|
US7183387B1
(en)
|
1999-01-15 |
2007-02-27 |
Genentech, Inc. |
Polypeptide variants with altered effector function
|
|
US20050123925A1
(en)
|
2002-11-15 |
2005-06-09 |
Genentech, Inc. |
Compositions and methods for the diagnosis and treatment of tumor
|
|
MXPA04003798A
(es)
*
|
2001-10-25 |
2004-07-30 |
Genentech Inc |
Composiciones de glicoproteina.
|
|
US7696320B2
(en)
|
2004-08-24 |
2010-04-13 |
Domantis Limited |
Ligands that have binding specificity for VEGF and/or EGFR and methods of use therefor
|
|
AU2003287099A1
(en)
*
|
2002-11-08 |
2004-06-03 |
Kin-Ping Wong |
Extract of trapa natans and methods of using the same
|
|
US7758859B2
(en)
|
2003-08-01 |
2010-07-20 |
Genentech, Inc. |
Anti-VEGF antibodies
|
|
US20050106667A1
(en)
|
2003-08-01 |
2005-05-19 |
Genentech, Inc |
Binding polypeptides with restricted diversity sequences
|
|
EP2361931B1
(en)
|
2004-07-20 |
2017-12-06 |
Genentech, Inc. |
Inhibitors of angiopoietin-like 4 protein, combinations, and their use
|
|
US8604185B2
(en)
|
2004-07-20 |
2013-12-10 |
Genentech, Inc. |
Inhibitors of angiopoietin-like 4 protein, combinations, and their use
|
|
KR20070086218A
(ko)
*
|
2004-12-17 |
2007-08-27 |
제넨테크, 인크. |
자가면역 질환에 대한 이전 요법에 실패했던 환자에서의,자가면역 질환의 항-혈관신생 요법
|
|
FR2893622B1
(fr)
|
2005-11-24 |
2007-12-21 |
Commissariat Energie Atomique |
Composition a base de caprolactame,procede de fabrication d'un element d'etancheite,et reservoir
|
|
KR101434682B1
(ko)
*
|
2005-12-02 |
2014-08-27 |
제넨테크, 인크. |
결합 폴리펩티드 및 이들의 용도
|
|
CN101370832B
(zh)
*
|
2005-12-02 |
2014-07-02 |
健泰科生物技术公司 |
结合多肽及其用途
|
|
AU2012204022C1
(en)
*
|
2005-12-02 |
2014-02-20 |
Genentech, Inc. |
Binding polypeptides and uses thereof
|
|
WO2007064919A2
(en)
*
|
2005-12-02 |
2007-06-07 |
Genentech, Inc. |
Binding polypeptides with restricted diversity sequences
|
|
US20100056439A1
(en)
*
|
2005-12-06 |
2010-03-04 |
Domantis Limited |
Ligands that have binding specificity for egfr and/or vegf and methods of use therefor
|
|
EP1973948B1
(en)
|
2005-12-15 |
2015-02-11 |
Genentech, Inc. |
Methods and compositions for targeting polyubiquitin
|
|
TWI596111B
(zh)
|
2006-01-05 |
2017-08-21 |
建南德克公司 |
抗ｅｐｈｂ４抗體及使用該抗體之方法
|
|
US8168181B2
(en)
|
2006-02-13 |
2012-05-01 |
Alethia Biotherapeutics, Inc. |
Methods of impairing osteoclast differentiation using antibodies that bind siglec-15
|
|
DK1994155T4
(da)
*
|
2006-02-13 |
2022-07-25 |
Daiichi Sankyo Co Ltd |
Polynukleotid- og polypeptidsekvenser involveret i fremgangsmåden med knogleremodellering
|
|
AR059851A1
(es)
|
2006-03-16 |
2008-04-30 |
Genentech Inc |
Anticuerpos de la egfl7 y metodos de uso
|
|
JP5298007B2
(ja)
|
2006-03-21 |
2013-09-25 |
ジェネンテック， インコーポレイテッド |
アルファ５ベータ１アンタゴニストを含むコンビナトリアル療法
|
|
WO2007139359A1
(en)
*
|
2006-05-31 |
2007-12-06 |
Hanwha Chemical Corporation |
Vcam-1 specific monoclonal antibody
|
|
RU2415869C2
(ru)
*
|
2006-06-06 |
2011-04-10 |
Дженентек, Инк. |
Антитела против dll4 и способы их применения
|
|
JP2009539384A
(ja)
*
|
2006-06-06 |
2009-11-19 |
ジェネンテック・インコーポレーテッド |
抗ｄｌｌ４抗体および抗ｄｌｌ４抗体使用の方法
|
|
US20080050385A1
(en)
*
|
2006-08-21 |
2008-02-28 |
Thomas Friess |
Tumor therapy with an anti-vegf antibody
|
|
DK2059533T3
(da)
*
|
2006-08-30 |
2013-02-25 |
Genentech Inc |
Multispecifikke antistoffer
|
|
PL2066694T3
(pl)
|
2006-09-29 |
2016-04-29 |
Oncomed Pharm Inc |
Kompozycje i sposoby diagnozowania i leczenia nowotworu
|
|
EP2415783B1
(en)
|
2006-10-16 |
2016-12-14 |
Genelux Corporation |
Modified vaccinia virus strains for use in a diagnostic and therapeutic method
|
|
CU23636A1
(es)
|
2006-11-01 |
2011-03-21 |
Ct Ingenieria Genetica Biotech |
Anticuerpos recombinantes contra el factor de crecimiento del endotelio vascular (vegf)
|
|
JP2010512407A
(ja)
*
|
2006-12-11 |
2010-04-22 |
ジェネンテック インコーポレイテッド |
新生物を処置するための組成物および方法
|
|
CN103143017A
(zh)
*
|
2006-12-19 |
2013-06-12 |
基因技术公司 |
用于辅助和新辅助疗法以及早期肿瘤的治疗的vegf特异性拮抗剂
|
|
BRPI0806414A2
(pt)
*
|
2007-02-01 |
2011-09-06 |
Genentech Inc |
método para tratamento de tumor
|
|
BRPI0806403A2
(pt)
|
2007-02-09 |
2011-09-06 |
Genentech Inc |
anticorpo anti-robo4, usode um anticorpo e método de obtenção de imagem
|
|
NZ579010A
(en)
*
|
2007-02-20 |
2012-03-30 |
Anaptysbio Inc |
Somatic hypermutation systems
|
|
US8642067B2
(en)
|
2007-04-02 |
2014-02-04 |
Allergen, Inc. |
Methods and compositions for intraocular administration to treat ocular conditions
|
|
US7977313B2
(en)
*
|
2007-04-27 |
2011-07-12 |
Affinergy, Inc. |
Methods and compositions for promoting localization of pharmaceutically active agents to bone
|
|
GB0709333D0
(en)
|
2007-05-15 |
2007-06-20 |
Smart Targeting Ltd |
Binding protein
|
|
MX2009012282A
(es)
*
|
2007-05-17 |
2009-11-25 |
Genentech Inc |
Estructuras cristalinas de fragmentos de neuropilina y complejos de neuropilina-anticuerpos.
