JP2010520290A5 - - Google Patents

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Publication number
JP2010520290A5
JP2010520290A5 JP2009552761A JP2009552761A JP2010520290A5 JP 2010520290 A5 JP2010520290 A5 JP 2010520290A5 JP 2009552761 A JP2009552761 A JP 2009552761A JP 2009552761 A JP2009552761 A JP 2009552761A JP 2010520290 A5 JP2010520290 A5 JP 2010520290A5
Authority
JP
Japan
Prior art keywords
epha3
antibody
pharmaceutical composition
composition according
region
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2009552761A
Other languages
English (en)
Japanese (ja)
Other versions
JP2010520290A (ja
JP5311060B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2008/003149 external-priority patent/WO2008112192A2/en
Publication of JP2010520290A publication Critical patent/JP2010520290A/ja
Publication of JP2010520290A5 publication Critical patent/JP2010520290A5/ja
Application granted granted Critical
Publication of JP5311060B2 publication Critical patent/JP5311060B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2009552761A 2007-03-08 2008-03-10 固形腫瘍の治療のためのEphA3抗体 Active JP5311060B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US89384807P 2007-03-08 2007-03-08
US60/893,848 2007-03-08
PCT/US2008/003149 WO2008112192A2 (en) 2007-03-08 2008-03-10 Epha3 antibodies for the treatment of solid tumors

Publications (3)

Publication Number Publication Date
JP2010520290A JP2010520290A (ja) 2010-06-10
JP2010520290A5 true JP2010520290A5 (enExample) 2011-04-21
JP5311060B2 JP5311060B2 (ja) 2013-10-09

Family

ID=39689392

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009552761A Active JP5311060B2 (ja) 2007-03-08 2008-03-10 固形腫瘍の治療のためのEphA3抗体

Country Status (13)

Country Link
US (1) US8637016B2 (enExample)
EP (2) EP2136838B1 (enExample)
JP (1) JP5311060B2 (enExample)
CN (1) CN101641115B (enExample)
AU (1) AU2008226905C1 (enExample)
CA (1) CA2679986C (enExample)
DK (1) DK3199180T3 (enExample)
ES (1) ES2910298T3 (enExample)
IL (1) IL200764A (enExample)
NZ (1) NZ579478A (enExample)
PL (1) PL3199180T3 (enExample)
PT (1) PT3199180T (enExample)
WO (1) WO2008112192A2 (enExample)

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WO2009023184A2 (en) 2007-08-10 2009-02-19 Protelix, Inc. Universal fibronectin type iii binding-domain libraries
US8680019B2 (en) 2007-08-10 2014-03-25 Protelica, Inc. Universal fibronectin Type III binding-domain libraries
US8470966B2 (en) 2007-08-10 2013-06-25 Protelica, Inc. Universal fibronectin type III binding-domain libraries
CN102405237A (zh) * 2009-03-06 2012-04-04 卡罗拜奥斯制药公司 利用EphA3抗体治疗白血病和慢性骨髓增生性疾病
CN102666589B (zh) * 2009-10-14 2014-08-20 卡罗拜奥斯制药公司 EphA3抗体
AU2011235867B2 (en) * 2010-04-01 2015-12-03 Kalobios Pharmaceuticals, Inc. EphA3 antibodies for the treatment of multiple myeloma
JP2013537403A (ja) * 2010-06-18 2013-10-03 カロバイオス ファーマシューティカルズ インコーポレイティッド 固形腫瘍の存在のマーカーとしてのEphA3の検出
US20140302034A1 (en) * 2010-12-08 2014-10-09 Stem Centrx, Inc. Novel modulators and methods of use
WO2012158818A2 (en) 2011-05-16 2012-11-22 Fabion Pharmaceuticals, Inc. Multi-specific fab fusion proteins and methods of use
US9109032B2 (en) 2011-08-12 2015-08-18 Kalobios Pharmaceuticals, Inc. Methods of treating hematological proliferative disorders by targeting EphA3 expressed on aberrant vasculature in bone marrow
EP3068797B1 (en) 2013-11-11 2020-01-08 Wake Forest University Health Sciences Constructs for multi-valent targeting of tumors
CN109476756B (zh) 2016-03-15 2022-05-31 埃泰美德(香港)有限公司 一种多特异性Fab融合蛋白及其用途
WO2020048525A1 (en) 2018-09-07 2020-03-12 Generon (Shanghai) Corporation Ltd. Bispecific antigen binding proteins and uses thereof
WO2021068040A1 (en) * 2019-10-09 2021-04-15 The Council Of The Queensland Institute Of Medical Research Targeting epha3 and uses thereof

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