|
US7608693B2
(en)
|
2006-10-02 |
2009-10-27 |
Regeneron Pharmaceuticals, Inc. |
High affinity human antibodies to human IL-4 receptor
|
|
RU2605390C2
(ru)
|
2011-08-23 |
2016-12-20 |
Рош Гликарт Аг |
Биспецифические антитела, специфичные к антигенам, активирующим т-клетки, и опухолевому антигену, и способы их применения
|
|
TWI679212B
(zh)
|
2011-11-15 |
2019-12-11 |
美商安進股份有限公司 |
針對bcma之e3以及cd3的結合分子
|
|
MX2015003616A
(es)
|
2012-10-08 |
2015-06-05 |
Roche Glycart Ag |
Anticuerpos sin fc que comprenden dos fragmentos fab y metodos de uso.
|
|
CN104968682A
(zh)
|
2013-02-05 |
2015-10-07 |
英格玛布股份公司 |
针对CD3ε和BCMA的双特异性抗体
|
|
MX375359B
(es)
|
2013-02-26 |
2025-03-06 |
Roche Glycart Ag |
Moléculas biespecíficas de unión a antígeno activadoras de células t.
|
|
TWI755763B
(zh)
|
2013-06-04 |
2022-02-21 |
美商再生元醫藥公司 |
藉由投與il-4r抑制劑以治療過敏及增強過敏原-特異之免疫療法的方法
|
|
TWI682781B
(zh)
|
2013-07-11 |
2020-01-21 |
美商再生元醫藥公司 |
藉由投與il-4r抑制劑治療嗜酸性食道炎的方法
|
|
GB201317928D0
(en)
*
|
2013-10-10 |
2013-11-27 |
Ucl Business Plc |
Molecule
|
|
AU2015213437B2
(en)
*
|
2014-02-07 |
2018-04-05 |
Mcmaster University |
Trifunctional T cell-antigen coupler and methods and uses thereof
|
|
US10370449B2
(en)
|
2014-02-28 |
2019-08-06 |
Regeneron Pharmaceuticals, Inc. |
Methods for treating skin infection by administering an IL-4R antagonist
|
|
JP6464255B2
(ja)
|
2014-08-04 |
2019-02-06 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
二重特異性t細胞活性化抗原結合分子
|
|
CA2963692A1
(en)
|
2014-10-09 |
2016-04-14 |
Engmab Ag |
Bispecific antibodies against cd3epsilon and ror1
|
|
EP3023437A1
(en)
*
|
2014-11-20 |
2016-05-25 |
EngMab AG |
Bispecific antibodies against CD3epsilon and BCMA
|
|
HRP20201156T1
(hr)
|
2014-11-20 |
2020-11-13 |
F. Hoffmann - La Roche Ag |
Zajednički laki lanci i postupci primjene
|
|
CA2960929A1
(en)
|
2014-11-20 |
2016-05-26 |
F. Hoffmann-La Roche Ag |
T cell activating bispecific antigen binding molecules against folr1 and cd3
|
|
SG11201704056XA
(en)
|
2014-11-20 |
2017-06-29 |
Hoffmann La Roche |
Combination therapy of t cell activating bispecific antigen binding molecules cd3 abd folate receptor 1 (folr1) and pd-1 axis binding antagonists
|
|
EP3029068A1
(en)
*
|
2014-12-03 |
2016-06-08 |
EngMab AG |
Bispecific antibodies against CD3epsilon and BCMA for use in the treatment of diseases
|
|
TWI703159B
(zh)
|
2015-04-13 |
2020-09-01 |
美商輝瑞股份有限公司 |
Bcma特異性治療性抗體及其用途
|
|
ES3039918T3
(en)
|
2015-04-13 |
2025-10-27 |
Pfizer |
Chimeric antigen receptors targeting b-cell maturation antigen
