JP2014530001A5 - - Google Patents
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- Publication number
- JP2014530001A5 JP2014530001A5 JP2014531755A JP2014531755A JP2014530001A5 JP 2014530001 A5 JP2014530001 A5 JP 2014530001A5 JP 2014531755 A JP2014531755 A JP 2014531755A JP 2014531755 A JP2014531755 A JP 2014531755A JP 2014530001 A5 JP2014530001 A5 JP 2014530001A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- polypeptide
- tnf
- light chain
- chain variable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161538548P | 2011-09-23 | 2011-09-23 | |
| US61/538,548 | 2011-09-23 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014530001A JP2014530001A (ja) | 2014-11-17 |
| JP2014530001A5 true JP2014530001A5 (enExample) | 2015-11-12 |
Family
ID=47146619
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014531755A Pending JP2014530001A (ja) | 2011-09-23 | 2012-09-19 | 抗腫瘍壊死因子−α剤及びその使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US9399678B2 (enExample) |
| EP (1) | EP2758434A2 (enExample) |
| JP (1) | JP2014530001A (enExample) |
| CN (1) | CN103906765A (enExample) |
| AU (1) | AU2012310328A1 (enExample) |
| BR (1) | BR112014006929A2 (enExample) |
| CA (1) | CA2849409A1 (enExample) |
| SG (2) | SG11201400879SA (enExample) |
| WO (1) | WO2013043070A2 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2849409A1 (en) * | 2011-09-23 | 2013-03-28 | Technophage, Investigacao E Desenvolvimento Em Biotecnologia, Sa | Anti-tumor necrosis factor-alpha agents and uses thereof |
| US9119832B2 (en) | 2014-02-05 | 2015-09-01 | The Regents Of The University Of California | Methods of treating mild brain injury |
| DE102014112212A1 (de) * | 2014-08-26 | 2016-03-03 | Akesion Gmbh | Rekombinante Fusionsproteine zur Vorbeugung oder Behandlung von Adhäsionen bei Geweben oder Organen |
| AU2016209247B2 (en) * | 2015-01-21 | 2021-02-25 | Inhibrx Biosciences, Inc. | Non-immunogenic single domain antibodies |
| AU2016229848A1 (en) * | 2015-03-09 | 2017-10-26 | Oxeia Biopharmaceuticals, Inc. | Methods of treating cognitive impairments or dysfunction |
| CN109562163B (zh) | 2016-02-05 | 2022-04-08 | 得克萨斯大学体系董事会 | Egfl6特异性单克隆抗体及其使用方法 |
| WO2018176089A1 (en) * | 2017-03-27 | 2018-10-04 | Garvan Institute Of Medical Research | Screening methods |
| WO2019032827A1 (en) | 2017-08-09 | 2019-02-14 | Massachusetts Institute Of Technology | PEPTIDE ALBUMIN BINDING CONJUGATES AND METHODS THEREOF |
| AU2018393076B2 (en) * | 2017-12-19 | 2025-11-20 | Surrozen Operating, Inc. | Anti-LRP5/6 antibodies and methods of use |
| CN110066337B (zh) * | 2019-05-16 | 2022-06-21 | 艾柏森(江苏)生物科技有限公司 | 一种抗TNF-α抗体 |
| US11224858B1 (en) | 2020-10-01 | 2022-01-18 | Immunicom, Inc. | Reduced leaching of a ligand |
| KR20230074799A (ko) * | 2020-10-01 | 2023-05-31 | 이뮤니컴 인코포레이티드 | 리간드의 침출 감소 |
| CN118930648B (zh) * | 2024-08-22 | 2025-02-28 | 武汉爱博泰克生物科技有限公司 | 抗人pax8蛋白的兔单克隆抗体、抗体偶联物及其应用 |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE37983T1 (de) | 1982-04-22 | 1988-11-15 | Ici Plc | Mittel mit verzoegerter freigabe. |
| GB8308235D0 (en) | 1983-03-25 | 1983-05-05 | Celltech Ltd | Polypeptides |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US4544545A (en) | 1983-06-20 | 1985-10-01 | Trustees University Of Massachusetts | Liposomes containing modified cholesterol for organ targeting |
| US5807715A (en) | 1984-08-27 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and transformed mammalian lymphocyte cells for producing functional antigen-binding protein including chimeric immunoglobulin |
| US5128326A (en) | 1984-12-06 | 1992-07-07 | Biomatrix, Inc. | Drug delivery systems based on hyaluronans derivatives thereof and their salts and methods of producing same |
| US5336603A (en) | 1987-10-02 | 1994-08-09 | Genentech, Inc. | CD4 adheson variants |
| SE509359C2 (sv) | 1989-08-01 | 1999-01-18 | Cemu Bioteknik Ab | Användning av stabiliserade protein- eller peptidkonjugat för framställning av ett läkemedel |
| US6267964B1 (en) * | 1989-08-01 | 2001-07-31 | Affibody Technology Sweden Ab | Stabilized protein or peptide conjugates able to bond albumin having extended biological half-lives |
| WO1991005548A1 (en) | 1989-10-10 | 1991-05-02 | Pitman-Moore, Inc. | Sustained release composition for macromolecular proteins |
| US5013556A (en) | 1989-10-20 | 1991-05-07 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| CA2071867A1 (en) | 1989-11-06 | 1991-05-07 | Edith Mathiowitz | Method for producing protein microspheres |
