JP2014502955A5 - - Google Patents
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- Publication number
- JP2014502955A5 JP2014502955A5 JP2013534894A JP2013534894A JP2014502955A5 JP 2014502955 A5 JP2014502955 A5 JP 2014502955A5 JP 2013534894 A JP2013534894 A JP 2013534894A JP 2013534894 A JP2013534894 A JP 2013534894A JP 2014502955 A5 JP2014502955 A5 JP 2014502955A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- seq
- amino acid
- acid sequence
- variable region
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40509010P | 2010-10-20 | 2010-10-20 | |
| US61/405,090 | 2010-10-20 | ||
| PCT/US2011/001787 WO2012054084A2 (en) | 2010-10-20 | 2011-10-19 | Antibodies |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014502955A JP2014502955A (ja) | 2014-02-06 |
| JP2014502955A5 true JP2014502955A5 (enExample) | 2014-12-11 |
Family
ID=45975790
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013534894A Pending JP2014502955A (ja) | 2010-10-20 | 2011-10-19 | 抗体 |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US20130259878A1 (enExample) |
| EP (1) | EP2629796A4 (enExample) |
| JP (1) | JP2014502955A (enExample) |
| KR (1) | KR20130138802A (enExample) |
| CN (1) | CN103534268B (enExample) |
| AU (1) | AU2011318574B2 (enExample) |
| BR (1) | BR112013009551A2 (enExample) |
| CA (1) | CA2815041A1 (enExample) |
| EA (1) | EA201300470A1 (enExample) |
| IL (1) | IL225571A0 (enExample) |
| MX (1) | MX2013004476A (enExample) |
| NZ (1) | NZ610091A (enExample) |
| SG (1) | SG189835A1 (enExample) |
| WO (1) | WO2012054084A2 (enExample) |
| ZA (1) | ZA201302459B (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ616382A (en) | 2009-04-20 | 2015-04-24 | Oxford Biotherapeutics Ltd | Antibodies specific to cadherin-17 |
| RU2648141C2 (ru) * | 2012-09-19 | 2018-03-22 | Эббви Биотерапьютикс Инк. | Способы идентификации антител с пониженной иммуногенностью |
| WO2017120557A1 (en) * | 2016-01-09 | 2017-07-13 | Arbele Limited | Cadherin-17 specific antibodies and cytotoxic cells for cancer treatment |
| SG10201800265UA (en) * | 2016-06-17 | 2018-02-27 | Chugai Pharmaceutical Co Ltd | Anti-c5 antibodies and methods of use |
| EP3360898A1 (en) * | 2017-02-14 | 2018-08-15 | Boehringer Ingelheim International GmbH | Bispecific anti-tnf-related apoptosis-inducing ligand receptor 2 and anti-cadherin 17 binding molecules for the treatment of cancer |
| MA50102A (fr) | 2017-11-14 | 2020-07-15 | Univ Virginia Patent Foundation | Compositions et méthodes de fabrication et d'utilisation d'anticorps bispécifiques |
| US12410234B2 (en) | 2018-04-26 | 2025-09-09 | The Trustees Of The University Of Pennsylvania | Compositions and methods for retrieving tumor-related antibodies and antigens |
| RU2703949C1 (ru) * | 2018-04-27 | 2019-10-22 | Открытое акционерное общество "Всероссийский научный Центр молекулярной диагностики и лечения" (ОАО ВНЦМДЛ) | Вариабельные домены лёгкой и тяжёлой цепи мышиного моноклонального антитела против кадгерина-17 человека, антигенсвязывающий фрагмент (Fab) против кадгерина-17 человека, содержащий указанные домены |
| US20210116456A1 (en) * | 2018-05-16 | 2021-04-22 | Arbele Limited | Compositions and methods for diagnosis and treatment of cancer |
| WO2019222428A1 (en) * | 2018-05-16 | 2019-11-21 | Arbele Limited | Composition of bispecific antibodies and method of use thereof |
| US20250270314A1 (en) * | 2021-08-02 | 2025-08-28 | Tavotek Biotech (Suzhou) Ltd | Anti-cdh17 monoclonal and bispecific antibodies and uses thereof |
| CN118119847A (zh) * | 2021-10-08 | 2024-05-31 | 泰贝乐医疗科技有限公司 | 用于检测cdh17的方法和组合物 |
| WO2024100294A1 (en) | 2022-11-11 | 2024-05-16 | Ospedale San Raffaele S.R.L. | Cdh17 car |
| CN120917040A (zh) * | 2023-01-31 | 2025-11-07 | 毕格哈特生物科学公司 | 抗cdh17抗体及其用途 |
| EP4669672A1 (en) * | 2023-02-23 | 2025-12-31 | Hansoh Bio LLC | ANTIBODIES, ANTIGEN-BINDING FRAGMENTS AND METHODS OF USE |
| JP2026518758A (ja) * | 2023-05-24 | 2026-06-09 | マルティテュード・セラピューティクス・インコーポレイテッド | 抗体及びその抗体薬物複合体 |
| KR20260082360A (ko) * | 2023-09-22 | 2026-06-04 | 레푸 바이오파마 컴퍼니 리미티드 | 항-cdh17 항체 및 이의 용도 |
| CN120230211A (zh) * | 2023-12-29 | 2025-07-01 | 广东菲鹏制药股份有限公司 | 抗cdh17抗体或其抗原结合片段及其应用 |
