|
US6737056B1
(en)
*
|
1999-01-15 |
2004-05-18 |
Genentech, Inc. |
Polypeptide variants with altered effector function
|
|
DE10254601A1
(de)
|
2002-11-22 |
2004-06-03 |
Ganymed Pharmaceuticals Ag |
Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung
|
|
EP1910542B1
(en)
|
2005-07-22 |
2009-12-02 |
Five Prime Therapeutics, Inc. |
Compositions and methods of treating disease with fgfr fusion proteins
|
|
CA2637988A1
(en)
|
2006-02-10 |
2007-11-29 |
Genentech, Inc. |
Anti-fgf19 antibodies and methods using same
|
|
EP2039766A4
(en)
*
|
2006-06-05 |
2010-06-16 |
Univ Hiroshima |
Immunocompetent cell with anti-CD38 antibody on its surface
|
|
EP1918376A1
(en)
*
|
2006-11-03 |
2008-05-07 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
FGFR4 promotes cancer cell resistance in response to chemotherapeutic drugs
|
|
SI2550972T1
(en)
*
|
2007-04-02 |
2018-05-31 |
Genentech, Inc. |
An antibody called Klotho-beta agonist for use in the treatment of diabetes mellitus or insulin resistance
|
|
EP2188310B1
(en)
|
2007-08-03 |
2017-02-08 |
Genentech, Inc. |
Humanized anti-fgf19 antagonists and methods using same
|
|
US20090309617A1
(en)
*
|
2007-08-24 |
2009-12-17 |
Ye Fang |
Biosensor antibody functional mapping
|
|
US20090226459A1
(en)
*
|
2008-01-29 |
2009-09-10 |
Cold Spring Harbor Laboratory |
Role of fgf-19 in cancer diagnosis and treatment
|
|
WO2009134204A1
(en)
*
|
2008-04-30 |
2009-11-05 |
Forskarpatent I Syd Ab |
RESTORATION OF ESTROGEN RECEPTOR-α ACTIVITY
|
|
AU2009271401A1
(en)
*
|
2008-06-16 |
2010-01-21 |
Immunogen Inc. |
Novel synergistic effects
|
|
FR2933702A1
(fr)
*
|
2008-07-08 |
2010-01-15 |
Sanofi Aventis |
Antagonistes specifiques du recepteur fgf-r4
|
|
WO2010006214A1
(en)
*
|
2008-07-09 |
2010-01-14 |
Ambrx, Inc. |
Fgf-21 neutralizing antibodies and their uses
|
|
BRPI0916904A2
(pt)
|
2008-08-04 |
2016-10-11 |
Fiveprime Therapeutics Inc |
polipeptídeos, moléculares de fusão ecd fgfr4, composições farmacêuticas, polinucleotídio e métodos de tratamento de desordem angiogênica, câncer em paciente e degeneração macular em paciente e respectivos usos
|
|
US20100092470A1
(en)
*
|
2008-09-22 |
2010-04-15 |
Icb International, Inc. |
Antibodies, analogs and uses thereof
|
|
US20100136584A1
(en)
*
|
2008-09-22 |
2010-06-03 |
Icb International, Inc. |
Methods for using antibodies and analogs thereof
|
|
EP2478003A4
(en)
|
2009-09-15 |
2013-05-29 |
Five Prime Therapeutics Inc |
HAIR GROWTH METHODS USING THE EXTRACELLULAR DOMAINS OF FGFR4
|
|
MX2012004303A
(es)
*
|
2009-10-15 |
2012-06-25 |
Genentech Inc |
Factores de crecimiento de fibroblasto quimericos con especificacion de receptor alterada.
