KR101847485B1 - 초속효성 인슐린의 용도 - Google Patents
초속효성 인슐린의 용도 Download PDFInfo
- Publication number
- KR101847485B1 KR101847485B1 KR1020157034895A KR20157034895A KR101847485B1 KR 101847485 B1 KR101847485 B1 KR 101847485B1 KR 1020157034895 A KR1020157034895 A KR 1020157034895A KR 20157034895 A KR20157034895 A KR 20157034895A KR 101847485 B1 KR101847485 B1 KR 101847485B1
- Authority
- KR
- South Korea
- Prior art keywords
- insulin
- meal
- glucose
- dose
- pharmaceutical agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/545—Heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0021—Intradermal administration, e.g. through microneedle arrays or needleless injectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Dermatology (AREA)
- Pulmonology (AREA)
- Otolaryngology (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8794308P | 2008-08-11 | 2008-08-11 | |
| US61/087,943 | 2008-08-11 | ||
| US9749508P | 2008-09-16 | 2008-09-16 | |
| US9751608P | 2008-09-16 | 2008-09-16 | |
| US61/097,495 | 2008-09-16 | ||
| US61/097,516 | 2008-09-16 | ||
| US13886308P | 2008-12-18 | 2008-12-18 | |
| US61/138,863 | 2008-12-18 | ||
| PCT/US2009/053443 WO2010021879A2 (en) | 2008-08-11 | 2009-08-11 | Use of ultrarapid acting insulin |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020117004601A Division KR20110052664A (ko) | 2008-08-11 | 2009-08-11 | 초속효성 인슐린의 용도 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020187009530A Division KR20180037330A (ko) | 2008-08-11 | 2009-08-11 | 초속효성 인슐린의 용도 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20150143894A KR20150143894A (ko) | 2015-12-23 |
| KR101847485B1 true KR101847485B1 (ko) | 2018-04-11 |
Family
ID=41653492
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020157034895A Active KR101847485B1 (ko) | 2008-08-11 | 2009-08-11 | 초속효성 인슐린의 용도 |
| KR1020187009530A Ceased KR20180037330A (ko) | 2008-08-11 | 2009-08-11 | 초속효성 인슐린의 용도 |
| KR1020117004601A Ceased KR20110052664A (ko) | 2008-08-11 | 2009-08-11 | 초속효성 인슐린의 용도 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020187009530A Ceased KR20180037330A (ko) | 2008-08-11 | 2009-08-11 | 초속효성 인슐린의 용도 |
| KR1020117004601A Ceased KR20110052664A (ko) | 2008-08-11 | 2009-08-11 | 초속효성 인슐린의 용도 |
Country Status (14)
| Country | Link |
|---|---|
| US (13) | US8258095B2 (https=) |
| EP (2) | EP3207942B1 (https=) |
| JP (5) | JP5869339B2 (https=) |
| KR (3) | KR101847485B1 (https=) |
| AU (3) | AU2009283013B2 (https=) |
| BR (1) | BRPI0917535A8 (https=) |
| CA (3) | CA2733593C (https=) |
| ES (1) | ES2930673T3 (https=) |
| MX (3) | MX357273B (https=) |
| MY (2) | MY165651A (https=) |
| RU (2) | RU2519706C2 (https=) |
| SG (2) | SG10202010801RA (https=) |
| TW (3) | TWI532497B (https=) |
| WO (1) | WO2010021879A2 (https=) |
Families Citing this family (69)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2569916T3 (es) * | 1999-06-29 | 2016-05-13 | Mannkind Corporation | Formulaciones farmacéuticas que comprenden insulina complejada con una dicetopiperazina |
| US9006175B2 (en) * | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
| US20080172026A1 (en) | 2006-10-17 | 2008-07-17 | Blomquist Michael L | Insulin pump having a suspension bolus |
| US6923175B2 (en) | 2002-03-20 | 2005-08-02 | Mannkind Corporation | Inhalation apparatus |
| US8921311B2 (en) * | 2003-08-01 | 2014-12-30 | Mannkind Corporation | Method for treating hyperglycemia |
| US20070027063A1 (en) * | 2004-01-12 | 2007-02-01 | Mannkind Corporation | Method of preserving the function of insulin-producing cells |
| ATE486064T1 (de) | 2004-08-20 | 2010-11-15 | Mannkind Corp | Katalyse der diketopiperazinsynthese |
| KR20130066695A (ko) | 2004-08-23 | 2013-06-20 | 맨카인드 코포레이션 | 약물 전달용 디케토피페라진염, 디케토모르포린염 또는 디케토디옥산염 |
| MX373000B (es) | 2005-09-14 | 2020-05-21 | Mannkind Corp | Metodo para formulacion de farmaco basado en el aumento de la afinidad de agentes activos hacia las superficies de microparticulas cristalinas. |
| EP1986679B1 (en) | 2006-02-22 | 2017-10-25 | MannKind Corporation | A method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent |
| US20080228056A1 (en) | 2007-03-13 | 2008-09-18 | Michael Blomquist | Basal rate testing using frequent blood glucose input |
| US7751907B2 (en) | 2007-05-24 | 2010-07-06 | Smiths Medical Asd, Inc. | Expert system for insulin pump therapy |
| US8221345B2 (en) | 2007-05-30 | 2012-07-17 | Smiths Medical Asd, Inc. | Insulin pump based expert system |
| US8785396B2 (en) | 2007-10-24 | 2014-07-22 | Mannkind Corporation | Method and composition for treating migraines |
| US20090177147A1 (en) | 2008-01-07 | 2009-07-09 | Michael Blomquist | Insulin pump with insulin therapy coaching |
| US20090177142A1 (en) | 2008-01-09 | 2009-07-09 | Smiths Medical Md, Inc | Insulin pump with add-on modules |
| TWI394580B (zh) | 2008-04-28 | 2013-05-01 | Halozyme Inc | 超快起作用胰島素組成物 |
| US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
| CN101827626B (zh) | 2008-06-13 | 2015-03-18 | 曼金德公司 | 干粉吸入器和用于药物输送的系统 |
| ES2421385T3 (es) | 2008-06-20 | 2013-09-02 | Mannkind Corp | Aparato interactivo y procedimiento para establecer el perfil, en tiempo real, de esfuerzos de inhalación |
| TWI532497B (zh) | 2008-08-11 | 2016-05-11 | 曼凱公司 | 超快起作用胰島素之用途 |
| US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
| AU2010217760B2 (en) | 2009-02-27 | 2015-04-09 | Tandem Diabetes Care, Inc. | Methods and devices for determination of flow reservoir volume |
| US9250106B2 (en) | 2009-02-27 | 2016-02-02 | Tandem Diabetes Care, Inc. | Methods and devices for determination of flow reservoir volume |
| DK2405963T3 (da) | 2009-03-11 | 2013-12-16 | Mannkind Corp | Apparat, system og fremgangsmåde til at måle modstand i en inhalator |
| KR102584844B1 (ko) | 2009-06-12 | 2023-10-04 | 맨카인드 코포레이션 | 한정된 비표면적을 갖는 디케토피페라진 마이크로입자 |
| EP3284494A1 (en) | 2009-07-30 | 2018-02-21 | Tandem Diabetes Care, Inc. | Portable infusion pump system |
| CA2778698A1 (en) | 2009-11-03 | 2011-05-12 | Mannkind Corporation | An apparatus and method for simulating inhalation efforts |
| US8882701B2 (en) | 2009-12-04 | 2014-11-11 | Smiths Medical Asd, Inc. | Advanced step therapy delivery for an ambulatory infusion pump and system |
| CN102985125A (zh) | 2010-06-21 | 2013-03-20 | 曼金德公司 | 干粉药物输送系统和方法 |
| SG194034A1 (en) | 2011-04-01 | 2013-11-29 | Mannkind Corp | Blister package for pharmaceutical cartridges |
| JP5771060B2 (ja) * | 2011-05-02 | 2015-08-26 | シスメックス株式会社 | 検体分析装置及びデータ処理装置 |
| WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
| US9993529B2 (en) | 2011-06-17 | 2018-06-12 | Halozyme, Inc. | Stable formulations of a hyaluronan-degrading enzyme |
| MX2014004983A (es) | 2011-10-24 | 2014-09-22 | Mannkid Corp | Metodos y composiciones para tratar dolor. |
| TW201333870A (zh) | 2011-12-21 | 2013-08-16 | 艾登工具股份有限公司 | 決定病人胰島素療法的系統及方法 |
| US9180242B2 (en) | 2012-05-17 | 2015-11-10 | Tandem Diabetes Care, Inc. | Methods and devices for multiple fluid transfer |
| US9238100B2 (en) | 2012-06-07 | 2016-01-19 | Tandem Diabetes Care, Inc. | Device and method for training users of ambulatory medical devices |
| KR102264177B1 (ko) | 2012-07-12 | 2021-06-11 | 맨카인드 코포레이션 | 건조 분말 약물 전달 시스템 및 방법 |
| WO2014066856A1 (en) | 2012-10-26 | 2014-05-01 | Mannkind Corporation | Inhalable influenza vaccine compositions and methods |
| US10357606B2 (en) | 2013-03-13 | 2019-07-23 | Tandem Diabetes Care, Inc. | System and method for integration of insulin pumps and continuous glucose monitoring |
| US10201656B2 (en) | 2013-03-13 | 2019-02-12 | Tandem Diabetes Care, Inc. | Simplified insulin pump for type II diabetics |
| US9173998B2 (en) | 2013-03-14 | 2015-11-03 | Tandem Diabetes Care, Inc. | System and method for detecting occlusions in an infusion pump |
| EP3587404B1 (en) | 2013-03-15 | 2022-07-13 | MannKind Corporation | Microcrystalline diketopiperazine compositions, methods for preparation and use thereof |
| US9492608B2 (en) | 2013-03-15 | 2016-11-15 | Tandem Diabetes Care, Inc. | Method and device utilizing insulin delivery protocols |
| US10016561B2 (en) | 2013-03-15 | 2018-07-10 | Tandem Diabetes Care, Inc. | Clinical variable determination |
| US9867953B2 (en) | 2013-06-21 | 2018-01-16 | Tandem Diabetes Care, Inc. | System and method for infusion set dislodgement detection |
| MX375448B (es) | 2013-07-18 | 2025-03-06 | Mannkind Corp | Composiciones farmacéuticas en polvo seco estables al calor y métodos. |
| EP3030294B1 (en) | 2013-08-05 | 2020-10-07 | MannKind Corporation | Insufflation apparatus |
| US9486580B2 (en) | 2014-01-31 | 2016-11-08 | Aseko, Inc. | Insulin management |
| US9898585B2 (en) | 2014-01-31 | 2018-02-20 | Aseko, Inc. | Method and system for insulin management |
| US10307464B2 (en) | 2014-03-28 | 2019-06-04 | Mannkind Corporation | Use of ultrarapid acting insulin |
| WO2016019133A1 (en) | 2014-07-30 | 2016-02-04 | Tandem Diabetes Care, Inc. | Temporary suspension for closed-loop medicament therapy |
| US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
| EP3933845A3 (en) | 2014-10-27 | 2022-06-22 | Aseko, Inc. | Subcutaneous outpatient management |
| US11081226B2 (en) | 2014-10-27 | 2021-08-03 | Aseko, Inc. | Method and controller for administering recommended insulin dosages to a patient |
| EP3337402B1 (en) | 2015-08-20 | 2026-01-07 | Glytec, LLC | Diabetes management therapy advisor |
| US10569016B2 (en) | 2015-12-29 | 2020-02-25 | Tandem Diabetes Care, Inc. | System and method for switching between closed loop and open loop control of an ambulatory infusion pump |
| WO2017132601A1 (en) * | 2016-01-29 | 2017-08-03 | Mannkind Corporation | Dry powder inhaler |
| MX2018011788A (es) * | 2016-03-31 | 2019-05-20 | Janssen Pharmaceuticals Inc | Derivados de indolina sustituidos como inhibidores de la replicacion virica de dengue. |
| CN111954966B (zh) | 2018-04-10 | 2025-09-30 | 坦德姆糖尿病护理股份有限公司 | 用于对医疗设备进行感应充电的系统和方法 |
| US11116901B2 (en) | 2018-05-29 | 2021-09-14 | Tandem Diabetes Care, Inc. | Automatic detection of un-bolused meals |
| WO2020210697A1 (en) * | 2019-04-12 | 2020-10-15 | Sdg, Inc. | Lipid-based nanoparticles and use of same in optimized insulin dosing regimens |
| US11654236B2 (en) | 2019-11-22 | 2023-05-23 | Tandem Diabetes Care, Inc. | Systems and methods for automated insulin delivery for diabetes therapy |
| US11341463B2 (en) | 2019-11-25 | 2022-05-24 | International Business Machines Corporation | Blockchain ledger entry upon maintenance of asset and anomaly detection correction |
| US11449811B2 (en) | 2019-11-25 | 2022-09-20 | International Business Machines Corporation | Digital twin article recommendation consultation |
| US11291077B2 (en) | 2019-11-25 | 2022-03-29 | International Business Machines Corporation | Internet of things sensor major and minor event blockchain decisioning |
| WO2025076261A1 (en) * | 2023-10-03 | 2025-04-10 | Veru, Inc. | Uses of selective androgen receptor modulator (sarm) compounds in chronic weight management |
| WO2025166261A1 (en) * | 2024-02-01 | 2025-08-07 | University Of Virginia Patent Foundation | Method and system for calculating insulin dosing parameters in computer aided dosing |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050187749A1 (en) | 2003-10-24 | 2005-08-25 | Judy Singley | Method, system, and computer program for performing carbohydrate/insulin calculation based upon food weight |
| US20070027063A1 (en) | 2004-01-12 | 2007-02-01 | Mannkind Corporation | Method of preserving the function of insulin-producing cells |
Family Cites Families (1066)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB475440A (en) | 1935-09-23 | 1937-11-19 | Mine Safety Appliances Co | Improvements in or relating to apparatus for determining the flow resistance of breathing apparatus elements |
| US2549303A (en) | 1949-04-20 | 1951-04-17 | Bristol Lab Inc | Inhaler for crystalline pencilllin or the like |
| BE509861A (https=) | 1952-03-13 | |||
| US2754276A (en) | 1953-02-12 | 1956-07-10 | Du Pont | Cellular compositions utilizing dinitrosopentamethylene-tetramine as the blowing agent |
| US3337740A (en) | 1962-02-13 | 1967-08-22 | Deering Milliken Res Corp | Process for separating acrylic acid from impurities |
| US4187129A (en) | 1962-05-14 | 1980-02-05 | Aerojet-General Corporation | Gelled mechanically stable high energy fuel composition containing metal platelets |
| FR1451293A (fr) | 1964-05-18 | 1966-01-07 | Entoleter | Matière composite et son procédé de préparation |
| US3407203A (en) | 1965-03-22 | 1968-10-22 | Union Carbide Corp | Novel process for the preparation of diketopiperazines |
| US3669113A (en) | 1966-03-07 | 1972-06-13 | Fisons Ltd | Inhalation device |
| US3518340A (en) | 1968-04-15 | 1970-06-30 | Dow Corning | Method of forming silicone rubber drug carriers |
| US3622053A (en) | 1969-12-10 | 1971-11-23 | Schering Corp | Aerosol inhaler with flip-up nozzle |
| US3673698A (en) | 1970-11-25 | 1972-07-04 | Albert S Guerard | Process for freeze drying with carbon dioxide |
| BE794951A (fr) | 1972-02-03 | 1973-05-29 | Parke Davis & Co | Conditionnement soluble dans l'eau |
| US3873651A (en) | 1972-05-12 | 1975-03-25 | Atomic Energy Commission | Freeze drying method for preparing radiation source material |
| US3823843A (en) | 1972-10-26 | 1974-07-16 | Lilly Co Eli | Locking capsule |
| US3856142A (en) | 1973-01-24 | 1974-12-24 | Mine Safety Appliances Co | Inhalant package |
| FR2224175B1 (https=) | 1973-04-04 | 1978-04-14 | Isf Spa | |
| US3980074A (en) | 1973-07-18 | 1976-09-14 | Beecham Group Limited | Device for the administration of powders |
| GB1479283A (en) | 1973-07-23 | 1977-07-13 | Bespak Industries Ltd | Inhaler for powdered medicament |
| GB1459488A (en) | 1974-03-19 | 1976-12-22 | Wyeth John & Brother Ltd | Piperazinedione derivatives |
| IT1017153B (it) | 1974-07-15 | 1977-07-20 | Isf Spa | Apparecchio per inalazioni |
| US4018619A (en) | 1974-09-23 | 1977-04-19 | Iu Technology Corporation | Highly activated mixtures for constructing load bearing surfaces and method of making the same |
| US4005711A (en) | 1975-01-13 | 1977-02-01 | Syntex Puerto Rico, Inc. | Inhalation device |
| DE2502251A1 (de) | 1975-01-17 | 1976-07-22 | Schering Ag | Vorrichtung zur inhalation pulverfoermiger feststoffe |
| US4040536A (en) | 1975-05-05 | 1977-08-09 | R. P. Scherer Corporation | Locking hard gelatin capsule |
| LU75103A1 (https=) | 1975-06-09 | 1977-01-24 | ||
| US4153689A (en) | 1975-06-13 | 1979-05-08 | Takeda Chemical Industries, Ltd. | Stable insulin preparation for nasal administration |
| US3998226A (en) | 1975-09-22 | 1976-12-21 | Edward G. Gomez | Inhalation device for encapsulated concentrates |
| GB1509979A (en) | 1975-11-28 | 1978-05-10 | Fisons Ltd | Pharmaceutical compositions containing aspirin or indomethacin |
| US4102953A (en) | 1976-05-25 | 1978-07-25 | The United States Of America As Represented By The Secretary Of The Navy | Method for making extruded, solventless, composite-modified double base propellant |
| USD252707S (en) | 1977-01-03 | 1979-08-21 | Joel Besnard | Inhaler |
| GB1598081A (en) | 1977-02-10 | 1981-09-16 | Allen & Hanburys Ltd | Inhaler device for dispensing medicaments |
| US4171000A (en) | 1977-03-23 | 1979-10-16 | Uhle Klaus P | Smoking device |
| IE46865B1 (en) | 1977-04-29 | 1983-10-19 | Allen & Hanburys Ltd | Device for dispensing medicaments |
| US4148308A (en) | 1977-05-31 | 1979-04-10 | Sayer William J | Mouthpiece with a tongue retractor |
| US4110240A (en) | 1977-07-29 | 1978-08-29 | Wyrough And Loser, Inc. | Coprecipitation process |
| US4091077A (en) | 1977-08-12 | 1978-05-23 | The United States Of America As Represented By The United States Department Of Energy | Process for recovering filler from polymer |
| US4211769A (en) | 1977-08-24 | 1980-07-08 | Takeda Chemical Industries, Ltd. | Preparations for vaginal administration |
| US4268460A (en) | 1977-12-12 | 1981-05-19 | Warner-Lambert Company | Nebulizer |
| CA1113044A (en) | 1977-12-16 | 1981-11-24 | J. Paul Leblond | Personal repellant device |
| US4356167A (en) | 1978-01-27 | 1982-10-26 | Sandoz, Inc. | Liposome drug delivery systems |
| US4175556A (en) | 1978-04-07 | 1979-11-27 | Freezer Winthrop J | Inhaler with flow-through cap |
| US4196196A (en) | 1978-06-19 | 1980-04-01 | Tiholiz Ivan C | Divalen/monovalent bipolar cation therapy for enhancement of tissue perfusion and reperfusion in disease states |
| US4168002A (en) | 1978-08-03 | 1979-09-18 | Crosby Leslie O | Multiple-seed package card |
| US4272398A (en) | 1978-08-17 | 1981-06-09 | The United States Of America As Represented By The Secretary Of Agriculture | Microencapsulation process |
| DE2840442C2 (de) | 1978-09-16 | 1982-02-11 | C.H. Boehringer Sohn, 6507 Ingelheim | Verwendung des Diketopiperazins L-Leu-L-Trp als Geschmacksstoff für Getränke mit bitterer Geschmacksrichtung |
| DE2849493C2 (de) | 1978-11-15 | 1982-01-14 | Carl Heyer Gmbh, Inhalationstechnik, 5427 Bad Ems | In der Hand zu haltender Aerosolspender |
| USD269463S (en) | 1978-12-08 | 1983-06-21 | Fisons Limited | Container for a medicinal inhaler |
| JPS5837833Y2 (ja) | 1979-04-27 | 1983-08-26 | 凸版印刷株式会社 | アンプル収納容器 |
| JPS6034925B2 (ja) | 1979-07-31 | 1985-08-12 | 帝人株式会社 | 持続性鼻腔用製剤およびその製造法 |
| US4407525A (en) | 1979-10-04 | 1983-10-04 | Gao Gesellschaft Fur Automation Und Organisation Mbh | Identification card with hallmark for authentication by incident and transmitted light |
| GB2072536B (en) | 1980-03-25 | 1983-12-07 | Malem H | Nebuliser |
| US4289759A (en) | 1980-06-23 | 1981-09-15 | Ortho Pharmaceutical Corporation | Immunoregulatory diketopiperazine compounds |
| DE3167658D1 (en) | 1980-12-12 | 1985-01-17 | Combi Co | Inhaler |
| US4900730A (en) | 1981-01-14 | 1990-02-13 | Toyo Jozo Co., Ltd. | Preparation which promotes the absorption of peptides |
| GB2092136B (en) | 1981-01-17 | 1985-06-05 | Mitsui Toatsu Chemicals | Production of n-substituted amide compounds |
