|
US8212004B2
(en)
|
1999-03-02 |
2012-07-03 |
Human Genome Sciences, Inc. |
Neutrokine-alpha fusion proteins
|
|
US6812327B1
(en)
|
1996-10-25 |
2004-11-02 |
Human Genome Sciences, Inc. |
Neutrokine-alpha polypeptides
|
|
US6660843B1
(en)
*
|
1998-10-23 |
2003-12-09 |
Amgen Inc. |
Modified peptides as therapeutic agents
|
|
JP2003533187A
(ja)
*
|
2000-05-03 |
2003-11-11 |
アムジエン・インコーポレーテツド |
治療薬としてのFcドメインを含む修飾ペプチド
|
|
US7879328B2
(en)
|
2000-06-16 |
2011-02-01 |
Human Genome Sciences, Inc. |
Antibodies that immunospecifically bind to B lymphocyte stimulator
|
|
DE60143798D1
(de)
|
2000-06-16 |
2011-02-17 |
Cambridge Antibody Tech |
Immunspezifisch bindende antikörper gegen blys
|
|
EP2267015A3
(en)
|
2000-08-18 |
2011-04-20 |
Human Genome Sciences, Inc. |
Binding polypeptides for B lymphocyte stimulator protein (BLyS)
|
|
WO2002016411A2
(en)
|
2000-08-18 |
2002-02-28 |
Human Genome Sciences, Inc. |
Binding polypeptides and methods based thereon
|
|
US7658924B2
(en)
|
2001-10-11 |
2010-02-09 |
Amgen Inc. |
Angiopoietin-2 specific binding agents
|
|
US7205275B2
(en)
*
|
2001-10-11 |
2007-04-17 |
Amgen Inc. |
Methods of treatment using specific binding agents of human angiopoietin-2
|
|
US7138370B2
(en)
|
2001-10-11 |
2006-11-21 |
Amgen Inc. |
Specific binding agents of human angiopoietin-2
|
|
US7772188B2
(en)
|
2003-01-28 |
2010-08-10 |
Ironwood Pharmaceuticals, Inc. |
Methods and compositions for the treatment of gastrointestinal disorders
|
|
US20050025763A1
(en)
*
|
2003-05-08 |
2005-02-03 |
Protein Design Laboratories, Inc. |
Therapeutic use of anti-CS1 antibodies
|
|
MXPA06000508A
(es)
|
2003-07-18 |
2006-04-05 |
Amgen Inc |
Agentes de union especifica al factor del crecimiento de los hepatocitos.
|
|
EP1734963A4
(en)
|
2004-04-02 |
2008-06-18 |
Merck & Co Inc |
METHOD FOR TREATING PEOPLE WITH METABOLIC AND ANTHROPOMETRIC DISORDER
|
|
EA011866B1
(ru)
*
|
2004-10-19 |
2009-06-30 |
Амджен Инк. |
Агенты, специфически связывающие ангиопоэтин-2
|
|
AU2011203387B2
(en)
*
|
2004-12-21 |
2015-03-19 |
Astrazeneca Ab |
Antibodies directed to angiopoietin-2 and uses thereof
|
|
WO2006068953A2
(en)
*
|
2004-12-21 |
2006-06-29 |
Astrazeneca Ab |
Antibodies directed to angiopoietin-2 and uses thereof
|
|
MY146381A
(en)
|
2004-12-22 |
2012-08-15 |
Amgen Inc |
Compositions and methods relating relating to anti-igf-1 receptor antibodies
|
|
US7759080B2
(en)
*
|
2004-12-27 |
2010-07-20 |
National University Corporation Okayama University |
Method of determining pregnancy toxemia
|
|
WO2006078766A2
(en)
*
|
2005-01-19 |
2006-07-27 |
University Of Connecticut |
Methods and compositions for metastatic tumor screening
|
|
EP1846451B1
(en)
*
|
2005-01-24 |
2013-05-15 |
Medimmune Limited |
Human antibodies against human ngf
|
|
JP2008533115A
(ja)
*
|
2005-03-18 |
2008-08-21 |
ドマンティス リミテッド |
カンジダ抗原に対する抗体
|
|
ES2776657T3
(es)
|
2005-06-14 |
2020-07-31 |
Amgen Inc |
Formulaciones de proteínas autotamponantes
|
|
US9168286B2
(en)
|
2005-10-13 |
2015-10-27 |
Human Genome Sciences, Inc. |
Methods and compositions for use in treatment of patients with autoantibody positive disease
|
|
EP1962903B1
(en)
*
|
2005-12-15 |
2013-03-13 |
MedImmune Limited |
Combination of angiopoietin-2 antagonist and of vegf-a, kdr and/or fltl antagonist for treating cancer
|
|
AR059066A1
(es)
*
|
2006-01-27 |
2008-03-12 |
Amgen Inc |
Combinaciones del inhibidor de la angiopoyetina -2 (ang2) y el inhibidor del factor de crecimiento endotelial vascular (vegf)
|
|
US8278421B2
(en)
*
|
2006-03-20 |
2012-10-02 |
Xoma Techolology Ltd. |
Human antibodies specific for gastrin materials and methods
|
|
US8211649B2
(en)
|
2006-03-31 |
2012-07-03 |
Human Genome Sciences, Inc. |
Methods of diagnosing and prognosing hodgkin's lymphoma
|
|
AR065368A1
(es)
*
|
2007-02-15 |
2009-06-03 |
Astrazeneca Ab |
Anticuerpos para moleculas de ige
|
|
WO2008108986A2
(en)
*
|
2007-03-02 |
2008-09-12 |
Amgen Inc. |
Methods and compositions for treating tumor diseases
|
|
US8969514B2
(en)
|
2007-06-04 |
2015-03-03 |
Synergy Pharmaceuticals, Inc. |
Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
|
|
MX354786B
(es)
|
2007-06-04 |
2018-03-21 |
Synergy Pharmaceuticals Inc |
Agonistas de guanilato ciclasa utiles para el tratamiento de trastornos gastrointestinales, inflamacion, cancer y otros trastornos.
