006-11-27 |
2008-06-05 |
Terumo Kabushiki Kaisha |
Process for producing o-alkylated rapamycin derivative, and o-alkylated rapamycin derivative
|
|
JP5603598B2
(ja)
|
2007-01-08 |
2014-10-08 |
ミセル テクノロジーズ、インコーポレイテッド |
生物分解層を有するステント
|
|
US11426494B2
(en)
|
2007-01-08 |
2022-08-30 |
MT Acquisition Holdings LLC |
Stents having biodegradable layers
|
|
KR20120106880A
(ko)
|
2007-01-21 |
2012-09-26 |
헤모텍 아게 |
체강의 협착 치료 및 급성 재협착 예방을 위한 의료 제품
|
|
CN101600694A
(zh)
|
2007-01-29 |
2009-12-09 |
卫材R&D管理有限公司 |
未分化型胃癌治疗用组合物
|
|
TW200845960A
(en)
*
|
2007-04-05 |
2008-12-01 |
Wyeth Corp |
Wortmannin-rapalog conjugate and uses thereof
|
|
TW200901989A
(en)
|
2007-04-10 |
2009-01-16 |
Wyeth Corp |
Anti-tumor activity of CCI-779 in papillary renal cell cancer
|
|
US9433516B2
(en)
|
2007-04-17 |
2016-09-06 |
Micell Technologies, Inc. |
Stents having controlled elution
|
|
US9192697B2
(en)
|
2007-07-03 |
2015-11-24 |
Hemoteq Ag |
Balloon catheter for treating stenosis of body passages and for preventing threatening restenosis
|
|
WO2009043174A1
(en)
|
2007-10-05 |
2009-04-09 |
Interface Biologics Inc. |
Oligofluorinated cross-linked polymers and uses thereof
|
|
EP2214748B1
(en)
|
2007-10-19 |
2016-12-07 |
Interface Biologics Inc. |
Self-eliminating coatings
|
|
AU2008325608B2
(en)
|
2007-11-09 |
2013-03-14 |
Eisai R & D Management Co., Ltd. |
Combination of anti-angiogenic substance and anti-tumor platinum complex
|
|
CN103480047B
(zh)
|
2007-11-14 |
2015-02-18 |
生物传感器国际集团有限公司 |
自动化涂覆设备和方法
|
|
US8921642B2
(en)
*
|
2008-01-11 |
2014-12-30 |
Massachusetts Eye And Ear Infirmary |
Conditional-stop dimerizable caspase transgenic animals
|
|
WO2009114010A1
(en)
*
|
2008-03-11 |
2009-09-17 |
Elixir Medical Corporation |
Macrocyclic lactone compounds and methods for their use
|
|
US20100048913A1
(en)
|
2008-03-14 |
2010-02-25 |
Angela Brodie |
Novel C-17-Heteroaryl Steroidal CYP17 Inhibitors/Antiandrogens;Synthesis In Vitro Biological Activities, Pharmacokinetics and Antitumor Activity
|
|
AU2009225434B2
(en)
|
2008-03-21 |
2014-05-22 |
The University Of Chicago |
Treatment with opioid antagonists and mTOR inhibitors
|
|
ES2368700T3
(es)
|
2008-04-11 |
2011-11-21 |
Emergent Product Development Seattle, Llc |
Agente inmunoterapéutico para cd37 y combinación con un agente quimioterapéutico bifuncional del mismo.
|
|
WO2009131631A1
(en)
*
|
2008-04-14 |
2009-10-29 |
Poniard Pharmaceuticals, Inc. |
Rapamycin analogs as anti-cancer agents
|
|
BRPI0910969B8
(pt)
|
2008-04-17 |
2021-06-22 |
Micell Technologies Inc |
dispositivo
|
|
KR20110020928A
(ko)
|
2008-06-20 |
2011-03-03 |
노파르티스 아게 |
다발성 경화증을 치료하기 위한 소아용 조성물
|
|
US8765162B2
(en)
|
2008-06-30 |
2014-07-01 |
Abbott Cardiovascular Systems Inc. |
Poly(amide) and poly(ester-amide) polymers and drug delivery particles and coatings containing same
|
|
EP2313122B1
(en)
|
2008-07-17 |
2019-03-06 |
Micell Technologies, Inc. |
Drug delivery medical device
|
|
WO2011009096A1
(en)
|
2009-07-16 |
2011-01-20 |
Micell Technologies, Inc. |
Drug delivery medical device
|
|
US8092822B2
(en)
|
2008-09-29 |
2012-01-10 |
Abbott Cardiovascular Systems Inc. |
Coatings including dexamethasone derivatives and analogs and olimus drugs
|
|
US20100086579A1
(en)
*
|
2008-10-03 |
2010-04-08 |
Elixir Medical Corporation |
Macrocyclic lactone compounds and methods for their use
|
|
BRPI0920246A2
(pt)
|
2008-10-17 |
2017-06-27 |
Winconsin Alumni Res Foundation |
método de preparação de alfa-beta peptídios biologicamente ativos.