| JPS58140026A (ja) | 1982-01-14 | 1983-08-19 | Toyo Jozo Co Ltd | 吸収性良好な製剤 |
| IT1220979B (it) | 1981-06-04 | 1990-06-21 | Lofarma Farma Lab | Capsule contenenti un allergene e procedimento per la loro preparazione |
| SE438261B (sv) | 1981-07-08 | 1985-04-15 | Draco Ab | Anvendning i dosinhalator av ett perforerat membran |
| DE3274065D1 (de) | 1981-07-08 | 1986-12-11 | Draco Ab | Powder inhalator |
| US5260306A (en) | 1981-07-24 | 1993-11-09 | Fisons Plc | Inhalation pharmaceuticals |
| USD276654S (en) | 1981-09-15 | 1984-12-04 | Aktiebolaget Draco | Medical aerosol inhalation device |
| KR890000664B1 (ko) | 1981-10-19 | 1989-03-22 | 바리 안소니 뉴우샘 | 미분된 베클로메타손 디프로피오네이트 일수화물의 제조방법 |
| US4659696A (en) | 1982-04-30 | 1987-04-21 | Takeda Chemical Industries, Ltd. | Pharmaceutical composition and its nasal or vaginal use |
| US4483922A (en) | 1982-05-14 | 1984-11-20 | Amf Inc. | Inactivation of enzymes |
| US4526804A (en) | 1982-08-30 | 1985-07-02 | Ball Corporation | Method for providing sheet metal stock with finely divided powder |
| US4487327A (en) | 1982-12-21 | 1984-12-11 | Grayson Robert E | Locking capsule |
| JPS59163313A (ja) | 1983-03-09 | 1984-09-14 | Teijin Ltd | 経鼻投与用ペプチドホルモン類組成物 |
| AU90762S (en) | 1983-06-29 | 1985-08-15 | Glaxo Group Ltd | Inhaler |
| US4581020A (en) | 1983-07-18 | 1986-04-08 | Trimedyne, Inc. | Medication delivery device and system for percutaneous administration of medication |
| GB8325529D0 (en) | 1983-09-23 | 1983-10-26 | Lilly Industries Ltd | Medicinal forms |
| CH661878A5 (de) | 1983-11-04 | 1987-08-31 | Warner Lambert Co | Kapsel-dosierungsformen. |
| USD295321S (en) | 1984-03-13 | 1988-04-19 | Glaxo Group Limited | Inhaler container for a medical aerosol |
| JPS60248618A (ja) | 1984-05-24 | 1985-12-09 | Nippon Zoki Pharmaceut Co Ltd | ジペプチドを含有する潰瘍治療剤 |
| US4927555A (en) | 1984-08-13 | 1990-05-22 | Colgate-Palmolive Company | Process for making thixotropic detergent compositions |
| USD288852S (en) | 1984-08-29 | 1987-03-17 | Aruman Co., Ltd. | Disposable inhaler |
| US4757066A (en) | 1984-10-15 | 1988-07-12 | Sankyo Company Limited | Composition containing a penem or carbapenem antibiotic and the use of the same |
| IE58468B1 (en) | 1984-10-25 | 1993-09-22 | Warner Lambert Co | Method for sealing capsules and capsule |
| US4592348A (en) | 1984-12-17 | 1986-06-03 | Waters Iv William C | Aerosol inhaler |
| US4946828A (en) | 1985-03-12 | 1990-08-07 | Novo Nordisk A/S | Novel insulin peptides |
| SE448277B (sv) | 1985-04-12 | 1987-02-09 | Draco Ab | Indikeringsanordning vid en doseringsanordning for lekemedel |
| US5785989A (en) | 1985-05-01 | 1998-07-28 | University Utah Research Foundation | Compositions and methods of manufacturing of oral dissolvable medicaments |
| US4615817A (en) | 1985-05-17 | 1986-10-07 | Mccoy Frederic C | Additives containing polytetrafluoroethylene for making stable lubricants |
| CA1318730C (en) | 1985-05-30 | 1993-06-01 | C. Edward Capes | Method of separating carbonaceous components from particulate coal containing inorganic solids and apparatus therefor |
| US5098590A (en) | 1988-02-04 | 1992-03-24 | Colgate Palmolive Co. | Thixotropic aqueous automatic dishwasher detergent compositions with improved stability |
| DE3682457D1 (de) | 1985-07-30 | 1991-12-19 | Glaxo Group Ltd | Geraet zur verabreichung von medikamenten an patienten. |
| AT384552B (de) | 1985-08-01 | 1987-12-10 | Hurka Wilhelm | Inhalationsgeraet zur dosierung und verteilung von festkoerpern in die atemluft |
| US4624861A (en) | 1985-09-05 | 1986-11-25 | Gte Products Corporation | Rare earth oxysulfide phosphors and processes for creating same |
| PT83613B (en) | 1985-10-28 | 1988-11-21 | Lilly Co Eli | Process for the selective chemical removal of a protein amino-terminal residue |
| EP0248051A1 (en) | 1985-11-29 | 1987-12-09 | FISONS plc | Pharmaceutical composition including sodium cromoglycate |
| LU86258A1 (fr) | 1986-01-21 | 1987-09-03 | Rech Dermatologiques C I R D S | Composes benzamido aromatique,leur procede de preparation et leur utilisation en medecine humaine ou veterinaire et en cosmetique |
| SE453566B (sv) | 1986-03-07 | 1988-02-15 | Draco Ab | Anordning vid pulverinhalatorer |
| US4849227A (en) | 1986-03-21 | 1989-07-18 | Eurasiam Laboratories, Inc. | Pharmaceutical compositions |
| US6849708B1 (en) | 1986-05-05 | 2005-02-01 | The General Hospital Corporation | Insulinotropic hormone and uses thereof |
| US5118666A (en) | 1986-05-05 | 1992-06-02 | The General Hospital Corporation | Insulinotropic hormone |
| US5120712A (en) | 1986-05-05 | 1992-06-09 | The General Hospital Corporation | Insulinotropic hormone |
| US5614492A (en) | 1986-05-05 | 1997-03-25 | The General Hospital Corporation | Insulinotropic hormone GLP-1 (7-36) and uses thereof |
| US4926852B1 (en) | 1986-06-23 | 1995-05-23 | Univ Johns Hopkins | Medication delivery system phase one |
| USD301273S (en) | 1986-07-10 | 1989-05-23 | Leonard G Darin | Hand held fly suction device |
| JPS6320301A (ja) | 1986-07-11 | 1988-01-28 | Dainichi Color & Chem Mfg Co Ltd | キトサン微小粒体 |
| US5042975A (en) | 1986-07-25 | 1991-08-27 | Rutgers, The State University Of New Jersey | Iontotherapeutic device and process and iontotherapeutic unit dose |
| EP0257915B1 (en) | 1986-08-11 | 1993-03-10 | Innovata Biomed Limited | Pharmaceutical formulations comprising microcapsules |
| USRE35862E (en) | 1986-08-18 | 1998-07-28 | Emisphere Technologies, Inc. | Delivery systems for pharmacological agents encapsulated with proteinoids |
| EP0545913B1 (en) | 1986-08-18 | 1999-02-24 | Emisphere Technologies, Inc. | Delivery systems for pharmacological agents |
| ES2032831T5 (es) | 1986-08-19 | 2001-02-16 | Genentech Inc | Dispositivo y dispersion para suministro intrapulmonar de factores de crecimiento polipeptidos y citoquinas. |
| DE3639836A1 (de) | 1986-11-21 | 1988-06-01 | Sigrid Bechter | Mundstueck fuer ein inhalationsgeraet |
| KR890003520Y1 (ko) | 1986-12-20 | 1989-05-27 | 주식회사 서흥캅셀 | 의약용 캅셀 |
| US4861627A (en) | 1987-05-01 | 1989-08-29 | Massachusetts Institute Of Technology | Preparation of multiwall polymeric microcapsules |
| US4981295A (en) | 1987-05-11 | 1991-01-01 | City Of Hope | Respiratory training using feedback |
| US6645504B1 (en) | 1987-06-24 | 2003-11-11 | Autoimmune Inc. | Bystander suppression of type I diabetes by oral administration of glucagon |
| DE3727894A1 (de) | 1987-08-21 | 1989-03-02 | Stephan Dieter | Kapsel fuer pharmazeutisch wirksame inhaltsstoffe einer droge |
| GB8723846D0 (en) | 1987-10-10 | 1987-11-11 | Danbiosyst Ltd | Bioadhesive microsphere drug delivery system |
| US4887722A (en) | 1987-12-11 | 1989-12-19 | Greenward Sr Edward H | Method for beneficiating by carbonaceous refuse |
| DE3801326A1 (de) | 1988-01-19 | 1989-07-27 | Asea Brown Boveri | Verfahren zur herstellung einer keramiksuspension |
| US4981625A (en) | 1988-03-14 | 1991-01-01 | California Institute Of Technology | Monodisperse, polymeric microspheres produced by irradiation of slowly thawing frozen drops |
| GB8813338D0 (en) | 1988-06-06 | 1988-07-13 | Osprey Metals Ltd | Powder production |
| USD316902S (en) | 1988-09-02 | 1991-05-14 | Hoelfing H Curt | Meter hose inhaler reservoir |
| GB8821287D0 (en) | 1988-09-12 | 1988-10-12 | Ici Plc | Device |
| EP0360340A1 (en) | 1988-09-19 | 1990-03-28 | Akzo N.V. | Composition for nasal administration containing a peptide |
| USD321570S (en) | 1988-09-30 | 1991-11-12 | Blasdell Richard J | Inhaler |
| ATE104867T1 (de) | 1988-10-04 | 1994-05-15 | Univ Johns Hopkins | Inhalationsgeraet fuer aerosolen. |
| US4984158A (en) | 1988-10-14 | 1991-01-08 | Hillsman Dean | Metered dose inhaler biofeedback training and evaluation system |
| JPH02104531A (ja) | 1988-10-14 | 1990-04-17 | Toyo Jozo Co Ltd | 経鼻投与用生理活性ペプチド組成物 |
| JPH02115154A (ja) | 1988-10-25 | 1990-04-27 | Kao Corp | イミド化合物及びその用途 |
| USD326517S (en) | 1988-10-27 | 1992-05-26 | Glaxo Group Limited | Inhalator |
| JP2692742B2 (ja) | 1988-11-30 | 1997-12-17 | 株式会社ツムラ | 新規なリグナン類 |
| US5006343A (en) | 1988-12-29 | 1991-04-09 | Benson Bradley J | Pulmonary administration of pharmaceutically active substances |
| US5075027A (en) | 1989-02-06 | 1991-12-24 | Colgate Palmolive Co. | Thixotropic aqueous scented automatic dishwasher detergent compositions |
| US5514646A (en) | 1989-02-09 | 1996-05-07 | Chance; Ronald E. | Insulin analogs modified at position 29 of the B chain |
| IT1228460B (it) | 1989-02-23 | 1991-06-19 | Phidea S R L | Inalatore monouso con capsula pre-forata |
| IT1228459B (it) | 1989-02-23 | 1991-06-19 | Phidea S R L | Inalatore con svuotamento regolare e completo della capsula. |
| US4983402A (en) | 1989-02-24 | 1991-01-08 | Clinical Technologies Associates, Inc. | Orally administerable ANF |
| SE466684B (sv) | 1989-03-07 | 1992-03-23 | Draco Ab | Anordning vid en inhalator samt foerfarande foer att med anordningen registrera medicinering med inhalator |
| US5358734A (en) | 1989-03-30 | 1994-10-25 | Gte Products Corporation | Process for producing a blue emitting lamp phosphor |
| US5215739A (en) | 1989-04-05 | 1993-06-01 | Toko Yakuhin Kogyo Kabushiki Kaisha | Spray gel base and spray gel preparation using thereof |
| US4991605A (en) | 1989-04-24 | 1991-02-12 | Philip Morris Incorporated | Container for additive materials for smoking articles |
| US5067500A (en) | 1989-04-24 | 1991-11-26 | Philip Morris Incorporated | Container for additive materials for smoking articles |
| WO1990013327A1 (en) | 1989-04-28 | 1990-11-15 | Riker Laboratories, Inc. | Dry powder inhalation device |
| GB8909891D0 (en) | 1989-04-28 | 1989-06-14 | Riker Laboratories Inc | Device |
| JPH0739339B2 (ja) | 1989-05-01 | 1995-05-01 | アルカーメス コントロールド セラピューティクス,インコーポレイテッド | 生物活性を有する分子の小粒子の製造方法 |
| US5019400A (en) | 1989-05-01 | 1991-05-28 | Enzytech, Inc. | Very low temperature casting of controlled release microspheres |
| US5017383A (en) | 1989-08-22 | 1991-05-21 | Taisho Pharmaceutical Co., Ltd. | Method of producing fine coated pharmaceutical preparation |
| GB8919131D0 (en) | 1989-08-23 | 1989-10-04 | Riker Laboratories Inc | Inhaler |
| US5270305A (en) | 1989-09-08 | 1993-12-14 | Glaxo Group Limited | Medicaments |
| GB8921222D0 (en) | 1989-09-20 | 1989-11-08 | Riker Laboratories Inc | Medicinal aerosol formulations |
| DK544589D0 (da) | 1989-11-01 | 1989-11-01 | Novo Nordisk As | Manuel betjent apparat til dispensering af en forudbestemt maengde af et pulverformet stof |
| WO1991006287A1 (en) | 1989-11-06 | 1991-05-16 | Enzytech, Inc. | Protein microspheres and methods of using them |
| US5188837A (en) | 1989-11-13 | 1993-02-23 | Nova Pharmaceutical Corporation | Lipsopheres for controlled delivery of substances |
| US5105291A (en) | 1989-11-20 | 1992-04-14 | Ricoh Company, Ltd. | Liquid crystal display cell with electrodes of substantially amorphous metal oxide having low resistivity |
| US5131539A (en) | 1989-12-06 | 1992-07-21 | Canon Kabushiki Kaisha | Package for ink jet cartridge |
| USD331106S (en) | 1989-12-30 | 1992-11-17 | Ing. Erich Pfeiffer Gmbh & Co. Kg | Single use inhaler |
| US5545618A (en) | 1990-01-24 | 1996-08-13 | Buckley; Douglas I. | GLP-1 analogs useful for diabetes treatment |
| GB9001635D0 (en) | 1990-01-24 | 1990-03-21 | Ganderton David | Aerosol carriers |
| US5201308A (en) | 1990-02-14 | 1993-04-13 | Newhouse Michael T | Powder inhaler |
| YU48707B (sh) | 1990-03-02 | 1999-07-28 | Glaxo Group Limited | Aparat za inhaliranje - inhalator |
| US6536427B2 (en) | 1990-03-02 | 2003-03-25 | Glaxo Group Limited | Inhalation device |
| SK280968B6 (sk) | 1990-03-02 | 2000-10-09 | Glaxo Group Limited | Balenie medikamentu na použite v inhalačnom prístroji |
| US5615670A (en) | 1990-03-07 | 1997-04-01 | Fisons Plc | Powder inhaler with centrifugal force used to meter powder |
| IT1240750B (it) | 1990-04-12 | 1993-12-17 | Chiesi Farma Spa | Dispositivo per la somministrazione di sostanze medicamentose in polvere |
| JPH05963A (ja) | 1990-04-13 | 1993-01-08 | Toray Ind Inc | ポリペプチド類組成物 |
| US5328464A (en) | 1990-04-24 | 1994-07-12 | Science Incorporated | Closed drug delivery system |
| USD338268S (en) | 1990-05-04 | 1993-08-10 | Omron Corporation | Heating inhaler |
| JPH05507090A (ja) | 1990-05-08 | 1993-10-14 | リポサーム テクノロジー インコーポレイテッド | 直接噴霧乾燥された薬剤/脂質粉末組成物 |
| IL98441A (en) | 1990-06-14 | 1995-12-31 | Rhone Poulenc Rorer Ltd | Powder inhalers |
| DE4021263C2 (de) | 1990-07-04 | 1996-04-11 | Pfeiffer Erich Gmbh & Co Kg | Austragvorrichtung für Medien |
| GB9015522D0 (en) | 1990-07-13 | 1990-08-29 | Braithwaite Philip W | Inhaler |
| US5714167A (en) | 1992-06-15 | 1998-02-03 | Emisphere Technologies, Inc. | Active agent transport systems |
| US5693338A (en) * | 1994-09-29 | 1997-12-02 | Emisphere Technologies, Inc. | Diketopiperazine-based delivery systems |
| US5447728A (en) | 1992-06-15 | 1995-09-05 | Emisphere Technologies, Inc. | Desferrioxamine oral delivery system |
| US5443841A (en) | 1992-06-15 | 1995-08-22 | Emisphere Technologies, Inc. | Proteinoid microspheres and methods for preparation and use thereof |
| US5541155A (en) | 1994-04-22 | 1996-07-30 | Emisphere Technologies, Inc. | Acids and acid salts and their use in delivery systems |
| US5451410A (en) | 1993-04-22 | 1995-09-19 | Emisphere Technologies, Inc. | Modified amino acids for encapsulating active agents |
| US5578323A (en) | 1992-06-15 | 1996-11-26 | Emisphere Technologies, Inc. | Proteinoid carriers and methods for preparation and use thereof |
| US6331318B1 (en) * | 1994-09-30 | 2001-12-18 | Emisphere Technologies Inc. | Carbon-substituted diketopiperazine delivery systems |
| US5629020A (en) | 1994-04-22 | 1997-05-13 | Emisphere Technologies, Inc. | Modified amino acids for drug delivery |
| JPH04103585A (ja) | 1990-08-24 | 1992-04-06 | Nisshin Flour Milling Co Ltd | ピロリジン環を有する化合物 |
| SE9002895D0 (sv) | 1990-09-12 | 1990-09-12 | Astra Ab | Inhalation devices for dispensing powders i |
| US5074418A (en) | 1990-09-12 | 1991-12-24 | Pitney Bowes Inc. | Ink replenishing system transport and storage container |
| EP0640354B1 (en) | 1990-09-26 | 2001-12-05 | Pharmachemie B.V. | Whirl chamber powder inhaler |
| US5170801A (en) | 1990-10-02 | 1992-12-15 | Glaxo Inc. | Medical capsule device actuated by radio-frequency (rf) signal |
| FR2667509B1 (fr) | 1990-10-04 | 1995-08-25 | Valois | Inhalateur a poudre, dispositif de conditionnement de microdoses de poudre sous forme de bandes adaptees a etre utilisees dans un inhalateur a poudre, et procede de fabrication de ces bandes. |
| IL99699A (en) | 1990-10-10 | 2002-04-21 | Autoimmune Inc | Drug with the option of oral, intra-intestinal, or inhaled dosing for suppression of autoimmune response associated with type I diabetes |
| GB9024760D0 (en) | 1990-11-14 | 1991-01-02 | Riker Laboratories Inc | Inhalation device and medicament carrier |
| US5124291A (en) | 1990-11-15 | 1992-06-23 | The Standard Oil Company | Method for deagglomerating and re-exposing catalyst in a fluid bed reactor |
| GB9026191D0 (en) | 1990-12-01 | 1991-01-16 | Harris Pharma Ltd | Breath actuated dispensing device |
| GB9027234D0 (en) | 1990-12-15 | 1991-02-06 | Harris Pharma Ltd | An inhalation device |
| NZ241034A (en) | 1990-12-17 | 1995-03-28 | Minnesota Mining & Mfg | Inhaler device with a dosage control that deactivates an aerosol generator after predetermined time or dosage |
| US5145684A (en) | 1991-01-25 | 1992-09-08 | Sterling Drug Inc. | Surface modified drug nanoparticles |
| GB2253200A (en) | 1991-02-01 | 1992-09-02 | Harris Pharma Ltd | Inhalation apparatus and fracturable capsule for use therewith |
| AU1442592A (en) | 1991-02-20 | 1992-09-15 | Nova Pharmaceutical Corporation | Controlled release microparticulate delivery system for proteins |
| US5208998A (en) | 1991-02-25 | 1993-05-11 | Oyler Jr James R | Liquid substances freeze-drying systems and methods |
| DE69430303T2 (de) | 1991-03-05 | 2002-11-28 | Aradigm Corp | Verfahren und vorrichtung zur korrektur eines nullsignals eines drucksensors fur einen durchflussmesser |
| US5394866A (en) | 1991-03-05 | 1995-03-07 | Aradigm Corporation | Automatic aerosol medication delivery system and methods |
| US5404871A (en) | 1991-03-05 | 1995-04-11 | Aradigm | Delivery of aerosol medications for inspiration |
| USD338062S (en) | 1991-03-06 | 1993-08-03 | Innovata Biomed Limited | Inhaler |
| USD347057S (en) | 1991-03-14 | 1994-05-17 | Technosystem Limited | Inhaler |
| US5797391A (en) | 1991-03-28 | 1998-08-25 | Rhone-Poulenc Rorer Limited | Inhaler |
| US5413804A (en) | 1991-04-23 | 1995-05-09 | Cacique, Inc. | Process for making whey-derived fat substitute product and products thereof |
| US5244653A (en) | 1991-05-01 | 1993-09-14 | Isp Chemicals Inc. | Glycine anhydride dimethylol as a biocide and preservative |
| US6060069A (en) | 1991-05-20 | 2000-05-09 | Dura Pharmaceuticals, Inc. | Pulmonary delivery of pharmaceuticals |
| US5327883A (en) | 1991-05-20 | 1994-07-12 | Dura Pharmaceuticals, Inc. | Apparatus for aerosolizing powdered medicine and process and using |
| US6055980A (en) | 1991-05-20 | 2000-05-02 | Dura Pharmaceuticals, Inc. | Dry powder inhaler |
| US5492112A (en) | 1991-05-20 | 1996-02-20 | Dura Pharmaceuticals, Inc. | Dry powder inhaler |
| FR2676929B1 (fr) | 1991-05-30 | 1994-02-11 | Aerosols Bouchage Ste Fse | Inhalateur de poudres. |
| AU653026B2 (en) | 1991-06-07 | 1994-09-15 | Teikoku Seiyaku Kabushiki Kaisha | Physiologically active polypeptide-containing pharmaceutical composition |
| IT1248059B (it) | 1991-06-14 | 1995-01-05 | Miat Spa | Insufflatore multidose per farmaci in polvere |
| US6681767B1 (en) | 1991-07-02 | 2004-01-27 | Nektar Therapeutics | Method and device for delivering aerosolized medicaments |
| WO1993000951A1 (en) | 1991-07-02 | 1993-01-21 | Inhale, Inc. | Method and device for delivering aerosolized medicaments |
| US5203768A (en) | 1991-07-24 | 1993-04-20 | Alza Corporation | Transdermal delivery device |
