|
ATE102631T1
(de)
|
1988-11-11 |
1994-03-15 |
Medical Res Council |
Klonierung von immunglobulin sequenzen aus den variabelen domaenen.
|
|
US5399346A
(en)
|
1989-06-14 |
1995-03-21 |
The United States Of America As Represented By The Department Of Health And Human Services |
Gene therapy
|
|
SE509359C2
(sv)
|
1989-08-01 |
1999-01-18 |
Cemu Bioteknik Ab |
Användning av stabiliserade protein- eller peptidkonjugat för framställning av ett läkemedel
|
|
EP0542810A1
(en)
|
1990-08-02 |
1993-05-26 |
B.R. Centre Limited |
Methods for the production of proteins with a desired function
|
|
EP0640130B1
(en)
|
1992-05-08 |
1998-04-15 |
Creative Biomolecules, Inc. |
Chimeric multivalent protein analogues and methods of use thereof
|
|
ATE348175T1
(de)
|
1992-07-17 |
2007-01-15 |
Dana Farber Cancer Inst Inc |
Method eder intrazellularen bindung von zielgerichteten molekülen
|
|
ATE203767T1
(de)
|
1992-08-21 |
2001-08-15 |
Univ Bruxelles |
Immunoglobuline ohne leichte ketten
|
|
EP0702721B1
(en)
|
1993-06-09 |
2001-01-03 |
Unilever N.V. |
Process for producing fusion proteins comprising scfv fragments by a transformed mould
|
|
US6091639A
(en)
|
1993-08-27 |
2000-07-18 |
Kabushiki Kaisha Toshiba |
Non-volatile semiconductor memory device and data programming method
|
|
JPH10501681A
(ja)
|
1994-02-22 |
1998-02-17 |
ダナ−ファーバー キャンサー インスティチュート |
核酸送達システムならびにその合成および使用方法
|
|
EP0739981A1
(en)
|
1995-04-25 |
1996-10-30 |
Vrije Universiteit Brussel |
Variable fragments of immunoglobulins - use for therapeutic or veterinary purposes
|
|
AU7298398A
(en)
|
1996-11-19 |
1998-06-10 |
Sangstat Medical Corporation |
Enhanced effects for hapten conjugated therapeutics
|
|
US6342369B1
(en)
|
1997-05-15 |
2002-01-29 |
Genentech, Inc. |
Apo-2-receptor
|
|
EP1027439B1
(en)
|
1997-10-27 |
2010-03-17 |
Bac Ip B.V. |
Multivalent antigen-binding proteins
|
|
BR9907241A
(pt)
|
1998-01-26 |
2000-10-17 |
Unilever Nv |
Biblioteca de expressão, processo para preparar a mesma, uso de uma fonte não imunizada de sequências de ácido nucleico, e, processos para preparar fragmentos de anticorpos e, para preparar um anticorpo
|
|
EP1469883A2
(en)
|
1998-02-19 |
2004-10-27 |
Xcyte Therapies, Inc. |
Compositions and methods for regulating lymphocyte activation
|
|
GB9824632D0
(en)
|
1998-11-10 |
1999-01-06 |
Celltech Therapeutics Ltd |
Biological compounds
|
|
DE60013767T3
(de)
|
1999-01-19 |
2009-07-09 |
Unilever N.V. |
Verfahren zur herstellung von antikörperfragmenten
|
|
EP2180054A1
(en)
|
1999-12-24 |
2010-04-28 |
Genentech, Inc. |
Methods and compositions for prolonging elimination half-times of bioactive compounds
|
|
MXPA02010011A
(es)
|
2000-04-11 |
2003-04-25 |
Genentech Inc |
Anticuerpos multivalentes y usos para los mismos.
