|
US3773919A
(en)
|
1969-10-23 |
1973-11-20 |
Du Pont |
Polylactide-drug mixtures
|
|
US4179337A
(en)
|
1973-07-20 |
1979-12-18 |
Davis Frank F |
Non-immunogenic polypeptides
|
|
US4263428A
(en)
|
1978-03-24 |
1981-04-21 |
The Regents Of The University Of California |
Bis-anthracycline nucleic acid function inhibitors and improved method for administering the same
|
|
JPS6023084B2
(ja)
|
1979-07-11 |
1985-06-05 |
味の素株式会社 |
代用血液
|
|
US4399216A
(en)
|
1980-02-25 |
1983-08-16 |
The Trustees Of Columbia University |
Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
|
|
US4376110A
(en)
|
1980-08-04 |
1983-03-08 |
Hybritech, Incorporated |
Immunometric assays using monoclonal antibodies
|
|
IE52535B1
(en)
|
1981-02-16 |
1987-12-09 |
Ici Plc |
Continuous release pharmaceutical compositions
|
|
US4640835A
(en)
|
1981-10-30 |
1987-02-03 |
Nippon Chemiphar Company, Ltd. |
Plasminogen activator derivatives
|
|
DE3374837D1
(en)
|
1982-02-17 |
1988-01-21 |
Ciba Geigy Ag |
Lipids in the aqueous phase
|
|
US4816567A
(en)
|
1983-04-08 |
1989-03-28 |
Genentech, Inc. |
Recombinant immunoglobin preparations
|
|
HUT35524A
(en)
|
1983-08-02 |
1985-07-29 |
Hoechst Ag |
Process for preparing pharmaceutical compositions containing regulatory /regulative/ peptides providing for the retarded release of the active substance
|
|
DE3474511D1
(en)
|
1983-11-01 |
1988-11-17 |
Terumo Corp |
Pharmaceutical composition containing urokinase
|
|
US4496689A
(en)
|
1983-12-27 |
1985-01-29 |
Miles Laboratories, Inc. |
Covalently attached complex of alpha-1-proteinase inhibitor with a water soluble polymer
|
|
US4740461A
(en)
|
1983-12-27 |
1988-04-26 |
Genetics Institute, Inc. |
Vectors and methods for transformation of eucaryotic cells
|
|
EP0154316B1
(en)
|
1984-03-06 |
1989-09-13 |
Takeda Chemical Industries, Ltd. |
Chemically modified lymphokine and production thereof
|
|
US4945050A
(en)
|
1984-11-13 |
1990-07-31 |
Cornell Research Foundation, Inc. |
Method for transporting substances into living cells and tissues and apparatus therefor
|
|
US4751180A
(en)
|
1985-03-28 |
1988-06-14 |
Chiron Corporation |
Expression using fused genes providing for protein product
|
|
EP0206448B1
(en)
|
1985-06-19 |
1990-11-14 |
Ajinomoto Co., Inc. |
Hemoglobin combined with a poly(alkylene oxide)
|
|
US4935233A
(en)
|
1985-12-02 |
1990-06-19 |
G. D. Searle And Company |
Covalently linked polypeptide cell modulators
|
|
EP0272253A4
(en)
|
1986-03-07 |
1990-02-05 |
Massachusetts Inst Technology |
METHOD FOR IMPROVING GLYCOPROTE INSTABILITY.
