BRPI0819688A2 - Processo para tratamento de fratura óssea com anticorpos anti-esclerostina. - Google Patents
Processo para tratamento de fratura óssea com anticorpos anti-esclerostina.Info
- Publication number
- BRPI0819688A2 BRPI0819688A2 BRPI0819688-5A BRPI0819688A BRPI0819688A2 BR PI0819688 A2 BRPI0819688 A2 BR PI0819688A2 BR PI0819688 A BRPI0819688 A BR PI0819688A BR PI0819688 A2 BRPI0819688 A2 BR PI0819688A2
- Authority
- BR
- Brazil
- Prior art keywords
- bone fracture
- treating bone
- sclerostin antibodies
- sclerostin
- antibodies
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1391707P | 2007-12-14 | 2007-12-14 | |
PCT/US2008/086864 WO2009079471A1 (en) | 2007-12-14 | 2008-12-15 | Method for treating bone fracture with anti-sclerostin antibodies |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0819688A2 true BRPI0819688A2 (pt) | 2015-06-16 |
Family
ID=40394322
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0819688-5A BRPI0819688A2 (pt) | 2007-12-14 | 2008-12-15 | Processo para tratamento de fratura óssea com anticorpos anti-esclerostina. |
Country Status (11)
Country | Link |
---|---|
US (1) | US20110044978A1 (pt) |
EP (2) | EP2628486A3 (pt) |
JP (1) | JP2011506483A (pt) |
KR (1) | KR20100101656A (pt) |
CN (1) | CN101896201A (pt) |
AU (1) | AU2008338464A1 (pt) |
BR (1) | BRPI0819688A2 (pt) |
CA (1) | CA2707400A1 (pt) |
EA (1) | EA201070740A1 (pt) |
MX (1) | MX2010006519A (pt) |
WO (1) | WO2009079471A1 (pt) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000032773A1 (en) | 1998-11-27 | 2000-06-08 | Darwin Discovery Ltd. | Compositions and methods for increasing bone mineralization |
JP4688802B2 (ja) | 2003-06-16 | 2011-05-25 | セルテック アール アンド ディー, インコーポレイテッド | 骨の鉱化作用を増大させるためのスクレロスチンに特異的な抗体および方法 |
US7592429B2 (en) | 2005-05-03 | 2009-09-22 | Ucb Sa | Sclerostin-binding antibody |
US8003108B2 (en) | 2005-05-03 | 2011-08-23 | Amgen Inc. | Sclerostin epitopes |
CL2008002775A1 (es) | 2007-09-17 | 2008-11-07 | Amgen Inc | Uso de un agente de unión a esclerostina para inhibir la resorción ósea. |
TWI489993B (zh) | 2007-10-12 | 2015-07-01 | Novartis Ag | 骨硬化素(sclerostin)抗體組合物及使用方法 |
SG185465A1 (en) | 2010-05-14 | 2012-12-28 | Amgen Inc | High concentration antibody formulations |
KR20180129991A (ko) | 2010-11-05 | 2018-12-05 | 노파르티스 아게 | Il-17 길항제를 사용한 류마티스성 관절염의 치료 방법 |
EA201391248A1 (ru) | 2011-03-01 | 2014-05-30 | Эмджен Инк. | Биспецифические связывающие агенты |
EA029956B1 (ru) | 2011-03-25 | 2018-06-29 | Эмджен Инк. | Кристаллы антител против склеростина и составы на их основе |
EP2702408A1 (en) | 2011-04-29 | 2014-03-05 | Novartis AG | Methods of treating squamous cell carcinoma related applications |
ES2667554T3 (es) * | 2011-08-04 | 2018-05-11 | Amgen Inc. | Método para el tratamiento de los defectos de espacio óseo |
JP6240075B2 (ja) * | 2011-09-22 | 2017-11-29 | エクセリクシス, インク. | 骨粗しょう症の治療方法 |
BR112014016108A2 (pt) | 2011-12-28 | 2018-09-11 | Amgen Inc | método de tratamento de perda óssea alvelar |
EP3626267A1 (en) * | 2012-07-05 | 2020-03-25 | UCB Pharma, S.A. | Treatment for bone diseases |
UY35148A (es) | 2012-11-21 | 2014-05-30 | Amgen Inc | Immunoglobulinas heterodiméricas |
WO2014118705A1 (en) | 2013-01-31 | 2014-08-07 | Novartis Ag | Methods of treating chronic kidney disease-mineral and bone disorder using sclerostin antagonists |
WO2014155278A2 (en) | 2013-03-26 | 2014-10-02 | Novartis Ag | Methods of treating autoimmune diseases using il-17 antagonists |
MA41142A (fr) | 2014-12-12 | 2017-10-17 | Amgen Inc | Anticorps anti-sclérostine et utilisation de ceux-ci pour traiter des affections osseuses en tant qu'élements du protocole de traitement |
WO2016145961A1 (zh) * | 2015-03-13 | 2016-09-22 | 江苏恒瑞医药股份有限公司 | 抗硬骨素抗体、其抗原结合片段及其医药用途 |
CN105581795A (zh) * | 2016-02-26 | 2016-05-18 | 金哲 | 一种利用磁共振成像监测骨折愈合及研究相关病理生理过程的骨折固定动物模型及其应用 |
GB201604124D0 (en) | 2016-03-10 | 2016-04-27 | Ucb Biopharma Sprl | Pharmaceutical formulation |
JP2020502218A (ja) | 2016-12-21 | 2020-01-23 | メレオ バイオファーマ 3 リミテッド | 骨形成不全症の処置における抗スクレロスチン抗体の使用 |
MX2020010092A (es) | 2018-03-30 | 2020-10-28 | Amgen Inc | Variantes de anticuerpo c-terminales. |
CN110862969B (zh) * | 2019-11-28 | 2021-08-24 | 扬州大学 | 分泌抗cfp-10抗体的杂交瘤细胞株、其抗体及其应用 |
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US7592429B2 (en) * | 2005-05-03 | 2009-09-22 | Ucb Sa | Sclerostin-binding antibody |
US8003108B2 (en) | 2005-05-03 | 2011-08-23 | Amgen Inc. | Sclerostin epitopes |
BRPI0809026A2 (pt) * | 2007-03-20 | 2014-09-23 | Lilly Co Eli | Anticorpos antiesclerotina |
CL2008002775A1 (es) * | 2007-09-17 | 2008-11-07 | Amgen Inc | Uso de un agente de unión a esclerostina para inhibir la resorción ósea. |
-
2008
- 2008-12-15 WO PCT/US2008/086864 patent/WO2009079471A1/en active Application Filing
- 2008-12-15 AU AU2008338464A patent/AU2008338464A1/en not_active Abandoned
- 2008-12-15 CA CA2707400A patent/CA2707400A1/en not_active Abandoned
- 2008-12-15 JP JP2010538229A patent/JP2011506483A/ja active Pending
- 2008-12-15 MX MX2010006519A patent/MX2010006519A/es not_active Application Discontinuation
- 2008-12-15 EP EP13167081.2A patent/EP2628486A3/en not_active Withdrawn
- 2008-12-15 BR BRPI0819688-5A patent/BRPI0819688A2/pt not_active IP Right Cessation
- 2008-12-15 EA EA201070740A patent/EA201070740A1/ru unknown
- 2008-12-15 CN CN2008801201477A patent/CN101896201A/zh active Pending
- 2008-12-15 EP EP08863303A patent/EP2227256A1/en not_active Ceased
- 2008-12-15 KR KR1020107015484A patent/KR20100101656A/ko not_active Application Discontinuation
- 2008-12-15 US US12/811,171 patent/US20110044978A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CN101896201A (zh) | 2010-11-24 |
JP2011506483A (ja) | 2011-03-03 |
EP2628486A2 (en) | 2013-08-21 |
EP2227256A1 (en) | 2010-09-15 |
EA201070740A1 (ru) | 2010-12-30 |
US20110044978A1 (en) | 2011-02-24 |
WO2009079471A1 (en) | 2009-06-25 |
KR20100101656A (ko) | 2010-09-17 |
AU2008338464A1 (en) | 2009-06-25 |
MX2010006519A (es) | 2010-10-15 |
CA2707400A1 (en) | 2009-06-25 |
EP2628486A3 (en) | 2013-10-30 |
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Legal Events
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B08F | Application fees: application dismissed [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 6A E 7A ANUIDADES. |
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B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |