JP2012525829A5 - - Google Patents
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- Publication number
- JP2012525829A5 JP2012525829A5 JP2012509035A JP2012509035A JP2012525829A5 JP 2012525829 A5 JP2012525829 A5 JP 2012525829A5 JP 2012509035 A JP2012509035 A JP 2012509035A JP 2012509035 A JP2012509035 A JP 2012509035A JP 2012525829 A5 JP2012525829 A5 JP 2012525829A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- antigen
- seq
- isolated antibody
- nos
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17586009P | 2009-05-06 | 2009-05-06 | |
| US61/175,860 | 2009-05-06 | ||
| PCT/EP2010/056129 WO2010136311A2 (en) | 2009-05-06 | 2010-05-05 | Compositions and methods for antibodies targeting complement protein c3b |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012525829A JP2012525829A (ja) | 2012-10-25 |
| JP2012525829A5 true JP2012525829A5 (enExample) | 2013-06-20 |
Family
ID=43063291
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012509035A Pending JP2012525829A (ja) | 2009-05-06 | 2010-05-05 | 補体タンパク質Ｃ３ｂを標的とする抗体の組成物および方法 |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US20100291106A1 (enExample) |
| EP (1) | EP2427491A2 (enExample) |
| JP (1) | JP2012525829A (enExample) |
| KR (1) | KR20120088551A (enExample) |
| CN (1) | CN102459334A (enExample) |
| AR (1) | AR076655A1 (enExample) |
| AU (1) | AU2010252156A1 (enExample) |
| CA (1) | CA2760757A1 (enExample) |
| CL (1) | CL2011002756A1 (enExample) |
| CO (1) | CO6440515A2 (enExample) |
| EA (1) | EA201101593A1 (enExample) |
| EC (1) | ECSP11011445A (enExample) |
| IL (1) | IL216061A0 (enExample) |
| MA (1) | MA33402B1 (enExample) |
| MX (1) | MX2011011754A (enExample) |
| PE (1) | PE20120899A1 (enExample) |
| SG (1) | SG175432A1 (enExample) |
| TN (1) | TN2011000528A1 (enExample) |
| TW (1) | TW201043638A (enExample) |
| UY (1) | UY32612A (enExample) |
| WO (1) | WO2010136311A2 (enExample) |
| ZA (1) | ZA201107551B (enExample) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8512738B2 (en) | 2004-04-30 | 2013-08-20 | Allergan, Inc. | Biodegradable intravitreal tyrosine kinase implants |
| PT2044111E (pt) | 2006-06-21 | 2014-11-12 | Univ Colorado Regents | Abordagem seletiva do fator h do complemento para o tratamento de doenças |
| RS20120461A1 (sr) | 2009-07-02 | 2013-06-28 | Musc Foundation For Research Development | Metode za stimulaciju regeneracije jetre |
| EP2496259B1 (en) | 2009-11-05 | 2017-02-22 | Alexion Pharmaceuticals, Inc. | Treatment of paroxysmal nocturnal hemoglobinuria |
| JP5986990B2 (ja) | 2010-05-14 | 2016-09-06 | ザ リージェンツ オブ ザ ユニヴァーシティ オブ コロラド，ア ボディ コーポレート | 改善された補体レセプター２（ｃｒ２）ターゲティング基 |
| MX2012014975A (es) | 2010-06-22 | 2013-03-12 | Univ Colorado Regents | Anticuerpos al fragmento c3d de componente 3 de complemento. |
| WO2012075023A2 (en) * | 2010-11-29 | 2012-06-07 | Novelmed Therapeutics, Inc. | Neoantibodies for diagnosing tissue injury |
| CN104220453B (zh) * | 2012-04-03 | 2018-03-09 | 诺沃姆德治疗公司 | 人源化的嵌合抗因子c3抗体及其用途 |
| US10413620B2 (en) | 2012-08-17 | 2019-09-17 | The Regents Of The University Of Colorado, A Body Corporate | Light-emitting versions of the monoclonal antibody to C3D (MAB 3D29) for imaging |
