KR102179751B1 - 이중 glp1/글루카곤 작용제로서의 엑센딘-4 유도체 - Google Patents

이중 glp1/글루카곤 작용제로서의 엑센딘-4 유도체 Download PDF

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KR102179751B1
KR102179751B1 KR1020157010088A KR20157010088A KR102179751B1 KR 102179751 B1 KR102179751 B1 KR 102179751B1 KR 1020157010088 A KR1020157010088 A KR 1020157010088A KR 20157010088 A KR20157010088 A KR 20157010088A KR 102179751 B1 KR102179751 B1 KR 102179751B1
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carboxy
butyryl
ethoxy
amino acid
acid residue
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토르스텐 하아크
미하엘 바그너
베른트 헨켈
지그프리트 스텐겔린
안드레아스 에페르스
마르틴 보싸르트
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    • C—CHEMISTRY; METALLURGY
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    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • A—HUMAN NECESSITIES
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    • A61K38/22—Hormones
    • A61K38/26—Glucagons
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    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
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    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C07—ORGANIC CHEMISTRY
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    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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  • Proteomics, Peptides & Aminoacids (AREA)
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KR1020157010088A 2012-10-09 2013-10-08 이중 glp1/글루카곤 작용제로서의 엑센딘-4 유도체 Active KR102179751B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP12306232.5 2012-10-09
EP12306232 2012-10-09
EP13305222.5 2013-02-27
EP13305222 2013-02-27
PCT/EP2013/070882 WO2014056872A1 (en) 2012-10-09 2013-10-08 Exendin-4 derivatives as dual glp1/glucagon agonists

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KR20150064093A KR20150064093A (ko) 2015-06-10
KR102179751B1 true KR102179751B1 (ko) 2020-11-17

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EP (1) EP2906595B1 (enExample)
JP (1) JP6373270B2 (enExample)
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CN (1) CN104837864B (enExample)
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JP2025524736A (ja) * 2022-06-07 2025-07-31 ヘリコア・バイオファーマ・インコーポレイテッド 体位性頻脈症候群を処置するための組成物及び方法
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