| US5337740A (en) | 1991-08-01 | 1994-08-16 | New England Pharmaceuticals, Inc. | Inhalation devices |
| GB9116610D0 (en) | 1991-08-01 | 1991-09-18 | Danbiosyst Uk | Preparation of microparticles |
| US5139878A (en) | 1991-08-12 | 1992-08-18 | Allied-Signal Inc. | Multilayer film constructions |
| EP0528764B1 (en) | 1991-08-16 | 1996-06-12 | Sandoz Ltd. | Inhaler for administration of powdery substances |
| US5287850A (en) | 1991-08-20 | 1994-02-22 | Habley Medical Technology Corporation | Timing and velocity controlled powered pharmaceutical inhaler |
| US6029661A (en) | 1991-08-26 | 2000-02-29 | 3M Innovative Properties Company | Powder dispenser |
| USD337636S (en) | 1991-09-12 | 1993-07-20 | Devilbiss Health Care, Inc. | Ultrasonic medicament nebulizer |
| US5167506A (en) | 1991-10-24 | 1992-12-01 | Minnesota Mining And Manufacturing Company | Inhalation device training system |
| USD348100S (en) | 1991-10-29 | 1994-06-21 | Fisons Plc | Medicament inhaler |
| USD350602S (en) | 1991-11-01 | 1994-09-13 | Rhone-Poulenc Rorer Limited | Combined dry powder inhaler and cap |
| US6063910A (en) | 1991-11-14 | 2000-05-16 | The Trustees Of Princeton University | Preparation of protein microparticles by supercritical fluid precipitation |
| USD350821S (en) | 1991-11-18 | 1994-09-20 | Smithkline Beecham P.L.C. | Oral inhaler |
| SE9103572D0 (sv) | 1991-11-29 | 1991-11-29 | Astra Ab | Organic salts of n,n'-diacetyl cystine |
| USD340975S (en) | 1991-12-02 | 1993-11-02 | Thayer Medical Corporation | Combined expansion chamber metered dose inhaler dispenser and adaptor |
| US5338837A (en) | 1991-12-13 | 1994-08-16 | The Trustees Of Princeton University | Glycosylated steroid derivatives for transport across biological membranes and process for making same |
| DE4211475A1 (de) | 1991-12-14 | 1993-06-17 | Asta Medica Ag | Pulverinhalator |
| JP3121080B2 (ja) | 1991-12-19 | 2000-12-25 | アール・ピー・シーラー コーポレイション | カプセル封入用溶液 |
| GB2262452B (en) | 1991-12-19 | 1995-12-20 | Minnesota Mining & Mfg | Inhalation device |
| US5363842A (en) | 1991-12-20 | 1994-11-15 | Circadian, Inc. | Intelligent inhaler providing feedback to both patient and medical professional |
| US5525519A (en) | 1992-01-07 | 1996-06-11 | Middlesex Sciences, Inc. | Method for isolating biomolecules from a biological sample with linear polymers |
| US5320094A (en) | 1992-01-10 | 1994-06-14 | The Johns Hopkins University | Method of administering insulin |
| EP0621774B1 (en) | 1992-01-21 | 1996-12-18 | Sri International | Improved process for preparing micronized polypeptide drugs |
| DE9209050U1 (de) | 1992-02-13 | 1992-10-01 | Schrader, Barthold von, 2400 Travemünde | Inhalationseinrichtung |
| US5476093A (en) | 1992-02-14 | 1995-12-19 | Huhtamaki Oy | Device for more effective pulverization of a powdered inhalation medicament |
| US5469971A (en) | 1992-02-26 | 1995-11-28 | Estee Lauder Inc. | Method and apparatus for deagglomerating powder |
| EP0558879B1 (en) | 1992-03-04 | 1997-05-14 | Astra Aktiebolag | Disposable inhaler |
| US5639441A (en) | 1992-03-06 | 1997-06-17 | Board Of Regents Of University Of Colorado | Methods for fine particle formation |
| US5352461A (en) | 1992-03-11 | 1994-10-04 | Pharmaceutical Discovery Corporation | Self assembling diketopiperazine drug delivery system |
| DK36392D0 (da) | 1992-03-19 | 1992-03-19 | Novo Nordisk As | Anvendelse af kemisk forbindelse |
| USD348929S (en) | 1992-04-03 | 1994-07-19 | Norton Healthcare Limited | Medicament inhaler |
| CA2096302A1 (en) | 1992-05-15 | 1993-11-16 | David Kilis | Air flow controller and recording system |
| USD345013S (en) | 1992-06-11 | 1994-03-08 | Schering Corporation | Combined inhaler and cover |
| USD350193S (en) | 1992-06-11 | 1994-08-30 | Schering Corporation | Combined inhaler and cover |
| USD344796S (en) | 1992-06-11 | 1994-03-01 | Schering Corporation | Combined inhaler and cover |
| USD344797S (en) | 1992-06-11 | 1994-03-01 | Schering Corporation | Combined inhaler and cover |
| CA2115444C (en) | 1992-06-12 | 2000-10-03 | Yuji Makino | Preparation for intratracheobronchial administration |
| US5811127A (en) | 1992-06-15 | 1998-09-22 | Emisphere Technologies, Inc. | Desferrioxamine oral delivery system |
| US5792451A (en) | 1994-03-02 | 1998-08-11 | Emisphere Technologies, Inc. | Oral drug delivery compositions and methods |
| US5394868A (en) | 1992-06-25 | 1995-03-07 | Schering Corporation | Inhalation device for powdered medicaments |
| GB9213874D0 (en) | 1992-06-30 | 1992-08-12 | Fisons Plc | Process to novel medicament form |
| US5785049A (en) | 1994-09-21 | 1998-07-28 | Inhale Therapeutic Systems | Method and apparatus for dispersion of dry powder medicaments |
| US6509006B1 (en) | 1992-07-08 | 2003-01-21 | Inhale Therapeutic Systems, Inc. | Devices compositions and methods for the pulmonary delivery of aerosolized medicaments |
| US6582728B1 (en) | 1992-07-08 | 2003-06-24 | Inhale Therapeutic Systems, Inc. | Spray drying of macromolecules to produce inhaleable dry powders |
| GB9214819D0 (en) | 1992-07-13 | 1992-08-26 | Minnesota Mining & Mfg | Valve assemblies |
| GB9216038D0 (en) | 1992-07-28 | 1992-09-09 | Bespak Plc | Dispensing apparatus for powdered medicaments |
| GB2269992A (en) | 1992-08-14 | 1994-03-02 | Rh Ne Poulenc Rorer Limited | Powder inhalation formulations |
| GB2270293A (en) | 1992-09-05 | 1994-03-09 | Medix Ltd | Drug dispensing system |
| USD348928S (en) | 1992-09-21 | 1994-07-19 | Schering Corporation | Inhaler |
| US5333106A (en) | 1992-10-09 | 1994-07-26 | Circadian, Inc. | Apparatus and visual display method for training in the power use of aerosol pharmaceutical inhalers |
| AU5171293A (en) | 1992-10-14 | 1994-05-09 | Regents Of The University Of Colorado, The | Ion-pairing of drugs for improved efficacy and delivery |
| CA2147260C (en) | 1992-10-19 | 1999-04-13 | Mark Bernard Mecikalski | Dry powder inhaler |
| AU121578S (en) | 1992-10-22 | 1994-09-20 | Fisons Plc | An inhalation device |
| USD359555S (en) | 1992-11-18 | 1995-06-20 | Nippon Glaxo Limited | Nasal medicine inhaler |
| USD352107S (en) | 1992-12-10 | 1994-11-01 | Ciba-Geigy Corporation | Inhaler |
| USD349572S (en) | 1992-12-10 | 1994-08-09 | Schering Corporation | Aerosol inhaler |
| US6250300B1 (en) | 1992-12-11 | 2001-06-26 | Ab Astra | System for dispensing pharmaceutically active compounds |
| SE9203743D0 (sv) | 1992-12-11 | 1992-12-11 | Astra Ab | Efficient use |
| WO1994014492A2 (en) | 1992-12-18 | 1994-07-07 | Schering Corporation | Inhaler for powdered medications |
| US5401516A (en) | 1992-12-21 | 1995-03-28 | Emisphere Technologies, Inc. | Modified hydrolyzed vegetable protein microspheres and methods for preparation and use thereof |
| US6880554B1 (en) | 1992-12-22 | 2005-04-19 | Battelle Memorial Institute | Dispensing device |
| US6105571A (en) | 1992-12-22 | 2000-08-22 | Electrosols, Ltd. | Dispensing device |
| US5896855A (en) | 1992-12-24 | 1999-04-27 | Rhone-Poulenc Rorer Limited | Multi dose inhaler apparatus |
| FR2700279B1 (fr) | 1993-01-14 | 1995-03-17 | Valois | Dispositif portatif pour projeter des doses d'une substance fluide à l'aide d'un flux d'air comprimé. |
| AU119600S (en) | 1993-01-21 | 1994-03-07 | Boehringer Ingelheim Kg | Inhaler device |
| US7448375B2 (en) | 1993-01-29 | 2008-11-11 | Aradigm Corporation | Method of treating diabetes mellitus in a patient |
| US5364838A (en) | 1993-01-29 | 1994-11-15 | Miris Medical Corporation | Method of administration of insulin |
| US5672581A (en) | 1993-01-29 | 1997-09-30 | Aradigm Corporation | Method of administration of insulin |
| US6024090A (en) | 1993-01-29 | 2000-02-15 | Aradigm Corporation | Method of treating a diabetic patient by aerosolized administration of insulin lispro |
| US6131567A (en) * | 1993-01-29 | 2000-10-17 | Aradigm Corporation | Method of use of monomeric insulin as a means for improving the reproducibility of inhaled insulin |
| US5888477A (en) | 1993-01-29 | 1999-03-30 | Aradigm Corporation | Use of monomeric insulin as a means for improving the bioavailability of inhaled insulin |
| US5441060A (en) | 1993-02-08 | 1995-08-15 | Duke University | Dry powder delivery system |
| IL108780A (en) | 1993-02-27 | 1999-06-20 | Fisons Plc | Inhalation device |
| US5437271A (en) | 1993-04-06 | 1995-08-01 | Minnesota Mining And Manufacturing Company | Deagglomerators for dry powder inhalers |
| US5372128A (en) | 1993-04-14 | 1994-12-13 | Habley Medical Technology Corporation | Fluidizing powder inhaler |
| ZA939608B (en) | 1993-04-22 | 1994-08-24 | Emisphere Tech Inc | Modified hydrolyzed vegetable protein microspheres and methods for preparation and use thereof. |
| ATE204467T1 (de) | 1993-04-22 | 2001-09-15 | Emisphere Tech Inc | Orale darreichungsform |
| US5643957A (en) | 1993-04-22 | 1997-07-01 | Emisphere Technologies, Inc. | Compounds and compositions for delivering active agents |
| US5360614A (en) * | 1993-04-26 | 1994-11-01 | The Estee Corporation | Method of controlling the release of carbohydrates by encapsulation and composition therefor |
| AU679986B2 (en) | 1993-04-28 | 1997-07-17 | N.V. Organon | Lyospheres comprising gonadotropin |
| KR100244690B1 (ko) | 1993-05-12 | 2000-02-15 | 야스이 쇼사꾸 | 분말상 약제 멀티도스 시약장치 |
| US5424286A (en) | 1993-05-24 | 1995-06-13 | Eng; John | Exendin-3 and exendin-4 polypeptides, and pharmaceutical compositions comprising same |
| US5533502A (en) | 1993-05-28 | 1996-07-09 | Vortran Medical Technology, Inc. | Powder inhaler with aerosolization occurring within each individual powder receptacle |
| USD365876S (en) | 1993-06-16 | 1996-01-02 | Chawla Brindra P S | Medicament inhaler |
| US5747445A (en) | 1993-06-24 | 1998-05-05 | Astra Aktiebolag | Therapeutic preparation for inhalation |
| IS1796B (is) | 1993-06-24 | 2001-12-31 | Ab Astra | Fjölpeptíð lyfjablanda til innöndunar sem einnig inniheldur eykjaefnasamband |
| TW402506B (en) | 1993-06-24 | 2000-08-21 | Astra Ab | Therapeutic preparation for inhalation |
| US6632456B1 (en) | 1993-06-24 | 2003-10-14 | Astrazeneca Ab | Compositions for inhalation |
| US6794357B1 (en) | 1993-06-24 | 2004-09-21 | Astrazeneca Ab | Compositions for inhalation |
| US5506203C1 (en) * | 1993-06-24 | 2001-02-06 | Astra Ab | Systemic administration of a therapeutic preparation |
| US5562909A (en) | 1993-07-12 | 1996-10-08 | Massachusetts Institute Of Technology | Phosphazene polyelectrolytes as immunoadjuvants |
| GB9314614D0 (en) | 1993-07-14 | 1993-08-25 | Minnesota Mining & Mfg | Dry powder inhalers |
| US5371046A (en) | 1993-07-22 | 1994-12-06 | Taiwan Semiconductor Manufacturing Company | Method to solve sog non-uniformity in the VLSI process |
| JPH0741428A (ja) | 1993-07-30 | 1995-02-10 | Teijin Ltd | ペプチド、蛋白質性薬物経鼻・経肺製剤 |
| US5727546A (en) | 1993-08-18 | 1998-03-17 | Fisons Plc | Powder inhaler with breath flow regulation valve |
| US5306453A (en) | 1993-08-18 | 1994-04-26 | Edward Shulman | Apparatus and method of making a non-woven fabric |
| US5524613A (en) | 1993-08-25 | 1996-06-11 | Habley Medical Technology Corporation | Controlled multi-pharmaceutical inhaler |
| BE1007551A3 (nl) | 1993-09-24 | 1995-08-01 | Philips Electronics Nv | Werkwijze voor het in een rekenmachine automatisch herstellen van consistentie in een hierarchische objektstruktuur na een interaktie door een gebruiker en rekenmachine voorzien van zo een systeem voor automatische consistentieherstelling. |
| US5477285A (en) | 1993-10-06 | 1995-12-19 | Thomson Consumer Electronics, Inc. | CRT developing apparatus |
| GB9322014D0 (en) | 1993-10-26 | 1993-12-15 | Co Ordinated Drug Dev | Improvements in and relating to carrier particles for use in dry powder inhalers |
| US5726156A (en) | 1995-03-06 | 1998-03-10 | Trega Biosciences, Inc. | Cytokine regulatory agents and methods of use in pathologies and conditions associated with altered cytokine levels |
| PT729351E (pt) | 1993-11-16 | 2000-12-29 | Skyepharma Inc | Vesiculas com libertacao controlada de activos |
| EP0655237A1 (de) | 1993-11-27 | 1995-05-31 | Hoechst Aktiengesellschaft | Medizinische Aerosolformulierung |
| USD358880S (en) | 1993-12-02 | 1995-05-30 | Tenax Corporation | Dry powder inhalator |
| US5705483A (en) | 1993-12-09 | 1998-01-06 | Eli Lilly And Company | Glucagon-like insulinotropic peptides, compositions and methods |
| DE4422710C1 (de) | 1994-06-29 | 1995-09-14 | Boehringer Ingelheim Kg | Inhalationsgerät mit einem Elektronikmodul zur Funktionsüberwachung |
| CA2179202C (en) | 1993-12-18 | 2006-06-06 | Stephen William Eason | Powder inhalator |
| USD357603S (en) | 1993-12-20 | 1995-04-25 | Wolff Stephen H | Base for displaying or holding items |
| US5415162A (en) | 1994-01-18 | 1995-05-16 | Glaxo Inc. | Multi-dose dry powder inhalation device |
| US5484606A (en) | 1994-01-24 | 1996-01-16 | The Procter & Gamble Company | Process for reducing the precipitation of difficulty soluble pharmaceutical actives |
| PT101450B (pt) | 1994-02-02 | 1999-11-30 | Hovione Produtos Farmaceuticos | Novo dispositivo para inalacao |
| WO1995022036A1 (en) | 1994-02-09 | 1995-08-17 | Kinerton Limited | Process for drying a material from solution |
| SE9400462D0 (sv) | 1994-02-11 | 1994-02-11 | Astra Ab | Filling device |
| US6051256A (en) | 1994-03-07 | 2000-04-18 | Inhale Therapeutic Systems | Dispersible macromolecule compositions and methods for their preparation and use |
| NZ281112A (en) | 1994-03-07 | 1998-04-27 | Inhale Therapeutic Syst | Powdered insulin delivered as an aerosol |
| US5505194A (en) | 1994-03-23 | 1996-04-09 | Abbott Laboratories | Aerosol inhalation device having slideably and rotatably connected elliptical cylinder portions |
| AU124387S (en) | 1994-03-25 | 1995-08-11 | Astra Ab | Training device for an inhaler |
| US5839429A (en) | 1994-03-25 | 1998-11-24 | Astra Aktiebolag | Method and apparatus in connection with an inhaler |
| DK0677263T3 (da) | 1994-04-15 | 1997-10-06 | Fissler Gmbh | Stege- og/eller kogeredskab, der er indrettet til en tilførsel af varmeenergi fra bundsiden ved varmeledning eller ved elektromagnetisk induktion |
| US6395744B1 (en) | 1994-04-22 | 2002-05-28 | Queen's University At Kingston | Method and compositions for the treatment or amelioration of female sexual dysfunction |
| FI942196L (fi) | 1994-05-11 | 1995-11-12 | Orion Yhtymae Oy | Jauheinhalaattori |
| ES2245780T3 (es) | 1994-05-18 | 2006-01-16 | Nektar Therapeutics | Metodos y composiciones para la formulacion de interferones como un polvo seco. |
| WO1995031979A1 (en) | 1994-05-19 | 1995-11-30 | R.P. Scherer International Corporation | Solutions of aryl or heteroaryl substituted alkanoic acids in lipophilic solvents and soft gelatin capsules containing such solutions |
| US5483954A (en) | 1994-06-10 | 1996-01-16 | Mecikalski; Mark B. | Inhaler and medicated package |
| IL110024A (en) | 1994-06-15 | 1998-04-05 | Yissum Res Dev Co | Controlled release oral drug delivery system containing hydrogel- forming polymer |
| USD363775S (en) | 1994-06-21 | 1995-10-31 | Rhone-Poulenc Rorer Limited | Multidose dry powder inhaler |
| USD362500S (en) | 1994-06-28 | 1995-09-19 | Thayer Medical Corporation | Medication inhaler spacer |
| US5641510A (en) | 1994-07-01 | 1997-06-24 | Genentech, Inc. | Method for treating capsules used for drug storage |
| US6039208A (en) | 1994-07-29 | 2000-03-21 | Ortho Pharmaceutical Corporation | Variable day start tablet dispenser |
| US5562231A (en) | 1994-07-29 | 1996-10-08 | Ortho Pharmaceutical Corporation | Variable day start tablet dispenser |
| US5623724A (en) | 1994-08-09 | 1997-04-22 | Northrop Grumman Corporation | High power capacitor |
| GB9416884D0 (en) | 1994-08-20 | 1994-10-12 | Danbiosyst Uk | Drug delivery compositions |
| USD359153S (en) | 1994-08-25 | 1995-06-13 | Viggiano Bernard J | Muffin top |
| US5574008A (en) | 1994-08-30 | 1996-11-12 | Eli Lilly And Company | Biologically active fragments of glucagon-like insulinotropic peptide |
| US5547929A (en) * | 1994-09-12 | 1996-08-20 | Eli Lilly And Company | Insulin analog formulations |
| CZ289029B6 (cs) | 1994-09-21 | 2001-10-17 | Inhale Therapeutic Systems | Způsob aerosolizace práąku, zejména práąkového léku a zařízení k provádění tohoto způsobu |
| FR2725626A1 (fr) | 1994-10-18 | 1996-04-19 | Sofab | Dispositif pour l'inhalation de produits en poudre |
| AU4010395A (en) | 1994-10-27 | 1996-05-23 | Amgen, Inc. | Compositions for increased bioavailability of orally delivered therapeutic agents |
| SE9404140D0 (sv) | 1994-11-29 | 1994-11-29 | Astra Ab | Dose indicating device |
| US5877174A (en) | 1994-12-01 | 1999-03-02 | Toyama Chemical Co., Ltd. | 2,3-diketopiperazine derivatives or their salts |
| SE9404439D0 (sv) | 1994-12-21 | 1994-12-21 | Astra Ab | Inhalation device |
| AR002009A1 (es) | 1994-12-22 | 1998-01-07 | Astra Ab | Composicion farmaceutica, procedimiento para la manufactura de un polvo de proliposoma como el utilizado en dicha composicion, procedimiento para lamanufactura de dicha composicion, uso de dicha composicion farmaceutica en la manufactura de un medicamento y dispositivo inhalador de polvo seco. |
| US6485726B1 (en) | 1995-01-17 | 2002-11-26 | The Brigham And Women's Hospital, Inc. | Receptor specific transepithelial transport of therapeutics |
| KR100390480B1 (ko) | 1995-01-23 | 2003-10-04 | 디렉트-할러 아/에스 | 흡입기 |
| USD368364S (en) | 1995-02-02 | 1996-04-02 | Reitano Joseph R | Inhaler case |
| US5901703A (en) | 1995-02-06 | 1999-05-11 | Unisia Jecs Corporation | Medicine administering device for nasal cavities |
| US5660835A (en) | 1995-02-24 | 1997-08-26 | East Carolina University | Method of treating adenosine depletion |
| EP0870699A3 (en) | 1995-03-10 | 1998-10-21 | Minnesota Mining And Manufacturing Company | Aerosol valves |
| US5653961A (en) | 1995-03-31 | 1997-08-05 | Minnesota Mining And Manufacturing Company | Butixocort aerosol formulations in hydrofluorocarbon propellant |
