JPH0322589B2 - - Google Patents

Info

Publication number
JPH0322589B2
JPH0322589B2 JP56123946A JP12394681A JPH0322589B2 JP H0322589 B2 JPH0322589 B2 JP H0322589B2 JP 56123946 A JP56123946 A JP 56123946A JP 12394681 A JP12394681 A JP 12394681A JP H0322589 B2 JPH0322589 B2 JP H0322589B2
Authority
JP
Japan
Prior art keywords
zone
immunoadsorption
mip
signal
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP56123946A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5763454A (en
Inventor
Kooku Tomu Henrii
Riroi Rorei Jerarudo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syva Co
Original Assignee
Syva Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syva Co filed Critical Syva Co
Publication of JPS5763454A publication Critical patent/JPS5763454A/ja
Publication of JPH0322589B2 publication Critical patent/JPH0322589B2/ja
Granted legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G01N33/54387—Immunochromatographic test strips
    • G01N33/54388—Immunochromatographic test strips based on lateral flow
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/805—Test papers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/968—High energy substrates, e.g. fluorescent, chemiluminescent, radioactive
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/80—Fluorescent dyes, e.g. rhodamine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/807—Apparatus included in process claim, e.g. physical support structures

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
JP56123946A 1980-08-07 1981-08-07 Immuno assay method and assay apparatus Granted JPS5763454A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/176,177 US4366241A (en) 1980-08-07 1980-08-07 Concentrating zone method in heterogeneous immunoassays

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2134266A Division JPH0654317B2 (ja) 1980-08-07 1990-05-25 イムノアッセイ装置

Publications (2)

Publication Number Publication Date
JPS5763454A JPS5763454A (en) 1982-04-16
JPH0322589B2 true JPH0322589B2 (show.php) 1991-03-27

Family

ID=22643311

Family Applications (3)

Application Number Title Priority Date Filing Date
JP56123946A Granted JPS5763454A (en) 1980-08-07 1981-08-07 Immuno assay method and assay apparatus
JP2134266A Expired - Lifetime JPH0654317B2 (ja) 1980-08-07 1990-05-25 イムノアッセイ装置
JP6017069A Expired - Lifetime JP2505979B2 (ja) 1980-08-07 1994-02-14 イムノアッセイ装置

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2134266A Expired - Lifetime JPH0654317B2 (ja) 1980-08-07 1990-05-25 イムノアッセイ装置
JP6017069A Expired - Lifetime JP2505979B2 (ja) 1980-08-07 1994-02-14 イムノアッセイ装置

Country Status (9)

Country Link
US (1) US4366241A (show.php)
EP (1) EP0046004B1 (show.php)
JP (3) JPS5763454A (show.php)
AT (1) ATE10548T1 (show.php)
CA (1) CA1174595A (show.php)
DE (1) DE3167436D1 (show.php)
HK (1) HK15887A (show.php)
MY (1) MY8700300A (show.php)
SG (1) SG89186G (show.php)