|
|
PE20090321A1
(es)
|
2007-06-04 |
2009-04-20 |
Genentech Inc |
Anticuerpos anti-notch1 nrr, metodo de preparacion y composicion farmaceutica
|
|
US20090011060A1
(en)
*
|
2007-07-06 |
2009-01-08 |
Peter Koepke |
Campsiandra angustifolia extract and methods of extracting and using such extract
|
|
US7879369B2
(en)
|
2007-09-18 |
2011-02-01 |
Selvamedica, Llc |
Combretum laurifolium Mart. extract and methods of extracting and using such extract
|
|
DK2219672T3
(en)
|
2007-11-09 |
2016-05-17 |
Peregrine Pharmaceuticals Inc |
The anti-VEGF antibody compositions and methods
|
|
CA2703099A1
(en)
|
2007-11-09 |
2009-05-14 |
Genentech, Inc. |
Activin receptor-like kinase-i compositions and methods of use
|
|
AU2013205269B2
(en)
*
|
2007-11-09 |
2016-05-19 |
Affitech Research As |
Anti-VEGF antibody compositions and methods
|
|
AU2015200714B2
(en)
*
|
2007-11-30 |
2017-01-12 |
Genentech, Inc. |
Anti-VEGF antibodies
|
|
AU2013204108B2
(en)
*
|
2007-11-30 |
2014-11-20 |
Genentech, Inc. |
Anti-VEGF antibodies
|
|
AR069501A1
(es)
*
|
2007-11-30 |
2010-01-27 |
Genentech Inc |
Anticuerpos anti- vegf (factor de crecimiento endotelial vascular)
|
|
US9266967B2
(en)
|
2007-12-21 |
2016-02-23 |
Hoffmann-La Roche, Inc. |
Bivalent, bispecific antibodies
|
|
US8227577B2
(en)
*
|
2007-12-21 |
2012-07-24 |
Hoffman-La Roche Inc. |
Bivalent, bispecific antibodies
|
|
US20090162359A1
(en)
|
2007-12-21 |
2009-06-25 |
Christian Klein |
Bivalent, bispecific antibodies
|
|
CA2710398A1
(en)
|
2008-01-18 |
2009-10-15 |
Genentech, Inc. |
Methods and compositions for targeting polyubiquitin
|
|
SI2644204T1
(sl)
|
2008-03-18 |
2017-08-31 |
Genentech, Inc. |
Kombinacije konjugata protitelo proti HER2-zdravilo in pertuzumaba
|
|
PL2274008T3
(pl)
|
2008-03-27 |
2014-07-31 |
Zymogenetics Inc |
Kompozycje i sposoby hamowania PDGFRbeta i VEGF-A
|
|
NZ588554A
(en)
*
|
2008-04-29 |
2013-03-28 |
Abbott Lab |
Dual variable domain immunoglobulins and uses thereof
|
|
SG191625A1
(en)
|
2008-06-03 |
2013-07-31 |
Abbott Lab |
Dual variable domain immunoglobulins and uses thereof
|
|
AU2009256250B2
(en)
|
2008-06-03 |
2013-05-30 |
Abbvie Inc. |
Dual variable domain immunoglobulins and uses thereof
|
|
HRP20241467T1
(hr)
|
2008-06-25 |
2025-01-03 |
Novartis Ag |
Stabilna i topljiva protutijela koja inhibiraju vegf
|
|
KR20110044992A
(ko)
*
|
2008-07-02 |
2011-05-03 |
이머전트 프로덕트 디벨롭먼트 시애틀, 엘엘씨 |
ＴＧＦ-β 길항제 다중-표적 결합 단백질
|
|
SG192489A1
(en)
|
2008-07-08 |
2013-08-30 |
Abbott Lab |
Prostaglandin e2 dual variable domain immunoglobulins and uses thereof
|
|
US20100029491A1
(en)
*
|
2008-07-11 |
2010-02-04 |
Maike Schmidt |
Methods and compositions for diagnostic use for tumor treatment
|
|
WO2010025414A2
(en)
*
|
2008-08-29 |
2010-03-04 |
Genentech, Inc. |
Diagnostics and treatments for vegf-independent tumors
|
|
US8268314B2
(en)
*
|
2008-10-08 |
2012-09-18 |
Hoffmann-La Roche Inc. |
Bispecific anti-VEGF/anti-ANG-2 antibodies
|
|
PE20150682A1
(es)
|
2008-10-14 |
2015-05-20 |
Genentech Inc |
Variantes de inmunoglobulinas y sus usos
|
|
WO2010056893A1
(en)
*
|
2008-11-13 |
2010-05-20 |
Imclone Llc |
Humanization and affinity-optimization of antibodies
|
|
AR074203A1
(es)
*
|
2008-11-22 |
2010-12-29 |
Genentech Inc |
Terapia anti-angiogenesis para el tratamiento del cancer de mama. kit. uso.
|
|
MX2011006875A
(es)
|
2008-12-23 |
2011-07-20 |
Genentech Inc |
Metodos y composiciones para uso en diagnostico de pacientes con cancer.
|
|
CN103755808B
(zh)
|
2009-03-25 |
2016-02-10 |
霍夫曼-拉罗奇有限公司 |
抗-α5β1抗体及其应用
|
|
BRPI1014089A2
(pt)
*
|
2009-04-02 |
2016-04-19 |
Roche Glycart Ag |
anticorpos multiespecíficos que compreendem anticorpos de comprimento completo e fragmentos fab de cadeia simples
|
|
ES2537100T3
(es)
|
2009-04-07 |
2015-06-02 |
Roche Glycart Ag |
Anticuerpos biespecíficos trivalentes
|
|
AU2010239368A1
(en)
*
|
2009-04-20 |
2011-11-10 |
Genentech, Inc. |
Adjuvant cancer therapy
|
|
BRPI1014262A2
(pt)
|
2009-04-20 |
2017-05-23 |
Oxford Biotherapeutics Ltd |
anticorpos específicos para caderina-17
|
|
US9676845B2
(en)
|
2009-06-16 |
2017-06-13 |
Hoffmann-La Roche, Inc. |
Bispecific antigen binding proteins
|
|
BR112012000735A2
(pt)
|
2009-07-13 |
2016-11-16 |
Genentech Inc |
"métodos, kits e conjuntos de compostos"
|
|
WO2011014457A1
(en)
|
2009-07-27 |
2011-02-03 |
Genentech, Inc. |
Combination treatments
|
|
SG178177A1
(en)
|
2009-07-31 |
2012-03-29 |
Genentech Inc |
Inhibition of tumor metastasis using bv8- or g-csf-antagonists
|
|
CA2770825A1
(en)
|
2009-08-13 |
2011-02-17 |
Crystal Bioscience Inc. |
Transgenic animal for production of antibodies having minimal cdrs
|
|
MX2012001716A
(es)
|
2009-08-14 |
2012-04-02 |
Genentech Inc |
Marcadores biologicos para monitorizar la respuesta del paciente a los antagonistas vegf.