|
|
WO2001079444A2
(en)
|
2000-04-12 |
2001-10-25 |
Human Genome Sciences, Inc |
Albumin fusion proteins
|
|
US7279160B2
(en)
|
2000-05-02 |
2007-10-09 |
The Uab Research Foundation |
Combinations of DR5 antibodies and other therapeutic agents
|
|
TWI318983B
(en)
|
2000-05-02 |
2010-01-01 |
Uab Research Foundation |
An antibody selective for a tumor necrosis factor-related apoptosis-inducing ligand receptor and uses thereof
|
|
WO2002057445A1
(en)
|
2000-05-26 |
2002-07-25 |
National Research Council Of Canada |
Single-domain brain-targeting antibody fragments derived from llama antibodies
|
|
WO2001090190A2
(en)
|
2000-05-26 |
2001-11-29 |
National Research Council Of Canada |
Single-domain antigen-binding antibody fragments derived from llama antibodies
|
|
US6741957B1
(en)
|
2000-07-21 |
2004-05-25 |
Daimlerchrysler Corporation |
Analytical tire model for vehicle durability and ride comfort analysis
|
|
US7829084B2
(en)
|
2001-01-17 |
2010-11-09 |
Trubion Pharmaceuticals, Inc. |
Binding constructs and methods for use thereof
|
|
EP1377306A1
(en)
|
2001-03-09 |
2004-01-07 |
Dyax Corp. |
Serum albumin binding moieties
|
|
GB0110029D0
(en)
|
2001-04-24 |
2001-06-13 |
Grosveld Frank |
Transgenic animal
|
|
JP4303105B2
(ja)
|
2001-06-28 |
2009-07-29 |
ドマンティス リミテッド |
二重特異性リガンドとその利用
|
|
WO2004003019A2
(en)
|
2002-06-28 |
2004-01-08 |
Domantis Limited |
Immunoglobin single variant antigen-binding domains and dual-specific constructs
|
|
US20060073141A1
(en)
|
2001-06-28 |
2006-04-06 |
Domantis Limited |
Compositions and methods for treating inflammatory disorders
|
|
EP1425694A2
(en)
|
2001-08-03 |
2004-06-09 |
Medical Research Council |
Method of identifying a consensus sequence for intracellular antibodies
|
|
JP4213586B2
(ja)
|
2001-09-13 |
2009-01-21 |
株式会社抗体研究所 |
ラクダ抗体ライブラリーの作製方法
|
|
JP2005289809A
(ja)
|
2001-10-24 |
2005-10-20 |
Vlaams Interuniversitair Inst Voor Biotechnologie Vzw (Vib Vzw) |
突然変異重鎖抗体
|
|
ES2357225T3
(es)
|
2001-11-01 |
2011-04-20 |
Uab Research Foundation |
Combinaciones de anticuerpos anti-dr5 y anticuerpos anti-dr4 y otros agentes terapéuticos.
|
|
AU2002360307B2
(en)
|
2001-11-01 |
2008-01-17 |
The Uab Research Foundation |
Combinations of DR5 antibody and other therapeutic agents
|
|
KR100599789B1
(ko)
|
2001-12-03 |
2006-07-12 |
삼성에스디아이 주식회사 |
방열효율이 향상된 플라즈마 디스플레이 장치 및 그 제조방법
|
|
AU2002351896A1
(en)
|
2001-12-11 |
2003-06-23 |
Ablynx N.V. |
Method for displaying loops from immunoglobulin domains in different contexts
|
|
US20050037358A1
(en)
|
2001-12-21 |
2005-02-17 |
Serge Muyldermans |
Method for cloning of variable domain sequences
|
|
CA2471645A1
(en)
|
2002-01-03 |
2003-07-10 |
Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw |
Immunoconjugates useful for treatment of tumours
|
|
US7004940B2
(en)
|
2002-10-10 |
2006-02-28 |
Ethicon, Inc. |
Devices for performing thermal ablation having movable ultrasound transducers
|
|
EP2284192A3
(en)
|
2002-11-08 |
2011-07-20 |
Ablynx N.V. |
Camelidae antibodies for sublingual administration
|
|
BRPI0316092B8
(pt)
|
2002-11-08 |
2021-05-25 |
Ablynx Nv |
anticorpos de domínio único direcionados contra o fator de necrose tumoral alfa e usos para os mesmos
|
|
WO2004050895A2
(en)
|
2002-11-27 |
2004-06-17 |
Irm Llc |
Methods and compositions for inducing apoptosis in cancer cells
|
|
GB0228210D0
(en)
|
2002-12-03 |
2003-01-08 |
Babraham Inst |
Single chain antibodies
|
|
WO2004051268A1
(en)
|
2002-12-03 |
2004-06-17 |
Celltech R & D Limited |
Assay for identifying antibody producing cells
|
|
GB0230203D0
(en)
|
2002-12-27 |
2003-02-05 |
Domantis Ltd |
Fc fusion
|
|
ATE444984T1
(de)
|
2002-12-31 |
2009-10-15 |
Nektar Therapeutics Al Corp |
Hydrolysestabile maleimidendgruppen-enthaltende polymere
|
|
GB0312481D0
(en)
|
2003-05-30 |
2003-07-09 |
Celltech R&D Ltd |
Antibodies
|
|
ES2315664T3
(es)
|
2003-06-30 |
2009-04-01 |
Domantis Limited |
Anticuerpos de dominio unico (dab) pegilados.
