JP2013502204A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2013502204A5 JP2013502204A5 JP2012525000A JP2012525000A JP2013502204A5 JP 2013502204 A5 JP2013502204 A5 JP 2013502204A5 JP 2012525000 A JP2012525000 A JP 2012525000A JP 2012525000 A JP2012525000 A JP 2012525000A JP 2013502204 A5 JP2013502204 A5 JP 2013502204A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- sequence
- cdr3
- cdr1
- cdr2
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000427 antigen Substances 0.000 claims 11
- 102000036639 antigens Human genes 0.000 claims 11
- 108091007433 antigens Proteins 0.000 claims 11
- 102000005962 receptors Human genes 0.000 claims 10
- 108020003175 receptors Proteins 0.000 claims 10
- 108010047041 Complementarity Determining Regions Proteins 0.000 claims 7
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 201000011510 cancer Diseases 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2009903928 | 2009-08-20 | ||
| AU2009903928A AU2009903928A0 (en) | 2009-08-20 | Anti P2X7 receptor antibodies and fragments thereof | |
| PCT/AU2010/001070 WO2011020155A1 (en) | 2009-08-20 | 2010-08-20 | Anti p2x7 receptor antibodies and fragments thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016019816A Division JP6224141B2 (ja) | 2009-08-20 | 2016-02-04 | 抗ｐ２ｘ７受容体抗体およびその断片 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013502204A JP2013502204A (ja) | 2013-01-24 |
| JP2013502204A5 true JP2013502204A5 (enExample) | 2013-10-03 |
| JP5936067B2 JP5936067B2 (ja) | 2016-06-15 |
Family
ID=43606479
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012525000A Active JP5936067B2 (ja) | 2009-08-20 | 2010-08-20 | 抗ｐ２ｘ７受容体抗体およびその断片 |
| JP2016019816A Active JP6224141B2 (ja) | 2009-08-20 | 2016-02-04 | 抗ｐ２ｘ７受容体抗体およびその断片 |
| JP2017193317A Active JP6417016B2 (ja) | 2009-08-20 | 2017-10-03 | 抗ｐ２ｘ７受容体抗体およびその断片 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016019816A Active JP6224141B2 (ja) | 2009-08-20 | 2016-02-04 | 抗ｐ２ｘ７受容体抗体およびその断片 |
| JP2017193317A Active JP6417016B2 (ja) | 2009-08-20 | 2017-10-03 | 抗ｐ２ｘ７受容体抗体およびその断片 |
Country Status (5)
| Country | Link |
|---|---|
| US (6) | US9127059B2 (enExample) |
| EP (3) | EP3395832B1 (enExample) |
| JP (3) | JP5936067B2 (enExample) |
| ES (3) | ES2704711T3 (enExample) |
| WO (1) | WO2011020155A1 (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101555283B (zh) | 2001-01-17 | 2012-03-21 | 生物权威国际有限公司 | 针对非功能性p2x7受体的抗体及其在癌症和其它病情的诊断和治疗中的用途 |
| JP5670192B2 (ja) | 2007-09-14 | 2015-02-18 | バイオセプター・インターナショナル・リミテッド | 新規ｐ２ｘ７エピトープ |
| WO2009033234A1 (en) | 2007-09-14 | 2009-03-19 | Biosceptre International Limited | Purinergic (p2x) receptors in extra-cellular body fluid |
| AU2009266430B2 (en) | 2008-07-04 | 2014-08-14 | Biosceptre International Limited | Anti- P2X7 peptides and epitopes |
| EP3395832B1 (en) | 2009-08-20 | 2021-11-24 | Biosceptre (Aust) Pty Ltd | Anti p2x7 receptor antibodies and fragments thereof |
| EP2516470B1 (en) | 2009-12-24 | 2018-02-07 | Biosceptre (Aust) Pty Ltd | Antibodies to non-functional oligomeric p2x7 receptors |
| WO2012031333A1 (en) | 2010-09-10 | 2012-03-15 | Biosceptre International Limited | Companion animal treatments |
| WO2013003895A1 (en) | 2011-07-01 | 2013-01-10 | Biosceptre International Limited | Combination therapy |
| CN107614528A (zh) * | 2015-04-02 | 2018-01-19 | 生物权威（英国）有限公司 | 疼痛治疗 |
| US12121539B2 (en) * | 2015-09-11 | 2024-10-22 | Biosceptre (Aust) Pty Ltd | Chimeric antigen receptors and uses thereof |
| GB201522541D0 (en) * | 2015-12-21 | 2016-02-03 | Inst Research In Biomedicine | Compositions |
| CN109862883A (zh) * | 2016-10-21 | 2019-06-07 | 生物权威（英国）有限公司 | 细胞毒性颗粒 |