|
|
CN102292078A
(zh)
|
2008-11-11 |
2011-12-21 |
得克萨斯大学体系董事会 |
哺乳动物雷帕霉素靶蛋白的抑制
|
|
AU2009329917B2
(en)
|
2008-12-23 |
2016-03-31 |
Gilead Pharmasset Llc |
Nucleoside analogs
|
|
BRPI0923815A2
(pt)
|
2008-12-23 |
2015-07-14 |
Pharmasset Inc |
Síntese de nucleosídeos de purina
|
|
CN102695513A
(zh)
|
2008-12-23 |
2012-09-26 |
吉利德制药有限责任公司 |
核苷氨基磷酸酯
|
|
JP5643770B2
(ja)
*
|
2009-01-21 |
2014-12-17 |
バイオコン・リミテッドＢｉｏｃｏｎ Ｌｉｍｉｔｅｄ |
シロリムスの安定性の決定方法およびその安定形態の調製方法
|
|
EP2393827B1
(en)
|
2009-02-05 |
2015-10-07 |
Tokai Pharmaceuticals, Inc. |
Novel prodrugs of steroidal cyp17 inhibitors/antiandrogens
|
|
ES2543216T3
(es)
|
2009-03-13 |
2015-08-17 |
Katholieke Universiteit Leuven, K.U. Leuven R&D |
Moduladores de tiazolopirimidina como agentes inmunosupresores
|
|
EP2413847A4
(en)
|
2009-04-01 |
2013-11-27 |
Micell Technologies Inc |
COATED STENTS
|
|
AU2010236825A1
(en)
|
2009-04-16 |
2011-09-15 |
Merck Sharp & Dohme Corp. |
Compositions and methods for treating cancer
|
|
BRPI1011188B1
(pt)
|
2009-05-06 |
2019-10-15 |
Laboratory Skin Care, Inc. |
Composições de liberação dérmica compreendendo complexos de partículas de agente ativo-fosfato de cálcio e métodos para usar as mesmas
|
|
EP2451496B1
(en)
|
2009-07-10 |
2015-07-22 |
Boston Scientific Scimed, Inc. |
Use of nanocrystals for a drug delivery balloon
|
|
WO2011008393A2
(en)
|
2009-07-17 |
2011-01-20 |
Boston Scientific Scimed, Inc. |
Nucleation of drug delivery balloons to provide improved crystal size and density
|
|
DK2462165T3
(en)
|
2009-08-03 |
2016-08-29 |
Univ Miami |
Method for in vivo proliferation of regulatory T cells
|
|
EA020151B1
(ru)
|
2009-10-23 |
2014-09-30 |
Эли Лилли Энд Компани |
Ингибиторы akt и фармацевтические составы, их содержащие
|
|
JP2013509444A
(ja)
|
2009-10-30 |
2013-03-14 |
アリアド・ファーマシューティカルズ・インコーポレイテッド |
がんの治療方法及び治療用組成物
|
|
US9283211B1
(en)
|
2009-11-11 |
2016-03-15 |
Rapamycin Holdings, Llc |
Oral rapamycin preparation and use for stomatitis
|
|
WO2015161139A1
(en)
|
2014-04-16 |
2015-10-22 |
Rapamycin Holdings, Llc |
Oral rapamycin preparation and use for stomatitis
|
|
US20120232087A1
(en)
|
2009-11-18 |
2012-09-13 |
Silvia Buonamici |
Methods and compositions for treating solid tumors and other malignancies
|
|
US8900603B2
(en)
|
2009-12-18 |
2014-12-02 |
Interface Biologics, Inc. |
Local delivery of drugs from self assembled coatings
|
|
CN102127092B
(zh)
*
|
2010-01-18 |
2013-04-17 |
东南大学 |
依维莫斯的制备
|
|
EP2531140B1
(en)
|
2010-02-02 |
2017-11-01 |
Micell Technologies, Inc. |
Stent and stent delivery system with improved deliverability
|
|
CA2792258A1
(en)
|
2010-03-05 |
2011-09-09 |
President And Fellows Of Harvard College |
Induced dendritic cell compositions and uses thereof
|
|
SMT201700412T1
(it)
|
2010-03-31 |
2017-11-15 |
Gilead Pharmasset Llc |
Procedimento per la cristallizzazione di (s)-isopropil 2-(((s)-(perfluorofenossi)(fenossi)fosforil)ammino)propanoato
|
|
EP2558092B1
(en)
|
2010-04-13 |
2018-06-27 |
Novartis AG |
Combination comprising a cyclin dependent kinase 4 or cyclin dependent kinase 6 (cdk4/6) inhibitor and an mtor inhibitor for treating cancer
|
|
WO2011128405A1
(en)
|
2010-04-16 |
2011-10-20 |
Novartis Ag |
Combination of organic compounds
|
|
WO2011133655A1
(en)
|
2010-04-22 |
2011-10-27 |
Micell Technologies, Inc. |
Stents and other devices having extracellular matrix coating
|
|
CA2795544A1
(en)
|
2010-04-27 |
2011-11-03 |
Roche Glycart Ag |
Combination therapy of an afucosylated cd20 antibody with a mtor inhibitor
|
|
GB201012889D0
(en)
|
2010-08-02 |
2010-09-15 |
Univ Leuven Kath |
Antiviral activity of novel bicyclic heterocycles
|
|
KR101677790B1
(ko)
|
2010-06-25 |
2016-11-18 |
에자이 알앤드디 매니지먼트 가부시키가이샤 |
키나제 저해 작용을 갖는 화합물의 병용에 의한 항종양제
|
|
EP2593039B1
(en)
|
2010-07-16 |
2022-11-30 |
Micell Technologies, Inc. |
Drug delivery medical device
|
|
WO2012031236A1
(en)
|
2010-09-02 |
2012-03-08 |
Boston Scientific Scimed, Inc. |
Coating process for drug delivery balloons using heat-induced rewrap memory
|
|
GB201015411D0
(en)
|
2010-09-15 |
2010-10-27 |
Univ Leuven Kath |
Anti-cancer activity of novel bicyclic heterocycles
|
|
US20120077778A1
(en)
|
2010-09-29 |
2012-03-29 |
Andrea Bourdelais |
Ladder-Frame Polyether Conjugates
|
|
CN102464669B
(zh)
*
|
2010-11-17 |
2014-04-16 |
浙江海正药业股份有限公司 |
无定形依维莫司及其制备方法
|
|
EP2640730B1
(en)
*
|
2010-11-19 |
2019-08-07 |
Biocon Limited |
Processes for preparation of everolimus and intermediates thereof
|
|
EP4230631A3
(en)
|
2011-02-04 |
2024-03-27 |
Synthon B.V. |