|
|
CA1310924C
(en)
|
1986-04-24 |
1992-12-01 |
Francis P. Mccormick |
Infective drug delivery system
|
|
US4791192A
(en)
|
1986-06-26 |
1988-12-13 |
Takeda Chemical Industries, Ltd. |
Chemically modified protein with polyethyleneglycol
|
|
US4959455A
(en)
|
1986-07-14 |
1990-09-25 |
Genetics Institute, Inc. |
Primate hematopoietic growth factors IL-3 and pharmaceutical compositions
|
|
US4946778A
(en)
|
1987-09-21 |
1990-08-07 |
Genex Corporation |
Single polypeptide chain binding molecules
|
|
US4912040A
(en)
|
1986-11-14 |
1990-03-27 |
Genetics Institute, Inc. |
Eucaryotic expression system
|
|
US5011912A
(en)
|
1986-12-19 |
1991-04-30 |
Immunex Corporation |
Hybridoma and monoclonal antibody for use in an immunoaffinity purification system
|
|
US4970154A
(en)
|
1987-10-09 |
1990-11-13 |
Baylor College Of Medicine |
Method for inserting foreign genes into cells using pulsed radiofrequency
|
|
US4965195A
(en)
|
1987-10-26 |
1990-10-23 |
Immunex Corp. |
Interleukin-7
|
|
DE3889853D1
(de)
|
1987-11-05 |
1994-07-07 |
Hybritech Inc |
Polysaccharidmodifizierte Immunglobuline mit reduziertem immunogenem Potential oder verbesserter Pharmakokinetik.
|
|
US5158881A
(en)
|
1987-11-17 |
1992-10-27 |
Brown University Research Foundation |
Method and system for encapsulating cells in a tubular extrudate in separate cell compartments
|
|
US4892538A
(en)
|
1987-11-17 |
1990-01-09 |
Brown University Research Foundation |
In vivo delivery of neurotransmitters by implanted, encapsulated cells
|
|
US5106627A
(en)
|
1987-11-17 |
1992-04-21 |
Brown University Research Foundation |
Neurological therapy devices
|
|
US4968607A
(en)
|
1987-11-25 |
1990-11-06 |
Immunex Corporation |
Interleukin-1 receptors
|
|
US5011472A
(en)
|
1988-09-06 |
1991-04-30 |
Brown University Research Foundation |
Implantable delivery system for biological factors
|
|
GB8823869D0
(en)
|
1988-10-12 |
1988-11-16 |
Medical Res Council |
Production of antibodies
|
|
AU643427B2
(en)
|
1988-10-31 |
1993-11-18 |
Immunex Corporation |
Interleukin-4 receptors
|
|
JP2989002B2
(ja)
|
1988-12-22 |
1999-12-13 |
キリン―アムジエン・インコーポレーテツド |
化学修飾顆粒球コロニー刺激因子
|
|
US5530101A
(en)
|
1988-12-28 |
1996-06-25 |
Protein Design Labs, Inc. |
Humanized immunoglobulins
|
|
US5288855A
(en)
|
1989-01-23 |
1994-02-22 |
Farmitalia Carlo Erba |
Extracellular form of the human fibroblast growth factor receptor
|
|
HU215581B
(hu)
|
1989-07-06 |
1999-01-28 |
Regents Of The University Of California |
Eljárás fibroblaszt növekedési faktor receptorok előállítására és terápiás alkalmazására
|
|
US5683888A
(en)
|
1989-07-22 |
1997-11-04 |
University Of Wales College Of Medicine |
Modified bioluminescent proteins and their use
|
|
US5676954A
(en)
|
1989-11-03 |
1997-10-14 |
Vanderbilt University |
Method of in vivo delivery of functioning foreign genes
|
|
HK1000547A1
(en)
|
1989-12-22 |
1998-04-03 |
Merck Serono Sa |
Endogenous gene expression modification with regulatory element by way of homologous recombination
|
|
US5272071A
(en)
|
1989-12-22 |
1993-12-21 |
Applied Research Systems Ars Holding N.V. |
Method for the modification of the expression characteristics of an endogenous gene of a given cell line
|
|
US5292658A
(en)
|
1989-12-29 |
1994-03-08 |
University Of Georgia Research Foundation, Inc. Boyd Graduate Studies Research Center |
Cloning and expressions of Renilla luciferase
|
|
WO1991010470A1
(en)
|
1990-01-08 |
1991-07-25 |
Brown University Research Foundation |
Devices and methods for enhanced delivery of active factors
|
|
US6673986B1
(en)
|
1990-01-12 |
2004-01-06 |
Abgenix, Inc. |
Generation of xenogeneic antibodies
|
|
US6713610B1
(en)
|
1990-01-12 |
2004-03-30 |
Raju Kucherlapati |
Human antibodies derived from immunized xenomice
|
|
ES2087997T3
(es)
|
1990-01-12 |
1996-08-01 |
Cell Genesys Inc |
Generacion de anticuerpos xenogenicos.