Families Citing this family (1252)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5622871A (en) * 1987-04-27 1997-04-22 Unilever Patent Holdings B.V. Capillary immunoassay and device therefor comprising mobilizable particulate labelled reagents
US6630328B2 (en) 1909-07-15 2003-10-07 Genencor International, Inc. Increasing production of proteins in gram-positive microorganisms
US4540659A (en) * 1981-04-17 1985-09-10 Syva Company Simultaneous calibration heterogeneous immunoassay
US4843000A (en) * 1979-12-26 1989-06-27 Syntex (U.S.A.) Inc. Simultaneous calibration heterogeneous immunoassay
US4533629A (en) * 1981-04-17 1985-08-06 Syva Company Simultaneous calibration heterogeneous immunoassay
US5156953A (en) * 1979-12-26 1992-10-20 Syntex (U.S.A.) Inc. Simultaneous calibration heterogeneous immunoassay
US5432057A (en) * 1979-12-26 1995-07-11 Syva Company Simultaneous calibration heterogeneous immunoassay
US4299916A (en) * 1979-12-26 1981-11-10 Syva Company Preferential signal production on a surface in immunoassays
US4849338A (en) * 1982-07-16 1989-07-18 Syntex (U.S.A.) Inc. Simultaneous calibration heterogeneous immunoassay
JPS5782766A (en) * 1980-11-11 1982-05-24 Konishiroku Photo Ind Co Ltd Amynological measuring element
US4774174A (en) * 1981-01-23 1988-09-27 Baxter Travenol Laboratories, Inc. Solid phase system for ligand assay
US4786606A (en) * 1981-01-23 1988-11-22 Baxter Travenol Laboratories, Inc. Solid phase system for ligand assay
US4752562A (en) * 1981-01-23 1988-06-21 Baxter Travenol Laboratories, Inc. Detection of serum antibody and surface antigen by radial partition immunoassay
US4517288A (en) * 1981-01-23 1985-05-14 American Hospital Supply Corp. Solid phase system for ligand assay
US4442204A (en) * 1981-04-10 1984-04-10 Miles Laboratories, Inc. Homogeneous specific binding assay device and preformed complex method
US4447526A (en) * 1981-04-20 1984-05-08 Miles Laboratories, Inc. Homogeneous specific binding assay with carrier matrix incorporating specific binding partner
US5624814A (en) * 1981-08-20 1997-04-29 Becton Dickinson And Company Culture medium and method for culturing body fluids containing antibiotics
CA1209889A (en) * 1981-09-18 1986-08-19 Litai Weng Homogeneous assay on a non-porous surface
US4463090A (en) * 1981-09-30 1984-07-31 Harris Curtis C Cascade amplification enzyme immunoassay
US5073484A (en) * 1982-03-09 1991-12-17 Bio-Metric Systems, Inc. Quantitative analysis apparatus and method
US4654300A (en) * 1982-04-02 1987-03-31 Syntex (U.S.A.) Inc. Fluorescent microbead quenching assay
IL68506A (en) * 1982-05-04 1988-06-30 Syva Co Simultaneous calibration heterogeneous immunoassay method and device and kit for use therein
CA1228811A (en) 1983-05-05 1987-11-03 Robert G. Pergolizzi Assay method utilizing polynucleotide sequences
US4552839A (en) * 1983-08-01 1985-11-12 Syntex (U.S.A.) Inc. Determination of analytes in particle-containing medium
USRE34405E (en) * 1983-08-01 1993-10-12 Abbott Laboratories Determination of analytes in particle-containing medium
US4522786A (en) * 1983-08-10 1985-06-11 E. I. Du Pont De Nemours And Company Multilayered test device for detecting analytes in liquid test samples
EP0149168B1 (en) * 1983-12-19 1991-04-24 Daiichi Pure Chemicals Co. Ltd. Immunoassay
SE446229B (sv) * 1984-01-25 1986-08-18 Syn Tek Ab Sett och anordning for detektering av en analyt i ett prov som bringas att passera en yta till vilken bundits ett emne med specifik affinitet till analyten
US4791056A (en) * 1984-03-27 1988-12-13 Syntex (U.S.A.) Inc. Calibration device for heterogeneous immunoassay
US4632901A (en) * 1984-05-11 1986-12-30 Hybritech Incorporated Method and apparatus for immunoassays
US4624929A (en) * 1984-12-03 1986-11-25 Syntex (U.S.A.) Inc. Sample collector and assay device and method for its use
SE458643B (sv) * 1984-12-07 1989-04-17 Pharmacia Ab Anordning med kolonnelement uppdelat i provparti och referenspatri
DE3445816C1 (de) * 1984-12-15 1986-06-12 Behringwerke Ag, 3550 Marburg Flaechenfoermiges diagnostisches Mittel
US5958790A (en) * 1984-12-20 1999-09-28 Nycomed Imaging As Solid phase transverse diffusion assay
WO1986003839A1 (en) * 1984-12-20 1986-07-03 Cerny Erich H Solid phase diffusion assay
US4740468A (en) * 1985-02-14 1988-04-26 Syntex (U.S.A.) Inc. Concentrating immunochemical test device and method
GB2172704B (en) * 1985-03-18 1988-07-13 Nat Res Dev Antigenically active protein and its use in the diagnosis of gonorrhoea
US5879881A (en) * 1985-04-04 1999-03-09 Hybritech, Incorporated Solid phase system for use in ligand-receptor assays
US4824784A (en) * 1985-04-08 1989-04-25 Hygeia Sciences, Incorporated Chromogenic solution for immunoassay
US4623461A (en) * 1985-05-31 1986-11-18 Murex Corporation Transverse flow diagnostic device
US4670381A (en) * 1985-07-19 1987-06-02 Eastman Kodak Company Heterogeneous immunoassay utilizing horizontal separation in an analytical element
US4806311A (en) * 1985-08-28 1989-02-21 Miles Inc. Multizone analytical element having labeled reagent concentration zone
US4900663A (en) * 1985-09-13 1990-02-13 Environmental Diagnostics, Inc. Test kit for determining the presence of organic materials and method of utilizing same
US5240844A (en) * 1985-09-13 1993-08-31 Wie Siong I Test kit for determining the presence of organic materials and method of utilizing same
US4675300A (en) * 1985-09-18 1987-06-23 The Board Of Trustees Of The Leland Stanford Junior University Laser-excitation fluorescence detection electrokinetic separation
TW203120B (show.php) * 1985-10-04 1993-04-01 Abbott Lab
US5501949A (en) * 1985-12-10 1996-03-26 Murex Diagnostics Corporation Particle bound binding component immunoassay
DE3543749A1 (de) * 1985-12-11 1987-06-19 Boehringer Mannheim Gmbh Verfahren zur herstellung eines reagenzpapieres fuer die immunologische analyse
US4868108A (en) * 1985-12-12 1989-09-19 Hygeia Sciences, Incorporated Multiple-antibody detection of antigen
EP0250557A4 (en) * 1985-12-12 1990-01-11 Dennison Mfg Co DETERMINATION OF TEST SUBSTANCES.
US5273877A (en) * 1985-12-24 1993-12-28 Massachusetts Institute Of Technology Non-histological cell type determination
US5160701A (en) * 1986-02-18 1992-11-03 Abbott Laboratories Solid-phase analytical device and method for using same
US4916056A (en) * 1986-02-18 1990-04-10 Abbott Laboratories Solid-phase analytical device and method for using same
JPS62231168A (ja) * 1986-03-21 1987-10-09 ハイブリテツク・インコ−ポレイテツド アナライト−レセプタ−分析用内部標準を設けるための改良法
US4937188A (en) * 1986-04-15 1990-06-26 Northeastern University Enzyme activity amplification method for increasing assay sensitivity
US5190864A (en) * 1986-04-15 1993-03-02 Northeastern University Enzyme amplification by using free enzyme to release enzyme from an immobilized enzyme material
US4851210A (en) * 1986-05-22 1989-07-25 Genelabs Incorporated Blood typing device
AU7033787A (en) * 1986-05-30 1987-12-22 Quidel Enzyme immunoassay device
AU602694B2 (en) * 1986-06-09 1990-10-25 Ortho Diagnostic Systems Inc. Improved colloidal gold membrane assay
US4915812A (en) * 1986-06-20 1990-04-10 Molecular Devices Corporation Zero volume cell
CA1283447C (en) * 1986-06-20 1991-04-23 John W. Parce Zero volume electrochemical cell
US5120504A (en) * 1986-07-14 1992-06-09 Hybritech Incorporated Apparatus for immunoassays with vent chennels in the container side wall
US4935346A (en) 1986-08-13 1990-06-19 Lifescan, Inc. Minimum procedure system for the determination of analytes
US4790979A (en) * 1986-08-29 1988-12-13 Technimed Corporation Test strip and fixture
US4959307A (en) * 1986-09-05 1990-09-25 Syntex (U.S.A.) Inc. Immunoseparating strip
US5260194A (en) * 1986-09-05 1993-11-09 Syntex (U.S.A.) Inc. Immunoseparating strip
US5085988A (en) * 1986-09-05 1992-02-04 Syntex (U.S.A.) Inc. Immunoseparating strip
US4963468A (en) * 1986-09-05 1990-10-16 Syntex (U.S.A.) Inc. Immunoseparating strip
US5260193A (en) * 1986-09-05 1993-11-09 Syntex (U.S.A.) Inc. Immunoseparating strip
US20010023075A1 (en) * 1992-04-03 2001-09-20 Siu-Yin Wong A immunodiagnositc device having a dessicant incorporated therein
US5763262A (en) * 1986-09-18 1998-06-09 Quidel Corporation Immunodiagnostic device
DE3636060C3 (de) * 1986-10-23 1994-04-07 Behringwerke Ag Bioaffine poröse Festphase, Verfahren zu deren Herstellung und ihre Verwendung
EP0264804B1 (de) * 1986-10-23 1993-08-04 BEHRINGWERKE Aktiengesellschaft Bioaffine poröse Festphasen, ein Verfahren zur Herstellung von bioaffinen porösen Festphasen und ihre Verwendung
EP0271204A3 (en) * 1986-11-07 1989-10-25 Syntex (U.S.A.) Inc. Immunochromatographic method and device
US5030558A (en) * 1986-11-07 1991-07-09 Syntex (U.S.A.) Inc. Qualitative immunochromatographic method and device
JPH01501819A (ja) * 1986-11-13 1989-06-22 ジェネ　ラブス，インコーポレイティド 血液親和性診断方法
US4978502A (en) * 1987-01-05 1990-12-18 Dole Associates, Inc. Immunoassay or diagnostic device and method of manufacture
US4769333A (en) * 1987-01-05 1988-09-06 Dole Associates, Inc. Personal diagnostic kit
US4859603A (en) * 1987-01-05 1989-08-22 Dole Associates, Inc. Personal diagnostic kit
US5079142A (en) * 1987-01-23 1992-01-07 Synbiotics Corporation Orthogonal flow immunoassays and devices
US4920046A (en) * 1987-02-20 1990-04-24 Becton, Dickinson And Company Process, test device, and test kit for a rapid assay having a visible readout
US4833087A (en) * 1987-02-27 1989-05-23 Eastman Kodak Company Disposable container configured to produce uniform signal
US5250412A (en) * 1987-03-23 1993-10-05 Diamedix Corporation Swab device and method for collecting and analyzing a sample
US4849340A (en) * 1987-04-03 1989-07-18 Cardiovascular Diagnostics, Inc. Reaction system element and method for performing prothrombin time assay
US4857453A (en) * 1987-04-07 1989-08-15 Syntex (U.S.A.) Inc. Immunoassay device
ES2184734T3 (es) 1987-04-27 2003-04-16 Inverness Medical Switzerland Dispositivo de prueba analitica para realizar ensayos de union especifica.
US4973549A (en) * 1987-06-22 1990-11-27 Chemtrak Corporation Quantitative diagnostic assay employing signal producing agent bound to support and measuring migration distance of detectable signal
US5120643A (en) * 1987-07-13 1992-06-09 Abbott Laboratories Process for immunochromatography with colloidal particles
WO1989001626A1 (fr) * 1987-08-19 1989-02-23 Flemming Gmbh Procede et dispositif de depistage d'un antigene ou d'un anticorps dans un specimen liquide
US4981786A (en) * 1987-09-04 1991-01-01 Syntex (U.S.A.) Inc. Multiple port assay device
DE3730059A1 (de) * 1987-09-08 1989-03-30 Behringwerke Ag Verfahren zur bestimmung von "loeslichem" fibrin
ATE86746T1 (de) * 1987-09-11 1993-03-15 Abbott Lab Geraet fuer die laterale immunochromatographische bestimmung.
US4956302A (en) * 1987-09-11 1990-09-11 Abbott Laboratories Lateral flow chromatographic binding assay device
US5006464A (en) * 1987-10-01 1991-04-09 E-Y Laboratories, Inc. Directed flow diagnostic device and method
FR2621393B1 (fr) * 1987-10-05 1991-12-13 Toledano Jacques Dispositif de detection immunoenzymatique de substances a partir d'une goutte de sang ou de liquide provenant d'un quelconque milieu biologique
US4999163A (en) * 1987-10-29 1991-03-12 Hygeia Sciences, Inc. Disposable, pre-packaged device for conducting immunoassay procedures
US4943525A (en) * 1987-11-02 1990-07-24 Bioventures, Inc. Simultaneous immunoassay for the determination of antigens and antibodies
US5256372A (en) * 1987-11-06 1993-10-26 Idexx Corporation Dipstick test device including a removable filter assembly
US4818677A (en) * 1987-12-03 1989-04-04 Monoclonal Antibodies, Inc. Membrane assay using focused sample application
JPH0630628B2 (ja) * 1987-12-16 1994-04-27 キング醸造株式会社 生細胞数及び活力の測定方法
US5206177A (en) * 1988-01-21 1993-04-27 Boehringer Mannheim Corporation Apparatus for determining an analyte and method therefor
US4963325A (en) * 1988-05-06 1990-10-16 Hygeia Sciences, Inc. Swab expressor immunoassay device
US5374524A (en) * 1988-05-10 1994-12-20 E. I. Du Pont De Nemours And Company Solution sandwich hybridization, capture and detection of amplified nucleic acids
US5137804A (en) * 1988-05-10 1992-08-11 E. I. Du Pont De Nemours And Company Assay device and immunoassay
US5164294A (en) * 1988-05-17 1992-11-17 Syntex (U.S.A.) Inc. Method for immunochromatographic analysis
US5039607A (en) * 1988-05-17 1991-08-13 Syntex (U.S.A.) Inc. Method for immunochromatographic analysis
US5334513A (en) * 1988-05-17 1994-08-02 Syntex (U.S.A.) Inc. Method for immunochromatographic analysis
US5573919A (en) * 1988-06-02 1996-11-12 Carter-Wallace Assay using an absorbent material
US5620845A (en) * 1988-06-06 1997-04-15 Ampcor, Inc. Immunoassay diagnostic kit
AU2684488A (en) 1988-06-27 1990-01-04 Carter-Wallace, Inc. Test device and method for colored particle immunoassay
US5059522A (en) * 1988-08-18 1991-10-22 Wayne Lawrence G Intrinsic enzyme dot blot immunoassay or indentification of microorganisms
US6306594B1 (en) 1988-11-14 2001-10-23 I-Stat Corporation Methods for microdispensing patterened layers
EP0442872A4 (en) * 1988-11-14 1992-08-05 Idexx Corp. Dual absorbent analyte detection
US5200051A (en) * 1988-11-14 1993-04-06 I-Stat Corporation Wholly microfabricated biosensors and process for the manufacture and use thereof
US5939272A (en) * 1989-01-10 1999-08-17 Biosite Diagnostics Incorporated Non-competitive threshold ligand-receptor assays
US5028535A (en) * 1989-01-10 1991-07-02 Biosite Diagnostics, Inc. Threshold ligand-receptor assay
US5252293A (en) * 1989-01-17 1993-10-12 Vladimir Drbal Analytical slide with porous filter membrane
US6352862B1 (en) 1989-02-17 2002-03-05 Unilever Patent Holdings B.V. Analytical test device for imuno assays and methods of using same
ES2104566T3 (es) * 1989-03-10 1997-10-16 Hoffmann La Roche Reactivos para la determinacion de drogas.
US5106761A (en) * 1989-03-13 1992-04-21 International Canine Genetics, Inc. Method for detecting molecules in a liquid medium
US5340539A (en) * 1989-03-16 1994-08-23 Chemtrak, Inc. Non-instrumented cholesterol assay
JPH03215745A (ja) * 1989-07-17 1991-09-20 Univ Rockefeller エストロゲン代謝変化による病理状態検出方法、及び検出のための試験キット
US5155049A (en) * 1989-08-22 1992-10-13 Terrapin Technologies, Inc. Blotting technique for membrane assay
US5185127A (en) * 1989-09-21 1993-02-09 Becton, Dickinson And Company Test device including flow control means
US5075078A (en) * 1989-10-05 1991-12-24 Abbott Laboratories Self-performing immunochromatographic device
US5376556A (en) * 1989-10-27 1994-12-27 Abbott Laboratories Surface-enhanced Raman spectroscopy immunoassay
US5147780A (en) * 1989-12-01 1992-09-15 Sangstat Medical Corporation Multiwell stat test
US5646046A (en) * 1989-12-01 1997-07-08 Akzo Nobel N.V. Method and instrument for automatically performing analysis relating to thrombosis and hemostasis
US5252496A (en) 1989-12-18 1993-10-12 Princeton Biomeditech Corporation Carbon black immunochemical label
US5141850A (en) * 1990-02-07 1992-08-25 Hygeia Sciences, Inc. Porous strip form assay device method
JP3070764B2 (ja) * 1990-03-12 2000-07-31 バイオサイト・ダイアグノスティックス・インコーポレイテッド 生物学的検定装置及びそれを用いた検定方法
US5922615A (en) * 1990-03-12 1999-07-13 Biosite Diagnostics Incorporated Assay devices comprising a porous capture membrane in fluid-withdrawing contact with a nonabsorbent capillary network
US5559032A (en) * 1990-06-29 1996-09-24 Pomeroy; Patrick C. Method and apparatus for post-transfer assaying of material on solid support
US5158869A (en) * 1990-07-06 1992-10-27 Sangstat Medical Corporation Analyte determination using comparison of juxtaposed competitive and non-competitive elisa results and device therefore
AU658374B2 (en) * 1990-09-14 1995-04-13 Biosite Diagnostics Incorporated Antibodies to complexes of ligand receptors and ligands and their utility in ligand-receptor assays
US5143852A (en) * 1990-09-14 1992-09-01 Biosite Diagnostics, Inc. Antibodies to ligand analogues and their utility in ligand-receptor assays
JP2628792B2 (ja) * 1990-09-26 1997-07-09 アカーズ・リサーチ・コーポレーシヨン 改良されたリガンドのアッセイ
US5231035A (en) * 1991-01-11 1993-07-27 Akers Research Corporation Latex agglutination assay
US5607863A (en) * 1991-05-29 1997-03-04 Smithkline Diagnostics, Inc. Barrier-controlled assay device
US5468648A (en) * 1991-05-29 1995-11-21 Smithkline Diagnostics, Inc. Interrupted-flow assay device
US6168956B1 (en) 1991-05-29 2001-01-02 Beckman Coulter, Inc. Multiple component chromatographic assay device
US5998220A (en) 1991-05-29 1999-12-07 Beckman Coulter, Inc. Opposable-element assay devices, kits, and methods employing them
US5869345A (en) * 1991-05-29 1999-02-09 Smithkline Diagnostics, Inc. Opposable-element assay device employing conductive barrier
US5877028A (en) 1991-05-29 1999-03-02 Smithkline Diagnostics, Inc. Immunochromatographic assay device
US5264589A (en) * 1991-06-06 1993-11-23 Miles Inc. Merocyanine protein error indicators
DE4121493A1 (de) * 1991-06-28 1993-01-07 Draegerwerk Ag Analysevorrichtung zur quantitativen, immunologischen bestimmung von schadstoffen
US5451504A (en) * 1991-07-29 1995-09-19 Serex, Inc. Method and device for detecting the presence of analyte in a sample
US6007999A (en) * 1991-07-31 1999-12-28 Idexx Laboratories, Inc. Reversible flow chromatographic binding assay
US5726010A (en) * 1991-07-31 1998-03-10 Idexx Laboratories, Inc. Reversible flow chromatographic binding assay
DK0610356T3 (da) * 1991-10-18 2001-02-19 Synsorb Biotech Inc Behandling af bakteriel dysenteri
WO1993015230A1 (en) * 1992-01-22 1993-08-05 Abbott Laboratories Calibration reagents for semi-quantitative binding assays and devices
WO1993018398A1 (en) * 1992-03-10 1993-09-16 Quidel Corporation Red blood cell separation means for specific binding assays
WO1993021530A1 (de) * 1992-04-10 1993-10-28 Messerschmitt-Bölkow-Blohm Gmbh Verfahren und vorrichtung zur empfindlichkeits- und selektivitätssteigerung bei immuno-assays, molekül-rezeptor-, dna-komplementär-dna- und gast-wirtsmolekül-wechselwirkungs-assays
US5395754A (en) * 1992-07-31 1995-03-07 Hybritech Incorporated Membrane-based immunoassay method
US5447838A (en) * 1992-08-05 1995-09-05 Hybritech Incorporated Protein-dye conjugate for confirmation of correct dilution of calibrators
EP0583980A1 (en) * 1992-08-20 1994-02-23 Eli Lilly And Company Method for generating monoclonal antibodies from rabbits
US5354692A (en) * 1992-09-08 1994-10-11 Pacific Biotech, Inc. Analyte detection device including a hydrophobic barrier for improved fluid flow
AU670108B2 (en) 1992-09-11 1996-07-04 Becton Dickinson & Company Improved antibodies to plasmodium falciparum
FI92882C (fi) * 1992-12-29 1995-01-10 Medix Biochemica Ab Oy Kertakäyttöinen testiliuska ja menetelmä sen valmistamiseksi
US5344754A (en) * 1993-01-13 1994-09-06 Avocet Medical, Inc. Assay timed by electrical resistance change and test strip
US5500375A (en) * 1993-04-13 1996-03-19 Serex, Inc. Integrated packaging-holder device for immunochromatographic assays in flow-through or dipstick formats
US6562333B1 (en) 1993-06-14 2003-05-13 Schering Corporation Purified mammalian CTLA-8 antigens and related reagents
US5684144A (en) * 1993-07-28 1997-11-04 University Of North Texas Escherichia coli csrA gene, protein encoded thereby, and methods of use thereof
US5837546A (en) * 1993-08-24 1998-11-17 Metrika, Inc. Electronic assay device and method
US5770389A (en) * 1993-09-27 1998-06-23 Abbott Laboratories Apparatus and method for determining the quanity of an analyte in a biological sample by means of transmission photometry
US5695928A (en) 1993-12-10 1997-12-09 Novartis Corporation Rapid immunoassay for detection of antibodies or antigens incorporating simultaneous sample extraction and immunogenic reaction
US5561045A (en) * 1994-01-04 1996-10-01 Intracel Corporation Detection reagent, article, and immunoassay method
US5547833A (en) * 1994-01-04 1996-08-20 Intracel Corporation Radial flow assay, delivering member, test kit, and methods
US6406855B1 (en) 1994-02-17 2002-06-18 Maxygen, Inc. Methods and compositions for polypeptide engineering
US6335160B1 (en) 1995-02-17 2002-01-01 Maxygen, Inc. Methods and compositions for polypeptide engineering
USD361842S (en) 1994-05-23 1995-08-29 Carter Wallace, Inc. Immunoassay test cartridge
US5550032A (en) * 1994-05-27 1996-08-27 George Mason University Biological assay for microbial contamination
ES2154712T5 (es) 1994-08-12 2009-12-14 The University Of Utah Research Foundation Metodo para diagnosticar la predisposicion al cancer de mama y de ovarios.
CA2196797C (en) 1994-08-12 2000-10-10 Donna M. Shattuck-Eidens In vivo mutations and polymorphisms in the 17q-linked breast and ovarian cancer susceptibility gene
US6974666B1 (en) * 1994-10-21 2005-12-13 Appymetric, Inc. Methods of enzymatic discrimination enhancement and surface-bound double-stranded DNA
US8236493B2 (en) 1994-10-21 2012-08-07 Affymetrix, Inc. Methods of enzymatic discrimination enhancement and surface-bound double-stranded DNA
JP3010699U (ja) * 1994-10-29 1995-05-02 株式会社ニッポンジーン 直接採尿の可能なクロマト式検査装置
US5633149A (en) 1994-12-07 1997-05-27 Incyte Pharmaceuticals, Inc. Polynucleotide encoding novel chemokine expressed in inflamed adenoid
USD369868S (en) 1995-01-31 1996-05-14 Carter-Wallace, Inc. Immunoassay test cartridge
US7005509B1 (en) 1995-02-17 2006-02-28 Incyte Corporation Chemokine PANEC-1 polynucleotides and compositions and methods related thereto
US5712172A (en) 1995-05-18 1998-01-27 Wyntek Diagnostics, Inc. One step immunochromatographic device and method of use
US5739041A (en) * 1995-05-02 1998-04-14 Carter Wallace, Inc. Diagnostic detection device
US6319676B1 (en) 1995-05-02 2001-11-20 Carter Wallace, Inc. Diagnostic detection device and method
GB0112226D0 (en) * 2001-05-18 2001-07-11 Danisco Method of improving dough and bread quality
US5977322A (en) 1995-06-14 1999-11-02 The Regents Of The University Of California High affinity human antibodies to tumor antigens
US7635597B2 (en) 1995-08-09 2009-12-22 Bayer Healthcare Llc Dry reagent particle assay and device having multiple test zones and method therefor
WO1997006439A1 (en) 1995-08-09 1997-02-20 Quidel Corporation Test strip and method for one step lateral flow assay
US7455964B1 (en) 1996-07-15 2008-11-25 The Hospital For Sick Children Genes from the 20q13 amplicon and their uses
ATE230759T1 (de) 1995-12-18 2003-01-15 Myriad Genetics Inc Chromosom 13 verbundene brustkrebsempfindlichkeitsgen brca2
US5837492A (en) 1995-12-18 1998-11-17 Myriad Genetics, Inc. Chromosome 13-linked breast cancer susceptibility gene
US6864059B2 (en) * 1996-01-23 2005-03-08 Affymetrix, Inc. Biotin containing C-glycoside nucleic acid labeling compounds
US7291463B2 (en) * 1996-01-23 2007-11-06 Affymetrix, Inc. Nucleic acid labeling compounds
US7282327B2 (en) * 1996-01-23 2007-10-16 Affymetrix, Inc. Nucleic acid labeling compounds
US20040210045A1 (en) * 1996-01-23 2004-10-21 Mcgall Glenn Nucleic acid labeling compounds
US20010018514A1 (en) * 1998-07-31 2001-08-30 Mcgall Glenn H. Nucleic acid labeling compounds
EP0880598A4 (en) 1996-01-23 2005-02-23 Affymetrix Inc RAPID EVALUATION OF NUCLEIC ACID ABUNDANCE DIFFERENCE, WITH A HIGH-DENSITY OLIGONUCLEOTIDE SYSTEM
US6965020B2 (en) 1996-01-23 2005-11-15 Affymetrix, Inc. Nucleic acid labeling compounds
US7423143B2 (en) * 1996-01-23 2008-09-09 Affymetrix. Inc. Nucleic acid labeling compounds
US5851777A (en) * 1996-02-05 1998-12-22 Dade Behring Inc. Homogeneous sol-sol assay
EP1728875A3 (en) 1996-02-08 2007-05-09 Affymetrix, Inc. Chip-based speciation and phenotypic characterization of microorganisms
US6228575B1 (en) 1996-02-08 2001-05-08 Affymetrix, Inc. Chip-based species identification and phenotypic characterization of microorganisms
US6924094B1 (en) * 1996-02-08 2005-08-02 Affymetrix, Inc. Chip-based species identification and phenotypic characterization of microorganisms
US5741647A (en) * 1996-02-16 1998-04-21 Tam; Joseph Wing On Flow through nucleic acid hybridisation uses thereof and a device thereof
US6129917A (en) * 1996-03-22 2000-10-10 The University Of Georgia Research Foundation, Inc. Immunogenic compositions comprising porphyromonas gingivalis proteins and/or peptides and methods
US5882644A (en) * 1996-03-22 1999-03-16 Protein Design Labs, Inc. Monoclonal antibodies specific for the platelet derived growth factor β receptor and methods of use thereof
US5968839A (en) * 1996-05-13 1999-10-19 Metrika, Inc. Method and device producing a predetermined distribution of detectable change in assays
AU725238B2 (en) 1996-05-22 2000-10-12 Viventia Biotech Inc. Antigen binding fragments that specifically detect cancer cells, nucleotides encoding the fragments, and use thereof for the prophylaxis and detection of cancers
US6342349B1 (en) 1996-07-08 2002-01-29 Burstein Technologies, Inc. Optical disk-based assay devices and methods
US20050214827A1 (en) * 1996-07-08 2005-09-29 Burstein Technologies, Inc. Assay device and method
ATE397660T1 (de) 1996-08-16 2008-06-15 Schering Corp Zelloberflächen-antigen aus säugetieren und verwandte reagenzien
US5945345A (en) * 1996-08-27 1999-08-31 Metrika, Inc. Device for preventing assay interference using silver or lead to remove the interferant
WO1998013493A2 (en) * 1996-09-24 1998-04-02 Lxr Biotechnology, Inc. A family of genes encoding apoptosis-related peptides, peptides encoded thereby and methods of use thereof