|
|
WO2005018629A1
(en)
|
2003-08-12 |
2005-03-03 |
Yarbrough William M |
Treatment for acne vulgaris and method of use
|
|
ATE554390T1
(de)
|
2003-08-20 |
2012-05-15 |
Ucb Pharma Sa |
Verfahren zur gewinnung von antikörpern
|
|
GB0328261D0
(en)
*
|
2003-12-05 |
2004-01-07 |
Univ Groningen |
Improved cytokine design
|
|
KR20070010046A
(ko)
|
2004-04-06 |
2007-01-19 |
제넨테크, 인크. |
Dr5 항체 및 그의 용도
|
|
WO2005114187A2
(en)
|
2004-04-23 |
2005-12-01 |
The United States Of America As Represented By Thesecretary, Department Of Health And Human Services |
Methods and compositions for diagnosing aids and other diseases and conditions involving immune system activation
|
|
US7527973B2
(en)
|
2004-06-21 |
2009-05-05 |
Washington University |
Antibodies against West Nile Virus and therapeutic and prophylactic uses thereof
|
|
US20060008601A1
(en)
|
2004-06-25 |
2006-01-12 |
Zeik Douglas B |
Flexible laminate having an integrated pressure release valve
|
|
WO2006008548A2
(en)
|
2004-07-22 |
2006-01-26 |
Erasmus University Medical Centre Rotterdam |
Binding molecules
|
|
US7563443B2
(en)
|
2004-09-17 |
2009-07-21 |
Domantis Limited |
Monovalent anti-CD40L antibody polypeptides and compositions thereof
|
|
WO2006040153A2
(en)
|
2004-10-13 |
2006-04-20 |
Ablynx N.V. |
Single domain camelide anti -amyloid beta antibodies and polypeptides comprising the same for the treatment and diagnosis of degenarative neural diseases such as alzheimer's disease
|
|
WO2006040154A2
(en)
|
2004-10-14 |
2006-04-20 |
Dublin City University |
Prokaryotic two hybrid system
|
|
JO3000B1
(ar)
|
2004-10-20 |
2016-09-05 |
Genentech Inc |
مركبات أجسام مضادة .
|
|
AU2005325801A1
(en)
|
2005-01-31 |
2006-08-03 |
Ablynx N.V. |
Method for generating variable domain sequences of heavy chain antibodies
|
|
GB2424983A
(en)
|
2005-04-07 |
2006-10-11 |
Autoliv Dev |
Seatbelt pretensioner control system
|
|
EP3613767A1
(en)
|
2005-05-18 |
2020-02-26 |
Ablynx N.V. |
Improved nanobodiestm against tumor cecrosis factor-alpha
|
|
EP3415535B1
(en)
|
2005-05-20 |
2020-12-09 |
Ablynx N.V. |
Improved nanobodies tm for the treatment of aggregation-mediated disorders
|
|
WO2007112940A2
(en)
|
2006-03-31 |
2007-10-11 |
Ablynx N.V. |
Albumin-derived amino acid sequence, use thereof for increasing the half-life of therapeutic proteins and of other therapeutic compounds and entities, and constructs comprising the same
|
|
CA2649009A1
(en)
|
2006-04-14 |
2007-10-25 |
Ablynx N.V. |
Dp-78-like nanobodies
|
|
EP2057191A1
(en)
|
2006-08-18 |
2009-05-13 |
Ablynx N.V. |
Amino acid sequences directed against il-6r and polypeptides comprising the same for the treatment of deseases and disorders associated with il-6-mediated signalling
|
|
CA2663042A1
(en)
|
2006-09-08 |
2008-03-13 |
Ablynx N.V. |
Serum albumin binding proteins with long half-lives
|
|
WO2008043821A1
(en)
|
2006-10-11 |
2008-04-17 |
Ablynx N. V. |
Amino acid sequences that bind to serum proteins in a manner that is essentially independent of the ph, compounds comprising the same, and use thereof
|
|
WO2008066854A2
(en)
|
2006-11-28 |
2008-06-05 |
Novartis Ag |
Methods and compositions for inducing apoptosis in cancer cells
|
|
US20080267949A1
(en)
|
2006-12-05 |
2008-10-30 |
Ablynx N.V. |
Peptides capable of binding to serum proteins
|
|
JP5302519B2
(ja)
|
2007-08-03 |
2013-10-02 |
倉敷紡績株式会社 |
ヒトパピローマウイルスを検出するためのプライマーセット及びプローブ
|
|
AU2007358569B2
(en)
|
2007-09-07 |
2014-09-04 |
Ablynx N.V. |
Binding molecules with multiple binding sites, compositions comprising the same and uses thereof
|
|
WO2009127691A1
(en)
|
2008-04-17 |
2009-10-22 |
Ablynx N.V. |
Peptides capable of binding to serum proteins and compounds, constructs and polypeptides comprising the same
|