JP2019512207A5 - - Google Patents
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- JP2019512207A5 JP2019512207A5 JP2018536458A JP2018536458A JP2019512207A5 JP 2019512207 A5 JP2019512207 A5 JP 2019512207A5 JP 2018536458 A JP2018536458 A JP 2018536458A JP 2018536458 A JP2018536458 A JP 2018536458A JP 2019512207 A5 JP2019512207 A5 JP 2019512207A5
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- JP
- Japan
- Prior art keywords
- amino acid
- acid sequence
- variable region
- chain variable
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662278815P | 2016-01-14 | 2016-01-14 | |
| US62/278,815 | 2016-01-14 | ||
| PCT/US2017/013511 WO2017124001A2 (en) | 2016-01-14 | 2017-01-13 | T cell receptor-like antibodies specific for foxp3-derived peptides |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019512207A JP2019512207A (ja) | 2019-05-16 |
| JP2019512207A5 true JP2019512207A5 (enExample) | 2020-02-20 |
| JP7022067B2 JP7022067B2 (ja) | 2022-02-17 |
Family
ID=59311684
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018536458A Expired - Fee Related JP7022067B2 (ja) | 2016-01-14 | 2017-01-13 | Foxp3由来のペプチドに特異的なt細胞受容体様抗体 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US11505599B2 (enExample) |
| EP (1) | EP3402518A4 (enExample) |
| JP (1) | JP7022067B2 (enExample) |
| CN (1) | CN109069627A (enExample) |
| WO (1) | WO2017124001A2 (enExample) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6974311B2 (ja) * | 2015-06-23 | 2021-12-01 | メモリアル スローン ケタリング キャンサー センター | 新規pd−1免疫調節剤 |
| MX2018004721A (es) | 2015-10-23 | 2018-07-06 | Eureka Therapeutics Inc | Construcciones quimericas anticuerpo/receptor de celulas t y usos de las mismas. |
| WO2018200582A1 (en) | 2017-04-26 | 2018-11-01 | Eureka Therapeutics, Inc. | Chimeric antibody/t-cell receptor constructs and uses thereof |
| MX2020001879A (es) * | 2017-08-18 | 2020-07-29 | Gritstone Oncology Inc | Proteínas de fijación al antígeno que se dirigen a antígenos compartidos. |
| CN112041432A (zh) * | 2018-02-15 | 2020-12-04 | 纪念斯隆-凯特林癌症中心 | Foxp3靶向剂组合物以及用于过继细胞疗法的使用方法 |
| CN113603783B (zh) * | 2018-12-21 | 2022-07-12 | 浙江时迈药业有限公司 | 蛋白酶可切割的双特异性抗体及其用途 |
| WO2022082030A2 (en) | 2020-10-15 | 2022-04-21 | Gritstone Bio, Inc. | Antigen-binding proteins and related methods of use |
| WO2022155503A1 (en) | 2021-01-14 | 2022-07-21 | Gritstone Bio, Inc. | Multi-specific antibodies and methods of use |
| WO2022165419A1 (en) | 2021-02-01 | 2022-08-04 | Kyverna Therapeutics, Inc. | Methods for increasing t-cell function |
| US20230056336A1 (en) * | 2021-04-15 | 2023-02-23 | Kyverna Therapeutics, Inc. | Methods and compositions for treating disease using targeted foxp3+cd4+ t cells and cellular suicide agents |
| WO2024100170A1 (en) | 2022-11-11 | 2024-05-16 | F. Hoffmann-La Roche Ag | Antibodies binding to hla-a*02/foxp3 |
| US20260226173A1 (en) * | 2023-02-06 | 2026-08-06 | Memorial Sloan-Kettering Cancer Center | Compositions including anti-wt-1 antibodies & antigen binding fragments and uses thereof |