| US5542539A (en) | 1995-04-04 | 1996-08-06 | Ethicon Endo-Surgery, Inc. | Container for quick release packages for surgical instruments |
| USD377215S (en) | 1995-04-13 | 1997-01-07 | Glaxo Group Limited | Inhaler |
| US5990077A (en) | 1995-04-14 | 1999-11-23 | 1149336 Ontario Inc. | Glucagon-like peptide-2 and its therapeutic use |
| US6309671B1 (en) | 1995-04-14 | 2001-10-30 | Inhale Therapeutic Systems | Stable glassy state powder formulations |
| US5645051A (en) | 1995-04-21 | 1997-07-08 | Dura Pharmaceuticals, Inc. | Unit dose dry powder inhaler |
| US5622166A (en) | 1995-04-24 | 1997-04-22 | Dura Pharmaceuticals, Inc. | Dry powder inhaler delivery system |
| US5921237A (en) | 1995-04-24 | 1999-07-13 | Dura Pharmaceuticals, Inc. | Dry powder inhaler |
| US6428771B1 (en) | 1995-05-15 | 2002-08-06 | Pharmaceutical Discovery Corporation | Method for drug delivery to the pulmonary system |
| US5922253A (en) | 1995-05-18 | 1999-07-13 | Alkermes Controlled Therapeutics, Inc. | Production scale method of forming microparticles |
| US5809997A (en) | 1995-05-18 | 1998-09-22 | Medtrac Technologies, Inc. | Electronic medication chronolog device |
| US5924419A (en) | 1995-05-22 | 1999-07-20 | Kotliar; Igor K. | Apparatus for passive hypoxic training and therapy |
| DE19519840A1 (de) | 1995-05-31 | 1996-12-05 | Kaewert Klaus | Gelantinekapsel |
| AU128811S (en) | 1995-06-06 | 1996-12-03 | Orion Yhtymae Oy | A protective cover for example a moisture protective cover for a powder inhaler |
| US5714007A (en) | 1995-06-06 | 1998-02-03 | David Sarnoff Research Center, Inc. | Apparatus for electrostatically depositing a medicament powder upon predefined regions of a substrate |
| US5641861A (en) | 1995-06-07 | 1997-06-24 | Torrey Pines Institute For Molecular Studies | μopioid receptor ligands: agonists and antagonists |
| US5824345A (en) | 1995-06-07 | 1998-10-20 | Emisphere Technologies, Inc. | Fragrances and flavorants |
| US5919897A (en) | 1995-06-07 | 1999-07-06 | Torrey Pines Institute For Molecular Studies | MU opioid receptor ligands: agonists and antagonists |
| US5610271A (en) | 1995-06-07 | 1997-03-11 | Torrey Pines Institute For Molecular Studies | Kappa receptor selective opioid peptides |
| US6193844B1 (en) | 1995-06-07 | 2001-02-27 | Mclaughlin John R. | Method for making paper using microparticles |
| US6357442B1 (en) | 1995-06-08 | 2002-03-19 | Innovative Devices, Llc | Inhalation actuated device for use with metered dose inhalers (MDIS) |
| US6672304B1 (en) | 1995-06-08 | 2004-01-06 | Innovative Devices, Llc | Inhalation actuated device for use with metered dose inhalers (MDIs) |
| PT837710E (pt) | 1995-06-21 | 2002-05-31 | Sofotec Gmbh & Co Kg | Cartucho de po farmaceutico com dispositivo de doseamento integrado e inalador para medicamentos em po |
| GB9513218D0 (en) | 1995-06-29 | 1995-09-06 | Fisons Plc | Inhalation device and method |
| DE19523516C1 (de) | 1995-06-30 | 1996-10-31 | Asta Medica Ag | Inhalator zum Verabreichen von Medikamenten aus Blisterpackungen |
| AU131838S (en) | 1995-07-01 | 1997-10-21 | Glaxo Group Ltd | Inhalation device |
| JP3098401B2 (ja) | 1995-07-12 | 2000-10-16 | 株式会社エルティーティー研究所 | 経鼻投与用製剤 |
| US5758638A (en) | 1995-07-24 | 1998-06-02 | Kreamer; Jeffry W. | Indicator for a medicament inhaler |
| US5642727A (en) | 1995-07-25 | 1997-07-01 | David Sarnoff Research Center, Inc. | Inhaler apparatus using a tribo-electric charging technique |
| WO1997004747A1 (en) | 1995-07-27 | 1997-02-13 | Dunn James M | Drug delivery systems for macromolecular drugs |
| US6209538B1 (en) | 1995-08-02 | 2001-04-03 | Robert A. Casper | Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament |
| SE9502800D0 (sv) | 1995-08-10 | 1995-08-10 | Astra Ab | Disposable inhaler |
| SE9502799D0 (sv) | 1995-08-10 | 1995-08-10 | Astra Ab | Device in inhalers |
| JP3317823B2 (ja) | 1995-08-11 | 2002-08-26 | 株式会社ユニシアジェックス | 投薬器 |
| US5980865A (en) | 1995-08-18 | 1999-11-09 | Baker Norton Pharmaceuticals, Inc. | Method for treating late phase allergic reactions and inflammatory diseases |
| US5690910A (en) | 1995-08-18 | 1997-11-25 | Baker Norton Pharmaceuticals, Inc. | Method for treating asthma |
| US5746197A (en) | 1995-08-18 | 1998-05-05 | Williams; Jeffery W. | Extension for metered dose inhaler |
| US6852690B1 (en) | 1995-08-22 | 2005-02-08 | Amylin Pharmaceuticals, Inc. | Method and composition for enhanced parenteral nutrition |
| FR2738153B1 (fr) | 1995-09-04 | 1998-01-02 | Valois | Appareil d'inhalation destine a distribuer des doses precises et reproductibles de produit pulverulent |
| US5617844A (en) | 1995-09-21 | 1997-04-08 | King; Russell W. | Aerosol medication delivery system |
| KR0124764Y1 (ko) | 1995-09-23 | 1998-09-15 | 양주환 | 의약 및 식품용 하드 공 캅셀 |
| SE9503344D0 (sv) | 1995-09-27 | 1995-09-27 | Astra Ab | Inhalation device |
| US5766620A (en) | 1995-10-23 | 1998-06-16 | Theratech, Inc. | Buccal delivery of glucagon-like insulinotropic peptides |
| US5849322A (en) | 1995-10-23 | 1998-12-15 | Theratech, Inc. | Compositions and methods for buccal delivery of pharmaceutical agents |
| WO1997017945A2 (en) | 1995-11-13 | 1997-05-22 | Minimed, Inc. | Methods and compositions for the delivery of monomeric proteins |
| DE19545257A1 (de) | 1995-11-24 | 1997-06-19 | Schering Ag | Verfahren zur Herstellung von morphologisch einheitlichen Mikrokapseln sowie nach diesem Verfahren hergestellte Mikrokapseln |
| DE59605366D1 (de) | 1995-12-07 | 2000-07-06 | Jago Pharma Ag Muttenz | Inhalator zur mehrfachen dosisweisen abgabe eines pharmakologischen trockenpulvers |
| US7131441B1 (en) | 1995-12-07 | 2006-11-07 | Skyepharma Ag | Inhaler for multiple dosed administration of a pharmacological dry powder |
| JP2000503565A (ja) | 1996-01-03 | 2000-03-28 | グラクソ、グループ、リミテッド | 吸入装置 |
| US6026809A (en) | 1996-01-25 | 2000-02-22 | Microdose Technologies, Inc. | Inhalation device |
| US6470884B2 (en) | 1996-01-29 | 2002-10-29 | Aventis Pharma Limited | Capsule opening arrangement for use in a powder inhaler |
| JPH09208485A (ja) | 1996-01-31 | 1997-08-12 | Teijin Ltd | ペプチド・蛋白質性薬物の水難溶性組成物 |
| DE69703649T2 (de) | 1996-02-06 | 2001-08-02 | E.I. Du Pont De Nemours And Co., Wilmington | Behandlung von deagglomerierten teilchen mit plasmaaktivierter spezies |
| USD381416S (en) | 1996-02-08 | 1997-07-22 | Astra Aktiebolag | Unit dose inhaler |
| PT883415E (pt) | 1996-02-21 | 2002-10-31 | Schering Corp | Inalador para medicacao em po |
| USD377861S (en) | 1996-02-21 | 1997-02-11 | Medport, Inc. | Inhaler carrying case |
| ATE247456T1 (de) | 1996-02-27 | 2003-09-15 | Teijin Ltd | Puderförmige zusammensetzung zur nasalen anwendung |
| US6509313B1 (en) | 1996-02-28 | 2003-01-21 | Cornell Research Foundation, Inc. | Stimulation of immune response with low doses of cytokines |
| US5699789A (en) | 1996-03-11 | 1997-12-23 | Hendricks; Mark R. | Dry powder inhaler |
| JP3328132B2 (ja) | 1996-03-21 | 2002-09-24 | 株式会社ユニシアジェックス | 吸入式投薬器 |
| GB9606188D0 (en) | 1996-03-23 | 1996-05-29 | Danbiosyst Uk | Pollysaccharide microspheres for the pulmonary delivery of drugs |
| USD395499S (en) | 1996-04-08 | 1998-06-23 | Dura Pharmaceuticals, Inc. | Dry powder inhaler |
| US5875776A (en) | 1996-04-09 | 1999-03-02 | Vivorx Pharmaceuticals, Inc. | Dry powder inhaler |
| US5858099A (en) | 1996-04-09 | 1999-01-12 | Sarnoff Corporation | Electrostatic chucks and a particle deposition apparatus therefor |
| HUP9901575A3 (en) | 1996-04-29 | 1999-11-29 | Dura Pharmaceuticals Inc San D | Methods of dry powder inhalation |
| US5817343A (en) | 1996-05-14 | 1998-10-06 | Alkermes, Inc. | Method for fabricating polymer-based controlled-release devices |
| AU132977S (en) | 1996-05-17 | 1998-02-17 | Astrazeneca Ab | Container for inhaling apparatus |
| US5985309A (en) | 1996-05-24 | 1999-11-16 | Massachusetts Institute Of Technology | Preparation of particles for inhalation |
| US6254854B1 (en) | 1996-05-24 | 2001-07-03 | The Penn Research Foundation | Porous particles for deep lung delivery |
| USRE37053E1 (en) | 1996-05-24 | 2001-02-13 | Massachusetts Institute Of Technology | Particles incorporating surfactants for pulmonary drug delivery |
| US5874064A (en) | 1996-05-24 | 1999-02-23 | Massachusetts Institute Of Technology | Aerodynamically light particles for pulmonary drug delivery |
| US6503480B1 (en) | 1997-05-23 | 2003-01-07 | Massachusetts Institute Of Technology | Aerodynamically light particles for pulmonary drug delivery |
| JPH1053765A (ja) | 1996-06-04 | 1998-02-24 | Denso Corp | スメクチック液晶組成物及び液晶セル |
| ATE510552T1 (de) | 1996-06-05 | 2011-06-15 | Basil Rapoport | Verfahren zur herstellung von sekretierte verkurzte varianten des humanen thyrotropinrezeptors |
| US5871010A (en) | 1996-06-10 | 1999-02-16 | Sarnoff Corporation | Inhaler apparatus with modified surfaces for enhanced release of dry powders |
| AUPO066096A0 (en) | 1996-06-26 | 1996-07-18 | Peptide Delivery Systems Pty Ltd | Oral delivery of peptides |
| US5769276A (en) | 1996-07-10 | 1998-06-23 | Terronics Development Corporation | Powder atomizer |
| US5783556A (en) | 1996-08-13 | 1998-07-21 | Genentech, Inc. | Formulated insulin-containing composition |
| AU133903S (en) | 1996-08-19 | 1998-05-29 | Orion Yhtymae Oy | Inhaler device |
| US6277819B1 (en) | 1996-08-30 | 2001-08-21 | Eli Lilly And Company | Use of GLP-1 or analogs in treatment of myocardial infarction |
| US6006753A (en) | 1996-08-30 | 1999-12-28 | Eli Lilly And Company | Use of GLP-1 or analogs to abolish catabolic changes after surgery |
| JP3890099B2 (ja) | 1996-09-30 | 2007-03-07 | キヤノン株式会社 | パターン認識装置及びその方法、及びそのプログラムを記憶した記憶媒体 |
| JP3020141B2 (ja) | 1996-10-07 | 2000-03-15 | 株式会社富士薬品 | 経鼻投与用製剤 |
| US6532437B1 (en) | 1996-10-23 | 2003-03-11 | Cornell Research Foundation, Inc. | Crystalline frap complex |
| UA65549C2 (uk) | 1996-11-05 | 2004-04-15 | Елі Ліллі Енд Компані | Спосіб регулювання ожиріння шляхом периферійного введення аналогів та похідних glp-1 (варіанти) та фармацевтична композиція |
| US6441172B1 (en) | 1996-11-07 | 2002-08-27 | Torrey Pines Institute For Molecular Studies | Diketodiazacyclic compounds, diazacyclic compounds and combinatorial libraries thereof |
| JP2001504105A (ja) | 1996-11-12 | 2001-03-27 | ノボ ノルディスク アクティーゼルスカブ | Glp―1ペプチドの利用 |
| DE19647947A1 (de) | 1996-11-20 | 1998-05-28 | Pfeiffer Erich Gmbh & Co Kg | Austragvorrichtung für Medien |
| US5868774A (en) | 1996-11-21 | 1999-02-09 | Reil; Vladimir | Unique cartridge and earring stud gun system |
| US6159360A (en) | 1996-11-22 | 2000-12-12 | Heinkel Industriezentrifugen Gmbh & Co. | Invertible filter centrifuge including a solids drier |
| ES2175491T3 (es) | 1996-12-11 | 2002-11-16 | Earth Sciences Ltd | Procedimiento y aparato para la transformacion y tratamiento de material en particulas. |
| USD390651S (en) | 1996-12-12 | 1998-02-10 | Inhale Therapeutics Systems | Medicament inhaler housing |
| GB9626233D0 (en) | 1996-12-18 | 1997-02-05 | Chawla Brinda P S | Medicament packaging and deliveery device |
| GB9626263D0 (en) | 1996-12-18 | 1997-02-05 | Innovata Biomed Ltd | Powder inhaler |
| GB2320489A (en) | 1996-12-20 | 1998-06-24 | Norton Healthcare Ltd | Inhaler dose counter |
| US6077543A (en) | 1996-12-31 | 2000-06-20 | Inhale Therapeutic Systems | Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients |
| USD397435S (en) | 1997-01-03 | 1998-08-25 | GGU Gesellschaft fuer Gesundheits-und Umweltforschung mbH | Combined inhaler and cover |
| US5794613A (en) | 1997-01-09 | 1998-08-18 | Sepracor, Inc. | Multiple-dose dispenser for dry powder inhalers |
| USD389238S (en) | 1997-01-24 | 1998-01-13 | Healthscan Products, Inc. | Inhaler mask |
| US6884435B1 (en) | 1997-01-30 | 2005-04-26 | Chiron Corporation | Microparticles with adsorbent surfaces, methods of making same, and uses thereof |
| EP0898978B1 (en) | 1997-01-30 | 2005-03-02 | Unisia Jecs Corporation | Suction type medicator |
| SE9700422D0 (sv) | 1997-02-07 | 1997-02-07 | Astra Ab | Single dose inhaler II |
| SE9700423D0 (sv) | 1997-02-07 | 1997-02-07 | Astra Ab | Disposable inhaler |
| SE9700421D0 (sv) | 1997-02-07 | 1997-02-07 | Astra Ab | Single dose inhaler I |
| JP3011898B2 (ja) | 1997-02-20 | 2000-02-21 | フォルテ グロウ メディカル株式会社 | 吸引器 |
| DE19708406A1 (de) | 1997-03-03 | 1998-09-10 | Alfred Von Schuckmann | Gerät zur dosierten Ausgabe von Substanzen |
| USD390653S (en) | 1997-03-04 | 1998-02-10 | Blasdell Richard J | Inhaler |
| SE9700935D0 (sv) | 1997-03-14 | 1997-03-14 | Astra Ab | Inhalation device |
| SE9700943D0 (sv) | 1997-03-14 | 1997-03-14 | Astra Ab | Powder inhaler V |
| SE9700948D0 (sv) | 1997-03-14 | 1997-03-14 | Astra Ab | Powder inhaler X |
| SE9700936D0 (sv) | 1997-03-14 | 1997-03-14 | Astra Ab | Inhalation device |
| SE9700940D0 (sv) | 1997-03-14 | 1997-03-14 | Astra Ab | Powder inhaler IV |
| SE9700938D0 (sv) | 1997-03-14 | 1997-03-14 | Astra Ab | Powder inhaler II and a method of construction thereof |
| SE9700937D0 (sv) | 1997-03-14 | 1997-03-14 | Astra Ab | Powder inhaler I |
| TW469832U (en) | 1997-03-14 | 2001-12-21 | Astra Ab | Inhalation device |
| US6043214A (en) | 1997-03-20 | 2000-03-28 | Novo Nordisk A/S | Method for producing powder formulation comprising an insulin |
| US6006747A (en) | 1997-03-20 | 1999-12-28 | Dura Pharmaceuticals, Inc. | Dry powder inhaler |
| US5904139A (en) | 1997-03-28 | 1999-05-18 | Hauser; Stephen G. | Breath coordinated inhaler |
| US8391104B2 (en) | 1997-03-28 | 2013-03-05 | Carlos De La Huerga | Interactive medication container labeling |
| US5981488A (en) | 1997-03-31 | 1999-11-09 | Eli Lillly And Company | Glucagon-like peptide-1 analogs |
| CA2284132C (en) | 1997-04-01 | 2004-09-07 | Cima Labs Inc. | Blister package and packaged tablet |
| CN1259045A (zh) | 1997-04-02 | 2000-07-05 | 普渡研究基金会 | 蛋白质的口服释放方法 |
| PT101988B (pt) | 1997-04-04 | 2004-02-27 | Hovione Farmaciencia Sa | Sistema de orientacao e posicionamento de um objecto |
| USD410541S (en) | 1997-06-30 | 1999-06-01 | Novartis Ag | Inhaler |
| SE9702796D0 (sv) | 1997-07-25 | 1997-07-25 | Pharmacia & Upjohn Ab | A device at a pharmaceutical container or inhaler |
| CA2212430A1 (en) | 1997-08-07 | 1999-02-07 | George Volgyesi | Inhalation device |
| GB2327895B (en) | 1997-08-08 | 2001-08-08 | Electrosols Ltd | A dispensing device |
| US5855564A (en) | 1997-08-20 | 1999-01-05 | Aradigm Corporation | Aerosol extrusion mechanism |
| US5846447A (en) | 1997-08-26 | 1998-12-08 | E. I. Du Pont De Nemours And Company | Process for forming a dispersion of polytetrafluoroethylene |
| USD416085S (en) | 1997-09-05 | 1999-11-02 | Pharmacia & Upjohn | Inhaler |
| USD417271S (en) | 1997-09-10 | 1999-11-30 | Medic-Aid Limited | Drug delivery device |
| DE59811840D1 (de) | 1997-09-12 | 2004-09-23 | Pharis Biotec Gmbh | Zusammensetzung zur therapie von diabetes mellitus und fettsucht |
| US5848589A (en) | 1997-09-18 | 1998-12-15 | Welnetz; Robert J. | Altitude mask simulator |
| AU135340S (en) | 1997-09-24 | 1998-10-12 | Innovata Biomed Ltd | An inhaler |
| US6394085B1 (en) | 1997-09-25 | 2002-05-28 | Norton Healthcare Ltd. | Inhaler spacer |
| US6073629A (en) | 1997-09-25 | 2000-06-13 | Norton Healthcare Ltd. | Inhaler spacer |
| USD463544S1 (en) | 1997-09-26 | 2002-09-24 | 1263152 Ontario Inc. | Aerosol medication delivery inhaler |
| US6565885B1 (en) | 1997-09-29 | 2003-05-20 | Inhale Therapeutic Systems, Inc. | Methods of spray drying pharmaceutical compositions |
| AU4894697A (en) | 1997-10-01 | 1999-04-23 | Flemington Pharmaceutical Corporation | Buccal, polar and non-polar spray or capsule |
| US6228394B1 (en) | 1997-10-14 | 2001-05-08 | Boehringer Ingelheim Pharmaceuticals, Inc. | Supercritical fluid extraction of mould lubricant from hard shell capsules |
| US5954047A (en) | 1997-10-17 | 1999-09-21 | Systemic Pulmonary Development, Ltd. | Methods and apparatus for delivering aerosolized medication |
| USD398992S (en) | 1997-10-21 | 1998-09-29 | Schering-Plough Healthcare Products, Inc. | Nasal inhaler |
| ZA989744B (en) | 1997-10-31 | 2000-04-26 | Lilly Co Eli | Method for administering acylated insulin. |
| IN188720B (https=) | 1997-11-06 | 2002-11-02 | Panacea Biotec Ltd | |
| SE9704184D0 (sv) | 1997-11-14 | 1997-11-14 | Astra Ab | Inhalation device |
| AU135120S (en) | 1997-11-14 | 1998-09-21 | Astrazeneca Ab | Inhaler |
| USD412978S (en) | 1997-12-02 | 1999-08-17 | Dura Pharmaceuticals, Inc. | Inhaler |
| US6116238A (en) | 1997-12-02 | 2000-09-12 | Dura Pharmaceuticals, Inc. | Dry powder inhaler |
| USD418600S (en) | 1997-12-04 | 2000-01-04 | Charmaine Haerle | Inhaler clip |
| JP2001525371A (ja) | 1997-12-05 | 2001-12-11 | イーライ・リリー・アンド・カンパニー | Glp−1製剤 |
| US6192876B1 (en) | 1997-12-12 | 2001-02-27 | Astra Aktiebolag | Inhalation apparatus and method |
| US6380357B2 (en) | 1997-12-16 | 2002-04-30 | Eli Lilly And Company | Glucagon-like peptide-1 crystals |
| US5965701A (en) | 1997-12-23 | 1999-10-12 | Ferring Bv | Kappa receptor opioid peptides |
| US6077940A (en) | 1997-12-24 | 2000-06-20 | Genentech, Inc. | Free solution ligand interaction molecular separation method |
| US6358058B1 (en) | 1998-01-30 | 2002-03-19 | 1263152 Ontario Inc. | Aerosol dispensing inhaler training device |
| JP3530004B2 (ja) | 1998-02-06 | 2004-05-24 | 株式会社日立ユニシアオートモティブ | 吸入式投薬器 |
| US6158431A (en) | 1998-02-13 | 2000-12-12 | Tsi Incorporated | Portable systems and methods for delivery of therapeutic material to the pulmonary system |
| USD421800S (en) | 1998-02-19 | 2000-03-21 | Pierre Fabre Medicament | Powder and compressed-air inhaler |
| USD412979S (en) | 1998-02-27 | 1999-08-17 | Diemolding Corporation | Metered dose inhaler spacer |
| US7143764B1 (en) | 1998-03-13 | 2006-12-05 | Astrazeneca Ab | Inhalation device |
| RO121834B1 (ro) | 1998-03-16 | 2008-06-30 | Inhale Therapeutic Systems, Inc. | Dispozitiv pentru administrarea unui agent activ |
| US6998387B1 (en) | 1998-03-19 | 2006-02-14 | Amylin Pharmaceuticals, Inc. | Human appetite control by glucagon-like peptide receptor binding compounds |