Process for making trisubstituted silyloxyethyl triflates
|
|
EP2675451B9
(en)
|
2011-02-18 |
2017-07-26 |
Novartis Pharma AG |
mTOR/JAK INHIBITOR COMBINATION THERAPY
|
|
CN102174053B
(zh)
*
|
2011-03-09 |
2014-04-16 |
成都雅途生物技术有限公司 |
依维莫司的纯化方法
|
|
PL2683406T3
(pl)
|
2011-03-11 |
2019-11-29 |
Beth Israel Deaconess Medical Ct Inc |
Przeciwciała anty-cd40 i ich zastosowania
|
|
EP2508525A1
(en)
|
2011-04-05 |
2012-10-10 |
Bayer Pharma Aktiengesellschaft |
Substituted 2,3-dihydroimidazo[1,2-c]quinazoline salts
|
|
KR101762999B1
(ko)
|
2011-04-18 |
2017-07-28 |
에자이 알앤드디 매니지먼트 가부시키가이샤 |
종양 치료제
|
|
JP2014519813A
(ja)
|
2011-04-25 |
2014-08-21 |
オーエスアイ・ファーマシューティカルズ，エルエルシー |
癌薬剤発見、診断、および治療におけるｅｍｔ遺伝子シグネチャーの使用
|
|
PH12013502077A1
(en)
|
2011-04-25 |
2013-12-16 |
Novartis Ag |
Combination of a phosphatidylinositol-3-kinase (pi3k) inhibitor and a mtor inhibitor
|
|
US9945862B2
(en)
|
2011-06-03 |
2018-04-17 |
Eisai R&D Management Co., Ltd. |
Biomarkers for predicting and assessing responsiveness of thyroid and kidney cancer subjects to lenvatinib compounds
|
|
US8809562B2
(en)
|
2011-06-06 |
2014-08-19 |
Chevron Phillips Chemical Company Lp |
Use of metallocene compounds for cancer treatment
|
|
EP2532740A1
(en)
|
2011-06-11 |
2012-12-12 |
Michael Schmück |
Antigen-specific CD4+ and CD8+ central-memory T cell preparations for adoptive T cell therapy
|
|
WO2013012689A1
(en)
|
2011-07-15 |
2013-01-24 |
Micell Technologies, Inc. |
Drug delivery medical device
|
|
WO2013013708A1
(en)
|
2011-07-26 |
2013-01-31 |
Fundació Institut D'investigació Biomèdica De Bellvitge |
Treatment of acute rejection in renal transplant
|
|
US20130028895A1
(en)
|
2011-07-27 |
2013-01-31 |
Gerald Wulf |
Exosome inhibiting agents and uses thereof
|
|
US8669360B2
(en)
|
2011-08-05 |
2014-03-11 |
Boston Scientific Scimed, Inc. |
Methods of converting amorphous drug substance into crystalline form
|
|
US9056152B2
(en)
|
2011-08-25 |
2015-06-16 |
Boston Scientific Scimed, Inc. |
Medical device with crystalline drug coating
|
|
CN102268015B
(zh)
*
|
2011-08-30 |
2013-08-28 |
成都摩尔生物医药有限公司 |
一种依维莫司的合成方法
|
|
GB201115665D0
(en)
|
2011-09-09 |
2011-10-26 |
Univ Leuven Kath |
Autoimmune and inflammatory disorder therapy
|
|
PE20141649A1
(es)
|
2011-10-06 |
2014-11-14 |
Novartis Ag |
Composiciones farmaceuticas que comprenden 40-o-(2-hidroxi)etil-rapamicina
|
|
US10188772B2
(en)
|
2011-10-18 |
2019-01-29 |
Micell Technologies, Inc. |
Drug delivery medical device
|
|
EP2589383A1
(en)
|
2011-11-06 |
2013-05-08 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Berlin |
FKBP subtype-specific rapamycin analogue for use in treatment of diseases
|
|
GB201122305D0
(en)
|
2011-12-23 |
2012-02-01 |
Biotica Tech Ltd |
Novel compound
|
|
BR112014028881A2
(pt)
|
2012-05-23 |
2017-06-27 |
Hoffmann La Roche |
populações de células, banco de células, métodos de obtenção de uma população de células, métodos de identificação de um fator, métodos de seleção, métodos de fornecimento de terapia, populações de hepatócitos e método de obtenção de células
|
|
CN102786534A
(zh)
*
|
2012-05-25 |
2012-11-21 |
上海现代制药股份有限公司 |
一种依维莫司的制备方法
|
|
AU2013270798B2
(en)
|
2012-06-08 |
2017-09-07 |
Biotronik Ag |
Rapamycin 40-O-cyclic hydrocarbon esters, compositions and methods
|
|
WO2013192367A1
(en)
|
2012-06-22 |
2013-12-27 |
Novartis Ag |
Neuroendocrine tumor treatment
|
|
US9750728B2
(en)
|
2012-09-29 |
2017-09-05 |
Targeted Therapeutics, Llc |
Method and pharmaceutical composition for inhibiting PI3K/AKT/mTOR signaling pathway
|
|
CN103705925B
(zh)
|
2012-09-29 |
2018-03-30 |
段磊 |
抑制PI3K/AKT/mTOR信号通路的药物组合
|
|
WO2014059295A1
(en)
|
2012-10-12 |
2014-04-17 |
The Board Of Regents Of The University Of Texas System |
Use of mtor inhibitors to treat vascular cognitive impairment
|
|
WO2014068070A1
(en)
|
2012-10-31 |
2014-05-08 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for preventing antiphospholipid syndrome (aps)
|
|
EP2919759A4
(en)
|
2012-11-14 |
2016-07-20 |
Ohio State Innovation Foundation |
MATERIALS AND METHODS FOR THE TREATMENT OF GLIOBLASTOMES
|
|
SG11201404432QA
(en)
*
|
2012-11-30 |
2014-10-30 |
Hangzhou Zylox Pharma Co Ltd |
Rafamycin analogs and methods for making same
|
|
CA2889866A1
(en)
|
2012-12-21 |
2014-06-26 |
Eisai R&D Management Co., Ltd. |
Amorphous form of quinoline derivative, and method for producing same
|
|
EP2943253B1
(en)
|
2013-01-09 |
2021-10-20 |
University Of Miami |
Compositions and methods for the regulation of t regulatory cells using tl1a-ig fusion protein and il-2