|
|
US5672510A
(en)
|
1990-01-19 |
1997-09-30 |
Genetic Therapy, Inc. |
Retroviral vectors
|
|
AU651596B2
(en)
|
1990-06-05 |
1994-07-28 |
Immunex Corporation |
Type II interleukin-1 receptors
|
|
GB9014932D0
(en)
|
1990-07-05 |
1990-08-22 |
Celltech Ltd |
Recombinant dna product and method
|
|
US6255458B1
(en)
|
1990-08-29 |
2001-07-03 |
Genpharm International |
High affinity human antibodies and human antibodies against digoxin
|
|
US5625126A
(en)
|
1990-08-29 |
1997-04-29 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5814318A
(en)
|
1990-08-29 |
1998-09-29 |
Genpharm International Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5545806A
(en)
|
1990-08-29 |
1996-08-13 |
Genpharm International, Inc. |
Ransgenic non-human animals for producing heterologous antibodies
|
|
US5770429A
(en)
|
1990-08-29 |
1998-06-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US6300129B1
(en)
|
1990-08-29 |
2001-10-09 |
Genpharm International |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5874299A
(en)
|
1990-08-29 |
1999-02-23 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5789650A
(en)
|
1990-08-29 |
1998-08-04 |
Genpharm International, Inc. |
Transgenic non-human animals for producing heterologous antibodies
|
|
US5877397A
(en)
|
1990-08-29 |
1999-03-02 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
|
ES2108048T3
(es)
|
1990-08-29 |
1997-12-16 |
Genpharm Int |
Produccion y utilizacion de animales inferiores transgenicos capaces de producir anticuerpos heterologos.
|
|
US5633425A
(en)
|
1990-08-29 |
1997-05-27 |
Genpharm International, Inc. |
Transgenic non-human animals capable of producing heterologous antibodies
|
|
US5661016A
(en)
|
1990-08-29 |
1997-08-26 |
Genpharm International Inc. |
Transgenic non-human animals capable of producing heterologous antibodies of various isotypes
|
|
US5217889A
(en)
|
1990-10-19 |
1993-06-08 |
Roninson Igor B |
Methods and applications for efficient genetic suppressor elements
|
|
US5252714A
(en)
|
1990-11-28 |
1993-10-12 |
The University Of Alabama In Huntsville |
Preparation and use of polyethylene glycol propionaldehyde
|
|
US5229501A
(en)
|
1991-01-11 |
1993-07-20 |
Chiron Corporation |
Expression and use of human fibroblast growth factor receptor
|
|
JP3126980B2
(ja)
|
1991-03-11 |
2001-01-22 |
ザ・ユニバーシテイ・オブ・ジヨージア・リサーチ・フアウンデーシヨン・インコーポレーテツド |
レニラ（ｒｅｎｉｌｌａ）ルシフェラーゼのクローニング及び発現
|
|
US6565841B1
(en)
|
1991-03-15 |
2003-05-20 |
Amgen, Inc. |
Pulmonary administration of granulocyte colony stimulating factor
|
|
CA2111348A1
(en)
|
1991-06-14 |
1992-12-23 |
John S. Logan |
Production of human hemoglobin in transgenic pigs
|
|
WO1994004679A1
(en)
|
1991-06-14 |
1994-03-03 |
Genentech, Inc. |
Method for making humanized antibodies
|
|
JPH06508880A
(ja)
|
1991-07-08 |
1994-10-06 |
ユニバーシティ オブ マサチューセッツ アット アムハースト |