|
|
KR20180029201A
(ko)
|
2015-05-18 |
2018-03-20 |
티씨알2 테라퓨틱스 인크. |
융합 단백질을 이용하는 tcr 리프로그래밍을 위한 조성물 및 방법
|
|
TWI744242B
(zh)
|
2015-07-31 |
2021-11-01 |
德商安美基研究(慕尼黑)公司 |
Egfrviii及cd3抗體構築體
|
|
TWI829617B
(zh)
|
2015-07-31 |
2024-01-21 |
德商安美基研究(慕尼黑)公司 |
Flt3及cd3抗體構築體
|
|
TWI796283B
(zh)
|
2015-07-31 |
2023-03-21 |
德商安美基研究(慕尼黑)公司 |
Msln及cd3抗體構築體
|
|
EA039859B1
(ru)
|
2015-07-31 |
2022-03-21 |
Эмджен Рисерч (Мюник) Гмбх |
Биспецифические конструкты антител, связывающие egfrviii и cd3
|
|
CN108350073B
(zh)
|
2015-08-03 |
2022-03-18 |
英格玛布有限责任公司 |
针对bcma的单克隆抗体
|
|
CN105384825B
(zh)
*
|
2015-08-11 |
2018-06-01 |
南京传奇生物科技有限公司 |
一种基于单域抗体的双特异性嵌合抗原受体及其应用
|
|
IL320478A
(en)
|
2015-08-17 |
2025-06-01 |
Janssen Biotech Inc |
Anti-BCMA antibodies, bispecific antigen-binding molecules that bind BCMA and CD3, and uses thereof
|
|
AR106188A1
(es)
|
2015-10-01 |
2017-12-20 |
Hoffmann La Roche |
Anticuerpos anti-cd19 humano humanizados y métodos de utilización
|
|
CA2990755A1
(en)
|
2015-10-02 |
2017-04-06 |
F. Hoffman-La Roche Ag |
Bispecific anti-ceaxcd3 t cell activating antigen binding molecules
|
|
CA2997406C
(en)
|
2015-12-09 |
2024-05-28 |
F. Hoffmann-La Roche Ag |
Type ii anti-cd20 antibody for reducing formation of anti-drug antibodies or cytokine release
|
|
CN108368179B
(zh)
|
2016-01-08 |
2022-08-23 |
豪夫迈·罗氏有限公司 |
使用pd-1轴结合拮抗剂和抗cea/抗cd3双特异性抗体治疗cea阳性癌症的方法
|
|
WO2017134158A1
(en)
|
2016-02-03 |
2017-08-10 |
Amgen Research (Munich) Gmbh |
Psma and cd3 bispecific t cell engaging antibody constructs
|
|
KR102688969B1
(ko)
*
|
2016-02-03 |
2024-07-30 |
암젠 리서치 (뮌헨) 게엠베하 |
Bcma 및 cd3 이중특이성 t 세포 맞물림 항체 작제물
|
|
US20170233484A1
(en)
|
2016-02-17 |
2017-08-17 |
Seattle Genetics, Inc. |
Bcma antibodies and use of same to treat cancer and immunological disorders
|
|
AU2017225733A1
(en)
|
2016-03-04 |
2018-09-27 |
Novartis Ag |
Cells expressing multiple chimeric antigen receptor (CAR) molecules and uses therefore
|
|
RS64266B1
(sr)
|
2016-03-22 |
2023-07-31 |
Hoffmann La Roche |
Bispecifični molekul koji aktivira t ćeliju koji se aktivira proteazom
|
|
SG11201808411RA
(en)
|
2016-04-01 |
2018-10-30 |
Kite Pharma Inc |
Chimeric antigen and t cell receptors and methods of use
|
|
CN117903307A
(zh)
*
|
2016-04-01 |
2024-04-19 |
凯德药业股份有限公司 |
Bcma结合分子及其使用方法
|
|
KR20210089262A
(ko)
|
2016-04-01 |
2021-07-15 |
카이트 파마 인코포레이티드 |
키메라 수용체 및 그의 사용 방법
|
|
MX2018012615A
(es)
|
2016-04-15 |
2019-05-30 |
Novartis Ag |
Composiciones y metodos para la expresion selectiva de proteinas.