|
|
BR112012003346A2
(pt)
|
2009-08-15 |
2016-11-16 |
Genentech Inc |
metodo de tratamento de um paciente diagnostico com cancer de mama metastico previamente tratado kit para tratamento de cancer de mama metastatico previamente tratado em um paciente humano metodo para instruir um paciente humano com cancer metodo promocional e metodo comercial
|
|
CN102612524A
(zh)
|
2009-09-01 |
2012-07-25 |
雅培制药有限公司 |
双重可变结构域免疫球蛋白及其用途
|
|
SG179070A1
(en)
|
2009-09-11 |
2012-04-27 |
Genentech Inc |
Method to identify a patient with an increased likelihood of responding to an anti-cancer agent
|
|
NZ598962A
(en)
|
2009-09-16 |
2014-12-24 |
Genentech Inc |
Coiled coil and/or tether containing protein complexes and uses thereof
|
|
JP5606537B2
(ja)
|
2009-09-17 |
2014-10-15 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
癌患者における診断使用のための方法及び組成物
|
|
WO2011044133A2
(en)
*
|
2009-10-05 |
2011-04-14 |
Opsonic Therapeutics Inc. |
High affinity adaptor molecules for redirecting antibody specifity
|
|
PH12012500691A1
(en)
|
2009-10-15 |
2012-11-12 |
Abbott Lab |
Dual variable domain immunoglobulins and uses thereof
|
|
WO2011047383A1
(en)
|
2009-10-16 |
2011-04-21 |
Oncomed Pharmaceuticals, Inc. |
Therapeutic combination and methods of treatment with a dll4 antagonist and an anti-hypertensive agent
|
|
LT2491134T
(lt)
*
|
2009-10-21 |
2017-10-10 |
Genentech, Inc. |
Genetiniai polimorfizmai, esant geltonosios dėmės su amžiumi susietai degeneracijai
|
|
WO2011056502A1
(en)
|
2009-10-26 |
2011-05-12 |
Genentech, Inc. |
Bone morphogenetic protein receptor type ii compositions and methods of use
|
|
WO2011056497A1
(en)
|
2009-10-26 |
2011-05-12 |
Genentech, Inc. |
Activin receptor type iib compositions and methods of use
|
|
UY32979A
(es)
|
2009-10-28 |
2011-02-28 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
|
CN102770456B
(zh)
*
|
2009-12-04 |
2018-04-06 |
弗·哈夫曼-拉罗切有限公司 |
多特异性抗体、抗体类似物、组合物和方法
|
|
WO2011071577A1
(en)
|
2009-12-11 |
2011-06-16 |
Genentech, Inc. |
Anti-vegf-c antibodies and methods using same
|
|
US8765432B2
(en)
|
2009-12-18 |
2014-07-01 |
Oligasis, Llc |
Targeted drug phosphorylcholine polymer conjugates
|
|
EP3616719A1
(en)
|
2009-12-21 |
2020-03-04 |
F. Hoffmann-La Roche AG |
Antibody formulation
|
|
AR079704A1
(es)
|
2009-12-23 |
2012-02-15 |
Genentech Inc |
Anticuerpos anti-bv8 y sus usos
|
|
US20110171231A1
(en)
*
|
2010-01-12 |
2011-07-14 |
Carlos Bais |
ANTI-PlGF ANTIBODIES AND METHODS USING SAME
|
|
US8778340B2
(en)
|
2010-02-23 |
2014-07-15 |
Genentech, Inc. |
Anti-angiogenesis therapy for the treatment of ovarian cancer
|
|
CN102167740B
(zh)
*
|
2010-02-25 |
2014-06-04 |
上海百迈博制药有限公司 |
一种全人源抗vegf单克隆抗体、其制备方法及用途
|
|
TW201138821A
(en)
|
2010-03-26 |
2011-11-16 |
Roche Glycart Ag |
Bispecific antibodies
|
|
AR080794A1
(es)
*
|
2010-03-26 |
2012-05-09 |
Hoffmann La Roche |
Anticuerpos bivalentes biespecificos anti- vegf/ anti-ang-2
|
|
MX336323B
(es)
|
2010-04-15 |
2016-01-15 |
Genentech Inc |
Anticuerpos de anti-poliubiquitina y metodos de uso.
|
|
WO2011153243A2
(en)
|
2010-06-02 |
2011-12-08 |
Genentech, Inc. |
Anti-angiogenesis therapy for treating gastric cancer
|
|
WO2011153224A2
(en)
|
2010-06-02 |
2011-12-08 |
Genentech, Inc. |
Diagnostic methods and compositions for treatment of cancer
|
|
NZ604464A
(en)
|
2010-06-14 |
2014-03-28 |
Vaccinex Inc |
Anti-vegf antibodies and uses thereof
|
|
RU2013104039A
(ru)
|
2010-07-19 |
2014-08-27 |
Ф. Хоффманн-Ля Рош Аг |
Способ идентификации пациента с повышенной вероятностью ответа на противораковую терапию
|
|
BR112013001429A2
(pt)
|
2010-07-19 |
2016-05-31 |
Hoffmann La Roche |
método de identificação de pacientes com maior probabilidade de responder a terapia anticâncer
|
|
AU2011280969A1
(en)
|
2010-07-23 |
2013-02-07 |
Trustees Of Boston University |
Anti-Despr inhibitors as therapeutics for inhibition of pathological angiogenesis and tumor cell invasiveness and for molecular imaging and targeted delivery
|
|
MX341579B
(es)
|
2010-08-03 |
2016-08-25 |
Abbvie Inc * |
Inmunoglobulinas de dominio variable doble y usos de las mismas.
|
|
AR082693A1
(es)
|
2010-08-17 |
2012-12-26 |
Roche Glycart Ag |
Terapia de combinacion de un anticuerpo anti-cd20 afucosilado con un anticuerpo anti-vegf
|
|
RU2013110875A
(ru)
|
2010-08-24 |
2014-09-27 |
Ф.Хоффманн-Ля Рош Аг |
БИСПЕЦИФИЧЕСКИЕ АНТИТЕЛА, СОДЕРЖАЩИЕ СТАБИЛИЗИРОВАННЫЙ ДИСУЛЬФИДОМ ФРАГМЕНТ Fv
|
|
TW201211252A
(en)
|
2010-08-26 |
2012-03-16 |
Abbott Lab |
Dual variable domain immunoglobulins and uses thereof
|
|
WO2012031027A1
(en)
|
2010-08-31 |
2012-03-08 |
Genentech, Inc. |
Biomarkers and methods of treatment
|
|
US8551479B2
(en)
|
2010-09-10 |
2013-10-08 |
Oncomed Pharmaceuticals, Inc. |
Methods for treating melanoma
|
|
EP2629796A4
(en)
*
|
2010-10-20 |
2015-01-28 |
Oxford Biotherapeutics Ltd |
ANTIBODY
|
|
MX346500B
(es)
*
|
2010-11-10 |
2017-03-22 |
Genentech Inc * |
Metodos y composiciones para inmunoterapia para enfermedad neural.
|
|
WO2012068032A1
(en)
|
2010-11-15 |
2012-05-24 |
Five Prime Therapeutics, Inc. |
Fgfr1 extracellular domain combination therapies
|
|
BR112013013003A2
(pt)
*
|
2010-11-24 |
2016-08-09 |
Glaxo Group Ltd |
proteína de ligação de antígeno, e, composição farmacêutica
|
|
EP2655413B1
(en)
|
2010-12-23 |
2019-01-16 |
F.Hoffmann-La Roche Ag |
Polypeptide-polynucleotide-complex and its use in targeted effector moiety delivery
|
|
CU23895B1
(es)
|
2010-12-28 |
2013-05-31 |
Biorec Sa |
Anticuerpos recombinantes contra el factor de crecimiento del endotelio vascular (vegf) obtenidos mediante mutagénesis de regiones variables
|
|
WO2012092539A2
(en)
|
2010-12-31 |
2012-07-05 |
Takeda Pharmaceutical Company Limited |
Antibodies to dll4 and uses thereof
|
|
EP3252076B1
(en)
|
2011-01-14 |
2019-09-04 |
The Regents Of The University Of California |
Diagnostic use of antibodies against ror-1 protein
|
|
CN103492562B
(zh)
*
|
2011-02-03 |
2017-04-05 |
佐马技术有限公司 |
用于增强细菌中功能蛋白表达的方法和材料
|
|
CN103403025B
(zh)
|
2011-02-28 |
2016-10-12 |
弗·哈夫曼-拉罗切有限公司 |
单价抗原结合蛋白
|
|
RU2607038C2
(ru)
|
2011-02-28 |
2017-01-10 |
Ф. Хоффманн-Ля Рош Аг |
Антигенсвязывающие белки
|
|
HRP20181690T4
(hr)
|
2011-03-29 |
2025-01-03 |
Roche Glycart Ag |
Varijante protutijela fc
|
|
SG194045A1
(en)
|
2011-04-01 |
2013-11-29 |
Genentech Inc |
Combinations of akt inhibitor compounds and abiraterone, and methods of use
|
|
CA2833747C
(en)
|
2011-04-20 |
2022-10-18 |
Asya Grinberg |
Endoglin polypeptides and uses thereof
|
|
CA2834776A1
(en)
|
2011-05-03 |
2012-11-08 |
Genentech, Inc. |
Therapeutic apo2l/trail polypeptides and death receptor agonist antibodies
|
|
JP2014522843A
(ja)
|
2011-06-30 |
2014-09-08 |
ジェネンテック， インコーポレイテッド |
抗ｃ−ｍｅｔ抗体製剤
|
|
US20130022551A1
(en)
|
2011-07-22 |
2013-01-24 |
Trustees Of Boston University |
DEspR ANTAGONISTS AND AGONISTS AS THERAPEUTICS
|
|
WO2013019491A1
(en)
|
2011-08-01 |
2013-02-07 |
Denovo Sciences |
Cell capture system and method of use
|
|
US10466160B2
(en)
|
2011-08-01 |
2019-11-05 |
Celsee Diagnostics, Inc. |
System and method for retrieving and analyzing particles
|
|
CN104011078B
(zh)
|
2011-08-05 |
2016-11-09 |
健泰科生物技术公司 |
抗聚泛素抗体及使用方法
|
|
EP2744825A1
(en)
|
2011-08-17 |
2014-06-25 |
F.Hoffmann-La Roche Ag |
Inhibition of angiogenesis in refractory tumors
|
|
RU2014114617A
(ru)
|
2011-09-19 |
2015-10-27 |
Дженентек, Инк. |
Комбинированные виды лечения, содержащие антагонисты с-мет и антагонисты b-raf
|
|
HRP20230078T1
(hr)
|
2011-09-23 |
2023-05-12 |
Mereo Biopharma 5, Inc. |
Sredstva za vezivanje vegf/dll4 i njihova uporaba
|
|
EP2782932A1
(en)
|
2011-11-21 |
2014-10-01 |
F.Hoffmann-La Roche Ag |
Purification of anti-c-met antibodies
|
|
WO2013082511A1
(en)
|
2011-12-02 |
2013-06-06 |
Genentech, Inc. |
Methods for overcoming tumor resistance to vegf antagonists
|
|
AU2012348600A1
(en)
|
2011-12-05 |
2014-05-22 |
F. Hoffmann-La Roche Ag |
Blood plasma biomarkers for bevacizumab combination therapies for treatment of breast cancer
|
|
US20130195851A1
(en)
|
2011-12-23 |
2013-08-01 |
Genentech, Inc. |
Articles of manufacture and methods for co-administration of antibodies
|
|
BR112014015851A2
(pt)
|
2011-12-30 |
2019-09-24 |
Abbvie Inc |
proteínas de ligação específicas duplas direcionadas contra il-13 e/ou il-17
|
|
BR112014017320A2
(en)
|
2012-01-13 |
2018-05-29 |
Genentech, Inc |
method for determining whether a patient is prone to respond to treatment with a vegf antagonist, method for optimizing the therapeutic efficacy of a vegf antagonist, method for selecting a therapy, method for identifying a biomarker, and method for diagnosing an angiogenic disorder
|
|
MX2014009565A
(es)
|
2012-02-10 |
2014-11-10 |
Genentech Inc |
Anticuerpos monocatenarios y otros heteromultimeros.
