JP2016094424A5 - - Google Patents
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- Publication number
- JP2016094424A5 JP2016094424A5 JP2015229465A JP2015229465A JP2016094424A5 JP 2016094424 A5 JP2016094424 A5 JP 2016094424A5 JP 2015229465 A JP2015229465 A JP 2015229465A JP 2015229465 A JP2015229465 A JP 2015229465A JP 2016094424 A5 JP2016094424 A5 JP 2016094424A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- region
- amino acid
- acid sequence
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25166809P | 2009-10-14 | 2009-10-14 | |
| US61/251,668 | 2009-10-14 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012534368A Division JP2013508292A (ja) | 2009-10-14 | 2010-10-14 | ＥｐｈＡ３に対する抗体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016094424A JP2016094424A (ja) | 2016-05-26 |
| JP2016094424A5 true JP2016094424A5 (enExample) | 2016-10-06 |
Family
ID=43499991
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012534368A Pending JP2013508292A (ja) | 2009-10-14 | 2010-10-14 | ＥｐｈＡ３に対する抗体 |
| JP2015229465A Pending JP2016094424A (ja) | 2009-10-14 | 2015-11-25 | ＥｐｈＡ３に対する抗体 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012534368A Pending JP2013508292A (ja) | 2009-10-14 | 2010-10-14 | ＥｐｈＡ３に対する抗体 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US8664365B2 (enExample) |
| EP (1) | EP2488554B1 (enExample) |
| JP (2) | JP2013508292A (enExample) |
| CN (1) | CN102666589B (enExample) |
| AU (1) | AU2010313621C1 (enExample) |
| CA (1) | CA2777068C (enExample) |
| DK (1) | DK2488554T3 (enExample) |
| ES (1) | ES2743558T3 (enExample) |
| PL (1) | PL2488554T3 (enExample) |
| PT (1) | PT2488554T (enExample) |
| WO (1) | WO2011053465A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011123819A2 (en) * | 2010-04-01 | 2011-10-06 | Kalobios Pharmaceuticals, Inc. | Epha3 antibodies for the treatment of multiple myeloma |
| WO2011160132A2 (en) * | 2010-06-18 | 2011-12-22 | Kalobios Pharmaceuticals, Inc. | Detection of epha3 as a marker of the presence of a solid tumor |
| AU2012295334A1 (en) | 2011-08-12 | 2013-05-02 | Kalobios Pharmaceuticals, Inc. | Methods of treating hematological proliferative disorders by targeting EphA3 expressed on aberrant vasculature in bone marrow |
| MX374785B (es) | 2013-08-01 | 2025-03-06 | Five Prime Therapeutics Inc | Anticuerpos anti-fgfr2iiib afucosilados. |
| SG10201913538VA (en) | 2015-11-23 | 2020-02-27 | Five Prime Therapeutics Inc | Fgfr2 inhibitors alone or in combination with immune stimulating agents in cancer treatment |
| EP3512883A1 (en) | 2016-09-13 | 2019-07-24 | Humanigen, Inc. | Epha3 antibodies for the treatment of pulmonary fibrosis |
| DK3624837T3 (da) | 2017-05-16 | 2025-09-29 | Five Prime Therapeutics Inc | Anti-fgfr2-antistoffer i kombination med kemoterapeutiske midler til kræftbehandling |
| EP3758751A4 (en) | 2018-02-28 | 2021-11-17 | Wuxi Biologics Ireland Limited. | MONOCLONAL ANTIBODIES AGAINST HUMAN LAG-3, METHOD OF MANUFACTURING AND USING THEREOF |
| US20260055195A1 (en) * | 2019-10-09 | 2026-02-26 | The Council Of The Queensland Institute Of Medical Research | Targeting epha3 and uses thereof |
| EP4054602A4 (en) * | 2019-11-08 | 2023-12-06 | Mayo Foundation for Medical Education and Research | EPHA3 TARGETED CAR-T CELLS FOR TREATING TUMORS |
| US20240025971A1 (en) * | 2020-10-23 | 2024-01-25 | Atreca, Inc. | Antibodies to coronavirus sars-cov-2 |
| CN118055945A (zh) * | 2021-08-06 | 2024-05-17 | 韩国生命工学研究院 | 新型抗epha2嵌合抗原受体和表达其的免疫细胞 |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| JP3101690B2 (ja) | 1987-03-18 | 2000-10-23 | エス・ビィ・２・インコーポレイテッド | 変性抗体の、または変性抗体に関する改良 |
| US5677425A (en) | 1987-09-04 | 1997-10-14 | Celltech Therapeutics Limited | Recombinant antibody |
| ATE278019T1 (de) | 1991-06-21 | 2004-10-15 | Inst Medical W & E Hall | Neuartige rezeptor-typ tyrosinkinase und deren verwendung |
| US5714350A (en) | 1992-03-09 | 1998-02-03 | Protein Design Labs, Inc. | Increasing antibody affinity by altering glycosylation in the immunoglobulin variable region |
| AU4116793A (en) | 1992-04-24 | 1993-11-29 | Board Of Regents, The University Of Texas System | Recombinant production of immunoglobulin-like domains in prokaryotic cells |
| NO175798C (no) | 1992-07-22 | 1994-12-07 | Sinvent As | Fremgangsmåte og anordning til aktiv stöydemping i et lokalt område |