| TW202547885A (zh) * | 2024-04-30 | 2025-12-16 | 中國商蘇州宜聯生物醫藥有限公司 | 抗體、抗體藥物偶聯物及其用途 |
| TW202613168A (zh) * | 2024-05-20 | 2026-04-01 | 大陸商杭州中美華東製藥有限公司 | 抗cdh17抗體、其抗體藥物偶聯物及其用途 |
| WO2025242100A1 (zh) * | 2024-05-21 | 2025-11-27 | 康诺亚生物医药科技（成都）有限公司 | 针对cdh17的抗体及其用途 |
| TW202613172A (zh) * | 2024-05-31 | 2026-04-01 | 大陸商江蘇先聲生物製藥有限公司 | 抗cdh17抗體、綴合物及其應用 |
| WO2025252211A1 (zh) * | 2024-06-07 | 2025-12-11 | 映恩生物制药（苏州）有限公司 | 抗人cdh17抗体 |
| WO2026067602A1 (zh) * | 2024-09-26 | 2026-04-02 | 上海翰森生物医药科技有限公司 | 一种含抗体药物偶联物的药物组合物及其用途 |
| WO2026090578A1 (en) * | 2024-10-25 | 2026-04-30 | Antharis Therapeutics Inc. | Cdh17-binding antibodies and methods of use thereof |
| CN120554510B (zh) * | 2025-05-29 | 2026-05-12 | 吉林大学 | 抗钙粘蛋白-17的双表位抗体及采用其制备的抗体药物偶联物 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040049014A1 (en) * | 1988-12-28 | 2004-03-11 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| WO1996040942A1 (en) * | 1995-06-07 | 1996-12-19 | Cytel Corporation | Humanized antibodies to e-selectin |
| HUP0104865A3 (en) * | 1999-01-15 | 2004-07-28 | Genentech Inc | Polypeptide variants with altered effector function |
| WO2002057316A1 (en) * | 2000-12-28 | 2002-07-25 | Kirin Beer Kabushiki Kaisha | Novel monoclonal antibody |
| IL149820A0 (en) * | 2002-05-23 | 2002-11-10 | Curetech Ltd | Humanized immunomodulatory monoclonal antibodies for the treatment of neoplastic disease or immunodeficiency |
| DK1578446T3 (en) * | 2002-11-07 | 2015-06-29 | Immunogen Inc | ANTI-CD33 ANTIBODIES AND PROCEDURES FOR TREATING ACUTE MYELOID LEUKEMIA BY USING IT |
| US20050106667A1 (en) * | 2003-08-01 | 2005-05-19 | Genentech, Inc | Binding polypeptides with restricted diversity sequences |
| DE102004023187A1 (de) * | 2004-05-11 | 2005-12-01 | Ganymed Pharmaceuticals Ag | Identifizierung von Oberflächen-assoziierten Antigenen für die Tumordiagnose und -therapie |
| JP2006089471A (ja) * | 2004-08-26 | 2006-04-06 | National Institute Of Advanced Industrial & Technology | 癌の治療における抗モータリン２抗体と機能性核酸の使用 |
| US7615529B2 (en) * | 2005-03-25 | 2009-11-10 | Genentech, Inc. | Methods and compositions for modulating hyperstabilized c-met |
| US8535677B2 (en) * | 2006-06-06 | 2013-09-17 | Oxford Biotherapeutics, Ltd. | Antibody drug conjugate treatment of colorectal cancer |
| WO2009116670A1 (ja) * | 2008-03-17 | 2009-09-24 | 株式会社リブテック | in vivoで抗腫瘍活性を有する抗ヒトDlk-1抗体 |
| US9207242B2 (en) * | 2008-10-09 | 2015-12-08 | The University Of Hong Kong | Cadherin-17 as diagnostic marker and therapeutic target for liver cancer |
| WO2010095461A1 (ja) * | 2009-02-20 | 2010-08-26 | 国立大学法人東京大学 | 新規モノクローナル抗体、並びにその使用 |
| US8647623B2 (en) * | 2009-04-10 | 2014-02-11 | Kyowa Hakko Kirin Co., Ltd | Method for treatment of blood tumor using anti-TIM-3 antibody |
| NZ616382A (en) * | 2009-04-20 | 2015-04-24 | Oxford Biotherapeutics Ltd | Antibodies specific to cadherin-17 |
-
2011
- 2011-10-19 CN CN201180050390.8A patent/CN103534268B/zh not_active Expired - Fee Related
- 2011-10-19 US US13/880,320 patent/US20130259878A1/en not_active Abandoned
- 2011-10-19 NZ NZ610091A patent/NZ610091A/en not_active IP Right Cessation
- 2011-10-19 SG SG2013025242A patent/SG189835A1/en unknown
- 2011-10-19 WO PCT/US2011/001787 patent/WO2012054084A2/en not_active Ceased
- 2011-10-19 CA CA2815041A patent/CA2815041A1/en not_active Abandoned
- 2011-10-19 JP JP2013534894A patent/JP2014502955A/ja active Pending
- 2011-10-19 AU AU2011318574A patent/AU2011318574B2/en not_active Ceased
- 2011-10-19 BR BR112013009551A patent/BR112013009551A2/pt not_active IP Right Cessation
- 2011-10-19 KR KR1020137012771A patent/KR20130138802A/ko not_active Withdrawn
- 2011-10-19 MX MX2013004476A patent/MX2013004476A/es unknown
- 2011-10-19 EP EP11834758.2A patent/EP2629796A4/en not_active Withdrawn
- 2011-10-19 EA EA201300470A patent/EA201300470A1/ru unknown
-
2013
- 2013-04-04 IL IL225571A patent/IL225571A0/en unknown
- 2013-04-05 ZA ZA2013/02459A patent/ZA201302459B/en unknown
-
2014
- 2014-11-20 US US14/549,176 patent/US20150093392A1/en not_active Abandoned
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