|
|
JP6330024B2
(ja)
|
2013-03-12 |
2018-05-23 |
マイセル・テクノロジーズ，インコーポレイテッド |
生体吸収性バイオメディカルインプラント
|
|
DK2968281T3
(da)
|
2013-03-13 |
2020-11-02 |
Univ Texas |
Mtor-hæmmere til forebyggelse af vækst af tarmpolyp
|
|
SG11201507093WA
(en)
|
2013-03-14 |
2015-10-29 |
Univ Maryland Baltimore Office Of Technology Transfer |
Androgen receptor down-regulating agents and uses thereof
|
|
US10098871B2
(en)
*
|
2013-03-15 |
2018-10-16 |
Leslie B. Gordon |
Combination therapies for treatment of laminopathies, cellular aging, and atherosclerosis
|
|
TW201503912A
(zh)
|
2013-03-19 |
2015-02-01 |
Novartis Ag |
包含癌莫事（ｅｖｅｒｏｌｉｍｕｓ）之醫藥組合物
|
|
WO2014182635A1
(en)
|
2013-05-08 |
2014-11-13 |
Baldwin Megan E |
Biomarkers for age-related macular degeneration (amd)
|
|
NZ714049A
(en)
|
2013-05-14 |
2020-05-29 |
Eisai R&D Man Co Ltd |
Biomarkers for predicting and assessing responsiveness of endometrial cancer subjects to lenvatinib compounds
|
|
JP2016519965A
(ja)
|
2013-05-15 |
2016-07-11 |
マイセル・テクノロジーズ，インコーポレイテッド |
生体吸収性バイオメディカルインプラント
|
|
EP3663405B8
(en)
|
2013-06-11 |
2024-10-30 |
Takara Bio USA, Inc. |
Protein enriched microvesicles and methods of making and using the same
|
|
BR112015029521A2
(pt)
*
|
2013-06-20 |
2017-07-25 |
Novartis Ag |
alquilação com um sulfonato de alquil fluoroalquila
|
|
CN103360411B
(zh)
*
|
2013-07-17 |
2015-09-30 |
成都雅途生物技术有限公司 |
依维莫司结晶提纯方法
|
|
SG11201600525XA
(en)
|
2013-08-12 |
2016-02-26 |
Tokai Pharmaceuticals Inc |
Biomarkers for treatment of neoplastic disorders using androgen-targeted therapies
|
|
US9580758B2
(en)
|
2013-11-12 |
2017-02-28 |
Luc Montagnier |
System and method for the detection and treatment of infection by a microbial agent associated with HIV infection
|
|
CA2929181A1
(en)
|
2013-11-13 |
2015-05-21 |
Novartis Ag |
Mtor inhibitors for enhancing the immune response
|
|
EP4026909A1
(en)
|
2013-12-19 |
2022-07-13 |
Novartis AG |
Human mesothelin chimeric antigen receptors and uses thereof
|
|
EP3087101B1
(en)
|
2013-12-20 |
2024-06-05 |
Novartis AG |
Regulatable chimeric antigen receptor
|
|
KR101529963B1
(ko)
*
|
2013-12-27 |
2015-06-19 |
주식회사 종근당바이오 |
에베로리무스의 제조방법 및 이의 중간체
|
|
CA2933908C
(en)
|
2013-12-31 |
2024-01-30 |
Rapamycin Holdings, Llc |
Oral rapamycin nanoparticle preparations and use
|
|
US9700544B2
(en)
|
2013-12-31 |
2017-07-11 |
Neal K Vail |
Oral rapamycin nanoparticle preparations
|
|
EP3094314B1
(en)
|
2014-01-16 |
2021-06-23 |
MUSC Foundation For Research Development |
Targeted nanocarriers for the administration of immunosuppressive agents
|
|
JP2017505345A
(ja)
|
2014-02-11 |
2017-02-16 |
ノバルティス アーゲー |
がんの処置のためのｐｉ３ｋ阻害剤を含む組合せ医薬
|
|
EP3593812A3
(en)
|
2014-03-15 |
2020-05-27 |
Novartis AG |
Treatment of cancer using chimeric antigen receptor
|
|
EP3811970A1
(en)
|
2014-03-15 |
2021-04-28 |
Novartis AG |
Regulatable chimeric antigen receptor
|
|
CN103848849B
(zh)
*
|
2014-03-24 |
2016-02-24 |
上海医药工业研究院 |
依维莫司的制备工艺
|
|
US10300070B2
(en)
|
2014-03-27 |
2019-05-28 |
The Brigham And Women's Hospital, Inc. |
Metabolically-activated drug conjugates to overcome resistance in cancer therapy
|
|
SI3888674T1
(sl)
|
2014-04-07 |
2024-08-30 |
Novartis Ag |
Zdravljenje raka z uporabo antigenskega himernega receptorja proti-CD19
|
|
WO2015171723A1
(en)
|
2014-05-06 |
2015-11-12 |
Research Development Foundation |
Methods for treating insulin resistance and for sensitizing patients to glp1 agonist therapy
|
|
CN105254646A
(zh)
*
|
2014-05-28 |
2016-01-20 |
上海博邦医药科技有限公司 |
一种制备依维莫司的方法
|
|
CA2950589A1
(en)
|
2014-06-02 |
2015-12-10 |
Children's Medical Center Corporation |
Methods and compositions for immunomodulation
|
|
JP7054622B2
(ja)
|
2014-07-21 |
2022-04-14 |
ノバルティス アーゲー |
ヒト化抗ｂｃｍａキメラ抗原受容体を使用した癌の処置
|
|
JP6831777B2
(ja)
|
2014-07-21 |
2021-02-17 |
ノバルティス アーゲー |
Ｃｄ３３キメラ抗原受容体を使用する癌の処置
|
|
EP3193915A1
(en)
|
2014-07-21 |
2017-07-26 |
Novartis AG |
Combinations of low, immune enhancing. doses of mtor inhibitors and cars
|
|
US11542488B2
(en)
|
2014-07-21 |
2023-01-03 |
Novartis Ag |
Sortase synthesized chimeric antigen receptors
|
|
WO2016019300A1
(en)
|
2014-07-31 |
2016-02-04 |
Novartis Ag |
Subset-optimized chimeric antigen receptor-containing t-cells
|
|
WO2016020664A1
(en)
*
|
2014-08-04 |
2016-02-11 |
Cipla Limited |
Process for the synthesis of everolimus and intermediates thereof
|
|
CN106715456B
(zh)
|
2014-08-12 |
2023-08-29 |
莫纳什大学 |
定向淋巴的前药
|
|
AU2015301460B2
(en)
|
2014-08-14 |
2021-04-08 |
Novartis Ag |
Treatment of cancer using GFR alpha-4 chimeric antigen receptor