|
|
KR20230129583A
(ko)
*
|
2016-06-21 |
2023-09-08 |
테네오바이오, 인코포레이티드 |
Cd3 결합 항체
|
|
RU2019105693A
(ru)
|
2016-08-01 |
2020-09-01 |
Новартис Аг |
Лечение рака с применением химерного антигенного рецептора в комбинации с ингибитором молекулы, способствующей фенотипу m2 макрофага
|
|
EP3494138A1
(en)
|
2016-08-02 |
2019-06-12 |
TCR2 Therapeutics Inc. |
Compositions and methods for tcr reprogramming using fusion proteins
|
|
HUE067888T2
(hu)
|
2016-09-01 |
2024-11-28 |
Regeneron Pharma |
Módszerek az allergia megelõzésére vagy kezelésére egy IL-4R antagonista adagolásával
|
|
US20180064758A1
(en)
*
|
2016-09-05 |
2018-03-08 |
Ucl Business Plc |
Chimeric antigen receptor
|
|
EP4050034B1
(en)
|
2016-09-14 |
2024-05-08 |
TeneoOne, Inc. |
Cd3 binding antibodies
|
|
WO2018060301A1
(en)
|
2016-09-30 |
2018-04-05 |
F. Hoffmann-La Roche Ag |
Bispecific antibodies against cd3
|
|
IL292551B2
(en)
|
2016-10-07 |
2023-10-01 |
Tcr2 Therapeutics Inc |
Preparations and methods for reprogramming T-cell receptors using fusion proteins
|
|
EP3535295A1
(en)
|
2016-11-02 |
2019-09-11 |
EngMab Sàrl |
Bispecific antibody against bcma and cd3 and an immunological drug for combined use in treating multiple myeloma
|
|
WO2018098365A2
(en)
|
2016-11-22 |
2018-05-31 |
TCR2 Therapeutics Inc. |
Compositions and methods for tcr reprogramming using fusion proteins
|
|
KR102633423B1
(ko)
|
2016-12-21 |
2024-02-06 |
테네오바이오, 인코포레이티드 |
항-bcma 중쇄-단독 항체
|
|
DK3561057T3
(da)
*
|
2016-12-22 |
2025-10-27 |
Daiichi Sankyo Co Ltd |
Anti-cd3-antistof og molekyle indeholdende nævnte antistof
|
|
JP7280828B2
(ja)
|
2017-01-23 |
2023-05-24 |
クレージュ メディカル カンパニー,リミテッド |
Bcmaを標的とする抗体およびその使用
|
|
US20190375815A1
(en)
|
2017-01-31 |
2019-12-12 |
Novartis Ag |
Treatment of cancer using chimeric t cell receptor proteins having multiple specificities
|
|
JP7231549B2
(ja)
*
|
2017-02-06 |
2023-03-01 |
デイナ ファーバー キャンサー インスティチュート,インコーポレイテッド |
抗体媒介性受容体シグナル伝達を増強するための組成物及び方法
|
|
KR20240023449A
(ko)
|
2017-02-08 |
2024-02-21 |
드래곤플라이 쎄라퓨틱스, 인크. |
천연 킬러 세포의 활성화를 위한 다중-특이적 결합 단백질 및 암 치료에서의 그의 치료적 용도
|
|
AU2018219348A1
(en)
*
|
2017-02-10 |
2019-08-29 |
Dragonfly Therapeutics, Inc. |
Proteins binding BCMA, NKG2D and CD16
|
|
AU2018222749B2
(en)
|
2017-02-17 |
2024-04-18 |
Fred Hutchinson Cancer Center |
Combination therapies for treatment of BCMA-related cancers and autoimmune disorders
|
|
CN108456250B
(zh)
*
|