| JP2015535212A (ja) | 2012-08-17 | 2015-12-10 | ザ・リージエンツ・オブ・ザ・ユニバーシテイ・オブ・コロラド、ア・ボデイー・コーポレイト | 補体活性化を検出するための組成物および方法 |
| WO2014066744A2 (en) | 2012-10-25 | 2014-05-01 | True North Therapeutics, Inc. | Anti-complement c1s antibodies and uses thereof |
| PL2914291T3 (pl) | 2012-11-02 | 2022-10-03 | Bioverativ Usa Inc. | Przeciwciała anty-C1s dopełniacza i ich zastosowania |
| US9657111B2 (en) | 2012-11-29 | 2017-05-23 | Bayer Healthcare Llc | Humanized monoclonal antibodies against activated protein C and uses thereof |
| EP3473272A1 (en) | 2013-03-29 | 2019-04-24 | Alexion Pharmaceuticals, Inc. | Compositions and methods for increasing the serum half-life of a therapeutic agent targeting complement c5 |
| SI3011345T1 (sl) | 2013-08-07 | 2017-12-29 | Alexion Pharmaceuticals, Inc. | Biomarkerski proteini za atipični hemolitični uremični sindrom (ahus) |
| CA2926812A1 (en) * | 2013-10-07 | 2015-04-16 | Massachusetts Eye And Ear Infirmary | Methods of preventing or reducing photoreceptor cell death |
| WO2015099838A2 (en) | 2013-12-24 | 2015-07-02 | Novelmed Therapeutics, Inc. | Compositions and methods of treating ocular diseases |
| KR20160126054A (ko) | 2014-02-27 | 2016-11-01 | 알러간, 인코포레이티드 | 보체 인자 Bb 항체 |
| US11077187B2 (en) | 2015-11-17 | 2021-08-03 | Oklahoma Medical Research Foundation | Epitope of optimized humanized monoclonal antibodies against activated protein C and uses thereof |
| EP4652926A3 (en) | 2016-10-12 | 2026-03-18 | Bioverativ USA Inc. | Anti-c1s antibodies and methods of use thereof |
| EP3526248A4 (en) | 2016-10-17 | 2020-07-08 | Musc Foundation for Research Development | COMPOSITIONS AND METHODS FOR TREATING CENTRAL NERVOUS SYSTEM DAMAGE |
| KR20200138290A (ko) | 2018-04-03 | 2020-12-09 | 엔지엠 바이오파마슈티컬스, 아이엔씨. | C3-결합제 및 이의 사용 방법 |
| EP4257602A3 (en) | 2018-06-11 | 2023-12-27 | Aarhus Universitet | Single domain antibodies for complement regulation |
| GB2583560A (en) | 2018-12-11 | 2020-11-04 | Admirx Inc | Fusion protein constructs for complement associated disease |
| EP4308609A4 (en) * | 2021-03-19 | 2025-06-04 | Elpis Biopharmaceuticals | Antibodies specific to sialic acid-binding ig-like lectin 15 and uses thereof |
| WO2024108529A1 (en) * | 2022-11-25 | 2024-05-30 | Linno Pharmaceuticals Inc. | Properdin binding protein and use thereof |
| PE20250390A1 (es) | 2021-12-22 | 2025-02-11 | Boehringer Ingelheim Int | Anticuerpos anti-c3 y fragmentos de union al antigeno de estos y sus usos para tratar enfermedades oftalmicas u oculares |
| KR20230105972A (ko) * | 2022-01-05 | 2023-07-12 | 주식회사 카나프테라퓨틱스 | 혈관신생 억제제가 결합된 항-C3b 항체 또는 항-C5 항체 및 이의 용도 |
| CN114874329A (zh) * | 2022-05-19 | 2022-08-09 | 江苏大学 | 一种补体活化C1s酶荧光检测试剂盒及检测方法与应用 |
| US20240228652A9 (en) * | 2022-09-20 | 2024-07-11 | Visterra, Inc. | Treatment of complement mediated diseases and disorders with c3b antibodies |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE452065B (sv) * | 1986-04-11 | 1987-11-09 | Ulf R Nilsson | Antikroppspreparation vars antikroppar er specifika for determinanter i c3 b regionen hos denaturerat humant c3 samt dess anvendning och framstellning |
