JP2019523295A5 - - Google Patents
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- JP2019523295A5 JP2019523295A5 JP2019517209A JP2019517209A JP2019523295A5 JP 2019523295 A5 JP2019523295 A5 JP 2019523295A5 JP 2019517209 A JP2019517209 A JP 2019517209A JP 2019517209 A JP2019517209 A JP 2019517209A JP 2019523295 A5 JP2019523295 A5 JP 2019523295A5
- Authority
- JP
- Japan
- Prior art keywords
- myostatin
- pharmaceutical composition
- smn
- sma
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662349596P | 2016-06-13 | 2016-06-13 | |
| US62/349,596 | 2016-06-13 | ||
| US201762470157P | 2017-03-10 | 2017-03-10 | |
| US62/470,157 | 2017-03-10 | ||
| US201762486934P | 2017-04-18 | 2017-04-18 | |
| US62/486,934 | 2017-04-18 | ||
| US201762511702P | 2017-05-26 | 2017-05-26 | |
| US62/511,702 | 2017-05-26 | ||
| US201762512254P | 2017-05-30 | 2017-05-30 | |
| US62/512,254 | 2017-05-30 | ||
| PCT/US2017/037332 WO2017218592A1 (en) | 2016-06-13 | 2017-06-13 | Use of myostatin inhibitors and combination therapies |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021000367A Division JP7161554B2 (ja) | 2016-06-13 | 2021-01-05 | ミオスタチン阻害剤の使用および併用療法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019523295A JP2019523295A (ja) | 2019-08-22 |
| JP2019523295A5 true JP2019523295A5 (enExample) | 2020-07-16 |
| JP6823167B2 JP6823167B2 (ja) | 2021-01-27 |
Family
ID=59093642
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019517209A Active JP6823167B2 (ja) | 2016-06-13 | 2017-06-13 | ミオスタチン阻害剤の使用および併用療法 |
| JP2021000367A Active JP7161554B2 (ja) | 2016-06-13 | 2021-01-05 | ミオスタチン阻害剤の使用および併用療法 |
| JP2022064360A Active JP7344337B2 (ja) | 2016-06-13 | 2022-04-08 | ミオスタチン阻害剤の使用および併用療法 |
| JP2023142275A Pending JP2023164920A (ja) | 2016-06-13 | 2023-09-01 | ミオスタチン阻害剤の使用および併用療法 |
| JP2025136177A Pending JP2025183233A (ja) | 2016-06-13 | 2025-08-19 | ミオスタチン阻害剤の使用および併用療法 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021000367A Active JP7161554B2 (ja) | 2016-06-13 | 2021-01-05 | ミオスタチン阻害剤の使用および併用療法 |
| JP2022064360A Active JP7344337B2 (ja) | 2016-06-13 | 2022-04-08 | ミオスタチン阻害剤の使用および併用療法 |
| JP2023142275A Pending JP2023164920A (ja) | 2016-06-13 | 2023-09-01 | ミオスタチン阻害剤の使用および併用療法 |
| JP2025136177A Pending JP2025183233A (ja) | 2016-06-13 | 2025-08-19 | ミオスタチン阻害剤の使用および併用療法 |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US10946036B2 (enExample) |
| EP (3) | EP3368069B1 (enExample) |
| JP (5) | JP6823167B2 (enExample) |
| KR (5) | KR20230169484A (enExample) |
| AU (4) | AU2017283546C1 (enExample) |
| CL (1) | CL2018003588A1 (enExample) |
| CY (1) | CY1123678T1 (enExample) |
| DK (2) | DK4218804T3 (enExample) |
| ES (2) | ES3067719T3 (enExample) |
| FI (1) | FI4218804T3 (enExample) |
| HR (2) | HRP20201764T1 (enExample) |
| HU (1) | HUE051480T2 (enExample) |
| IL (3) | IL326484A (enExample) |