サーモトロピック液晶セグメント化ブロックコポリマー
|
|
US5262522A
(en)
|
1991-11-22 |
1993-11-16 |
Immunex Corporation |
Receptor for oncostatin M and leukemia inhibitory factor
|
|
IL100219A0
(en)
|
1991-12-02 |
1992-09-06 |
Yeda Res & Dev |
Variable region within fibroblast growth factor receptors that confers ligand specificity
|
|
JPH05244982A
(ja)
|
1991-12-06 |
1993-09-24 |
Sumitomo Chem Co Ltd |
擬人化ｂ−ｂ１０
|
|
US5470582A
(en)
|
1992-02-07 |
1995-11-28 |
Syntex (U.S.A.) Inc. |
Controlled delivery of pharmaceuticals from preformed porous polymeric microparticles
|
|
US5234784A
(en)
|
1992-04-01 |
1993-08-10 |
Eastman Kodak Company |
Method of making a projection viewable transparency comprising an electrostatographic toner image
|
|
US5364791A
(en)
|
1992-05-14 |
1994-11-15 |
Elisabetta Vegeto |
Progesterone receptor having C. terminal hormone binding domain truncations
|
|
EP0646182B1
(en)
|
1992-06-18 |
1996-08-28 |
The Whittier Institute For Diabetes And Endocrinology |
Process for detection of neoplastic disease
|
|
JPH07509137A
(ja)
|
1992-07-24 |
1995-10-12 |
セル ジェネシス，インク． |
異種抗体の生産
|
|
WO1994010308A1
(en)
|
1992-10-23 |
1994-05-11 |
Immunex Corporation |
Methods of preparing soluble, oligomeric proteins
|
|
US5489743A
(en)
|
1993-01-19 |
1996-02-06 |
Amgen Inc. |
Transgenic animal models for thrombocytopenia
|
|
US5581476A
(en)
|
1993-01-28 |
1996-12-03 |
Amgen Inc. |
Computer-based methods and articles of manufacture for preparing G-CSF analogs
|
|
JPH08509870A
(ja)
|
1993-05-26 |
1996-10-22 |
オンタリオ キャンサー インスティテュート |
特定のｃｄ４５イソ型タンパク質の発現を遮断するトランスジェニック哺乳動物
|
|
US6664107B1
(en)
|
1993-05-26 |
2003-12-16 |
Ontario Cancer Institute, University Health Network |
CD45 disrupted nucleic acid
|
|
US5589362A
(en)
|
1993-06-14 |
1996-12-31 |
Basf Aktiengesellschaft |
Tetracycline regulated transcriptional modulators with altered DNA binding specificities
|
|
US5654168A
(en)
|
1994-07-01 |
1997-08-05 |
Basf Aktiengesellschaft |
Tetracycline-inducible transcriptional activator and tetracycline-regulated transcription units
|
|
EP0705334A1
(en)
|
1993-06-14 |
1996-04-10 |
Basf Aktiengesellschaft |
Tight control of gene expression in eucaryotic cells by tetracycline-responsive promoters
|
|
US5457035A
(en)
|
1993-07-23 |
1995-10-10 |
Immunex Corporation |
Cytokine which is a ligand for OX40
|
|
JP4098355B2
(ja)
|
1993-08-12 |
2008-06-11 |
ニューロテック ユーエスエー， インコーポレイテッド |
遺伝的に改変された細胞を含む生体適合性免疫隔離カプセル
|
|
AU694745B2
(en)
|
1993-09-10 |
1998-07-30 |
Trustees Of Columbia University In The City Of New York, The |
Uses of green fluorescent protein
|
|
WO1995021191A1
(en)
|
1994-02-04 |
1995-08-10 |
William Ward |
Bioluminescent indicator based upon the expression of a gene for a modified green-fluorescent protein
|
|
US5658785A
(en)
|
1994-06-06 |
1997-08-19 |
Children's Hospital, Inc. |
Adeno-associated virus materials and methods
|
|
US5484720A
(en)
|
1994-09-08 |
1996-01-16 |
Genentech, Inc. |
Methods for calcium phosphate transfection
|
|
US5824784A
(en)
|
1994-10-12 |
1998-10-20 |
Amgen Inc. |
N-terminally chemically modified protein compositions and methods
|
|
US5777079A
(en)
|
1994-11-10 |
1998-07-07 |
The Regents Of The University Of California |
Modified green fluorescent proteins
|
|
US6096871A
(en)
|
1995-04-14 |
2000-08-01 |
Genentech, Inc. |
Polypeptides altered to contain an epitope from the Fc region of an IgG molecule for increased half-life
|
|
EP0822830B1
(en)
|
1995-04-27 |
2008-04-02 |
Amgen Fremont Inc. |
Human anti-IL-8 antibodies, derived from immunized xenomice
|
|
CN1191568A
(zh)
|
1995-05-26 |
1998-08-26 |
曾尼卡有限公司 |
包含蜕皮激素受体的基因开关
|
|
AU705035B2
(en)
|
1995-06-07 |
1999-05-13 |
Baylor College Of Medicine |
Nucleic acid transporters for delivery of nucleic acids into a cell
|
|
CA2219080A1
(en)
|
1995-06-07 |
1996-12-27 |
Ariad Gene Therapeutics, Inc. |
Rapamycin-based regulation of biological events
|
|
US5874304A
(en)
|
1996-01-18 |
1999-02-23 |
University Of Florida Research Foundation, Inc. |
Humanized green fluorescent protein genes and methods
|
|
US5804387A
(en)
|
1996-02-01 |
1998-09-08 |
The Board Of Trustees Of The Leland Stanford Junior University |
FACS-optimized mutants of the green fluorescent protein (GFP)
|
|
US5876995A
(en)
|
1996-02-06 |
1999-03-02 |
Bryan; Bruce |
Bioluminescent novelty items
|
|
CA2244363C
(en)
|
1996-02-28 |
2006-11-14 |
Ariad Gene Therapeutics, Inc. |
Synthetic derivatives of rapamycin as multimerizing agents for chimeric proteins with immunophilin-derived domains
|
|
AU728657B2
(en)
|
1996-03-18 |
2001-01-18 |
Board Of Regents, The University Of Texas System |
Immunoglobulin-like domains with increased half-lives
|
|
US5679559A
(en)
|
1996-07-03 |
1997-10-21 |
University Of Utah Research Foundation |
Cationic polymer and lipoprotein-containing system for gene delivery
|
|
US5925558A
(en)
|
1996-07-16 |
1999-07-20 |
The Regents Of The University Of California |
Assays for protein kinases using fluorescent protein substrates
|
|
US5976796A
(en)
|
1996-10-04 |
1999-11-02 |
Loma Linda University |
Construction and expression of renilla luciferase and green fluorescent protein fusion genes
|
|
US6214795B1
(en)
|
1996-11-12 |
2001-04-10 |
Praecis Pharmaceuticals, Inc. |
Peptide compounds useful for modulating FGF receptor activity
|
|
EP2305027B1
(en)
|
1996-12-03 |
2014-07-02 |
Amgen Fremont Inc. |
Transgenic mammals having human Ig loci including plural VH and Vkappa regions and antibodies produced therefrom
|
|
US6458547B1
(en)
|
1996-12-12 |
2002-10-01 |
Prolume, Ltd. |
Apparatus and method for detecting and identifying infectious agents
|
|
AU739057B2
(en)
|
1996-12-26 |
2001-10-04 |