|
|
WO2016028896A1
(en)
|
2014-08-19 |
2016-02-25 |
Novartis Ag |
Anti-cd123 chimeric antigen receptor (car) for use in cancer treatment
|
|
HRP20221047T1
(hr)
|
2014-08-28 |
2022-11-11 |
Eisai R&D Management Co., Ltd. |
Derivat kinolina visoke čistoće i postupak za njegovu proizvodnju
|
|
CN107073066B
(zh)
|
2014-09-11 |
2021-09-17 |
加利福尼亚大学董事会 |
mTORC1抑制剂
|
|
US10577417B2
(en)
|
2014-09-17 |
2020-03-03 |
Novartis Ag |
Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy
|
|
WO2016057705A1
(en)
|
2014-10-08 |
2016-04-14 |
Novartis Ag |
Biomarkers predictive of therapeutic responsiveness to chimeric antigen receptor therapy and uses thereof
|
|
JPWO2016068208A1
(ja)
|
2014-10-28 |
2017-08-10 |
晃史 山口 |
妊娠状態を改善するための薬剤及びその利用
|
|
WO2016066608A1
(en)
|
2014-10-28 |
2016-05-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for treatment of pulmonary cell senescence and peripheral aging
|
|
EP3473253A1
(en)
|
2014-10-29 |
2019-04-24 |
University Of Maryland |
Methods of treating age-related symptoms in mammals and compositions therefor
|
|
CN104478898A
(zh)
*
|
2014-11-18 |
2015-04-01 |
连云港恒运医药科技有限公司 |
依维莫司及其中间体的制备方法
|
|
WO2016135740A1
(en)
|
2015-02-23 |
2016-09-01 |
Natco Pharma Limited |
Process for preparing stable oral compositions of everolimus
|
|
HUE064614T2
(hu)
|
2015-02-25 |
2024-04-28 |
Eisai R&D Man Co Ltd |
Eljárás egy kinolin-származék keserû ízének elnyomására
|
|
CA2978226C
(en)
|
2015-03-04 |
2025-02-18 |
Eisai R&D Management Co., Ltd. |
COMBINATION OF A PD-1 ANTAGONIST AND A VEGFR/FGFR/RET TYROSINE KINASE INHIBITOR TO TREAT CANCER
|
|
PL3321265T3
(pl)
|
2015-03-04 |
2020-11-16 |
Gilead Sciences, Inc. |
Związki 4,6-diamino-pirydo[3,2-d]pirymidynowe i ich wykorzystanie jako modulatorów receptorów toll-podobnych
|
|
CN108473957B
(zh)
|
2015-04-17 |
2024-07-16 |
诺华股份有限公司 |
改善嵌合抗原受体表达细胞的功效和扩增的方法
|
|
EP3286211A1
(en)
|
2015-04-23 |
2018-02-28 |
Novartis AG |
Treatment of cancer using chimeric antigen receptor and protein kinase a blocker
|
|
EP3297629A1
(en)
|
2015-05-20 |
2018-03-28 |
Novartis AG |
Pharmaceutical combination of everolimus with dactolisib
|
|
CN104892632B
(zh)
*
|
2015-06-03 |
2017-12-26 |
道中道（菏泽）制药有限公司 |
一种晶体形式的依维莫司及其制备方法
|
|
BR112017027227B1
(pt)
|
2015-06-16 |
2023-12-12 |
Eisai R&D Management Co., Ltd |
Agente anti-câncer
|
|
EP3109250A1
(en)
|
2015-06-23 |
2016-12-28 |
Synbias Pharma AG |
Method for the synthesis of rapamycin derivatives
|
|
MX381976B
(es)
|
2015-08-20 |
2025-03-13 |
Eisai R&D Man Co Ltd |
Agente terapéutico contra tumores.
|
|
WO2017029391A1
(en)
|
2015-08-20 |
2017-02-23 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
New method for treating cancer
|
|
SI3307322T1
(sl)
|
2015-09-04 |
2021-08-31 |
Primatope Therapeutics Inc. |
Humanizirana protitelesa proti CD40 in njihove uporabe
|
|
EP3347340A4
(en)
|
2015-09-08 |
2019-01-23 |
Monash University |
LYMPHENLEITUNGSPRODRUGS
|
|
JP2018537447A
(ja)
|
2015-11-11 |
2018-12-20 |
ノバルティス アーゲー |
ミオスタチンアンタゴニストの使用、それを含有する組合せ物およびその使用
|
|
CN105566348A
(zh)
*
|
2015-12-31 |
2016-05-11 |
哈药集团技术中心 |
一种依维莫司的制备方法
|
|
CA3021001A1
(en)
|
2016-04-14 |
2017-10-19 |
Spinnaker Biosciences, Inc. |
Porous silicon materials comprising a metal silicate for delivery of therapeutic agents
|
|
US20190290593A1
(en)
*
|
2016-04-29 |
2019-09-26 |
Icahn School Of Medicine At Mount Sinai |
Targeting the innate immune system to induce long-term tolerance and to resolve macrophage accumulation in atherosclerosis
|
|
EP3466424A1
(en)
|
2016-05-27 |
2019-04-10 |
Nippon Kayaku Kabushiki Kaisha |
Pharmaceutical composition comprizing rapamycin or derivative thereof
|
|
EP3487878A4
(en)
|
2016-07-20 |
2020-03-25 |
University of Utah Research Foundation |
CAR-T CD229 LYMPHOCYTES AND METHODS OF USE
|
|
CA3035346A1
(en)
|
2016-09-02 |
2018-03-08 |
Gilead Sciences, Inc. |
Toll like receptor modulator compounds
|
|
EP3507288B1
(en)
|
2016-09-02 |
2020-08-26 |
Gilead Sciences, Inc. |
4,6-diamino-pyrido[3,2-d]pyrimidine derivaties as toll like receptor modulators
|
|
CN110225927B
(zh)
|
2016-10-07 |
2024-01-12 |
诺华股份有限公司 |
用于治疗癌症的嵌合抗原受体
|
|
AU2017363970A1
(en)
|
2016-11-23 |
2019-06-20 |
Novartis Ag |
Methods of enhancing immune response with everolimus, dactolisib or both
|
|
EP3548894B1
(en)
|
2016-12-02 |
2021-10-20 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and compositions for diagnosing renal cell carcinoma
|
|
PL3558955T3
(pl)
|
2016-12-22 |
2021-12-27 |
Amgen Inc. |