| SE9801078D0 (sv) | 1998-03-27 | 1998-03-27 | Shl Medical Ab | Inhalator |
| AU138849S (en) | 1998-03-30 | 1999-11-22 | Astra Ab | Inhaler with cap |
| AU138848S (en) | 1998-03-30 | 1999-11-22 | Astra Ab | Inhaler with cap |
| AU138847S (en) | 1998-03-30 | 1999-11-22 | Astra Ab | Inhaler with cap |
| AU749751B2 (en) | 1998-04-08 | 2002-07-04 | Eli Lilly And Company | Pulmonary and nasal delivery of raloxifene |
| WO1999052506A1 (de) | 1998-04-09 | 1999-10-21 | Axiva Gmbh | Partikulärer wirkstoffträger für die pulmonale applikation |
| FR2777283B1 (fr) | 1998-04-10 | 2000-11-24 | Adir | Nouveaux composes peptidiques analogues du glucagon-peptide- 1 (7-37), leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| US6578571B1 (en) | 1998-04-20 | 2003-06-17 | Infamed Ltd. | Drug delivery device and methods therefor |
| GB9810126D0 (https=) | 1998-05-13 | 1998-07-08 | Glaxo Group Ltd | |
| US6257233B1 (en) | 1998-06-04 | 2001-07-10 | Inhale Therapeutic Systems | Dry powder dispersing apparatus and methods for their use |
| SE9802080D0 (sv) | 1998-06-11 | 1998-06-11 | Hellstroem | Pharmaceutical composition for the treatment of functional dyspepsia and/or irritable bowel syndrome and new use of substances therein |
| US6152130A (en) | 1998-06-12 | 2000-11-28 | Microdose Technologies, Inc. | Inhalation device with acoustic control |
| USD412572S (en) | 1998-06-19 | 1999-08-03 | Gray Gene W | Nasal inhaler adaptor for left and right nostril |
| HU224243B1 (hu) | 1998-06-22 | 2005-06-28 | Astrazeneca Ab, | Készülék port tartalmazó, buborékcsomagolást képező fedőfóliával lezárt mélyedések ürítéséhez, szívás alkalmazásával |
| ATE399565T1 (de) | 1998-07-07 | 2008-07-15 | Transdermal Technologies Inc | Zusammensetzungen für die schnelle und nicht- irritierende transdermale verabreichung von pharmazeutika and verfahren zur formuliering davon und ihren verabreichung |
| DE19831525A1 (de) | 1998-07-14 | 2000-01-20 | Pfeiffer Erich Gmbh & Co Kg | Spender für Medien |
| US6703381B1 (en) | 1998-08-14 | 2004-03-09 | Nobex Corporation | Methods for delivery therapeutic compounds across the blood-brain barrier |
| US6087334A (en) | 1998-08-21 | 2000-07-11 | Amylin Pharmaceuticals, Inc. | Anti-diabetic peptides |
| AU762145C (en) | 1998-08-26 | 2005-03-17 | Teijin Limited | Powdery pernasal compositions |
| WO2000012116A1 (en) | 1998-08-28 | 2000-03-09 | Eli Lilly And Company | Method for administering insulinotropic peptides |
| US6720407B1 (en) | 1998-08-28 | 2004-04-13 | Eli Lilly And Company | Method for administering insulinotropic peptides |
| US20020088458A1 (en) | 1998-09-24 | 2002-07-11 | Astrazeneca Ab | Inhaler |
| IL141816A0 (en) | 1998-09-24 | 2002-03-10 | Astrazeneca Ab | Inhaler |
| GB9820937D0 (en) | 1998-09-26 | 1998-11-18 | Glaxo Group Ltd | Inhalation device |
| GB9820886D0 (en) | 1998-09-26 | 1998-11-18 | Glaxo Group Ltd | Inhalation device |
| US6187291B1 (en) * | 1998-09-28 | 2001-02-13 | Robert Weinstein | Method and device for facilitating combined aerosol and oral treatments for diabetes mellitus |
| USD411005S (en) | 1998-09-29 | 1999-06-15 | Pharmadesign Inc. | Arthritic aid for metered dose inhaler |
| UA73924C2 (en) | 1998-10-09 | 2005-10-17 | Nektar Therapeutics | Device for delivering active agent formulation to lungs of human patient |
| US6279511B1 (en) | 1998-10-23 | 2001-08-28 | Instech Laboratories, Inc. | Powered multichannel infusion and monitoring system |
| US6263871B1 (en) | 1998-10-29 | 2001-07-24 | Richard I. Brown | Mouthpiece with coupler |
| US6235725B1 (en) | 1998-10-30 | 2001-05-22 | Baker Norton Pharmaceuticals, Inc. | Methods and compositions for the prevention of tolerance to medications |
| JP3747134B2 (ja) | 1998-11-04 | 2006-02-22 | キヤノン株式会社 | インクジェット記録ヘッドカートリッジの保管容器 |
| US6261594B1 (en) | 1998-11-25 | 2001-07-17 | The University Of Akron | Chitosan-based nitric oxide donor compositions |
| US6540672B1 (en) | 1998-12-09 | 2003-04-01 | Novo Nordisk A/S | Medical system and a method of controlling the system for use by a patient for medical self treatment |
| GB9827145D0 (en) | 1998-12-09 | 1999-02-03 | Co Ordinated Drug Dev | Improvements in or relating to powders |
| US6375975B1 (en) | 1998-12-21 | 2002-04-23 | Generex Pharmaceuticals Incorporated | Pharmaceutical compositions for buccal and pulmonary application |
| US6552024B1 (en) | 1999-01-21 | 2003-04-22 | Lavipharm Laboratories Inc. | Compositions and methods for mucosal delivery |
| SE9900215D0 (sv) | 1999-01-26 | 1999-01-26 | Pharmacia & Upjohn Ab | New use |
| JP2000217917A (ja) | 1999-01-27 | 2000-08-08 | Unisia Jecs Corp | 吸入式投薬器 |
| US6248363B1 (en) | 1999-11-23 | 2001-06-19 | Lipocine, Inc. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
| IT1309592B1 (it) | 1999-03-05 | 2002-01-24 | Chiesi Farma Spa | Particelle veicolo modificate da utilizzarsi nella preparazione diformulazioni farmaceutiche sotto forma di polimeri per inalazione e |
| ES2286881T3 (es) | 1999-03-05 | 2007-12-01 | Chiesi Farmaceutici S.P.A. | Composiciones farmaceuticas en polvo mejoradas para inhalacion. |
| US6632258B1 (en) | 1999-03-16 | 2003-10-14 | The United States Of America As Represented By The United States Department Of Energy | Coal beneficiation by gas agglomeration |
| US6803044B1 (en) | 1999-03-24 | 2004-10-12 | Zengen, Inc. | Antimicrobial and anti-inflammatory peptides for use in human immunodeficiency virus |
| US6630169B1 (en) | 1999-03-31 | 2003-10-07 | Nektar Therapeutics | Particulate delivery systems and methods of use |
| ES2261195T3 (es) | 1999-04-05 | 2006-11-16 | Mannkind Corporation | Metodo de formacion de particulas finas. |
| USD441859S1 (en) | 1999-04-06 | 2001-05-08 | Istituto Biochimico Pavese Pharma S.P.A. | Disposable dry-powder inhaler |
| BR0010346A (pt) | 1999-05-07 | 2002-02-19 | Imerys Pigments Inc | Método de tratamento de um material particulado de caulim |
| US6417920B1 (en) | 1999-05-11 | 2002-07-09 | Shimadzu Corporation | Particle size analyzer based on laser diffraction method |
| US6514500B1 (en) | 1999-10-15 | 2003-02-04 | Conjuchem, Inc. | Long lasting synthetic glucagon like peptide {GLP-!} |
| GB9911388D0 (en) | 1999-05-18 | 1999-07-14 | Glaxo Group Ltd | Dispenser |
| CA2373239A1 (en) | 1999-05-20 | 2000-11-30 | Pharmasol Gmbh | Stability, biocompatibility optimized adjuvant (sba) for enhancing humoral and cellular immune response |
| US6395300B1 (en) | 1999-05-27 | 2002-05-28 | Acusphere, Inc. | Porous drug matrices and methods of manufacture thereof |
| US7919119B2 (en) | 1999-05-27 | 2011-04-05 | Acusphere, Inc. | Porous drug matrices and methods of manufacture thereof |
| DE69910987T2 (de) | 1999-06-14 | 2004-05-19 | Baxter International Inc., Deerfield | Mikrosphären mit verzögerter Wirkstoffabgabe |
| SE516826C2 (sv) | 1999-06-18 | 2002-03-05 | Shl Medical Ab | Anordning i en inhalator med organ för aktivering och avaktivering av en kanister som svar på ett luftflöde |
| US6644315B2 (en) | 1999-06-18 | 2003-11-11 | Saeed Ziaee | Nasal mask |
| US7169889B1 (en) | 1999-06-19 | 2007-01-30 | Biocon Limited | Insulin prodrugs hydrolyzable in vivo to yield peglylated insulin |
| USRE40876E1 (en) | 1999-06-21 | 2009-08-18 | Eli Lilly And Company | Method for treating non-insulin dependent diabetes using thiazolidinediones with glucagonlike peptide-1 and agonists thereof |
| US6858199B1 (en) | 2000-06-09 | 2005-02-22 | Advanced Inhalation Research, Inc. | High efficient delivery of a large therapeutic mass aerosol |
| GB2353222B (en) | 1999-06-23 | 2001-09-19 | Cambridge Consultants | Inhalers |
| USD444226S1 (en) | 1999-06-24 | 2001-06-26 | Novo Nordisk A/S | Inhaler |
| ES2569916T3 (es) | 1999-06-29 | 2016-05-13 | Mannkind Corporation | Formulaciones farmacéuticas que comprenden insulina complejada con una dicetopiperazina |
| US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
| US6606992B1 (en) | 1999-06-30 | 2003-08-19 | Nektar Therapeutics | Systems and methods for aerosolizing pharmaceutical formulations |
| ITMI991582A1 (it) | 1999-07-16 | 2001-01-16 | Chiesi Farma Spa | Polveri costituite da particelle aventi la superficie perfettamente levigata da utilizzare come veicoli per la preparazione di miscele inala |
| US7305986B1 (en) | 1999-07-23 | 2007-12-11 | Mannkind Corporation | Unit dose capsules for use in a dry powder inhaler |
| ATE390944T1 (de) | 1999-07-23 | 2008-04-15 | Mannkind Corp | Einzelportionskapseln für einen trockenpulverinhalator |
| US7464706B2 (en) | 1999-07-23 | 2008-12-16 | Mannkind Corporation | Unit dose cartridge and dry powder inhaler |
| US20010036481A1 (en) | 1999-08-25 | 2001-11-01 | Advanced Inhalation Research, Inc. | Modulation of release from dry powder formulations |
| CN1175961C (zh) | 1999-09-17 | 2004-11-17 | 株式会社新王磁材 | 稀土合金的切割方法和切割装置 |
| USD438612S1 (en) | 1999-09-27 | 2001-03-06 | G-Intek Co., Ltd. | Snivel inhaler |
| PT1220700E (pt) | 1999-10-06 | 2003-08-29 | Angela Eckardt | Aparelho de inalacao para po seco controlado pela respiracao |
| DE60025019T2 (de) | 1999-10-29 | 2006-08-24 | Nektar Therapeutics, San Carlos | Trockenpulverzusammensetzungen mit verbesserter dispersivität |
| SE9903990D0 (sv) | 1999-11-02 | 1999-11-02 | Shl Medical Ab | Inhalator with aerosolizing unit |
| GB9928311D0 (en) | 1999-11-30 | 2000-01-26 | Novartis Ag | Organic compounds |
| IT1308581B1 (it) | 1999-12-03 | 2002-01-08 | Medel Italiana Srl | Apparato per nebulizzare un liquido, in particolare per uso medico. |
| SE9904706D0 (sv) | 1999-12-21 | 1999-12-21 | Astra Ab | An inhalation device |
| PE20010720A1 (es) | 1999-12-11 | 2001-07-26 | Glaxo Group Ltd | Distribuidor de medicamento |
| US7204250B1 (en) | 1999-12-16 | 2007-04-17 | Compumedics Limited | Bio-mask |
| US7022674B2 (en) | 1999-12-16 | 2006-04-04 | Eli Lilly And Company | Polypeptide compositions with improved stability |
| DE19961300A1 (de) | 1999-12-18 | 2001-06-21 | Asta Medica Ag | Vorratssystem für Arzneimittel in Pulverform und damit ausgestatteter Inhalator |
| EP1242112A4 (en) | 1999-12-21 | 2005-02-09 | Rxkinetix Inc | PRODUCTS CONTAINING MEDICINANT SUBSTANCE PARTICLES AND PROCESS FOR PREPARING THE SAME |
| US7080642B2 (en) | 1999-12-22 | 2006-07-25 | 3M Innovative Properties Company | Refillable device with counting means |
| NZ520379A (en) | 1999-12-30 | 2004-05-28 | Chiron Corp | Methods for administrering interleukin-2 by pulmonary inhalation |
| WO2001051071A2 (en) | 2000-01-11 | 2001-07-19 | Novo Nordisk A/S | Transepithelial delivery of glp-1 derivatives |
| DK1248594T3 (da) | 2000-01-19 | 2006-02-06 | Mannkind Corp | Formulering med multi-spidsfrigivelse til indgivelse af lægemidler |
| WO2001052818A1 (en) | 2000-01-19 | 2001-07-26 | Pharmaceutical Discovery Corporation | Dry powder formulations of antihistamine for nasal administration |
| US6540982B1 (en) | 2000-01-25 | 2003-04-01 | Aeropharm Technology Incorporated | Medical aerosol formulation |
| US6443307B1 (en) | 2000-01-25 | 2002-09-03 | Michael D. Burridge | Medication dispenser with an internal ejector |
| US6540983B1 (en) | 2000-01-25 | 2003-04-01 | Aeropharm Technology Incorporated | Medical aerosol formulation |
| TR200401142T4 (tr) | 2000-01-27 | 2004-07-21 | Eli Lilly And Company | Glükagon-benzeri peptid bileşiklerinin çözündürülmesi için işlem. |
| US6427688B1 (en) | 2000-02-01 | 2002-08-06 | Dura Pharmaceuticals, Icn. | Dry powder inhaler |
| US7171965B2 (en) | 2000-02-01 | 2007-02-06 | Valois S.A.S. | Breath actuated dry powder inhaler and tape dose strip |
| USD439325S1 (en) | 2000-02-08 | 2001-03-20 | Baker Norton Pharmaceuticals, Inc. | Cover for a nasal inhaler |
| EP1129705A1 (en) | 2000-02-17 | 2001-09-05 | Rijksuniversiteit te Groningen | Powder formulation for inhalation |
| GB0004456D0 (en) | 2000-02-26 | 2000-04-19 | Glaxo Group Ltd | Medicament dispenser |
| US7089934B2 (en) | 2000-02-28 | 2006-08-15 | Vectura Limited | Delivery of oral drugs |
| USD439656S1 (en) | 2000-03-06 | 2001-03-27 | Astrazeneca Uk Limited | Inhaler |
| US6443151B1 (en) | 2000-03-08 | 2002-09-03 | Aradigm Corporation | Fluid velocity-sensitive trigger mechanism |
| AU3110201A (en) | 2000-03-10 | 2001-09-24 | Univ North Carolina | Dry powder inhaler devices, multi-dose dry powder drug packages, control systems, and associated methods |
| US6608038B2 (en) | 2000-03-15 | 2003-08-19 | Novartis Ag | Methods and compositions for treatment of diabetes and related conditions via gene therapy |
| GB2360216A (en) | 2000-03-18 | 2001-09-19 | Astrazeneca Uk Ltd | Inhaler |
| GB2360218A (en) | 2000-03-18 | 2001-09-19 | Astrazeneca Uk Ltd | Inhaler |
| GB0006525D0 (en) | 2000-03-18 | 2000-05-10 | Astrazeneca Uk Ltd | Inhaler |
| US6823863B2 (en) | 2000-03-18 | 2004-11-30 | Astrazeneca Ab | Inhaler |
| SE0000935D0 (sv) | 2000-03-21 | 2000-03-21 | Astrazeneca Ab | An inhalation device |
| USD449684S1 (en) | 2000-03-24 | 2001-10-23 | Astrazeneca Ab | Inhaler |
| US6432383B1 (en) | 2000-03-30 | 2002-08-13 | Generex Pharmaceuticals Incorporated | Method for administering insulin |
| WO2001074247A2 (en) | 2000-04-03 | 2001-10-11 | Iep Pharmaceutical Devices Inc. | Method for measuring changes in the airways of humans and other mammals |
| CA2733850C (en) | 2000-04-11 | 2013-10-22 | Trudell Medical International | Aerosol delivery apparatus with positive expiratory pressure capacity |
| DE10019879A1 (de) | 2000-04-20 | 2001-10-25 | Degussa | Verfahren zur Herstellung von 2,5-Diketopiperazinen, neue 2,5-Diketopiperazine und deren Verwendung |
| MY136453A (en) | 2000-04-27 | 2008-10-31 | Philip Morris Usa Inc | "improved method and apparatus for generating an aerosol" |
| US6447750B1 (en) | 2000-05-01 | 2002-09-10 | Aeropharm Technology Incorporated | Medicinal aerosol formulation |
| US6468507B1 (en) | 2000-05-01 | 2002-10-22 | Aeropharm Technology, Inc. | Non-aqueous aerosol formulation comprising rosiglitazone maleate, a non-aqueous carrier, and an amino acid stabilizer |
| USD442685S1 (en) | 2000-05-02 | 2001-05-22 | Salter Labs | Medication inhaler spacer |
| US20010039442A1 (en) | 2000-05-06 | 2001-11-08 | Sal Gorge | Headache relief device |
| US6948494B1 (en) | 2000-05-10 | 2005-09-27 | Innovative Devices, Llc. | Medicament container with same side airflow inlet and outlet and method of use |
| US7512069B2 (en) | 2000-05-18 | 2009-03-31 | Exfo Service Assurance, Inc. | IP packet identification method and system for TCP connection and UDP stream |
| US20020000225A1 (en) | 2000-06-02 | 2002-01-03 | Carlos Schuler | Lockout mechanism for aerosol drug delivery devices |
| CN1141974C (zh) | 2000-06-07 | 2004-03-17 | 张昊 | 结肠定位释放的口服生物制剂 |
| ATE424413T1 (de) | 2000-06-16 | 2009-03-15 | Lilly Co Eli | Analoge des glucagon-ähnlichen peptids-1 |
| RU2181297C2 (ru) | 2000-06-20 | 2002-04-20 | Эпштейн Олег Ильич | Способ лечения патологического синдрома и лекарственное средство |
| GB0015043D0 (en) | 2000-06-21 | 2000-08-09 | Glaxo Group Ltd | Medicament dispenser |
| GB0015034D0 (en) | 2000-06-21 | 2000-08-09 | Glaxo Group Ltd | Inhalation device |
| AR028747A1 (es) | 2000-06-23 | 2003-05-21 | Norton Health Care Ltd | Desaglomerador para inhalador de polvo seco accionado por la respiracion, un inhalador de polvo seco y un metodo de desaglomeracion de polvo seco. |
| AR028746A1 (es) | 2000-06-23 | 2003-05-21 | Norton Health Care Ltd | Cartucho de dosis previamente medidas para inhalador de polvo seco accionado por la respiracion, el inhalador y un metodo de provision de dosis previamente medidas de polvo seco |
| PE20020163A1 (es) | 2000-06-23 | 2002-03-04 | Norton Healthcare Ltd | Sistema presurizado de receptaculo para inhalador de medicamento |
| US6562807B2 (en) | 2000-06-23 | 2003-05-13 | Novo Nordisk A/S | Glucagon antagonists/inverse agonists |
| USD450117S1 (en) | 2000-06-29 | 2001-11-06 | Innovata Biomed Limited | Inhaler |
| USD452910S1 (en) | 2000-06-29 | 2002-01-08 | Innovata Biomend Limited | Inhaler |
| WO2002002560A2 (en) | 2000-07-04 | 2002-01-10 | Novo Nordisk A/S | Purine-2,6-diones which are inhibitors of the enzyme dipeptidyl peptidase iv (dpp-iv) |
| US6363932B1 (en) | 2000-07-06 | 2002-04-02 | Clinical Technologies, Inc. | Aerosol enhancement device |
| US6951215B1 (en) | 2000-07-14 | 2005-10-04 | Tufts University | Drug delivery device for animals |
| US6360929B1 (en) | 2000-07-17 | 2002-03-26 | Mccarthy Madeleine | Medicinal atomizing inhaler pouch/retainer |
| GB2364919A (en) | 2000-07-21 | 2002-02-13 | Cambridge Consultants | Inhalers |
| WO2002011676A2 (en) | 2000-08-04 | 2002-02-14 | Dmi Biosciences, Inc. | Method of using diketopiperazines and composition containing them |
| AU2001284697A1 (en) | 2000-08-04 | 2002-02-18 | Dmi Biosciences, Inc. | Method of synthesizing diketopiperazines |
| WO2002012266A1 (en) | 2000-08-05 | 2002-02-14 | Glaxo Group Limited | 17.beta.-carbothioate 17.alpha.-arylcarbonyloxyloxy androstane derivative as anti-inflammatory agents |
| TWI283182B (en) | 2000-08-07 | 2007-07-01 | Nektar Therapeutics | Inhalable spray dried 4-helix bundle protein powders having minimized aggregation |
| WO2002013897A2 (en) | 2000-08-14 | 2002-02-21 | Advanced Inhalation Research, Inc. | Inhalation device and method |
| US6704255B2 (en) | 2000-08-22 | 2004-03-09 | Ricoh Company, Ltd. | Lens actuator |
| US6613308B2 (en) | 2000-09-19 | 2003-09-02 | Advanced Inhalation Research, Inc. | Pulmonary delivery in treating disorders of the central nervous system |
| US6514482B1 (en) | 2000-09-19 | 2003-02-04 | Advanced Inhalation Research, Inc. | Pulmonary delivery in treating disorders of the central nervous system |
| USD460173S1 (en) | 2000-09-20 | 2002-07-09 | P.A. Knowledge Limited | Inhaler device |
| CN1299779C (zh) | 2000-09-20 | 2007-02-14 | 弗朗哥·德伯恩 | 用于吸入设备的喷雾装置及带有喷雾装置的吸入设备 |
| SE517225C2 (sv) | 2000-09-21 | 2002-05-14 | Microdrug Ag | Optimering av en elektrostatiskt doserad inhalator för torrt pulver |
| SE517226C2 (sv) | 2000-09-25 | 2002-05-14 | Microdrug Ag | Inhalator med luftbroms för torrt pulver |