| US5859205A (en) * | 1989-12-21 | 1999-01-12 | Celltech Limited | Humanised antibodies |
| DK2026073T3 (en) * | 2000-04-29 | 2016-07-25 | Univ Iowa Res Found | Diagnosis and treatment of macular degeneration-related disorders |
| US7838165B2 (en) * | 2004-07-02 | 2010-11-23 | Kabushiki Kaisha Toshiba | Carbon fiber synthesizing catalyst and method of making thereof |
| WO2006012621A2 (en) * | 2004-07-23 | 2006-02-02 | University Of Virginia Patent Foundation | Compositions and methods for regulating the alternative pathway of complement |
| CA2588892A1 (en) * | 2004-12-02 | 2006-06-08 | Dormantis Limited | Anti-il-1r1 single domain antibodies and therapeutic uses |
| PL2860192T3 (pl) * | 2005-10-12 | 2018-03-30 | Morphosys Ag | Wytwarzanie i profilowanie w pełni ludzkich, uzyskanych z HuCAL GOLD terapeutycznych przeciwciał swoistych wobec ludzkiego CD38 |
| GB0613209D0 (en) * | 2006-07-03 | 2006-08-09 | Ucb Sa | Methods |
| US8192742B2 (en) * | 2007-03-23 | 2012-06-05 | NovelMed Therapeutics | Method of inhibiting complement activation with human anti-factor C3 antibodies and use thereof |
| KR101572700B1 (ko) * | 2007-06-07 | 2015-11-30 | 제넨테크, 인크. | 보체-관련 장애의 예방 및 치료를 위한 Ｃ３ｂ 항체 및 방법 |
| AR069130A1 (es) * | 2007-11-02 | 2009-12-30 | Novartis Ag | Moleculas de enlace de la opsonina principal del complemento (c3b) y metodos para modular el componente de complemento |
-
2010
- 2010-05-04 US US12/773,246 patent/US20100291106A1/en not_active Abandoned
- 2010-05-05 EA EA201101593A patent/EA201101593A1/ru unknown
- 2010-05-05 JP JP2012509035A patent/JP2012525829A/ja active Pending
- 2010-05-05 AU AU2010252156A patent/AU2010252156A1/en not_active Abandoned
- 2010-05-05 TW TW099114417A patent/TW201043638A/zh unknown
- 2010-05-05 KR KR1020117029046A patent/KR20120088551A/ko not_active Withdrawn
- 2010-05-05 EP EP10747599A patent/EP2427491A2/en not_active Withdrawn
- 2010-05-05 AR ARP100101527A patent/AR076655A1/es not_active Application Discontinuation
- 2010-05-05 SG SG2011080330A patent/SG175432A1/en unknown
- 2010-05-05 CN CN201080026538XA patent/CN102459334A/zh active Pending
- 2010-05-05 MX MX2011011754A patent/MX2011011754A/es not_active Application Discontinuation
- 2010-05-05 PE PE2011001908A patent/PE20120899A1/es not_active Application Discontinuation
- 2010-05-05 MA MA34415A patent/MA33402B1/fr unknown
- 2010-05-05 CA CA2760757A patent/CA2760757A1/en not_active Abandoned
- 2010-05-05 WO PCT/EP2010/056129 patent/WO2010136311A2/en not_active Ceased
- 2010-05-06 UY UY0001032612A patent/UY32612A/es not_active Application Discontinuation
-
2011
- 2011-10-14 ZA ZA2011/07551A patent/ZA201107551B/en unknown
- 2011-10-19 TN TNP2011000528A patent/TN2011000528A1/en unknown
- 2011-10-31 IL IL216061A patent/IL216061A0/en unknown
- 2011-11-04 CL CL2011002756A patent/CL2011002756A1/es unknown
- 2011-11-04 CO CO11150255A patent/CO6440515A2/es not_active Application Discontinuation
- 2011-11-08 EC EC2011011445A patent/ECSP11011445A/es unknown
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