| LT (2) | LT3368069T (enExample) |
| MY (2) | MY185614A (enExample) |
| PE (1) | PE20190205A1 (enExample) |
| PL (1) | PL4218804T3 (enExample) |
| PT (2) | PT4218804T (enExample) |
| RS (2) | RS61090B1 (enExample) |
| SI (2) | SI4218804T1 (enExample) |
| SM (1) | SMT202000598T1 (enExample) |
| WO (1) | WO2017218592A1 (enExample) |
Families Citing this family (42)
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|---|---|---|---|---|
| EP4793360A2 (en) | 2006-03-31 | 2026-08-19 | Chugai Seiyaku Kabushiki Kaisha | Methods for controlling blood pharmacokinetics of antibodies |
| EP3127921A1 (en) | 2007-09-26 | 2017-02-08 | Chugai Seiyaku Kabushiki Kaisha | Method of modifying isoelectric point of antibody via amino acid substition in cdr |
| TW201920257A (zh) | 2008-04-11 | 2019-06-01 | 日商中外製藥股份有限公司 | 重複結合複數個抗原的抗原結合分子 |
| TWI654203B (zh) | 2010-11-30 | 2019-03-21 | Chugai Seiyaku Kabushiki Kaisha | 具有鈣依存性的抗原結合能力之抗體 |
| CA2865158C (en) | 2012-02-24 | 2022-11-01 | Chugai Seiyaku Kabushiki Kaisha | Antigen-binding molecule for promoting disappearance of antigen via fc.gamma.riib |
| JP6774164B2 (ja) | 2012-08-24 | 2020-10-21 | 中外製薬株式会社 | マウスＦｃγＲＩＩ特異的Ｆｃ抗体 |
| SG11201508170TA (en) | 2013-04-02 | 2015-11-27 | Chugai Pharmaceutical Co Ltd | Fc REGION VARIANT |
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| CN114773469B (zh) | 2015-02-05 | 2025-12-19 | 中外制药株式会社 | 包含离子浓度依赖性的抗原结合结构域的抗体，fc区变体，il-8-结合抗体及其应用 |
| EA038146B1 (ru) | 2015-09-15 | 2021-07-13 | Сколар Рок, Инк. | Антитела к про-/латентному миостатину и их применения |
| EP3394098A4 (en) | 2015-12-25 | 2019-11-13 | Chugai Seiyaku Kabushiki Kaisha | ANTI-MYOSTATIN ANTIBODIES AND METHOD OF USE |
| CN115814077A (zh) | 2016-01-08 | 2023-03-21 | 供石公司 | 抗-原肌生长抑制素/潜伏肌生长抑制素抗体及其使用方法 |
| PL4218804T3 (pl) | 2016-06-13 | 2026-05-25 | Scholar Rock, Inc. | Stosowanie inhibitorów miostatyny i terapii skojarzonych |
| TWI760396B (zh) * | 2016-06-17 | 2022-04-11 | 日商中外製藥股份有限公司 | 抗肌抑素抗體及使用方法 |
| CN116271014A (zh) | 2016-08-05 | 2023-06-23 | 中外制药株式会社 | 用于预防或治疗il-8相关疾病的组合物 |
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| MX2020001425A (es) | 2017-08-04 | 2020-08-06 | Skyhawk Therapeutics Inc | Metodos y composiciones para modular el empalme. |
| WO2019170930A1 (es) * | 2018-03-09 | 2019-09-12 | Universitat De Lleida | Tratamiento para la atrofia muscular espinal |
| CN112334157A (zh) * | 2018-04-17 | 2021-02-05 | 应用干细胞有限公司 | 治疗脊髓肌萎缩症的组合物和方法 |
| SG11202108099WA (en) | 2019-01-30 | 2021-08-30 | Scholar Rock Inc | LTBP COMPLEX-SPECIFIC INHIBITORS OF TGFβ AND USES THEREOF |
| WO2020163248A1 (en) | 2019-02-04 | 2020-08-13 | Skyhawk Therapeutics, Inc. | Methods and compositions for modulating splicing |
| KR102913697B1 (ko) | 2019-02-05 | 2026-01-15 | 스카이호크 테라퓨틱스, 인코포레이티드 | 스플라이싱을 조절하는 방법 및 조성물 |
