|
US4331647A
(en)
*
|
1980-03-03 |
1982-05-25 |
Goldenberg Milton David |
Tumor localization and therapy with labeled antibody fragments specific to tumor-associated markers
|
|
US4376110A
(en)
*
|
1980-08-04 |
1983-03-08 |
Hybritech, Incorporated |
Immunometric assays using monoclonal antibodies
|
|
US4411993A
(en)
*
|
1981-04-29 |
1983-10-25 |
Steven Gillis |
Hybridoma antibody which inhibits interleukin 2 activity
|
|
US4427115A
(en)
*
|
1981-10-19 |
1984-01-24 |
Laipply Thomas C |
One piece alcohol preparation device
|
|
USRE32011E
(en)
*
|
1981-12-14 |
1985-10-22 |
Scripps Clinic And Research Foundation |
Ultrapurification of factor VIII using monoclonal antibodies
|
|
US4543439A
(en)
*
|
1982-12-13 |
1985-09-24 |
Massachusetts Institute Of Technology |
Production and use of monoclonal antibodies to phosphotyrosine-containing proteins
|
|
US6054561A
(en)
*
|
1984-02-08 |
2000-04-25 |
Chiron Corporation |
Antigen-binding sites of antibody molecules specific for cancer antigens
|
|
DE3417525C1
(de)
*
|
1984-05-11 |
1986-01-09 |
Matter + Siegmann Ag, Wohlen |
Vorrichtung zur quantitativen und qualitativen Erfassung von kohlenwasserstoffhaltigen Schwebeteilchen in Gasen
|
|
US4902614A
(en)
*
|
1984-12-03 |
1990-02-20 |
Teijin Limited |
Monoclonal antibody to human protein C
|
|
US4987071A
(en)
|
1986-12-03 |
1991-01-22 |
University Patents, Inc. |
RNA ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods
|
|
ATE115999T1
(de)
|
1987-12-15 |
1995-01-15 |
Gene Shears Pty Ltd |
Ribozyme.
|
|
US5223409A
(en)
*
|
1988-09-02 |
1993-06-29 |
Protein Engineering Corp. |
Directed evolution of novel binding proteins
|
|
US5530101A
(en)
*
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
US5549910A
(en)
*
|
1989-03-31 |
1996-08-27 |
The Regents Of The University Of California |
Preparation of liposome and lipid complex compositions
|
|
US5244805A
(en)
|
1989-05-17 |
1993-09-14 |
University Of Georgia Research Foundation, Inc. |
Baculovirus expression vectors
|
|
US5466468A
(en)
|
1990-04-03 |
1995-11-14 |
Ciba-Geigy Corporation |
Parenterally administrable liposome formulation comprising synthetic lipids
|
|
JP3218637B2
(ja)
*
|
1990-07-26 |
2001-10-15 |
大正製薬株式会社 |
安定なリポソーム水懸濁液
|
|
EP0542810A1
(en)
*
|
1990-08-02 |
1993-05-26 |
B.R. Centre Limited |
Methods for the production of proteins with a desired function
|
|
JP2958076B2
(ja)
*
|
1990-08-27 |
1999-10-06 |
株式会社ビタミン研究所 |
遺伝子導入用多重膜リポソーム及び遺伝子捕捉多重膜リポソーム製剤並びにその製法
|
|
US5877397A
(en)
*
|
1990-08-29 |
1999-03-02 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
|
US5698426A
(en)
*
|
1990-09-28 |
1997-12-16 |
Ixsys, Incorporated |
Surface expression libraries of heteromeric receptors
|
|
US5070108A
(en)
*
|
1990-10-12 |
1991-12-03 |
Trustees Of The University Of Pennsylvania |
Methods of treating osteoporosis, increasing bone mineral content and preventing the occurrence of compression fractures in a mammal
|
|
US5399363A
(en)
|
1991-01-25 |
1995-03-21 |
Eastman Kodak Company |
Surface modified anticancer nanoparticles
|
|
US5145684A
(en)
*
|
1991-01-25 |
1992-09-08 |
Sterling Drug Inc. |
Surface modified drug nanoparticles