Shirankai Kyoto University Faculty Of Medicine Alumni Association Inc. |
Novel polypeptide, novel DNA, and novel antibody
|
|
CA2196496A1
(en)
|
1997-01-31 |
1998-07-31 |
Stephen William Watson Michnick |
Protein fragment complementation assay for the detection of protein-protein interactions
|
|
US6133426A
(en)
|
1997-02-21 |
2000-10-17 |
Genentech, Inc. |
Humanized anti-IL-8 monoclonal antibodies
|
|
US6235883B1
(en)
*
|
1997-05-05 |
2001-05-22 |
Abgenix, Inc. |
Human monoclonal antibodies to epidermal growth factor receptor
|
|
US6342220B1
(en)
|
1997-08-25 |
2002-01-29 |
Genentech, Inc. |
Agonist antibodies
|
|
GB9722131D0
(en)
|
1997-10-20 |
1997-12-17 |
Medical Res Council |
Method
|
|
US6150098A
(en)
|
1998-02-20 |
2000-11-21 |
Amgen Inc. |
Methods for identifying novel secreted mammalian polypeptides
|
|
EP1064360B1
(en)
|
1998-03-27 |
2008-03-05 |
Prolume, Ltd. |
Luciferases, gfp fluorescent proteins, their nucleic acids and the use thereof in diagnostics
|
|
US20020142374A1
(en)
|
1998-08-17 |
2002-10-03 |
Michael Gallo |
Generation of modified molecules with increased serum half-lives
|
|
US6548634B1
(en)
|
1998-09-30 |
2003-04-15 |
Chiron Corporation |
Synthetic peptides having FGF receptor affinity
|
|
US6660843B1
(en)
|
1998-10-23 |
2003-12-09 |
Amgen Inc. |
Modified peptides as therapeutic agents
|
|
EP1183051A2
(en)
|
1999-03-15 |
2002-03-06 |
Chiron Corporation |
Use of recombinant gene delivery vectors for treating or preventing diseases of the eye
|
|
US6833268B1
(en)
|
1999-06-10 |
2004-12-21 |
Abgenix, Inc. |
Transgenic animals for producing specific isotypes of human antibodies via non-cognate switch regions
|
|
CA2311201A1
(en)
|
1999-08-05 |
2001-02-05 |
Genset S.A. |
Ests and encoded human proteins
|
|
US7408047B1
(en)
|
1999-09-07 |
2008-08-05 |
Amgen Inc. |
Fibroblast growth factor-like polypeptides
|
|
US7459540B1
(en)
|
1999-09-07 |
2008-12-02 |
Amgen Inc. |
Fibroblast growth factor-like polypeptides
|
|
AU7368100A
(en)
|
1999-09-10 |
2001-04-10 |
Curagen Corporation |
Fibroblast growth factor polypeptide and nucleic acids encoding same
|
|
WO2001032678A1
(en)
|
1999-11-05 |
2001-05-10 |
Smithkline Beecham Corporation |
sbgFGF-19a
|
|
EP2163626A1
(en)
|
1999-11-18 |
2010-03-17 |
Novartis Vaccines and Diagnostics, Inc. |
Human FGF-21 gene and gene expression products
|
|
US6716626B1
(en)
|
1999-11-18 |
2004-04-06 |
Chiron Corporation |
Human FGF-21 nucleic acids
|
|
AU1628101A
(en)
|
1999-11-22 |
2001-06-04 |
Millennium Pharmaceuticals, Inc. |
Jaffa, a novel fibroblast growth factor family member and uses therefor
|
|
GB9928787D0
(en)
|
1999-12-03 |
2000-02-02 |
Medical Res Council |
Direct screening method
|
|
US7108984B2
(en)
|
2000-01-12 |
2006-09-19 |
Mount Sinai School Of Medicine |
Methods of identifying modulators of the FGF receptor
|
|
US20020081663A1
(en)
|