|
|
CA3056813A1
(en)
|
2012-03-13 |
2013-09-19 |
F. Hoffmann-La Roche Ag |
Combination therapy for the treatment of ovarian cancer
|
|
SG11201406184XA
(en)
|
2012-03-30 |
2014-10-30 |
Genentech Inc |
Diagnostic methods and compositions for treatment of cancer
|
|
WO2013152252A1
(en)
|
2012-04-06 |
2013-10-10 |
OSI Pharmaceuticals, LLC |
Combination anti-cancer therapy
|
|
TW201823460A
(zh)
*
|
2012-05-29 |
2018-07-01 |
美商再生元醫藥公司 |
生產細胞株增強子
|
|
SG10201603055WA
(en)
|
2012-05-31 |
2016-05-30 |
Genentech Inc |
Methods Of Treating Cancer Using PD-L1 Axis Binding Antagonists And VEGF Antagonists
|
|
CN109939236A
(zh)
|
2012-06-08 |
2019-06-28 |
豪夫迈·罗氏有限公司 |
用于治疗癌症的磷酸肌醇3激酶抑制剂化合物和化疗剂的突变选择性及组合
|
|
EP2861064A4
(en)
*
|
2012-06-11 |
2015-12-02 |
Syngenta Participations Ag |
MANUFACTURE OF SOLIDS AND ASSOCIATED MOTHER TUBES
|
|
MX2014014821A
(es)
|
2012-06-26 |
2015-02-12 |
Hoffmann La Roche |
Biomarcadores de plasma sanguineo para terapias de combinacion con bevacizumab para el tratamiento de cancer de mama.
|
|
MX354862B
(es)
|
2012-06-27 |
2018-03-23 |
Hoffmann La Roche |
Método para la producción de entidades dirigidas altamente selectivas hechas a la medida y biespecíficas que contienen dos entidades de unión diferentes.
|
|
BR112014028368A2
(pt)
|
2012-06-27 |
2017-11-14 |
Hoffmann La Roche |
método de produção de conjugado de região fc de anticorpo, conjugado de região fc de anticorpo e formulação farmacêutica
|
|
RS62509B1
(sr)
|
2012-07-13 |
2021-11-30 |
Roche Glycart Ag |
Bispecifična anti-vegf/anti-ang-2 antitela i njihova upotreba u lečenju očnih vaskularnih bolesti
|
|
CN104507969A
(zh)
|
2012-07-19 |
2015-04-08 |
阿莱斯亚生物疗法股份有限公司 |
抗siglec-15抗体
|
|
JP6464085B2
(ja)
|
2012-08-07 |
2019-02-06 |
ジェネンテック， インコーポレイテッド |
神経膠芽腫の治療のための併用療法
|
|
KR20200143502A
(ko)
*
|
2012-08-13 |
2020-12-23 |
제넨테크, 인크. |
항-jagged 항체 및 사용 방법
|
|
US12024568B2
(en)
|
2012-09-13 |
2024-07-02 |
Cornell University |
Treatment of brain cancers using central nervous system mediated gene transfer of monoclonal antibodies
|
|
JP6371294B2
(ja)
|
2012-10-31 |
2018-08-08 |
オンコメッド ファーマシューティカルズ インコーポレイテッド |
Ｄｌｌ４アンタゴニストによる処置の方法およびモニタリング
|
|
PE20151179A1
(es)
|
2012-11-01 |
2015-09-12 |
Abbvie Inc |
Inmunoglobulinas de dominio variable dual anti-vegf/dll4 y usos de las mismas
|
|
US20140154255A1
(en)
*
|
2012-11-30 |
2014-06-05 |
Abbvie Biotherapeutics Inc. |
Anti-vegf antibodies and their uses
|
|
US10138519B2
(en)
*
|
2012-12-28 |
2018-11-27 |
Quest Diagnostics Investments Incorporated |
Universal sanger sequencing from next-gen sequencing amplicons
|
|
MX368730B
(es)
|
2013-02-18 |
2019-10-14 |
Vegenics Pty Ltd |
Moleculas que unen ligando y usos de las mismas.
|
|
KR20150118159A
(ko)
|
2013-02-22 |
2015-10-21 |
에프. 호프만-라 로슈 아게 |
암의 치료 방법 및 약물 내성의 예방 방법
|
|
MX2015011428A
(es)
|
2013-03-06 |
2016-02-03 |
Genentech Inc |
Metodos para tratar y prevenir la resistencia a los farmacos para el cancer.
|
|
AU2014243783B2
(en)
|
2013-03-13 |
2018-12-13 |
Genentech, Inc. |
Antibody formulations
|
|
RU2015139054A
(ru)
|
2013-03-14 |
2017-04-19 |
Дженентек, Инк. |
Способы лечения рака и профилактики лекарственной резистентности рака
|
|
JP2016522793A
(ja)
|
2013-03-15 |
2016-08-04 |
アッヴィ・インコーポレイテッド |
ＩＬ−１βおよび／またはＩＬ−１７に対して指向された二重特異的結合タンパク質
|
|
KR20150130451A
(ko)
|
2013-03-15 |
2015-11-23 |
제넨테크, 인크. |
암 치료 방법 및 항암제 내성 예방을 위한 방법
|
|
SG11201508358RA
(en)
|
2013-04-09 |
2015-11-27 |
Boston Biomedical Inc |
2-acetylnaphtho[2,3-b]furan -4,9-dione for use on treating cancer
|
|
EP2999799A4
(en)
|
2013-05-23 |
2016-12-28 |
Five Prime Therapeutics Inc |
METHOD FOR TREATING CARCINOMA
|
|
US10391490B2
(en)
|
2013-05-31 |
2019-08-27 |
Celsee Diagnostics, Inc. |
System and method for isolating and analyzing cells
|
|
KR101541478B1
(ko)
|
2013-05-31 |
2015-08-05 |
동아쏘시오홀딩스 주식회사 |
항-vegf 항체 및 이를 포함하는 암 또는 신생혈관형성관련 질환의 예방, 진단 또는 치료용 약학 조성물
|
|
US10093978B2
(en)
|
2013-08-12 |
2018-10-09 |
Genentech, Inc. |
Compositions for detecting complement factor H (CFH) and complement factor I (CFI) polymorphisms
|
|
US10617755B2
(en)
|
2013-08-30 |
2020-04-14 |
Genentech, Inc. |
Combination therapy for the treatment of glioblastoma
|
|
US10456470B2
(en)
|
2013-08-30 |
2019-10-29 |
Genentech, Inc. |
Diagnostic methods and compositions for treatment of glioblastoma
|
|
JP6463361B2
(ja)
|
2013-09-08 |
2019-01-30 |
コディアック サイエンシーズ インコーポレイテッドＫｏｄｉａｋ Ｓｃｉｅｎｃｅｓ Ｉｎｃ． |
第ｖｉｉｉ因子両性イオンポリマーコンジュゲート
|
|
RU2016115866A
(ru)
|
2013-10-11 |
2017-11-16 |
Ф. Хоффманн-Ля Рош Аг |
Мультиспецифические антитела с обменянными доменами и одинаковыми вариабельными доменами легкой цепи
|
|
EP3060235B1
(en)
|
2013-10-25 |
2020-12-02 |
Acceleron Pharma Inc. |
Endoglin peptides to treat fibrotic diseases
|
|
US10294295B2
(en)
|
2013-11-27 |
2019-05-21 |
Inis Biotech Llc |
Methods for modulating angiogenesis of cancers refractory to anti-VEGF treatment
|
|
EP3080611B1
(en)
|
2013-12-13 |
2018-11-14 |
The General Hospital Corporation |
Soluble high molecular weight (hmw) tau species and applications thereof
|
|
MX2015014724A
(es)
*
|
2013-12-31 |
2016-06-02 |
Dev Center Biotechnology |
Anticuerpos anti-factor de crecimiento endotelial vascular (vegf) y uso de los mismos.
|
|
JOP20200094A1
(ar)
|
2014-01-24 |
2017-06-16 |
Dana Farber Cancer Inst Inc |
جزيئات جسم مضاد لـ pd-1 واستخداماتها
|
|
JOP20200096A1
(ar)
|
2014-01-31 |
2017-06-16 |
Children’S Medical Center Corp |
جزيئات جسم مضاد لـ tim-3 واستخداماتها
|
|
TWI558399B
(zh)
|
2014-02-26 |
2016-11-21 |
美國禮來大藥廠 |
癌症之組合療法
|
|
TW201622744A
(zh)
|
2014-03-04 |
2016-07-01 |
美國禮來大藥廠 |
癌症之組合療法
|
|
ES2770684T3
(es)
|
2014-03-14 |
2020-07-02 |
Novartis Ag |
Moléculas de anticuerpos contra LAG-3 y usos de los mismos
|
|
WO2015148531A1
(en)
|
2014-03-24 |
2015-10-01 |
Genentech, Inc. |
Cancer treatment with c-met antagonists and correlation of the latter with hgf expression
|
|
CA2943834A1
(en)
|
2014-03-31 |
2015-10-08 |
Genentech, Inc. |
Combination therapy comprising anti-angiogenesis agents and ox40 binding agonists
|
|
EA201692109A1
(ru)
|
2014-05-01 |
2017-03-31 |
Дженентек, Инк. |
Варианты антител к фактору d и их применение
|
|
US9388239B2
(en)
|
2014-05-01 |
2016-07-12 |
Consejo Nacional De Investigation Cientifica |
Anti-human VEGF antibodies with unusually strong binding affinity to human VEGF-A and cross reactivity to human VEGF-B
|
|
CN107073121A
(zh)
|
2014-06-13 |
2017-08-18 |
基因泰克公司 |
治疗及预防癌症药物抗性的方法
|
|
US9840553B2
(en)
|
2014-06-28 |
2017-12-12 |
Kodiak Sciences Inc. |
Dual PDGF/VEGF antagonists
|
|
WO2016011052A1
(en)
|
2014-07-14 |
2016-01-21 |
Genentech, Inc. |
Diagnostic methods and compositions for treatment of glioblastoma
|
|
RU2718914C2
(ru)
|
2014-09-13 |
2020-04-15 |
Новартис Аг |
Сочетанные способы лечения с использованием ингибиторов alk
|
|
US20160137727A1
(en)
|
2014-09-15 |
2016-05-19 |
Genentech, Inc. |
Antibody formulations
|
|
EP3200775B1
(en)
|
2014-10-03 |
2019-11-20 |
Novartis AG |
Combination therapies
|
|
MA41044A
(fr)
|
2014-10-08 |
2017-08-15 |
Novartis Ag |
Compositions et procédés d'utilisation pour une réponse immunitaire accrue et traitement contre le cancer
|
|
US9988452B2
(en)
|
2014-10-14 |
2018-06-05 |
Novartis Ag |
Antibody molecules to PD-L1 and uses thereof
|
|
KR20210013299A
(ko)
|
2014-10-17 |
2021-02-03 |
코디악 사이언시스 인코포레이티드 |
부티릴콜린에스테라제 양성이온성 중합체 컨쥬게이트
|
|
MX382902B
(es)
|
2014-10-31 |
2025-03-13 |
Oncomed Pharm Inc |
Inhibidor de la vía noth en combinación con un agente inmunoterapéutico para usarse en el tratamiento de cáncer.
|
|
SG11201703767XA
(en)
|
2014-11-10 |
2017-06-29 |
Genentech Inc |
Anti-interleukin-33 antibodies and uses thereof
|
|
JP6859259B2
(ja)
|
2014-11-19 |
2021-04-14 |
ジェネンテック， インコーポレイテッド |
ＢＡＣＥｌに対する抗体及び神経疾患免疫療法のためのその使用
|
|
EP3221361B1
(en)
|
2014-11-19 |
2021-04-21 |
Genentech, Inc. |
Anti-transferrin receptor / anti-bace1 multispecific antibodies and methods of use
|
|
PL3227332T3
(pl)
|
2014-12-03 |
2020-06-15 |
F. Hoffmann-La Roche Ag |
Wielospecyficzne przeciwciała
|
|
WO2016094881A2
(en)
|
2014-12-11 |
2016-06-16 |
Abbvie Inc. |
Lrp-8 binding proteins
|
|
US20170340733A1
(en)
|
2014-12-19 |
2017-11-30 |
Novartis Ag |
Combination therapies
|
|
CN107109491A
(zh)
|
2014-12-23 |
2017-08-29 |
豪夫迈·罗氏有限公司 |
用于治疗和诊断化学疗法抗性癌症的组合物和方法
|
|
CN108025066B
(zh)
|
2015-05-12 |
2022-04-12 |
Synt免疫公司 |
人源化亲和力成熟的抗FcRn抗体
|
|
MX2017015618A
(es)
|
2015-06-03 |
2018-08-15 |
Boston Biomedical Inc |
Composiciones que comprenden un inhibidor de la autorrenovación y diferenciación de células madre cancerosas y un agente inmunoterapéutico para su uso en el tratamiento del cáncer.
