JP2015509948A5 - - Google Patents
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- JP2015509948A5 JP2015509948A5 JP2014558901A JP2014558901A JP2015509948A5 JP 2015509948 A5 JP2015509948 A5 JP 2015509948A5 JP 2014558901 A JP2014558901 A JP 2014558901A JP 2014558901 A JP2014558901 A JP 2014558901A JP 2015509948 A5 JP2015509948 A5 JP 2015509948A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- chain variable
- variable region
- antibody
- heavy chain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261603203P | 2012-02-24 | 2012-02-24 | |
| US61/603,203 | 2012-02-24 | ||
| PCT/US2013/027476 WO2013126810A1 (en) | 2012-02-24 | 2013-02-22 | Anti sez6 antibodies and methods of use |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018052506A Division JP2018127469A (ja) | 2012-02-24 | 2018-03-20 | 抗ｓｅｚ６抗体及び使用方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015509948A JP2015509948A (ja) | 2015-04-02 |
| JP2015509948A5 true JP2015509948A5 (enExample) | 2016-04-14 |
| JP6401060B2 JP6401060B2 (ja) | 2018-10-03 |
Family
ID=47790548
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014558901A Expired - Fee Related JP6401060B2 (ja) | 2012-02-24 | 2013-02-22 | 抗ｓｅｚ６抗体及び使用方法 |
| JP2018052506A Pending JP2018127469A (ja) | 2012-02-24 | 2018-03-20 | 抗ｓｅｚ６抗体及び使用方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018052506A Pending JP2018127469A (ja) | 2012-02-24 | 2018-03-20 | 抗ｓｅｚ６抗体及び使用方法 |
Country Status (20)
| Country | Link |
|---|---|
| US (3) | US9676850B2 (enExample) |
| EP (2) | EP2817339B1 (enExample) |
| JP (2) | JP6401060B2 (enExample) |
| KR (1) | KR102099073B1 (enExample) |
| CN (2) | CN104334580B (enExample) |
| AU (3) | AU2013203506B2 (enExample) |
| CA (1) | CA2865415C (enExample) |
| CL (2) | CL2014002237A1 (enExample) |
| CO (1) | CO7151485A2 (enExample) |
| ES (1) | ES2741936T3 (enExample) |
| IL (1) | IL234208B (enExample) |
| MX (2) | MX373141B (enExample) |
| MY (1) | MY178120A (enExample) |
| NZ (1) | NZ631197A (enExample) |
| PE (1) | PE20150091A1 (enExample) |
| PH (2) | PH12020500604A1 (enExample) |
| RU (1) | RU2691698C2 (enExample) |
| SG (2) | SG11201405130UA (enExample) |
| WO (1) | WO2013126810A1 (enExample) |
| ZA (1) | ZA201406967B (enExample) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
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| KR102099073B1 (ko) * | 2012-02-24 | 2020-04-10 | 애브비 스템센트알엑스 엘엘씨 | 항 ｓｅｚ6 항체들 및 사용 방법 |
| US11531028B2 (en) * | 2013-05-10 | 2022-12-20 | Nordic Bioscience A/S | Collagen type X alpha-1 assay |
| JP2016538318A (ja) * | 2013-08-28 | 2016-12-08 | ステムセントリックス， インコーポレイテッド | 新規ｓｅｚ６モジュレーターおよび使用方法 |
| WO2015031698A1 (en) * | 2013-08-28 | 2015-03-05 | Stem Centrx, Inc. | Site-specific antibody conjugation methods and compositions |
| WO2015065954A1 (en) * | 2013-11-04 | 2015-05-07 | Pfizer, Inc. | Anti-efna4 antibody-drug conjugates |
| SG11201604503XA (en) * | 2013-12-03 | 2016-07-28 | Agency Science Tech & Res | Cytotoxic antibody |
| JP6517156B2 (ja) * | 2014-01-29 | 2019-05-22 | Ｋｍバイオロジクス株式会社 | 抗トランスサイレチンヒト抗体 |