US20070299005A1 (en) * 1996-09-24 2007-12-27 Tanox, Inc. Family of genes encoding apoptosis-related peptides, peptides encoded thereby and methods of use thereof
US5998221A (en) * 1996-09-25 1999-12-07 Becton, Dickinson And Company Non-instrumented assay with quantitative and qualitative results
US7585622B1 (en) * 1996-10-01 2009-09-08 Geron Corporation Increasing the proliferative capacity of cells using telomerase reverse transcriptase
GB2321642B8 (en) 1996-10-01 2006-08-22 Geron Corp Human telomerase reverse transcriptase promoter
US6808880B2 (en) * 1996-10-01 2004-10-26 Geron Corporation Method for detecting polynucleotides encoding telomerase
US6261836B1 (en) 1996-10-01 2001-07-17 Geron Corporation Telomerase
US6610839B1 (en) 1997-08-14 2003-08-26 Geron Corporation Promoter for telomerase reverse transcriptase
US6093809A (en) 1996-10-01 2000-07-25 University Technology Corporation Telomerase
US6475789B1 (en) * 1996-10-01 2002-11-05 University Technology Corporation Human telomerase catalytic subunit: diagnostic and therapeutic methods
GB9907461D0 (en) 1999-03-31 1999-05-26 King S College London Neurite regeneration
US5710005A (en) * 1996-10-29 1998-01-20 Biocode, Inc. Analyte detection with a gradient lateral flow device
EP1803816A3 (en) 1996-12-13 2007-09-26 Schering Corporation Mammalian cell surface antigens; related reagents
US5879951A (en) * 1997-01-29 1999-03-09 Smithkline Diagnostics, Inc. Opposable-element assay device employing unidirectional flow
PT966533E (pt) 1997-02-07 2010-01-26 Univ Ramot Factor neurotrófico iii dependente da actividade (adnf iii)
CA2286910A1 (en) 1997-03-05 1998-09-11 Raouf A. Guirguis Fluid specimen collecting and testing apparatus
US20050013825A1 (en) * 1997-04-18 2005-01-20 Geron Corporation Vaccine containing the catalytic subunit of telomerase for treating cancer
US7413864B2 (en) * 1997-04-18 2008-08-19 Geron Corporation Treating cancer using a telomerase vaccine
US7622549B2 (en) * 1997-04-18 2009-11-24 Geron Corporation Human telomerase reverse transcriptase polypeptides
US6103536A (en) * 1997-05-02 2000-08-15 Silver Lake Research Corporation Internally referenced competitive assays
DK1798288T3 (da) 1997-05-07 2010-01-04 Schering Corp Humane Toll-lignende receptorproteiner, relaterede reagenser og fremgangsmåder
US5939252A (en) * 1997-05-09 1999-08-17 Lennon; Donald J. Detachable-element assay device
US7115722B1 (en) 1997-05-22 2006-10-03 Viventia Biotech, Inc. Antigen binding fragments that specifically detect cancer cells, nucleotides encoding the fragments, and use thereof for the prophylaxis and detection of cancers
US6258548B1 (en) 1997-06-05 2001-07-10 A-Fem Medical Corporation Single or multiple analyte semi-quantitative/quantitative rapid diagnostic lateral flow test system for large molecules
US20020122807A1 (en) * 1998-07-07 2002-09-05 Dan Michael D. Antigen binding fragments, designated 4B5, that specifically detect cancer cells, nucleotides encoding the fragments, and use thereof for the prophylaxis and detection of cancers
ZA986051B (en) 1997-07-09 1999-01-18 Schering Corp Isolated mammalian membrane protein genes related reagents
US6228638B1 (en) 1997-07-11 2001-05-08 University Of North Texas, Health Science Center At Fort Worth Escherichia coli CSRB gene and RNA encoded thereby
US20030157642A1 (en) * 1997-07-15 2003-08-21 Caldwell Robert M. Increasing production of proteins in gram-positive microorganisms
US6723550B1 (en) * 1997-07-15 2004-04-20 Genencor International, Inc. Proteases from gram-positive organisms
US6506579B1 (en) 1997-07-15 2003-01-14 Genencor International, Inc. Increasing production of proteins in gram-positive microorganisms using SecG
US6762039B2 (en) * 1997-07-15 2004-07-13 Genencor International, Inc. Bacillus subtillis with an inactivated cysteine protease-1
US6521421B1 (en) * 1997-07-16 2003-02-18 Genencor International, Inc. Expression vectors encoding Bacillus subtilis disulfide bond isomerase and methods of secreting proteins in gram-positive microorganisms using the same
PE20000183A1 (es) 1997-07-25 2000-03-11 Schering Corp Citoquinas de mamiferos y reactivos relacionados
US6180411B1 (en) 1997-08-01 2001-01-30 The Regents Of The University Of California Light-triggered indicators that memorize analyte concentrations
JP2001512017A (ja) 1997-08-01 2001-08-21 シェーリング コーポレイション 哺乳動物細胞膜タンパク質；関連試薬
US6960457B1 (en) * 1997-09-04 2005-11-01 Stanford University Reversible immobilization of arginine-tagged moieties on a silicate surface
US7252950B1 (en) 1997-09-04 2007-08-07 The Regents Of The University Of California Assays for detecting modulators of cytoskeletal function
US6521440B1 (en) * 1997-09-15 2003-02-18 Genencor International, Inc. Proteases from gram-positive organisms
US6300117B1 (en) * 1997-09-15 2001-10-09 Genencor International, Inc. Proteases from gram-positive organisms
US7378244B2 (en) * 1997-10-01 2008-05-27 Geron Corporation Telomerase promoters sequences for screening telomerase modulators
US6316241B1 (en) * 1997-11-20 2001-11-13 Genencor International, Inc. Alpha/beta hydrolase-fold enzymes
GB9724629D0 (en) * 1997-11-20 1998-01-21 Genencor Int Bv Alpha/beta hydrolase-fold enzymes
GB9724627D0 (en) 1997-11-20 1998-01-21 Genencor Int Bv Gram positive microorganism formate pathway
GB9726398D0 (en) 1997-12-12 1998-02-11 Isis Innovation Polypeptide and coding sequences
US6599731B1 (en) * 1997-12-30 2003-07-29 Genencor International, Inc. Proteases from gram positive organisms
US6528255B1 (en) * 1997-12-30 2003-03-04 Genencor International, Inc. Proteases from gram positive organisms
GB9727470D0 (en) * 1997-12-30 1998-02-25 Genencor Int Bv Proteases from gram positive organisms
US6465186B1 (en) * 1997-12-30 2002-10-15 Genecor International, Inc. Proteases from gram positive organisms
US6780609B1 (en) 1998-10-23 2004-08-24 Genome Therapeutics Corporation High bone mass gene of 1.1q13.3
US6759243B2 (en) 1998-01-20 2004-07-06 Board Of Trustees Of The University Of Illinois High affinity TCR proteins and methods
US6673914B1 (en) 1998-01-22 2004-01-06 John Wayne Cancer Institute Human tumor-associated gene
US6764830B1 (en) 1998-01-23 2004-07-20 The Regents Of The University Of California Thermomyces lanuginosus kinesin motor protein and methods of screening for modulators of kinesin proteins
US6394952B1 (en) 1998-02-03 2002-05-28 Adeza Biomedical Corporation Point of care diagnostic systems
US6267722B1 (en) 1998-02-03 2001-07-31 Adeza Biomedical Corporation Point of care diagnostic systems
US6596501B2 (en) 1998-02-23 2003-07-22 Fred Hutchinson Cancer Research Center Method of diagnosing autoimmune disease
CN1249226C (zh) 1998-03-04 2006-04-05 金克克国际有限公司 支链淀粉酶的修饰形式
US6284194B1 (en) 1998-03-11 2001-09-04 Albert E. Chu Analytical assay device and methods using surfactant treated membranes to increase assay sensitivity
AU768018C (en) 1998-03-20 2004-09-30 Curators Of The University Of Missouri, The Early pregnancy diagnosis using PAGS (pregnancy- associated glycoproteins)
EP1696236B1 (en) * 1998-03-30 2014-07-16 OraSure Technologies, Inc. Collection device for assay of oral fluids
US8062908B2 (en) * 1999-03-29 2011-11-22 Orasure Technologies, Inc. Device for collection and assay of oral fluids
US6303081B1 (en) * 1998-03-30 2001-10-16 Orasure Technologies, Inc. Device for collection and assay of oral fluids
US6337200B1 (en) * 1998-03-31 2002-01-08 Geron Corporation Human telomerase catalytic subunit variants
CA2735260A1 (en) * 1998-03-31 1999-10-07 Esoterix Genetic Laboratories, Llc Methods for the diagnosis and treatment of lung cancer by detection of proto-oncogene overexpression
US6274314B1 (en) 1998-04-02 2001-08-14 Nyxis Neurotherapies, Inc. Diagnostic assay for the modified nucleosides pseudouridine, 7-methyladenosine, or 1-methyladenosine
US7108968B2 (en) * 1998-04-03 2006-09-19 Affymetrix, Inc. Mycobacterial rpoB sequences
EP1071943A4 (en) 1998-04-14 2005-08-10 Univ California DETECTION ASSAYS FOR DEPOLYMERIZATION INHIBITORS OF MICROTUBLES
US6699969B1 (en) 1998-04-14 2004-03-02 The Regents Of The University Of California Assays for the detection of microtubule depolymerization inhibitors
US6872537B1 (en) 1998-04-14 2005-03-29 Regents Of The University Of California Assays for the detection of microtubule depolymerization inhibitors
US6348573B1 (en) 1998-04-27 2002-02-19 The Regents Of The University Of Michigan Compositions and methods for identifying apoptosis signaling pathway inhibitors and activators
US6271044B1 (en) 1998-05-06 2001-08-07 University Of Pittsburgh Of The Commonwealth System Of Higher Education Method and kit for detecting an analyte
WO2000005396A1 (en) 1998-07-21 2000-02-03 Danisco A/S Foodstuff
HUP0103577A2 (hu) * 1998-07-21 2002-01-28 Burstein Technologies, Inc. Optikai lemez alapú eszközök és eljárások
US7402400B2 (en) 2001-07-03 2008-07-22 Regents Of The University Of California Mammalian sweet taste receptors
EP1806362B1 (en) 1998-07-28 2010-07-21 The Regents of the University of California Nucleic acids encoding a G-protein coupled receptor involved in sensory transduction
US7640083B2 (en) 2002-11-22 2009-12-29 Monroe David A Record and playback system for aircraft
SE9803099D0 (sv) 1998-09-13 1998-09-13 Karolinska Innovations Ab Nucleic acid transfer
EP2314696A1 (en) 1998-09-21 2011-04-27 Schering Corporation Therapeutic uses of human Interleukin-B50 antagonist.
EP0997476A3 (en) 1998-09-25 2000-07-19 Schering-Plough Antibodies to a mammalian Langerhans cell antigen and their uses
US7071324B2 (en) * 1998-10-13 2006-07-04 Brown University Research Foundation Systems and methods for sequencing by hybridization
JP3622532B2 (ja) * 1998-10-13 2005-02-23 松下電器産業株式会社 酵素免疫分析用試薬及びそれを用いた分析方法
EP1123401A1 (en) 1998-10-22 2001-08-16 The General Hospital Corporation BIOACTIVE PEPTIDES AND PEPTIDE DERIVATIVES OF PARATHYROID HORMONE (PTH) AND PARATHYROID HORMONE-RELATED PEPTIDE (PTHrP)
US7297554B2 (en) * 1998-11-18 2007-11-20 Microdiagnostics, Inc. Immunoassay system
US6638760B1 (en) 1998-11-25 2003-10-28 Pe Corporation (Ny) Method and apparatus for flow-through hybridization
ES2333694T3 (es) 1999-01-11 2010-02-26 Schering Corporation Citoquinas de mamiferos relacionados con la interleuquina-17.polinucleotido que las codifican y sus instalaciones.
CA2360044A1 (en) * 1999-01-15 2000-07-20 Medtox Scientific, Inc. Lateral flow test strip
US6156515A (en) * 1999-02-09 2000-12-05 Urocor, Inc. Prostate-specific gene for diagnosis, prognosis and management of prostate cancer
EP1159299B1 (en) 1999-03-11 2009-01-14 Schering Corporation Mammalian cytokines; related reagents and methods
US6566500B1 (en) 1999-03-30 2003-05-20 Board Of Regents, The University Of Texas System Compositions and methods for modifying toxic effects of proteinaceous compounds
KR20110102476A (ko) 1999-05-13 2011-09-16 메디칼 리서취 카운실 Ｏｘ2 수용체 동족체
WO2000069898A2 (en) 1999-05-14 2000-11-23 Arbor Vita Corporation Molecular interactions in allergy cells
PT1181366E (pt) 1999-06-01 2009-05-25 Schering Corp Proteínas receptoras de mamífero; reagentes e métodos relacionados
GB9914210D0 (en) 1999-06-17 1999-08-18 Danisco Promoter
HK1042517B (en) 1999-07-30 2009-12-24 Merck Sharp & Dohme Corp. Mammalian cytokines; related reagents
EP1905832A3 (en) 1999-09-09 2009-09-09 Schering Corporation Mammalian interleukin-12 P40 and interleukin B30, combinations thereof, antibodies, uses in pharmaceutical compositions
WO2001023521A2 (en) * 1999-09-29 2001-04-05 The General Hospital Corporation Polypeptide derivatives of parathyroid hormone (pth)
US6306665B1 (en) 1999-10-13 2001-10-23 A-Fem Medical Corporation Covalent bonding of molecules to an activated solid phase material
US7332275B2 (en) 1999-10-13 2008-02-19 Sequenom, Inc. Methods for detecting methylated nucleotides
EP1226166B1 (en) 1999-10-18 2010-01-27 Prince Henry's Institute of Medical Research Immuno-interactive fragments of the alpha c subunit of inhibin
US7030228B1 (en) 1999-11-15 2006-04-18 Miltenyi Biotec Gmbh Antigen-binding fragments specific for dendritic cells, compositions and methods of use thereof antigens recognized thereby and cells obtained thereby
AU1488501A (en) 1999-11-24 2001-06-04 Schering Corporation Methods of inhibiting metastasis
US6458326B1 (en) 1999-11-24 2002-10-01 Home Diagnostics, Inc. Protective test strip platform
DK1247095T3 (da) 1999-12-06 2008-12-08 Univ Illinois TCR-proteiner med höj affinitet samt fremgangsmåder
FR2802214B1 (fr) * 1999-12-09 2005-07-22 Biomerieux Sa Nouveaux substrats chromogenes a base d'alizarine, leurs utilisations et compositions contenant de tels substrats
US6544792B1 (en) 1999-12-21 2003-04-08 Genencor International, Inc. Production of secreted polypeptides
MXPA02007184A (es) 2000-01-25 2004-02-26 Univ Queensland Proteinas que comprenden regiones conservadas de antigenos de superficie nhha de neisseria meningitidis.
US20010051348A1 (en) * 2000-01-28 2001-12-13 Lee Chee Wee Novel ligands and methods for preparing same
DE10003734A1 (de) * 2000-01-28 2001-08-02 Bosch Gmbh Robert Detektionsverfahren und -vorrichtung
KR20020086508A (ko) 2000-02-08 2002-11-18 상가모 바이오사이언스 인코포레이티드 약물 발견용 세포
EP1172653A4 (en) * 2000-02-18 2003-07-16 Matsushita Electric Industrial Co Ltd MONITORING CHIP FOR DEVICE FOR MEASURING SENSORS
TW201006846A (en) 2000-03-07 2010-02-16 Senomyx Inc T1R taste receptor and genes encidung same
WO2001066568A2 (en) * 2000-03-09 2001-09-13 Heska Corporation Use of recombinant antigens to determine the immune status of an animal
US7875442B2 (en) * 2000-03-24 2011-01-25 Eppendorf Array Technologies Identification and quantification of a plurality of biological (micro)organisms or their components
US8288128B2 (en) * 2004-11-18 2012-10-16 Eppendorf Array Technologies S.A. Real-time quantification of multiple targets on a micro-array
US7829313B2 (en) * 2000-03-24 2010-11-09 Eppendorf Array Technologies Identification and quantification of a plurality of biological (micro)organisms or their components
US20030108927A1 (en) * 2000-04-03 2003-06-12 Kathryn Leishman Compositions and methods for the prevention, treatment and detection of tuberculosis and other diseases
US6699722B2 (en) 2000-04-14 2004-03-02 A-Fem Medical Corporation Positive detection lateral-flow apparatus and method for small and large analytes
AU2001251655A1 (en) 2000-04-18 2001-10-30 Schering Corporation Cytokine uses; compositions; methods
AU2001261103B2 (en) 2000-04-29 2007-08-23 University Of Iowa Research Foundation Diagnostics and therapeutics for macular degeneration-related disorders
US7422743B2 (en) 2000-05-10 2008-09-09 Schering Corporation Mammalian receptor protein DCRS5;methods of treatment
SK287984B6 (sk) 2000-05-10 2012-08-06 Schering Corporation Substantially pure or recombinant polypeptide, nucleic acid, host cell, method for the preparation of polypeptide, binding compound, kit, composition comprising an antibody and use thereof
AUPQ755300A0 (en) 2000-05-17 2000-06-08 Monash University Immune potentiating compositions
AU6488901A (en) 2000-05-25 2001-12-03 Schering Corp Human receptor proteins; related reagents and methods
WO2005000087A2 (en) * 2003-06-03 2005-01-06 Chiron Corporation Gene products differentially expressed in cancerous colon cells and their methods of use ii
US6528321B1 (en) 2000-06-26 2003-03-04 Beckman Coulter, Inc. Opposable-element chromatographic assay device for detection of analytes in whole blood samples
US6673614B2 (en) 2000-06-27 2004-01-06 Cell Genesys, Inc. Rapid methods and kits for detection and semi-quantitation of anti-adenovirus antibody
US6958214B2 (en) 2000-07-10 2005-10-25 Sequenom, Inc. Polymorphic kinase anchor proteins and nucleic acids encoding the same
GB0020498D0 (en) 2000-08-18 2000-10-11 Sterix Ltd Compound
US6372516B1 (en) 2000-09-07 2002-04-16 Sun Biomedical Laboratories, Inc. Lateral flow test device
WO2002020722A2 (en) 2000-09-08 2002-03-14 Board Of Regents, The University Of Texas Syste Methods and compositions for in vitro targeting
CN1452633A (zh) 2000-09-08 2003-10-29 先灵公司 哺乳动物基因、相关试剂及方法
US6673623B1 (en) 2000-09-12 2004-01-06 Novocure, Inc. Methods and compositions that control lipid production
DE60115958T2 (de) * 2000-09-18 2006-08-03 Genencor International, Inc., Palo Alto Zwillingsarginin translokation in bacillus
US7186521B2 (en) * 2000-09-25 2007-03-06 The Regents Of The University Of California Determining the effect of a substance on sequestration, uptake, and accumulation of amyloid in brain cells
US7052831B2 (en) * 2000-09-29 2006-05-30 Becton Dickinson And Company Detection of multiple analytes from a single sample using a multi-well, multi-analyte flow-through diagnostic test device
US7045283B2 (en) 2000-10-18 2006-05-16 The Regents Of The University Of California Methods of high-throughput screening for internalizing antibodies
US6890734B2 (en) 2000-11-10 2005-05-10 Schering Corporation Nucleic acids encoding a cytokine receptor complex
USD468437S1 (en) 2000-11-21 2003-01-07 Acon Laboratories, Inc. Test platform
WO2002044366A2 (en) * 2000-11-29 2002-06-06 Lynkeus Biotech Gmbh Retina-specific human proteins c70rf9, c120rf7, mpp4 and f379
US20020165149A1 (en) * 2000-12-08 2002-11-07 Kranz David M. Mutated class II major histocompatibility proteins
TW201022287A (en) 2001-01-03 2010-06-16 Senomyx Inc T1R taste receptors and genes encoding same
GB0101762D0 (en) * 2001-01-23 2001-03-07 Medical Res Council Method
US7087389B2 (en) * 2001-02-09 2006-08-08 Council Of Scientific & Industrial Research Highly cost-effective analytical device for performing immunoassays with ultra high sensitivity
US20020168663A1 (en) * 2001-02-27 2002-11-14 Phan Brigitte Chau Methods for DNA conjugation onto solid phase including related optical biodiscs and disc drive systems
US6525330B2 (en) 2001-02-28 2003-02-25 Home Diagnostics, Inc. Method of strip insertion detection
US6562625B2 (en) 2001-02-28 2003-05-13 Home Diagnostics, Inc. Distinguishing test types through spectral analysis
US6541266B2 (en) 2001-02-28 2003-04-01 Home Diagnostics, Inc. Method for determining concentration of an analyte in a test strip
WO2002072779A2 (en) * 2001-03-12 2002-09-19 Affymetrix, Inc. Nucleic acid labeling compounds
US20030104410A1 (en) * 2001-03-16 2003-06-05 Affymetrix, Inc. Human microarray
US20030228639A1 (en) * 2001-03-19 2003-12-11 Wright George L Prostate cancer markers
US20030220475A1 (en) * 2001-04-03 2003-11-27 Fields Howard A. Neutralizing immunogenic hev polypepetides
US7618789B2 (en) * 2001-04-06 2009-11-17 The United States Of America As Represented By The Secretary Of Department Of Health And Human Services Use of semenogelin in the diagnosis, prognosis and treatment of cancer
US7867756B2 (en) * 2001-04-12 2011-01-11 Arkray, Inc. Specimen analyzing implement
US6916626B1 (en) * 2001-04-25 2005-07-12 Rockeby Biomed Ltd. Detection of Candida
CN100591212C (zh) 2001-05-18 2010-02-24 丹尼斯科有限公司 改善生面团和面包质量的方法
WO2002094985A2 (en) 2001-05-22 2002-11-28 Merck & Co., Inc. Beta-secretase substrates and uses thereof
AU2002312410A1 (en) * 2001-06-08 2002-12-23 Target Protein Technologies, Inc. Tissue-specific endothelial membrane proteins
US20070190534A1 (en) * 2001-06-11 2007-08-16 Genesis Genomics Inc. Mitochondrial sites and genes associated with prostate cancer
EP1412750B1 (en) 2001-06-26 2012-05-23 Senomyx, Inc. T1r2-t1r3 hetero-oligomeric sweet taste receptors and cell lines that express said receptors and use thereof for identification of sweet taste compounds
US7141416B2 (en) * 2001-07-12 2006-11-28 Burstein Technologies, Inc. Multi-purpose optical analysis optical bio-disc for conducting assays and various reporting agents for use therewith
EP1439854B1 (en) * 2001-07-23 2016-12-14 The General Hospital Corporation Conformationally constrained parathyroid hormone (pth) analogs
US7300633B2 (en) 2001-07-25 2007-11-27 Oakville Hong Kong Company Limited Specimen collection container
JP4265149B2 (ja) * 2001-07-25 2009-05-20 セイコーエプソン株式会社 電気光学装置、電気光学装置の製造方法
US7270959B2 (en) 2001-07-25 2007-09-18 Oakville Hong Kong Company Limited Specimen collection container
US6833441B2 (en) * 2001-08-01 2004-12-21 Abmaxis, Inc. Compositions and methods for generating chimeric heteromultimers
JP2004536614A (ja) * 2001-08-01 2004-12-09 ユニバーシティ オブ ユタ Ｐｄｅ３環状ヌクレオチド・ホスホジエステラーゼのアイソフォーム選択的な阻害剤および活性化剤
US20030082596A1 (en) * 2001-08-08 2003-05-01 Michael Mittmann Methods of genetic analysis of probes: test3
US6855561B2 (en) 2001-09-10 2005-02-15 Quidel Corporation Method for adding an apparent non-signal line to a lateral flow assay
WO2003024993A2 (en) 2001-09-20 2003-03-27 Board Of Regents, The University Of Texas System Measuring circulating therapeutic antibody, antigen and antigen/antibody complexes using elisa assays
US7108975B2 (en) * 2001-09-21 2006-09-19 Regents Of The University Of Michigan Atlastin
US7582425B2 (en) * 2001-09-21 2009-09-01 The Regents Of The University Of Michigan Atlastin
CA2461844C (en) 2001-09-27 2011-04-05 Pioneer Hi-Bred International, Inc. Phytate polynucleotides and methods of use
AU2002330102A1 (en) * 2001-09-28 2003-04-14 Aspenbio, Inc. Bovine pregnancy test
EP1439857B1 (en) 2001-10-12 2009-02-25 Schering Corporation USE OF BISPECIFIC ANTIBODIES BINDING TO THE ACTIVATING RECEPTOR FcEpsilonRI AND TO THE INHIBITING RECEPTOR OX2Ra (CD200Ra) TO REGULATE IMMUNE RESPONSES
US7537731B2 (en) * 2001-10-19 2009-05-26 Panasonic Corporation Specific binding analysis device
US7175983B2 (en) * 2001-11-02 2007-02-13 Abmaxis, Inc. Adapter-directed display systems
AU2002366097B2 (en) 2001-11-20 2008-09-18 Monsanto Technology Llc Compositions and methods for accurate early pregnancy diagnosis
US6952704B2 (en) * 2001-11-26 2005-10-04 Microsoft Corporation Extending a directory schema independent of schema modification
US20030099621A1 (en) 2001-11-29 2003-05-29 Robert Chow Stem cell screening and transplantation therapy for HIV infection
US20050036943A1 (en) * 2001-12-07 2005-02-17 Broughton Kenneth Shane Methods and compositions for the diagnosis of asthma
CN100510747C (zh) * 2001-12-12 2009-07-08 普罗托姆系统有限公司 诊断试验方法
US7244393B2 (en) 2001-12-21 2007-07-17 Kimberly-Clark Worldwide, Inc. Diagnostic device and system
US6837171B1 (en) 2002-04-29 2005-01-04 Palmer/Snyder Furniture Company Lightweight table with unitized table top
US20030119203A1 (en) 2001-12-24 2003-06-26 Kimberly-Clark Worldwide, Inc. Lateral flow assay devices and methods for conducting assays
US8367013B2 (en) 2001-12-24 2013-02-05 Kimberly-Clark Worldwide, Inc. Reading device, method, and system for conducting lateral flow assays
US20050003459A1 (en) * 2002-01-30 2005-01-06 Krutzik Siegfried Richard Multi-purpose optical analysis disc for conducting assays and related methods for attaching capture agents
US7255986B2 (en) * 2002-01-31 2007-08-14 The Board Of Trustees Operating Michigan State University Compositions for the diagnosis and treatment of epizootic catarrhal enteritis in ferrets
US20030186875A1 (en) 2002-02-01 2003-10-02 Rene De Waal Malefyt Uses of mammalian cytokine; related reagents
US7094579B2 (en) 2002-02-13 2006-08-22 Xoma Technology Ltd. Eukaryotic signal sequences for prokaryotic expression
CA2477035A1 (en) * 2002-02-21 2003-09-04 Eastern Virginia Medical School Protein biomarkers that distinguish prostate cancer from non-malignant cells
AU2003225589A1 (en) 2002-02-22 2003-09-09 The Government Of The United States Of America, As Represented By The Secretary, Dept. Of Health And Brother of the regulator of imprinted sites (boris)
US7053188B2 (en) 2002-02-22 2006-05-30 Purdue Research Foundation Monoclonal antibodies specific for neoplasia-specific NADH:disulfide reductase
US6703216B2 (en) 2002-03-14 2004-03-09 The Regents Of The University Of California Methods, compositions and apparatuses for detection of gamma-hydroxybutyric acid (GHB)
US7332585B2 (en) 2002-04-05 2008-02-19 The Regents Of The California University Bispecific single chain Fv antibody molecules and methods of use thereof
JP2004003976A (ja) * 2002-04-05 2004-01-08 Matsushita Electric Ind Co Ltd 特異結合分析方法およびこれに用いるデバイス
CA2391438A1 (en) * 2002-05-01 2003-11-01 Procyon Biopharma Inc. Psp94 diagnostic reagents and assays
US7534580B2 (en) * 2002-05-01 2009-05-19 Ambrilia Biopharma Inc. PSP94 diagnostic reagents and assays
AU2003243199B2 (en) * 2002-05-02 2008-08-21 Aspenbio Pharma, Inc Pregnancy detection
CA2484676A1 (en) * 2002-05-03 2003-11-13 Sequenom, Inc. Kinase anchor protein muteins, peptides thereof, and related methods
WO2003102595A1 (en) * 2002-05-31 2003-12-11 Genetype Pty Ltd Maternal antibodies as fetal cell markers to identify and enrich fetal cells from maternal blood
CN1678734B (zh) 2002-06-27 2012-12-12 韦尔瓦制药有限公司 分化调节试剂及其应用
US7504215B2 (en) 2002-07-12 2009-03-17 Affymetrix, Inc. Nucleic acid labeling methods
AU2003304195B8 (en) 2002-07-15 2008-08-28 Board Of Regents, The University Of Texas System Combinatorial protein library screening by periplasmic expression
WO2004006847A2 (en) 2002-07-15 2004-01-22 Board Of Regents, The University Of Texas System Selected antibodies and duramycin peptides binding to anionic phospholipids and aminophospholipids and their use in treating viral infections and cancer
