JP2018512138A5 - - Google Patents
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- JP2018512138A5 JP2018512138A5 JP2017550931A JP2017550931A JP2018512138A5 JP 2018512138 A5 JP2018512138 A5 JP 2018512138A5 JP 2017550931 A JP2017550931 A JP 2017550931A JP 2017550931 A JP2017550931 A JP 2017550931A JP 2018512138 A5 JP2018512138 A5 JP 2018512138A5
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- tim
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- 239000011230 binding agent Substances 0.000 claims 32
- 125000003275 alpha amino acid group Chemical group 0.000 claims 24
- 239000008194 pharmaceutical composition Substances 0.000 claims 12
- 108010047041 Complementarity Determining Regions Proteins 0.000 claims 9
- 239000012634 fragment Substances 0.000 claims 8
- 108060003951 Immunoglobulin Proteins 0.000 claims 4
- 102000006496 Immunoglobulin Heavy Chains Human genes 0.000 claims 4
- 108010019476 Immunoglobulin Heavy Chains Proteins 0.000 claims 4
- 102000013463 Immunoglobulin Light Chains Human genes 0.000 claims 4
- 108010065825 Immunoglobulin Light Chains Proteins 0.000 claims 4
- 102000015728 Mucins Human genes 0.000 claims 4
- 108010063954 Mucins Proteins 0.000 claims 4
- 210000001744 T-lymphocyte Anatomy 0.000 claims 4
- 201000010099 disease Diseases 0.000 claims 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 4
- 102000018358 immunoglobulin Human genes 0.000 claims 4
- 241000700605 Viruses Species 0.000 claims 3
- 239000000427 antigen Substances 0.000 claims 3
- 102000036639 antigens Human genes 0.000 claims 3
- 108091007433 antigens Proteins 0.000 claims 3
- 208000023275 Autoimmune disease Diseases 0.000 claims 2
- 241000725303 Human immunodeficiency virus Species 0.000 claims 2
- 241000124008 Mammalia Species 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 2
- 241000725643 Respiratory syncytial virus Species 0.000 claims 2
- 201000011510 cancer Diseases 0.000 claims 2
- 208000015181 infectious disease Diseases 0.000 claims 2
- 150000007523 nucleic acids Chemical group 0.000 claims 2
- 201000000596 systemic lupus erythematosus Diseases 0.000 claims 2
- 241000894006 Bacteria Species 0.000 claims 1
- 206010005003 Bladder cancer Diseases 0.000 claims 1
- 206010006187 Breast cancer Diseases 0.000 claims 1
- 208000026310 Breast neoplasm Diseases 0.000 claims 1
- 206010008342 Cervix carcinoma Diseases 0.000 claims 1
- 206010009900 Colitis ulcerative Diseases 0.000 claims 1
- 206010009944 Colon cancer Diseases 0.000 claims 1
- 208000035473 Communicable disease Diseases 0.000 claims 1
- 208000011231 Crohn disease Diseases 0.000 claims 1
- 208000001490 Dengue Diseases 0.000 claims 1
- 206010012310 Dengue fever Diseases 0.000 claims 1
- 208000022072 Gallbladder Neoplasms Diseases 0.000 claims 1
- 102100034458 Hepatitis A virus cellular receptor 2 Human genes 0.000 claims 1
- 241000700721 Hepatitis B virus Species 0.000 claims 1
- 101001068133 Homo sapiens Hepatitis A virus cellular receptor 2 Proteins 0.000 claims 1
- 108010054477 Immunoglobulin Fab Fragments Proteins 0.000 claims 1
- 102000001706 Immunoglobulin Fab Fragments Human genes 0.000 claims 1
- 108010067060 Immunoglobulin Variable Region Proteins 0.000 claims 1
- 102000017727 Immunoglobulin Variable Region Human genes 0.000 claims 1
- 102000017578 LAG3 Human genes 0.000 claims 1
- 101150030213 Lag3 gene Proteins 0.000 claims 1
- 206010023825 Laryngeal cancer Diseases 0.000 claims 1
- 206010058467 Lung neoplasm malignant Diseases 0.000 claims 1
- 208000002030 Merkel cell carcinoma Diseases 0.000 claims 1
- 206010029266 Neuroendocrine carcinoma of the skin Diseases 0.000 claims 1
- 206010061902 Pancreatic neoplasm Diseases 0.000 claims 1
- 102100040678 Programmed cell death protein 1 Human genes 0.000 claims 1
- 101710089372 Programmed cell death protein 1 Proteins 0.000 claims 1