| SE517228C2 (sv) | 2000-09-25 | 2002-05-14 | Microdrug Ag | Inhalator för torrt pulver med andningsaktivering |
| GB0023653D0 (en) | 2000-09-27 | 2000-11-08 | Cambridge Consultants | Device for dispensing particulate material |
| DE60119139T2 (de) | 2000-09-29 | 2007-06-14 | Pfizer Ltd., Sandwich | Druckempfindliche vorrichtung und herstellungsverfahren |
| US6756062B2 (en) | 2000-11-03 | 2004-06-29 | Board Of Regents University Of Texas System | Preparation of drug particles using evaporation precipitation into aqueous solutions |
| WO2002043703A1 (fr) | 2000-11-29 | 2002-06-06 | Itoham Foods Inc. | Preparations pulverulentes et son procede de production |
| GB0029562D0 (en) | 2000-12-04 | 2001-01-17 | Novartis Ag | Organic compounds |
| USD455208S1 (en) | 2000-12-05 | 2002-04-02 | Clinical Designs Limited | Inhaler |
| US7259233B2 (en) | 2000-12-13 | 2007-08-21 | Eli Lilly And Company | Chronic treatment regimen using glucagon-like insulinotropic peptides |
| DE60127175T2 (de) | 2000-12-21 | 2007-11-08 | Nektar Therapeutics, San Carlos | Lagerstabile pulverzusammensetzungen mit interleukin-4 rezeptor |
| US6799572B2 (en) | 2000-12-22 | 2004-10-05 | Chrysalis Technologies Incorporated | Disposable aerosol generator system and methods for administering the aerosol |
| US7077130B2 (en) | 2000-12-22 | 2006-07-18 | Chrysalis Technologies Incorporated | Disposable inhaler system |
| WO2002053190A2 (en) | 2000-12-29 | 2002-07-11 | Advanced Inhalation Research, Inc. | Particles for inhalation having sustained release properties |
| US20020141946A1 (en) | 2000-12-29 | 2002-10-03 | Advanced Inhalation Research, Inc. | Particles for inhalation having rapid release properties |
| US6626173B2 (en) | 2001-01-08 | 2003-09-30 | Iep Pharmaceutical Devices Inc. | Dry powder inhaler |
| US6644309B2 (en) | 2001-01-12 | 2003-11-11 | Becton, Dickinson And Company | Medicament respiratory delivery device and method |
| FI20010144A0 (fi) | 2001-01-24 | 2001-01-24 | Valtion Teknillinen | Menetelmä ja laite aerosolilähteiden tutkimiseksi |
| AUPR272901A0 (en) | 2001-01-25 | 2001-02-22 | Gainful Plan Limited | Method of preparing biological materials and preparations produced using same |
| US6652886B2 (en) * | 2001-02-16 | 2003-11-25 | Expression Genetics | Biodegradable cationic copolymers of poly (alkylenimine) and poly (ethylene glycol) for the delivery of bioactive agents |
| GB2374010B (en) | 2001-02-26 | 2004-12-29 | Council Scient Ind Res | Novel vitamin B12 - biodegradable micro particulate conjugate carrier systems for peroral delivery of drugs, therapeutic peptides/proteins and vaccines |
| ATE255929T1 (de) | 2001-03-05 | 2003-12-15 | Ivo Pera | Inhalationsvorrichtung zum dispergieren von in kapseln enthaltenen pulverförmigen medikamente durch den respirationstrakt |
| US6698422B2 (en) | 2001-03-12 | 2004-03-02 | Birdsong Medical Devices, Inc. | Canister inhaler having a spacer and easy to operate lever mechanism and a flexible, elastic mouthpiece |
| US6523536B2 (en) | 2001-03-12 | 2003-02-25 | Birdsong Medical Devices, Inc. | Dual-canister inhaler having a spacer and easy to operate lever mechanism |
| USD453264S1 (en) | 2001-03-30 | 2002-02-05 | Benjamin Acevedo, Jr. | Pouch for medical inhaler |
| GB0108213D0 (en) | 2001-04-02 | 2001-05-23 | Glaxo Group Ltd | Medicament dispenser |
| US6652838B2 (en) | 2001-04-05 | 2003-11-25 | Robert E. Weinstein | Method for treating diabetes mellitus |
| SE518397C2 (sv) | 2001-04-05 | 2002-10-01 | Microdrug Ag | Förfarande och anordning för frigörande av pulver och inhalatoranordning för administrering av medicinskt pulver |
| WO2002083066A2 (en) | 2001-04-11 | 2002-10-24 | Bristol-Myers Squibb Company | Amino acid complexes of c-aryl glucosides for treatment of diabetes and method |
| US6766799B2 (en) | 2001-04-16 | 2004-07-27 | Advanced Inhalation Research, Inc. | Inhalation device |
| US6447751B1 (en) | 2001-04-18 | 2002-09-10 | Robert E. Weinstein | Method and device for facilitating combined aerosol and oral treatments for diabetes mellitus |
| CA2504976C (en) | 2001-04-19 | 2011-10-11 | Technology Innovation Limited | Medicament container |
| USD451597S1 (en) | 2001-04-24 | 2001-12-04 | G-Intek Co.,Ltd | Snivel inhaler |
| US7232897B2 (en) | 2001-04-24 | 2007-06-19 | Harvard University, President And Fellows Of Harvard College | Compositions and methods for modulating NH2-terminal Jun Kinase activity |
| JP4663906B2 (ja) | 2001-04-26 | 2011-04-06 | 富士フイルム株式会社 | セルロースアシレートフイルム |
| GB2375308A (en) | 2001-05-10 | 2002-11-13 | Cambridge Consultants | Inhalers |
| CA2444729A1 (en) | 2001-05-10 | 2002-11-14 | Vectura Delivery Devices Limited | Inhalers |
| JP2004535401A (ja) | 2001-05-21 | 2004-11-25 | ネクター セラピューティックス | 化学的に改変されたインスリンの肺投与 |
| SE0101825D0 (sv) | 2001-05-22 | 2001-05-22 | Astrazeneca Ab | An Inhalation device |
| US7144863B2 (en) | 2001-06-01 | 2006-12-05 | Eli Lilly And Company | GLP-1 formulations with protracted time action |
| US7035294B2 (en) | 2001-06-04 | 2006-04-25 | Calix Networks, Inc. | Backplane bus |
| EG24184A (en) | 2001-06-15 | 2008-10-08 | Otsuka Pharma Co Ltd | Dry powder inhalation system for transpulmonary |
| FI20011317A0 (fi) | 2001-06-20 | 2001-06-20 | Orion Corp | Jauheinhalaattori |
| US6681768B2 (en) | 2001-06-22 | 2004-01-27 | Sofotec Gmbh & Co. Kg | Powder formulation disintegrating system and method for dry powder inhalers |
| ATE301594T1 (de) | 2001-06-22 | 2005-08-15 | 3M Innovative Properties Co | Verfahren zur verbesserung des durchflusses einer aerosolformulierung in einem dosierventil für einen dosierinhalator |
| DE10136555A1 (de) | 2001-07-27 | 2003-02-13 | Boehringer Ingelheim Int | Optimierte Verfahren zur Bestimmung der Aerosol-Partikelgrößenverteilung und Vorrichtung zur Durchführung derartiger Verfahren |
| US7414720B2 (en) | 2001-07-27 | 2008-08-19 | Herbert Wachtel | Measuring particle size distribution in pharmaceutical aerosols |
| GB0120018D0 (en) | 2001-08-16 | 2001-10-10 | Meridica Ltd | Pack containing medicament and dispensing device |
| PL366855A1 (en) | 2001-08-22 | 2005-02-07 | Aventis Pharma Deutschland Gmbh | Combination preparations of aryl substituted propanolamine derivatives with other active ingredients and the use thereof |
| CA2458371A1 (en) | 2001-08-23 | 2003-03-06 | Eli Lilly And Company | Glucagon-like peptide-1 analogs |
| CA2452044A1 (en) | 2001-08-28 | 2003-03-13 | Eli Lilly And Company | Pre-mixes of glp-1 and basal insulin |
| GB0121709D0 (en) | 2001-09-07 | 2001-10-31 | Imp College Innovations Ltd | Food inhibition agent |
| WO2003024396A2 (en) | 2001-09-17 | 2003-03-27 | Glaxo Group Limited | Dry powder medicament formulations |
| CN1313171C (zh) | 2001-09-19 | 2007-05-02 | 埃德文特药物有限公司 | 吸入器 |
| US6640050B2 (en) | 2001-09-21 | 2003-10-28 | Chrysalis Technologies Incorporated | Fluid vaporizing device having controlled temperature profile heater/capillary tube |
| US6568390B2 (en) | 2001-09-21 | 2003-05-27 | Chrysalis Technologies Incorporated | Dual capillary fluid vaporizing device |
| JP4795637B2 (ja) | 2001-09-28 | 2011-10-19 | カーブ テクノロジー,インコーポレイティド | 鼻ネブライザー |
| WO2003030974A1 (en) | 2001-10-08 | 2003-04-17 | Eli Lilly And Company | Portable medication inhalation kit |
| NZ532694A (en) | 2001-10-16 | 2005-03-24 | Internat Non Toxic Composites | High density non-toxic composites comprising tungsten, another metal and polymer powder |
| USD461239S1 (en) | 2001-10-18 | 2002-08-06 | Anna L. Cassidy | Inhaler sleeve with spring clip |
| WO2003035099A1 (en) | 2001-10-19 | 2003-05-01 | Eli Lilly And Company | Biphasic mixtures of glp-1 and insulin |
| JP2005508220A (ja) | 2001-10-24 | 2005-03-31 | パーリ・ゲーエムベーハー | 薬用組成物調製用具 |
| USD473298S1 (en) | 2001-11-01 | 2003-04-15 | Astrazeneca Ab | Inhaler refill |
| US8637305B2 (en) | 2001-11-07 | 2014-01-28 | Mannkind Corporation | Expression vectors encoding epitopes of target-associated antigens and methods for their design |
| JP2005514393A (ja) | 2001-12-19 | 2005-05-19 | ネクター セラピューティクス | アミノグリコシドの肺への供給 |
| US6994083B2 (en) | 2001-12-21 | 2006-02-07 | Trudell Medical International | Nebulizer apparatus and method |
| GB0130857D0 (en) | 2001-12-22 | 2002-02-06 | Glaxo Group Ltd | Medicament dispenser |
| USD471273S1 (en) | 2002-01-07 | 2003-03-04 | Aerogen, Inc. | Inhaler for dispensing medication |
| US20030198666A1 (en) | 2002-01-07 | 2003-10-23 | Richat Abbas | Oral insulin therapy |
| USD469866S1 (en) | 2002-01-07 | 2003-02-04 | Aerogen, Inc. | Inhaler for dispensing medication |
| USD474536S1 (en) | 2002-01-07 | 2003-05-13 | Aerogen, Inc. | Inhaler for dispensing medications |
| USD479745S1 (en) | 2002-01-07 | 2003-09-16 | Aerogen, Inc. | Inhaler for dispensing medications |
| ITMI20020078A1 (it) | 2002-01-16 | 2003-07-16 | Fabrizio Niccolai | Dispositivo utilizzabile nel tratamento di affezzioni delle vie respiratorie |
| WO2003061578A2 (en) | 2002-01-18 | 2003-07-31 | Mannkind Corporation | Compositions for treatment or prevention of bioterrorism |
| US7258118B2 (en) | 2002-01-24 | 2007-08-21 | Sofotec Gmbh & Co, Kg | Pharmaceutical powder cartridge, and inhaler equipped with same |
| CN1332711C (zh) | 2002-02-20 | 2007-08-22 | 埃米球科技有限公司 | 施用glp-1分子的方法 |
| US6591832B1 (en) | 2002-02-21 | 2003-07-15 | Saint-Gobain Calmar Inc. | Dry powder dispenser |
| US6923175B2 (en) | 2002-03-20 | 2005-08-02 | Mannkind Corporation | Inhalation apparatus |
| US7008644B2 (en) | 2002-03-20 | 2006-03-07 | Advanced Inhalation Research, Inc. | Method and apparatus for producing dry particles |
| UA80123C2 (en) | 2002-04-09 | 2007-08-27 | Boehringer Ingelheim Pharma | Inhalation kit comprising inhalable powder of tiotropium |
| US20030235538A1 (en) | 2002-04-09 | 2003-12-25 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Method for the administration of an anticholinergic by inhalation |
| US20030194420A1 (en) | 2002-04-11 | 2003-10-16 | Richard Holl | Process for loading a drug delivery device |
| USD475133S1 (en) | 2002-04-18 | 2003-05-27 | Mcluckie Lynne E. | Luminescent-colored inhaler |
| US7316748B2 (en) | 2002-04-24 | 2008-01-08 | Wisconsin Alumni Research Foundation | Apparatus and method of dispensing small-scale powders |
| US6830046B2 (en) | 2002-04-29 | 2004-12-14 | Hewlett-Packard Development Company, L.P. | Metered dose inhaler |
| USD478983S1 (en) | 2002-05-01 | 2003-08-26 | Chrysalis Technologies Incorporated | Inhaler |
| US20040151059A1 (en) | 2002-05-01 | 2004-08-05 | Roberts Ii William Leroy | Deagglomerator apparatus and method |
| EP1506003A1 (en) | 2002-05-07 | 2005-02-16 | Novo Nordisk A/S | Soluble formulations comprising insulin aspart and insulin detemir |
| US6889690B2 (en) | 2002-05-10 | 2005-05-10 | Oriel Therapeutics, Inc. | Dry powder inhalers, related blister devices, and associated methods of dispensing dry powder substances and fabricating blister packages |
| USD473640S1 (en) | 2002-05-13 | 2003-04-22 | Iep Pharmaceutical Devices Inc. | Breath actuated inhaler |
| USD492769S1 (en) | 2002-05-24 | 2004-07-06 | Glaxosmithkline K.K. | Lens for an inhaler |
| USD477665S1 (en) | 2002-06-12 | 2003-07-22 | Microdrug Ag | Inhaler |
| AU154760S (en) | 2002-06-20 | 2004-03-02 | Astrazeneca Ab | Inhaler |
| WO2004002551A2 (en) | 2002-06-28 | 2004-01-08 | Advanced Inhalation Research, Inc. | Inhalable epinephrine |
| US20060003316A1 (en) | 2002-07-15 | 2006-01-05 | John Simard | Immunogenic compositions derived from poxviruses and methods of using same |
| GB0217198D0 (en) | 2002-07-25 | 2002-09-04 | Glaxo Group Ltd | Medicament dispenser |
| GB0217382D0 (en) | 2002-07-26 | 2002-09-04 | Pfizer Ltd | Process for making orally consumable dosage forms |
| USD489448S1 (en) | 2002-07-31 | 2004-05-04 | Advanced Inhalations Revolutions, Inc. | Vaporization apparatus |
| EP1658872B2 (en) | 2002-07-31 | 2019-08-21 | CHIESI FARMACEUTICI S.p.A. | Powder inhaler |
| JP4828940B2 (ja) | 2002-08-01 | 2011-11-30 | マンカインド コーポレイション | 細胞輸送組成物およびこれらの使用 |
| DE10235168A1 (de) | 2002-08-01 | 2004-02-12 | Aventis Pharma Deutschland Gmbh | Verfahren zur Reinigung von Preproinsulin |
| US20040038865A1 (en) | 2002-08-01 | 2004-02-26 | Mannkind Corporation | Cell transport compositions and uses thereof |
| US20150283213A1 (en) | 2002-08-01 | 2015-10-08 | Mannkind Corporation | Method for treating hyperglycemia with glp-1 |
| US20080260838A1 (en) | 2003-08-01 | 2008-10-23 | Mannkind Corporation | Glucagon-like peptide 1 (glp-1) pharmaceutical formulations |
| WO2004020408A1 (en) * | 2002-08-29 | 2004-03-11 | Merck & Co., Inc. | Indoles having anti-diabetic activity |
| GB0315791D0 (en) | 2003-07-07 | 2003-08-13 | 3M Innovative Properties Co | Two component molded valve stems |
| US7404796B2 (en) * | 2004-03-01 | 2008-07-29 | Becton Dickinson And Company | System for determining insulin dose using carbohydrate to insulin ratio and insulin sensitivity factor |
| US20040121964A1 (en) | 2002-09-19 | 2004-06-24 | Madar David J. | Pharmaceutical compositions as inhibitors of dipeptidyl peptidase-IV (DPP-IV) |
| USD509296S1 (en) | 2002-09-21 | 2005-09-06 | Aventis Pharma Limited | Inhaler |
| JP2004121061A (ja) | 2002-10-01 | 2004-04-22 | Sanei Gen Ffi Inc | 粉末組成物の製造方法 |
| AU2003272935C1 (en) | 2002-10-11 | 2009-06-25 | Otsuka Pharmaceutical Co., Ltd. | Powder inhalation device |
| CN1176649C (zh) | 2002-10-16 | 2004-11-24 | 上海医药工业研究院 | 舒马普坦干粉吸入剂及其制备方法 |
| ITMO20020297A1 (it) | 2002-10-16 | 2004-04-17 | Roberto Oliva | Inalatore per preparati monodose in capsule. |
| NZ540318A (en) | 2002-10-31 | 2007-09-28 | Umd Inc | Therapeutic compositions for drug delivery to and through covering epithelia |
| WO2004041338A1 (en) | 2002-11-04 | 2004-05-21 | Cambridge Consultants Limited | Inhalers |
| USD493220S1 (en) | 2002-11-06 | 2004-07-20 | Merck Patent Gmbh | Inhaler |
| US20080015457A1 (en) | 2002-11-07 | 2008-01-17 | Silva Carlos D | Device for Monitoring Respiratory Movements |
| USD483860S1 (en) | 2002-11-12 | 2003-12-16 | Pari Gmbh Spezialisten Fur Effektive Inhalation | Electronic inhaler and control unit |
| US6904907B2 (en) | 2002-11-19 | 2005-06-14 | Honeywell International Inc. | Indirect flow measurement through a breath-operated inhaler |
| US7913688B2 (en) | 2002-11-27 | 2011-03-29 | Alexza Pharmaceuticals, Inc. | Inhalation device for producing a drug aerosol |
| US20040138099A1 (en) * | 2002-11-29 | 2004-07-15 | Draeger Eberhard Kurt | Insulin administration regimens for the treatment of subjects with diabetes |
| MXPA05005864A (es) | 2002-12-02 | 2005-11-16 | Univ Alberta | Dispositivo y metodo para desaglomeracion de polvo para inhalacion. |
| US7284553B2 (en) | 2002-12-12 | 2007-10-23 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Powder inhaler comprising a chamber for a capsule for taking up a non-returnable capsule being filled with an active ingredient |
| EA007730B1 (ru) | 2002-12-13 | 2006-12-29 | Оцука Фармасьютикал Ко., Лтд. | Ингаляционное устройство для транспульмонального введения |
| AR042453A1 (es) | 2002-12-13 | 2005-06-22 | Otsuka Pharma Co Ltd | Una composicion de interferon-gamma liofilizada para administracion transpulmonar y un sistema para su inhalacion |
| EA008829B1 (ru) | 2002-12-17 | 2007-08-31 | Нэстек Фармасьютикал Кампани Инк. | Композиции и способы для усовершенствованной доставки пептидов, связывающихся с y-рецепторами, которую осуществляют через слизистые оболочки, и способы лечения и предотвращения ожирения |
| US6941947B2 (en) | 2002-12-18 | 2005-09-13 | Quadrant Technologies Limited | Unit dose dry powder inhaler |
| US7185650B2 (en) | 2002-12-19 | 2007-03-06 | Arie Huber | Systems and methods for determining a minimum effective dose of an inhaled drug for an individual patient at a given time |
| US6962006B2 (en) | 2002-12-19 | 2005-11-08 | Acusphere, Inc. | Methods and apparatus for making particles using spray dryer and in-line jet mill |
| CA2509755A1 (en) * | 2002-12-27 | 2004-07-22 | Diobex, Inc. | Compositions and methods for the prevention and control of insulin-induced hypoglycemia |
| DE10300032B3 (de) | 2003-01-03 | 2004-05-27 | E. Braun Gmbh | Pulverinhalator |
| GB0309154D0 (en) | 2003-01-14 | 2003-05-28 | Aventis Pharma Inc | Use of insulin glargine to reduce or prevent cardiovascular events in patients being treated for dysglycemia |
| WO2004064705A2 (en) | 2003-01-17 | 2004-08-05 | Schering Corporation | Training device for medicament inhalers |
| EP1605916A4 (en) | 2003-02-12 | 2012-02-22 | R & P Korea Co Ltd | SOLVENT SYSTEM OF A SMOOTH MEDICAMENT WITH IMPROVED ELUTION RATE |
| GB0303870D0 (en) | 2003-02-20 | 2003-03-26 | Norton Healthcare Ltd | Pre-metered dose magazine for breath-actuated dry powder inhaler |
| US20040171518A1 (en) | 2003-02-27 | 2004-09-02 | Medtronic Minimed, Inc. | Compounds for protein stabilization and methods for their use |
| WO2004078236A2 (en) | 2003-03-04 | 2004-09-16 | Norton Healthcare Limited | Medicament dispensing device with a display indicative of the state of an internal medicament reservoir |
| EA200501422A1 (ru) | 2003-03-04 | 2006-04-28 | Дзе Текнолоджи Девелопмент Компани Лтд. | Длительнодействующая инъецируемая композиция инсулина и способы её изготовления и применения |
| WO2004080401A2 (en) | 2003-03-06 | 2004-09-23 | Emisphere Technologies, Inc. | Oral insulin therapies and protocol |
| WO2004080482A2 (en) | 2003-03-11 | 2004-09-23 | Institut De Cardiologie De Montréal / | Use of angiotensin converting enzyme (ace) inhibitors to prevent diabetes in a subject with chronic heart failure |
| USD499802S1 (en) | 2003-04-01 | 2004-12-14 | Chiesi Farmaceutici S.P.A. | Powder inhaler |
| HUE026950T2 (en) | 2003-04-09 | 2016-08-29 | Novartis Ag | Nozzle with guide wire for puncturing the capsule |
| US20040204439A1 (en) | 2003-04-14 | 2004-10-14 | Staniforth John Nicholas | Composition, device, and method for treating sexual dysfunction via inhalation |