US7794716B2 (en) 2002-07-25 2010-09-14 Glenveigh Pharmaceuticals, Llc Antibody composition and passive immunization against pregnancy-induced hypertension
CA2493782C (en) 2002-07-26 2016-05-31 The Walter And Eliza Hall Institute Of Medical Research Immunogenic compositions and diagnostic and therapeutic uses thereof
ATE541047T1 (de) 2002-08-01 2012-01-15 Univ California Therapeutische monoklonale antikörper zur neutralisierung von botulinum neurotoxinen
WO2004014311A2 (en) * 2002-08-10 2004-02-19 Yale University Nogo receptor antagonists
CN1697972B (zh) 2002-08-13 2010-09-29 N-Dia公司 检测阴道分泌物中羊水的装置和方法
DK2221620T3 (da) 2002-08-23 2014-01-06 Bayer Pharma AG Polypeptidbiomarkører til diagnosticering af Alzheimers sygdom
US7432105B2 (en) 2002-08-27 2008-10-07 Kimberly-Clark Worldwide, Inc. Self-calibration system for a magnetic binding assay
US7285424B2 (en) 2002-08-27 2007-10-23 Kimberly-Clark Worldwide, Inc. Membrane-based assay devices
US7314763B2 (en) 2002-08-27 2008-01-01 Kimberly-Clark Worldwide, Inc. Fluidics-based assay devices
DE60325382D1 (de) 2002-09-09 2009-01-29 Arbor Vita Corp Verfahren zur diagnose von gebärmutterhalskrebs
US6774758B2 (en) * 2002-09-11 2004-08-10 Kalyan P. Gokhale Low harmonic rectifier circuit
US20050042621A1 (en) * 2002-09-27 2005-02-24 Affymetrix, Inc. Method for preparing a nucleic acid sample for hybridization to an array
ES2525318T3 (es) * 2002-10-11 2014-12-22 Zbx Corporation Dispositivos de diagnóstico
BR0315605A (pt) 2002-10-24 2005-08-30 Sterix Ltd Inibidores da 11-beta-hidroxi esteróide desidrogenase tipo 1 e tipo 2
AU2003295448A1 (en) * 2002-11-12 2004-07-14 Strategic Diagnostics Inc. Isolation and confirmation of analytes from test devices
US7250289B2 (en) * 2002-11-20 2007-07-31 Affymetrix, Inc. Methods of genetic analysis of mouse
US7314750B2 (en) * 2002-11-20 2008-01-01 Affymetrix, Inc. Addressable oligonucleotide array of the rat genome
JP2006508662A (ja) 2002-12-04 2006-03-16 アプレラ コーポレイション ポリヌクレオチドの多重増幅
US7247500B2 (en) 2002-12-19 2007-07-24 Kimberly-Clark Worldwide, Inc. Reduction of the hook effect in membrane-based assay devices
US20040121334A1 (en) 2002-12-19 2004-06-24 Kimberly-Clark Worldwide, Inc. Self-calibrated flow-through assay devices
AU2003293562A1 (en) * 2002-12-26 2004-07-22 Meso Scale Technologies, Llc Methods, compositions and kits for biomarker extraction
AU2003285724A1 (en) * 2002-12-31 2004-07-22 Pharmacia & Upjohn Company Llc Canine l-pbe sequences
JP2006512075A (ja) * 2002-12-31 2006-04-13 ファルマシア・アンド・アップジョン・カンパニー・エルエルシー イヌｃｙｐ１ａ２配列
JP2006518989A (ja) * 2002-12-31 2006-08-24 ファルマシア・アンド・アップジョン・カンパニー・エルエルシー イヌのダイオキシン／アリール炭化水素受容体配列
US7560272B2 (en) 2003-01-04 2009-07-14 Inverness Medical Switzerland Gmbh Specimen collection and assay container
US7955814B2 (en) 2003-01-17 2011-06-07 Danisco A/S Method
MXPA05007654A (es) 2003-01-17 2005-09-30 Danisco Metodo.
ATE533849T1 (de) 2003-01-17 2011-12-15 Danisco Verfahren zur in-situ-herstellung eines emulgators in einem nahrungsmittel
US20050196766A1 (en) 2003-12-24 2005-09-08 Soe Jorn B. Proteins
US20100143442A1 (en) 2003-02-05 2010-06-10 Queensland University Of Technology Growth factor complexes and modulation of cell migration and growth
AU2003900481A0 (en) 2003-02-05 2003-02-20 Queensland University Of Technology Synthetic modulators of cell migration and growth
EP1594900A2 (en) * 2003-02-14 2005-11-16 Salmedix, Inc. Compositions and methods for the detection and treatment of methylthioadenosine phosphorylase deficient cancers
WO2004073492A2 (en) * 2003-02-14 2004-09-02 Massachusetts Eye And Ear Infirmary Chlamydia pneumoniae associated chronic intraocular disorders and treatment thereof
EP1599608A4 (en) * 2003-03-05 2007-07-18 Genetic Technologies Ltd Identification of fetal DNA and fetal cell marker in maternal plasma or serum
ES2360291T3 (es) 2003-03-07 2011-06-02 New England Medical Center Hospitals, Inc. TRATAMIENTO DE ENFERMEDADES POR DEPOSICIÓN DE IgA1.
EP1610813A4 (en) * 2003-03-19 2009-07-01 Gen Hospital Corp CONFORMATION RESTRICTED PARATHORMONE WITH A HELIX STABILIZERS
AU2003901325A0 (en) * 2003-03-21 2003-04-03 Stephen Locarnini Therapeutic, prophylactic and diagnostic agents
US20070043512A1 (en) * 2003-03-26 2007-02-22 Michael Rolph Therapeutic and prophylactic compositions and uses therefor
US20040197819A1 (en) 2003-04-03 2004-10-07 Kimberly-Clark Worldwide, Inc. Assay devices that utilize hollow particles
US7851209B2 (en) 2003-04-03 2010-12-14 Kimberly-Clark Worldwide, Inc. Reduction of the hook effect in assay devices
ATE517926T1 (de) 2003-04-04 2011-08-15 Yeda Res & Dev Antikörper zur hemmung der aktivität von mmp-2 und mmp-9
MXPA05011100A (es) * 2003-04-16 2006-04-18 Univ Yale Antagonistas de receptor nogo para el tratamiento de condiciones que comprenden placas amiloideas.
US7321065B2 (en) * 2003-04-18 2008-01-22 The Regents Of The University Of California Thyronamine derivatives and analogs and methods of use thereof
ES2335011T3 (es) * 2003-05-27 2010-03-18 Mitsubishi Kagaku Iatron, Inc. Procedimiento inmunocromatografico.
US20060246526A1 (en) * 2003-06-02 2006-11-02 Gyros Patent Ab Microfluidic affinity assays with improved performance
AU2004247146A1 (en) * 2003-06-12 2004-12-23 Vaxgen, Inc. HIV-1 envelope glycoproteins having unusual disulfide structure
US7910544B2 (en) 2003-07-17 2011-03-22 The General Hospital Corporation Conformationally constrained parthyroid hormone (PTH) analogs
US20050014734A1 (en) * 2003-07-18 2005-01-20 Genovate Biotechnology Co., Ltd. Modulation of interleukin-10 by DHEA
SG153714A1 (en) 2003-08-06 2009-07-29 Senomyx Inc T1r hetero-oligomeric taste receptors, cell lines that express said receptors, and taste compounds
WO2005014795A2 (en) 2003-08-08 2005-02-17 Genenews Inc. Osteoarthritis biomarkers and uses thereof
US20050064479A1 (en) * 2003-08-12 2005-03-24 Affymetrix, Inc. Compounds and methods for post incorporation labeling of nucleic acids
JP2007502118A (ja) 2003-08-14 2007-02-08 エクセリクシス， インク． βカテニン経路のモディファイヤーとしてのＳＵＬＦｓ及び使用方法
US7517495B2 (en) 2003-08-25 2009-04-14 Inverness Medical Switzerland Gmbh Biological specimen collection and analysis system
ATE491953T1 (de) 2003-09-15 2011-01-15 Oklahoma Med Res Found Verfahren zur verwendung von cytokintests zur diagnose, behandlung und beurteilung von ankyloider spondylitis
SG146622A1 (en) 2003-09-18 2008-10-30 Genmab As Differentially expressed tumour-specific polypeptides for use in the diagnosis and treatment of cancer
JP4933258B2 (ja) 2003-09-22 2012-05-16 クイデル コーポレーション 試料中の複数分析物の検出装置
US20050064435A1 (en) * 2003-09-24 2005-03-24 Xing Su Programmable molecular barcodes
US20050079484A1 (en) * 2003-10-10 2005-04-14 Heineman William Richard Method of detecting biological materials in liquid
US7901880B2 (en) 2003-10-21 2011-03-08 Orion Genomics Llc Differential enzymatic fragmentation
US20050227251A1 (en) 2003-10-23 2005-10-13 Robert Darnell Method of purifying RNA binding protein-RNA complexes
PE20050925A1 (es) 2003-11-10 2005-11-29 Schering Corp Anticuerpo recombinante humanizado anti-interleuquina 10
US7943395B2 (en) 2003-11-21 2011-05-17 Kimberly-Clark Worldwide, Inc. Extension of the dynamic detection range of assay devices
US20050112703A1 (en) 2003-11-21 2005-05-26 Kimberly-Clark Worldwide, Inc. Membrane-based lateral flow assay devices that utilize phosphorescent detection
US7713748B2 (en) 2003-11-21 2010-05-11 Kimberly-Clark Worldwide, Inc. Method of reducing the sensitivity of assay devices
JP4813364B2 (ja) 2003-11-25 2011-11-09 アメリカ合衆国 突然変異型抗ｃｄ２２抗体および免疫複合体
US7943089B2 (en) 2003-12-19 2011-05-17 Kimberly-Clark Worldwide, Inc. Laminated assay devices
US7863053B2 (en) * 2003-12-23 2011-01-04 Kimberly-Clark Worldwide, Inc. Swab-based diagnostic systems
US7098040B2 (en) * 2003-12-23 2006-08-29 Kimberly-Clark Worldwide, Inc. Self-contained swab-based diagnostic systems
US7399467B2 (en) 2003-12-23 2008-07-15 Arbor Vita Corporation Antibodies for oncogenic strains of HPV and methods of their use
GB0716126D0 (en) * 2007-08-17 2007-09-26 Danisco Process
BRPI0417533B1 (pt) 2003-12-24 2016-03-01 Danisco enzima variante glicolipídio aciltransferase, uso e método para sua produção, método para o preparo de um produto alimentício e produto assado de farinha, processo de refinamento enzimático
US7718408B2 (en) * 2003-12-24 2010-05-18 Danisco A/S Method
WO2008090395A1 (en) 2007-01-25 2008-07-31 Danisco A/S Production of a lipid acyltransferase from transformed bacillus licheniformis cells
US7150995B2 (en) 2004-01-16 2006-12-19 Metrika, Inc. Methods and systems for point of care bodily fluid analysis
US20050186646A1 (en) * 2004-01-26 2005-08-25 Cruz Miguel A. Rapid assay to detect ADAMTS-13 activity
EP2816351A3 (en) * 2004-01-27 2015-03-25 Compugen Ltd. Methods and systems for annotating biomolecular sequences
US7638093B2 (en) * 2004-01-28 2009-12-29 Dnt Scientific Research, Llc Interrupted flow rapid confirmatory immunological testing device and method
WO2005075998A1 (en) * 2004-01-29 2005-08-18 Dsm Ip Assets B.V. Improved lateral flow binding assay
CA2555208A1 (en) * 2004-02-18 2005-09-01 Merck & Co., Inc. Nucleic acid molecules encoding novel murine low-voltage activated calcium channel proteins, designated-alpha 1h, encoded proteins and methods of use thereof
GB0403864D0 (en) 2004-02-20 2004-03-24 Ucl Ventures Modulator
EP2208797A3 (en) 2004-03-01 2010-11-24 Applied Biosystems, LLC Methods, compositions and kits for use in polynucleotide amplification
DK2712617T3 (en) 2004-03-12 2017-02-13 Intercept Pharmaceuticals Inc Treatment of fibrosis with Fxr ligands.
GB0405637D0 (en) 2004-03-12 2004-04-21 Danisco Protein
JP2007530946A (ja) * 2004-03-23 2007-11-01 クイデル コーポレイション ハイブリッド相ラテラルフロー・アッセイ
US7396654B2 (en) 2004-04-15 2008-07-08 University Of Florida Research Foundation, Inc. Neural proteins as biomarkers for traumatic brain injury
EA013071B1 (ru) 2004-04-23 2010-02-26 ФАРМАЦИЯ ЭНД АПДЖОН КОМПАНИ ЭлЭлСи Способ получения вируса репродуктивно-респираторного синдрома свиней (pprsv) и способ получения pprsv вакцины
US7796266B2 (en) 2004-04-30 2010-09-14 Kimberly-Clark Worldwide, Inc. Optical detection system using electromagnetic radiation to detect presence or quantity of analyte
US7815854B2 (en) 2004-04-30 2010-10-19 Kimberly-Clark Worldwide, Inc. Electroluminescent illumination source for optical detection systems
US7939251B2 (en) 2004-05-06 2011-05-10 Roche Molecular Systems, Inc. SENP1 as a marker for cancer
EP2400030B1 (en) 2004-05-18 2016-01-20 The Board of Trustees of the Leland Stanford Junior University Detection of protein translocation by beta-galactosidase reporter fragment complementation
AU2005250370B2 (en) 2004-05-28 2010-04-01 Agensys, Inc. Antibodies and related molecules that bind to PSCA proteins
EP2527447A1 (en) 2004-06-03 2012-11-28 Athlomics Pty Ltd Agents and methods for diagnosing stress
US7776583B2 (en) * 2004-06-03 2010-08-17 Meso Scale Technologies, Llc Methods and apparatuses for conducting assays
EP2453024B1 (en) 2004-06-21 2017-12-06 The Board of Trustees of The Leland Stanford Junior University Genes and pathways differentially expressed in bipolar disorder and/or major depressive disorder
US8034553B2 (en) 2004-06-24 2011-10-11 Kimberly-Clark Worldwide, Inc. Biomarkers for wound healing
US7521226B2 (en) 2004-06-30 2009-04-21 Kimberly-Clark Worldwide, Inc. One-step enzymatic and amine detection technique
US7763454B2 (en) 2004-07-09 2010-07-27 Church & Dwight Co., Inc. Electronic analyte assaying device
WO2006008508A1 (en) 2004-07-16 2006-01-26 Danisco A/S Enzymatic oil-degumming method
US20090226552A1 (en) * 2004-07-22 2009-09-10 Colorado State University Research Foundation Agents and methods for diagnosing osteoarthritis
EP1789437A4 (en) * 2004-07-30 2008-11-05 Sinai School Medicine INHIBITORS OF NPC1L1 AND NPC1L1 AND METHODS OF USE THEREOF
US7510858B2 (en) * 2004-08-02 2009-03-31 Janssen Pharmaceutica N.V. IRAK 1c splice variant and its use
US20060073168A1 (en) * 2004-08-11 2006-04-06 Stephens David S Neisseria meningitidis serogroup a capsular polysaccharide acetyltransferase, methods and compositions
WO2006023312A2 (en) * 2004-08-20 2006-03-02 Carl Deirmengian Diagnostic assay for source of inflammation
US7893197B2 (en) * 2004-08-25 2011-02-22 Janssen Pharmaceutica N.V. Relaxin-3 chimeric polypeptides and their preparation and use
MX2007002294A (es) 2004-08-26 2007-10-19 Engeneic Molecular Delivery Pty Ltd Suministro de acidos nucleicos funcionales a celulas mamiferas via minicelulas intactas, derivadas bacterialmente.
AU2005284822B2 (en) 2004-09-14 2011-03-24 Regents Of The University Of Colorado Method for treatment with bucindolol based on genetic targeting
JP5085326B2 (ja) 2004-09-18 2012-11-28 ユニバーシティ オブ メリーランド，ボルチモア ＮＣＣａ−ＡＴＰチャネルを標的とする処置剤およびその使用方法
JP5307397B2 (ja) 2004-09-18 2013-10-02 ユニバーシティ オブ メリーランド，ボルチモア ＮＣＣａ−ＡＴＰチャネルを標的とする治療剤およびその使用方法
US8685711B2 (en) 2004-09-28 2014-04-01 Singulex, Inc. Methods and compositions for highly sensitive detection of molecules
US9040305B2 (en) 2004-09-28 2015-05-26 Singulex, Inc. Method of analysis for determining a specific protein in blood samples using fluorescence spectrometry
GB0422052D0 (en) 2004-10-04 2004-11-03 Dansico As Enzymes
US7390489B2 (en) 2004-10-08 2008-06-24 Komed Co., Ltd. Monoclonal antibody selectively recognizing listeria monocytogenes, hybridoma producing the antibody, test kit comprising the antibody and detection method of listeria monocytogenes using the antibody
GB0423139D0 (en) 2004-10-18 2004-11-17 Danisco Enzymes
WO2006047417A2 (en) 2004-10-21 2006-05-04 University Of Florida Research Foundation, Inc. Detection of cannabinoid receptor biomarkers and uses thereof
JP5948627B2 (ja) 2004-10-29 2016-07-20 レイショファーム ゲーエムベーハー 線維芽細胞成長因子（ｆｇｆ）のリモデリングと糖質ペグ化
AU2005302291B2 (en) * 2004-11-02 2011-02-10 The Government Of The United States Of America As Represented By The Secretary Department Of Health & Human Services Compositions and methods for treating hyperproliferative disorders
ATE520029T1 (de) * 2004-11-05 2011-08-15 Hoffmann La Roche Biochemisches gerät und nachweisverfahren
GB0424940D0 (en) 2004-11-11 2004-12-15 Danisco Transcription factors
US8809287B2 (en) * 2004-11-15 2014-08-19 Icahn School Of Medicine At Mount Sinai Compositions and methods for altering Wnt autocrine signaling
DE602005023705D1 (de) 2004-11-18 2010-11-04 Eppendorf Array Technologies Echtzeit-pcr von zielen auf einem mikroarray
CA2589885A1 (en) 2004-12-03 2006-06-08 Schering Corporation Biomarkers for pre-selection of patients for anti-igf1r therapy
US7465587B2 (en) * 2004-12-03 2008-12-16 Genzyme Corporation Diagnostic assay device
US20060205012A1 (en) 2004-12-09 2006-09-14 Meso Scale Technologies, Llc Diagnostic test
US7504769B2 (en) * 2004-12-16 2009-03-17 E. I. Du Pont De Nemours + Company Aromatic chalcogen compounds and their use
US7387890B2 (en) * 2004-12-16 2008-06-17 Chembio Diagnostic Systems, Inc. Immunoassay devices and use thereof
JP5616572B2 (ja) 2004-12-17 2014-10-29 モナッシュ ユニバーシティ 哺乳類修飾ａｄａｍ１０プロテアーゼまたはそのフラグメント、単離核酸、遺伝子構築物、宿主細胞、抗体、及び産生方法
US7682817B2 (en) * 2004-12-23 2010-03-23 Kimberly-Clark Worldwide, Inc. Microfluidic assay devices
US8697674B2 (en) 2004-12-29 2014-04-15 Naturon, Inc. Xanthurenic acid derivative pharmaceutical compositions and methods related thereto
JP4004505B2 (ja) * 2005-01-11 2007-11-07 富士フイルム株式会社 流路部材及びセンサユニット
EP1853914B1 (en) 2005-01-25 2015-04-22 The Johns Hopkins University Plasmodium diagnostic assay
US7700738B2 (en) 2005-01-27 2010-04-20 The Regents Of The University Of California Therapeutic monoclonal antibodies that neutralize botulinum neurotoxins
US20060292700A1 (en) * 2005-06-22 2006-12-28 Naishu Wang Diffused interrupted lateral flow immunoassay device and method
CN103497993A (zh) 2005-02-07 2014-01-08 基因信息公司 轻度骨关节炎生物标志物及其用途
GB0503546D0 (en) * 2005-02-21 2005-03-30 Hellenic Pasteur Inst Antibody
US7189522B2 (en) 2005-03-11 2007-03-13 Chembio Diagnostic Systems, Inc. Dual path immunoassay device
WO2006098804A2 (en) 2005-03-11 2006-09-21 Chembio Diagnostic Systems, Inc. Dual path immunoassay device
US7939342B2 (en) 2005-03-30 2011-05-10 Kimberly-Clark Worldwide, Inc. Diagnostic test kits employing an internal calibration system
NZ562453A (en) 2005-03-31 2010-04-30 Agensys Inc Antibodies and related molecules that bind to 161P2F10B proteins
US8048638B2 (en) * 2005-04-01 2011-11-01 University Of Florida Research Foundation, Inc. Biomarkers of liver injury
AU2006232370B2 (en) 2005-04-01 2011-10-06 Banyan Biomarkers Biomakers of liver injury
SI3264094T1 (sl) 2005-04-04 2021-04-30 Biogen Ma Inc. Metode za ocenjevanje imunskega odziva na terapevtsko učinkovino
WO2006121569A2 (en) 2005-04-08 2006-11-16 Neose Technologies, Inc. Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants
US20130022979A1 (en) 2005-04-18 2013-01-24 Genesis Genomics Inc. 3.4kb MITOCHONDRIAL DNA DELETION FOR USE IN THE DETECTION OF CANCER
CN101248180B (zh) 2005-04-18 2013-09-25 米托米克斯公司 作为检测日光照射、前列腺癌和其它癌症的诊断工具的线粒体突变及重排
US7803319B2 (en) 2005-04-29 2010-09-28 Kimberly-Clark Worldwide, Inc. Metering technique for lateral flow assay devices
US7858384B2 (en) 2005-04-29 2010-12-28 Kimberly-Clark Worldwide, Inc. Flow control technique for assay devices
US7439079B2 (en) * 2005-04-29 2008-10-21 Kimberly-Clark Worldwide, Inc. Assay devices having detection capabilities within the hook effect region
US20070021433A1 (en) 2005-06-03 2007-01-25 Jian-Qiang Fan Pharmacological chaperones for treating obesity
CN101495650B (zh) 2005-06-20 2015-02-04 领先细胞医疗诊断有限公司 检测单个细胞中的核酸和鉴定异质大细胞群中罕见细胞的方法
NZ564923A (en) 2005-07-07 2012-02-24 Athlomics Pty Ltd Polynucleotide marker genes and their expression, for diagnosis of endotoxemia
US20070015166A1 (en) * 2005-07-14 2007-01-18 Nilsen Thor W Lateral flow methods and devices for detection of nucleic acid binding proteins
US8642330B2 (en) * 2005-08-08 2014-02-04 Onconon, Llc Antibody compositions, methods for treating neoplastic disease and methods for regulating fertility
US20070042504A1 (en) * 2005-08-22 2007-02-22 Yimin Yu Method for determining substance or substances in liquid sample
HRP20170444T1 (hr) 2005-08-31 2017-05-19 Merck Sharp & Dohme Corp. Projektirana anti-il-23 antitijela
US7829347B2 (en) * 2005-08-31 2010-11-09 Kimberly-Clark Worldwide, Inc. Diagnostic test kits with improved detection accuracy
WO2007030560A2 (en) * 2005-09-08 2007-03-15 Philadelphia Health & Education Corporation, D/B/A Drexel University College Of Medicine Identification of modulators of serine protease inhibitor kazal and their use as anti-cancer and anti-viral agents
US7608395B2 (en) 2005-09-15 2009-10-27 Baylor Research Institute Systemic lupus erythematosus diagnostic assay
WO2007041340A2 (en) * 2005-09-30 2007-04-12 The Trustees Of Columbia University In The City Of New York Microfluidic cells with parallel arrays of individual dna molecules
IL172297A (en) 2005-10-03 2016-03-31 Compugen Ltd Soluble vegfr-1 variants for the diagnosis of preeclampsia
WO2007047408A2 (en) * 2005-10-12 2007-04-26 Pathologica, Llc. Promac signature application
US7910381B2 (en) * 2005-10-13 2011-03-22 BioAssay Works Immuno gold lateral flow assay
US7344893B2 (en) * 2005-10-13 2008-03-18 Auric Enterprises, Llc Immuno-gold lateral flow assay
US8153444B2 (en) * 2005-10-13 2012-04-10 Auric Enterprises, Llc Immuno gold lateral flow assay
BRPI0617500B8 (pt) * 2005-10-17 2021-07-27 Spidertech A Div Of Stoecker & Associates A Subsidiary Of The Dermatology Center Llc kit de imunoensaio para a detecção de veneno de loxosceles reclusa
WO2007048074A1 (en) 2005-10-21 2007-04-26 Genenews Inc. Method and apparatus for correlating levels of biomarker products with disease
US20090155850A1 (en) * 2005-10-28 2009-06-18 The Florida International University Board Of Trustees Horse:Human Chimeric Antibodies
WO2007056352A2 (en) 2005-11-07 2007-05-18 The Scripps Research Institute Compositions and methods for controlling tissue factor signaling specificity
DK2564864T3 (en) 2005-11-12 2015-04-07 Trustees Of The Leland Board Of FGF-2 related methods for the diagnosis and treatment of depression
DE212006000071U1 (de) 2005-11-18 2008-07-24 Board of Regents, The University of Texas System, Austin Quantifizierung von Fusionsproteinen und ihrer Aktivität in Folge chromosomaler Translokation
WO2008002462A2 (en) * 2006-06-23 2008-01-03 Micronics, Inc. Methods and devices for microfluidic point-of-care immunoassays
US9056291B2 (en) 2005-11-30 2015-06-16 Micronics, Inc. Microfluidic reactor system
US7763453B2 (en) 2005-11-30 2010-07-27 Micronics, Inc. Microfluidic mixing and analytic apparatus
KR20080080525A (ko) 2005-12-08 2008-09-04 노파르티스 아게 유전자 전사에 대한 ｆｇｆｒ３의 억제제의 효과
US20070134814A1 (en) * 2005-12-09 2007-06-14 Kajander E O Methods and compositions for the detection of calcifying nano-particles, identification and quantification of associated proteins thereon, and correlation to disease
US7279136B2 (en) 2005-12-13 2007-10-09 Takeuchi James M Metering technique for lateral flow assay devices
US7745158B2 (en) * 2005-12-14 2010-06-29 Kimberly-Clark Worldwide, Inc. Detection of secreted aspartyl proteases from Candida species
US7618810B2 (en) 2005-12-14 2009-11-17 Kimberly-Clark Worldwide, Inc. Metering strip and method for lateral flow assay devices
EP2674440B1 (en) 2005-12-16 2019-07-03 IBC Pharmaceuticals, Inc. Multivalent immunoglobulin-based bioactive assemblies
CN101529246B (zh) 2005-12-21 2013-05-15 梅索斯卡莱科技公司 分析装置、方法和试剂
CA2821426A1 (en) 2005-12-22 2007-07-05 Abbott Laboratories Methods and marker combinations for screening for predisposition to lung cancer
US9347945B2 (en) 2005-12-22 2016-05-24 Abbott Molecular Inc. Methods and marker combinations for screening for predisposition to lung cancer
US20090053694A1 (en) * 2005-12-26 2009-02-26 Kriksunov Leo B Photochemically Amplified Bioassay
US7465544B2 (en) * 2006-01-11 2008-12-16 Wisconsin Alumni Research Foundation Synthetic cofactor analogs of S-adenosylmethionine as ligatable probes of biological methylation and methods for their use
EP2216339A1 (en) 2006-01-16 2010-08-11 Compugen Ltd. Novel nucleotide and amino acid sequences, and methods of use thereof for diagnosis
US7871568B2 (en) 2006-01-23 2011-01-18 Quidel Corporation Rapid test apparatus
US7794656B2 (en) 2006-01-23 2010-09-14 Quidel Corporation Device for handling and analysis of a biological sample
EP2526968A3 (en) 2006-01-27 2013-05-22 Biogen Idec MA Inc. Nogo receptor antagonists
US20070179094A1 (en) 2006-01-31 2007-08-02 Bayer Schering Pharma Ag Modulation of MDL-1 activity for treatment of inflammatory disease
EP2468294A1 (en) 2006-02-03 2012-06-27 Crc For Asthma And Airways Ltd A method of modulating cellular activity and agents for use therein
WO2007092563A2 (en) 2006-02-08 2007-08-16 Genzyme Corporation Gene therapy for niemann-pick disease type a
US20070224701A1 (en) * 2006-02-16 2007-09-27 Becton, Dickinson And Company Combination vertical and lateral flow immunoassay device
ES2752137T3 (es) 2006-02-28 2020-04-03 Biogen Ma Inc Métodos para tratar enfermedades inflamatorias y autoinmunes con natalizumab
CA2644110A1 (en) 2006-03-03 2007-09-13 Elan Pharmaceuticals, Inc. Methods of treating inflammatory and autoimmune diseases with natalizumab
WO2007109733A2 (en) 2006-03-21 2007-09-27 The Johns Hopkins University Diagnostic and prognostic markers and treatment strategies for multiple sclerosis
US20070232556A1 (en) * 2006-03-31 2007-10-04 Montine Thomas J Methods and compositions for the treatment of neurological diseases and disorders
EP2386858B1 (en) 2006-04-04 2015-07-15 Singulex, Inc. Highly sensitive system and methods for analysis of troponin
EP3156799B1 (en) 2006-04-04 2024-01-24 Novilux, LLC Analyzer and method for highly sensitive detection of analytes
KR20090029184A (ko) * 2006-04-07 2009-03-20 더 가브먼트 오브 더 유나이티드 스테이츠 오브 아메리카, 리프리젠티드 바이 더 세크러테리, 디파트먼트 오브 헬쓰 앤드 휴먼 서비씨즈 항체 조성물 및 신생물성 질병의 치료 방법
TWI425917B (zh) 2006-04-21 2014-02-11 Senomyx Inc 包含高度鮮味風味劑之可食用組合物及其製造方法
FR2900341B1 (fr) 2006-04-27 2012-09-14 Centre Nat Rech Scient Utilisation de ligands synthetiques multivalents de la nucleoline de surface pour le traitement du cancer
RU2008148308A (ru) * 2006-05-09 2010-06-20 Маск Фаундейшн Фор Рисерч Дивелопмент (Us) Определение диастолической сердечной недостаточности при помощи профилей протеазы и ингибитора протеазы в плазме
EP2046385B1 (en) 2006-07-03 2015-03-25 Charles David Adair Composition for modulating the expression of cell adhesion molecules
US20080026394A1 (en) * 2006-07-11 2008-01-31 Antara Biosciences Inc. Methods of detecting one or more cancer markers
EP2082059A4 (en) * 2006-07-11 2009-11-11 Musc Found For Res Dev PREDICTION OF HEART FAILURE TO MYOCARDIN FARCT BY PROTEASE AND PROTEASE INHIBITOR PROFILE MANUFACTURE
WO2008010934A2 (en) 2006-07-14 2008-01-24 Chemocentryx, Inc. Triazolyl phenyl benzenesulfonamides
US8143374B2 (en) * 2006-08-04 2012-03-27 The General Hospital Corporation Polypeptide derivatives of parathyroid hormone (PTH)
US20110184747A1 (en) * 2006-08-09 2011-07-28 Carmen Bozic Method for distribution of a drug
JP2008043332A (ja) 2006-08-17 2008-02-28 Panomics Inc 組織スライドからの核酸定量
WO2008023840A2 (en) 2006-08-25 2008-02-28 Oncotherapy Science, Inc. Prognostic markers and therapeutic targets for lung cancer
US7951776B2 (en) 2006-09-01 2011-05-31 American Type Culture Collection Methods for treatment of type 1 diabetes