|
|
MX2010001918A
(es)
|
2007-08-21 |
2010-03-11 |
Amgen Inc |
Proteinas enlazadas al antigeno humano de celula de cepa mcdonough de felino.
|
|
MX2010002683A
(es)
|
2007-09-14 |
2010-03-26 |
Amgen Inc |
Poblaciones de anticuerpos homogeneos.
|
|
WO2009043049A2
(en)
|
2007-09-27 |
2009-04-02 |
Amgen Inc. |
Pharmaceutical formulations
|
|
WO2009064838A1
(en)
|
2007-11-15 |
2009-05-22 |
Amgen, Inc. |
Aqueous formulation of erythropoiesis stimulating protein stablised by antioxidants for parenteral administration
|
|
US20090162359A1
(en)
|
2007-12-21 |
2009-06-25 |
Christian Klein |
Bivalent, bispecific antibodies
|
|
US8227577B2
(en)
*
|
2007-12-21 |
2012-07-24 |
Hoffman-La Roche Inc. |
Bivalent, bispecific antibodies
|
|
US9266967B2
(en)
|
2007-12-21 |
2016-02-23 |
Hoffmann-La Roche, Inc. |
Bivalent, bispecific antibodies
|
|
US8454960B2
(en)
|
2008-01-03 |
2013-06-04 |
The Scripps Research Institute |
Multispecific antibody targeting and multivalency through modular recognition domains
|
|
US8557242B2
(en)
|
2008-01-03 |
2013-10-15 |
The Scripps Research Institute |
ERBB2 antibodies comprising modular recognition domains
|
|
US8557243B2
(en)
|
2008-01-03 |
2013-10-15 |
The Scripps Research Institute |
EFGR antibodies comprising modular recognition domains
|
|
SG189769A1
(en)
|
2008-01-03 |
2013-05-31 |
Scripps Research Inst |
Antibody targeting through a modular recognition domain
|
|
US8574577B2
(en)
|
2008-01-03 |
2013-11-05 |
The Scripps Research Institute |
VEGF antibodies comprising modular recognition domains
|
|
RU2509085C2
(ru)
|
2008-01-28 |
2014-03-10 |
Медиммун Лимитед |
Стабилизированные антитела против ангиопоэтина-2 и их применение
|
|
JO2913B1
(en)
*
|
2008-02-20 |
2015-09-15 |
امجين إنك, |
Antibodies directed towards angiopoietin-1 and angiopoietin-2 proteins and their uses
|
|
WO2010011242A2
(en)
*
|
2008-03-24 |
2010-01-28 |
Beth Israel Deaconess Medical Center |
Methods and compositions for the treatment and diagnoisis of systemic anthrax infection
|
|
US9328172B2
(en)
*
|
2008-04-05 |
2016-05-03 |
Single Cell Technology, Inc. |
Method of obtaining antibodies of interest and nucleotides encoding same
|
|
CA2726917C
(en)
|
2008-06-04 |
2018-06-26 |
Synergy Pharmaceuticals Inc. |
Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
|
|
EP2307456B1
(en)
|
2008-06-27 |
2014-10-15 |
Amgen Inc. |
Ang-2 inhibition to treat multiple sclerosis
|
|
EP2321341B1
(en)
|
2008-07-16 |
2017-02-22 |
Synergy Pharmaceuticals Inc. |
Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
|
|
AU2013203517B2
(en)
*
|
2008-10-08 |
2015-02-05 |
F. Hoffmann-La Roche Ag |
Bispecific anti-VEGF/anti-ANG-2 antibodies
|
|
US8268314B2
(en)
|
2008-10-08 |
2012-09-18 |
Hoffmann-La Roche Inc. |
Bispecific anti-VEGF/anti-ANG-2 antibodies
|
|
US8410284B2
(en)
|
2008-10-22 |
2013-04-02 |
Merck Sharp & Dohme Corp |
Cyclic benzimidazole derivatives useful as anti-diabetic agents
|
|
CA2741672A1
(en)
|
2008-10-31 |
2010-05-06 |
Merck Sharp & Dohme Corp. |
Novel cyclic benzimidazole derivatives useful anti-diabetic agents
|
|
AU2013203458B2
(en)
*
|
2008-12-16 |
2015-07-23 |
F. Hoffmann-La Roche Ag |