2017-02-17 |
2025-11-28 |
恺兴生命科技(上海)有限公司 |
靶向il-13ra2的抗体及其应用
|
|
JP7685821B2
(ja)
|
2017-02-20 |
2025-05-30 |
ドラゴンフライ セラピューティクス, インコーポレイテッド |
Her2、NKG2DおよびCD16に結合するタンパク質
|
|
CN110382539B
(zh)
|
2017-02-28 |
2023-08-08 |
阿菲姆德股份有限公司 |
用于cd16a定向的nk细胞结合的串联双抗体
|
|
EP3615068A1
(en)
|
2017-04-28 |
2020-03-04 |
Novartis AG |
Bcma-targeting agent, and combination therapy with a gamma secretase inhibitor
|
|
US20200055948A1
(en)
|
2017-04-28 |
2020-02-20 |
Novartis Ag |
Cells expressing a bcma-targeting chimeric antigen receptor, and combination therapy with a gamma secretase inhibitor
|
|
US11166985B2
(en)
|
2017-05-12 |
2021-11-09 |
Crispr Therapeutics Ag |
Materials and methods for engineering cells and uses thereof in immuno-oncology
|
|
BR112019023608A2
(pt)
|
2017-05-12 |
2020-05-26 |
Crispr Therapeutics Ag |
Materiais e métodos para células manipuladas e seus usos em imuno-oncologia
|
|
EP3625253A4
(en)
|
2017-05-16 |
2021-03-24 |
Scalmibio, Inc. |
ACTIVABLE ANTIBODIES AND THEIR METHODS OF USE
|
|
CA3067584A1
(en)
|
2017-06-20 |
2018-12-27 |
Teneobio, Inc. |
Anti-bcma heavy chain-only antibodies
|
|
US11427642B2
(en)
|
2017-06-20 |
2022-08-30 |
Teneoone, Inc. |
Anti-BCMA heavy chain-only antibodies
|
|
US11053309B2
(en)
|
2017-08-04 |
2021-07-06 |
Regeneron Pharmaceuticals, Inc. |
Methods for treating active eosinophilic esophagitis
|
|
AU2018314236B2
(en)
|
2017-08-11 |
2025-02-06 |
Apterna Limited |
RNA aptamers against transferrin receptor (TfR)
|
|
WO2019035938A1
(en)
|
2017-08-16 |
2019-02-21 |
Elstar Therapeutics, Inc. |
MULTISPECIFIC MOLECULES BINDING TO BCMA AND USES THEREOF
|
|
CA3075717A1
(en)
|
2017-09-14 |
2019-03-21 |
Glaxosmithkline Intellectual Property Development Limited |
Combination treatment for cancer
|
|
CA3075714A1
(en)
|
2017-09-14 |
2019-03-21 |
Glaxosmithkline Intellectual Property Development Limited |
Combination treatment for cancer
|
|
CN111107874A
(zh)
|
2017-09-14 |
2020-05-05 |
葛兰素史密斯克莱知识产权发展有限公司 |
用于癌症的组合治疗
|
|
TWI713843B
(zh)
*
|
2017-09-30 |
2020-12-21 |
大陸商科濟生物醫藥(上海)有限公司 |
標靶bcma的抗體及其應用
|
|
CN111479925B
(zh)
|
2017-10-12 |
2024-03-08 |
麦克马斯特大学 |
具有y182t突变的t细胞-抗原偶联物及其方法和用途
|
|
KR20200086278A
(ko)
|
2017-10-18 |
2020-07-16 |
노파르티스 아게 |
선택적 단백질 분해를 위한 조성물 및 방법
|
|
JP2021502979A
(ja)
|
2017-11-15 |
2021-02-04 |
ノバルティス アーゲー |
Bcmaターゲティングキメラ抗原受容体、cd19ターゲティングキメラ抗原受容体及び併用療法
|
|
KR20200096253A
(ko)
|
2017-11-30 |
2020-08-11 |