JP2008111824A (ja) * 2006-09-01 2008-05-15 Nox Technologies Inc 腫瘍特異的ｔＮＯＸアイソフォーム及び方法
US7985542B2 (en) * 2006-09-07 2011-07-26 Institut Pasteur Genomic morse code
EP2067043B1 (en) * 2006-09-08 2013-07-17 University of Oxford Clinical diagnosis of hepatic fibrosis using inter-alpha-trypsin inhibitor heavy chain h4
US7569396B1 (en) 2006-09-08 2009-08-04 Purplecow Llc Caffeine detection using internally referenced competitive assays
US8055034B2 (en) 2006-09-13 2011-11-08 Fluidigm Corporation Methods and systems for image processing of microfluidic devices
US8050516B2 (en) * 2006-09-13 2011-11-01 Fluidigm Corporation Methods and systems for determining a baseline during image processing
US20100222228A1 (en) * 2006-10-11 2010-09-02 Janssen Pharmaceutica N.V. Compositions and methods for treating and diagnosing irritable bowel syndrome
EP1912067A1 (en) * 2006-10-12 2008-04-16 Eppendorf Array Technologies S.A. Method for quantification of a target compound obtained from a biological sample upon chips
WO2008051491A2 (en) 2006-10-20 2008-05-02 Danisco Us, Inc. Genencor Division Polyol oxidases
US20080305512A1 (en) * 2006-10-26 2008-12-11 Mattingly Phillip G Assay for cardiac troponin autoantibodies
WO2008051762A2 (en) * 2006-10-26 2008-05-02 Abbott Laboratories Immunoassay of analytes in samples containing endogenous anti-analyte antibodies
US7776605B2 (en) 2006-10-26 2010-08-17 Abbott Laboratories Assay for cardiac troponin autoantibodies
EP2089710B1 (en) 2006-10-27 2014-10-01 Janssen Pharmaceutica NV A method for pharmacologically profiling compounds
JP2010508815A (ja) 2006-11-02 2010-03-25 イエール・ユニバーシテイ 卵母細胞受容能の評価
US8293684B2 (en) * 2006-11-29 2012-10-23 Exiqon Locked nucleic acid reagents for labelling nucleic acids
DK2102239T3 (da) 2006-11-30 2012-05-29 Res Dev Foundation Forbedrede immunoglobulin-biblioteker
WO2008067552A2 (en) * 2006-11-30 2008-06-05 Fluidigm Corporation Method and apparatus for biological sample analysis
US20080138842A1 (en) * 2006-12-11 2008-06-12 Hans Boehringer Indirect lateral flow sandwich assay
AR064333A1 (es) 2006-12-14 2009-04-01 Schering Corp Anticuerpo anti-tslp de diseno
US7935538B2 (en) 2006-12-15 2011-05-03 Kimberly-Clark Worldwide, Inc. Indicator immobilization on assay devices
US8377379B2 (en) 2006-12-15 2013-02-19 Kimberly-Clark Worldwide, Inc. Lateral flow assay device
WO2008085895A2 (en) * 2007-01-04 2008-07-17 Musc Foundation For Research Development Predicting atrial fibrillation recurrence by protease and protease inhibitor profiling
ES2634266T3 (es) * 2007-01-11 2017-09-27 Erasmus University Medical Center Captura de conformación cromosómica circular (4C)
CA2674949A1 (en) 2007-01-12 2008-07-24 J. Marc Simard Targeting ncca-atp channel for organ protection following ischemic episode
EP2450702A3 (en) 2007-01-26 2012-07-25 University Of Louisville Research Foundation, Inc. Methods of detecting autoantibodies for diagnosing and characterizing disorders
US8143046B2 (en) 2007-02-07 2012-03-27 Danisco Us Inc., Genencor Division Variant Buttiauxella sp. phytases having altered properties
KR100855299B1 (ko) * 2007-02-16 2008-08-29 건국대학교 산학협력단 인간 ｉｌ-32 특이 항원결정기를 갖는 단일클론항체,특이항체분비 융합 세포주 및 항체들을 이용한 ｉｌ-32측정법
EP2064242A1 (en) 2007-02-23 2009-06-03 Schering Corporation Engineered anti-il-23p19 antibodies
MX2009009079A (es) 2007-02-23 2009-08-31 Schering Corp Anticuerpos anti-il-23p19 de ingenieria.
BRPI0807991A2 (pt) 2007-02-28 2014-06-17 Schering Corp Anticorpos anti-il-23r elaborados.
US7776618B2 (en) 2007-03-01 2010-08-17 Church & Dwight Co., Inc. Diagnostic detection device
EP2136843A1 (en) 2007-03-12 2009-12-30 Miraculins Inc. Biomarkers of prostate cancer and uses thereof
WO2008118324A2 (en) 2007-03-26 2008-10-02 Macrogenics, Inc. Composition and method of treating cancer with an anti-uroplakin ib antibody
US20100143905A1 (en) * 2007-03-29 2010-06-10 Lane Michael J Methods and compositions for multivalent binding and methods for manufacture of rapid diagnostic tests
SG10201507969PA (en) 2007-03-30 2015-10-29 Engeneic Molecular Delivery Pty Ltd Bacterially-derived, intact minicells that encompass plasmid-free functional nucleic acid for in vivo delivery to mammalian cells
WO2008124670A2 (en) 2007-04-06 2008-10-16 Becton, Dickinson And Company Compositions and methods for the identification of a carbapenemase gene
EP2851091B1 (en) 2007-04-13 2017-12-27 Dana-Farber Cancer Institute, Inc. Methods for treating cancer resistant to ERBB therapeutics
US8003314B2 (en) 2007-04-16 2011-08-23 Diagnostic Hybrids, Inc. Methods for direct fluorescent antibody virus detection in liquids
CA2684998A1 (en) 2007-04-30 2009-01-29 Nanogen, Inc. Multianalyte assay
WO2008137475A2 (en) 2007-05-01 2008-11-13 Research Development Foundation Immunoglobulin fc libraries
US8795682B2 (en) * 2007-05-02 2014-08-05 Emory University Virus-like particles comprising chimeric human immunodeficiency virus (HIV)/mouse mammary tumor virus (MMTV) envelopes
EP2155238B1 (en) 2007-06-05 2016-04-06 Yale University Antibody against d4 domain of the kit receptor and use thereor
ES2609818T3 (es) 2007-06-15 2017-04-24 Xiamen University Anticuerpos monoclonales que se unen a hemaglutinina del virus de la gripe aviar del subtipo H5 y usos de los mismos
US7776877B2 (en) 2007-06-22 2010-08-17 Chemocentryx, Inc. N-(2-(hetaryl)aryl) arylsulfonamides and N-(2-(hetaryl) hetaryl arylsulfonamides
US9102754B2 (en) * 2007-06-28 2015-08-11 University Of Saskatchewan Immunomodulatory compositions and methods for treating disease with modified host defense peptides
ATE548039T1 (de) 2007-07-12 2012-03-15 Chemocentryx Inc Kondensierte heteroarylpyridyl- und phenylbenzensulfonamide als ccr2-modulatoren zur behandlung von entzündungen
WO2009014726A1 (en) 2007-07-26 2009-01-29 The Regents Of The University Of California Methods for enhancing bacterial cell display of proteins and peptides
EP2650009B8 (en) * 2007-08-01 2018-07-18 The General Hospital Corporation Screening methods using G-protein coupled receptors and related compositions
JP5797403B2 (ja) 2007-08-03 2015-10-21 エムユーエスシー ファウンデーション フォー リサーチ ディベロップメント ヒトモノクローナル抗体およびそれを産生する方法
AU2008283902B2 (en) 2007-08-06 2014-03-13 Orion Genomics Llc Novel single nucleotide polymorphisms and combinations of novel and known polymorphisms for determining the allele-specific expression of the IGF2 gene
CA2695960A1 (en) 2007-08-08 2009-03-12 The Board Of Regents Of The University Of Texas System Vegfr-1/nrp-1 targeting peptides
WO2009023676A1 (en) 2007-08-12 2009-02-19 Integrated Dna Technologies, Inc. Microarray system with improved sequence specificity
WO2009023733A1 (en) * 2007-08-13 2009-02-19 Trustees Of Tufts College Methods and microarrays for detecting enteric viruses
WO2009029550A2 (en) * 2007-08-24 2009-03-05 Singulex, Inc. Highly sensitive system and methods for analysis of prostate specific antigen (psa)
DK2769729T3 (en) 2007-09-04 2019-04-23 Compugen Ltd POLYPEPTIDES AND POLYNUCLEOTIDES AND APPLICATIONS THEREOF AS A PHARMACEUTICAL OBJECTIVE FOR THE PRODUCTION OF MEDICINAL PRODUCTS AND BIOTECHNOLOGICAL PRODUCTS
US8053198B2 (en) * 2007-09-14 2011-11-08 Meso Scale Technologies, Llc Diagnostic methods
US8114681B2 (en) 2007-10-05 2012-02-14 Affymetrix, Inc. Highly multiplexed particle-based assays
US8535617B2 (en) * 2007-11-30 2013-09-17 Kimberly-Clark Worldwide, Inc. Blood cell barrier for a lateral flow device
US9103796B2 (en) * 2007-12-14 2015-08-11 Kimberly-Clark Worldwide, Inc. Multi-layered devices for analyte detection
US20090155753A1 (en) * 2007-12-14 2009-06-18 Kimberly-Clark Worldwide, Inc. Behavior Tracking with Tracking Pods
AU2008352940B2 (en) 2007-12-19 2014-06-05 Singulex, Inc. Scanning analyzer for single molecule detection and methods of use
JP5677703B2 (ja) 2008-01-10 2015-02-25 リサーチ ディベロップメント ファウンデーション Ｅｈｒｌｉｃｈｉａｃｈａｆｆｅｅｎｓｉｓにのためのワクチンおよび診断
US20110052501A1 (en) * 2008-01-31 2011-03-03 Liat Dassa Polypeptides and polynucleotides, and uses thereof as a drug target for producing drugs and biologics
US20090196852A1 (en) * 2008-02-04 2009-08-06 Watkinson D Tobin Compositions and methods for diagnosing and treating immune disorders
DK2252312T3 (da) 2008-02-07 2014-06-16 Univ Cornell Fremgangsmåder til forebyggelse eller behandling af insulinresistens
US20090311695A1 (en) * 2008-03-12 2009-12-17 Talat Nasim Method
WO2009151693A2 (en) 2008-03-14 2009-12-17 Eastern Virginia Medical School Imaging mass spectrometry for improved prostate cancer diagnostics
US8993231B2 (en) * 2008-03-18 2015-03-31 Marshall University Research Corporation Methods for stem cell production and therapy
CA3044262C (en) * 2008-03-28 2023-02-28 Mdna Life Sciences Inc. Aberrant mitochondrial dna, associated fusion transcripts and hybridization probes therefor
EP2107125A1 (en) 2008-03-31 2009-10-07 Eppendorf Array Technologies SA (EAT) Real-time PCR of targets on a micro-array
CN106349390B (zh) 2008-04-02 2019-12-10 宏观基因有限公司 Bcr-复合体-特异性抗体和其使用方法
SG189730A1 (en) 2008-04-02 2013-05-31 Macrogenics Inc Her2/neu-specific antibodies and methods of using same
KR101725340B1 (ko) 2008-04-11 2017-04-26 메소 스케일 테크놀러지즈, 엘엘시 분석 장치, 방법 및 시약
GB0807161D0 (en) * 2008-04-18 2008-05-21 Danisco Process
CN102066899A (zh) * 2008-04-23 2011-05-18 卢米耐克斯公司 建立针对生物来源之起始材料中多种分析物的标准品的方法
JP2012500620A (ja) * 2008-04-24 2012-01-12 ザ トラスティーズ オブ コロンビア ユニバーシティー イン ザ シティー オブ ニューヨーク Ｄｎａ分子組織化のための幾何学的パターンおよび脂質二重層、ならびにその使用
WO2009133462A2 (en) 2008-04-30 2009-11-05 Danisco A/S Proteins
BRPI0822661A2 (pt) * 2008-05-22 2015-06-30 Centre Nat Rech Scient Compostos oticamente puros para eficiência terapêutica melhorada
WO2010033279A2 (en) 2008-06-04 2010-03-25 Macrogenics, Inc. Antibodies with altered binding to fcrn and methods of using same
US8476008B2 (en) * 2008-07-23 2013-07-02 Diabetomics, Llc Methods for detecting pre-diabetes and diabetes
US20100021472A1 (en) * 2008-07-25 2010-01-28 Geetha Srikrishna Methods for diagnosing and treating cancer
ES2665245T3 (es) 2008-08-11 2018-04-25 Banyan Biomarkers, Inc. Proceso de detección de biomarcador y ensayo de estado neurológico
CA2734892A1 (en) 2008-08-18 2010-02-25 Seoul National University Industry Foundation Method for controlling cancer metastasis or cancer cell migration by modulating the cellular level of lysyl trna synthetase
GB2464183A (en) * 2008-09-19 2010-04-14 Singulex Inc Sandwich assay
US9434985B2 (en) 2008-09-25 2016-09-06 University Of Massachusetts Methods of identifying interactions between genomic loci
US8101813B2 (en) * 2008-10-30 2012-01-24 Kimberly-Clark Worldwide, Inc. Training progress indicator
EP2350131B1 (en) 2008-11-07 2017-06-07 Research Development Foundation Compositions and methods for the inhibition of cripto/grp78 complex formation and signaling
WO2010061393A1 (en) 2008-11-30 2010-06-03 Compugen Ltd. He4 variant nucleotide and amino acid sequences, and methods of use thereof
US20110287088A1 (en) 2008-12-03 2011-11-24 Research Development Foundation Modulation of olfml-3 mediated angiogenesis
EP2194381B1 (de) 2008-12-03 2015-12-02 Roche Diagnostics GmbH Testelement mit kombinierter Kontroll- und Kalibrationszone
WO2010065867A1 (en) 2008-12-04 2010-06-10 Pioneer Hi-Bred International, Inc. Methods and compositions for enhanced yield by targeted expression of knotted1
EP3059247B1 (en) 2008-12-05 2017-09-20 Abraxis BioScience, LLC Sparc binding peptides and uses thereof
CN102300874B (zh) 2008-12-08 2015-08-05 卡姆普根有限公司 Tmem154多肽和多核苷酸及其作为产生药物和生物制品的药物靶标的用途
WO2010066252A1 (en) 2008-12-09 2010-06-17 Dako Denmark A/S Method for evaluating pre-treatment
WO2010068747A1 (en) 2008-12-12 2010-06-17 University Of Florida Research Foundation, Inc. Cell-based detection of apf through its interaction with ckap4 for diagnosis of interstitial cystitis
WO2010068757A1 (en) 2008-12-12 2010-06-17 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Compositions and methods useful for detecting and treating diseases associated with 16p chromosomal disruptions
US8422740B2 (en) 2009-01-15 2013-04-16 Scott Dylewski Methods for determining a liquid front position on a test strip
US8692873B2 (en) 2009-01-15 2014-04-08 Alverix, Inc. Video-frame data receiver with low frame capture rate
EP3722810A3 (en) 2009-02-11 2021-01-13 Caris MPI, Inc. Molecular profiling of tumors
EP2955234A1 (en) 2009-02-11 2015-12-16 Orion Genomics, LLC Combinations of polymorphisms for determining allele-specific expression of igf2
DE102009010563A1 (de) 2009-02-16 2010-08-26 Matthias W. Engel Vorrichtung zum Nachweis von Analyten in Körperflüssigkeiten
US20110306069A1 (en) 2009-02-19 2011-12-15 Qingyu Wu Corin As A Marker For Heart Failure
US20100240065A1 (en) * 2009-03-18 2010-09-23 Boehringer Ingelheim International Gmbh Prolyl Hydroxylase Compositions and Methods of Use Thereof
US8481698B2 (en) * 2009-03-19 2013-07-09 The President And Fellows Of Harvard College Parallel proximity ligation event analysis
AU2010241947B2 (en) * 2009-03-27 2014-01-16 Gojo Industries, Inc. Compositions and methods for screening and using compounds antagonizing spore-surface interactions
KR101720555B1 (ko) 2009-03-27 2017-03-29 엠디엔에이 라이프 사이언시즈 인코퍼레이티드 이상 미토콘드리아 디엔에이, 관련된 융합 전사물 및 번역 산물 및 이에 대한 하이브리드화 탐침
US20100261292A1 (en) 2009-04-10 2010-10-14 Meso Scale Technologies, Llc Methods for Conducting Assays
US9447467B2 (en) 2009-04-21 2016-09-20 Genetic Technologies Limited Methods for obtaining fetal genetic material
GB0908770D0 (en) 2009-04-24 2009-07-01 Danisco Method
US20120046197A1 (en) 2009-05-01 2012-02-23 Meso Scale Technologies, Llc Biomarkers of therapeutic responsiveness
CA2760569C (en) 2009-05-01 2018-01-02 Dako Denmark A/S New antibody cocktail
US8168396B2 (en) 2009-05-11 2012-05-01 Diabetomics, Llc Methods for detecting pre-diabetes and diabetes using differential protein glycosylation
US20120058916A1 (en) 2009-05-13 2012-03-08 Meso Scale Technologies, Llc. Diagnostic methods for liver disorders
WO2010133967A1 (en) * 2009-05-14 2010-11-25 University Of Oxford Clinical diagnosis of hepatic fibrosis using a novel panel of low abundant human plasma protein biomarkers
CA2761767A1 (en) 2009-05-19 2010-11-25 Danisco A/S Use of amylase and lipolytic enzyme in bread
US20120128673A1 (en) 2009-05-20 2012-05-24 Schering Corporation Modulation of pilr receptors to treat microbial infections
RU2566064C2 (ru) 2009-06-02 2015-10-20 Дзе Борд Оф Риджентс Оф Дзе Юниверсити Оф Техас Систем Идентификация низкомолекулярных соединений, распознаваемых антителами у индивидуумов с нейродегенеративными заболеваниями
US8802427B2 (en) * 2009-06-09 2014-08-12 Church & Dwight Co., Inc. Female fertility test
CA2766009A1 (en) 2009-06-25 2010-12-29 Danisco A/S Variant lipolytic enzymes with improved expression, functionality and/or activity
SG10201505075TA (en) 2009-07-17 2015-07-30 Bioatla Llc Simultaneous, Integrated Selection And Evolution Of Antibody/Protein Performance And Expression In Production Hosts
CA3083798C (en) * 2009-07-27 2023-08-15 Meso Scale Technologies, Llc Assay apparatuses, consumables and methods
EP2459742B1 (en) 2009-07-29 2016-04-06 Pharnext New diagnostic tools for alzheimer disease
CN102574924A (zh) 2009-09-03 2012-07-11 先灵公司 抗-gitr抗体
US8900850B2 (en) * 2009-09-17 2014-12-02 Michael J. Lane Lateral flow based methods and assays for rapid and inexpensive diagnostic tests
WO2011038403A1 (en) 2009-09-28 2011-03-31 Yuling Luo Methods of detecting nucleic acid sequences with high specificity
CA2777053A1 (en) 2009-10-06 2011-04-14 The Board Of Trustees Of The University Of Illinois Human single-chain t cell receptors
ES2666372T3 (es) 2009-10-11 2018-05-04 Biogen Ma Inc. Ensayos relacionados con anti-VLA-4
CA2779223A1 (en) 2009-10-27 2011-05-12 Caris Mpi, Inc. Molecular profiling for personalized medicine
JP6174320B2 (ja) 2009-11-17 2017-08-02 エムユーエスシー ファウンデーション フォー リサーチ ディベロップメント ヒトヌクレオリンに対するヒトモノクローナル抗体
US8592151B2 (en) * 2009-11-17 2013-11-26 Musc Foundation For Research Development Assessing left ventricular remodeling via temporal detection and measurement of microRNA in body fluids
GB0920089D0 (en) 2009-11-17 2009-12-30 Danisco Method
US9733242B2 (en) 2012-10-07 2017-08-15 Sevident, Inc. Devices for capturing analyte
US9910040B2 (en) 2012-07-09 2018-03-06 Sevident, Inc. Molecular nets comprising capture agents and linking agents
BR112012013035A8 (pt) 2009-11-30 2018-04-03 Univ Queensland Technology Fibronectina: quimeras do fator do crescimento
WO2011067711A2 (en) 2009-12-01 2011-06-09 Compugen Ltd Novel heparanase splice variant
US8652788B2 (en) 2009-12-02 2014-02-18 Abbott Laboratories Assay for diagnosis of cardiac myocyte damage
US8835120B2 (en) * 2009-12-02 2014-09-16 Abbott Laboratories Assay for cardiac troponin-T (cTnT)
US8183002B2 (en) * 2009-12-03 2012-05-22 Abbott Laboratories Autoantibody enhanced immunoassays and kits
US20110136141A1 (en) * 2009-12-03 2011-06-09 Abbott Laboratories Peptide reagents and method for inhibiting autoantibody antigen binding
WO2011084357A1 (en) 2009-12-17 2011-07-14 Schering Corporation Modulation of pilr to treat immune disorders
GB0922377D0 (en) 2009-12-22 2010-02-03 Arab Gulf University The Mutant LDL receptor
US11287423B2 (en) 2010-01-11 2022-03-29 Biogen Ma Inc. Assay for JC virus antibodies
NZ600681A (en) 2010-01-11 2014-10-31 Biogen Idec Inc Assay for jc virus antibodies
US9682132B2 (en) 2010-01-26 2017-06-20 Banyan Biomarkers, Inc Compositions and methods relating to argininosucccinate synthetase
CA2787311C (en) 2010-01-27 2017-08-15 Yeda Research And Development Co. Ltd. Antibodies that inhibit metalloproteins
KR101851117B1 (ko) 2010-01-29 2018-04-23 마이크로닉스 인코포레이티드. 샘플-투-앤서 마이크로유체 카트리지
ES2719502T3 (es) 2010-01-29 2019-07-10 Advanced Cell Diagnostics Inc Métodos de detección in situ de ácidos nucleicos
US8574832B2 (en) 2010-02-03 2013-11-05 Massachusetts Institute Of Technology Methods for preparing sequencing libraries
TWI518325B (zh) 2010-02-04 2016-01-21 自治醫科大學 對ａｌｋ抑制劑具有先抗性或後抗性癌症的識別、判斷和治療
JP6046494B2 (ja) 2010-02-08 2016-12-14 アジェンシス，インコーポレイテッド １６１ｐ２ｆ１０ｂタンパク質に結合する抗体薬物コンジュゲート（ａｄｃ）
WO2011106738A2 (en) 2010-02-25 2011-09-01 Fred Hutchinson Cancer Research Center Use of tcr clonotypes as biomarkers for disease
EP2544688B1 (en) 2010-03-02 2016-09-07 President and Fellows of Harvard College Methods and compositions for treatment of angelman syndrome
WO2011114251A1 (en) 2010-03-18 2011-09-22 Danisco A/S Foodstuff
EP2550529B1 (en) 2010-03-23 2021-11-17 Iogenetics, LLC. Bioinformatic processes for determination of peptide binding
US20150231215A1 (en) 2012-06-22 2015-08-20 Randolph J. Noelle VISTA Antagonist and Methods of Use
US10745467B2 (en) 2010-03-26 2020-08-18 The Trustees Of Dartmouth College VISTA-Ig for treatment of autoimmune, allergic and inflammatory disorders
MX342017B (es) 2010-03-26 2016-09-09 Dartmouth College Proteina mediadora de celula t regulatoria vista, agentes de enlace de vista y uso de los mismos.
EP2556185B1 (en) 2010-04-06 2021-02-10 Massachusetts Institute of Technology Gene-expression profiling with reduced numbers of transcript measurements
US9125931B2 (en) 2010-04-06 2015-09-08 Massachusetts Institute Of Technology Post-transcriptional regulation of RNA-related processes using encoded protein-binding RNA aptamers
EP3434694B1 (en) 2010-04-09 2020-12-30 Critical Care Diagnostics, Inc. Soluble human st-2 antibodies and assays
JP5786020B2 (ja) 2010-04-16 2015-09-30 アボットジャパン株式会社 関節リウマチを診断する方法および試薬
WO2011133450A2 (en) 2010-04-19 2011-10-27 Meso Scale Technologies, Llc. Serology assays
US10295472B2 (en) 2010-05-05 2019-05-21 Alverix, Inc. Assay reader operable to scan a test strip
MX2012012986A (es) 2010-05-07 2013-03-05 Abbvie Inc Metodos para predecir la sensibilidad al tratamiento con un inhibidor de cinasa de tirosina dirigido.
US20120190563A1 (en) 2010-05-07 2012-07-26 Abbott Laboratories Methods for predicting sensitivity to treatment with a targeted tyrosine kinase inhibitor
WO2011143406A2 (en) 2010-05-13 2011-11-17 The General Hospital Corporation Parathyroid hormone analogs and uses thereof
EP2572197A4 (en) 2010-05-18 2013-08-28 Texas A & M Univ Sys METHOD AND COMPOSITIONS FOR DIAGNOSIS AND MONITORING OF INFLAMMATORY DISEASES
CA2800257C (en) 2010-05-26 2019-03-05 The Board Of Trustees Of The University Of Illinois Personal glucose meters for detection and quantification of a broad range of analytes
US8383580B2 (en) 2010-06-10 2013-02-26 The Regents Of The University Of Michigan Methods of administering lipocalins to treat metabolic disorders and cardiovascular diseases
EP3327035A1 (en) 2010-06-22 2018-05-30 Precision Biologics Inc. Colon and pancreas cancer specific antigens and antibodies
US20130316338A1 (en) 2010-06-29 2013-11-28 The United States Government As Represented By The Department Of Veterans Affairs CCR6 As A Biomarker of Alzheimer's Disease
GB201011513D0 (en) 2010-07-08 2010-08-25 Danisco Method
EP2407242A1 (en) 2010-07-13 2012-01-18 Dublin City University Direct clone analysis and selection technology
EP3435087B1 (en) 2010-07-16 2023-11-08 BioAtla, Inc. Novel methods of protein evolution
CN103153467A (zh) 2010-07-16 2013-06-12 范德比尔特大学 用于提取、浓缩和检测分子物类的使用表面张力阀的低资源处理器
JP5813111B2 (ja) 2010-07-23 2015-11-17 ルミネックス コーポレーション イムノアッセイにおける試薬の反応性を制御するためのコカップリング
US9120862B2 (en) 2010-07-26 2015-09-01 Abbott Laboratories Antibodies relating to PIVKA-II and uses thereof
USD656852S1 (en) 2010-08-06 2012-04-03 Kimberly-Clark Worldwide, Inc. Wetness indicator
US9018434B2 (en) 2010-08-06 2015-04-28 Kimberly-Clark Worldwide, Inc. Absorbent articles with intricate graphics
US8956859B1 (en) 2010-08-13 2015-02-17 Aviex Technologies Llc Compositions and methods for determining successful immunization by one or more vaccines
US8999335B2 (en) 2010-09-17 2015-04-07 Compugen Ltd. Compositions and methods for treatment of drug resistant multiple myeloma
EP2619321B1 (en) 2010-09-20 2018-08-01 Advanced Cell Diagnostics, Inc. Biomarkers for differentiating melanoma from benign nevus in the skin
WO2012040617A2 (en) 2010-09-23 2012-03-29 Neogenix Oncology, Inc. Colon and pancreas cancer peptidomimetics
WO2012040619A2 (en) 2010-09-24 2012-03-29 Massachusetts Eye And Ear Infirmary Methods and compositions for prognosing and/or detecting age-related macular degeneration
KR20250058780A (ko) 2010-09-29 2025-04-30 어젠시스 인코포레이티드 191p4d12 단백질에 결합하는 항체 약물 컨쥬게이트(ａｄｃ)
BR112013008026A2 (pt) 2010-10-04 2016-06-21 Centre Nat Rech Scient composições que compreendem ligantes sintéticos multivalentes de nucleolina de superfície e glicosaminaglicanos
EP2441520A1 (en) 2010-10-12 2012-04-18 Eppendorf AG Real-time amplification and micro-array based detection of nucleic acid targets in a flow chip assay
EP3644058A1 (en) 2010-10-14 2020-04-29 Meso Scale Technologies, LLC Reagent storage in an assay device
US8658361B2 (en) 2010-10-21 2014-02-25 Advanced Cell Diagnostics, Inc. Ultra sensitive method for in situ detection of nucleic acids
AR084358A1 (es) 2010-12-27 2013-05-08 Lilly Co Eli Composiciones y metodos para identificar y diferenciar componentes virales de vacunas multivalentes de la “fiebre de embarque” (complejo de enfermedad respiratoria bovina (brdc))
US9220640B2 (en) 2010-12-30 2015-12-29 Kimberly-Clark Worldwide, Inc. Absorbent article including two dimensional code made from an active graphic
US10670608B2 (en) 2010-12-31 2020-06-02 Bioatla, Llc Comprehensive monoclonal antibody generation
DK2665833T3 (en) 2011-01-17 2017-07-24 Life Technologies Corp WORKING PROCEDURE FOR DETECTING LIGANDS USING NUCLEIC ACIDS
JP2014507649A (ja) 2011-01-18 2014-03-27 バクスター・インターナショナル・インコーポレイテッド ヒト血液中の抗βアミロイド抗体の測定
EP2477032A1 (en) 2011-01-18 2012-07-18 Baxter International Inc Measurement of anti-amyloid antibodies in human blood
US8486717B2 (en) 2011-01-18 2013-07-16 Symbolics, Llc Lateral flow assays using two dimensional features
DK2668290T3 (en) 2011-01-28 2017-09-18 Advanced Cell Diagnostics Inc RNASCOPE® HPV ASSAY FOR DETERMINING HPV STATUS OF CANCER AND HEALTH CANCER AND LESSIONS
CA2826467C (en) 2011-02-07 2019-11-12 Research Development Foundation Engineered immunoglobulin fc polypeptides
US8603835B2 (en) 2011-02-10 2013-12-10 Chembio Diagnostic Systems, Inc. Reduced step dual path immunoassay device and method
WO2012116073A2 (en) 2011-02-23 2012-08-30 The Board Of Trustees Of The University Of Illinois Amphiphilic dendron-coils, micelles thereof and uses
US9057107B2 (en) 2011-03-08 2015-06-16 King Abdullah University Of Science And Technology Molecular biomarker set for early detection of ovarian cancer
AU2012229156A1 (en) 2011-03-11 2013-10-31 Board Of Regents Of The University Of Nebraska Biomarker for coronary artery disease
WO2012131594A1 (en) 2011-03-28 2012-10-04 Novartis Ag Markers associated with cyclin-dependent kinase inhibitors
BR112013025415B1 (pt) 2011-04-01 2021-03-16 Immunogen, Inc uso de um imunoconjugado antirreceptor de folato 1 (folr1)
DK2694095T3 (en) 2011-04-05 2018-05-28 Longevity Biotech Inc COMPOSITIONS COMPREHENSIVE GLUCAGON ANALOGS AND METHODS FOR PREPARING AND USING THE SAME
BR112013025811A2 (pt) 2011-04-08 2016-11-29 Danisco Us Inc "composição e método para remover uma mancha de base lipídica de uma superfície"
NZ616308A (en) 2011-04-08 2016-03-31 Biogen Ma Inc Biomarkers predictive of therapeutic responsiveness to ifnβ and uses thereof