| EP1468935A1 (de) | 2003-04-16 | 2004-10-20 | Alcan Technology & Management Ltd. | Blisterverpackung |
| AU155845S (en) | 2003-05-15 | 2004-07-13 | Glaxo Group Ltd | A dispensing device for example an inhaler device |
| EP1622633B1 (en) | 2003-05-15 | 2016-02-24 | Ampio Pharmaceuticals, Inc. | Treatment of t-cell mediated diseases |
| WO2004101040A1 (en) | 2003-05-16 | 2004-11-25 | University Of Alberta | Add-on spacer design concept for dry-powder inhalers |
| AU155632S (en) | 2003-05-16 | 2004-06-01 | Henkel Kgaa | Blister pack |
| GB0312007D0 (en) | 2003-05-24 | 2003-07-02 | Innovata Biomed Ltd | Container |
| EP1631264B8 (en) | 2003-06-02 | 2017-05-24 | GlaxoSmithKline Biologicals SA | Immunogenic compositions based on microparticles comprising adsorbed toxoid and a polysaccharide-containing antigen |
| CA2528064C (en) | 2003-06-13 | 2010-01-12 | Advanced Inhalation Research, Inc. | Low dose pharmaceutical powders for inhalation |
| US7001622B1 (en) | 2003-06-30 | 2006-02-21 | Robert Berndt | Composition and method for treatment and prevention of pruritis |
| GB0315509D0 (en) | 2003-07-02 | 2003-08-06 | Meridica Ltd | Dispensing device |
| AU158576S (en) | 2003-07-05 | 2006-08-22 | Clinical Designs Ltd | Inhaler |
| US7462367B2 (en) | 2003-07-11 | 2008-12-09 | Boehringer Ingelheim International Gmbh | Anticholinergic powder formulations for inhalation |
| US8921311B2 (en) | 2003-08-01 | 2014-12-30 | Mannkind Corporation | Method for treating hyperglycemia |
| USD569967S1 (en) | 2003-08-06 | 2008-05-27 | Meridica Limited | Inhaler |
| US20050043247A1 (en) | 2003-08-18 | 2005-02-24 | Boehringer Ingelheim International Gmbh | Spray-dried amorphous BIBN 4096, process for preparing and the use thereof as inhalative |
| DE10338402A1 (de) | 2003-08-18 | 2005-03-17 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Sprühgetrocknetes, amorphes BIBN 4096, Verfahren zu dessen Herstellung sowie dessen Verwendung als Inhalativum |
| US20050056535A1 (en) | 2003-09-15 | 2005-03-17 | Makoto Nagashima | Apparatus for low temperature semiconductor fabrication |
| DE10343668A1 (de) | 2003-09-18 | 2005-04-14 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Arzneimittelblister |
| GB2398065A (en) | 2003-10-16 | 2004-08-11 | Bespak Plc | Dispensing apparatus |
| EP1675822A2 (en) | 2003-10-16 | 2006-07-05 | Cara Therapeutics, Inc. | Amide or thioamide derivatives and their use in the treatment of pain |
| USD511208S1 (en) | 2003-10-24 | 2005-11-01 | Valois Sas | Metered dose inhaler |
| US7377277B2 (en) | 2003-10-27 | 2008-05-27 | Oriel Therapeutics, Inc. | Blister packages with frames and associated methods of fabricating dry powder drug containment systems |
| US7451761B2 (en) | 2003-10-27 | 2008-11-18 | Oriel Therapeutics, Inc. | Dry powder inhalers, related blister package indexing and opening mechanisms, and associated methods of dispensing dry powder substances |
| US20070277820A1 (en) | 2003-10-27 | 2007-12-06 | Timothy Crowder | Blister packages and associated methods of fabricating dry powder drug containment systems |
| US20050147581A1 (en) | 2003-11-19 | 2005-07-07 | The Board Of Trustees Of The University Of Illinois | Macromolecular drug complexes having improved stability and therapeutic use of the same |
| SE0303269L (sv) | 2003-12-03 | 2005-06-04 | Microdrug Ag | Medicinsk produkt |
| GB0329884D0 (en) | 2003-12-23 | 2004-01-28 | Glaxo Group Ltd | Method |
| ES2584867T3 (es) | 2004-01-12 | 2016-09-29 | Mannkind Corporation | Un método que reduce los niveles séricos de proinsulina en diabéticos de tipo 2 |
| AU2005209199B2 (en) | 2004-01-16 | 2008-09-11 | Biodel Inc. | Sublingual drug delivery device |
| DE102004006450B4 (de) | 2004-02-05 | 2012-09-27 | Ing. Erich Pfeiffer Gmbh | Dosiervorrichtung |
| DE102004008141A1 (de) | 2004-02-19 | 2005-09-01 | Abbott Gmbh & Co. Kg | Guanidinverbindungen und ihre Verwendung als Bindungspartner für 5-HT5-Rezeptoren |
| USD512777S1 (en) | 2004-02-19 | 2005-12-13 | Chrysalis Technologies Incorporated | Inhaler |
| EP1718354B1 (en) | 2004-02-24 | 2020-04-29 | MicroDose Therapeutx, Inc. | Inhaler with a directional flow sensor |
| JP4708369B2 (ja) | 2004-02-24 | 2011-06-22 | マイクロドース セラピューテクス,インコーポレイテッド | 合成ジェットに基づく薬剤投与装置 |
| DE602005014962D1 (de) * | 2004-03-12 | 2009-07-30 | Biodel Inc | Insulinzusammensetzungen mit verbesserter wirkstoffabsorption |
| ITMO20040060A1 (it) | 2004-03-18 | 2004-06-18 | Roberto Oliva | Inalatore per preparati in polvere |
| USD515696S1 (en) | 2004-03-19 | 2006-02-21 | Innovata Biomed Limited | Inhaler |
| US7625865B2 (en) * | 2004-03-26 | 2009-12-01 | Universita Degli Studi Di Parma | Insulin highly respirable microparticles |
| USD533268S1 (en) | 2004-04-18 | 2006-12-05 | Bahram Olfati | Inhaler |
| JP2007533387A (ja) | 2004-04-21 | 2007-11-22 | イノベータ バイオメド リミテッド | 吸入器 |
| WO2005102428A1 (en) | 2004-04-23 | 2005-11-03 | The Governors Of The University Of Alberta | Enhanced drug delivery for inhaled aerosols |
| AU2005238962B2 (en) | 2004-04-23 | 2011-05-26 | Philip Morris Products S.A. | Aerosol generators and methods for producing aerosols |
| GB0410712D0 (en) | 2004-05-13 | 2004-06-16 | Novartis Ag | Organic compounds |
| USD527817S1 (en) | 2004-05-13 | 2006-09-05 | Novartis Ag | Inhaler |
| US20050265927A1 (en) | 2004-05-17 | 2005-12-01 | Yale University | Intranasal delivery of nucleic acid molecules |
| WO2005113043A1 (en) | 2004-05-19 | 2005-12-01 | Cipla Limited | Medicament inhaler device |
| USD548833S1 (en) | 2004-05-28 | 2007-08-14 | Quadrant Technologies Limited | Dry powder inhaler |
| USD529604S1 (en) | 2004-05-28 | 2006-10-03 | Quadrant Technologies Limited | Dry powder inhaler |
| JP2008501473A (ja) | 2004-06-07 | 2008-01-24 | メデリオ アーゲー | 吸入可能な薬剤のドーズ品質の保証 |
| SE528190C2 (sv) | 2004-06-07 | 2006-09-19 | Mederio Ag | Inhalator |
| US20060000469A1 (en) | 2004-07-02 | 2006-01-05 | Tseng Daniel C | Nebulizing apparatus for medical use with improved nozzle positioning structure |
| JP2008507316A (ja) | 2004-07-23 | 2008-03-13 | インターキュア リミティド | 非接触マイクを使用する呼吸パターン決定のための装置と方法 |
| JP5016486B2 (ja) | 2004-07-26 | 2012-09-05 | 1355540 オンタリオ インコーポレーテッド | 凝集化の少ない粉体吸入器 |
| AU2005271403A1 (en) | 2004-08-03 | 2006-02-16 | Biorexis Pharmaceutical Corporation | Combination therapy using transferrin fusion proteins comprising GLP-1 |
| ATE486064T1 (de) | 2004-08-20 | 2010-11-15 | Mannkind Corp | Katalyse der diketopiperazinsynthese |
| CN101014321A (zh) | 2004-08-23 | 2007-08-08 | 曼金德公司 | 5型磷酸二酯酶抑制剂的肺部给予 |
| KR20130066695A (ko) * | 2004-08-23 | 2013-06-20 | 맨카인드 코포레이션 | 약물 전달용 디케토피페라진염, 디케토모르포린염 또는 디케토디옥산염 |
| GB0419849D0 (en) | 2004-09-07 | 2004-10-13 | Pfizer Ltd | Pharmaceutical combination |
| US8210171B2 (en) | 2004-09-13 | 2012-07-03 | Oriel Therapeutics, Inc. | Tubular dry powder drug containment systems, associated inhalers and methods |
| USD537936S1 (en) | 2004-09-15 | 2007-03-06 | Glaxo Group Limited | Cap with an extension, particularly for a dust cap of a metered dose inhaler |
| USD537522S1 (en) | 2004-09-15 | 2007-02-27 | Glaxo Group Limited | Telescopic strap, particularly for a dust cap of a metered dose inhaler |
| USD518170S1 (en) | 2004-09-28 | 2006-03-28 | Vectura, Ltd. | Inhaler |
| CN101785892B (zh) | 2004-10-06 | 2014-12-10 | 贝林格尔·英格海姆国际有限公司 | 分配装置、存放装置以及分配粉末的方法 |
| US7469696B2 (en) | 2004-10-13 | 2008-12-30 | Hewlett-Packard Development Company, L.P. | Thermal drop generator |
| USD515924S1 (en) | 2004-11-01 | 2006-02-28 | Warner-Lambert Company Llc | Blister card |
| DE102005033398A1 (de) | 2004-11-10 | 2006-05-11 | Alfred Von Schuckmann | Inhalier-Gerät |
| KR20070095927A (ko) | 2004-12-03 | 2007-10-01 | 메데리오 에이지 | 폐 흡입을 위한 글루카곤-형 펩타이드 약제를 포함하는의약품 |
| SE0402976L (sv) | 2004-12-03 | 2006-06-04 | Mederio Ag | Medicinsk produkt |
| GB0427028D0 (en) | 2004-12-09 | 2005-01-12 | Cambridge Consultants | Dry powder inhalers |
| US20060130838A1 (en) | 2004-12-20 | 2006-06-22 | Lee Yong Y | Data logger for monitoring asthmatic conditions |
| KR20070090036A (ko) | 2004-12-22 | 2007-09-04 | 센토코 인코포레이티드 | Glp-1 작용제, 조성물, 방법 및 용도 |
| EP1858486A2 (en) * | 2005-01-10 | 2007-11-28 | MannKind Corporation | Methods and compositions for minimizing accrual of inhalable insulin in the lungs |
| US20060165756A1 (en) * | 2005-01-27 | 2006-07-27 | Catani Steven J | Method for weight management |
| USD538423S1 (en) | 2005-02-04 | 2007-03-13 | Berube-White | Panda bear inhaler |
| GB0503738D0 (en) | 2005-02-23 | 2005-03-30 | Optinose As | Powder delivery devices |
| JP4656397B2 (ja) | 2005-03-31 | 2011-03-23 | 株式会社吉野工業所 | 粉体用容器 |
| CN100431634C (zh) | 2005-04-04 | 2008-11-12 | 陈庆堂 | 干粉气溶胶化吸入器 |
| US7762953B2 (en) | 2005-04-20 | 2010-07-27 | Adidas Ag | Systems and methods for non-invasive physiological monitoring of non-human animals |
| US7694676B2 (en) | 2005-04-22 | 2010-04-13 | Boehringer Ingelheim Gmbh | Dry powder inhaler |
| AU2006241145B2 (en) | 2005-04-27 | 2011-04-28 | Baxter Healthcare S. A. | Surface-modified microparticles and methods of forming and using the same |
| US7219664B2 (en) | 2005-04-28 | 2007-05-22 | Kos Life Sciences, Inc. | Breath actuated inhaler |
| CN101171182A (zh) | 2005-05-02 | 2008-04-30 | 阿斯利康(瑞典)有限公司 | 用于开启凹部的装置和方法、医用密封包及分配设备 |
| USD544093S1 (en) | 2005-06-02 | 2007-06-05 | Bang & Olufsen A/S | Inhaler |
| HUE038177T2 (hu) | 2005-06-17 | 2018-09-28 | Wisconsin Alumni Res Found | Topikális érösszehúzó készítmények és eljárás sejtek védelmére rák kemoterápia és radioterápia alatt |
| EP1901793A1 (en) | 2005-07-13 | 2008-03-26 | Cipla Ltd. | Inhaler device |
| US8763605B2 (en) | 2005-07-20 | 2014-07-01 | Manta Devices, Llc | Inhalation device |
| USD550835S1 (en) | 2005-07-22 | 2007-09-11 | Omron Healthcare Co., Ltd. | Atomizer for inhaler |
| JP2009503093A (ja) * | 2005-08-01 | 2009-01-29 | マンカインド コーポレイション | インスリン産生細胞の機能を保持する方法 |
| JP5694643B2 (ja) | 2005-08-05 | 2015-04-01 | スリーエム イノベイティブ プロパティズ カンパニー | 改善された流動性を示す組成物 |
| CN101313293B (zh) | 2005-08-25 | 2011-06-15 | 奥里尔治疗公司 | 具有棒、相关的包、干粉吸入器的药物贮库系统和方法 |
| US7900625B2 (en) | 2005-08-26 | 2011-03-08 | North Carolina State University | Inhaler system for targeted maximum drug-aerosol delivery |
| EP1928437A2 (en) | 2005-08-26 | 2008-06-11 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation |
| JP2007061281A (ja) | 2005-08-30 | 2007-03-15 | Hitachi Ltd | 吸入量測定システム |
| US20100041612A1 (en) | 2005-09-08 | 2010-02-18 | Martin Beinborn | Fragments of the Glucagon-Like Peptide-1 and Uses Thereof |
| MX373000B (es) | 2005-09-14 | 2020-05-21 | Mannkind Corp | Metodo para formulacion de farmaco basado en el aumento de la afinidad de agentes activos hacia las superficies de microparticulas cristalinas. |
| WO2007041481A1 (en) | 2005-09-29 | 2007-04-12 | Biodel, Inc. | Rapid acting and prolonged acting insulin preparations |
| US20070074989A1 (en) | 2005-09-30 | 2007-04-05 | Musculoskeletal Transplant Foundation | Container for lyophilization and storage of tissue |
| GB0520794D0 (en) | 2005-10-12 | 2005-11-23 | Innovata Biomed Ltd | Inhaler |
| ITMI20051999A1 (it) | 2005-10-21 | 2007-04-22 | Eratech S R L | Formulazioni inalatorie di farmaci in fora di polvere secca per somministrazione come tale o con nebulizzatore e dotate di elevata erogabilita' respirabilita' e stabilita' |
| US8039432B2 (en) | 2005-11-09 | 2011-10-18 | Conjuchem, Llc | Method of treatment of diabetes and/or obesity with reduced nausea side effect |
| AR058289A1 (es) | 2005-12-12 | 2008-01-30 | Glaxo Group Ltd | Colector para ser usado en dispensador de medicamento |
| JP5096363B2 (ja) | 2005-12-16 | 2012-12-12 | ネクター セラピューティックス | Glp−1のポリマ複合体 |
| USD557799S1 (en) | 2006-01-25 | 2007-12-18 | Valois S.A.S. | Inhaler |
| GB0602897D0 (en) | 2006-02-13 | 2006-03-22 | Jagotec Ag | Improvements In Or Relating To Dry Powder Inhaler Devices |
| EP1991840A1 (en) | 2006-02-14 | 2008-11-19 | Battelle Memorial Institute | Accurate metering system |
| CN101389648B (zh) | 2006-02-22 | 2013-07-17 | 默沙东公司 | 肽胃泌酸调节素衍生物 |
| EP1986679B1 (en) | 2006-02-22 | 2017-10-25 | MannKind Corporation | A method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent |
| DE102006010089A1 (de) | 2006-02-24 | 2007-10-18 | Aha-Kunststofftechnik Gmbh | Trockenpulver-Inhalator |
| US8037880B2 (en) | 2006-04-07 | 2011-10-18 | The University Of Western Ontario | Dry powder inhaler |
| EP1844806A1 (de) | 2006-04-13 | 2007-10-17 | Boehringer Ingelheim Pharma GmbH | Medikamenten-Ausgabevorrichtung, Medikamentenmagazin dafür, und Verfahren zur Entnahme eines Medikaments aus einer Medikamentenkammer |
| EP1844809A1 (de) | 2006-04-13 | 2007-10-17 | Boehringer Ingelheim Pharma GmbH & Co. KG | Medikamentenmagazin für einen Inhalator, sowie Mehrdosispulverinhalator |
| US20070243216A1 (en) | 2006-04-14 | 2007-10-18 | Stanley Kepka | Stable solutions of prostaglandin and uses of same |
| MX2008013216A (es) | 2006-04-14 | 2008-10-27 | Mannkind Corp | Formulaciones farmaceuticas de peptido-1 tipo glucagon (glp-1). |
| GR1005620B (el) | 2006-05-09 | 2007-09-03 | Βελτιωση συσκευης εισπνοων ξηρης σκονης | |
| DE102006021978A1 (de) | 2006-05-10 | 2007-11-15 | Robert Bosch Gmbh | Vorrichtung und Verfahen zum Verstärken eines Blisters |
| EP2022445A1 (en) | 2006-05-10 | 2009-02-11 | S.K.I.Net Inc. | Anesthetic system for small animal |
| PT103481B (pt) | 2006-05-16 | 2008-08-01 | Hovione Farmaciencia S A | Inalador de uso simples e método de inalação |
| GB0611659D0 (en) | 2006-06-13 | 2006-07-19 | Cambridge Consultants | Dry powder inhalers |
| GB0611656D0 (en) | 2006-06-13 | 2006-07-19 | Cambridge Consultants | Dry powder inhalers |
| CN101505821A (zh) | 2006-06-16 | 2009-08-12 | 希普拉有限公司 | 改进的干燥粉末吸入器 |
| RU2436599C2 (ru) | 2006-06-27 | 2011-12-20 | Оцука Фармасьютикал Ко., Лтд. | Порошковый ингалятор |
| EP2035068A1 (en) | 2006-06-27 | 2009-03-18 | Brin Tech International Limited | Inhaler |
| GB0613161D0 (en) | 2006-06-30 | 2006-08-09 | Novartis Ag | Organic Compounds |
| CN2917673Y (zh) | 2006-07-06 | 2007-07-04 | 兴安药业有限公司 | 一种胶囊型干粉吸入器 |
| WO2008008021A1 (en) | 2006-07-14 | 2008-01-17 | Astrazeneca Ab | Inhalation system and delivery device for the administration of a drug in the form of dry powder. |
| EP2076242B8 (en) | 2006-07-27 | 2013-02-20 | Nektar Therapeutics | Aerosolizable formulation comprising insulin for pulmonary delivery |
| WO2008014613A1 (en) | 2006-08-04 | 2008-02-07 | Manus Pharmaceuticals (Canada) Ltd. | Multifunctional bioactive compounds |
| GB0616299D0 (en) | 2006-08-16 | 2006-09-27 | Cambridge Consultants | Drug Capsules for dry power inhalers |
| US20080066739A1 (en) | 2006-09-20 | 2008-03-20 | Lemahieu Edward | Methods and systems of delivering medication via inhalation |
| US20080108574A1 (en) | 2006-09-27 | 2008-05-08 | Braincells, Inc. | Melanocortin receptor mediated modulation of neurogenesis |
| US8236766B2 (en) | 2006-11-10 | 2012-08-07 | Cara Therapeutics, Inc. | Uses of synthetic peptide amides |
| US20080173067A1 (en) | 2006-11-10 | 2008-07-24 | Farina Dino J | Automated nasal spray pump testing |
| US7842662B2 (en) | 2006-11-10 | 2010-11-30 | Cara Therapeutics, Inc. | Synthetic peptide amide dimers |
| MX2009005000A (es) | 2006-11-10 | 2009-10-12 | Cara Therapeutics Inc | Amidas de peptidos sinteticos. |
| US7713937B2 (en) | 2006-11-10 | 2010-05-11 | Cara Therapeutics, Inc. | Synthetic peptide amides and dimeric forms thereof |
| US7824014B2 (en) | 2006-12-05 | 2010-11-02 | Canon Kabushiki Kaisha | Head substrate, printhead, head cartridge, and printing apparatus |
| USD548619S1 (en) | 2006-12-06 | 2007-08-14 | Eveready Battery Company, Inc. | Zinc-air hearing aid battery package |
| USD549111S1 (en) | 2006-12-06 | 2007-08-21 | Eveready Battery Company, Inc. | Zinc-air hearing aid battery package |
| USD548618S1 (en) | 2006-12-06 | 2007-08-14 | Eveready Battery Company, Inc. | Zinc-air hearing aid battery package |
| EP2063940B1 (en) | 2006-12-22 | 2012-01-11 | Almirall, S.A. | Inhalation device for drugs in powder form |
| WO2008092864A1 (en) | 2007-01-29 | 2008-08-07 | Novo Nordisk A/S | Method and devices for aerosolizing a drug formulation |
| US8172817B2 (en) | 2007-01-31 | 2012-05-08 | Allegiance Corporation | Liquid collection system and related methods |
| AU2008216265B2 (en) | 2007-02-15 | 2014-04-03 | Indiana University Research And Technology Corporation | Glucagon/GLP-1 receptor co-agonists |
| US8196576B2 (en) | 2007-02-28 | 2012-06-12 | Microdose Therapeutx, Inc. | Inhaler |
| WO2009005546A1 (en) | 2007-03-05 | 2009-01-08 | Board of Governors for Higher Education, State of Rhode Island and the Providence Plantations | High efficiency mouthpiece/adaptor for inhalers |
| JP2008212436A (ja) | 2007-03-06 | 2008-09-18 | Canon Inc | 吸入装置 |
| US8146745B2 (en) | 2007-03-09 | 2012-04-03 | Cardpak, Inc. | Environmentally separable packaging device with attaching base |
| GB0704928D0 (en) | 2007-03-14 | 2007-04-25 | Cambridge Consultants | Dry powder inhalers |
| WO2009076325A2 (en) | 2007-04-11 | 2009-06-18 | Starr Life Sciences Corp. | Noninvasive photoplethysmographic sensor platform for mobile animals |
| JP4417400B2 (ja) | 2007-04-16 | 2010-02-17 | アンリツ株式会社 | はんだ検査ライン集中管理システム、及びそれに用いられる管理装置 |
| HRP20130259T1 (hr) | 2007-04-23 | 2013-04-30 | Intarcia Therapeutics, Inc. | Suspenzijske formulacije inzulinotropnih peptida i njihove uporabe |
| US20100215588A1 (en) | 2007-04-26 | 2010-08-26 | Rami Skaliter | Therapeutic delivery of inhibitory nucleic acid molecules to the respiratory system |
| USD577815S1 (en) | 2007-04-30 | 2008-09-30 | Sun Pharma Advanced Research Company Limited | Inhaler |
| HUE034380T2 (en) | 2007-04-30 | 2018-02-28 | Sun Pharma Advanced Res Co Ltd | Inhalation device |
| USD583463S1 (en) | 2007-04-30 | 2008-12-23 | Sun Pharma Advanced Research Company Limited | Inhaler |
| EP1992378A1 (en) | 2007-05-16 | 2008-11-19 | Boehringer Ingelheim Pharma GmbH & Co. KG | Dispensing device |
| EP2164799B1 (en) | 2007-05-16 | 2018-12-26 | Mystic Pharmaceuticals, Inc. | Combination unit dose dispensing containers |