노파르티스 아게 |
Bcma-표적화 키메라 항원 수용체, 및 이의 용도
|
|
EP3728319A1
(en)
|
2017-12-22 |
2020-10-28 |
TeneoBio, Inc. |
Heavy chain antibodies binding to cd22
|
|
KR20200104364A
(ko)
*
|
2017-12-27 |
2020-09-03 |
테네오바이오, 인코포레이티드 |
Cd3-델타/엡실론 이형이량체 특이적 항체
|
|
CN112218651A
(zh)
|
2018-01-08 |
2021-01-12 |
诺华公司 |
用于与嵌合抗原受体疗法组合的免疫增强rna
|
|
WO2019139987A1
(en)
|
2018-01-09 |
2019-07-18 |
Elstar Therapeutics, Inc. |
Calreticulin binding constructs and engineered t cells for the treatment of diseases
|
|
US20210038659A1
(en)
|
2018-01-31 |
2021-02-11 |
Novartis Ag |
Combination therapy using a chimeric antigen receptor
|
|
PT3749346T
(pt)
|
2018-02-08 |
2024-09-05 |
Dragonfly Therapeutics Inc |
Combinações de domínios variáveis de anticorpos dirigidas ao receptor nkg2d
|
|
KR20200118824A
(ko)
|
2018-02-08 |
2020-10-16 |
드래곤플라이 쎄라퓨틱스, 인크. |
자연 살해 세포를 활성화시키는 다중-특이성 결합 단백질을 수반하는 암의 병용 요법
|
|
KR20200118065A
(ko)
|
2018-02-08 |
2020-10-14 |
제넨테크, 인크. |
이중특이적 항원-결합 분자 및 이의 사용 방법
|
|
WO2019160956A1
(en)
|
2018-02-13 |
2019-08-22 |
Novartis Ag |
Chimeric antigen receptor therapy in combination with il-15r and il15
|
|
CA3091424A1
(en)
|
2018-02-20 |
2019-08-29 |
Dragonfly Therapeutics, Inc. |
Multi-specific binding proteins that bind cd33, nkg2d, and cd16, and methods of use
|
|
CN112119099A
(zh)
|
2018-03-02 |
2020-12-22 |
Cdr-生物科技股份有限公司 |
三特异性抗原结合蛋白
|
|
EP3765517A1
(en)
|
2018-03-14 |
2021-01-20 |
Elstar Therapeutics, Inc. |
Multifunctional molecules that bind to calreticulin and uses thereof
|
|
EP3774885A2
(en)
|
2018-03-30 |
2021-02-17 |
Merus N.V. |
Multivalent antibody
|
|
KR20200143436A
(ko)
|
2018-04-13 |
2020-12-23 |
아피메트 게엠베하 |
Nk 세포 결합 항체 융합 구조체
|
|
EP3784351A1
(en)
|
2018-04-27 |
2021-03-03 |
Novartis AG |
Car t cell therapies with enhanced efficacy
|
|
EP3788369A1
(en)
|
2018-05-01 |
2021-03-10 |
Novartis Ag |
Biomarkers for evaluating car-t cells to predict clinical outcome
|
|
WO2019215500A1
(en)
|
2018-05-11 |
2019-11-14 |
Crispr Therapeutics Ag |
Methods and compositions for treating cancer
|
|
JP2021523188A
(ja)
|
2018-05-13 |
2021-09-02 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッドRegeneron Pharmaceuticals, Inc. |
Il−4r阻害剤を投与することによって重度のアトピー性皮膚炎を処置するための方法
|
|
MX2020012286A
(es)
|
2018-05-16 |
2021-04-28 |
Janssen Biotech Inc |
Metodos para tratar canceres y potenciar la eficacia de agentes terapeuticos para el redireccionamiento de celulas t.