2000-01-05 |
2002-06-27 |
Conklin Darrell C. |
Novel FGF homolog ZFGF11
|
|
WO2001049849A1
(en)
|
2000-01-05 |
2001-07-12 |
Zymogenetics, Inc. |
Novel fgf homolog zfgf11
|
|
AU5056501A
(en)
|
2000-03-31 |
2001-10-08 |
Nobuyuki Itoh |
Fibroblast growth factor-like molecules and uses thereof
|
|
GB0025144D0
(en)
|
2000-10-13 |
2000-11-29 |
Medical Res Council |
Concatenated nucleic acid sequences
|
|
IL139380A0
(en)
|
2000-10-31 |
2001-11-25 |
Prochon Biotech Ltd |
Active variants of fibroblast growth factor
|
|
US20060223114A1
(en)
|
2001-04-26 |
2006-10-05 |
Avidia Research Institute |
Protein scaffolds and uses thereof
|
|
US20030157561A1
(en)
|
2001-11-19 |
2003-08-21 |
Kolkman Joost A. |
Combinatorial libraries of monomer domains
|
|
US20040018499A1
(en)
|
2001-06-06 |
2004-01-29 |
Lal Preeti G |
Extracellular messengers
|
|
WO2003006501A2
(en)
|
2001-07-11 |
2003-01-23 |
Maxygen Holdings, Ltd. |
G-csf conjugates
|
|
US20040259780A1
(en)
|
2001-07-30 |
2004-12-23 |
Glasebrook Andrew Lawrence |
Method for treating diabetes and obesity
|
|
US20050187150A1
(en)
|
2001-10-31 |
2005-08-25 |
New York University |
Structure-based design and synthesis of FGF inhibitors and FGF modulator compounds
|
|
AU2003201810A1
(en)
|
2002-01-15 |
2003-07-30 |
Eli Lilly And Company |
Method for reducing morbidity and mortality in critically ill patients
|
|
JP2005530687A
(ja)
|
2002-01-31 |
2005-10-13 |
マックス−プランク−ゲゼルシャフト・ツア・フェルデルング・デア・ヴィッセンシャフテン・エー・ファオ |
Ｆｇｆｒアゴニスト
|
|
EP1332761A1
(en)
|
2002-01-31 |
2003-08-06 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Agonists of fibroblast growth factor receptors (FGFR)
|
|
IL149562A0
(en)
|
2002-05-09 |
2002-11-10 |
Prochon Ltd |
Fgf variants and methods for use thereof
|
|
US20040202995A1
(en)
|
2003-04-09 |
2004-10-14 |
Domantis |
Nucleic acids, proteins, and screening methods
|
|
EA008831B1
(ru)
|
2003-06-12 |
2007-08-31 |
Эли Лилли Энд Компани |
Слитые белки аналогов glp-1
|
|
CN1802167A
(zh)
|
2003-06-12 |
2006-07-12 |
伊莱利利公司 |
融合蛋白质
|
|
SI1680140T1
(sl)
|
2003-10-16 |
2011-08-31 |
Imclone Llc |
Inhibitorji receptorja-1 za fibroblastni rastni faktor in metode za zdravljenje z le-temi
|
|
AU2004303783A1
(en)
|
2003-12-10 |
2005-07-07 |
Eli Lilly And Company |
Muteins of fibroblast growth factor 21
|
|
EP1727559A1
(en)
|
2004-01-26 |
2006-12-06 |
Eli Lilly And Company |
Use of fgf-21 and a thiazolidinedione for treating type 2 diabetes
|
|
JP2007531715A
(ja)
|
2004-03-17 |
2007-11-08 |
イーライ リリー アンド カンパニー |
グリコール結合ｆｇｆ−２１化合物
|
|
JP4505631B2
(ja)
|
2004-03-31 |
2010-07-21 |
独立行政法人産業技術総合研究所 |
ヘパラン硫酸糖鎖を付加したヘパリン結合性タンパク質、その製造方法及びそれを含有する医薬組成物
|
|
DK1751184T3
(da)
|
2004-05-13 |
2009-11-23 |
Lilly Co Eli |
FGF-21 fusionsproteiner
|
|
MX2007002616A
(es)
|
2004-09-02 |
2007-05-16 |
Lilly Co Eli |
Muteinas de factor de crecimiento de fibroblasto 21.