WO2012142164A1 (en) 2011-04-12 2012-10-18 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Human monoclonal antibodies that bind insulin-like growth factor (igf) i and ii
MX2013011978A (es) 2011-04-15 2015-06-10 Compugen Ltd Polipeptidos y polinucleotidos, y usos de los mismos para el tratamiento de transtornos inmunorelacionados y cancer.
US9506051B2 (en) 2011-05-20 2016-11-29 Oligomerix, Inc. Tau protease compositions and methods of use
CN107102135A (zh) 2011-05-20 2017-08-29 阿波特日本有限公司 用于减少非特异性结合的免疫检验方法和试剂
CA2837184C (en) 2011-05-25 2021-09-21 Innate Pharma, S.A. Anti-kir antibodies for the treatment of inflammatory and autoimmune disorders
EP3575792B1 (en) 2011-05-31 2022-11-30 Biogen MA Inc. Method of assessing risk of pml
JP2014527036A (ja) 2011-06-27 2014-10-09 ザ ジャクソン ラボラトリー 癌および自己免疫疾患の処置のための方法および組成物
US9428574B2 (en) 2011-06-30 2016-08-30 Compugen Ltd. Polypeptides and uses thereof for treatment of autoimmune disorders and infection
WO2013010170A1 (en) 2011-07-14 2013-01-17 Lovell Mark A Process for detection of alzheimer's disease from a serum sample
GB201112091D0 (en) 2011-07-14 2011-08-31 Gt Biolog Ltd Bacterial strains isolated from pigs
AU2012284097B2 (en) 2011-07-18 2017-08-03 President And Fellows Of Harvard College Engineered microbe-targeting molecules and uses thereof
WO2013022599A1 (en) 2011-08-05 2013-02-14 Research Development Foundation Improved methods and compositions for modulation of olfml3 mediated angiogenesis
CN103906535B (zh) 2011-08-15 2017-07-14 芝加哥大学 与葡萄球菌蛋白a的抗体相关的组合物和方法
EP2748192B2 (en) 2011-08-23 2022-04-20 Foundation Medicine, Inc. Kif5b-ret fusion molecules and uses thereof
EP2771349B1 (en) 2011-09-16 2020-02-26 Iogenetics, LLC. Bioinformatic processes for determination of peptide binding
CN103959058B (zh) 2011-09-22 2015-12-09 医药生命融合研究团 亮氨酰tRNA合成酶的新用途
EP3511717A3 (en) 2011-09-29 2019-09-25 Meso Scale Technologies, LLC. Biodosimetry panels and methods
GB201117313D0 (en) 2011-10-07 2011-11-16 Gt Biolog Ltd Bacterium for use in medicine
WO2013056178A2 (en) 2011-10-14 2013-04-18 Foundation Medicine, Inc. Novel estrogen receptor mutations and uses thereof
US20130164217A1 (en) 2011-12-21 2013-06-27 Meso Scale Technologies, Llc Method of diagnosing, preventing and/or treating dementia & related disorders
WO2013101758A1 (en) 2011-12-29 2013-07-04 Baylor Research Institute Biomarkers for kawasaki disease
EP2802417B1 (en) 2012-01-09 2019-05-15 Micronics, Inc. Microfluidic reactor system
AU2012367247B2 (en) 2012-01-24 2018-04-05 Cd Diagnostics, Inc. System for detecting infection in synovial fluid
GB201201314D0 (en) 2012-01-26 2012-03-07 Isis Innovation Composition
WO2013114367A2 (en) 2012-02-01 2013-08-08 Compugen Ltd. C10rf32 antibodies, and uses thereof for treatment of cancer
US9567642B2 (en) 2012-02-02 2017-02-14 Massachusetts Institute Of Technology Methods and products related to targeted cancer therapy
EP3415919B1 (en) 2012-02-07 2020-07-29 Intuitive Biosciences Inc. Mycobacterium tuberculosis specific peptides for detection of infection or immunization in non-human primates
BR112014021148B1 (pt) 2012-02-29 2022-07-26 Chemocentryx, Inc Pirazol-1-il benzeno sulfonamidas como antagonistas de ccr9, sua composição e método de modular função ccr (9) em uma célula
SI2828284T1 (sl) 2012-03-20 2019-10-30 Biogen Ma Inc Virus JC nevtralizirajoča protitelesa
WO2013148259A1 (en) 2012-03-28 2013-10-03 Massachusetts Institute Of Technology Cancer-related extracellular matrix signatures and related methods and products
US10024860B2 (en) 2012-03-28 2018-07-17 Massachusetts Institute Of Technology Cancer-related extracellular matrix signatures and related methods and products
US20140178869A1 (en) 2012-04-05 2014-06-26 Advanced Cell Diagnostics, Inc. Detection of immunoglobulin light chain restriction by rna in situ hybridization
US20130280696A1 (en) 2012-04-23 2013-10-24 Elliott Millenson Devices and methods for detecting analyte in bodily fluid
AU2013252888B2 (en) 2012-04-26 2018-06-14 University Of Chicago Compositions and methods related to antibodies that neutralize coagulase activity during Staphylococcus aureus disease
ES2749200T3 (es) 2012-05-10 2020-03-19 Bioatla Llc Anticuerpos monoclonales multiespecíficos
MX369626B (es) 2012-05-24 2019-11-13 Mountgate Group Ltd Composiciones y metodos relacionados con la prevencion y el tratamiento de infecciones por rabia.
LT2854910T (lt) 2012-06-01 2020-05-25 Icahn School Of Medicine At Mount Sinai Ceramido lygiai infekcijos gydymo ir prevencijos metu
AU2013277971B2 (en) 2012-06-22 2018-11-15 Htg Molecular Diagnostics, Inc. Molecular malignancy in melanocytic lesions
US9890215B2 (en) 2012-06-22 2018-02-13 King's College London Vista modulators for diagnosis and treatment of cancer
JP6285923B2 (ja) 2012-06-22 2018-02-28 トラスティーズ・オブ・ダートマス・カレッジ 新規ＶＩＳＴＡ−Ｉｇコンストラクト及び自己免疫、アレルギー性及び炎症性障害の処置のためのＶＩＳＴＡ−Ｉｇの使用
ES2776365T3 (es) 2012-07-09 2020-07-30 Novartis Ag Biomarcadores asociados con inhibidores de CDK
US9651549B2 (en) 2012-07-13 2017-05-16 Genisphere, Llc Lateral flow assays using DNA dendrimers
WO2014014788A2 (en) 2012-07-18 2014-01-23 President And Fellows Of Harvard College Modification of surfaces for simulataneous repellency and targeted binding of desired moieties
US9874556B2 (en) 2012-07-18 2018-01-23 Symbolics, Llc Lateral flow assays using two dimensional features
KR102499753B1 (ko) 2012-07-27 2023-02-16 더 보오드 오브 트러스티스 오브 더 유니버시티 오브 일리노이즈 Ｔ 세포 수용체 조작
US20150159222A1 (en) 2012-07-31 2015-06-11 Novartis Ag Markers associated with human double minute 2 inhibitors
CA3163776A1 (en) 2012-08-03 2014-02-06 Foundation Medicine, Inc. Human papilloma virus as predictor of cancer prognosis
KR102274722B1 (ko) 2012-08-23 2021-07-09 어젠시스 인코포레이티드 158p1d7 단백질에 결합하는 항체
EP3552628A1 (en) 2012-09-07 2019-10-16 The Trustees Of Dartmouth College Vista modulators for diagnosis and treatment of cancer
WO2014043633A1 (en) 2012-09-17 2014-03-20 Agios Pharmaceuticals, Inc. Use of e-cadherin and vimentin for selection of treatment responsive patients
CA2887933A1 (en) 2012-10-12 2014-04-17 Arizona Board Of Agents, On Behalf Of Arizona State University Antibody based reagents that specifically recognize toxic oligomeric forms of tau
WO2014063097A1 (en) 2012-10-19 2014-04-24 Danisco Us Inc. Stabilization of biomimetic membranes
US9395369B2 (en) 2012-10-19 2016-07-19 Regents Of The University Of Minnesota Guinea pig cytomegalovirus (CIDMTR strain)
US20150354006A1 (en) 2012-10-19 2015-12-10 Novartis Ag Markers for acute lymphoblastic leukemia
CA2888345C (en) 2012-10-24 2020-04-21 Research Development Foundation Jam-c antibodies and methods for treatment of cancer
AU2013334493B2 (en) 2012-10-26 2018-11-29 The University Of Queensland Use of endocytosis inhibitors and antibodies for cancer therapy
BR112015010220A2 (pt) 2012-11-05 2017-12-05 Pronai Therapeutics Inc métodos de utilização de biomarcadores para tratamento de câncer
CA2890346A1 (en) 2012-11-05 2014-05-08 Foundation Medicine, Inc. Novel fusion molecules and uses thereof
AU2013337277B2 (en) 2012-11-05 2018-03-08 Foundation Medicine, Inc. Novel NTRK1 fusion molecules and uses thereof
KR20150085078A (ko) 2012-11-21 2015-07-22 아지오스 파마슈티컬스 아이엔씨. 글루타마제 억제제 및 사용 방법
CN104937106A (zh) 2012-11-21 2015-09-23 奥斯陆大学医院 用于监测生物流体的系统和方法
WO2014079011A1 (en) 2012-11-22 2014-05-30 Agios Pharmaceuticals, Inc. Heterocyclic compounds for inhibiting glutaminase and their methods of use
US20150346097A1 (en) 2012-12-21 2015-12-03 Micronics, Inc. Portable fluorescence detection system and microassay cartridge
US10065186B2 (en) 2012-12-21 2018-09-04 Micronics, Inc. Fluidic circuits and related manufacturing methods
US10518262B2 (en) 2012-12-21 2019-12-31 Perkinelmer Health Sciences, Inc. Low elasticity films for microfluidic use
WO2014106176A1 (en) 2012-12-28 2014-07-03 Precision Biologics, Inc. Humanized monoclonal antibodies and methods of use for the diagnosis and treatment of colon and pancreas cancer
CN105008925B (zh) 2013-01-02 2017-09-26 N-Dia有限责任公司 预测孕妇分娩时间的方法
CA3107353C (en) 2013-01-04 2024-05-28 Meso Scale Technologies, Llc. Assay apparatuses, methods and reagents
US10980804B2 (en) 2013-01-18 2021-04-20 Foundation Medicine, Inc. Methods of treating cholangiocarcinoma
US8968677B2 (en) 2013-01-22 2015-03-03 Quantum Design International, Inc. Frazil ice conjugate assay device and method
US10125373B2 (en) 2013-01-22 2018-11-13 Arizona Board Of Regents On Behalf Of Arizona State University Geminiviral vector for expression of rituximab
US20140309263A1 (en) 2013-02-01 2014-10-16 Meso Scale Technologies, Llc Biomarkers of therapeutic responsiveness
CA3209385A1 (en) 2013-02-01 2014-08-07 The Regents Of The University Of California Methods for genome assembly and haplotype phasing
AU2014212230B2 (en) 2013-02-01 2019-07-04 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Method for generating retinal pigment epithelium (RPE) cells from induced pluripotent stem cells (iPSCs)
US20140221368A1 (en) 2013-02-01 2014-08-07 Meso Scale Technologies, Llc Biomarkers of therapeutic responsiveness
US20140221325A1 (en) 2013-02-01 2014-08-07 Meso Scale Technologies, Llc Glomerulonephritis biomarkers
US9411930B2 (en) 2013-02-01 2016-08-09 The Regents Of The University Of California Methods for genome assembly and haplotype phasing
WO2014130846A1 (en) 2013-02-22 2014-08-28 Seungpyo Hong Transdermal drug delivery using amphiphilic dendron-coil micelles
TWI582239B (zh) 2013-03-11 2017-05-11 諾華公司 與ｗｎｔ抑制劑相關之標記
US9273349B2 (en) 2013-03-14 2016-03-01 Affymetrix, Inc. Detection of nucleic acids
EP2970479B1 (en) 2013-03-14 2019-04-24 Novartis AG Antibodies against notch 3
WO2014159242A1 (en) 2013-03-14 2014-10-02 Novartis Ag Notch 3 mutants and uses thereof
US9789164B2 (en) 2013-03-15 2017-10-17 Longevity Biotech, Inc. Peptides comprising non-natural amino acids and methods of making and using the same
EP3404116B1 (en) 2013-03-15 2022-10-19 The University of Chicago Methods and compositions related to t-cell activity
JP2016515534A (ja) 2013-03-15 2016-05-30 ヴェロ バイオ，エルエルシー 子癇症及び子癇前症を治療するための方法
EP4174082A1 (en) 2013-03-15 2023-05-03 GLAdiator Biosciences, Inc. Gla domains as targeting agents
ES2751391T3 (es) 2013-03-21 2020-03-31 Univ Michigan Regents Procedimientos de tratamiento de trastornos metabólicos
EP2976109B1 (en) 2013-03-21 2018-07-25 Genisphere, LLC Cellular delivery of dna intercalating agents
GB201306536D0 (en) 2013-04-10 2013-05-22 Gt Biolog Ltd Polypeptide and immune modulation
EP2986326B1 (en) 2013-04-15 2018-09-05 Cedars-Sinai Medical Center Methods for detecting cancer metastasis
US9588114B2 (en) 2013-04-23 2017-03-07 Montecito Bio Sciences Ltd Flow through testing system with pressure indicator
US20160091485A1 (en) 2013-04-25 2016-03-31 The Broad Institute, Inc. Markers for ezh2 inhibitors
EP2994167B1 (en) 2013-05-06 2020-05-06 Alnylam Pharmaceuticals, Inc. Dosages and methods for delivering lipid formulated nucleic acid molecules
WO2014182847A1 (en) 2013-05-07 2014-11-13 Micronics, Inc. Device for preparation and analysis of nucleic acids
WO2014182844A1 (en) 2013-05-07 2014-11-13 Micronics, Inc. Microfluidic devices and methods for performing serum separation and blood cross-matching
JP6472788B2 (ja) 2013-05-07 2019-02-20 マイクロニクス， インコーポレイテッド 粘土鉱物およびアルカリ性溶液を使用して核酸含有試料を調製するための方法
GB201308658D0 (en) 2013-05-14 2013-06-26 Isis Innovation Antibodies
JP6649250B2 (ja) 2013-05-21 2020-02-19 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ 操作されたヘム結合性構成物およびその使用
HK1216546A1 (zh) 2013-05-28 2016-11-18 Biogen Ma Inc. 评估pml风险的方法
US9442051B2 (en) * 2013-06-10 2016-09-13 Yingjian Wang Methods to accelerate the binding of biological molecules
EP3008201B1 (en) 2013-06-12 2019-08-07 The General Hospital Corporation Methods for multiplexed detection of target molecules and uses thereof
DK3010519T3 (en) 2013-06-18 2021-05-17 Dnatrix Inc Oncolytic adenovirus for use in a treatment of brain cancer
US20160296609A1 (en) 2013-06-28 2016-10-13 Baylor Research Institute Dendritic cell asgpr targeting immunotherapeutics for multiple sclerosis
HK1224331A1 (zh) 2013-07-17 2017-08-18 Foundation Medicine, Inc. 治疗尿路上皮癌的方法
TWI646108B (zh) 2013-08-01 2019-01-01 艾澤西公司 結合至ｃｄ３７蛋白質之抗體藥物結合物（ａｄｃ）
US20150038365A1 (en) 2013-08-01 2015-02-05 Meso Scale Technologies, Llc Lung cancer biomarkers
CN114621346B (zh) 2013-08-21 2025-06-10 德克萨斯州大学系统董事会 用于靶向连接蛋白半通道的组合物和方法
PL3038650T3 (pl) 2013-08-30 2021-11-22 Immunogen, Inc. Przeciwciała i testy do wykrywania receptora folianu 1
CN105765384B (zh) 2013-09-13 2018-02-09 Symbolics有限责任公司 运用二维试验和对照信号读出模式的侧向层析检测
WO2015050959A1 (en) 2013-10-01 2015-04-09 Yale University Anti-kit antibodies and methods of use thereof
EP3052193B1 (en) 2013-10-03 2018-01-31 Oklahoma Medical Research Foundation Biomarkers for systemic lupus erythematosus disease activity, and intensity and flare
US9476884B2 (en) 2013-10-04 2016-10-25 University Of Massachusetts Hybridization- independent labeling of repetitive DNA sequence in human chromosomes
WO2015063604A2 (en) 2013-11-01 2015-05-07 Imberti Luisa BIOMARKERS PREDICTIVE OF THERAPEUTIC RESPONSIVENESS TO IFNβ AND USES THEREOF
CA2965327C (en) 2013-11-08 2023-05-09 The Board Of Regents Of The University Of Texas System Vh4 antibodies against gray matter neuron and astrocyte
CA2930693A1 (en) 2013-11-15 2015-05-21 The Board Of Trustees Of The Leland Stanford Junior Unversity Methods of treating heart failure with agonists of hypocretin receptor 2
KR20160079891A (ko) 2013-11-20 2016-07-06 유니버시티 오브 아이오와 리써치 파운데이션 아밀로이드 침착의 치료를 위한 방법 및 조성물
AU2014352826B2 (en) 2013-11-22 2019-08-01 The Board Of Trustees Of The University Of Illinois Engineered high-affinity human T cell receptors
EP3663763B1 (en) 2013-11-26 2022-02-16 The Brigham and Women's Hospital, Inc. Compositions and methods for modulating an immune response
US20150191744A1 (en) 2013-12-17 2015-07-09 University Of Massachusetts Cas9 effector-mediated regulation of transcription, differentiation and gene editing/labeling
EP3083658B1 (en) 2013-12-18 2019-05-08 President and Fellows of Harvard College Crp capture/detection of gram positive bacteria
WO2015094527A1 (en) 2013-12-19 2015-06-25 Danisco Us Inc. Use of hydrophobins to increase gas transferin aerobic fermentation processes
US11014987B2 (en) 2013-12-24 2021-05-25 Janssen Pharmaceutics Nv Anti-vista antibodies and fragments, uses thereof, and methods of identifying same
US10273301B2 (en) 2013-12-24 2019-04-30 Janssen Pharmaceutica Nv Anti-vista antibodies and fragments
US11293929B2 (en) 2014-01-07 2022-04-05 Bioatla, Inc. Proteins targeting orthologs
US10286058B2 (en) 2014-01-13 2019-05-14 Baylor Research Institute Vaccines against HPV and HPV-related diseases
EP3099719B1 (en) 2014-01-29 2020-04-01 Dana-Farber Cancer Institute, Inc. Antibodies against the muc1-c/extracellular domain (muc1-c/ecd)
US20150247204A1 (en) 2014-02-07 2015-09-03 The General Hopital Corporation Differential diagnosis of hepatic neoplasms
US20150232935A1 (en) 2014-02-14 2015-08-20 The General Hospital Corporation Methods for diagnosing igg4-related disease
US10955422B2 (en) 2014-02-27 2021-03-23 Biogen Ma, Inc. Method of assessing risk of PML
US20150247205A1 (en) 2014-02-28 2015-09-03 The General Hospital Corporation Diagnosis of multiple myeloma and lymphoma
CA2943339A1 (en) 2014-03-21 2015-09-24 Agios Pharmaceuticals, Inc. Compounds and their methods of use
MX389472B (es) 2014-04-02 2025-03-20 Chembio Diagnostic Systems Inc Inmunoensayo que utiliza un conjugado de captura
CA2983796A1 (en) 2014-04-25 2015-10-29 The Brigham And Women's Hospital, Inc. Compositions and methods for treating subjects with immune-mediated diseases
EP2942627A1 (en) 2014-05-05 2015-11-11 MicroBPlex, Inc. Media elaborated with newly synthesized antibodies (mensa) from recently proliferated antibody secreting cells (asc) and uses thereof
WO2015172083A1 (en) 2014-05-08 2015-11-12 Biogen Ma Inc. Dimethylfumarate and prodrugs for treatment of multiple sclerosis
JP6875129B2 (ja) 2014-05-08 2021-05-19 ノボダイアックス， インコーポレイテッド 直接的な免疫組織化学アッセイ
US20170269075A1 (en) 2014-05-12 2017-09-21 Biogen Ma Inc. Biomarkers predictive of lupus progression and uses thereof
US9568404B2 (en) 2014-05-16 2017-02-14 Junyu Mai Method and apparatus for biomolecule analysis
WO2015179435A1 (en) 2014-05-19 2015-11-26 Bayer Healthcare Llc Optimized humanized monoclonal antibodies against activated protein c and uses thereof
US11123426B2 (en) 2014-06-11 2021-09-21 The Trustees Of Dartmouth College Use of vista agonists and antagonists to suppress or enhance humoral immunity
GB201413240D0 (en) 2014-07-25 2014-09-10 Hansa Medical Ab Method
EP4219710A3 (en) 2014-08-01 2023-08-16 Dovetail Genomics, LLC Tagging nucleic acids for sequence assembly
WO2016026978A1 (en) 2014-08-22 2016-02-25 Universite Nice Sophia Antipolis Methods and pharmaceutical compositions for treating drug addiction
WO2016038550A1 (en) 2014-09-11 2016-03-17 Novartis Ag Inhibition of prmt5 to treat mtap-deficiency-related diseases
US10759860B2 (en) 2014-09-16 2020-09-01 Synermore Biologics Co., Ltd. Anti-EGFR antibody and uses of same
RU2713653C2 (ru) 2014-10-06 2020-02-06 Кемосентрикс, Инк. КОМБИНИРОВАННАЯ ТЕРАПИЯ ИНГИБИТОРАМИ С-С ХЕМОКИНОВОГО РЕЦЕПТОРА 9 (CCR9) И АНТИТЕЛАМИ, БЛОКИРУЮЩИМИ α4β7-ИНТЕГРИН
IL279420B2 (en) 2014-10-08 2024-09-01 Novartis Ag Biomarkers predictive of therapeutic responsiveness to chimeric antigen receptor therapy and uses thereof
EP3207156A1 (en) 2014-10-13 2017-08-23 Life Technologies Corporation Methods, kits & compositions for determining gene copy numbers
US20170306360A1 (en) 2014-10-24 2017-10-26 Danisco Us Inc. Method for producing alcohol by use of a tripeptidyl peptidase
DK3209773T3 (da) 2014-10-24 2020-06-15 Dupont Nutrition Biosci Aps Prolintolerante tripeptidylpeptidaser og anvendelser deraf
US20160116466A1 (en) 2014-10-27 2016-04-28 Chembio Diagnostic Systems, Inc. Rapid Screening Assay for Qualitative Detection of Multiple Febrile Illnesses
EP3227462B1 (en) 2014-12-01 2020-04-22 The Broad Institute, Inc. Method for in situ determination of nucleic acid proximity
US10479997B2 (en) 2014-12-01 2019-11-19 Novartis Ag Compositions and methods for diagnosis and treatment of prostate cancer
MX2017007136A (es) 2014-12-05 2017-12-04 Immunext Inc Identificacion de vsig8 como el receptor vista putativo y su uso para producir moduladores vista/vsig8.
AU2015360694B2 (en) 2014-12-08 2021-10-14 Berg Llc Use of markers including filamin a in the diagnosis and treatment of prostate cancer
BR112017013274A2 (pt) 2014-12-23 2018-02-06 4D Pharma Research Limited polipeptídeo e imunomodulação
CN108138122B (zh) 2014-12-23 2021-09-21 4D制药研究有限公司 免疫调控
EP3256490A1 (en) 2015-02-09 2017-12-20 Research Development Foundation Engineered immunoglobulin fc polypeptides displaying improved complement activation
GB201502305D0 (en) 2015-02-12 2015-04-01 Hansa Medical Ab Protein
GB201502306D0 (en) 2015-02-12 2015-04-01 Hansa Medical Ab Protein
SG11201706730XA (en) 2015-02-17 2017-09-28 Dovetail Genomics Llc Nucleic acid sequence assembly
CA2977499C (en) 2015-02-25 2023-10-03 Vanderbilt University Antibody-mediated neutralization of marburg virus
UA122331C2 (uk) 2015-03-09 2020-10-26 Едженсіс, Інк. Антитіло проти flt3 та кон'югат антитіло-лікарський засіб (adc), який зв'язується з білком flt3
EP3268462B1 (en) 2015-03-11 2021-08-11 The Broad Institute, Inc. Genotype and phenotype coupling
GB2554572B (en) 2015-03-26 2021-06-23 Dovetail Genomics Llc Physical linkage preservation in DNA storage
US9612534B2 (en) 2015-03-31 2017-04-04 Tokyo Electron Limited Exposure dose homogenization through rotation, translation, and variable processing conditions
US11279768B1 (en) 2015-04-03 2022-03-22 Precision Biologics, Inc. Anti-cancer antibodies, combination therapies, and uses thereof
US9927443B2 (en) 2015-04-10 2018-03-27 Conquerab Inc. Risk assessment for therapeutic drugs
CA2983732A1 (en) 2015-04-23 2016-10-27 Board Of Regents Of The Nevada System Of Higher Education, On Behalf Of The University Of Nevada, Reno Fungal detection using mannan epitope
EP3091026B1 (en) 2015-05-08 2019-02-20 Centrillion Technology Holdings Corporation Disulfide-linked reversible terminators
US10787516B2 (en) 2015-05-18 2020-09-29 Agensys, Inc. Antibodies that bind to AXL proteins
JP6913030B2 (ja) 2015-05-18 2021-08-04 アジェンシス，インコーポレイテッド Ａｘｌタンパク質に結合する抗体
MA41060B1 (fr) 2015-06-15 2019-11-29 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
ME03511B (me) 2015-06-15 2020-04-20 4D Pharma Res Ltd Kompozicije koje sadrže bakterijske sojeve
MA41010B1 (fr) 2015-06-15 2020-01-31 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
PT3307288T (pt) 2015-06-15 2019-10-17 4D Pharma Res Ltd Composições compreendendo estirpes bacterianas
HRP20191949T1 (hr) 2015-06-15 2020-01-24 4D Pharma Research Limited Blautia stercosis i wexlerae za upotrebu u liječenju upalnih i autoimunih bolesti
CN114805576A (zh) 2015-06-24 2022-07-29 詹森药业有限公司 抗vista抗体和片段
JP2018518976A (ja) 2015-06-26 2018-07-19 デュポン ニュートリション バイオサイエンシス エーピーエス タンパク質加水分解用アミノペプチダーゼ
JP2018523469A (ja) 2015-07-10 2018-08-23 ウエストバージニア ユニバーシティＷｅｓｔ Ｖｉｒｇｉｎｉａ Ｕｎｉｖｅｒｓｉｔｙ 脳卒中および脳卒中重篤度のマーカー
US10877045B2 (en) 2015-07-21 2020-12-29 Saint Louis University Compositions and methods for diagnosing and treating endometriosis-related infertility
AU2016301231A1 (en) 2015-08-04 2018-02-22 Cd Diagnostics, Inc. Methods for detecting adverse local tissue reaction (ALTR) necrosis
US10435457B2 (en) 2015-08-06 2019-10-08 President And Fellows Of Harvard College Microbe-binding molecules and uses thereof
DK3785799T3 (da) 2015-08-06 2023-03-06 Lia Diagnostics Inc Fremstillingsfremgangsmåder til vanddispergerbare assays
US11214800B2 (en) 2015-08-18 2022-01-04 The Broad Institute, Inc. Methods and compositions for altering function and structure of chromatin loops and/or domains
ES2890073T3 (es) 2015-08-25 2022-01-17 Prothena Biosciences Ltd Métodos para detectar alfa-sinucleína fosforilada
US10526408B2 (en) 2015-08-28 2020-01-07 Research Development Foundation Engineered antibody FC variants
WO2017040813A2 (en) 2015-09-02 2017-03-09 University Of Massachusetts Detection of gene loci with crispr arrayed repeats and/or polychromatic single guide ribonucleic acids
JP6905163B2 (ja) 2015-09-03 2021-07-21 ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア サイトカイン放出症候群を予測するバイオマーカー
WO2017044419A1 (en) 2015-09-08 2017-03-16 University Of Massachusetts Dnase h activity of neisseria meningitidis cas9
WO2017053567A1 (en) 2015-09-22 2017-03-30 Delta Tm Technologies Designing customized protein-specific buffer systems
CN108368554B (zh) 2015-09-29 2022-09-09 Htg分子诊断有限公司 弥漫性大b细胞淋巴瘤(dlbcl)亚型分型的方法
EP3347373A1 (en) 2015-10-10 2018-07-18 Intrexon Corporation Improved therapeutic control of proteolytically sensitive, destabilized forms of interleukin-12
EP3362462B1 (en) 2015-10-12 2021-07-21 Advanced Cell Diagnostics, Inc. In situ detection of nucleotide variants in high noise samples, and compositions and methods related thereto
US9377457B1 (en) 2015-10-19 2016-06-28 Naishu Wang Progressive compression driven flow cartridge for analyte detecting strip and method
KR20180096586A (ko) 2015-10-19 2018-08-29 더브테일 제노믹스 엘엘씨 게놈 어셈블리, 하플로타입 페이징 및 표적 독립적 핵산 검출을 위한 방법
EP3371321A1 (en) 2015-11-06 2018-09-12 Oslo Universitetssykehus HF Methods and devices for detecting methanol poisoning using formate oxidase
PL3373968T3 (pl) 2015-11-09 2024-08-05 The Children's Hospital Of Philadelphia Glipikan 2 jako marker nowotworowy i cel terapeutyczny
GB201520497D0 (en) 2015-11-20 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
SI3209310T1 (en) 2015-11-20 2018-06-29 4D Pharma Research Limited Compositions containing bacterial strains
GB201520638D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
GB201520631D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
WO2017096017A1 (en) 2015-12-02 2017-06-08 Stsciences, Inc. Antibodies specific to glycosylated btla (b- and t- lymphocyte attenuator)
AU2016365318B2 (en) 2015-12-02 2024-04-18 Board Of Regents, The University Of Texas System Antibodies and molecules that immunospecifically bind to BTN1A1 and the therapeutic uses thereof
ES2902477T3 (es) 2015-12-04 2022-03-28 Univ Texas Péptidos SLC45A2 para inmunoterapia
WO2017100454A1 (en) 2015-12-09 2017-06-15 Intuitive Biosciences, Inc. Automated silver enhancement system
JOP20200228A1 (ar) 2015-12-21 2017-06-16 Novartis Ag تركيبات وطرق لخفض تعبير البروتين tau
US10920224B2 (en) 2015-12-22 2021-02-16 The Regents Of The University Of Colorado, A Body Corporate Protecting RNAs from degradation using engineered viral RNAs
WO2017139415A2 (en) 2016-02-11 2017-08-17 Qiagen Waltham, Inc. Scavenger compounds for improved sequencing-by-synthesis
EP3414338B1 (en) 2016-02-11 2022-12-21 Qiagen Sciences, LLC Polyphenolic additives in sequencing-by-synthesis
MX2018009800A (es) 2016-02-12 2018-11-09 Janssen Pharmaceutica Nv Anticuerpos y fragmentos anti-vista, usos de los mismos y procedimientos de identificacion de los mismos.
EP3414339A4 (en) 2016-02-12 2019-08-28 The Regents of The University of California SYSTEMS AND COMPOSITIONS FOR THE DIAGNOSIS OF A PATHOGENIC FUNGI INFECTION AND METHOD FOR USE THEREOF
WO2017143156A1 (en) 2016-02-19 2017-08-24 Genisphere Llc Nucleic acid carriers and therapeutic methods of use
WO2017147186A1 (en) 2016-02-22 2017-08-31 Ursure, Inc. System and method for detecting therapeutic agents to monitor adherence to a treatment regimen