| USD579546S1 (en) | 2007-06-07 | 2008-10-28 | Novartis Ag | Inhaler |
| JP2010529128A (ja) | 2007-06-08 | 2010-08-26 | マサチューセッツ インスティテュート オブ テクノロジー | レット症候群および他の障害の処置 |
| EP2170350B1 (en) | 2007-06-21 | 2013-09-11 | Cara Therapeutics, Inc. | Substituted imidazoheterocycles |
| EP2170444B1 (en) | 2007-07-06 | 2016-09-07 | Manta Devices, LLC | Inhalation devices for storing and delivering medicament |
| RU2368312C2 (ru) * | 2007-08-28 | 2009-09-27 | Владимир Дмитриевич Чувашов | Способ мониторинга инсулиновой терапии диабета |
| WO2009046072A1 (en) | 2007-10-02 | 2009-04-09 | Baxter International Inc | Dry powder inhaler |
| EP2048112A1 (en) | 2007-10-09 | 2009-04-15 | Kemira Kemi AB | Use of a nozzle for manufacturing sodium percarbonate |
| EP2211842B1 (en) | 2007-10-24 | 2015-08-12 | MannKind Corporation | An inhalable dry powder formulation comprising glp-1 for use in the treatment of hyperglycemia and diabetes by pulmonary administration |
| JP5813323B2 (ja) | 2007-10-24 | 2015-11-17 | マンカインド コーポレイション | 活性薬剤の送達方法 |
| US8785396B2 (en) | 2007-10-24 | 2014-07-22 | Mannkind Corporation | Method and composition for treating migraines |
| AU2008317307A1 (en) | 2007-10-25 | 2009-04-30 | Novartis Ag | Powder conditioning of unit dose drug packages |
| GB0721394D0 (en) | 2007-10-31 | 2007-12-12 | Vectura Group Plc | Compositions for trating parkinson's disease |
| CN101909682B (zh) | 2007-11-06 | 2013-09-18 | 3M创新有限公司 | 药物吸入装置及其部件 |
| CN101317821B (zh) | 2007-11-15 | 2012-01-04 | 陈晓东 | 适用于肺部给药的超细干粉颗粒及其制备方法 |
| EP2060268A1 (en) | 2007-11-15 | 2009-05-20 | Novo Nordisk A/S | Pharmaceutical compositions for pulmonary or nasal delivery of peptides |
| USD594753S1 (en) | 2007-12-14 | 2009-06-23 | The Procter & Gamble Company | Blister card |
| JP5570996B2 (ja) | 2007-12-14 | 2014-08-13 | エアロデザインズ インコーポレイテッド | エアロゾル化可能な食料品の送達 |
| MX2010006657A (es) | 2007-12-20 | 2010-10-05 | Astrazeneca Ab | Dispositivo y metodo para desagregar polvo 854. |
| US7584846B2 (en) | 2007-12-21 | 2009-09-08 | S.C. Johnson & Son, Inc. | Shaped packaging for a refill |
| CA2728808A1 (en) | 2008-02-01 | 2009-08-06 | Vectura Limited | Pulmonary formulations of triptans |
| GB0802028D0 (en) | 2008-02-05 | 2008-03-12 | Dunne Stephen T | Powder inhaler flow regulator |
| USD614045S1 (en) | 2008-02-22 | 2010-04-20 | Ima Safe S.R.L. | Blister packaging |
| WO2009121020A1 (en) | 2008-03-27 | 2009-10-01 | Mannkind Corporation | A dry powder inhalation system |
| JP2011516541A (ja) | 2008-04-07 | 2011-05-26 | ナショナル インスティテュート オブ イミュノロジー | 糖尿病および他の慢性疾患の治療に有用な組成物 |
| DE102008023376A1 (de) | 2008-05-13 | 2009-11-19 | Alfred Von Schuckmann | Spender für in einer gesonderten Verpackung enthaltenen, pulverförmigen Massen |
| WO2009140587A1 (en) | 2008-05-15 | 2009-11-19 | Novartis Ag | Pulmonary delivery of a fluoroquinolone |
| USD597418S1 (en) | 2008-05-22 | 2009-08-04 | Wm. Wrigley Jr. Company | Blister card |
| USD598785S1 (en) | 2008-05-22 | 2009-08-25 | Wm. Wrigley Jr. Company | Blister card |
| USD604832S1 (en) | 2008-06-13 | 2009-11-24 | Mannkind Corporation | Cartridge for a dry powder inhaler |
| USD605753S1 (en) | 2008-06-13 | 2009-12-08 | Mannkind Corporation | Cartridge for a dry powder inhaler |
| USD613849S1 (en) | 2008-06-13 | 2010-04-13 | Mannkind Corporation | Cartridge for a dry powder inhaler |
| USD605752S1 (en) | 2008-06-13 | 2009-12-08 | Mannkind Corporation | Dry powder inhaler |
| CN101827626B (zh) | 2008-06-13 | 2015-03-18 | 曼金德公司 | 干粉吸入器和用于药物输送的系统 |
| USD597657S1 (en) | 2008-06-13 | 2009-08-04 | Mannkind Corporation | Dry powder inhaler |
| USD635241S1 (en) | 2008-06-13 | 2011-03-29 | Mannkind Corporation | Dry powder inhaler |
| USD614760S1 (en) | 2008-06-13 | 2010-04-27 | Mannkind Corporation | Dry powder inhaler |
| US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
| USD604833S1 (en) | 2008-06-13 | 2009-11-24 | Mannkind Corporation | Dry powder inhaler |
| ES2421385T3 (es) | 2008-06-20 | 2013-09-02 | Mannkind Corp | Aparato interactivo y procedimiento para establecer el perfil, en tiempo real, de esfuerzos de inhalación |
| TWI532497B (zh) | 2008-08-11 | 2016-05-11 | 曼凱公司 | 超快起作用胰島素之用途 |
| USD629505S1 (en) | 2008-12-01 | 2010-12-21 | Mannkind Corporation | Dry powder inhaler |
| USD629887S1 (en) | 2008-12-01 | 2010-12-28 | Mannkind Corporation | Dry powder inhaler |
| USD635242S1 (en) | 2008-12-01 | 2011-03-29 | Mannkind Corporation | Dry powder inhaler |
| USD635243S1 (en) | 2008-12-01 | 2011-03-29 | Mannkind Corporation | Dry powder inhaler |
| USD629506S1 (en) | 2008-12-01 | 2010-12-21 | Mannkind Corporation | Dry powder inhaler |
| USD629886S1 (en) | 2008-12-01 | 2010-12-28 | Mannkind Corporation | Dry powder inhaler |
| USD629888S1 (en) | 2008-12-01 | 2010-12-28 | Mannkind Corporation | Dry powder inhaler |
| EP2379511B1 (en) | 2008-12-29 | 2014-12-17 | MannKind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
| US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
| DK2379100T3 (en) | 2009-01-08 | 2014-12-01 | Mannkind Corp | Treatment of hyperglycemia with GLP-1 |
| WO2010083042A1 (en) | 2009-01-15 | 2010-07-22 | Manta Devices, Llc | Delivery device |
| CN102438602B (zh) | 2009-03-04 | 2016-04-13 | 曼金德公司 | 改进的干燥粉末药物输送系统 |
| DK2405963T3 (da) | 2009-03-11 | 2013-12-16 | Mannkind Corp | Apparat, system og fremgangsmåde til at måle modstand i en inhalator |
| CN102355918B (zh) | 2009-03-18 | 2014-07-16 | 曼金德公司 | 用于激光衍射设备的吸入器适配器和用于测量颗粒尺寸分布的方法 |
| GB0907425D0 (en) | 2009-04-29 | 2009-06-10 | Glaxo Group Ltd | Compounds |
| USD628090S1 (en) | 2009-05-07 | 2010-11-30 | Mccormick & Company, Incorporated | Seasoning package |
| USD620375S1 (en) | 2009-05-11 | 2010-07-27 | Mcneil-Ppc, Inc. | Blister |
| CA2762819C (en) | 2009-05-21 | 2016-12-20 | Microdose Therapeutx, Inc. | Rotary cassette system for dry powder inhaler |
| EP3556356B1 (en) | 2009-06-12 | 2021-05-05 | MannKind Corporation | Diketopiperazine microparticles with defined isomer content |
| KR102584844B1 (ko) | 2009-06-12 | 2023-10-04 | 맨카인드 코포레이션 | 한정된 비표면적을 갖는 디케토피페라진 마이크로입자 |
| US9180263B2 (en) | 2009-07-01 | 2015-11-10 | Microdose Therapeutx, Inc. | Laboratory animal pulmonary dosing device |
| EP2482840A4 (en) | 2009-08-07 | 2013-06-26 | Mannkind Corp | VAL (8) GLP-1 COMPOSITION AND METHOD FOR THE TREATMENT OF REAGENTS AND / OR IRRITATION SYNDROME |
| US8962063B2 (en) | 2009-08-27 | 2015-02-24 | St.Unm | Methods and systems for dosing and coating inhalation powders onto carrier particles |
| IT1395945B1 (it) | 2009-09-30 | 2012-11-02 | Oliva | Inalatore perfezionato per preparati in polvere |
| USD647196S1 (en) | 2009-10-09 | 2011-10-18 | Vectura Delivery Devices Limited | Inhaler having cover |
| USD647195S1 (en) | 2009-10-09 | 2011-10-18 | Vectura Delivery Devices Limited | Inhaler having cover |
| CA2778698A1 (en) | 2009-11-03 | 2011-05-12 | Mannkind Corporation | An apparatus and method for simulating inhalation efforts |
| USD650295S1 (en) | 2009-11-13 | 2011-12-13 | Avidiamed Gmbh | Blister pack for pharmaceuticals |
| EP3266462A1 (en) | 2009-12-31 | 2018-01-10 | Stealth Peptides International, Inc. | Methods for performing a coronary artery bypass graft procedure |
| USD641076S1 (en) | 2010-03-26 | 2011-07-05 | Oriel Therapeutics, Inc. | Dry powder inhaler |
| PT105065B (pt) | 2010-04-26 | 2012-07-31 | Hovione Farmaciencia S A | Um inalador simples de cápsulas |
| USD645954S1 (en) | 2010-05-21 | 2011-09-27 | Consort Medical Plc | Mechanical dosage counter apparatus |
| USD636867S1 (en) | 2010-06-14 | 2011-04-26 | Mannkind Corporation | Dry powder inhaler |
| USD636868S1 (en) | 2010-06-14 | 2011-04-26 | Mannkind Corporation | Dry powder inhaler |
| USD636869S1 (en) | 2010-06-14 | 2011-04-26 | Mannkind Corporation | Dry powder inhaler |
| CN102985125A (zh) | 2010-06-21 | 2013-03-20 | 曼金德公司 | 干粉药物输送系统和方法 |
| CN101851213A (zh) | 2010-06-21 | 2010-10-06 | 于清 | 3,6-双(4-双反丁烯二酰基氨丁基)-2,5-二酮哌嗪及其盐取代物的合成方法 |
| US9152829B2 (en) | 2010-08-19 | 2015-10-06 | Sanofi-Aventis Deutschland Gmbh | Method and system for determining information related to a drug reservoir using an electronic sensor |
| USD643308S1 (en) | 2010-09-28 | 2011-08-16 | Mannkind Corporation | Blister packaging |
| EP3470057B1 (en) | 2010-09-29 | 2021-11-03 | Pulmatrix Operating Company, Inc. | Cationic dry powders comprising magnesium salt |
| MX340112B (es) | 2010-11-09 | 2016-06-27 | Mannkind Corp | Composicion que comprende un agonista de receptor de serotonina y una dicetopiperazina para el tratamiento de migrañas. |
| USD642483S1 (en) | 2010-12-03 | 2011-08-02 | Mccormick & Company, Incorporated | Seasoning package |
| MX346331B (es) | 2011-02-10 | 2017-03-15 | Mannkind Corp | Formación de bis-3, 6-(4-aminoalquil) - 2, 5-dicetopiperazina con n protegido. |
| SG194034A1 (en) | 2011-04-01 | 2013-11-29 | Mannkind Corp | Blister package for pharmaceutical cartridges |
| WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
| HUE041858T2 (hu) | 2011-08-01 | 2019-05-28 | Univ Monash | Inhalálásra szolgáló eljárás és kiszerelés |
| USD674893S1 (en) | 2011-10-20 | 2013-01-22 | Mannkind Corporation | Inhaler device |
| MX2014004983A (es) | 2011-10-24 | 2014-09-22 | Mannkid Corp | Metodos y composiciones para tratar dolor. |
| CN102436238B (zh) | 2011-11-03 | 2014-04-16 | 广东轻工职业技术学院 | 基于生产线数据采集及信息管理系统的数据采集方法 |
| AU2013252901B2 (en) | 2012-04-27 | 2017-11-30 | Mannkind Corp | Methods for the synthesis of ethylfumarates and their use as intermediates |
| KR102264177B1 (ko) | 2012-07-12 | 2021-06-11 | 맨카인드 코포레이션 | 건조 분말 약물 전달 시스템 및 방법 |
| US20150231067A1 (en) | 2012-08-29 | 2015-08-20 | Mannkind Corporation | Method and composition for treating hyperglycemia |
| WO2014066856A1 (en) | 2012-10-26 | 2014-05-01 | Mannkind Corporation | Inhalable influenza vaccine compositions and methods |
| CN103110611A (zh) | 2012-12-11 | 2013-05-22 | 苏州惠仁生物科技有限公司 | 吸入剂及其制备方法与普鲁兰糖作为吸入剂载体的应用 |
| EP3587404B1 (en) | 2013-03-15 | 2022-07-13 | MannKind Corporation | Microcrystalline diketopiperazine compositions, methods for preparation and use thereof |
| MX375448B (es) | 2013-07-18 | 2025-03-06 | Mannkind Corp | Composiciones farmacéuticas en polvo seco estables al calor y métodos. |
| EP3030294B1 (en) | 2013-08-05 | 2020-10-07 | MannKind Corporation | Insufflation apparatus |
| GB201319265D0 (en) | 2013-10-31 | 2013-12-18 | Norton Waterford Ltd | Medicament inhaler |
| US10307464B2 (en) | 2014-03-28 | 2019-06-04 | Mannkind Corporation | Use of ultrarapid acting insulin |
| USD771237S1 (en) | 2014-10-02 | 2016-11-08 | Mannkind Corporation | Mouthpiece cover |
| WO2017132601A1 (en) | 2016-01-29 | 2017-08-03 | Mannkind Corporation | Dry powder inhaler |
| JP2019516485A (ja) | 2016-05-19 | 2019-06-20 | マンカインド コーポレイション | 吸入を検出および監視するための機器、システム、および方法 |
-
2009
- 2009-08-10 TW TW103131884A patent/TWI532497B/zh active
- 2009-08-10 TW TW104119356A patent/TWI614024B/zh active
- 2009-08-10 TW TW098126878A patent/TWI494123B/zh not_active IP Right Cessation
- 2009-08-11 JP JP2011523105A patent/JP5869339B2/ja active Active
- 2009-08-11 MY MYPI2014001305A patent/MY165651A/en unknown
- 2009-08-11 EP EP16203266.8A patent/EP3207942B1/en active Active
- 2009-08-11 KR KR1020157034895A patent/KR101847485B1/ko active Active
- 2009-08-11 CA CA2733593A patent/CA2733593C/en active Active
- 2009-08-11 US US12/539,499 patent/US8258095B2/en active Active
- 2009-08-11 AU AU2009283013A patent/AU2009283013B2/en active Active
- 2009-08-11 MX MX2011001372A patent/MX357273B/es active IP Right Grant
- 2009-08-11 BR BRPI0917535A patent/BRPI0917535A8/pt not_active Application Discontinuation
- 2009-08-11 SG SG10202010801RA patent/SG10202010801RA/en unknown
- 2009-08-11 MX MX2014009721A patent/MX375063B/es unknown
- 2009-08-11 SG SG10201509826XA patent/SG10201509826XA/en unknown
- 2009-08-11 CA CA3185780A patent/CA3185780A1/en active Pending
- 2009-08-11 WO PCT/US2009/053443 patent/WO2010021879A2/en not_active Ceased
- 2009-08-11 EP EP09760654A patent/EP2328608A2/en not_active Ceased
- 2009-08-11 US US12/539,459 patent/US8119593B2/en active Active
- 2009-08-11 KR KR1020187009530A patent/KR20180037330A/ko not_active Ceased
- 2009-08-11 ES ES16203266T patent/ES2930673T3/es active Active
- 2009-08-11 RU RU2011109016/15A patent/RU2519706C2/ru active
- 2009-08-11 MY MYPI2011000597A patent/MY156306A/en unknown
- 2009-08-11 KR KR1020117004601A patent/KR20110052664A/ko not_active Ceased
- 2009-08-11 CA CA3022991A patent/CA3022991C/en active Active
-
2011
- 2011-02-04 MX MX2019006731A patent/MX2019006731A/es unknown
-
2012
- 2012-01-17 US US13/351,855 patent/US8623817B2/en active Active
- 2012-01-25 US US13/357,821 patent/US9597374B2/en active Active
-
2013
- 2013-12-10 US US14/102,383 patent/US9943571B2/en active Active
-
2014
- 2014-04-03 RU RU2014113047A patent/RU2688663C2/ru active
-
2015
- 2015-03-25 JP JP2015062033A patent/JP6215862B2/ja active Active
-
2016
- 2016-09-12 AU AU2016228157A patent/AU2016228157B2/en active Active
-
2017
- 2017-02-01 US US15/421,743 patent/US10046031B2/en active Active
- 2017-08-07 JP JP2017152242A patent/JP2017226689A/ja active Pending
-
2018
- 2018-03-02 US US15/910,876 patent/US10857207B2/en active Active
- 2018-06-29 US US16/023,996 patent/US10772935B2/en active Active
- 2018-09-13 AU AU2018229524A patent/AU2018229524A1/en not_active Abandoned
-
2019
- 2019-07-12 JP JP2019129788A patent/JP6914998B2/ja active Active
-
2020
- 2020-08-14 US US16/994,404 patent/US11559569B2/en active Active
- 2020-11-25 US US17/105,399 patent/US11998591B2/en active Active
-
2021
- 2021-07-14 JP JP2021116327A patent/JP2021167342A/ja active Pending
-
2022
- 2022-12-08 US US18/077,742 patent/US12303554B2/en active Active
-
2024
- 2024-03-01 US US18/593,204 patent/US20240197836A1/en active Pending
-
2025
- 2025-04-23 US US19/187,193 patent/US20250249075A1/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20050187749A1 (en) | 2003-10-24 | 2005-08-25 | Judy Singley | Method, system, and computer program for performing carbohydrate/insulin calculation based upon food weight |
| US20070027063A1 (en) | 2004-01-12 | 2007-02-01 | Mannkind Corporation | Method of preserving the function of insulin-producing cells |
Non-Patent Citations (2)
| Title |
|---|
| 2007 대한 당뇨학회 가이드라인(2008.07.01.[2016.01.21. 검색] 인터넷 URL<http://cafe.naver.com/0drug/151>).* |
| Diabetes Care, 제31권, 제11호, 제2177-2182면(2008.08.04.).* |
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| KR101847485B1 (ko) | 초속효성 인슐린의 용도 | |
| AU2013204281C1 (en) | Use of ultrarapid acting insulin | |
| HK1242994A1 (en) | Use of ultrarapid acting insulin |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A107 | Divisional application of patent | ||
| PA0104 | Divisional application for international application |
St.27 status event code: A-0-1-A10-A18-div-PA0104 St.27 status event code: A-0-1-A10-A16-div-PA0104 |
|
| PG1501 | Laying open of application |
St.27 status event code: A-1-1-Q10-Q12-nap-PG1501 |
|
| A201 | Request for examination | ||
| PA0201 | Request for examination |
St.27 status event code: A-1-2-D10-D11-exm-PA0201 |
|
| E902 | Notification of reason for refusal | ||
| PE0902 | Notice of grounds for rejection |
St.27 status event code: A-1-2-D10-D21-exm-PE0902 |
|
| P11-X000 | Amendment of application requested |
St.27 status event code: A-2-2-P10-P11-nap-X000 |
|
| P13-X000 | Application amended |
St.27 status event code: A-2-2-P10-P13-nap-X000 |
|
| R18-X000 | Changes to party contact information recorded |
St.27 status event code: A-3-3-R10-R18-oth-X000 |
|
| R18-X000 | Changes to party contact information recorded |
St.27 status event code: A-3-3-R10-R18-oth-X000 |
|
| E701 | Decision to grant or registration of patent right | ||
| PE0701 | Decision of registration |
St.27 status event code: A-1-2-D10-D22-exm-PE0701 |
|
| A107 | Divisional application of patent | ||
| GRNT | Written decision to grant | ||
| PA0104 | Divisional application for international application |
St.27 status event code: A-0-1-A10-A18-div-PA0104 St.27 status event code: A-0-1-A10-A16-div-PA0104 |
|
| PR0701 | Registration of establishment |
St.27 status event code: A-2-4-F10-F11-exm-PR0701 |
|
| PR1002 | Payment of registration fee |
St.27 status event code: A-2-2-U10-U12-oth-PR1002 Fee payment year number: 1 |
|
| PG1601 | Publication of registration |
St.27 status event code: A-4-4-Q10-Q13-nap-PG1601 |
|
| P22-X000 | Classification modified |
St.27 status event code: A-4-4-P10-P22-nap-X000 |
|
| PR1001 | Payment of annual fee |
St.27 status event code: A-4-4-U10-U11-oth-PR1001 Fee payment year number: 4 |
|
| R18-X000 | Changes to party contact information recorded |
St.27 status event code: A-5-5-R10-R18-oth-X000 |
|
| PR1001 | Payment of annual fee |
St.27 status event code: A-4-4-U10-U11-oth-PR1001 Fee payment year number: 5 |
|
| R18-X000 | Changes to party contact information recorded |
St.27 status event code: A-5-5-R10-R18-oth-X000 |
|
| R18-X000 | Changes to party contact information recorded |
St.27 status event code: A-5-5-R10-R18-oth-X000 |
|
| R18-X000 | Changes to party contact information recorded |
St.27 status event code: A-5-5-R10-R18-oth-X000 |
|
| PR1001 | Payment of annual fee |
St.27 status event code: A-4-4-U10-U11-oth-PR1001 Fee payment year number: 6 |
|
| PR1001 | Payment of annual fee |
St.27 status event code: A-4-4-U10-U11-oth-PR1001 Fee payment year number: 7 |
|
| R18 | Changes to party contact information recorded |
Free format text: ST27 STATUS EVENT CODE: A-5-5-R10-R18-OTH-X000 (AS PROVIDED BY THE NATIONAL OFFICE) |
|
| R18-X000 | Changes to party contact information recorded |
St.27 status event code: A-5-5-R10-R18-oth-X000 |
|
| PR1001 | Payment of annual fee |
St.27 status event code: A-4-4-U10-U11-oth-PR1001 Fee payment year number: 8 |
|
| U11 | Full renewal or maintenance fee paid |
Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-OTH-PR1001 (AS PROVIDED BY THE NATIONAL OFFICE) Year of fee payment: 8 |