Antibodies against human Angiopoietin 2
|
|
US8133979B2
(en)
|
2008-12-16 |
2012-03-13 |
Hoffmann-La Roche Inc. |
Antibodies against human angiopoietin 2
|
|
PE20120591A1
(es)
*
|
2009-04-02 |
2012-05-23 |
Roche Glycart Ag |
Anticuerpos multiespecificos que comprenden anticuerpos de longitud completa y fragmentos fab de cadena sencilla
|
|
CN102369214B
(zh)
|
2009-04-07 |
2019-04-12 |
罗氏格黎卡特股份公司 |
三价、双特异性抗体
|
|
US9676845B2
(en)
|
2009-06-16 |
2017-06-13 |
Hoffmann-La Roche, Inc. |
Bispecific antigen binding proteins
|
|
JO3182B1
(ar)
*
|
2009-07-29 |
2018-03-08 |
Regeneron Pharma |
مضادات حيوية بشرية عالية الالفة مع تولد الاوعية البشرية - 2
|
|
US8980268B2
(en)
|
2009-07-29 |
2015-03-17 |
Regeneron Pharamceuticals, Inc. |
Methods for treating cancer by administering an anti-Ang-2 antibody
|
|
US20120189635A1
(en)
|
2009-07-29 |
2012-07-26 |
Regeneron Pharmaceuticals, Inc. |
Methods for Treating or Preventing Malaria by Administering an Antibody that Specifically Binds Angiopoietin-2 (Ang-2)
|
|
TH121482A
(th)
|
2009-08-19 |
2013-02-28 |
นางสาวปัณณพัฒน์ เหลืองธาตุทอง |
องค์ประกอบทางเภสัชกรรมที่ประกอบด้วยอนุพันธ์ของควิโนลีน
|
|
WO2011034605A2
(en)
|
2009-09-16 |
2011-03-24 |
Genentech, Inc. |
Coiled coil and/or tether containing protein complexes and uses thereof
|
|
MX344382B
(es)
|
2009-10-23 |
2016-12-14 |
Amgen Inc * |
Adaptador de vial y sistema.
|
|
KR101688522B1
(ko)
*
|
2009-12-15 |
2016-12-21 |
삼성전자주식회사 |
안지오포이에틴-2에 특이적으로 결합하는 항체 및 그의 용도
|
|
AU2011218830B2
(en)
|
2010-02-25 |
2014-07-24 |
Merck Sharp & Dohme Corp. |
Novel cyclic benzimidazole derivatives useful anti-diabetic agents
|
|
AR080793A1
(es)
|
2010-03-26 |
2012-05-09 |
Roche Glycart Ag |
Anticuerpos biespecificos
|
|
TWI426920B
(zh)
|
2010-03-26 |
2014-02-21 |
Hoffmann La Roche |
雙專一性、雙價抗-vegf/抗-ang-2抗體
|
|
HUE026173T2
(en)
|
2010-06-07 |
2016-05-30 |
Amgen Inc |
pharmaceutical Pump
|
|
US20120100166A1
(en)
|
2010-07-15 |
2012-04-26 |
Zyngenia, Inc. |
Ang-2 Binding Complexes and Uses Thereof
|
|
RU2013110875A
(ru)
|
2010-08-24 |
2014-09-27 |
Ф.Хоффманн-Ля Рош Аг |
БИСПЕЦИФИЧЕСКИЕ АНТИТЕЛА, СОДЕРЖАЩИЕ СТАБИЛИЗИРОВАННЫЙ ДИСУЛЬФИДОМ ФРАГМЕНТ Fv
|
|
US9616097B2
(en)
|
2010-09-15 |
2017-04-11 |
Synergy Pharmaceuticals, Inc. |
Formulations of guanylate cyclase C agonists and methods of use
|
|
JP5766296B2
(ja)
|
2010-12-23 |
2015-08-19 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
ポリペプチド−ポリヌクレオチド複合体、およびエフェクター成分の標的化された送達におけるその使用
|
|
CA2826649C
(en)
|
2011-02-25 |
2016-07-26 |
Merck Sharp & Dohme Corp. |
Novel cyclic azabenzimidazole derivatives useful as anti-diabetic agents
|
|
JP5764677B2
(ja)
|
2011-02-28 |
2015-08-19 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
抗原結合タンパク質
|
|
CA2824824A1
(en)
|
2011-02-28 |
2012-09-07 |
F. Hoffmann-La Roche Ag |
Monovalent antigen binding proteins
|
|
AU2012236573B2
(en)
|
2011-03-31 |
2016-06-02 |
Amgen Inc. |
Vial adapter and system
|
|
WO2012137993A1
(en)
*
|
2011-04-05 |
2012-10-11 |
Neopharm Co., Ltd. |
Antibodies against angiopoietins 1 and 2, and their use
|
|
TR201905991T4
(tr)
|
2011-04-20 |
2019-05-21 |
Amgen Inc |
Oto enjektör aparatı.