| US5885573A (en) | 1993-06-01 | 1999-03-23 | Arch Development Corporation | Methods and materials for modulation of the immunosuppressive activity and toxicity of monoclonal antibodies |
| US5869046A (en) | 1995-04-14 | 1999-02-09 | Genentech, Inc. | Altered polypeptides with increased half-life |
| US6121022A (en) | 1995-04-14 | 2000-09-19 | Genentech, Inc. | Altered polypeptides with increased half-life |
| US6277375B1 (en) | 1997-03-03 | 2001-08-21 | Board Of Regents, The University Of Texas System | Immunoglobulin-like domains with increased half-lives |
| US6194551B1 (en) | 1998-04-02 | 2001-02-27 | Genentech, Inc. | Polypeptide variants |
| JP4334141B2 (ja) | 1998-04-20 | 2009-09-30 | グリカート バイオテクノロジー アクチェンゲゼルシャフト | 抗体依存性細胞傷害性を改善するための抗体のグリコシル化操作 |
| GB9809951D0 (en) | 1998-05-08 | 1998-07-08 | Univ Cambridge Tech | Binding molecules |
| US6737056B1 (en) | 1999-01-15 | 2004-05-18 | Genentech, Inc. | Polypeptide variants with altered effector function |
| HUP0104865A3 (en) | 1999-01-15 | 2004-07-28 | Genentech Inc | Polypeptide variants with altered effector function |
| EP2275540B1 (en) | 1999-04-09 | 2016-03-23 | Kyowa Hakko Kirin Co., Ltd. | Method for controlling the activity of immunologically functional molecule |
| US7029872B2 (en) | 2000-06-28 | 2006-04-18 | Glycofi, Inc | Methods for producing modified glycoproteins |
| US6946292B2 (en) | 2000-10-06 | 2005-09-20 | Kyowa Hakko Kogyo Co., Ltd. | Cells producing antibody compositions with increased antibody dependent cytotoxic activity |
| EP1355919B1 (en) | 2000-12-12 | 2010-11-24 | MedImmune, LLC | Molecules with extended half-lives, compositions and uses thereof |
| US7317091B2 (en) | 2002-03-01 | 2008-01-08 | Xencor, Inc. | Optimized Fc variants |
| CA2923247A1 (en) | 2002-03-19 | 2003-09-25 | Stichting Dienst Landbouwkundig Onderzoek | Optimizing glycan processing in plants |
| CA2832136C (en) | 2002-09-27 | 2015-11-17 | Xencor | Optimized fc variants and methods for their generation |
| US7981843B2 (en) | 2004-01-20 | 2011-07-19 | Kalobios Pharmaceuticals, Inc. | Antibody specificity transfer using minimal essential binding determinants |
| AU2005277641A1 (en) | 2004-08-16 | 2006-03-02 | Medimmune, Llc | Eph receptor Fc variants with enhanced antibody dependent cell-mediated cytotoxicity activity |
| US8222253B2 (en) * | 2004-10-23 | 2012-07-17 | Case Western Reserve University | Peptide and small molecule agonists of EphA and their uses |
| PL2343380T3 (pl) | 2004-11-16 | 2020-03-31 | Humanigen, Inc. | Wymiana kasety dla regionu zmiennego immunoglobuliny |
| US8211648B2 (en) | 2005-07-22 | 2012-07-03 | Kalobios Pharmaceuticals, Inc. | Secretion of antibodies without signal peptides from bacteria |
| US7846724B2 (en) | 2006-04-11 | 2010-12-07 | Hoffmann-La Roche Inc. | Method for selecting CHO cell for production of glycosylated antibodies |
| WO2008060092A1 (en) | 2006-11-17 | 2008-05-22 | Sang Yun Park | Rotative force generator |
| EP3199180B1 (en) * | 2007-03-08 | 2022-01-05 | Humanigen, Inc. | Epha3 antibodies for the treatment of solid tumors |
| CL2008002782A1 (es) | 2007-09-21 | 2009-07-31 | Genentech Inc | Anticuerpo anti-bv8 neutralizante; composicion que lo comprende; y su uso para tratar tumores en humanos previamente tratados con un antagonista del factor de crecimiento endotelial vascular. |
| US8834870B2 (en) | 2009-03-06 | 2014-09-16 | Kalobios Pharmaceuticals, Inc. | Treatment of leukemias and chronic myeloproliferative diseases with antibodies to EphA3 |
-
2010
- 2010-10-14 AU AU2010313621A patent/AU2010313621C1/en not_active Ceased
- 2010-10-14 CA CA2777068A patent/CA2777068C/en active Active
- 2010-10-14 PL PL10777137T patent/PL2488554T3/pl unknown
- 2010-10-14 US US12/904,953 patent/US8664365B2/en not_active Expired - Fee Related
- 2010-10-14 EP EP10777137.0A patent/EP2488554B1/en active Active
- 2010-10-14 PT PT10777137T patent/PT2488554T/pt unknown
- 2010-10-14 ES ES10777137T patent/ES2743558T3/es active Active
- 2010-10-14 JP JP2012534368A patent/JP2013508292A/ja active Pending
- 2010-10-14 WO PCT/US2010/052725 patent/WO2011053465A1/en not_active Ceased
- 2010-10-14 DK DK10777137.0T patent/DK2488554T3/da active
- 2010-10-14 CN CN201080056618.XA patent/CN102666589B/zh active Active
-
2013
- 2013-12-30 US US14/143,427 patent/US9290571B2/en active Active
-
2015
- 2015-11-25 JP JP2015229465A patent/JP2016094424A/ja active Pending
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