|
|
WO2006028714A1
(en)
|
2004-09-02 |
2006-03-16 |
Eli Lilly And Company |
Muteins of fibroblast growth factor 21
|
|
EP1814573B1
(en)
|
2004-10-29 |
2016-03-09 |
ratiopharm GmbH |
Remodeling and glycopegylation of fibroblast growth factor (fgf)
|
|
US7655627B2
(en)
|
2004-12-14 |
2010-02-02 |
Eli Lilly And Company |
Muteins of fibroblast growth factor 21
|
|
US20080261875A1
(en)
|
2005-01-21 |
2008-10-23 |
Eli Lilly And Company |
Method For Treating Cardiovascular Disease
|
|
JP2006246823A
(ja)
|
2005-03-11 |
2006-09-21 |
Kyoto Univ |
造血因子としてのＦｇｆ２１の使用
|
|
WO2006130527A2
(en)
|
2005-05-31 |
2006-12-07 |
Novartis Ag |
Mutations and polymorphisms of fibroblast growth factor receptor 1
|
|
EP2083081A1
(en)
|
2005-07-22 |
2009-07-29 |
Five Prime Therapeutics, Inc. |
Compositions and methods of treating disease with FGFR fusion proteins
|
|
WO2007055789A2
(en)
|
2005-10-31 |
2007-05-18 |
Neose Technologies, Inc. |
Expression of soluble therapeutic proteins
|
|
EP1996215A2
(en)
|
2006-02-28 |
2008-12-03 |
Trustees Of Boston University |
Metabolic regulators and uses thereof
|
|
US9187532B2
(en)
|
2006-07-21 |
2015-11-17 |
Novo Nordisk A/S |
Glycosylation of peptides via O-linked glycosylation sequences
|
|
US20100075375A1
(en)
|
2006-10-03 |
2010-03-25 |
Novo Nordisk A/S |
Methods for the purification of polypeptide conjugates
|
|
JP2010511382A
(ja)
|
2006-12-01 |
2010-04-15 |
エージェンシー フォー サイエンス，テクノロジー アンド リサーチ |
癌関連タンパク質キナーゼ
|
|
PL2068909T3
(pl)
|
2007-03-30 |
2012-09-28 |
Ambrx Inc |
Modyfikowane polipeptydy fgf-21 i ich zastosowanie
|
|
RS57149B1
(sr)
*
|
2007-04-02 |
2018-07-31 |
Genentech Inc |
Kloto-beta agonist antitelo za primenu u tretmanu dijabetes melitusa ili otpornosti na insulin
|
|
WO2008123625A1
(ja)
*
|
2007-04-06 |
2008-10-16 |
National Institute Of Advanced Industrial Science And Technology |
補助因子による受容体の活性化方法並びにリガンド活性の利用方法
|
|
US7537903B2
(en)
*
|
2007-04-23 |
2009-05-26 |
Board Of Regents, The University Of Texas System |
FGF21 upregulates expression of GLUT-1 in a βklotho-dependent manner
|
|
CA2687746A1
(en)
|
2007-05-22 |
2008-12-18 |
Novartis Ag |
Methods of treating, diagnosing and detecting fgf21-associated disorders
|
|
CN101778937A
(zh)
|
2007-06-04 |
2010-07-14 |
诺和诺德公司 |
使用n-乙酰葡糖胺转移酶的o-联糖基化
|
|
JP2010535781A
(ja)
|
2007-08-03 |
2010-11-25 |
イーライ リリー アンド カンパニー |
肥満に対する処置
|
|
TW200936156A
(en)
|
2008-01-28 |
2009-09-01 |
Novartis Ag |
Methods and compositions using Klotho-FGF fusion polypeptides
|
|
EA024751B8
(ru)
|
2008-06-04 |
2020-01-31 |
Амген Инк. |
Мутанты fgf21 и их применение
|
|
WO2010006214A1
(en)
|
2008-07-09 |
2010-01-14 |
Ambrx, Inc. |
Fgf-21 neutralizing antibodies and their uses
|
|
SMT202400036T1
(it)
|
2009-05-05 |
2024-03-13 |
Amgen Inc |
Mutanti fgf21 e loro utilizzi
|
|
US9401875B2
(en)
|
2012-06-01 |
2016-07-26 |
Nippon Telegraph And Telephone Corporation |
Packet transfer processing method and packet transfer processing device
|
|
US9300829B2
(en)
|
2014-04-04 |
2016-03-29 |
Canon Kabushiki Kaisha |
Image reading apparatus and correction method thereof
|