|
|
EP2714738B1
(en)
|
2011-05-24 |
2018-10-10 |
Zyngenia, Inc. |
Multivalent and monovalent multispecific complexes and their uses
|
|
EP3045188B1
(en)
|
2011-10-14 |
2020-12-23 |
Amgen Inc. |
Injector and method of assembly
|
|
AU2013212587B2
(en)
|
2012-01-23 |
2017-07-20 |
Regeneron Pharmaceuticals, Inc. |
Stabilized formulations containing anti-Ang2 antibodies
|
|
MX2014009565A
(es)
|
2012-02-10 |
2014-11-10 |
Genentech Inc |
Anticuerpos monocatenarios y otros heteromultimeros.
|
|
AR090263A1
(es)
|
2012-03-08 |
2014-10-29 |
Hoffmann La Roche |
Terapia combinada de anticuerpos contra el csf-1r humano y las utilizaciones de la misma
|
|
HUE044263T2
(hu)
|
2012-03-30 |
2019-10-28 |
Boehringer Ingelheim Int |
ANG2-kötõ molekulák
|
|
RU2015100656A
(ru)
|
2012-06-27 |
2016-08-20 |
Ф. Хоффманн-Ля Рош Аг |
Способ получения конъюгатов fc-фрагмента антитела, включающих по меньшей мере одну связывающую группировку, которая специфически связывается с мишенью, и их применения
|
|
JP6203838B2
(ja)
|
2012-06-27 |
2017-09-27 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
少なくとも2つの異なる結合実体を含む、テーラーメイドの高度に選択的かつ多重特異的なターゲティング実体を選択および作製するための方法、ならびにその使用
|
|
EP2872534B1
(en)
|
2012-07-13 |
2018-08-08 |
Roche Glycart AG |
Bispecific anti-vegf/anti-ang-2 antibodies and their use in the treatment of ocular vascular diseases
|
|
RU2015106909A
(ru)
|
2012-08-02 |
2016-09-27 |
Мерк Шарп И Доум Корп. |
Антидиабетические трициклические соединения
|
|
US8883979B2
(en)
*
|
2012-08-31 |
2014-11-11 |
Bayer Healthcare Llc |
Anti-prolactin receptor antibody formulations
|
|
EP2922590B1
(en)
|
2012-11-21 |
2020-02-05 |
Amgen Inc. |
Drug delivery device
|
|
UY35148A
(es)
|
2012-11-21 |
2014-05-30 |
Amgen Inc |
Immunoglobulinas heterodiméricas
|
|
WO2014100143A2
(en)
*
|
2012-12-20 |
2014-06-26 |
Medimmune, Llc |
Liquid antibody formulation with improved aggregation properties
|
|
WO2014108854A1
(en)
|
2013-01-09 |
2014-07-17 |
Fusimab Ltd. |
Monospecific anti-hgf and anti-ang2 antibodies and bispecific anti-hgf/anti-ang2 antibodies
|
|
BR112015019836A2
(pt)
|
2013-02-22 |
2017-07-18 |
Merck Sharp & Dohme |
composto, composição farmacêutica, e, uso de um composto
|
|
EP2970119B1
(en)
|
2013-03-14 |
2021-11-03 |
Merck Sharp & Dohme Corp. |
Novel indole derivatives useful as anti-diabetic agents
|
|
US10092703B2
(en)
|
2013-03-15 |
2018-10-09 |
Amgen Inc. |
Drug cassette, autoinjector, and autoinjector system
|
|
SG11201507417RA
(en)
|
2013-03-15 |
2015-10-29 |
Amgen Inc |
Body contour adaptable autoinjector device
|
|
JP2016514671A
(ja)
|
2013-03-15 |
2016-05-23 |
シナジー ファーマシューティカルズ インコーポレイテッド |
グアニル酸シクラーゼのアゴニストおよびその使用
|
|
TWI614041B
(zh)
|
2013-03-15 |
2018-02-11 |
安美基公司 |
用於注射器之匣盒
|
|
EP3424530A1
(en)
|
2013-03-15 |
2019-01-09 |
Zyngenia, Inc. |
Multivalent and monovalent multispecific complexes and their uses
|
|
WO2014151200A2
(en)
|
2013-03-15 |
2014-09-25 |
Synergy Pharmaceuticals Inc. |
Compositions useful for the treatment of gastrointestinal disorders
|
|
US9708375B2
(en)
|
2013-03-15 |
2017-07-18 |
Amgen Inc. |
Inhibitory polypeptides specific to WNT inhibitors
|
|
EP2976117B1
(en)
|
2013-03-22 |
2020-12-30 |
Amgen Inc. |