Pochodne benzoizotiazolu, izotiazolo[3,4-b]pirydyny, chinazoliny, ftalazyny, pirydo[2,3-d]pirydazyny i pirydo[2,3-d]pirymidyny jako inhibitory kras g12c do leczenia raka płuc, trzustki lub jelita grubego
|
|
GB201701087D0
(en)
|
2017-01-23 |
2017-03-08 |
Univ Leuven Kath |
Novel prodrugs of mizoribine
|
|
KR102539920B1
(ko)
|
2017-02-08 |
2023-06-05 |
에자이 알앤드디 매니지먼트 가부시키가이샤 |
종양-치료용 약제학적 조성물
|
|
WO2018148508A1
(en)
|
2017-02-10 |
2018-08-16 |
Mount Tam Biotechnologies, Inc. |
Rapamycin analog
|
|
EP3615055A1
(en)
|
2017-04-28 |
2020-03-04 |
Novartis AG |
Cells expressing a bcma-targeting chimeric antigen receptor, and combination therapy with a gamma secretase inhibitor
|
|
ES2871499T3
(es)
|
2017-05-15 |
2021-10-29 |
Bard Inc C R |
Dispositivo médico con recubrimiento de elución de fármaco y capa intermedia
|
|
RU2019134940A
(ru)
|
2017-05-16 |
2021-06-16 |
Эйсай Ар Энд Ди Менеджмент Ко., Лтд. |
Лечение гепатоцеллюлярной карциномы
|
|
JOP20190272A1
(ar)
|
2017-05-22 |
2019-11-21 |
Amgen Inc |
مثبطات kras g12c وطرق لاستخدامها
|
|
EP3644997A1
(en)
|
2017-06-26 |
2020-05-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for the treatment of olmsted syndrome
|
|
EP3652306A1
(en)
|
2017-07-13 |
2020-05-20 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for increasing expansion and immunosuppressive capacity of a population of cd8+cd45rclow/-tregs
|
|
AU2018324037A1
(en)
|
2017-08-29 |
2020-04-16 |
Monash University |
Lymphatic system-directing lipid prodrugs
|
|
US11883497B2
(en)
|
2017-08-29 |
2024-01-30 |
Puretech Lyt, Inc. |
Lymphatic system-directing lipid prodrugs
|
|
ES2928576T3
(es)
|
2017-09-08 |
2022-11-21 |
Amgen Inc |
Inhibidores de KRAS G12C y métodos de uso de los mismos
|
|
UY37900A
(es)
|
2017-09-26 |
2019-04-30 |
Novartis Ag |
Nuevos derivados de rapamicina
|
|
CN108047265A
(zh)
*
|
2017-11-24 |
2018-05-18 |
成都海创药业有限公司 |
一种依维莫司中间体的制备纯化方法
|
|
US11608345B1
(en)
|
2017-12-19 |
2023-03-21 |
Puretech Lyt, Inc. |
Lipid prodrugs of rapamycin and its analogs and uses thereof
|
|
US11304954B2
(en)
|
2017-12-19 |
2022-04-19 |
Puretech Lyt, Inc. |
Lipid prodrugs of mycophenolic acid and uses thereof
|
|
WO2019157516A1
(en)
|
2018-02-12 |
2019-08-15 |
resTORbio, Inc. |
Combination therapies
|
|
WO2019210153A1
(en)
|
2018-04-27 |
2019-10-31 |
Novartis Ag |
Car t cell therapies with enhanced efficacy
|
|
WO2019213282A1
(en)
|
2018-05-01 |
2019-11-07 |
Novartis Ag |
Biomarkers for evaluating car-t cells to predict clinical outcome
|
|
PE20212112A1
(es)
|
2018-05-01 |
2021-11-04 |
Revolution Medicines Inc |
Analogos de rapamicina ligados a c40, c28 y c-32 como inhibidores de mtor
|
|
KR102859103B1
(ko)
|
2018-05-01 |
2025-09-12 |
레볼루션 메디슨즈, 인크. |
mTOR 억제제로서의 C26-연결된 라파마이신 유사체
|
|
MX2020010836A
(es)
|
2018-05-04 |
2021-01-08 |
Amgen Inc |
Inhibidores de kras g12c y métodos para su uso.
|
|
CA3099118A1
(en)
|
2018-05-04 |
2019-11-07 |
Amgen Inc. |
Kras g12c inhibitors and methods of using the same
|
|
MA52564A
(fr)
|
2018-05-10 |
2021-03-17 |
Amgen Inc |
Inhibiteurs de kras g12c pour le traitement du cancer
|
|
EP3796948A4
(en)
|
2018-05-22 |
2022-03-02 |
Interface Biologics Inc. |
Compositions and methods for delivering drugs to a vessel wall
|
|
UY38247A
(es)
|
2018-05-30 |
2019-12-31 |
Novartis Ag |
Anticuerpos frente a entpd2, terapias de combinación y métodos de uso de los anticuerpos y las terapias de combinación
|
|
WO2019232419A1
(en)
|
2018-06-01 |
2019-12-05 |
Amgen Inc. |
Kras g12c inhibitors and methods of using the same
|
|
EP4268898A3
(en)
|
2018-06-11 |
2024-01-17 |
Amgen Inc. |
Kras g12c inhibitors for treating cancer
|
|
MA51848A
(fr)
|
2018-06-12 |
2021-04-21 |
Amgen Inc |
Inhibiteurs de kras g12c et leurs procédés d'utilisation
|
|
CN112203725A
(zh)
|
2018-06-13 |
2021-01-08 |
诺华股份有限公司 |
Bcma嵌合抗原受体及其用途
|
|
CN108676014A
(zh)
*
|
2018-06-15 |
2018-10-19 |
国药集团川抗制药有限公司 |
纯化依维莫司中间体的方法以及制备依维莫司的方法
|
|
JP2022510573A
(ja)
|
2018-07-23 |
2022-01-27 |
エンクリアー セラピーズ， インク． |
神経障害の治療方法
|
|
CA3107352A1
(en)
|
2018-07-23 |
2020-01-30 |
Enclear Therapies, Inc. |
Methods of treating neurological disorders
|
|
EP3849545A1
(en)
|
2018-09-10 |
2021-07-21 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Methods for the treatment of neurofibromatosis
|
|
WO2020071457A1
(en)
|
2018-10-05 |
2020-04-09 |
Eisai R&D Management Co., Ltd. |
Biomarkers for a combination therapy comprising lenvatinib and everolimus
|
|
CN113226389B
(zh)
|
2018-11-14 |
2022-11-08 |
乐通公司 |
在经改性设备表面上具有药物洗脱涂层的医疗设备
|
|
JP7516029B2
(ja)
|
2018-11-16 |
2024-07-16 |
アムジエン・インコーポレーテツド |
Ｋｒａｓ ｇ１２ｃ阻害剤化合物の重要な中間体の改良合成法
|
|
