NZ569957A - Anti-FGF19 antibodies and methods using same - Google Patents
Anti-FGF19 antibodies and methods using sameInfo
- Publication number
- NZ569957A NZ569957A NZ569957A NZ56995707A NZ569957A NZ 569957 A NZ569957 A NZ 569957A NZ 569957 A NZ569957 A NZ 569957A NZ 56995707 A NZ56995707 A NZ 56995707A NZ 569957 A NZ569957 A NZ 569957A
- Authority
- NZ
- New Zealand
- Prior art keywords
- antibody
- fgf19
- cancer
- expression
- sequence
- Prior art date
Links
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/565—Complementarity determining region [CDR]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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Landscapes
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- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
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| US77231006P | 2006-02-10 | 2006-02-10 | |
| US78060806P | 2006-03-09 | 2006-03-09 | |
| US88586607P | 2007-01-19 | 2007-01-19 | |
| PCT/US2007/061936 WO2007136893A2 (en) | 2006-02-10 | 2007-02-09 | Anti-fgf19 antibodies and methods using same |
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| NZ569957A true NZ569957A (en) | 2012-03-30 |
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| EP (1) | EP1989230B1 (enExample) |
| JP (1) | JP5209505B2 (enExample) |
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| CA (1) | CA2637988A1 (enExample) |
| ES (1) | ES2582652T3 (enExample) |
| NZ (1) | NZ569957A (enExample) |
| TW (1) | TWI388568B (enExample) |
| WO (1) | WO2007136893A2 (enExample) |
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| US6737056B1 (en) * | 1999-01-15 | 2004-05-18 | Genentech, Inc. | Polypeptide variants with altered effector function |
| DE10254601A1 (de) | 2002-11-22 | 2004-06-03 | Ganymed Pharmaceuticals Ag | Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung |
| EP1910542B1 (en) | 2005-07-22 | 2009-12-02 | Five Prime Therapeutics, Inc. | Compositions and methods of treating disease with fgfr fusion proteins |
| CA2637988A1 (en) | 2006-02-10 | 2007-11-29 | Genentech, Inc. | Anti-fgf19 antibodies and methods using same |
| EP2039766A4 (en) * | 2006-06-05 | 2010-06-16 | Univ Hiroshima | Immunocompetent cell with anti-CD38 antibody on its surface |
| EP1918376A1 (en) * | 2006-11-03 | 2008-05-07 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | FGFR4 promotes cancer cell resistance in response to chemotherapeutic drugs |
| SI2550972T1 (en) * | 2007-04-02 | 2018-05-31 | Genentech, Inc. | An antibody called Klotho-beta agonist for use in the treatment of diabetes mellitus or insulin resistance |
| EP2188310B1 (en) | 2007-08-03 | 2017-02-08 | Genentech, Inc. | Humanized anti-fgf19 antagonists and methods using same |
| US20090309617A1 (en) * | 2007-08-24 | 2009-12-17 | Ye Fang | Biosensor antibody functional mapping |
| US20090226459A1 (en) * | 2008-01-29 | 2009-09-10 | Cold Spring Harbor Laboratory | Role of fgf-19 in cancer diagnosis and treatment |
| WO2009134204A1 (en) * | 2008-04-30 | 2009-11-05 | Forskarpatent I Syd Ab | RESTORATION OF ESTROGEN RECEPTOR-α ACTIVITY |
| AU2009271401A1 (en) * | 2008-06-16 | 2010-01-21 | Immunogen Inc. | Novel synergistic effects |
| FR2933702A1 (fr) * | 2008-07-08 | 2010-01-15 | Sanofi Aventis | Antagonistes specifiques du recepteur fgf-r4 |
| WO2010006214A1 (en) * | 2008-07-09 | 2010-01-14 | Ambrx, Inc. | Fgf-21 neutralizing antibodies and their uses |
| BRPI0916904A2 (pt) | 2008-08-04 | 2016-10-11 | Fiveprime Therapeutics Inc | polipeptídeos, moléculares de fusão ecd fgfr4, composições farmacêuticas, polinucleotídio e métodos de tratamento de desordem angiogênica, câncer em paciente e degeneração macular em paciente e respectivos usos |
| US20100092470A1 (en) * | 2008-09-22 | 2010-04-15 | Icb International, Inc. | Antibodies, analogs and uses thereof |
| US20100136584A1 (en) * | 2008-09-22 | 2010-06-03 | Icb International, Inc. | Methods for using antibodies and analogs thereof |
| EP2478003A4 (en) | 2009-09-15 | 2013-05-29 | Five Prime Therapeutics Inc | HAIR GROWTH METHODS USING THE EXTRACELLULAR DOMAINS OF FGFR4 |