Injector and method of assembly
|
|
ES2687968T3
(es)
|
2013-05-14 |
2018-10-30 |
Eisai R&D Management Co., Ltd. |
Biomarcadores para pronosticar y evaluar la reactividad de sujetos con cáncer de endometrio a compuestos con lenvatinib
|
|
CN103333247B
(zh)
*
|
2013-05-30 |
2014-10-08 |
北京东方百泰生物科技有限公司 |
新型抗vegfr2的单克隆抗体及其制备与应用
|
|
CN105764916B
(zh)
|
2013-06-05 |
2021-05-18 |
博士医疗爱尔兰有限公司 |
鸟苷酸环化酶c的超纯激动剂、制备和使用所述激动剂的方法
|
|
KR102060187B1
(ko)
|
2013-07-19 |
2019-12-27 |
삼성전자주식회사 |
Vegf-c, vegf-d 및/또는 안지오포이에틴-2를 동시에 저해하는 융합 폴리펩타이드 및 이의 용도
|
|
KR102118691B1
(ko)
*
|
2013-09-05 |
2020-06-04 |
삼성전자주식회사 |
항 Ang2 항체를 포함하는 혈관누수 차단제
|
|
WO2015035215A1
(en)
|
2013-09-05 |
2015-03-12 |
Amgen Inc. |
Fc-containing molecules exhibiting predictable, consistent, and reproducible glycoform profiles
|
|
WO2015051496A1
(en)
|
2013-10-08 |
2015-04-16 |
Merck Sharp & Dohme Corp. |
Antidiabetic tricyclic compounds
|
|
BR112016006929A2
(pt)
|
2013-10-11 |
2017-09-19 |
Hoffmann La Roche |
Anticorpo, ácido nucleico, vetor de expressão, célula hospedeira, métodos de preparação de anticorpo, de tratamento de pacientes e de geração de um anticorpo, composição farmacêutica e uso do anticorpo
|
|
EP3957345B1
(en)
|
2013-10-24 |
2025-12-10 |
Amgen Inc. |
Drug delivery system with temperature-sensitive control
|
|
CA2920894C
(en)
|
2013-10-24 |
2023-03-14 |
Amgen Inc. |
Injector and method of assembly
|
|
US10994112B2
(en)
|
2014-02-05 |
2021-05-04 |
Amgen Inc. |
Drug delivery system with electromagnetic field generator
|
|
MX388536B
(es)
|
2014-05-07 |
2025-03-20 |
Amgen Inc |
Autoinyector con elementos reductores del shock.
|
|
US10156562B2
(en)
|
2014-05-16 |
2018-12-18 |
Amgen Inc. |
Assay for detecting Th1 and Th2 cell populations
|
|
CN106470717B
(zh)
|
2014-06-03 |
2020-09-11 |
安姆根有限公司 |
药物递送系统和使用方法
|
|
KR20230043234A
(ko)
|
2014-08-28 |
2023-03-30 |
에자이 알앤드디 매니지먼트 가부시키가이샤 |
고순도의 퀴놀린 유도체 및 이를 제조하는 방법
|
|
AU2015332557B2
(en)
|
2014-10-14 |
2020-05-14 |
Amgen Inc. |
Drug injection device with visual and audio indicators
|
|
US20170233467A1
(en)
|
2014-10-17 |
2017-08-17 |
Amgen Inc. |
Antibodies Directed to Angiopoietin-1 and Angiopoietin-2 for Ocular Therapies
|
|
WO2016087416A1
(en)
|
2014-12-03 |
2016-06-09 |
F. Hoffmann-La Roche Ag |
Multispecific antibodies
|
|
EP3848072A1
(en)
|
2014-12-19 |
2021-07-14 |
Amgen Inc. |
Drug delivery device with proximity sensor
|
|
ES2785311T3
(es)
|
2014-12-19 |
2020-10-06 |
Amgen Inc |
Dispositivo de administración de fármacos con botón móvil o campo de interfaz de usuario
|
|
CA3069716C
(en)
|
2015-02-17 |
2021-11-09 |
Amgen Inc. |
Drug delivery device with vacuum assisted securement and/or feedback
|
|
LT3263106T
(lt)
|
2015-02-25 |
2024-01-10 |
Eisai R&D Management Co., Ltd. |
Chinolino darinių kartumo sumažinimo būdas
|
|
EP3261690B1
(en)
|
2015-02-27 |
2021-12-15 |
Amgen Inc. |
Drug delivery device having a needle guard mechanism with a tunable threshold of resistance to needle guard movement
|
|
KR102662228B1
(ko)
|
2015-03-04 |
2024-05-02 |
머크 샤프 앤드 돔 코포레이션 |
암을 치료하기 위한 pd-1 길항제 및 vegfr/fgfr/ret 티로신 키나제 억제제의 조합
|
|
MX373231B
(es)
|
2015-06-16 |
2020-05-08 |
Eisai R&D Man Co Ltd |
Agente anticancerigeno.