|
|
US20210213063A1
(en)
|
2018-05-25 |
2021-07-15 |
Novartis Ag |
Combination therapy with chimeric antigen receptor (car) therapies
|
|
UY38251A
(es)
*
|
2018-06-01 |
2019-12-31 |
Novartis Ag |
Moléculas de unión contra bcma y usos de las mismas
|
|
WO2019237035A1
(en)
|
2018-06-08 |
2019-12-12 |
Intellia Therapeutics, Inc. |
Compositions and methods for immunooncology
|
|
DE202019005887U1
(de)
|
2018-07-03 |
2023-06-14 |
Marengo Therapeutics, Inc. |
Anti-TCR-Antikörpermoleküle und Verwendungen davon
|
|
AR116109A1
(es)
|
2018-07-10 |
2021-03-31 |
Novartis Ag |
Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos
|
|
US11110123B2
(en)
|
2018-07-17 |
2021-09-07 |
Triumvira Immunologics Usa, Inc. |
T cell-antigen coupler with various construct optimizations
|
|
US10640562B2
(en)
|
2018-07-17 |
2020-05-05 |
Mcmaster University |
T cell-antigen coupler with various construct optimizations
|
|
SMT202400102T1
(it)
|
2018-07-19 |
2024-05-14 |
Regeneron Pharma |
Recettori chimerici dell’antigene con specificità per bcma e loro usi
|
|
TWI838389B
(zh)
|
2018-07-19 |
2024-04-11 |
美商再生元醫藥公司 |
雙特異性抗-BCMAx抗-CD3抗體及其用途
|
|
JP7439046B2
(ja)
|
2018-07-20 |
2024-02-27 |
テネオツー・インコーポレイテッド |
Cd19に結合する重鎖抗体
|
|
EA202091888A1
(ru)
|
2018-08-08 |
2020-10-23 |
Драгонфлай Терапьютикс, Инк. |
Вариабельные домены антител, нацеленные на рецептор nkg2d
|
|
EP3833392A4
(en)
|
2018-08-08 |
2022-05-18 |
Dragonfly Therapeutics, Inc. |
Multi-specific binding proteins that bind bcma, nkg2d and cd16, and methods of use
|
|
SG11202101298XA
(en)
|
2018-08-08 |
2021-03-30 |
Dragonfly Therapeutics Inc |
Proteins binding nkg2d, cd16 and a tumor-associated antigen
|
|
US20210171909A1
(en)
|
2018-08-31 |
2021-06-10 |
Novartis Ag |
Methods of making chimeric antigen receptor?expressing cells
|
|
CN112639083A
(zh)
|
2018-08-31 |
2021-04-09 |
诺华股份有限公司 |
制备表达嵌合抗原受体的细胞的方法
|
|
CN112125974B
(zh)
*
|
2018-09-25 |
2022-04-15 |
上海邦耀生物科技有限公司 |
靶向bcma蛋白的抗体、嵌合抗原受体和药物
|
|
CA3118191A1
(en)
|
2018-10-31 |
2020-05-07 |
Glaxosmithkline Intellectual Property Development Limited |
Methods of treating cancer
|
|
KR20210106521A
(ko)
*
|
2018-12-20 |
2021-08-30 |
세다르스-신나이 메디칼 센터 |
기관 이식체의 만성 항체 매개된 거부의 치료에서 클라자키주맙
|
|
AU2019402189B2
(en)
|
2018-12-20 |
2023-04-13 |
Novartis Ag |
Dosing regimen and pharmaceutical combination comprising 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives
|
|
CN109678961A
(zh)
*
|
2019-01-15 |
2019-04-26 |
深圳市南科生物工程有限公司 |
一种基于bmca纳米抗体序列的嵌合抗原受体的构建方法及其应用
|
|
CN113329792B
(zh)
|
2019-02-15 |
2024-06-28 |
诺华股份有限公司 |
取代的3-(1-氧代异吲哚啉-2-基)哌啶-2,6-二酮衍生物及其用途
|
|
BR112021015783A2
(pt)
|
2019-02-15 |
2021-10-05 |
Novartis Ag |
Derivados de 3-(1-oxo-5-(piperidin-4-il)isoindolin-2-il)piperidina-2,6-diona e usos dos mesmos
|
|
AU2020226893B2
(en)
|
2019-02-21 |
2025-02-27 |
Marengo Therapeutics, Inc. |
Multifunctional molecules that bind to T cell related cancer cells and uses thereof
|
|
SG11202108955QA
(en)
|
2019-02-21 |
2021-09-29 |
Marengo Therapeutics Inc |
Antibody molecules that bind to nkp30 and uses thereof
|
|
CA3126087A1
(en)