| SE9002213D0 (sv) | 1990-06-21 | 1990-06-21 | Hightech Receptor Ab | Albumin binding proteins |
| FI85768C (fi) | 1990-07-04 | 1992-05-25 | Valtion Teknillinen | Foerfarande foer utfoerning av ytplasmonresonansmaetning samt i foerfarandet anvaendbar givare. |
| EP0517930B1 (en) | 1991-06-08 | 1995-05-24 | Hewlett-Packard GmbH | Method and apparatus for detecting the presence and/or concentration of biomolecules |
| US5912015A (en) | 1992-03-12 | 1999-06-15 | Alkermes Controlled Therapeutics, Inc. | Modulated release from biocompatible polymers |
| WO1993023434A2 (en) | 1992-05-19 | 1993-11-25 | Xoma Corporation | Bpi-immunoglobulin fusion proteins |
| US6962686B2 (en) | 1994-10-12 | 2005-11-08 | California Institute Of Technology | Cell-specific gene delivery vehicles |
| CA2207961A1 (en) | 1995-01-05 | 1996-07-11 | Robert J. Levy | Surface-modified nanoparticles and method of making and using same |
| AU710347B2 (en) | 1995-08-31 | 1999-09-16 | Alkermes Controlled Therapeutics, Inc. | Composition for sustained release of an agent |
| GB9623820D0 (en) | 1996-11-16 | 1997-01-08 | Secr Defence | Surface plasma resonance sensor |
| US6277375B1 (en) | 1997-03-03 | 2001-08-21 | Board Of Regents, The University Of Texas System | Immunoglobulin-like domains with increased half-lives |
| DE69833755T2 (de) * | 1997-05-21 | 2006-12-28 | Biovation Ltd. | Verfahren zur herstellung von nicht-immunogenen proteinen |
| US5989463A (en) | 1997-09-24 | 1999-11-23 | Alkermes Controlled Therapeutics, Inc. | Methods for fabricating polymer-based controlled release devices |
| SE512663C2 (sv) | 1997-10-23 | 2000-04-17 | Biogram Ab | Inkapslingsförfarande för aktiv substans i en bionedbrytbar polymer |
| WO1999060382A1 (de) | 1998-05-20 | 1999-11-25 | Graffinity Pharmaceutical Design Gmbh | Spr-sensor zur gleichzeitigen erfassung einer vielzahl von in fluider form vorliegenden proben |
| US6289286B1 (en) | 1998-05-29 | 2001-09-11 | Biacore Ab | Surface regeneration of biosensors and characterization of biomolecules associated therewith |
| US6311415B1 (en) | 1998-09-14 | 2001-11-06 | Lind Shoe Company | Bowling shoe with replaceable tip |
| US6319691B1 (en) | 1999-06-15 | 2001-11-20 | Usa Universe Bioengineering, Inc. | Fusion proteins comprising IFN-alpha2b and TM-alpha1 |
| US20040001827A1 (en) | 2002-06-28 | 2004-01-01 | Dennis Mark S. | Serum albumin binding peptides for tumor targeting |
| ES2270893T3 (es) | 1999-12-24 | 2007-04-16 | Genentech, Inc. | Procedimiento y composiciones para prolongar la vida media de compuestos bioactivos. |
| EP1517921B1 (en) * | 2002-06-28 | 2006-06-07 | Domantis Limited | Dual specific ligands with increased serum half-life |
| JP5634008B2 (ja) | 2004-04-06 | 2014-12-03 | アフィボディ・アーベー | 新規の使用および方法 |
| RU2464276C2 (ru) | 2005-05-18 | 2012-10-20 | Аблинкс Н.В. | Улучшенные нанотела против фактора некроза опухоли-альфа |
| EP1987064A4 (en) * | 2006-02-01 | 2010-04-07 | Arana Therapeutics Ltd | DOMAIN ANTIBODY CONSTRUCT |
| WO2010017595A1 (en) * | 2008-08-14 | 2010-02-18 | Arana Therapeutics Limited | Variant domain antibodies |
| EP2362767B1 (en) | 2008-10-29 | 2017-12-06 | Ablynx N.V. | Formulations of single domain antigen binding molecules |
| US20110195396A1 (en) | 2010-02-10 | 2011-08-11 | Selinfreund Richard H | Chewable compositions for the stabilization of diagnostic biomarkers |
| CN106039306A (zh) * | 2011-03-30 | 2016-10-26 | 埃博灵克斯股份有限公司 | 使用针对TNFα的单结构域抗体治疗免疫病症的方法 |
| CA2849409A1 (en) * | 2011-09-23 | 2013-03-28 | Technophage, Investigacao E Desenvolvimento Em Biotecnologia, Sa | Anti-tumor necrosis factor-alpha agents and uses thereof |
-
2012
- 2012-09-19 CA CA2849409A patent/CA2849409A1/en not_active Abandoned
- 2012-09-19 SG SG11201400879SA patent/SG11201400879SA/en unknown
- 2012-09-19 AU AU2012310328A patent/AU2012310328A1/en not_active Abandoned
- 2012-09-19 JP JP2014531755A patent/JP2014530001A/ja active Pending
- 2012-09-19 SG SG10201504605RA patent/SG10201504605RA/en unknown
- 2012-09-19 BR BR112014006929A patent/BR112014006929A2/pt active Search and Examination
- 2012-09-19 WO PCT/PT2012/000035 patent/WO2013043070A2/en not_active Ceased
- 2012-09-19 EP EP12783676.5A patent/EP2758434A2/en not_active Ceased
- 2012-09-19 US US14/346,151 patent/US9399678B2/en not_active Expired - Fee Related
- 2012-09-19 CN CN201280053629.1A patent/CN103906765A/zh active Pending
-
2016
- 2016-07-22 US US15/217,495 patent/US20170137510A1/en not_active Abandoned
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