|
|
MA42613A
(fr)
|
2015-08-13 |
2018-06-20 |
Amgen Inc |
Filtration en profondeur chargée de protéines de liaison à un antigène
|
|
CA2994925C
(en)
|
2015-08-20 |
2023-08-29 |
Eisai R&D Management Co., Ltd. |
Tumor therapeutic agent
|
|
WO2017039786A1
(en)
|
2015-09-02 |
2017-03-09 |
Amgen Inc. |
Syringe assembly adapter for a syringe
|
|
WO2017070608A1
(en)
*
|
2015-10-23 |
2017-04-27 |
Eureka Therapeutics, Inc. |
Antibody/t-cell receptor chimeric constructs and uses thereof
|
|
EP3383914A4
(en)
*
|
2015-12-02 |
2019-10-30 |
Agenus Inc. |
ANTI-OX40 ANTIBODIES AND METHOD OF USE THEREOF
|
|
US20180363000A1
(en)
*
|
2015-12-14 |
2018-12-20 |
The Trustees Of The University Of Pennsylvania |
Aav-anti pcsk9 antibody constructs and uses thereof
|
|
EA201891164A1
(ru)
|
2015-12-16 |
2018-11-30 |
Ридженерон Фармасьютикалз, Инк. |
Композиции и способы получения белковых микрочастиц
|
|
US11154661B2
(en)
|
2016-01-06 |
2021-10-26 |
Amgen Inc. |
Auto-injector with signaling electronics
|
|
WO2017160799A1
(en)
|
2016-03-15 |
2017-09-21 |
Amgen Inc. |
Reducing probability of glass breakage in drug delivery devices
|
|
AU2017250191A1
(en)
*
|
2016-04-13 |
2018-11-08 |
Orimabs Ltd. |
Anti-PSMA antibodies and use thereof
|
|
WO2017189089A1
(en)
|
2016-04-29 |
2017-11-02 |
Amgen Inc. |
Drug delivery device with messaging label
|
|
US11389588B2
(en)
|
2016-05-02 |
2022-07-19 |
Amgen Inc. |
Syringe adapter and guide for filling an on-body injector
|
|
AU2017263558B2
(en)
|
2016-05-13 |
2022-12-22 |
Amgen Inc. |
Vial sleeve assembly
|
|
EP3458988B1
(en)
|
2016-05-16 |
2023-10-18 |
Amgen Inc. |
Data encryption in medical devices with limited computational capability
|
|
WO2017209899A1
(en)
|
2016-06-03 |
2017-12-07 |
Amgen Inc. |
Impact testing apparatuses and methods for drug delivery devices
|
|
WO2018004842A1
(en)
|
2016-07-01 |
2018-01-04 |
Amgen Inc. |
Drug delivery device having minimized risk of component fracture upon impact events
|
|
US20190328965A1
(en)
|
2016-08-17 |
2019-10-31 |
Amgen Inc. |
Drug delivery device with placement detection
|
|
KR102543878B1
(ko)
|
2016-08-23 |
2023-06-14 |
메디뮨 리미티드 |
항-vegf-a 및 항-ang2 항체 및 이의 용도
|
|
US11072602B2
(en)
|
2016-12-06 |
2021-07-27 |
Merck Sharp & Dohme Corp. |
Antidiabetic heterocyclic compounds
|
|
WO2018118670A1
(en)
|
2016-12-20 |
2018-06-28 |
Merck Sharp & Dohme Corp. |
Antidiabetic spirochroman compounds
|
|
WO2018114728A1
(en)
|
2016-12-20 |
2018-06-28 |
F. Hoffmann-La Roche Ag |
Combination therapy with a bispecific anti-ang2/vegf antibody and a bispecific anti-her2 antibody
|
|
CN109071656B
(zh)
|
2017-01-05 |
2021-05-18 |
璟尚生物制药公司 |
检查点调节物拮抗剂
|
|
JP2020503976A
(ja)
|
2017-01-17 |
2020-02-06 |
アムジエン・インコーポレーテツド |
注入デバイスならびに関連する使用および組立方法
|
|
US12303505B2
(en)
|
2017-02-08 |
2025-05-20 |
Eisai R&D Management Co., Ltd. |
Tumor-treating pharmaceutical composition
|
|
EP3582829A1
(en)
|
2017-02-17 |
2019-12-25 |
Amgen Inc. |
Insertion mechanism for drug delivery device
|
|
MX2019009625A
(es)
|
2017-02-17 |
2019-10-09 |
Amgen Inc |
Dispositivo de administracion de farmacos con trayectoria de flujo de fluido esteril y metodo relacionado de ensamblaje.