|
|
PL2498799T3
(pl)
|
2009-11-13 |
2017-03-31 |
Five Prime Therapeutics, Inc. |
Zastosowanie białek domeny zewnątrzkomórkowej FGFR1 do leczenia nowotworów charakteryzujących się mutacjami aktywującymi zależnymi od ligandów w FGFR2
|
|
JP6184695B2
(ja)
|
2009-12-04 |
2017-08-23 |
ジェネンテック, インコーポレイテッド |
多重特異性抗体、抗体アナログ、組成物、及び方法
|
|
US8685931B2
(en)
|
2009-12-17 |
2014-04-01 |
Five Prime Therapeutics, Inc. |
Hair growth methods using FGFR3 extracellular domains
|
|
JP4881428B2
(ja)
*
|
2009-12-25 |
2012-02-22 |
株式会社東芝 |
電子機器
|
|
US8481038B2
(en)
|
2010-11-15 |
2013-07-09 |
Five Prime Therapeutics, Inc. |
Treatment of cancer with elevated dosages of soluble FGFR1 fusion proteins
|
|
US8951972B2
(en)
|
2010-12-09 |
2015-02-10 |
Five Prime Therapeutics, Inc. |
FGFR1 extracellular domain combination therapies for lung cancer
|
|
KR20190107761A
(ko)
|
2011-03-09 |
2019-09-20 |
셀 시그널링 테크놀러지, 인크. |
모노클로날 항체를 생성하는 방법 및 시약
|
|
EP2723391B1
(en)
*
|
2011-06-24 |
2018-06-13 |
University of Miami |
Fibroblast growth factor receptor inhibition for the treatment of disease
|
|
US10016484B2
(en)
|
2011-11-14 |
2018-07-10 |
Five Prime Therapeutics, Inc. |
Methods of treating lung cancer
|
|
US10112987B2
(en)
|
2012-01-09 |
2018-10-30 |
Icb International, Inc. |
Blood-brain barrier permeable peptide compositions comprising a vab domain of a camelid single domain heavy chain antibody against an amyloid-beta peptide
|
|
US10112988B2
(en)
|
2012-01-09 |
2018-10-30 |
Icb International, Inc. |
Methods of assessing amyloid-beta peptides in the central nervous system by blood-brain barrier permeable peptide compositions comprising a vab domain of a camelid single domain heavy chain antibody against an anti-amyloid-beta peptide
|
|
CA2862424A1
(en)
*
|
2012-01-18 |
2013-07-25 |
Genentech, Inc. |
Methods of using fgf19 modulators
|
|
WO2013167153A1
(en)
*
|
2012-05-09 |
2013-11-14 |
Ganymed Pharmaceuticals Ag |
Antibodies useful in cancer diagnosis
|
|
UA120029C2
(uk)
|
2012-07-13 |
2019-09-25 |
Рош Глікарт Аг |
Спосіб зниження в'язкості біспецифічного антитіла до vegf/ang-2 та застосування такого антитіла для лікування судинних очних захворювань
|
|
HK1209434A1
(en)
|
2012-11-13 |
2016-04-01 |
Astellas Pharma Inc. |
Agents for treatment of claudin expressing cancer diseases
|
|
EP3060563B1
(en)
|
2013-10-25 |
2018-05-02 |
Novartis AG |
Ring-fused bicyclic pyridyl derivatives as fgfr4 inhibitors
|
|
PL3082858T3
(pl)
*
|
2013-12-20 |
2021-09-27 |
Angiobiomed Gmbh |
Środek wiążący adrenomedulinę do zastosowania w terapii nowotworu
|
|
TWI728373B
(zh)
|
2013-12-23 |
2021-05-21 |
美商建南德克公司 |
抗體及使用方法
|
|
PL3200786T3
(pl)
|
2014-10-03 |
2020-03-31 |
Novartis Ag |
Zastosowanie pochodnych pirydylowych o skondensowanym układzie bicyklicznym jako inhibitorów fgfr4
|
|
CN114129709A
(zh)
*
|
2014-10-23 |
2022-03-04 |
恩格姆生物制药公司 |
包含肽变异体的药物组合物及其使用方法
|
|
RU2017134379A
(ru)
|
2015-03-25 |
2019-04-03 |
Новартис Аг |
Формилированные n-гетероциклические производные в качестве ингибиторов fgfr4
|
|
EP3414267B1
(en)
*
|
2016-02-10 |
2023-12-27 |
BioInvent International AB |
Combination of human anti-fgfr4 antibody and sorafenib
|
|
US10813933B2
(en)
*
|
2016-05-17 |
2020-10-27 |
Japanese Foundation For Cancer Research |
Therapeutic agent for lung cancer that has acquired EGFR-TKI resistance
|
|
WO2018055503A1
(en)
|
2016-09-20 |
2018-03-29 |
Novartis Ag |
Combination comprising a pd-1 antagonist and an fgfr4 inhibitor
|
|
PT3534902T
(pt)
|
2016-11-02 |
2022-12-07 |
Novartis Ag |
Combinações de inibidores de fgfr4 e quelantes de ácidos biliares
|
|
EP3514171A1
(en)
*
|
2018-01-18 |
2019-07-24 |
Molecular Cloning Laboratories (MCLAB) LLC |
Long-acting therapeutic fusion proteins
|
|
CN109251983B
(zh)
*
|
2018-08-15 |
2022-03-25 |
深圳市罗湖区人民医院 |
Frs2基因的拷贝数扩增及其应用、检测拷贝数扩增的特异性引物对
|
|
WO2020156539A1
(en)
*
|
2019-02-02 |
2020-08-06 |
Huahui Health Ltd. |
Anti-fgf19 antibodies
|
|
EP3865155B1
(en)
*
|
2020-02-13 |
2022-11-30 |
Orano Med |
Process for site-specific modification of an antibody
|
|
CN116726005A
(zh)
*
|
2022-03-03 |
2023-09-12 |
上海市第六人民医院 |
一种治疗运动损伤的药物及筛选方法和应用
|
|
IL316411A
(en)
|
2022-05-19 |
2024-12-01 |
Tyra Biosciences Inc |
Therapies with PPAR agonists and FGFR4 inhibitors
|
|
EP4509142A1
(en)
|
2023-08-16 |
2025-02-19 |
Ona Therapeutics S.L. |
Fgfr4 as target in cancer treatment
|