| AU2019275479B2 (en) | 2018-05-21 | 2022-12-08 | Biosceptre (Aust) Pty Ltd | Chimeric antigen receptors with modified linker domains and uses thereof |
| FR3084365B1 (fr) * | 2018-07-27 | 2020-10-23 | Cisbio Bioassays | Anticorps a domaine unique qui se lient a la proteine g alpha |
| EP3890773A4 (en) * | 2018-11-08 | 2022-11-09 | Orionis Biosciences, Inc. | MODULATION OF DENDRITIC CELL LINES |
| CN110054691B (zh) * | 2019-05-09 | 2021-09-07 | 潍坊医学院 | 一种抗人p2rx7单克隆抗体的杂交瘤细胞系 |
| JP7853205B2 (ja) * | 2019-07-26 | 2026-04-28 | バイオセプター （オースト） プロプライエタリー・リミテッド | Ｐ２ｘ７受容体の標的療法 |
| CN111234016B (zh) * | 2020-02-23 | 2021-09-07 | 北京康普美特创新医药科技有限责任公司 | 一种抗补体c5分子的全人源单克隆抗体及应用 |
| CN111171149B (zh) * | 2020-02-23 | 2021-09-07 | 北京康普美特创新医药科技有限责任公司 | 一种抗补体c5分子的人源化单链抗体及其应用 |
| CA3211323A1 (en) * | 2021-03-11 | 2022-09-15 | Patrick Schlegel | Novel cell therapy system |
| JP2024532482A (ja) * | 2021-09-01 | 2024-09-05 | バイオセプター （オースト） プロプライエタリー・リミテッド | 免疫活性を刺激するための方法および組成物 |
| WO2025042968A1 (en) * | 2023-08-22 | 2025-02-27 | Integral Molecular, Inc. | Compositions and methods related to chicken recombinant heavy-chain only antibodies |
| WO2026039785A1 (en) * | 2024-08-15 | 2026-02-19 | Integral Molecular, Inc. | Antibodies and compositions against p2x receptors and uses thereof |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0486526B2 (en) | 1989-08-07 | 2001-03-07 | Peptech Limited | Tumour necrosis factor binding ligands |
| IE920765A1 (en) | 1991-03-12 | 1992-09-23 | Scripps Research Inst | Cell surface receptors homologous to coagulation factors v¹and viii |
| EP0760850A1 (en) | 1994-05-27 | 1997-03-12 | Glaxo Group Limited | P2x RECEPTORS (PURINOCEPTOR FAMILY) |
| US5981218A (en) | 1995-08-09 | 1999-11-09 | Bristol-Myers Squibb Company | Isolated nucleic acid molecules useful as leukemia markers and in breast cancer prognosis and encoded polypeptides |
| JP2001521372A (ja) | 1996-04-30 | 2001-11-06 | スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー | ヒトＰ２ｘ４レセプタースプライス−変異体 |
| US6303338B1 (en) | 1996-08-16 | 2001-10-16 | Human Genome Sciences, Inc. | Pancreas-derived plasminogen activator inhibitor |
| US6306393B1 (en) | 1997-03-24 | 2001-10-23 | Immunomedics, Inc. | Immunotherapy of B-cell malignancies using anti-CD22 antibodies |
| JP3885177B2 (ja) | 1997-03-26 | 2007-02-21 | 大塚製薬株式会社 | ヒト遺伝子 |
| US6133434A (en) | 1997-04-28 | 2000-10-17 | Glaxo Group Limited | Purinergic receptor |
| DE69941187D1 (de) | 1998-06-01 | 2009-09-10 | Agensys Inc | Serpentintransmembranantigene exprimiert in menschlichem krebs und deren verwendungen |
| DE19829473C2 (de) | 1998-07-01 | 2000-08-10 | Magnus Von Knebel Doeberitz Ch | Verfahren zur frühen Diagnose von Carcinomen |
| EP1157038A4 (en) | 1999-02-26 | 2005-01-19 | Smithkline Beecham Corp | CLONING OF A P2Y-LIKE 7TM RECEPTOR (AXOR17) |
| AUPP991199A0 (en) | 1999-04-21 | 1999-05-13 | University Of Sydney, The | Methods for diagnosing pre-cancerous and cancerous conditions |
| WO2001030964A2 (en) | 1999-10-22 | 2001-05-03 | Lifespan Biosciences, Inc. | Anti-cancer nucleic acid and protein targets |
| AUPR201500A0 (en) | 2000-12-11 | 2001-01-11 | Biosceptre Pty Ltd | Methods for identifying pre-neoplastic and neoplastic states in mammals |
| WO2003020762A1 (en) | 2001-09-03 | 2003-03-13 | Intreat Pty Limited | Antibodies to non-functional p2x7receptor, diagnosis and treatment of cancers and other conditions |
| CN101555283B (zh) | 2001-01-17 | 2012-03-21 | 生物权威国际有限公司 | 针对非功能性p2x7受体的抗体及其在癌症和其它病情的诊断和治疗中的用途 |