|
|
EP3592403B1
(en)
|
2017-03-06 |
2025-08-20 |
Amgen Inc. |
Drug delivery device with activation prevention feature
|
|
CA3052482A1
(en)
|
2017-03-07 |
2018-09-13 |
Amgen Inc. |
Needle insertion by overpressure
|
|
AU2018230486B2
(en)
|
2017-03-09 |
2023-05-11 |
Amgen Inc. |
Insertion mechanism for drug delivery device
|
|
JP7672196B2
(ja)
|
2017-03-14 |
2025-05-07 |
アムジエン・インコーポレーテツド |
細胞培養において産生される抗体の総非フコシル化グリコフォームの調節
|
|
CN118743804A
(zh)
|
2017-03-28 |
2024-10-08 |
美国安进公司 |
柱塞杆和注射器组件系统以及方法
|
|
BR112019023064A2
(pt)
|
2017-05-16 |
2020-06-09 |
Eisai R&D Man Co Ltd |
tratamento de carcinoma hepatocelular
|
|
AU2018280054B2
(en)
|
2017-06-08 |
2023-07-13 |
Amgen Inc. |
Syringe assembly for a drug delivery device and method of assembly
|
|
CA3066399A1
(en)
|
2017-06-08 |
2018-12-13 |
Amgen Inc. |
Torque driven drug delivery device
|
|
AU2018288604B2
(en)
|
2017-06-22 |
2023-12-21 |
Amgen Inc. |
Device activation impact/shock reduction
|
|
MA49461A
(fr)
|
2017-06-23 |
2020-04-29 |
Amgen Inc |
Dispositif électronique d'administration de médicament comprenant un bouchon activé par un ensemble commutateur
|
|
MA49562A
(fr)
|
2017-07-14 |
2020-05-20 |
Amgen Inc |
Système d'insertion-rétractation d'aiguille présentant un système à ressort en double torsion
|
|
US11672733B2
(en)
|
2017-07-21 |
2023-06-13 |
Amgen Inc. |
Gas permeable sealing member for drug container and methods of assembly
|
|
US11484648B2
(en)
|
2017-07-25 |
2022-11-01 |
Amgen Inc. |
Drug delivery device with container access system and related method of assembly
|
|
JP2020528296A
(ja)
|
2017-07-25 |
2020-09-24 |
アムジエン・インコーポレーテツド |
ギヤモジュールを有する薬物送達デバイス及び関連する組立方法
|
|
WO2019032482A2
(en)
|
2017-08-09 |
2019-02-14 |
Amgen Inc. |
HYDRAULIC-PNEUMATIC PRESSURE CHAMBER DELIVERY SYSTEM
|
|
US11103636B2
(en)
|
2017-08-22 |
2021-08-31 |
Amgen Inc. |
Needle insertion mechanism for drug delivery device
|
|
ES2939292T3
(es)
|
2017-10-04 |
2023-04-20 |
Amgen Inc |
Adaptador de flujo para dispositivo de administración de fármacos
|
|
EP4257164A3
(en)
|
2017-10-06 |
2024-01-17 |
Amgen Inc. |
Drug delivery device with interlock assembly and related method of assembly
|
|
EP3694578B1
(en)
|
2017-10-09 |
2025-09-24 |
Amgen Inc. |
Drug delivery device with drive assembly and related method of assembly
|
|
AU2018347521A1
(en)
|
2017-10-12 |
2020-05-07 |
Immunowake Inc. |
VEGFR-antibody light chain fusion protein
|
|
MA50528A
(fr)
|
2017-11-03 |
2020-09-09 |
Amgen Inc |
Systèmes et approches pour stériliser un dispositif d'administration de médicament
|
|
WO2019089178A1
(en)
|
2017-11-06 |
2019-05-09 |
Amgen Inc. |
Drug delivery device with placement and flow sensing
|
|
IL319987A
(en)
|
2017-11-10 |
2025-06-01 |
Amgen Inc |
Plungers for drug delivery devices
|
|
SG11202003004RA
(en)
|
2017-11-16 |
2020-04-29 |
Amgen Inc |
Door latch mechanism for drug delivery device
|
|
CN112105649B
(zh)
|
2018-03-09 |
2025-09-05 |
索伦托药业有限公司 |
二聚体抗原受体(dar)
|
|
KR20200135781A
(ko)
|
2018-03-26 |
2020-12-03 |
암젠 인크 |
세포 배양에서 생산된 항체의 총 비푸코실화 당형태
|
|
US10835685B2
(en)
|
2018-05-30 |
2020-11-17 |
Amgen Inc. |
Thermal spring release mechanism for a drug delivery device
|
|
US11083840B2
(en)
|
2018-06-01 |
2021-08-10 |
Amgen Inc. |
Modular fluid path assemblies for drug delivery devices
|
|
EP3813864A4
(en)
|
2018-06-29 |
2022-07-20 |
Gensun Biopharma Inc. |
Antitumor antagonists
|
|
US12303677B2
(en)
|
2018-07-24 |
2025-05-20 |
Amgen Inc. |
Hybrid drug delivery devices with optional grip portion and related method of preparation
|
|
US12042645B2
(en)
|
2018-07-24 |
2024-07-23 |
Amgen Inc. |
Delivery devices for administering drugs
|
|
US12115360B2
(en)
|
2018-07-24 |
2024-10-15 |
Amgen Inc. |
Hybrid drug delivery devices with grip portion
|
|
MX2021000749A
(es)
|
2018-07-24 |
2021-03-29 |
Amgen Inc |
Dispositivos de suministro para administrar farmacos.