KR102744506B1 (ko) 2016-02-23 2024-12-18 더브테일 제노믹스 엘엘씨 게놈 어셈블리를 위한 페이징된 판독 세트의 생성 및 반수체형 페이징
EP3420097A1 (en) 2016-02-25 2019-01-02 DuPont Nutrition Biosciences ApS Method for producing a protein hydrolysate employing an aspergillus fumigatus tripeptidyl peptidase
WO2017147561A1 (en) 2016-02-26 2017-08-31 The Board Of Regents Of The University Of Texas System CONNEXIN (Cx) 43 HEMICHANNEL-BINDING ANTIBODIES AND USES THEREOF
HK1258098A1 (zh) 2016-02-29 2019-11-01 Foundation Medicine, Inc. 治疗癌症的方法
CN109196121B (zh) 2016-02-29 2022-01-04 基因泰克公司 用于癌症的治疗和诊断方法
RS58869B1 (sr) 2016-03-04 2019-08-30 4D Pharma Plc Kompozicije koje sadrže blautia bakterijske sojeve za lečenje visceralne hipersenzitivnosti
GB201612191D0 (en) 2016-07-13 2016-08-24 4D Pharma Plc Compositions comprising bacterial strains
US10458995B2 (en) 2016-03-25 2019-10-29 Muralidhar Reddy Moola Combinatorial synthesis and biomarker development
KR102418372B1 (ko) 2016-03-29 2022-07-08 주식회사 에스티큐브 글리코실화된 pd-l1에 특이적인 이중 기능 항체 및 이의 사용 방법
EP3436480A4 (en) 2016-03-30 2019-11-27 Musc Foundation for Research Development METHOD FOR THE TREATMENT AND DIAGNOSIS OF CANCER BY TARGETING GLYCOPROTEIN A REPETITION PREDOMINANT (GARP) AND FOR EFFECTIVE IMMUNOTHERAPY ALONE OR IN COMBINATION
US9903866B2 (en) 2016-04-05 2018-02-27 Conquerab Inc. Portable devices for detection of antibodies against therapeutic drugs
US20190120838A1 (en) 2016-04-13 2019-04-25 Inserm (Institut National De La Sante Et De La Recherche Medicale) Methods and kits for the rapid detection of the escherichia coli o25b-st131 clone
PE20190115A1 (es) 2016-04-15 2019-01-16 Immunext Inc Anticuerpos vista antihumanos y su uso
US9632083B1 (en) 2016-04-15 2017-04-25 Dnt Scientific Research, Llc Rapid diagnostic test device by driven flow technology
US9702872B1 (en) 2016-04-15 2017-07-11 Dnt Scientific Research, Llc Rapid diagnostic test device by driven flow technology
WO2017194589A1 (en) 2016-05-10 2017-11-16 Vib Vzw Inhibition of tau-mediated early synaptic dysfunction
SG11201810088SA (en) 2016-05-13 2018-12-28 Dovetail Genomics Llc Recovering long-range linkage information from preserved samples
AU2017268248A1 (en) 2016-05-16 2018-12-13 President And Fellows Of Harvard College Aqueous biomolecule coupling on CO2-plasma-activated surfaces
AU2017278261A1 (en) 2016-06-05 2019-01-31 Berg Llc Systems and methods for patient stratification and identification of potential biomarkers
US10591480B2 (en) 2016-06-06 2020-03-17 Medizinische Universität Wien Method for the detection of an IgM antibody specific for a flavivirus in a sample
CA3028682A1 (en) 2016-06-20 2017-12-28 Howard Y. Chang Circular rnas and their use in immunomodulation
US9535061B1 (en) 2016-06-29 2017-01-03 Dnt Scientific Research, Llc Multi-functional rapid diagnostic test device
EP3482202A4 (en) 2016-07-11 2020-03-18 Arizona Board of Regents on behalf of Arizona State University USE OF SWEAT AS A BIOFLUID FOR THE ANALYSIS AND IDENTIFICATION OF DISEASES
TWI802545B (zh) 2016-07-13 2023-05-21 英商４Ｄ製藥有限公司 包含細菌菌株之組合物
WO2018017673A1 (en) 2016-07-20 2018-01-25 Stcube, Inc. Methods of cancer treatment and therapy using a combination of antibodies that bind glycosylated pd-l1
EP3488242B1 (en) 2016-07-20 2025-06-11 Vib Vzw Therapeutic agents for neurological and psychiatric disorders
WO2018045162A1 (en) 2016-09-01 2018-03-08 Biogen Ma Inc. Biomarkers predictive of primary progressive multiple sclerosis and uses thereof
CN110366558A (zh) 2016-10-28 2019-10-22 班扬生物标记公司 针对泛素c末端水解酶l1(uch-l1)和胶质纤维酸性蛋白(gfap)的抗体及相关方法
US11021533B2 (en) 2016-11-02 2021-06-01 Vanderbilt University Human Zika virus antibodies and methods of use therefor
US20180128828A1 (en) 2016-11-04 2018-05-10 James W. Stave Direct detection of microorganisms in patient samples by immunoassay
WO2018089231A1 (en) 2016-11-09 2018-05-17 Qiagen Sciences Llc Photoprotective mixtures as imaging reagents in sequencing-by-synthesis
AU2017363299B2 (en) 2016-11-23 2022-12-22 Chemocentryx, Inc. Method of treating focal segmental glomerulosclerosis
WO2018100431A1 (en) 2016-11-29 2018-06-07 Genomic Vision Method for designing a set of polynucleotide sequences for analysis of specific events in a genetic region of interest
GB201621123D0 (en) 2016-12-12 2017-01-25 4D Pharma Plc Compositions comprising bacterial strains
EP3555625A1 (en) 2016-12-16 2019-10-23 Merck Patent GmbH Methods for the use of galectin 3 binding protein detected in the urine for monitoring the severity and progression of lupus nephritis
US10656164B2 (en) 2016-12-22 2020-05-19 Qiagen Sciences, Llc Screening asymptomatic pregnant woman for preterm birth
US10935555B2 (en) 2016-12-22 2021-03-02 Qiagen Sciences, Llc Determining candidate for induction of labor
CN110461872B (zh) 2017-01-26 2023-09-26 再鼎医药(上海)有限公司 Cd47抗原结合单元及其用途
EP3574114B1 (en) 2017-01-26 2022-06-29 Oklahoma Medical Research Foundation Biomarkers for systemic lupus erythematosus disease activity, and intensity and flare
CA3051466A1 (en) 2017-01-31 2018-08-09 Vanderbilt University Generation of human allergen-and helminth-specific ige monoclonal antibodies for diagnostic and therapeutic use
US11179413B2 (en) 2017-03-06 2021-11-23 Novartis Ag Methods of treatment of cancer with reduced UBB expression
WO2018187385A1 (en) 2017-04-03 2018-10-11 The Regents Of The University Of California Compositions and methods of diagnosing pancreatic cancer
WO2018203145A1 (en) 2017-05-03 2018-11-08 Oslo Universitetssykehus Hf Systems and methods for monitoring biological fluids
US20210003570A1 (en) 2017-05-10 2021-01-07 Rowan University Diagnostic biomarkers for detecting, subtyping, and/or assessing progression of multiple sclerosis
EP3630137B1 (en) 2017-05-22 2023-05-17 4D Pharma Research Limited Compositions comprising bacterial strains
TW201907931A (zh) 2017-05-24 2019-03-01 英商4D製藥研究有限公司 包含細菌菌株之組合物
CN111148762A (zh) 2017-05-31 2020-05-12 斯特库伯株式会社 免疫特异性结合至btn1a1的抗体和分子及其治疗性用途
CN111051346A (zh) 2017-05-31 2020-04-21 斯特库伯株式会社 使用免疫特异性结合btn1a1的抗体和分子治疗癌症的方法
KR20200026209A (ko) 2017-06-06 2020-03-10 주식회사 에스티큐브앤컴퍼니 Btn1a1 또는 btn1a1-리간드에 결합하는 항체 및 분자를 사용하여 암을 치료하는 방법
PL3638271T3 (pl) 2017-06-14 2021-03-22 4D Pharma Research Limited Kompozycje zawierające szczepy bakteryjne
SG11201912105PA (en) 2017-06-14 2020-01-30 4D Pharma Res Ltd Compositions comprising bacterial strains
HUE059249T2 (hu) 2017-06-14 2022-11-28 4D Pharma Res Limited Baktériumtörzseket tartalmazó készítmények
US12140592B2 (en) 2017-06-16 2024-11-12 Oklahoma Medical Research Foundation Biomarkers for assessing risk of transitioning to systemic lupus erythematosus classification and disease pathogenesis
US9784733B1 (en) 2017-06-22 2017-10-10 Dnt Scientific Research, Llc Rapid diagnostic test device by driven flow technology
JP7421218B2 (ja) 2017-07-21 2024-01-24 フンダシオ オスピタル ウニベルシタリ バル デブロン－インスティテュート デ レセルカ 子宮内膜癌のマーカとしてのａｇｒｉｎ
EP3655004A2 (en) 2017-07-21 2020-05-27 Novartis AG Compositions and methods to treat cancer
US9823244B1 (en) 2017-07-31 2017-11-21 Dnt Scientific Research, Llc Digital progressive compression driven flow cartridge for analyte detecting device and method
CA3070774A1 (en) 2017-08-25 2019-02-28 Five Prime Therapeutics, Inc. B7-h4 antibodies and methods of use thereof
CN110799546B (zh) 2017-09-01 2023-01-24 四川科伦博泰生物医药股份有限公司 重组双特异性抗体
JP7365704B2 (ja) 2017-09-05 2023-10-20 グラディエーター バイオサイエンシーズ インコーポレイテッド 幹細胞へのペイロードの送達
GB2581619A (en) 2017-09-15 2020-08-26 Univ California Inhibition of aminoacylase 3 (AA3) in the treatment of cancer
CN111868039A (zh) 2017-09-26 2020-10-30 加利福尼亚大学董事会 用于治疗癌症的组合物和方法
WO2019071054A1 (en) 2017-10-04 2019-04-11 The Broad Institute, Inc. METHODS AND COMPOSITIONS FOR MODIFYING THE FUNCTION AND STRUCTURE OF BUCKLES AND / OR CHROMATIN DOMAINS
SG11202002975YA (en) 2017-10-11 2020-04-29 Chemocentryx Inc Treatment of focal segmental glomerulosclerosis with ccr2 antagonists
US11525002B2 (en) 2017-10-11 2022-12-13 Board Of Regents, The University Of Texas System Human PD-L1 antibodies and methods of use therefor
JP2021500878A (ja) 2017-10-12 2021-01-14 ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム 免疫療法のためのｔ細胞受容体
EP3706795A4 (en) 2017-11-09 2021-10-13 Pinteon Therapeutics Inc. METHODS AND COMPOSITIONS FOR GENERATING AND USING HUMANIZED CONFORMATION SPECIFIC PHOSPHORYLATED TAU ANTIBODIES
CN109870581B (zh) 2017-12-04 2021-05-04 厦门万泰凯瑞生物技术有限公司 一种定量检测HBsAg的试剂盒及方法
US11714090B2 (en) 2017-12-15 2023-08-01 Syngenta Participations Ag Non-antibody ligands for detecting target proteins
WO2019156758A2 (en) 2018-01-05 2019-08-15 Vanderbilt University Antibody-mediated neutralization of chikungunya virus
CA3090102A1 (en) 2018-01-31 2019-08-08 Dovetail Genomics, Llc Sample prep for dna linkage recovery
WO2019155041A1 (en) 2018-02-12 2019-08-15 Vib Vzw Gβγ COMPLEX ANTIBODIES AND USES THEREOF
CA3091174A1 (en) 2018-02-21 2019-08-29 Five Prime Therapeutics, Inc. B7-h4 antibody formulations
WO2019165217A1 (en) 2018-02-22 2019-08-29 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Cd153 and/or cd30 in infection
EA202091810A1 (ru) 2018-03-02 2021-01-29 Файв Прайм Терапьютикс, Инк. Антитела к b7-h4 и способы их применения
EP4636403A3 (en) 2018-03-08 2025-12-24 Meso Scale Technologies, LLC Genetic marker and/or biomarkers for traumatic brain injury, and ultrasensitive assays for biomarkers of traumatic brain injury
CN112105644B (zh) 2018-03-23 2023-12-05 得克萨斯州大学系统董事会 针对人pd-l1和pd-l2的双重特异性抗体及其使用方法
EP3768726B1 (en) 2018-03-23 2024-10-30 Board of Regents, The University of Texas System Dual specificity antibodies to pd-l1 and pd-l2 and methods of use therefor
EP4063519B1 (en) 2018-04-09 2023-09-13 Advanced Cell Diagnostics, Inc. Methods to further enhance signal amplification for the in situ detection of nucleic acids
EP3785732A4 (en) 2018-04-24 2022-02-23 Ampsource Biopharma Shanghai Inc. Antibody against tim-3 and application thereof
US20210123016A1 (en) 2018-05-02 2021-04-29 Novartis Ag Regulators of human pluripotent stem cells and uses thereof
WO2019237119A1 (en) 2018-06-08 2019-12-12 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services New compositions and detection methods for onchocerca volvulus infection
WO2019244107A1 (en) 2018-06-21 2019-12-26 Daiichi Sankyo Company, Limited Compositions including cd3 antigen binding fragments and uses thereof
US11186651B2 (en) 2018-07-11 2021-11-30 The United States Of America As Represented By The Secretary, Department Of Health And Human Services Monoclonal antibody for the detection of the antiretroviral drug emtricitabine (FTC, 2′,3′-dideoxy-5-fluoro-3′-thiacytidine)
WO2020023417A1 (en) 2018-07-23 2020-01-30 Enclear Therapies, Inc. Methods of treating neurological disorders
AU2019310040A1 (en) 2018-07-23 2021-02-11 Enclear Therapies, Inc. Methods of treating neurological disorders
CA3109366A1 (en) 2018-09-13 2020-03-19 The Board Of Regents Of The University Of Texas System Novel lilrb4 antibodies and uses thereof
US12097239B2 (en) 2018-09-21 2024-09-24 President And Fellows Of Harvard College Methods and compositions for treating diabetes, and methods for enriching MRNA coding for secreted proteins
CN113195511A (zh) 2018-09-28 2021-07-30 生捷科技控股公司 二硫键连接的可逆终止剂
CA3116555A1 (en) 2018-10-15 2020-04-23 University Of Massachusetts Programmable dna base editing by nme2cas9-deaminase fusion proteins
EP3867645B1 (en) 2018-10-18 2024-06-05 Oklahoma Medical Research Foundation Biomarkers for a systemic lupus erythematosus (sle) disease activity immune index that characterizes disease activity
CN112912396B (zh) 2018-10-22 2023-03-14 上海吉倍生物技术有限公司 抗cldn18.2抗体及其用途
CA3115887A1 (en) 2018-10-23 2020-04-30 Glycardial Diagnostics, S.L. Antibodies specific for glycosylated apoj and uses thereof
CN112638419B (zh) 2018-11-02 2022-06-24 北京伟德杰生物科技有限公司 修饰的ctla4及其使用方法
US10451613B1 (en) 2018-11-09 2019-10-22 Dnt Scientific Research, Llc Rapid diagnostic test device and sampling method using driven flow technology
US20220026420A1 (en) 2018-11-16 2022-01-27 President And Fellows Of Harvard College Molecules and methods for improved immunodetection of small molecules such as histamine
CN111196851B (zh) 2018-11-20 2021-11-16 厦门万泰凯瑞生物技术有限公司 针对人抗缪勒管激素的特异性抗体及其应用
WO2020113084A1 (en) 2018-11-28 2020-06-04 Oregon Health & Science University Therapeutic factor xii antibody
EP4369356A3 (en) 2018-11-30 2024-07-24 Caris MPI, Inc. Next-generation molecular profiling
WO2020135201A1 (zh) 2018-12-28 2020-07-02 四川科伦博泰生物医药股份有限公司 一种抗体及其用途
WO2020185312A2 (en) 2019-01-25 2020-09-17 President And Fellows Of Harvard College Compositions and method for synthesizing nucleic acids
US11300576B2 (en) 2019-01-29 2022-04-12 Arizona Board Of Regents On Behalf Of Arizona State University DARPin reagents that distinguish Alzheimer's disease and Parkinson's disease samples
CN114555825A (zh) 2019-02-15 2022-05-27 领先细胞医疗诊断有限公司 用于通过原位杂交进行核酸的多路复用检测的方法
WO2020185763A1 (en) 2019-03-11 2020-09-17 Memorial Sloan Kettering Cancer Center Cd22 antibodies and methods of using the same
KR20220011123A (ko) 2019-04-11 2022-01-27 엔클리어 테라피스, 인크. 뇌척수액 개선 방법 및 이를 위한 디바이스 및 시스템
WO2020211674A1 (zh) 2019-04-16 2020-10-22 四川科伦博泰生物医药股份有限公司 抗FXI/FXIa抗体及其用途
KR20220015394A (ko) 2019-04-30 2022-02-08 라리마 테라퓨틱스, 인코포레이티드 프라탁신 대체 요법의 유효성 결정을 위한 프라탁신 민감성 마커
US11549943B2 (en) 2019-05-31 2023-01-10 International Business Machines Corporation Multiplexed lateral flow assay device
US11906515B2 (en) * 2019-05-31 2024-02-20 International Business Machines Corporation Multiplexed lateral flow assay device
WO2020245653A1 (en) 2019-06-04 2020-12-10 Alere Toxicology Plc Fluid specimen testing
DE102019117289A1 (de) 2019-06-27 2020-12-31 Katja Werner Trägermaterial, Kitsystem und Verfahren für biologische Assays
US20220267826A1 (en) 2019-06-27 2022-08-25 Dovetail Genomics, Llc Methods and compositions for proximity ligation
DE102019117413B4 (de) * 2019-06-27 2024-05-08 Testo SE & Co. KGaA Fließtest-Einheit, Set und Verwendung einer Fließtest-Einheit zur Durchführung einer Nachweisreaktion
AU2020314729B2 (en) 2019-07-16 2023-07-06 Meso Scale Technologies, Llc. Assay apparatuses, methods and reagents
US20220257653A1 (en) 2019-07-19 2022-08-18 The Children's Hospital Of Philadelphia Chimeric antigen receptors containing glypican 2 binding domains
KR20220038415A (ko) 2019-07-26 2022-03-28 벤더르빌트 유니버시티 엔테로바이러스 d68에 대한 인간 모노클로날 항체
WO2021055489A1 (en) 2019-09-16 2021-03-25 Grohar Patrick J Compositions and methods for the treatment of swi-snf mutant tumors
JP2023501871A (ja) 2019-09-20 2023-01-20 上海吉倍生物技術有限公司 Ｂｃｍａ標的化抗体及びキメラ抗原受容体
CN114729045B (zh) 2019-09-26 2025-09-09 斯特库比公司 对糖基化的ctla-4特异性的抗体及其使用方法
CN114206931B (zh) 2019-09-30 2024-06-04 四川科伦博泰生物医药股份有限公司 抗pd-1抗体及其用途
EP4041768A1 (en) 2019-10-09 2022-08-17 StCube & Co. Antibodies specific to glycosylated lag3 and methods of use thereof
CA3160211A1 (en) 2019-11-05 2021-05-14 Meso Scale Technologies, Llc. Methods and kits for quantitating radiation exposure
US10792360B1 (en) 2019-11-21 2020-10-06 Chemocentryx, Inc. Compositions and methods for treating inflammatory bowel disease using CCR9 inhibitor and anti-TNF-alpha blocking antibodies
US20230021837A1 (en) 2019-11-26 2023-01-26 Meso Scale Technologies, Llc. Methods and kits for detecting autoimmune diseases
CA3163319A1 (en) 2019-12-02 2021-06-10 Caris Mpi, Inc. Pan-cancer platinum response predictor
US20230029257A1 (en) 2019-12-12 2023-01-26 President And Fellows Of Harvard College Compositions and methods for light-directed biomolecular barcoding
MX2022004919A (es) 2019-12-13 2022-05-16 Sichuan Kelun Biotech Biopharmaceutical Co Ltd Anticuerpo anti-linfopoyetina estromal timica (tslp) y sus usos.
CA3164996A1 (en) 2019-12-20 2021-06-14 Novarock Biotherapeutics, Ltd. Anti-interleukin-23 p19 antibodies and methods of use thereof
EP3842452A1 (en) 2019-12-26 2021-06-30 Universitat Autònoma de Barcelona Scaffold proteins and therapeutic nanoconjugates based on nidogen
CN113061165A (zh) 2020-01-02 2021-07-02 厦门大学 EB病毒BNLF2b基因编码多肽及其检测用途
WO2021156490A2 (en) 2020-02-06 2021-08-12 Vib Vzw Corona virus binders
KR20220140568A (ko) 2020-02-11 2022-10-18 벤더르빌트 유니버시티 중증 급성 호흡기 증후군 코로나바이러스 2(SARS-CoV-2)에 대한 인간 단일클론 항체
WO2021167908A1 (en) 2020-02-17 2021-08-26 Board Of Regents, The University Of Texas System Methods for expansion of tumor infiltrating lymphocytes and use thereof
JP2023514654A (ja) 2020-02-25 2023-04-06 ブイアイビー ブイゼットダブリュ ロイシンリッチリピートキナーゼ２のアロステリック調節因子
MX2022011892A (es) 2020-03-26 2022-10-18 Univ Vanderbilt Anticuerpos monoclonales humanos dirigidos contra el coronavirus 2 del sindrome respiratorio agudo grave (sars-cov-2).
WO2021195385A1 (en) 2020-03-26 2021-09-30 Vanderbilt University HUMAN MONOCLONAL ANTIBODIES TO SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2 (SARS-GoV-2)
WO2021202731A1 (en) 2020-03-31 2021-10-07 Chemocentryx, Inc. Compositions and methods for treating inflammatory bowel disease using ccr9 inhibitor and anti-il-23 blocking antibodies
JP2023522958A (ja) 2020-04-22 2023-06-01 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ 核酸を検出するための等温法、組成物、キット、およびシステム
WO2021222832A1 (en) 2020-05-01 2021-11-04 Meso Scale Technologies, Llc. Viral serology ace2 competition assays
CA3178406A1 (en) 2020-05-15 2021-11-18 Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. Antibody drug conjugate, preparation method therefor and use thereof
EP3939999A1 (en) 2020-07-14 2022-01-19 Fundación del Sector Público Estatal Centro Nacional de Investigaciones Oncológicas Carlos III (F.S.P. CNIO) Interleukin 11 receptor alpha subunit (il11ra) neutralizing antibodies and uses thereof
US20230295698A1 (en) 2020-08-21 2023-09-21 Advanced Cell Diagnostics, Inc. Compositions and methods for determining t cell clonality
WO2022047359A1 (en) 2020-08-31 2022-03-03 Berg Llc Protein biomarkers for pancreatic cancer
CA3193584A1 (en) 2020-09-04 2022-03-10 Novarock Biotherapeutics, Ltd. Nectin-4 antibodies and uses thereof
AU2021355470A1 (en) 2020-09-29 2023-06-01 Enclear Therapies, Inc. Subarachnoid fluid management method and system
IL301950B2 (en) 2020-10-09 2025-09-01 Univ Texas Pre-stabilized hmpv f proteins
GB202105804D0 (en) 2020-11-20 2021-06-09 Univ Cape Town Use of microvirin in the identification of mycobacterium tuberculosis mannose-capped lipoarabinomannan
WO2022120064A1 (en) 2020-12-03 2022-06-09 The Board Of Regents Of The University Of Texas System Methods for identifying lilrb-blocking antibodies
JP2023553877A (ja) 2020-12-04 2023-12-26 ユニバーシティ オブ テネシー リサーチ ファウンデーション アミロイド疾患を診断する方法
WO2022143743A1 (zh) 2020-12-31 2022-07-07 和铂医药(苏州)有限公司 人lifr抗原结合蛋白及其制备方法和应用
GB2603166A (en) 2021-01-29 2022-08-03 Thelper As Therapeutic and Diagnostic Agents and Uses Thereof
TW202241521A (zh) 2021-02-09 2022-11-01 大陸商蘇州宜聯生物醫藥有限公司 生物活性物偶聯物及其製備方法和用途
WO2022175532A1 (en) 2021-02-19 2022-08-25 Vib Vzw Cation-independent mannose-6-phosphate receptor binders
US20240150455A1 (en) 2021-03-05 2024-05-09 Shanghai GenBase Biotechnology Co., Ltd. Anti-cldn6 antibody and use thereof
US20240165256A1 (en) 2021-03-08 2024-05-23 Immunogen, Inc. Methods for increasing efficacy of immunoconjugates targeting adam9 for the treatment of cancer
EP4306540A4 (en) 2021-03-09 2025-05-28 Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. ROR1-BINDING PROTEIN AND USE THEREOF
US20240230651A1 (en) 2021-04-06 2024-07-11 Bpgbio, Inc. Protein markers for the prognosis of breast cancer progression
WO2022216841A1 (en) 2021-04-06 2022-10-13 Berg Llc Protein markers for estrogen receptor (er)-positive luminal a(la)-like and luminal b1 (lb1)-like breast cancer
WO2022216846A1 (en) 2021-04-06 2022-10-13 Berg Llc Protein markers for estrogen receptor (er)-positive-like and estrogen receptor (er)-negative-like breast cancer
EP4322837A4 (en) 2021-04-16 2025-02-26 Advanced Cell Diagnostics, Inc. MATERIALS AND METHODS RELATED TO IMAGE PROCESSING
EP4327103A1 (en) 2021-04-19 2024-02-28 Temple Therapeutics BV Methods for detecting or treating endometrial and ovarian hyperproliferative disorders
WO2022246213A1 (en) 2021-05-21 2022-11-24 Meso Scale Techologies, Llc. Assays for viral strain determination
WO2023288046A1 (en) 2021-07-15 2023-01-19 President And Fellows Of Harvard College Compositions and methods relating to cells with adhered particles
EP4373973A1 (en) 2021-07-23 2024-05-29 Fundació Hospital Universitari Vall d'Hebron - Institut de Recerca Biomarkers for endometrial cancer
WO2023016828A2 (en) 2021-07-30 2023-02-16 Vib Vzw Cation-independent mannose-6-phosphate receptor binders for targeted protein degradation
CA3236778A1 (en) 2021-11-02 2023-05-11 Erik SONTHEIMER Nme2cas9 inlaid domain fusion proteins
IL312215A (en) 2021-11-19 2024-06-01 Mirobio Ltd PD-1 antibodies and their uses
US11833503B2 (en) 2021-12-07 2023-12-05 Insilixa, Inc. Methods and compositions for surface functionalization of optical semiconductor-integrated biochips
CA3243294A1 (en) 2022-01-25 2025-02-28 Medilink Therapeutics (Suzhou) Co., Ltd. Antibody against her3, conjugate, and use thereof
GB202201137D0 (en) 2022-01-28 2022-03-16 Thelper As Therapeutic and diagnostic agents and uses thereof
EP4238988A1 (en) 2022-03-01 2023-09-06 Consejo Superior De Investigaciones Científicas Antibodies against sars-cov-2 and uses thereof
CN114853890B (zh) 2022-03-16 2023-04-28 沈阳三生制药有限责任公司 一种prlr抗原结合蛋白及其制备方法和应用
AU2023243615A1 (en) 2022-04-01 2024-11-14 Board Of Regents, The University Of Texas System Dual specificity antibodies to human pd-l1 and pd-l2 and methods of use therefor
GB202204813D0 (en) 2022-04-01 2022-05-18 Bradcode Ltd Human monoclonal antibodies and methods of use thereof
US20230416361A1 (en) 2022-04-06 2023-12-28 Mirobio Limited Engineered cd200r antibodies and uses thereof
EP4505182A1 (en) 2022-04-06 2025-02-12 Larimar Therapeutics, Inc. Frataxin-sensitive markers for monitoring frataxin replacement therapy
WO2023240201A1 (en) 2022-06-08 2023-12-14 Larimar Therapeutics, Inc. Frataxin-sensitive markers for monitoring progression and treatment of leigh syndrome
CA3258660A1 (en) 2022-06-08 2023-12-14 Onkure, Inc. BENZOPYRIMIDIN-4 (3H)-ONES AS PI3K INHIBITORS
CN119546338A (zh) 2022-06-10 2025-02-28 研究发展基金会 经改造FcRIIB选择性IgG1 Fc变体及其用途
EP4540610A1 (en) 2022-06-17 2025-04-23 Meso Scale Technologies, LLC Viral strain serology assays
AU2023286928A1 (en) 2022-06-20 2025-01-02 Sichuan Huiyu Pharmaceutical Co., Ltd. Antibody and use thereof
JP2025523090A (ja) 2022-07-14 2025-07-17 メディリンク セラピューティクス（スーチョウ）カンパニー，リミティド 抗体薬物複合体及びその製造方法と使用
WO2024028794A1 (en) 2022-08-02 2024-02-08 Temple Therapeutics BV Methods for treating endometrial and ovarian hyperproliferative disorders
EP4573553A1 (en) 2022-08-15 2025-06-25 ABSCI Corporation Quantitative affinity activity specific cell enrichment
WO2024038160A1 (en) 2022-08-18 2024-02-22 Vib Vzw Means and methods to modulate neuron excitability
WO2024054469A1 (en) 2022-09-08 2024-03-14 Onkure, Inc. Isoquinolones as pi3k inhibitors
WO2024064024A1 (en) 2022-09-19 2024-03-28 Onkure, Inc. ((4-oxo-3,4-dihydroquinazolin-8-yl)methyl)amine derivatives as p13k inhibitors for the treatment of cancer
WO2024064002A1 (en) 2022-09-20 2024-03-28 Onkure, Inc. Hdac inhibitor oki-179 for the treatment of cancers resulting from a mapk pathway mutation
US20240103002A1 (en) 2022-09-23 2024-03-28 Meso Scale Technologies, Llc. Orthopoxvirus serology assays
EP4594348A1 (en) 2022-09-27 2025-08-06 Vib Vzw Antivirals against human parainfluenza virus
WO2024081345A1 (en) 2022-10-14 2024-04-18 Onkure, Inc. Benzopyrimidin-4(3h)-ones as pi3k inhibitors
EP4615490A2 (en) 2022-11-11 2025-09-17 IGAN Biosciences Iga protease polypeptide agents
WO2024124041A1 (en) 2022-12-07 2024-06-13 Advanced Cell Diagnostics, Inc. Multiplexed detection of nucleic acid targets
CN120569211A (zh) 2023-01-09 2025-08-29 得克萨斯州大学系统董事会 融合前稳定的人副流感病毒3f蛋白
WO2024178172A1 (en) 2023-02-23 2024-08-29 University Of Rochester Agents and methods for making closed-end dna thread molecules
WO2024213648A1 (en) 2023-04-11 2024-10-17 Sterling Ip Pte. Ltd. Treatment of haematological cancer
WO2024258743A1 (en) 2023-06-13 2024-12-19 Adcentrx Therapeutics, Inc. Methods and compositions related to antibodies and antibody drug conjugates (adcs) that bind nectin-4 proteins
WO2024261344A1 (en) 2023-06-23 2024-12-26 Vib Vzw Novel binders targeting the multi-drug resistant pathogen acinetobacter baumannii
WO2025038395A1 (en) 2023-08-11 2025-02-20 Onkure, Inc. Benzopyridinones and benzopyrimidinones as pi3k inhibitors
WO2025049305A1 (en) 2023-08-25 2025-03-06 Meso Scale Technologies, Llc. Viral strain serology assays
WO2025054524A1 (en) 2023-09-07 2025-03-13 University Of Tennessee Research Foundation Method for diagnosing amyloid diseases
WO2025125577A1 (en) 2023-12-14 2025-06-19 Vib Vzw Antibodies against influenza b virus
WO2025155991A2 (en) 2024-01-19 2025-07-24 Bpgbio, Inc. Predictive biomarkers for response to coenzyme q10 treatment in pancreatic cancer
WO2025202871A1 (en) 2024-03-27 2025-10-02 Pfizer Inc. Methods for identifying biomarkers of treatment response and use thereof with a cdk4 inhibitor
WO2025207755A1 (en) 2024-03-29 2025-10-02 Onkure, Inc. Quinolizinones as pi3k inhibitors
WO2025212360A1 (en) 2024-04-01 2025-10-09 Onkure, Inc. Isoquinolones as pi3k inhibitors
WO2025255233A1 (en) 2024-06-07 2025-12-11 Onkure, Inc. Compounds containing fused tricyclic rings as pi3k inhibitors

