MX2012006744A - Tiazolidinadionas reguladores de receptores activados por proliferador de peroxisoma (ppar) y combinaciones para el tratamiento de diabetes mellitus y otras enfermedades metabolicas. - Google Patents
Tiazolidinadionas reguladores de receptores activados por proliferador de peroxisoma (ppar) y combinaciones para el tratamiento de diabetes mellitus y otras enfermedades metabolicas.Info
- Publication number
- MX2012006744A MX2012006744A MX2012006744A MX2012006744A MX2012006744A MX 2012006744 A MX2012006744 A MX 2012006744A MX 2012006744 A MX2012006744 A MX 2012006744A MX 2012006744 A MX2012006744 A MX 2012006744A MX 2012006744 A MX2012006744 A MX 2012006744A
- Authority
- MX
- Mexico
- Prior art keywords
- treatment
- ppar
- combinations
- diabetes mellitus
- metabolic diseases
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Abstract
La presente invención se refiere a análogos de tiazolidinadionas y composiciones farmacéuticas que son útiles para tratar y/o prevenir diabetes mellitus, opcionalmente en combinción con un segundo tratamientol. Adicionalmente, la presente invención también proporciona métodos para inducir la remisión de los síntomas de diabetes mellitus en un paciente que comprende en administrar un análogo de tiazolinidinadionas y un agonista de GLP-1.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US28673809P | 2009-12-15 | 2009-12-15 | |
US28676509P | 2009-12-15 | 2009-12-15 | |
US29674810P | 2010-01-20 | 2010-01-20 | |
PCT/US2010/060453 WO2011084456A1 (en) | 2009-12-15 | 2010-12-15 | Ppar-sparing thiazolidinediones and combinations for the treatment of diabetes mellitus and other metabolic diseases |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2012006744A true MX2012006744A (es) | 2012-07-30 |
Family
ID=43707800
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2012006744A MX2012006744A (es) | 2009-12-15 | 2010-12-15 | Tiazolidinadionas reguladores de receptores activados por proliferador de peroxisoma (ppar) y combinaciones para el tratamiento de diabetes mellitus y otras enfermedades metabolicas. |
Country Status (10)
Country | Link |
---|---|
US (1) | US20120322728A1 (es) |
EP (1) | EP2512471A1 (es) |
JP (1) | JP2013514369A (es) |
KR (1) | KR20120092712A (es) |
CN (1) | CN102753170A (es) |
AU (1) | AU2010340058A1 (es) |
CA (1) | CA2783264A1 (es) |
MX (1) | MX2012006744A (es) |
RU (1) | RU2012130011A (es) |
WO (1) | WO2011084456A1 (es) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2783468C (en) | 2009-12-15 | 2018-10-09 | Metabolic Solutions Development Company, Llc | Ppar-sparing thiazolidinedione salts for the treatment of metabolic diseases |
US9907767B2 (en) | 2010-08-03 | 2018-03-06 | Velicept Therapeutics, Inc. | Pharmaceutical compositions and the treatment of overactive bladder |
UA116217C2 (uk) | 2012-10-09 | 2018-02-26 | Санофі | Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону |
AU2013366691A1 (en) | 2012-12-21 | 2015-07-09 | Sanofi | Exendin-4 derivatives |
TW201609797A (zh) | 2013-12-13 | 2016-03-16 | 賽諾菲公司 | 雙重glp-1/升糖素受體促效劑 |
EP3080150B1 (en) | 2013-12-13 | 2018-08-01 | Sanofi | Exendin-4 peptide analogues as dual glp-1/gip receptor agonists |
TW201609796A (zh) | 2013-12-13 | 2016-03-16 | 賽諾菲公司 | 非醯化之艾塞那肽-4(exendin-4)胜肽類似物 |
TW201609799A (zh) | 2013-12-13 | 2016-03-16 | 賽諾菲公司 | 雙重glp-1/gip受體促效劑 |
TW201625669A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 衍生自艾塞那肽-4(Exendin-4)之肽類雙重GLP-1/升糖素受體促效劑 |