|
|
EP3829692A1
(en)
|
2018-07-31 |
2021-06-09 |
Amgen Inc. |
Fluid path assembly for a drug delivery device
|
|
US20210346601A1
(en)
|
2018-09-24 |
2021-11-11 |
Amgen Inc. |
Interventional dosing systems and methods
|
|
EP3856283A1
(en)
|
2018-09-28 |
2021-08-04 |
Amgen Inc. |
Muscle wire escapement activation assembly for a drug delivery device
|
|
AU2019352616B2
(en)
|
2018-10-02 |
2024-10-10 |
Amgen Inc. |
Injection systems for drug delivery with internal force transmission
|
|
US12151089B2
(en)
|
2018-10-05 |
2024-11-26 |
Amgen Inc. |
Drug delivery device having dose indicator
|
|
JP2022504805A
(ja)
|
2018-10-15 |
2022-01-13 |
アムジエン・インコーポレーテツド |
薬物送達デバイスのプラットフォーム式組み立てプロセス
|
|
SG11202103800RA
(en)
|
2018-10-15 |
2021-05-28 |
Amgen Inc |
Drug delivery device having damping mechanism
|
|
KR102467349B1
(ko)
|
2018-10-29 |
2022-11-16 |
에프. 호프만-라 로슈 아게 |
항체 제형
|
|
TWI831847B
(zh)
|
2018-11-01 |
2024-02-11 |
美商安進公司 |
部分針頭縮回之藥物遞送裝置及其操作方法
|
|
AU2019370159B2
(en)
|
2018-11-01 |
2025-05-29 |
Amgen Inc. |
Drug delivery devices with partial drug delivery member retraction
|
|
US11213620B2
(en)
|
2018-11-01 |
2022-01-04 |
Amgen Inc. |
Drug delivery devices with partial drug delivery member retraction
|
|
SG11202108832XA
(en)
*
|
2019-02-25 |
2021-09-29 |
Pharmabcine Inc |
Anti-ang2 antibody and use thereof
|
|
JP7510952B2
(ja)
|
2019-04-24 |
2024-07-04 |
アムジエン・インコーポレーテツド |
シリンジ滅菌確認アセンブリ及び方法
|
|
WO2020263312A1
(en)
|
2019-06-28 |
2020-12-30 |
Gensun Biopharma, Inc. |
ANTITUMOR ANTAGONIST CONSISTING OF A MUTATED TGFβ1 - RII EXTRACELLULAR DOMAIN AND AN IMMUNOGLOBULIN SCAFFOLD
|
|
EP4013794A4
(en)
*
|
2019-08-12 |
2023-11-22 |
City of Hope |
ANTI-IL1RAP ANTIBODIES
|
|
JP7608439B2
(ja)
|
2019-08-23 |
2025-01-06 |
アムジエン・インコーポレーテツド |
構成可能な針シールド係合構成要素を備えた薬物送達デバイス及び関連方法
|
|
MX2022003461A
(es)
|
2019-09-26 |
2022-04-19 |
Amgen Inc |
Metodos de produccion de composiciones de anticuerpos.
|
|
US11999787B2
(en)
*
|
2020-03-24 |
2024-06-04 |
Genentech, Inc. |
Tie2-binding agents and methods of use
|
|
WO2021247892A1
(en)
|
2020-06-04 |
2021-12-09 |
Amgen Inc. |
Assessment of cleaning procedures of a biotherapeutic manufacturing process
|
|
WO2022028563A1
(en)
*
|
2020-08-07 |
2022-02-10 |
Nanjing GenScript Biotech Co., Ltd. |
Antibodies against human angiopoietin-2 and uses thereof
|
|
WO2022059800A1
(en)
*
|
2020-09-15 |
2022-03-24 |
Santen Pharmaceutical Co., Ltd. |
Bispecific binding molecules against vegf and ang2
|
|
MX2023004364A
(es)
|
2020-10-15 |
2023-05-03 |
Amgen Inc |
Glucanos no emparejados relativos en metodos de produccion de anticuerpos.
|
|
CA3217207A1
(en)
|
2021-05-21 |
2022-11-24 |
Amgen Inc. |
Method of optimizing a filling recipe for a drug container
|
|
US20220389120A1
(en)
|
2021-06-03 |
2022-12-08 |
Gensun Biopharma Inc. |
Multispecific antagonists
|
|
AU2022289365A1
(en)
|
2021-06-07 |
2023-12-14 |
Amgen Inc. |
Using fucosidase to control afucosylation level of glycosylated proteins
|
|
AU2022361382A1
(en)
|
2021-10-05 |
2024-03-28 |
Amgen Inc. |
Fc-gamma receptor ii binding and glycan content
|
|
WO2023215725A1
(en)
|
2022-05-02 |
2023-11-09 |
Fred Hutchinson Cancer Center |
Compositions and methods for cellular immunotherapy
|
|
CN115925904B
(zh)
*
|
2022-08-24 |
2023-06-16 |
南京市第二医院 |
一种新冠病毒单克隆中和抗体及其应用
|
|
CN117820490A
(zh)
*
|
2022-09-28 |
2024-04-05 |
科兴生物制药股份有限公司 |
Vegf和ang-2双特异性抗体及其应用
|
|
AU2024256160A1
(en)
|
2023-04-20 |
2025-10-02 |
Amgen Inc. |
Methods of determining relative unpaired glycan content
|
|
WO2025038600A1
(en)
|
2023-08-14 |
2025-02-20 |
Amgen Inc. |
Methods for reducing yellow color
|
|
WO2025101820A1
(en)
|
2023-11-08 |
2025-05-15 |
Fred Hutchinson Cancer Center |
Compositions and methods for cellular immunotherapy
|
|
WO2026030152A1
(en)
|
2024-07-29 |
2026-02-05 |
Amgen Inc. |
System and method for assessing transferability of a fill recipe
|