| JP6818268B2 (ja) * | 2014-01-29 | 2021-01-20 | Ｋｍバイオロジクス株式会社 | 抗トランスサイレチンヒト化抗体 |
| KR20170008202A (ko) | 2014-02-21 | 2017-01-23 | 애브비 스템센트알엑스 엘엘씨 | 흑색종에 사용하기 위한 항-ｄｌｌ3 항체 및 약물 접합체 |
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| EP3204414B1 (en) * | 2014-10-07 | 2024-12-04 | Ann and Robert H. Lurie Children's Hospital of Chicago | Novel anti-nodal antibodies and methods of using same |
| JP2018529656A (ja) * | 2015-08-20 | 2018-10-11 | アッヴィ・ステムセントルクス・エル・エル・シー | 抗ｄｌｌ３抗体薬物コンジュゲートおよび使用方法 |
| CN114910886A (zh) | 2015-10-06 | 2022-08-16 | 日本先锋公司 | 光控制装置、光控制方法和程序 |
| WO2017087547A1 (en) * | 2015-11-17 | 2017-05-26 | Oncomed Pharmaceuticals, Inc. | Pd-l1-binding agents and uses thereof |
| US10537633B2 (en) | 2016-03-04 | 2020-01-21 | Jn Biosciences Llc | Antibodies to TIGIT |
| WO2018071718A1 (en) * | 2016-10-14 | 2018-04-19 | Nima Labs, Inc. | Anti-gliadin antibodies |
| EP3529280A4 (en) * | 2016-10-19 | 2020-04-22 | Novelogics Biotechnology, Inc. | ANTIBODIES AGAINST MICA AND MICB PROTEINS |
| WO2018107116A1 (en) * | 2016-12-09 | 2018-06-14 | Abbvie Stemcentrx Llc | Methods of reducing toxicity of antibody drug conjugates, and compositions produced thereby |
| EP3559043A4 (en) | 2016-12-23 | 2020-08-05 | Bluefin Biomedicine, Inc. | ANTI-SEZ6L2 ANTIBODIES AND ANTIBODY-DRUG CONJUGATES |
| EP3424528A1 (de) | 2017-07-07 | 2019-01-09 | AVA Lifescience GmbH | Biologische bindemoleküle |
| WO2019196117A1 (en) | 2018-04-13 | 2019-10-17 | Dingfu Biotarget Co., Ltd. | Anti-cd27 antibodies and use thereof |
| RU2770474C1 (ru) * | 2018-05-30 | 2022-04-18 | ЭББВИ СТЕМСЕНТРКС ЭлЭлСи | Конъюгаты антитело к sez6-лекарственное средство и способы применения |
| WO2020013644A1 (ko) * | 2018-07-11 | 2020-01-16 | 고려대학교 산학협력단 | Smo 단백질의 특이적 에피토프, 이를 인지하는 항체 및 이를 포함하는 조성물 |
| KR20250172902A (ko) | 2018-07-31 | 2025-12-09 | 다이이찌 산쿄 가부시키가이샤 | 항체-약물 콘주게이트 투여에 의한 전이성 뇌종양의 치료 |
| BR112021002989A2 (pt) * | 2018-08-24 | 2021-05-11 | Jiangsu Hengrui Medicine Co., Ltd. | anticorpo para ligação de il-4r de humano, fragmento para ligação de antígeno e uso médico do mesmo |
| CR20220611A (es) | 2020-06-02 | 2023-06-07 | Arcus Biosciences Inc | Anticuerpos anti-tigit |
| CN114106176B (zh) * | 2020-09-01 | 2024-04-09 | 深圳市菲鹏生物治疗股份有限公司 | Cd22抗体及其应用 |
| US20230287090A1 (en) * | 2020-09-02 | 2023-09-14 | The Feinstein Institutes For Medical Research | USE OF SARS-CoV-2 RECEPTOR BINDING MOTIF (RBM)-REACTIVE MONOCLONAL ANTIBODIES TO TREAT COVID-19 |
| EP4251209A1 (en) | 2020-11-24 | 2023-10-04 | Novartis AG | Bcl-xl inhibitor antibody-drug conjugates and methods of use thereof |
| CN114790241B (zh) * | 2021-01-26 | 2024-12-13 | 北京免疫方舟医药科技有限公司 | 抗tigit抗体及其应用 |
| CN113307875B (zh) * | 2021-06-10 | 2022-09-02 | 福州迈新生物技术开发有限公司 | 抗TCRβF1蛋白单克隆抗体及其细胞株、制备方法和应用 |
| WO2023019174A2 (en) * | 2021-08-11 | 2023-02-16 | Apollos Diagnostics, Llc | Antibodies to sars-cov-2 |
| US20250387504A1 (en) | 2022-05-20 | 2025-12-25 | Novartis Ag | Antibody-drug conjugates of antineoplastic compounds and methods of use thereof |
| IL316653A (en) | 2022-05-20 | 2024-12-01 | Novartis Ag | Antibody drug conjugates |