CA3117222A1
(en)
|
2018-11-19 |
2020-05-28 |
Amgen Inc. |
Kras g12c inhibitors and methods of using the same
|
|
JP7377679B2
(ja)
|
2018-11-19 |
2023-11-10 |
アムジエン・インコーポレーテツド |
がん治療のためのｋｒａｓｇ１２ｃ阻害剤及び１種以上の薬学的に活性な追加の薬剤を含む併用療法
|
|
FI3898637T3
(fi)
|
2018-12-18 |
2025-02-24 |
Novartis Ag |
Rapamysiinijohdannaisia
|
|
JP2022513967A
(ja)
|
2018-12-20 |
2022-02-09 |
アムジエン・インコーポレーテツド |
Ｋｉｆ１８ａ阻害剤として有用なヘテロアリールアミド
|
|
US12441736B2
(en)
|
2018-12-20 |
2025-10-14 |
Amgen Inc. |
KIF18A inhibitors
|
|
CA3123042A1
(en)
|
2018-12-20 |
2020-06-25 |
Amgen Inc. |
Kif18a inhibitors
|
|
IL283639B2
(en)
|
2018-12-20 |
2024-06-01 |
Amgen Inc |
Kif18a inhibitors
|
|
KR20210107069A
(ko)
|
2018-12-21 |
2021-08-31 |
다이이찌 산쿄 가부시키가이샤 |
항체-약물 컨쥬게이트와 키나아제 저해제의 조합
|
|
AU2020210921B2
(en)
*
|
2019-01-22 |
2022-02-03 |
Aeovian Pharmaceuticals, Inc. |
Mtorc modulators and uses thereof
|
|
AU2020232616A1
(en)
|
2019-03-01 |
2021-09-09 |
Revolution Medicines, Inc. |
Bicyclic heterocyclyl compounds and uses thereof
|
|
US20230148450A9
(en)
|
2019-03-01 |
2023-05-11 |
Revolution Medicines, Inc. |
Bicyclic heteroaryl compounds and uses thereof
|
|
CN113939324A
(zh)
|
2019-04-08 |
2022-01-14 |
巴德外周血管股份有限公司 |
在经改性装置表面上具有药物洗脱涂层的医疗装置
|
|
CN114007665B
(zh)
|
2019-04-11 |
2024-11-12 |
因柯利尔疗法公司 |
改善脑脊液的方法及其装置和系统
|
|
TW202210480A
(zh)
|
2019-04-17 |
2022-03-16 |
美商基利科學股份有限公司 |
類鐸受體調節劑之固體形式
|
|
TW202212339A
(zh)
|
2019-04-17 |
2022-04-01 |
美商基利科學股份有限公司 |
類鐸受體調節劑之固體形式
|
|
EP3738593A1
(en)
|
2019-05-14 |
2020-11-18 |
Amgen, Inc |
Dosing of kras inhibitor for treatment of cancers
|
|
NZ782284A
(en)
|
2019-05-21 |
2024-11-29 |
Amgen Inc |
Solid state forms
|
|
TWI879779B
(zh)
|
2019-06-28 |
2025-04-11 |
美商基利科學股份有限公司 |
類鐸受體調節劑化合物的製備方法
|
|
TW202114681A
(zh)
|
2019-07-02 |
2021-04-16 |
美商ｅＦＦＥＣＴＯＲ醫療公司 |
轉譯抑制劑及其用途
|
|
JP7699100B2
(ja)
|
2019-08-02 |
2025-06-26 |
アムジエン・インコーポレーテツド |
Ｋｉｆ１８ａ阻害剤
|
|
CN114269731A
(zh)
|
2019-08-02 |
2022-04-01 |
美国安进公司 |
Kif18a抑制剂
|
|
JP7756070B2
(ja)
|
2019-08-02 |
2025-10-17 |
アムジエン・インコーポレーテツド |
Ｋｉｆ１８ａ阻害剤としてのピリジン誘導体
|
|
WO2021026098A1
(en)
|
2019-08-02 |
2021-02-11 |
Amgen Inc. |
Kif18a inhibitors
|
|
CN114667147B
(zh)
|
2019-08-26 |
2024-09-06 |
阿尔维纳斯运营股份有限公司 |
用四氢萘衍生物作为雌激素受体降解剂的治疗乳腺癌的方法
|
|
EP4031578A1
(en)
|
2019-09-18 |
2022-07-27 |
Novartis AG |
Entpd2 antibodies, combination therapies, and methods of using the antibodies and combination therapies
|
|
WO2021055728A1
(en)
|
2019-09-18 |
2021-03-25 |
Merck Sharp & Dohme Corp. |
Small molecule inhibitors of kras g12c mutant
|
|
MX2022004656A
(es)
|
2019-10-24 |
2022-05-25 |
Amgen Inc |
Derivados de piridopirimidina utiles como inhibidores de kras g12c y kras g12d en el tratamiento del cancer.
|
|
CA3158793A1
(en)
|
2019-10-28 |
2021-05-06 |
Merck Sharp & Dohme Corp. |
Small molecule inhibitors of kras g12c mutant
|
|
JP2023515235A
(ja)
|
2019-10-31 |
2023-04-12 |
大鵬薬品工業株式会社 |
４－アミノブタ－２－エンアミド誘導体及びその塩
|
|
EP4055028A1
(en)
|
2019-11-04 |
2022-09-14 |
Revolution Medicines, Inc. |
Ras inhibitors
|
|
KR20220109406A
(ko)
|
2019-11-04 |
2022-08-04 |
레볼루션 메디슨즈, 인크. |
Ras 억제제
|
|
CA3159561A1
(en)
|
2019-11-04 |
2021-05-14 |
Revolution Medicines, Inc. |
Ras inhibitors
|
|
EP4620531A3
(en)
|
2019-11-08 |
2025-11-26 |
Revolution Medicines, Inc. |
Bicyclic heteroaryl compounds and uses thereof
|
|
JP2023501522A
(ja)
|
2019-11-14 |
2023-01-18 |
アムジエン・インコーポレーテツド |
Ｋｒａｓ ｇ１２ｃ阻害剤化合物の改良合成法
|
|
AR120457A1
(es)
|
2019-11-14 |
2022-02-16 |
Amgen Inc |
Síntesis mejorada del compuesto inhibidor de g12c de kras
|
|
WO2021108683A1
(en)
|
2019-11-27 |
2021-06-03 |
Revolution Medicines, Inc. |
Covalent ras inhibitors and uses thereof
|
|
WO2021106231A1
(en)
|
2019-11-29 |
2021-06-03 |
Taiho Pharmaceutical Co., Ltd. |
A compound having inhibitory activity against kras g12d mutation
|
|
WO2021118924A2
(en)
|
2019-12-12 |
2021-06-17 |
Ting Therapeutics Llc |
Compositions and methods for the prevention and treatment of hearing loss
|
|
TW202140011A
(zh)
|
2020-01-07 |
2021-11-01 |
美商銳新醫藥公司 |
Shp2抑制劑給藥和治療癌症的方法
|
|
WO2021159021A1
(en)
|
2020-02-05 |
2021-08-12 |
Puretech Lyt, Inc. |
Lipid prodrugs of neurosteroids
|
|
EP4139299B1
(en)
|
2020-04-24 |
2025-12-17 |
Taiho Pharmaceutical Co., Ltd. |
Kras g12d protein inhibitors
|
|
WO2021215545A1
(en)
|
2020-04-24 |
2021-10-28 |
Taiho Pharmaceutical Co., Ltd. |
Anticancer combination therapy with n-(1-acryloyl-azetidin-3-yl)-2-((1h-indazol-3-yl)amino)methyl)-1h-imidazole-5-carboxamide inhibitor of kras-g12c
|
|
AU2021308045B2
(en)
|
2020-07-15 |
2024-06-20 |
Taiho Pharmaceutical Co., Ltd. |