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| JP2022537266A (ja) * | 2019-06-19 | 2022-08-25 | エフ．ホフマン－ラ ロシュ アーゲー | デジタルバイオマーカー |
| JP7597744B2 (ja) * | 2019-06-19 | 2024-12-10 | エフ． ホフマン－ラ ロシュ アーゲー | デジタルバイオマーカー |
| US11918570B2 (en) | 2020-04-13 | 2024-03-05 | The Research Foundation For The State University Of New York | Method of treatment for prevention of glucocorticoid toxicity and/or enhancement of muscle regeneration via neutrophil elastase inhibition |
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| DK4358995T3 (da) | 2021-06-23 | 2026-02-02 | Scholar Rock Inc | Myostatin-vej-hæmmer i kombination med en glp-1-vej-aktivator til brug ved behandling af metaboliske forstyrrelser |
| EP4370148A1 (en) | 2021-07-14 | 2024-05-22 | Scholar Rock, Inc. | Ltbp complex-specific inhibitors of tgf beta1 and uses thereof |
| KR20240049857A (ko) * | 2021-07-19 | 2024-04-17 | 악셀레론 파마 인코포레이티드 | Actrii 단백질 및 이의 용도 |
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| LT4518970T (lt) * | 2022-05-04 | 2026-04-27 | Scholar Rock, Inc. | Miostatino inhibitoriaus panaudojimas spinalinės raumenų atrofijos gydymui |
| CN120677175A (zh) | 2022-12-22 | 2025-09-19 | 供石公司 | 肌生成抑制蛋白活化的选择性和强效抑制剂 |
| AU2024347940A1 (en) | 2023-09-29 | 2026-04-30 | Peptidream Inc. | Peptide |
| TW202617762A (zh) * | 2024-07-04 | 2026-05-01 | 大陸商江蘇恆瑞醫藥股份有限公司 | 特異性結合潛伏肌生長抑制素的抗原結合分子及其醫藥用途 |
| WO2026147753A1 (en) | 2024-12-30 | 2026-07-09 | Scholar Rock, Inc. | Therapies for muscular dystrophies |
| WO2026152042A1 (en) | 2025-01-10 | 2026-07-16 | Scholar Rock, Inc. | A novel class of musk agonists and uses thereof |
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-
2017
- 2017-06-13 PL PL23157280.1T patent/PL4218804T3/pl unknown
- 2017-06-13 SI SI201731653T patent/SI4218804T1/sl unknown
- 2017-06-13 IL IL326484A patent/IL326484A/en unknown
- 2017-06-13 PT PT231572801T patent/PT4218804T/pt unknown
- 2017-06-13 SM SM20200598T patent/SMT202000598T1/it unknown
- 2017-06-13 LT LTEP17732001.7T patent/LT3368069T/lt unknown
- 2017-06-13 PT PT177320017T patent/PT3368069T/pt unknown
- 2017-06-13 KR KR1020237042111A patent/KR20230169484A/ko not_active Ceased
- 2017-06-13 PE PE2018003207A patent/PE20190205A1/es unknown
- 2017-06-13 HR HRP20201764TT patent/HRP20201764T1/hr unknown
- 2017-06-13 WO PCT/US2017/037332 patent/WO2017218592A1/en not_active Ceased
- 2017-06-13 EP EP17732001.7A patent/EP3368069B1/en not_active Revoked
- 2017-06-13 EP EP23157280.1A patent/EP4218804B1/en active Active
- 2017-06-13 SI SI201730485T patent/SI3368069T1/sl unknown
- 2017-06-13 AU AU2017283546A patent/AU2017283546C1/en active Active
- 2017-06-13 MY MYPI2018002494A patent/MY185614A/en unknown
- 2017-06-13 LT LTEP23157280.1T patent/LT4218804T/lt unknown
- 2017-06-13 EP EP20179533.3A patent/EP3785728A3/en active Pending
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