|
|
TW201711702A
(zh)
|
2015-06-04 |
2017-04-01 |
應克隆公司 |
使用針對纖維母細胞生長因子受體３（ｆｇｆｒ３）之化合物的療法
|
|
AU2016274584A1
(en)
|
2015-06-08 |
2018-01-04 |
Genentech, Inc. |
Methods of treating cancer using anti-OX40 antibodies and PD-1 axis binding antagonists
|
|
TW201710286A
(zh)
|
2015-06-15 |
2017-03-16 |
艾伯維有限公司 |
抗ｖｅｇｆ、ｐｄｇｆ及／或其受體之結合蛋白
|
|
TW201716439A
(zh)
|
2015-07-20 |
2017-05-16 |
美國禮來大藥廠 |
Ｈｅｒ３抗體
|
|
US20180222982A1
(en)
|
2015-07-29 |
2018-08-09 |
Novartis Ag |
Combination therapies comprising antibody molecules to pd-1
|
|
HRP20211058T8
(hr)
|
2015-07-29 |
2021-11-26 |
Novartis Ag |
Kombinirane terapije koje sadrže molekule antitijela protiv lag-3
|
|
EP3878465A1
(en)
|
2015-07-29 |
2021-09-15 |
Novartis AG |
Combination therapies comprising antibody molecules to tim-3
|
|
IL257565B2
(en)
*
|
2015-09-23 |
2024-08-01 |
Genentech Inc |
Optimized variants of anti-vegf antibodies
|
|
CN109071644B
(zh)
|
2015-09-23 |
2023-09-19 |
昂考梅德药品有限公司 |
治疗癌症的方法和组合物
|
|
JP2018531980A
(ja)
|
2015-10-30 |
2018-11-01 |
ジェネンテック， インコーポレイテッド |
抗ｄ因子抗体製剤
|
|
US10407510B2
(en)
|
2015-10-30 |
2019-09-10 |
Genentech, Inc. |
Anti-factor D antibodies and conjugates
|
|
BR112018007703A2
(pt)
|
2015-10-30 |
2018-11-06 |
Genentech Inc |
anticorpos, ácido nucleico isolado, métodos de produção de um anticorpo e de tratamento de um distúrbio, composição farmacêutica, terapia de combinação e uso do anticorpo
|
|
WO2017075252A1
(en)
|
2015-10-30 |
2017-05-04 |
Genentech, Inc. |
Anti-factor d antibody variant conjugates and uses thereof
|
|
DK3370768T3
(da)
|
2015-11-03 |
2022-03-21 |
Janssen Biotech Inc |
Antistoffer som specifikt binder pd-1 og anvendelser deraf
|
|
BR112018012138A2
(pt)
|
2015-12-17 |
2018-12-04 |
Novartis Ag |
moléculas de anticorpo para pd-1 e usos das mesmas
|
|
NZ744185A
(en)
|
2015-12-30 |
2025-09-26 |
Kodiak Sciences Inc |
Antibodies and conjugates thereof
|
|
CN108699141B
(zh)
|
2016-01-06 |
2022-06-17 |
定制药品研究株式会社 |
高亲和性抗vegf抗体
|
|
WO2017119434A1
(ja)
|
2016-01-06 |
2017-07-13 |
株式会社オーダーメードメディカルリサーチ |
Ｖｅｇｆとｎｒｐ１との結合を阻害する抗体
|
|
EP3432927A4
(en)
|
2016-03-24 |
2019-11-20 |
Gensun Biopharma Inc. |
TRIPLE-SPECIFIC INHIBITORS FOR CANCER TREATMENT
|
|
AU2017248766A1
(en)
|
2016-04-15 |
2018-11-01 |
Genentech, Inc. |
Methods for monitoring and treating cancer
|
|
WO2017181111A2
(en)
|
2016-04-15 |
2017-10-19 |
Genentech, Inc. |
Methods for monitoring and treating cancer
|
|
WO2017180461A1
(en)
|
2016-04-15 |
2017-10-19 |
Eli Lilly And Company |
Combination therapy of ramucirumab and abemaciclib for use in treatment of mantle cell lymphoma
|
|
CN109069632A
(zh)
|
2016-04-15 |
2018-12-21 |
伊莱利利公司 |
用于治疗结直肠癌的雷莫芦单抗和merestinib的组合
|
|
KR20190015704A
(ko)
|
2016-04-25 |
2019-02-14 |
신티뮨, 인크. |
인간화된 친화성 성숙 항-fcrn 항체
|
|
EP3463456A1
(en)
|
2016-06-03 |
2019-04-10 |
ImClone LLC |
Combination of ramucirumab and pembrolizumab for the treatment of certain cancers
|
|
EP3481946A1
(en)
|
2016-07-07 |
2019-05-15 |
The European Molecular Biology Laboratory |
Viral polypeptide fragments that bind cellular pol ii c-terminal domain (ctd) and their uses
|
|
TW202434291A
(zh)
|
2016-07-08 |
2024-09-01 |
美商建南德克公司 |
人類副睪蛋白4 (he4)用於評定癌症治療反應性之用途
|
|
WO2018009939A1
(en)
|
2016-07-08 |
2018-01-11 |
Genentech, Inc. |
Methods for diagnosing and treating cancer by means of the expression status and mutational status of nrf2 and downstream target genes of said gene.
|
|
WO2018011344A1
(en)
|
2016-07-15 |
2018-01-18 |
F. Hoffmann-La Roche Ag |
Method and means for detecting the level of total vegf-a
|
|
JPWO2018030193A1
(ja)
*
|
2016-08-08 |
2019-06-06 |
コニカミノルタ株式会社 |
実験動物の腫瘍組織の評価に関する方法
|
|
JP6644956B2
(ja)
*
|
2016-09-07 |
2020-02-12 |
サクシン ライフサイエンシス ピーヴィーティー エルティディーＳａｋｓｉｎ Ｌｉｆｅｓｃｉｅｎｃｅｓ Ｐｖｔ Ｌｔｄ |
Ｖｅｇｆに対する合成の抗体およびそれらの使用
|
|
PE20190576A1
(es)
|
2016-09-29 |
2019-04-22 |
Beijing Hanmi Pharmaceutical Co Ltd |
Construcciones de inmunoglobulina heterodimericas y metodos de preparacion de las mismas
|
|
JP2019534888A
(ja)
|
2016-10-28 |
2019-12-05 |
イムクローン・リミテッド・ライアビリティ・カンパニーＩｍｃｌｏｎｅ ＬＬＣ |
癌の治療のための抗ｖｅｇｆｒ−２抗体と抗ｐｄ−ｌ１抗体との組み合わせ
|
|
CN109952315A
(zh)
|
2016-11-16 |
2019-06-28 |
伊莱利利公司 |
用于转移性结直肠癌的治疗
|
|
EP3541383B1
(en)
|
2016-11-16 |
2021-01-06 |
Eli Lilly and Company |
Combination therapy for cancer with exon 14 skipping mutation(s) or exon 14 skipping phenotype
|
|
MX2019005858A
(es)
|
2016-11-18 |
2019-08-12 |
Beijing Hanmi Pharmaceutical Co Ltd |
Anticuerpo biespecifico heterodimerico estructural de anticuerpo natural anti-pd-1/anti-her2 y metodo para preparar el mismo.