| CN115975036B (zh) * | 2022-08-18 | 2023-06-09 | 北京诺赛国际医学研究院 | 包含干细胞的药物组合物及其治疗癌症的用途 |
| AU2024270504A1 (en) | 2023-05-08 | 2025-11-27 | Changzhou Hansoh Pharmaceutical Co., Ltd. | Antibody or antigen-binding fragment thereof, antibody-drug conjugate, and use thereof |
| CN117736331B (zh) * | 2024-02-04 | 2024-05-07 | 南昌大学第一附属医院 | 一种特异性结合psma胞外段的单克隆抗体及其应用 |
| WO2025167503A1 (en) * | 2024-02-05 | 2025-08-14 | Biocytogen Pharmaceuticals (Beijing) Co., Ltd. | Anti-sez6/b7h3 antibodies and uses thereof |
| CN120904329A (zh) * | 2024-10-18 | 2025-11-07 | 北京大学第一医院(北京大学第一临床医学院) | 一种抗sez6纳米抗体或抗原结合片段与应用 |
| CN120365421B (zh) * | 2025-04-24 | 2025-11-04 | 成都古格尔生物技术有限公司 | 一种特异性抗sez6靶点的全人源抗体及其制备方法和应用 |
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-
2013
- 2013-02-22 KR KR1020147026846A patent/KR102099073B1/ko not_active Expired - Fee Related
- 2013-02-22 CN CN201380010534.6A patent/CN104334580B/zh not_active Expired - Fee Related
- 2013-02-22 AU AU2013203506A patent/AU2013203506B2/en not_active Ceased
- 2013-02-22 JP JP2014558901A patent/JP6401060B2/ja not_active Expired - Fee Related
- 2013-02-22 RU RU2014138420A patent/RU2691698C2/ru active
- 2013-02-22 SG SG11201405130UA patent/SG11201405130UA/en unknown
- 2013-02-22 MX MX2014010094A patent/MX373141B/es active IP Right Grant
- 2013-02-22 WO PCT/US2013/027476 patent/WO2013126810A1/en not_active Ceased
- 2013-02-22 ES ES13707529T patent/ES2741936T3/es active Active
- 2013-02-22 US US14/380,665 patent/US9676850B2/en active Active
- 2013-02-22 PE PE2014001301A patent/PE20150091A1/es active IP Right Grant
- 2013-02-22 SG SG10201801444WA patent/SG10201801444WA/en unknown
- 2013-02-22 PH PH1/2020/500604A patent/PH12020500604A1/en unknown
- 2013-02-22 EP EP13707529.7A patent/EP2817339B1/en active Active
- 2013-02-22 CA CA2865415A patent/CA2865415C/en active Active
- 2013-02-22 NZ NZ631197A patent/NZ631197A/en not_active IP Right Cessation
- 2013-02-22 CN CN201810153825.5A patent/CN108383909B/zh not_active Expired - Fee Related
- 2013-02-22 EP EP19154773.6A patent/EP3539985A1/en not_active Withdrawn
- 2013-02-22 MY MYPI2014002467A patent/MY178120A/en unknown
-
2014
- 2014-08-19 IL IL234208A patent/IL234208B/en active IP Right Grant
- 2014-08-21 MX MX2020003713A patent/MX2020003713A/es unknown
- 2014-08-22 CL CL2014002237A patent/CL2014002237A1/es unknown
- 2014-08-26 PH PH12014501914A patent/PH12014501914B1/en unknown
- 2014-09-23 ZA ZA2014/06967A patent/ZA201406967B/en unknown
- 2014-09-23 CO CO14210871A patent/CO7151485A2/es unknown
-
2016
- 2016-09-07 AU AU2016225828A patent/AU2016225828B2/en not_active Ceased
-
2017
- 2017-06-05 US US15/614,548 patent/US10533051B2/en not_active Expired - Fee Related
- 2017-11-08 CL CL2017002823A patent/CL2017002823A1/es unknown
-
2018
- 2018-03-20 JP JP2018052506A patent/JP2018127469A/ja active Pending
- 2018-08-31 AU AU2018223053A patent/AU2018223053B2/en not_active Expired - Fee Related
-
2019
- 2019-12-12 US US16/712,324 patent/US20200181256A1/en not_active Abandoned
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