| IL159177A0 (en) * | 2001-06-20 | 2004-06-01 | Prochon Biotech Ltd | Antibodies that block receptor protein tyrosine kinase activation, methods of screening for and uses thereof |
| PL1469072T3 (pl) | 2003-04-17 | 2008-03-31 | Affectis Pharmaceuticals Ag | Środki i sposoby diagnozowania i leczenia chorób afektywnych |
| US7371825B2 (en) * | 2004-06-30 | 2008-05-13 | Centocor, Inc. | Anti-MCP-1 antibodies, compositions, methods and uses |
| CA2575791A1 (en) * | 2004-08-03 | 2006-02-16 | Dyax Corp. | Hk1-binding proteins |
| US20090215727A1 (en) | 2005-05-05 | 2009-08-27 | Medicure International Inc. | Inhibition of atp-mediated, p2x7 dependent pathways by pyridoxal-5-phosphate and vitamin b6 related compounds |
| US7767789B2 (en) | 2005-06-02 | 2010-08-03 | University Hopitals of Cleveland | Truncated proteins as cancer markers |
| US20100088778A1 (en) * | 2005-06-16 | 2010-04-08 | John Charles Mulley | Methods of Treatment, and Diagnosis of Epilepsy by Detecting Mutations in the SCN1A Gene |
| WO2007027957A2 (en) | 2005-08-31 | 2007-03-08 | Cell Signaling Technology, Inc. | Reagents for the detection of protein phosphorylation in leukemia signaling pathways |
| US20070207152A1 (en) * | 2005-11-09 | 2007-09-06 | Brophy Susan E | Human BNP immunospecific antibodies |
| WO2008043145A1 (en) | 2006-10-10 | 2008-04-17 | Biosceptre International Limited | Hybridomas producing antibodies against non functional p2x7 receptor |
| US20100036101A1 (en) | 2006-10-10 | 2010-02-11 | Angus Gidley-Baird | Antibodies against non functional p2x7 receptor |
| JP5670192B2 (ja) * | 2007-09-14 | 2015-02-18 | バイオセプター・インターナショナル・リミテッド | 新規ｐ２ｘ７エピトープ |
| WO2009033234A1 (en) | 2007-09-14 | 2009-03-19 | Biosceptre International Limited | Purinergic (p2x) receptors in extra-cellular body fluid |
| AU2009266430B2 (en) | 2008-07-04 | 2014-08-14 | Biosceptre International Limited | Anti- P2X7 peptides and epitopes |
| EP3395832B1 (en) | 2009-08-20 | 2021-11-24 | Biosceptre (Aust) Pty Ltd | Anti p2x7 receptor antibodies and fragments thereof |
| EP2516470B1 (en) | 2009-12-24 | 2018-02-07 | Biosceptre (Aust) Pty Ltd | Antibodies to non-functional oligomeric p2x7 receptors |
| WO2011131472A1 (en) | 2010-04-22 | 2011-10-27 | Institut Gustave Roussy | Compounds and uses thereof to induce an immunogenic cancer cell death in a subject |
| WO2012031333A1 (en) | 2010-09-10 | 2012-03-15 | Biosceptre International Limited | Companion animal treatments |
| WO2013003895A1 (en) | 2011-07-01 | 2013-01-10 | Biosceptre International Limited | Combination therapy |
-
2010
- 2010-08-20 EP EP18175591.9A patent/EP3395832B1/en active Active
- 2010-08-20 WO PCT/AU2010/001070 patent/WO2011020155A1/en not_active Ceased
- 2010-08-20 ES ES15178381T patent/ES2704711T3/es active Active
- 2010-08-20 JP JP2012525000A patent/JP5936067B2/ja active Active
- 2010-08-20 US US13/391,619 patent/US9127059B2/en active Active
- 2010-08-20 EP EP10809371.7A patent/EP2467404B1/en active Active
- 2010-08-20 ES ES10809371.7T patent/ES2557456T3/es active Active
- 2010-08-20 EP EP15178381.8A patent/EP2966090B1/en active Active
- 2010-08-20 ES ES18175591T patent/ES2904911T3/es active Active
-
2015
- 2015-03-27 US US14/671,254 patent/US9688771B2/en active Active
-
2016
- 2016-02-04 JP JP2016019816A patent/JP6224141B2/ja active Active
-
2017
- 2017-05-18 US US15/599,396 patent/US10053508B2/en active Active
- 2017-10-03 JP JP2017193317A patent/JP6417016B2/ja active Active
-
2018
- 2018-07-11 US US16/032,973 patent/US10988532B2/en active Active
-
2021
- 2021-03-10 US US17/198,179 patent/US12129295B2/en active Active
-
2024
- 2024-09-24 US US18/895,282 patent/US20250084161A1/en active Pending