|
|
US5807683A
(en)
|
1992-11-19 |
1998-09-15 |
Combichem, Inc. |
Combinatorial libraries and methods for their use
|
|
CA2164505A1
(en)
*
|
1993-06-07 |
1994-12-22 |
Phillip W. Berman |
Hiv envelope polypeptides
|
|
US5543158A
(en)
*
|
1993-07-23 |
1996-08-06 |
Massachusetts Institute Of Technology |
Biodegradable injectable nanoparticles
|
|
US5453492A
(en)
*
|
1993-07-28 |
1995-09-26 |
La Jolla Cancer Research Foundation |
60 kDa transforming growth factor-β-binding protein and its use to detect or purify TGF-β
|
|
US5605793A
(en)
*
|
1994-02-17 |
1997-02-25 |
Affymax Technologies N.V. |
Methods for in vitro recombination
|
|
US5837458A
(en)
*
|
1994-02-17 |
1998-11-17 |
Maxygen, Inc. |
Methods and compositions for cellular and metabolic engineering
|
|
US5738996A
(en)
|
1994-06-15 |
1998-04-14 |
Pence, Inc. |
Combinational library composition and method
|
|
US6057421A
(en)
*
|
1994-11-30 |
2000-05-02 |
Immpheron, Inc. |
Variable heavy and light chain regions of murine monoclonal antibody 1F7
|
|
US5723750A
(en)
|
1995-01-12 |
1998-03-03 |
Vanderbilt University |
Transgenic plants expressing disassembly deficient viral coat proteins
|
|
US5795587A
(en)
*
|
1995-01-23 |
1998-08-18 |
University Of Pittsburgh |
Stable lipid-comprising drug delivery complexes and methods for their production
|
|
IE80468B1
(en)
|
1995-04-04 |
1998-07-29 |
Elan Corp Plc |
Controlled release biodegradable nanoparticles containing insulin
|
|
CA2220912A1
(en)
*
|
1995-06-05 |
1996-12-12 |
Gregg A. Hastings |
Human ccn-like growth factor
|
|
US5738868A
(en)
*
|
1995-07-18 |
1998-04-14 |
Lipogenics Ltd. |
Liposome compositions and kits therefor
|
|
DK0912738T3
(da)
*
|
1996-05-22 |
2008-11-17 |
Viventia Biotech Inc |
Antigen-bindende-fragmenter der specifikt detekterer cancerceller, nukleotider der koder fragmenterne og anvendelse deraf til profylakse og detektion af cancere
|
|
US6133426A
(en)
*
|
1997-02-21 |
2000-10-17 |
Genentech, Inc. |
Humanized anti-IL-8 monoclonal antibodies
|
|
WO1998046588A2
(en)
*
|
1997-04-11 |
1998-10-22 |
Neorx Corporation |
Compounds and therapies for the prevention of vascular and non-vascular pathologies
|
|
US6278039B1
(en)
|
1997-05-28 |
2001-08-21 |
Axys Pharmaceuticals, Inc. |
C. elegans deletion mutants
|
|
EP0985039B1
(en)
*
|
1997-06-12 |
2008-02-20 |
Novartis International Pharmaceutical Ltd. |
Artificial antibody polypeptides
|
|
US6815201B2
(en)
*
|
1997-09-08 |
2004-11-09 |
The Public Health Research Institute Of The City Of New York, Inc. |
HIV-1 gp120 V1/V2 domain epitopes capable of generating neutralizing antibodies
|
|
US6251588B1
(en)
|
1998-02-10 |
2001-06-26 |
Agilent Technologies, Inc. |
Method for evaluating oligonucleotide probe sequences
|
|
GB9818881D0
(en)
*
|
1998-08-28 |
1998-10-21 |
Glaxo Group Ltd |
Compounds
|
|
US6544485B1
(en)
*
|
2001-01-29 |
2003-04-08 |
Sharper Image Corporation |
Electro-kinetic device with enhanced anti-microorganism capability
|
|
DK2261335T3
(en)
*
|
1998-11-27 |
2017-09-18 |
Ucb Pharma Sa |
Compositions and Methods for Increasing Bone Mineralization
|
|
US20040009535A1
(en)
*
|
1998-11-27 |
2004-01-15 |
Celltech R&D, Inc. |
Compositions and methods for increasing bone mineralization
|
|
US6110462A
(en)
|
1999-03-03 |
2000-08-29 |
The Scripps Research Institute |
Enzymatic DNA molecules that contain modified nucleotides
|
|
CA2410912A1
(en)
*
|
2000-06-01 |
2001-12-06 |
Amgen, Inc. |
Cystine-knot polypeptides: cloaked-2 molecules and uses thereof
|
|
US20030133939A1
(en)
*
|
2001-01-17 |
2003-07-17 |
Genecraft, Inc. |
Binding domain-immunoglobulin fusion proteins
|
|
CA2374027A1
(en)
*
|
2001-03-13 |
2002-09-13 |
The Minister Of National Defence |
Cloning, expression, sequencing, and functional enhancement of monoclonal scfv antibody against venezuelan equine encephalitis virus(vee)
|
|
DE10145772A1
(de)
*
|
2001-09-17 |
2003-04-10 |
Bayer Cropscience Ag |
DELTA·1·-Pyrroline
|
|
US7261892B2
(en)
|
2001-11-27 |
2007-08-28 |
Celltech R&D Limited |
Methods for diagnosis and treatment of epithelial-derived cancers
|
|
US20030186915A1
(en)
*
|
2002-02-11 |
2003-10-02 |
Yang Pan |
Regulatory polynucleotides and uses thereof
|
|
WO2003073991A2
(en)
|
2002-03-01 |
2003-09-12 |
Celltech R & D, Inc. |
Methods to increase or decrease bone density
|
|
US7893218B2
(en)
*
|
2003-06-16 |
2011-02-22 |
Stowers Institute For Medical Research |
Antibodies that specifically bind SOST peptides
|
|
AU2003276430A1
(en)
*
|
2002-06-14 |
2003-12-31 |
Stowers Institute For Medical Research |
Wise/sost nucleic acid sequences and amino acid sequences
|
|
JP2006507841A
(ja)
|
2002-11-14 |
2006-03-09 |
ダーマコン， インコーポレイテッド |
機能的ｓｉＲＮＡおよび超機能的ｓｉＲＮＡ
|
|
US7642238B2
(en)
*
|
2002-12-05 |
2010-01-05 |
Shaughnessy John D |
Molecular determinants of myeloma bone disease and uses thereof
|
|
US20040141875A1
(en)
*
|
2003-01-15 |
2004-07-22 |
Rajiv Doshi |
System and method for treating microorganisms within motor vehicle heating, ventilation, and air conditioning units
|
|
PT1608399E
(pt)
*
|
2003-03-14 |
2012-04-13 |
Ucb Mfg Inc |
Complexo de esclerostina e noguina ou cordina, e agentes que modulam a formação do referido complexo
|
|
JP4605799B2
(ja)
|
2003-04-02 |
2011-01-05 |
ダーマコン， インコーポレイテッド |
Ｒｎａ干渉において使用するための修飾ポリヌクレオチド
|
|
NO345763B1
(no)
|
2003-06-16 |
2021-07-19 |
Celltech R&D Inc |
Immunogen og antistoffer spesifikke for sklerostin, samt farmasøytiske preparater for å øke benmineralisering.
|
|
US8461155B2
(en)
*
|
2003-09-22 |
2013-06-11 |
University Of Connecticut |
Sclerostin and the inhibition of WNT signaling and bone formation
|
|
EP2123759B1
(en)
|
2004-02-06 |
2014-01-15 |
Thermo Fisher Scientific Biosciences Inc. |
Stabilized RNAS as transfection controls and silencing reagents
|
|
KR101147147B1
(ko)
|
2004-04-01 |
2012-05-25 |
머크 샤프 앤드 돔 코포레이션 |
Ｒｎａ 간섭의 오프 타겟 효과 감소를 위한 변형된폴리뉴클레오타이드
|
|
US8003108B2
(en)
*
|
2005-05-03 |
2011-08-23 |
Amgen Inc. |
Sclerostin epitopes
|
|
US7592429B2
(en)
|
2005-05-03 |
2009-09-22 |
Ucb Sa |
Sclerostin-binding antibody
|
|
US7744874B2
(en)
*
|
2007-03-20 |
2010-06-29 |
Eli Lilly And Company |
Anti-sclerostin antibodies
|
|
CL2008002775A1
(es)
*
|
2007-09-17 |
2008-11-07 |
Amgen Inc |
Uso de un agente de unión a esclerostina para inhibir la resorción ósea.
|