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3811840A (en) * 1969-04-01 1974-05-21 Miles Lab Test device for detecting low concentrations of substances in fluids
US4190496A (en) * 1971-05-14 1980-02-26 Syva Company Homogeneous enzyme assay for antibodies
IT1006557B (it) * 1971-09-08 1976-10-20 Bagshawe Kenneth Dawson Cella di reazione particolarmente utile in prove di radioimmunita
JPS4939720A (show.php) * 1972-08-26 1974-04-13
DE2436598C2 (de) * 1974-07-30 1983-04-07 Boehringer Mannheim Gmbh, 6800 Mannheim Stabiler Teststreifen zum Nachweis von Inhaltsstoffen in Flüssigkeiten
SE388694B (sv) * 1975-01-27 1976-10-11 Kabi Ab Sett att pavisa ett antigen exv i prov av kroppvetskor, med utnyttjande av till porost berarmaterial bundna eller adsorberande antikroppar
US4094647A (en) * 1976-07-02 1978-06-13 Thyroid Diagnostics, Inc. Test device
CA1095819A (en) * 1977-01-14 1981-02-17 Eastman Kodak Company Element for analysis of liquids
IL51354A (en) * 1977-01-28 1979-07-25 Ames Yissum Ltd Assay method for the quantitative determination of a hapten in aqueous solution
US4160008A (en) * 1978-01-26 1979-07-03 Miles Laboratories, Inc. Multilayered test device for determining the presence of a liquid sample component, and method of use
US4226978A (en) * 1978-03-13 1980-10-07 Miles Laboratories, Inc. β-Galactosyl-umbelliferone-labeled aminoglycoside antibiotics and intermediates in their preparation
AU531777B2 (en) * 1978-04-05 1983-09-08 Syva Co. Label/solid conjugate immunoassay system
US4233402A (en) * 1978-04-05 1980-11-11 Syva Company Reagents and method employing channeling
US4258001A (en) * 1978-12-27 1981-03-24 Eastman Kodak Company Element, structure and method for the analysis or transport of liquids
US4301139A (en) * 1979-06-21 1981-11-17 Ames-Yissum Ltd. Multilayer column chromatography specific binding assay method, test device and test kit
US4299916A (en) * 1979-12-26 1981-11-10 Syva Company Preferential signal production on a surface in immunoassays

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JP2505979B2 (ja) 1996-06-12
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US4366241A (en) 1982-12-28
CA1174595A (en) 1984-09-18
ATE10548T1 (de) 1984-12-15
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JPS5763454A (en) 1982-04-16
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EP0046004B1 (en) 1984-11-28

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