| WO2025145063A1 (en) * | 2023-12-29 | 2025-07-03 | Eureka Therapeutics, Inc. | Constructs targeting msln peptide/mhc complexes and uses thereof |
| WO2025149667A1 (en) | 2024-01-12 | 2025-07-17 | Pheon Therapeutics Ltd | Antibody drug conjugates and uses thereof |
| CN122187960B (zh) * | 2026-05-15 | 2026-08-07 | 四川大学华西医院 | 一种针对呼吸道合胞病毒的强效中和抗体rsv-34及其应用 |
Family Cites Families (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1975A (en) | 1841-02-12 | Manner of constructing corn-shellers | ||
| DE3572982D1 (en) | 1984-03-06 | 1989-10-19 | Takeda Chemical Industries Ltd | Chemically modified lymphokine and production thereof |
| US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
| US5091513A (en) | 1987-05-21 | 1992-02-25 | Creative Biomolecules, Inc. | Biosynthetic antibody binding sites |
| US5132405A (en) | 1987-05-21 | 1992-07-21 | Creative Biomolecules, Inc. | Biosynthetic antibody binding sites |
| JPS6412935A (en) | 1987-07-02 | 1989-01-17 | Mitsubishi Electric Corp | Constant-speed travel device for vehicle |
| US5677425A (en) | 1987-09-04 | 1997-10-14 | Celltech Therapeutics Limited | Recombinant antibody |
| EP0401384B1 (en) | 1988-12-22 | 1996-03-13 | Kirin-Amgen, Inc. | Chemically modified granulocyte colony stimulating factor |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US5714350A (en) | 1992-03-09 | 1998-02-03 | Protein Design Labs, Inc. | Increasing antibody affinity by altering glycosylation in the immunoglobulin variable region |
| AU4116793A (en) | 1992-04-24 | 1993-11-29 | Board Of Regents, The University Of Texas System | Recombinant production of immunoglobulin-like domains in prokaryotic cells |
| US5869046A (en) | 1995-04-14 | 1999-02-09 | Genentech, Inc. | Altered polypeptides with increased half-life |
| US6121022A (en) | 1995-04-14 | 2000-09-19 | Genentech, Inc. | Altered polypeptides with increased half-life |
| EP0983303B1 (en) | 1997-05-21 | 2006-03-08 | Biovation Limited | Method for the production of non-immunogenic proteins |
| HUP0104865A3 (en) | 1999-01-15 | 2004-07-28 | Genentech Inc | Polypeptide variants with altered effector function |
| US6436703B1 (en) | 2000-03-31 | 2002-08-20 | Hyseq, Inc. | Nucleic acids and polypeptides |
| US20030059427A1 (en) * | 2000-04-28 | 2003-03-27 | Force Walker R. | Isolation and characterization of highly active anti-CD40 antibody |
| CA2658221C (en) * | 2001-04-27 | 2012-11-27 | Kyowa Kirin Co., Ltd. | Anti-cd40 monoclonal antibody |
| US20100003253A1 (en) * | 2002-11-08 | 2010-01-07 | Ablynx N.V. | Single domain antibodies directed against epidermal growth factor receptor and uses therefor |
| NZ540194A (en) | 2002-11-08 | 2008-07-31 | Ablynx Nv | Single domain antibodies directed against tumour necrosis factor-alpha and uses therefor |
| US9320792B2 (en) | 2002-11-08 | 2016-04-26 | Ablynx N.V. | Pulmonary administration of immunoglobulin single variable domains and constructs thereof |
| PL2314621T3 (pl) | 2004-05-27 | 2014-08-29 | Crucell Holland Bv | Cząsteczki wiążące zdolne do neutralizowania wirusa wścieklizny i ich zastosowania |