|
|
JP7106563B2
(ja)
|
2016-11-29 |
2022-07-26 |
スミトモ ファーマ オンコロジー， インコーポレイテッド |
ナフトフラン誘導体、その調製、および使用方法
|
|
CN109071656B
(zh)
|
2017-01-05 |
2021-05-18 |
璟尚生物制药公司 |
检查点调节物拮抗剂
|
|
PL3589754T3
(pl)
|
2017-03-01 |
2023-10-09 |
F. Hoffmann-La Roche Ag |
Sposoby diagnostyczne i terapeutyczne w chorobach nowotworowych
|
|
CN110891611B
(zh)
|
2017-03-22 |
2024-03-29 |
阿森迪斯制药公司 |
水凝胶交联透明质酸前药组合物和方法
|
|
CR20190481A
(es)
|
2017-03-22 |
2020-01-06 |
Genentech Inc |
Composiciones de anticuerpo optimizados para el tratamiento de trastornos oculares
|
|
WO2018213424A1
(en)
|
2017-05-17 |
2018-11-22 |
Boston Biomedical, Inc. |
Methods for treating cancer
|
|
EP3642240A1
(en)
|
2017-06-22 |
2020-04-29 |
Novartis AG |
Antibody molecules to cd73 and uses thereof
|
|
CA3066774A1
(en)
|
2017-06-22 |
2018-12-27 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
|
JP6980904B2
(ja)
|
2017-08-29 |
2021-12-15 |
バイオ−ラッド ラボラトリーズ インコーポレイテッド |
細胞を単離し分析するためのシステムおよび方法
|
|
WO2019057946A1
(en)
|
2017-09-25 |
2019-03-28 |
F. Hoffmann-La Roche Ag |
MULTI-CYCLIC AROMATIC COMPOUNDS AS D-FACTOR INHIBITORS
|
|
CN107703290A
(zh)
*
|
2017-09-30 |
2018-02-16 |
安徽伊普诺康生物技术股份有限公司 |
一种血管内皮因子检测试剂盒的制备方法
|
|
CN107727847A
(zh)
*
|
2017-09-30 |
2018-02-23 |
安徽伊普诺康生物技术股份有限公司 |
一种血管内皮因子检测试剂盒及其使用方法
|
|
EP3715844A4
(en)
|
2017-11-20 |
2021-04-14 |
Konica Minolta, Inc. |
DRUG EVALUATION PROCEDURES
|
|
US12398209B2
(en)
|
2018-01-22 |
2025-08-26 |
Janssen Biotech, Inc. |
Methods of treating cancers with antagonistic anti-PD-1 antibodies
|
|
WO2019153200A1
(zh)
|
2018-02-08 |
2019-08-15 |
北京韩美药品有限公司 |
抗pd-1/抗her2天然抗体结构样异源二聚体形式双特异抗体及其制备
|
|
AU2019218433A1
(en)
|
2018-02-11 |
2020-09-03 |
Beijing Hanmi Pharmaceutical Co., Ltd. |
Anti-PD-1/anti-VEGF natural antibody structure-like heterodimeric form bispecific antibody and preparation thereof
|
|
MX2020009152A
(es)
|
2018-03-02 |
2020-11-09 |
Kodiak Sciences Inc |
Anticuerpos de il-6 y constructos de fusion y conjugados de los mismos.
|
|
EP3770172A4
(en)
*
|
2018-03-19 |
2022-08-31 |
Pharmabcine Inc. |
ANTI-VEGFR-2 ANTIBODIES
|
|
WO2019195770A1
(en)
|
2018-04-06 |
2019-10-10 |
Atyr Pharma, Inc. |
Compositions and methods comprising anti-nrp2 antibodies
|
|
CN113975264A
(zh)
|
2018-04-16 |
2022-01-28 |
上海岸阔医药科技有限公司 |
预防或治疗肿瘤疗法副作用的方法
|
|
WO2019225777A1
(ko)
|
2018-05-23 |
2019-11-28 |
에이비엘바이오 주식회사 |
항-ror1 항체 및 그 용도
|
|
JOP20200303A1
(ar)
|
2018-05-24 |
2020-11-23 |
Janssen Biotech Inc |
عوامل ربط psma واستخداماتها
|
|
WO2019225787A1
(ko)
|
2018-05-24 |
2019-11-28 |
에이비엘바이오 주식회사 |
항-b7-h3 항체 및 그 용도
|
|
UY38247A
(es)
|
2018-05-30 |
2019-12-31 |
Novartis Ag |
Anticuerpos frente a entpd2, terapias de combinación y métodos de uso de los anticuerpos y las terapias de combinación
|
|
US20210214459A1
(en)
|
2018-05-31 |
2021-07-15 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
|
CA3105101A1
(en)
|
2018-06-29 |
2020-01-02 |
Gensun Biopharma, Inc. |
Antitumor immune checkpoint regulator antagonists
|
|
TW202021618A
(zh)
|
2018-08-17 |
2020-06-16 |
美商２３與我有限公司 |
抗ｉｌ１ｒａｐ抗體及其使用方法
|
|
EP3867646A1
(en)
|
2018-10-18 |
2021-08-25 |
F. Hoffmann-La Roche AG |
Diagnostic and therapeutic methods for sarcomatoid kidney cancer
|
|
WO2020089051A1
(en)
|
2018-10-29 |
2020-05-07 |
F. Hoffmann-La Roche Ag |
Antibody formulation
|
|
AR117327A1
(es)
|
2018-12-20 |
2021-07-28 |
23Andme Inc |
Anticuerpos anti-cd96 y métodos de uso de estos
|
|
SG11202106100VA
(en)
|
2018-12-21 |
2021-07-29 |
23Andme Inc |
Anti-il-36 antibodies and methods of use thereof
|
|
US10633693B1
(en)
|
2019-04-16 |
2020-04-28 |
Celsee Diagnostics, Inc. |
System and method for leakage control in a particle capture system
|
|
US11591395B2
(en)
|
2019-04-19 |
2023-02-28 |
Janssen Biotech, Inc. |
Methods of treating prostate cancer with an anti-PSMA/CD3 antibody
|
|
MX2021013222A
(es)
|
2019-05-03 |
2022-01-06 |
Genentech Inc |
Metodos para tratar el cancer con un anticuerpo anti-pd-l1.
|
|
US11273439B2
(en)
|
2019-05-07 |
2022-03-15 |
Bio-Rad Laboratories, Inc. |
System and method for target material retrieval from microwells
|
|
JP7413408B2
(ja)
|
2019-05-07 |
2024-01-15 |
バイオ－ラッド ラボラトリーズ インコーポレイテッド |
自動化された単一細胞処理のためのシステムおよび方法
|
|
US11332546B2
(en)
|
2019-05-21 |
2022-05-17 |
The Regents Of The University Of California |
Protease inhibitory antibodies and methods of use thereof
|
|
WO2020237092A2
(en)
*
|
2019-05-21 |
2020-11-26 |
The Regents Of The University Of California |
Mmp-9 antibodies and methods of use thereof
|
|
WO2020260595A1
(en)
|
2019-06-26 |
2020-12-30 |
Oncurious Nv |
Combination treatment of medulloblastoma using a placental growth factor inhibitor and a chemotherapeutic agent
|
|
JP2022539739A
(ja)
*
|
2019-06-26 |
2022-09-13 |
バイオ－ラッド ラボラトリーズ インコーポレイテッド |
マイクロウェルからの標的物質の回収システムおよび方法
|
|
WO2020263312A1
(en)
|
2019-06-28 |
2020-12-30 |
Gensun Biopharma, Inc. |
ANTITUMOR ANTAGONIST CONSISTING OF A MUTATED TGFβ1 - RII EXTRACELLULAR DOMAIN AND AN IMMUNOGLOBULIN SCAFFOLD
|
|
KR20220034868A
(ko)
*
|
2019-07-19 |
2022-03-18 |
사이노셀테크 엘티디. |
인간화 항-VEGF Fab 항체 단편 및 이의 용도
|
|
JP7352007B2
(ja)
*
|
2019-07-19 |
2023-09-27 |
神州細胞工程有限公司 |
ヒト化抗ｖｅｇｆモノクローナル抗体
|
|
JP7315781B2
(ja)
|
2019-07-22 |
2023-07-26 |
エフ． ホフマン－ラ ロシュ アーゲー |
子宮内膜症の非侵襲的診断のための血液バイオマーカーとしてのｓ１００ａ１２
|
|
EP4004555A1
(en)
|
2019-07-22 |
2022-06-01 |
F. Hoffmann-La Roche AG |
S100a6 as blood biomarker for the non-invasive diagnosis of endometriosis
|
|
EP4004553A1
(en)
|
2019-07-22 |
2022-06-01 |
F. Hoffmann-La Roche AG |
S100a8 as blood biomarker for the non-invasive diagnosis of endometriosis
|
|
CN114144675A
(zh)
|
2019-07-22 |
2022-03-04 |
豪夫迈·罗氏有限公司 |
S100a9作为血液生物标志物用于子宫内膜异位症的非侵入性诊断
|
|
JP7315780B2
(ja)
|
2019-07-22 |
2023-07-26 |
エフ． ホフマン－ラ ロシュ アーゲー |
子宮内膜症の非侵襲的診断のための血液バイオマーカーとしてのサブスタンスｐ
|
|
JP2022548881A
(ja)
|
2019-09-18 |
2022-11-22 |
ノバルティス アーゲー |
Ｅｎｔｐｄ２抗体、組合せ療法並びに抗体及び組合せ療法を使用する方法
|
|
WO2021067761A1
(en)
*
|
2019-10-03 |
2021-04-08 |
Atyr Pharma, Inc. |
Compositions and methods comprising anti-nrp2 antibodies
|
|
WO2021072265A1
(en)
|
2019-10-10 |
2021-04-15 |
Kodiak Sciences Inc. |
Methods of treating an eye disorder
|
|
WO2021094409A1
(en)
|
2019-11-15 |
2021-05-20 |
F. Hoffmann-La Roche Ag |
Derivatization of beta-lactam antibiotics for massspec measurements in patient samples