- 206010060862 Prostate cancer Diseases 0.000 claims 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 1
- 201000004681 Psoriasis Diseases 0.000 claims 1
- 208000006265 Renal cell carcinoma Diseases 0.000 claims 1
- 208000004337 Salivary Gland Neoplasms Diseases 0.000 claims 1
- 206010061934 Salivary gland cancer Diseases 0.000 claims 1
- 206010039710 Scleroderma Diseases 0.000 claims 1
- 208000005718 Stomach Neoplasms Diseases 0.000 claims 1
- 208000024770 Thyroid neoplasm Diseases 0.000 claims 1
- 206010067584 Type 1 diabetes mellitus Diseases 0.000 claims 1
- 201000006704 Ulcerative Colitis Diseases 0.000 claims 1
- 208000007097 Urinary Bladder Neoplasms Diseases 0.000 claims 1
- 208000006105 Uterine Cervical Neoplasms Diseases 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 201000010881 cervical cancer Diseases 0.000 claims 1
- 208000029742 colonic neoplasm Diseases 0.000 claims 1
- 208000017763 cutaneous neuroendocrine carcinoma Diseases 0.000 claims 1
- 208000025729 dengue disease Diseases 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 239000012636 effector Substances 0.000 claims 1
- 201000010175 gallbladder cancer Diseases 0.000 claims 1
- 206010017758 gastric cancer Diseases 0.000 claims 1
- 230000005764 inhibitory process Effects 0.000 claims 1
- 206010023841 laryngeal neoplasm Diseases 0.000 claims 1
- 201000007270 liver cancer Diseases 0.000 claims 1
- 208000014018 liver neoplasm Diseases 0.000 claims 1
- 201000005202 lung cancer Diseases 0.000 claims 1
- 208000020816 lung neoplasm Diseases 0.000 claims 1
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 claims 1
- 201000001441 melanoma Diseases 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 201000006417 multiple sclerosis Diseases 0.000 claims 1
- 201000002528 pancreatic cancer Diseases 0.000 claims 1
- 208000008443 pancreatic carcinoma Diseases 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 208000015347 renal cell adenocarcinoma Diseases 0.000 claims 1
- 206010039073 rheumatoid arthritis Diseases 0.000 claims 1
- 201000011549 stomach cancer Diseases 0.000 claims 1
- 201000002510 thyroid cancer Diseases 0.000 claims 1
- 241000712461 unidentified influenza virus Species 0.000 claims 1
- 201000005112 urinary bladder cancer Diseases 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562141353P | 2015-04-01 | 2015-04-01 | |
| US62/141,353 | 2015-04-01 | ||
| PCT/US2016/025532 WO2016161270A1 (en) | 2015-04-01 | 2016-04-01 | Antibodies directed against t cell immunoglobulin and mucin protein 3 (tim-3) |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2018512138A JP2018512138A (ja) | 2018-05-17 |
| JP2018512138A5 true JP2018512138A5 (enExample) | 2019-05-16 |
| JP6949717B2 JP6949717B2 (ja) | 2021-10-13 |
Family
ID=57007695
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017550931A Active JP6949717B2 (ja) | 2015-04-01 | 2016-04-01 | Ｔ細胞免疫グロブリン及びムチンタンパク質３（ｔｉｍ−３）に対する抗体 |
Country Status (24)
| Country | Link |
|---|---|
| US (3) | US10508149B2 (enExample) |
| EP (2) | EP4442712A3 (enExample) |
| JP (1) | JP6949717B2 (enExample) |
| KR (1) | KR102711906B1 (enExample) |
| CN (2) | CN107847589B (enExample) |
| AU (1) | AU2016242964C1 (enExample) |
| DK (1) | DK3277321T3 (enExample) |
| EA (1) | EA201792184A1 (enExample) |
| ES (1) | ES2988351T3 (enExample) |
| FI (1) | FI3277321T3 (enExample) |
| HR (1) | HRP20241498T1 (enExample) |
| HU (1) | HUE068448T2 (enExample) |
| IL (2) | IL283006B2 (enExample) |
| LT (1) | LT3277321T (enExample) |
| MA (1) | MA41867B1 (enExample) |
| MX (1) | MX383216B (enExample) |
| PL (1) | PL3277321T3 (enExample) |
| PT (1) | PT3277321T (enExample) |
| RS (1) | RS66030B1 (enExample) |
| SG (2) | SG10201909173PA (enExample) |
| SI (1) | SI3277321T1 (enExample) |
| SM (1) | SMT202400420T1 (enExample) |
| WO (1) | WO2016161270A1 (enExample) |
| ZA (1) | ZA201706740B (enExample) |
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