| MX2012004303A (es) * | 2009-10-15 | 2012-06-25 | Genentech Inc | Factores de crecimiento de fibroblasto quimericos con especificacion de receptor alterada. |
| PL2498799T3 (pl) | 2009-11-13 | 2017-03-31 | Five Prime Therapeutics, Inc. | Zastosowanie białek domeny zewnątrzkomórkowej FGFR1 do leczenia nowotworów charakteryzujących się mutacjami aktywującymi zależnymi od ligandów w FGFR2 |
| JP6184695B2 (ja) | 2009-12-04 | 2017-08-23 | ジェネンテック, インコーポレイテッド | 多重特異性抗体、抗体アナログ、組成物、及び方法 |
| US8685931B2 (en) | 2009-12-17 | 2014-04-01 | Five Prime Therapeutics, Inc. | Hair growth methods using FGFR3 extracellular domains |
| JP4881428B2 (ja) * | 2009-12-25 | 2012-02-22 | 株式会社東芝 | 電子機器 |
| US8481038B2 (en) | 2010-11-15 | 2013-07-09 | Five Prime Therapeutics, Inc. | Treatment of cancer with elevated dosages of soluble FGFR1 fusion proteins |
| US8951972B2 (en) | 2010-12-09 | 2015-02-10 | Five Prime Therapeutics, Inc. | FGFR1 extracellular domain combination therapies for lung cancer |
| KR20190107761A (ko) | 2011-03-09 | 2019-09-20 | 셀 시그널링 테크놀러지, 인크. | 모노클로날 항체를 생성하는 방법 및 시약 |
| EP2723391B1 (en) * | 2011-06-24 | 2018-06-13 | University of Miami | Fibroblast growth factor receptor inhibition for the treatment of disease |
| US10016484B2 (en) | 2011-11-14 | 2018-07-10 | Five Prime Therapeutics, Inc. | Methods of treating lung cancer |
| US10112987B2 (en) | 2012-01-09 | 2018-10-30 | Icb International, Inc. | Blood-brain barrier permeable peptide compositions comprising a vab domain of a camelid single domain heavy chain antibody against an amyloid-beta peptide |
| US10112988B2 (en) | 2012-01-09 | 2018-10-30 | Icb International, Inc. | Methods of assessing amyloid-beta peptides in the central nervous system by blood-brain barrier permeable peptide compositions comprising a vab domain of a camelid single domain heavy chain antibody against an anti-amyloid-beta peptide |
| CA2862424A1 (en) * | 2012-01-18 | 2013-07-25 | Genentech, Inc. | Methods of using fgf19 modulators |
| WO2013167153A1 (en) * | 2012-05-09 | 2013-11-14 | Ganymed Pharmaceuticals Ag | Antibodies useful in cancer diagnosis |
| UA120029C2 (uk) | 2012-07-13 | 2019-09-25 | Рош Глікарт Аг | Спосіб зниження в'язкості біспецифічного антитіла до vegf/ang-2 та застосування такого антитіла для лікування судинних очних захворювань |
| HK1209434A1 (en) | 2012-11-13 | 2016-04-01 | Astellas Pharma Inc. | Agents for treatment of claudin expressing cancer diseases |
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| CA2637988A1 (en) | 2006-02-10 | 2007-11-29 | Genentech, Inc. | Anti-fgf19 antibodies and methods using same |
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- 2007-02-09 AR ARP070100563A patent/AR059432A1/es not_active Application Discontinuation
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- 2007-02-09 AU AU2007254005A patent/AU2007254005B2/en not_active Ceased
- 2007-02-09 US US11/673,411 patent/US7678373B2/en not_active Expired - Fee Related
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- 2007-02-09 ES ES07797128.1T patent/ES2582652T3/es active Active
- 2007-02-09 TW TW096104900A patent/TWI388568B/zh not_active IP Right Cessation
- 2007-02-09 NZ NZ569957A patent/NZ569957A/en not_active IP Right Cessation
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| AR059432A1 (es) | 2008-04-09 |
| TWI388568B (zh) | 2013-03-11 |
| US7678373B2 (en) | 2010-03-16 |
| US20120128675A1 (en) | 2012-05-24 |
| JP2009525764A (ja) | 2009-07-16 |
| WO2007136893A2 (en) | 2007-11-29 |
| US20070248604A1 (en) | 2007-10-25 |
| TW200808827A (en) | 2008-02-16 |
| CA2637988A1 (en) | 2007-11-29 |
| HK1120273A1 (zh) | 2009-03-27 |
| EP1989230A2 (en) | 2008-11-12 |
| US8241633B2 (en) | 2012-08-14 |
| US20100129381A1 (en) | 2010-05-27 |
| JP5209505B2 (ja) | 2013-06-12 |
| WO2007136893A3 (en) | 2008-05-15 |
| AU2007254005B2 (en) | 2012-11-29 |
| US20110086032A1 (en) | 2011-04-14 |
| AU2007254005A1 (en) | 2007-11-29 |
| US8293241B2 (en) | 2012-10-23 |
| EP1989230B1 (en) | 2016-06-01 |
| ES2582652T3 (es) | 2016-09-14 |
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