|
|
WO2021102173A1
(en)
*
|
2019-11-21 |
2021-05-27 |
Unity Biotechnology |
Antibodies directed to tie-2 and methods of use
|
|
EP4118114A1
(en)
|
2020-03-13 |
2023-01-18 |
Genentech, Inc. |
Anti-interleukin-33 antibodies and uses thereof
|
|
CN115916963A
(zh)
|
2020-03-27 |
2023-04-04 |
门德斯有限公司 |
白血病来源的经修饰细胞用于增强过继性细胞治疗的效力的离体用途
|
|
WO2021202959A1
(en)
|
2020-04-03 |
2021-10-07 |
Genentech, Inc. |
Therapeutic and diagnostic methods for cancer
|
|
EP4139684A1
(en)
|
2020-04-23 |
2023-03-01 |
F. Hoffmann-La Roche AG |
Corona nucleocapsid antigen for use in antibody-immunoassays
|
|
KR20230018425A
(ko)
|
2020-05-29 |
2023-02-07 |
23앤드미 인코포레이티드 |
항-cd200r1 항체 및 이의 사용 방법
|
|
EP4168443A1
(en)
|
2020-06-22 |
2023-04-26 |
Almirall S.A. |
Anti-il-36 antibodies and methods of use thereof
|
|
KR20230033647A
(ko)
|
2020-06-30 |
2023-03-08 |
멘두스 비.브이. |
난소암 백신에서 백혈병 유래 세포의 용도
|
|
WO2022003156A1
(en)
|
2020-07-02 |
2022-01-06 |
Oncurious Nv |
Ccr8 non-blocking binders
|
|
EP3943946A1
(en)
|
2020-07-20 |
2022-01-26 |
F. Hoffmann-La Roche AG |
Gdf-15 for predicting the disease severity of a patient with covid-19
|
|
TW202227496A
(zh)
|
2020-09-14 |
2022-07-16 |
瑞士商伊克諾斯科學公司 |
結合至ｉｌ１ｒａｐ之抗體及其用途
|
|
EP4228674A4
(en)
*
|
2020-10-15 |
2025-01-29 |
Bioincept LLC |
SYSTEMS, COMPOSITIONS AND METHODS FOR DETERMINING THE VIABILITY OF EMBRYOS
|
|
JP2023547505A
(ja)
|
2020-11-02 |
2023-11-10 |
エフ． ホフマン－ラ ロシュ アーゲー |
ＳＡＲＳ－ＣｏＶ－２ヌクレオカプシド抗体
|
|
TW202535399A
(zh)
|
2020-11-13 |
2025-09-16 |
美商建南德克公司 |
用於治療實性瘤之方法與包含 krasg12c 抑制劑及 vegf 抑制劑之組成物
|
|
JP2024508207A
(ja)
|
2020-12-02 |
2024-02-26 |
ブイアイビー ブイゼットダブリュ |
がんに対する組み合わせ治療におけるｌｔｂｒアゴニスト
|
|
WO2022117569A1
(en)
|
2020-12-02 |
2022-06-09 |
Oncurious Nv |
A ccr8 antagonist antibody in combination with a lymphotoxin beta receptor agonist antibody in therapy against cancer
|
|
MX2023006690A
(es)
|
2020-12-08 |
2023-06-19 |
Genentech Inc |
Procedimientos y composiciones que comprenden un inhibidor de krasg12c y un inhibidor de egfr para el tratamiento de tumores solidos.
|
|
US20240052044A1
(en)
|
2020-12-24 |
2024-02-15 |
Vib Vzw |
Non-blocking human ccr8 binders
|
|
EP4267617A1
(en)
|
2020-12-24 |
2023-11-01 |
Vib Vzw |
Human ccr8 binders
|
|
EP4267621A1
(en)
|
2020-12-24 |
2023-11-01 |
Vib Vzw |
Murine cross-reactive human ccr8 binders
|
|
EP4281102A1
(en)
|
2021-01-22 |
2023-11-29 |
Mendus B.V. |
Methods of tumor vaccination
|
|
PE20240761A1
(es)
|
2021-01-28 |
2024-04-17 |
Janssen Biotech Inc |
Proteinas de union a psma y usos de estas
|
|
AR124914A1
(es)
*
|
2021-02-18 |
2023-05-17 |
Mitsubishi Tanabe Pharma Corp |
Nuevo anticuerpo anti-pad4
|
|
WO2022190058A1
(en)
|
2021-03-12 |
2022-09-15 |
Dcprime B.V. |
Methods of vaccination and use of cd47 blockade
|
|
CN112961243B
(zh)
*
|
2021-03-24 |
2022-04-29 |
山东兴瑞生物科技有限公司 |
一种vegf抗体、重组aav病毒及其应用
|
|
WO2022207628A1
(en)
|
2021-03-30 |
2022-10-06 |
F. Hoffmann-La Roche Ag |
Scf as blood biomarker for the non-invasive diagnosis of endometriosis
|
|
CN117099001A
(zh)
|
2021-04-01 |
2023-11-21 |
豪夫迈·罗氏有限公司 |
Psp94作为血液生物标志物用于子宫内膜异位症的非侵入性诊断
|
|
BR112023022439A2
(pt)
|
2021-04-26 |
2023-12-26 |
Celanese Eva Performance Polymers Llc |
Dispositivo implantável para liberação sustentada de um composto de fármaco macromolecular
|
|
JP2024516230A
(ja)
|
2021-04-30 |
2024-04-12 |
ジェネンテック， インコーポレイテッド |
がんのための治療及び診断方法並びに組成物
|
|
EP4341700A1
(en)
|
2021-05-17 |
2024-03-27 |
F. Hoffmann-La Roche AG |
Sfrp4 as blood biomarker for the non-invasive diagnosis of adenomyosis
|
|
US20240279324A1
(en)
|
2021-06-03 |
2024-08-22 |
Gensun Biopharma Inc. |
Multispecific antagonists
|
|
KR20240028452A
(ko)
|
2021-07-02 |
2024-03-05 |
제넨테크, 인크. |
암을 치료하기 위한 방법 및 조성물
|
|
US12281161B2
(en)
|
2021-07-28 |
2025-04-22 |
Trustees Of Boston University |
Polypeptides and uses thereof
|
|
KR20240038008A
(ko)
|
2021-07-28 |
2024-03-22 |
에프. 호프만-라 로슈 아게 |
암 치료 방법 및 조성물
|
|
CN118434762A
(zh)
|
2021-10-26 |
2024-08-02 |
豪夫迈·罗氏有限公司 |
对SARS-CoV-2 RBD具有特异性的单克隆抗体
|
|
WO2023080900A1
(en)
|
2021-11-05 |
2023-05-11 |
Genentech, Inc. |
Methods and compositions for classifying and treating kidney cancer
|
|
EP4444910A4
(en)
|
2021-12-10 |
2025-11-05 |
Bio Rad Laboratories Inc |
Compositions, processes and systems for the treatment of samples with functionalized particles of adjustable morphology
|
|
WO2023144973A1
(ja)
|
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|
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|
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|
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|
|
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|
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|
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|
|
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|
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|
|
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|
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|
|
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|
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|
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|
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|
|
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|
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|
|
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(en)
|
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|
|
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(en)
|
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|
|
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(en)
|
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|
|
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(en)
|
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|
|
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(en)
|
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|
|
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(en)
|
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|
|
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(en)
|
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|
|
WO2025128837A1
(en)
*
|
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|