Pyrimidine compound-containing combination to be used in tumor treatment
|
|
US20250195521A1
(en)
|
2020-09-03 |
2025-06-19 |
Revolution Medicines, Inc. |
Use of sos1 inhibitors to treat malignancies with shp2 mutations
|
|
IL301298A
(en)
|
2020-09-15 |
2023-05-01 |
Revolution Medicines Inc |
Indole derivatives as RAS inhibitors in cancer therapy
|
|
AU2021355470A1
(en)
|
2020-09-29 |
2023-06-01 |
Enclear Therapies, Inc. |
Subarachnoid fluid management method and system
|
|
JP2024501280A
(ja)
|
2020-12-22 |
2024-01-11 |
キル・レガー・セラピューティクス・インコーポレーテッド |
Ｓｏｓ１阻害剤およびその使用
|
|
AU2022239614A1
(en)
|
2021-03-19 |
2023-10-12 |
Icahn School Of Medicine At Mount Sinai |
Compounds for regulating trained immunity, and their methods of use
|
|
TW202309052A
(zh)
|
2021-05-05 |
2023-03-01 |
美商銳新醫藥公司 |
Ｒａｓ抑制劑
|
|
WO2022235870A1
(en)
|
2021-05-05 |
2022-11-10 |
Revolution Medicines, Inc. |
Ras inhibitors for the treatment of cancer
|
|
EP4334324A1
(en)
|
2021-05-05 |
2024-03-13 |
Revolution Medicines, Inc. |
Covalent ras inhibitors and uses thereof
|
|
EP4347041A1
(en)
|
2021-05-28 |
2024-04-10 |
Taiho Pharmaceutical Co., Ltd. |
Small molecule inhibitors of kras mutated proteins
|
|
EP4370160A1
(en)
|
2021-07-15 |
2024-05-22 |
President And Fellows Of Harvard College |
Compositions and methods relating to cells with adhered particles
|
|
AR127308A1
(es)
|
2021-10-08 |
2024-01-10 |
Revolution Medicines Inc |
Inhibidores ras
|
|
TW202340214A
(zh)
|
2021-12-17 |
2023-10-16 |
美商健臻公司 |
做為shp2抑制劑之吡唑并吡𠯤化合物
|
|
EP4227307A1
(en)
|
2022-02-11 |
2023-08-16 |
Genzyme Corporation |
Pyrazolopyrazine compounds as shp2 inhibitors
|
|
JP2025509217A
(ja)
|
2022-03-07 |
2025-04-11 |
アムジエン・インコーポレーテツド |
４－メチル－２－プロパン－２－イル－ピリジン－３－カルボニトリルを調製するための方法
|
|
WO2023172940A1
(en)
|
2022-03-08 |
2023-09-14 |
Revolution Medicines, Inc. |
Methods for treating immune refractory lung cancer
|
|
CA3256390A1
(en)
|
2022-05-25 |
2023-11-30 |
Revolution Medicines, Inc. |
CANCER TREATMENT METHODS USING AN MTOR INHIBITOR
|
|
KR20250022133A
(ko)
|
2022-06-10 |
2025-02-14 |
레볼루션 메디슨즈, 인크. |
거대고리 ras 억제제
|
|
EP4551219A1
(en)
|
2022-07-06 |
2025-05-14 |
Institut National de la Santé et de la Recherche Médicale |
Methods for the treatment of proliferative glomerulonephritis
|
|
EP4565217A1
(en)
|
2022-08-04 |
2025-06-11 |
Institut National de la Santé et de la Recherche Médicale |
Methods for the treatment of lymphoproliferative disorders
|
|
AU2023358792A1
(en)
|
2022-10-14 |
2025-04-17 |
Black Diamond Therapeutics, Inc. |
Methods of treating cancers using isoquinoline or 6-aza-quinoline derivatives
|
|
CN120187416A
(zh)
|
2022-11-11 |
2025-06-20 |
阿斯利康(瑞典)有限公司 |
用于治疗癌症的组合疗法
|
|
WO2024167904A1
(en)
|
2023-02-07 |
2024-08-15 |
Arvinas Operations, Inc. |
Dosage regimens of estrogen receptor degraders in combination with an mtor inhibitor
|
|
KR20250164828A
(ko)
|
2023-03-30 |
2025-11-25 |
레볼루션 메디슨즈, 인크. |
Ras gtp 가수분해 유도를 위한 조성물 및 이의 용도
|
|
AU2024243852A1
(en)
|
2023-04-07 |
2025-11-06 |
Revolution Medicines, Inc. |
Macrocyclic ras inhibitors
|
|
WO2024211663A1
(en)
|
2023-04-07 |
2024-10-10 |
Revolution Medicines, Inc. |
Condensed macrocyclic compounds as ras inhibitors
|
|
KR20250172857A
(ko)
|
2023-04-14 |
2025-12-09 |
레볼루션 메디슨즈, 인크. |
Ras 억제제의 결정형
|
|
KR20250169290A
(ko)
|
2023-04-14 |
2025-12-02 |
레볼루션 메디슨즈, 인크. |
Ras 억제제의 결정형, 이를 함유하는 조성물 및 이의 사용 방법
|
|
AU2024265078A1
(en)
|
2023-05-04 |
2025-12-11 |
Revolution Medicines, Inc. |
Combination therapy for a ras related disease or disorder
|
|
CN116813641A
(zh)
*
|
2023-06-09 |
2023-09-29 |
杭州华东医药集团康润制药有限公司 |
一种依维莫司的制备方法
|
|
WO2025034702A1
(en)
|
2023-08-07 |
2025-02-13 |
Revolution Medicines, Inc. |
Rmc-6291 for use in the treatment of ras protein-related disease or disorder
|
|
TW202515582A
(zh)
|
2023-08-24 |
2025-04-16 |
日商大塚製藥股份有限公司 |
西區嘧啶(cedazuridine)之固定劑量組合
|
|
WO2025080946A2
(en)
|
2023-10-12 |
2025-04-17 |
Revolution Medicines, Inc. |
Ras inhibitors
|
|
WO2025085748A1
(en)
|
2023-10-20 |
2025-04-24 |
Merck Sharp & Dohme Llc |
Small molecule inhibitors of kras proteins
|
|
WO2025137507A1
(en)
|
2023-12-22 |
2025-06-26 |
Regor Pharmaceuticals, Inc. |
Sos1 inhibitors and uses thereof
|
|
WO2025171296A1
(en)
|
2024-02-09 |
2025-08-14 |
Revolution Medicines, Inc. |
Ras inhibitors
|
|
WO2025240847A1
(en)
|
2024-05-17 |
2025-11-20 |
Revolution Medicines, Inc. |
Ras inhibitors
|
|
WO2025255438A1
(en)
|
2024-06-07 |
2025-12-11 |
Revolution Medicines, Inc. |
Methods of treating a ras protein-related disease or disorder
|