| JP4829609B2 (ja) | 2004-12-22 | 2011-12-07 | 独立行政法人科学技術振興機構 | ヒト抗体酵素およびその生産方法 |
| EP1937814A4 (en) | 2005-09-01 | 2010-05-05 | Ca Nat Research Council | ANTIAPOPTOTIC PROTEIN ANTIBODY |
| WO2008066784A2 (en) * | 2006-11-27 | 2008-06-05 | Ludwig Institute For Cancer Research | Expression of foxp3 by cancer cells |
| TWI441648B (zh) * | 2007-01-03 | 2014-06-21 | Oncotherapy Science Inc | Foxp3胜肽疫苗 |
| WO2009003489A1 (en) * | 2007-07-02 | 2009-01-08 | Natimmune A/S | CaOU-1 EPITOPE BINDING POLYPEPTIDES |
| EP2020419A1 (en) * | 2007-07-31 | 2009-02-04 | Bayer Schering Pharma Aktiengesellschaft | Anti ephB4 antibody fragments |
| EP3524619A1 (en) | 2007-12-06 | 2019-08-14 | Dana-Farber Cancer Institute, Inc. | Antibodies against influenza virus and methods of use thereof |
| EP2246426A4 (en) * | 2008-01-29 | 2011-08-10 | Inst Antibodies Co Ltd | COMPOSITION FOR THE NEUTRALIZATION OF BOTULINUS TOXIN TYPE-A AND HUMAN ANTIBODIES AGAINST BOTULINUS TOXIN TYPE-A |
| BRPI0911501A2 (pt) * | 2008-04-29 | 2015-07-28 | Monsanto Technology Llc | Genes e usos para melhoramento de plantas. |
| US20120005773A1 (en) * | 2008-10-01 | 2012-01-05 | Aasen Eric D | Transgenic plants with enhanced agronomic traits |
| US9221902B2 (en) * | 2008-11-07 | 2015-12-29 | Fabrus, Inc. | Combinatorial antibody libraries and uses thereof |
| WO2010099083A1 (en) * | 2009-02-27 | 2010-09-02 | Monsanto Technology Llc | Isolated novel nucleic acid and protein molecules from soybeans and methods of using those molecules |
| JP6012473B2 (ja) | 2010-01-11 | 2016-10-25 | アレクシオン ファーマシューティカルズ, インコーポレイテッド | 抗cd200抗体を用いたヒトの処置における免疫調節効果のバイオマーカー |
| PH12013501201A1 (en) * | 2010-12-09 | 2013-07-29 | Univ Pennsylvania | Use of chimeric antigen receptor-modified t cells to treat cancer |
| SG191977A1 (en) * | 2011-02-01 | 2013-08-30 | Genmab As | Human antibodies and antibody-drug conjugates against cd74 |
| WO2015070061A1 (en) * | 2013-11-07 | 2015-05-14 | Memorial Sloan-Kettering Cancer Center | Anti-wt1/hla bi-specific antibody |
| US20130102031A1 (en) * | 2011-10-25 | 2013-04-25 | Anaptysbio, Inc. | Use of somatic hypermutation to create insertion and deletion mutations in vitro |
| US9175082B2 (en) * | 2012-05-31 | 2015-11-03 | Sorrento Therapeutics, Inc. | Antigen binding proteins that bind PD-L1 |
| WO2014036562A2 (en) * | 2012-08-31 | 2014-03-06 | University Of Virginia Patent Foundation | Target peptides for immunotherapy and diagnostics |
| US10273301B2 (en) | 2013-12-24 | 2019-04-30 | Janssen Pharmaceutica Nv | Anti-vista antibodies and fragments |
| GB201410520D0 (en) | 2014-06-12 | 2014-07-30 | Univ London Queen Mary | Antibody |
-
2017
- 2017-01-13 US US16/069,999 patent/US11505599B2/en active Active
- 2017-01-13 CN CN201780017192.9A patent/CN109069627A/zh active Pending
- 2017-01-13 EP EP17739080.4A patent/EP3402518A4/en not_active Withdrawn
- 2017-01-13 WO PCT/US2017/013511 patent/WO2017124001A2/en not_active Ceased
- 2017-01-13 JP JP2018536458A patent/JP7022067B2/ja not_active Expired - Fee Related
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