TW201625670A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 衍生自exendin-4之雙重glp-1/升糖素受體促效劑 |
TW201625668A (zh) | 2014-04-07 | 2016-07-16 | 賽諾菲公司 | 作為胜肽性雙重glp-1/昇糖素受體激動劑之艾塞那肽-4衍生物 |
US9932381B2 (en) | 2014-06-18 | 2018-04-03 | Sanofi | Exendin-4 derivatives as selective glucagon receptor agonists |
AR105319A1 (es) | 2015-06-05 | 2017-09-27 | Sanofi Sa | Profármacos que comprenden un conjugado agonista dual de glp-1 / glucagón conector ácido hialurónico |
TW201706291A (zh) | 2015-07-10 | 2017-02-16 | 賽諾菲公司 | 作為選擇性肽雙重glp-1/升糖素受體促效劑之新毒蜥外泌肽(exendin-4)衍生物 |
WO2017070689A2 (en) | 2015-10-23 | 2017-04-27 | Velicept Therapeutics, Inc. | Solabegron zwitterion and uses thereof |
US20210038566A1 (en) | 2018-02-08 | 2021-02-11 | Enyo Pharma | Use of modulators of neet proteins for the treatment of infection |
US11931345B2 (en) * | 2018-05-04 | 2024-03-19 | Cirius Therapeutics, Inc. | Thiazolidinedione analogs for the treatment of NAFLD and metabolic diseases |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5304121A (en) | 1990-12-28 | 1994-04-19 | Boston Scientific Corporation | Drug delivery system making use of a hydrogel polymer coating |
US5441971A (en) * | 1991-04-11 | 1995-08-15 | The Upjohn Company | Thiazolidinedione derivatives, production and use thereof |
US5716981A (en) | 1993-07-19 | 1998-02-10 | Angiogenesis Technologies, Inc. | Anti-angiogenic compositions and methods of use |
US6099562A (en) | 1996-06-13 | 2000-08-08 | Schneider (Usa) Inc. | Drug coating with topcoat |
US7230016B2 (en) * | 2003-05-13 | 2007-06-12 | Synthon Ip Inc. | Pioglitazone salts, such as pioglitazone sulfate, and pharmaceutical compositions and processes using the same |
CN101448500A (zh) * | 2006-03-16 | 2009-06-03 | 新陈代谢解决方案开发公司 | 噻唑烷二酮类似物和糖皮质激素激动剂的组合疗法 |
ES2397944T3 (es) * | 2006-03-16 | 2013-03-12 | Metabolic Solutions Development Company Llc | Análogos de tiazolidindiona |
RU2486179C2 (ru) * | 2007-09-14 | 2013-06-27 | МЕТАБОЛИК СОЛЮШНЗ ДЕВЕЛОПМЕНТ КОМПАНИ, ЭлЭлСи | Аналоги тиазолидиндиона для лечения диабета и дислипидемии |
WO2010105048A1 (en) * | 2009-03-12 | 2010-09-16 | Metabolic Solutions Development Company | Thiazolidinedione analogues |
-
2010
- 2010-12-15 JP JP2012544745A patent/JP2013514369A/ja not_active Withdrawn
- 2010-12-15 KR KR1020127018393A patent/KR20120092712A/ko not_active Application Discontinuation
- 2010-12-15 CN CN2010800639462A patent/CN102753170A/zh active Pending
- 2010-12-15 US US13/515,549 patent/US20120322728A1/en not_active Abandoned
- 2010-12-15 RU RU2012130011/15A patent/RU2012130011A/ru not_active Application Discontinuation
- 2010-12-15 EP EP10801494A patent/EP2512471A1/en not_active Withdrawn
- 2010-12-15 AU AU2010340058A patent/AU2010340058A1/en not_active Abandoned
- 2010-12-15 WO PCT/US2010/060453 patent/WO2011084456A1/en active Application Filing
- 2010-12-15 CA CA2783264A patent/CA2783264A1/en not_active Abandoned
- 2010-12-15 MX MX2012006744A patent/MX2012006744A/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO2011084456A9 (en) | 2012-06-21 |
CA2783264A1 (en) | 2011-07-14 |
CN102753170A (zh) | 2012-10-24 |
RU2012130011A (ru) | 2014-01-27 |
EP2512471A1 (en) | 2012-10-24 |
WO2011084456A1 (en) | 2011-07-14 |
JP2013514369A (ja) | 2013-04-25 |
AU2010340058A1 (en) | 2012-06-21 |
US20120322728A1 (en) | 2012-12-20 |
KR20120092712A (ko) | 2012-08-21 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |