JP2019523295A5 - - Google Patents
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- JP2019523295A5 JP2019523295A5 JP2019517209A JP2019517209A JP2019523295A5 JP 2019523295 A5 JP2019523295 A5 JP 2019523295A5 JP 2019517209 A JP2019517209 A JP 2019517209A JP 2019517209 A JP2019517209 A JP 2019517209A JP 2019523295 A5 JP2019523295 A5 JP 2019523295A5
- Authority
- JP
- Japan
- Prior art keywords
- myostatin
- pharmaceutical composition
- smn
- sma
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662349596P | 2016-06-13 | 2016-06-13 | |
| US62/349,596 | 2016-06-13 | ||
| US201762470157P | 2017-03-10 | 2017-03-10 | |
| US62/470,157 | 2017-03-10 | ||
| US201762486934P | 2017-04-18 | 2017-04-18 | |
| US62/486,934 | 2017-04-18 | ||
| US201762511702P | 2017-05-26 | 2017-05-26 | |
| US62/511,702 | 2017-05-26 | ||
| US201762512254P | 2017-05-30 | 2017-05-30 | |
| US62/512,254 | 2017-05-30 | ||
| PCT/US2017/037332 WO2017218592A1 (en) | 2016-06-13 | 2017-06-13 | Use of myostatin inhibitors and combination therapies |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021000367A Division JP7161554B2 (ja) | 2016-06-13 | 2021-01-05 | ミオスタチン阻害剤の使用および併用療法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019523295A JP2019523295A (ja) | 2019-08-22 |
| JP2019523295A5 true JP2019523295A5 (enExample) | 2020-07-16 |
| JP6823167B2 JP6823167B2 (ja) | 2021-01-27 |
Family
ID=59093642
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019517209A Active JP6823167B2 (ja) | 2016-06-13 | 2017-06-13 | ミオスタチン阻害剤の使用および併用療法 |
| JP2021000367A Active JP7161554B2 (ja) | 2016-06-13 | 2021-01-05 | ミオスタチン阻害剤の使用および併用療法 |
| JP2022064360A Active JP7344337B2 (ja) | 2016-06-13 | 2022-04-08 | ミオスタチン阻害剤の使用および併用療法 |
| JP2023142275A Pending JP2023164920A (ja) | 2016-06-13 | 2023-09-01 | ミオスタチン阻害剤の使用および併用療法 |
| JP2025136177A Pending JP2025183233A (ja) | 2016-06-13 | 2025-08-19 | ミオスタチン阻害剤の使用および併用療法 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021000367A Active JP7161554B2 (ja) | 2016-06-13 | 2021-01-05 | ミオスタチン阻害剤の使用および併用療法 |
| JP2022064360A Active JP7344337B2 (ja) | 2016-06-13 | 2022-04-08 | ミオスタチン阻害剤の使用および併用療法 |
| JP2023142275A Pending JP2023164920A (ja) | 2016-06-13 | 2023-09-01 | ミオスタチン阻害剤の使用および併用療法 |
| JP2025136177A Pending JP2025183233A (ja) | 2016-06-13 | 2025-08-19 | ミオスタチン阻害剤の使用および併用療法 |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US10946036B2 (enExample) |
| EP (3) | EP3785728A3 (enExample) |
| JP (5) | JP6823167B2 (enExample) |
| KR (4) | KR102271635B1 (enExample) |
| AU (4) | AU2017283546C1 (enExample) |
| CL (1) | CL2018003588A1 (enExample) |
| CY (1) | CY1123678T1 (enExample) |
| DK (2) | DK4218804T3 (enExample) |
| ES (1) | ES2830440T3 (enExample) |
| FI (1) | FI4218804T3 (enExample) |
| HR (1) | HRP20201764T1 (enExample) |
| HU (1) | HUE051480T2 (enExample) |
| IL (2) | IL301468A (enExample) |
| LT (1) | LT3368069T (enExample) |
| MY (2) | MY199499A (enExample) |
| NZ (3) | NZ789250A (enExample) |
| PE (1) | PE20190205A1 (enExample) |
| PT (1) | PT3368069T (enExample) |
| RS (1) | RS61090B1 (enExample) |
| SI (1) | SI3368069T1 (enExample) |
| SM (1) | SMT202000598T1 (enExample) |
| WO (1) | WO2017218592A1 (enExample) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IN2014DN10515A (enExample) | 2006-03-31 | 2015-08-21 | Chugai Pharmaceutical Co Ltd | |
| MX336725B (es) | 2007-09-26 | 2016-01-28 | Chugai Pharmaceutical Co Ltd | Metodo de modificacion del punto isoelectrico de anticuerpos medinate la sustitucion de aminoacidos en region de determinacion de complementariedad (cdr). |
| TWI700293B (zh) | 2008-04-11 | 2020-08-01 | 日商中外製藥股份有限公司 | 重複結合複數個抗原的抗體 |
| KR102568454B1 (ko) | 2010-11-30 | 2023-08-18 | 추가이 세이야쿠 가부시키가이샤 | 복수 분자의 항원에 반복해서 결합하는 항원 결합 분자 |
| EP3597747B1 (en) | 2012-08-24 | 2023-03-15 | Chugai Seiyaku Kabushiki Kaisha | Mouse fcgammarii-specific fc antibody |
| AU2014250434B2 (en) | 2013-04-02 | 2019-08-08 | Chugai Seiyaku Kabushiki Kaisha | Fc region variant |
| EP3215175A4 (en) | 2014-11-06 | 2018-06-27 | Scholar Rock, Inc. | Anti-pro/latent-myostatin antibodies and uses thereof |
| TWI656133B (zh) | 2014-12-19 | 2019-04-11 | 日商中外製藥股份有限公司 | 抗肌抑素之抗體、含變異Ｆｃ區域之多胜肽及使用方法 |
| WO2016125495A1 (en) | 2015-02-05 | 2016-08-11 | Chugai Seiyaku Kabushiki Kaisha | Antibodies comprising an ion concentration dependent antigen-binding domain, fc region variants, il-8-binding antibodies, and uses therof |
| IL305148A (en) | 2015-09-15 | 2023-10-01 | Scholar Rock Inc | Anti-pro/hidden myostatin antibodies and their uses |
| WO2017110981A1 (en) | 2015-12-25 | 2017-06-29 | Chugai Seiyaku Kabushiki Kaisha | Anti-myostatin antibodies and methods of use |
| JP2019504064A (ja) | 2016-01-08 | 2019-02-14 | スカラー ロック インコーポレイテッドＳｃｈｏｌａｒ Ｒｏｃｋ，Ｉｎｃ． | 抗プロ／潜在型ミオスタチン抗体およびその使用方法 |
| EP3785728A3 (en) | 2016-06-13 | 2021-04-28 | Scholar Rock, Inc. | Use of myostatin inhibitors and combination therapies |
| KR102306744B1 (ko) * | 2016-06-17 | 2021-09-28 | 추가이 세이야쿠 가부시키가이샤 | 항-마이오스타틴 항체 및 사용 방법 |
| CN109689099B (zh) | 2016-08-05 | 2023-02-28 | 中外制药株式会社 | 用于预防或治疗il-8相关疾病的组合物 |
| JOP20190085A1 (ar) | 2016-10-20 | 2019-04-17 | Biogen Ma Inc | طرق علاج الضمور العضلي ومرض العظام باستخدام بروتينات احتجاز مركب ترابطي actriib هجين حديثة |
| US11857599B2 (en) | 2017-04-03 | 2024-01-02 | Acceleron Pharma Inc. | Compositions and methods for treating spinal muscular atrophy |
| RU2020105929A (ru) | 2017-08-04 | 2021-09-06 | Скайхоук Терапьютикс, Инк. | Способы и композиции для модулирования сплайсинга |
| WO2019170930A1 (es) * | 2018-03-09 | 2019-09-12 | Universitat De Lleida | Tratamiento para la atrofia muscular espinal |
| CN112334157A (zh) * | 2018-04-17 | 2021-02-05 | 应用干细胞有限公司 | 治疗脊髓肌萎缩症的组合物和方法 |
| TW202043267A (zh) | 2019-01-30 | 2020-12-01 | 美商供石公司 | TGFβ之LTBP複合物專一性抑制劑及其用途 |
| JP7603592B2 (ja) | 2019-02-05 | 2024-12-20 | スカイホーク・セラピューティクス・インコーポレーテッド | スプライシングを調節するための方法および組成物 |
| EP3920926A4 (en) | 2019-02-05 | 2022-10-19 | Skyhawk Therapeutics, Inc. | Methods and compositions for modulating splicing |
| CN119638696A (zh) | 2019-02-06 | 2025-03-18 | 斯基霍克疗法公司 | 用于调节剪接的方法和组合物 |
| WO2020163544A1 (en) | 2019-02-06 | 2020-08-13 | Skyhawk Therapeutics, Inc. | Methods and compositions for modulating splicing |
| CN113993452A (zh) * | 2019-06-19 | 2022-01-28 | 豪夫迈·罗氏有限公司 | 数字生物标志物 |
| JP2022537266A (ja) * | 2019-06-19 | 2022-08-25 | エフ．ホフマン－ラ ロシュ アーゲー | デジタルバイオマーカー |
| US11918570B2 (en) | 2020-04-13 | 2024-03-05 | The Research Foundation For The State University Of New York | Method of treatment for prevention of glucocorticoid toxicity and/or enhancement of muscle regeneration via neutrophil elastase inhibition |
| CA3193909A1 (en) | 2020-10-26 | 2022-05-05 | George NOMIKOS | Use of anti-pro/latent myostatin antibody for treating spinal muscular atrophy |
| MX2023014840A (es) | 2021-06-23 | 2024-02-12 | Scholar Rock Inc | Un inhibidor de la vía de la miostatina en combinación con un activador de la vía de la glp-1 para su uso en el tratamiento de trastornos metabólicos. |
| EP4370148A1 (en) | 2021-07-14 | 2024-05-22 | Scholar Rock, Inc. | Ltbp complex-specific inhibitors of tgf beta1 and uses thereof |
| EP4426306A1 (en) * | 2021-10-06 | 2024-09-11 | F. Hoffmann-La Roche AG | Novel combined administration |
| EP4518970B1 (en) * | 2022-05-04 | 2026-03-25 | Scholar Rock, Inc. | Use of myostatin inhibitor for treating spinal muscular atrophy |
| CN120677175A (zh) | 2022-12-22 | 2025-09-19 | 供石公司 | 肌生成抑制蛋白活化的选择性和强效抑制剂 |
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| JP6877357B2 (ja) * | 2015-04-15 | 2021-05-26 | リジェネロン・ファーマシューティカルズ・インコーポレイテッドＲｅｇｅｎｅｒｏｎ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． | Ｇｄｆ８阻害剤を用いて、強度及び機能を増加させる方法 |
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| JP2019504064A (ja) | 2016-01-08 | 2019-02-14 | スカラー ロック インコーポレイテッドＳｃｈｏｌａｒ Ｒｏｃｋ，Ｉｎｃ． | 抗プロ／潜在型ミオスタチン抗体およびその使用方法 |
| EP3785728A3 (en) | 2016-06-13 | 2021-04-28 | Scholar Rock, Inc. | Use of myostatin inhibitors and combination therapies |
| JOP20190152A1 (ar) | 2016-12-21 | 2019-06-20 | Novartis Ag | مضادات الميوستاتين، الآكتيفين أو مستقبلات الآكتيفين للاستخدام في علاج السمنة والحالات ذات الصلة |
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2017
- 2017-06-13 EP EP20179533.3A patent/EP3785728A3/en active Pending
- 2017-06-13 SM SM20200598T patent/SMT202000598T1/it unknown
- 2017-06-13 RS RS20201327A patent/RS61090B1/sr unknown
- 2017-06-13 KR KR1020197000822A patent/KR102271635B1/ko active Active
- 2017-06-13 FI FIEP23157280.1T patent/FI4218804T3/fi active
- 2017-06-13 AU AU2017283546A patent/AU2017283546C1/en active Active
- 2017-06-13 NZ NZ789250A patent/NZ789250A/en unknown
- 2017-06-13 EP EP23157280.1A patent/EP4218804B1/en active Active
- 2017-06-13 US US16/308,007 patent/US10946036B2/en active Active
- 2017-06-13 ES ES17732001T patent/ES2830440T3/es active Active
- 2017-06-13 KR KR1020217019817A patent/KR20210082548A/ko not_active Ceased
- 2017-06-13 KR KR1020237005734A patent/KR20230028813A/ko not_active Ceased
- 2017-06-13 IL IL301468A patent/IL301468A/en unknown
- 2017-06-13 NZ NZ789269A patent/NZ789269A/en unknown
- 2017-06-13 SI SI201730485T patent/SI3368069T1/sl unknown
- 2017-06-13 LT LTEP17732001.7T patent/LT3368069T/lt unknown
- 2017-06-13 PT PT177320017T patent/PT3368069T/pt unknown
- 2017-06-13 HU HUE17732001A patent/HUE051480T2/hu unknown
- 2017-06-13 MY MYPI2020004682A patent/MY199499A/en unknown
- 2017-06-13 PE PE2018003207A patent/PE20190205A1/es unknown
- 2017-06-13 WO PCT/US2017/037332 patent/WO2017218592A1/en not_active Ceased
- 2017-06-13 DK DK23157280.1T patent/DK4218804T3/da active
- 2017-06-13 EP EP17732001.7A patent/EP3368069B1/en active Active
- 2017-06-13 KR KR1020237042111A patent/KR20230169484A/ko not_active Ceased
- 2017-06-13 HR HRP20201764TT patent/HRP20201764T1/hr unknown
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2018
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2020
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2021
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