|
2019-02-25 |
2020-09-03 |
Novartis Ag |
Mesoporous silica particles compositions for viral delivery
|
|
CN113597328B
(zh)
|
2019-03-21 |
2025-10-31 |
瑞泽恩制药公司 |
用于治疗过敏症的il-4/il-13途径抑制剂和浆细胞消融的组合
|
|
US20230074800A1
(en)
|
2019-03-21 |
2023-03-09 |
Novartis Ag |
Car-t cell therapies with enhanced efficacy
|
|
KR20210149076A
(ko)
|
2019-04-05 |
2021-12-08 |
테네오바이오, 인코포레이티드 |
Psma에 결합하는 중쇄 항체
|
|
US20220168389A1
(en)
|
2019-04-12 |
2022-06-02 |
Novartis Ag |
Methods of making chimeric antigen receptor-expressing cells
|
|
US20220251152A1
(en)
|
2019-04-24 |
2022-08-11 |
Novartis Ag |
Compositions and methods for selective protein degradation
|
|
WO2020222176A1
(en)
|
2019-04-30 |
2020-11-05 |
Crispr Therapeutics Ag |
Allogeneic cell therapy of b cell malignancies using genetically engineered t cells targeting cd19
|
|
EA202193040A1
(ru)
*
|
2019-05-03 |
2022-03-25 |
Селджен Корпорэйшн |
Конъюгат анти-всма антитела, композиции, содержащие данный конъюгат, и способы его получения и применения
|
|
UY38701A
(es)
|
2019-05-21 |
2020-12-31 |
Novartis Ag |
Moléculas de unión a cd19, conjugados, composiciones que las comprenden y usos de las mismas
|
|
BR112021024956A2
(pt)
|
2019-06-14 |
2022-01-25 |
Teneobio Inc |
Anticorpos multiespecíficos de cadeia pesada que se ligam a cd22 e cd3
|
|
SG11202113310UA
(en)
|
2019-08-05 |
2021-12-30 |
Regeneron Pharma |
Methods for treating atopic dermatitis by administering an il-4r antagonist
|
|
EP4010001A1
(en)
|
2019-08-05 |
2022-06-15 |
Regeneron Pharmaceuticals, Inc. |
Methods for treating allergy and enhancing allergen-specific immunotherapy by administering an il-4r antagonist
|
|
US20220289859A1
(en)
|
2019-08-06 |
2022-09-15 |
Glaxosmithkline Intellectual Property Development Limited |
Biopharmacuetical Compositions and Related Methods
|
|
TW202134264A
(zh)
|
2019-11-26 |
2021-09-16 |
瑞士商諾華公司 |
嵌合抗原受體及其用途
|
|
JP7773466B2
(ja)
|
2019-11-26 |
2025-11-19 |
シャンハイ エピムアブ バイオセラピューティクス カンパニー リミテッド |
Cd3およびbcmaに対する抗体およびそれらから作製した二重特異性結合タンパク質
|
|
KR20220119430A
(ko)
*
|
2019-12-20 |
2022-08-29 |
메디뮨 엘엘씨 |
글리피칸 3을 표적으로 하는 키메라 항원 수용체로 암을 치료하는 조성물 및 방법
|
|
AU2020406350A1
(en)
|
2019-12-20 |
2022-08-11 |
Novartis Ag |
Uses of anti-TGF-beta antibodies and checkpoint inhibitors for the treatment of proliferative diseases
|
|
CN116234829A
(zh)
|
2020-01-03 |
2023-06-06 |
马伦戈治疗公司 |
抗tcr抗体分子及其用途
|
|
CN111234020B
(zh)
*
|
2020-01-23 |
2020-10-23 |
和铂医药(苏州)有限公司 |
一种bcma结合蛋白及其制备方法和应用
|
|
US11179473B2
(en)
|
2020-02-21 |
2021-11-23 |
Silverback Therapeutics, Inc. |
Nectin-4 antibody conjugates and uses thereof
|
|
US20230078007A1
(en)
*
|
2020-02-24 |
2023-03-16 |
The Regents Of The University Of California |
In-series synthetic receptor and-gate circuits for expression of a therapeutic payload by engineered cells
|
|
WO2021173985A2
(en)
|
2020-02-27 |
2021-09-02 |
Novartis Ag |
Methods of making chimeric antigen receptor-expressing cells
|
|
MX2022010685A
(es)
|
2020-02-27 |
2022-09-23 |
Novartis Ag |
Metodos de produccion de celulas que expresan receptores de antigeno quimericos.
|
|
IL297644A
(en)
|
2020-04-29 |
2022-12-01 |
Teneobio Inc |
Multispecific heavy chain antibodies with modified heavy chain constant regions
|
|
CA3214992A1
(en)
|
2020-04-29 |
2021-11-04 |
Teneobio, Inc. |
Multispecific heavy chain antibodies with modified heavy chain constant regions
|
|
CA3177024A1
(en)
|
2020-05-06 |
2021-11-11 |
Dragonfly Therapeutics, Inc. |
Proteins binding nkg2d, cd16 and clec12a
|
|
TWI894270B
(zh)
|
2020-05-11 |
2025-08-21 |
美商健生生物科技公司 |
用於治療多發性骨髓瘤之方法
|
|
CA3183905A1
(en)
|
2020-05-19 |
2021-11-25 |
Janssen Biotech, Inc |
Compositions comprising a t cell redirection therapeutic and a vla-4 adhesion pathway inhibitor
|
|
EP4165169A1
(en)
|
2020-06-11 |
2023-04-19 |
Novartis AG |
Zbtb32 inhibitors and uses thereof
|
|
BR112022025856A2
(pt)
|
2020-06-19 |
2023-01-10 |
Hoffmann La Roche |
Anticorpo que se liga a cd3 e cd19, polinucleotídeo isolado, célula hospedeira, método de produção de um anticorpo que se liga a cd3 e cd19, composição farmacêutica, uso do anticorpo, método para tratar uma doença em um indivíduo e invenção
|
|
CA3182346A1
(en)
|
2020-06-23 |
2021-12-30 |
Novartis Ag |
Dosing regimen comprising 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives
|
|
PE20230464A1
(es)
|
2020-06-30 |
2023-03-14 |
Teneobio Inc |
Union de anticuerpos multiespecificos a bcma
|
|
CN116209678A
(zh)
|
2020-07-01 |
2023-06-02 |
安尔士制药公司 |
抗asgr1抗体缀合物及其用途
|
|
JP2023536164A
(ja)
|
2020-08-03 |
2023-08-23 |
ノバルティス アーゲー |
ヘテロアリール置換3-(1-オキソイソインドリン-2-イル)ピペリジン-2,6-ジオン誘導体及びその使用
|
|
CA3188978A1
(en)
|
2020-08-21 |
2022-02-24 |
Sandeep Tharian Koshy |
Compositions and methods for in vivo generation of car expressing cells
|
|
WO2022090556A1
(en)
|
2020-11-02 |
2022-05-05 |
Hummingbird Bioscience Pte. Ltd. |
Bcma/taci antigen-binding molecules
|
|
WO2022135468A1
(zh)
*
|
2020-12-23 |
2022-06-30 |
信达生物制药(苏州)有限公司 |
抗bcma×cd3双特异性抗体及其用途
|
|
CA3210069A1
(en)
*
|
2021-03-03 |
2022-09-09 |
Tong Zhu |
Antibody-drug conjugates comprising an anti-bcma antibody
|
|
WO2022187539A1
(en)
|
2021-03-03 |
2022-09-09 |
Dragonfly Therapeutics, Inc. |
Methods of treating cancer using multi-specific binding proteins that bind nkg2d, cd16 and a tumor-associated antigen
|
|
US20240158505A1
(en)
*
|
2021-03-26 |
2024-05-16 |
Theranotics Co., Ltd. |
B7-h3 antibody or antigen-binding fragment thereof, and use thereof
|
|
TW202304979A
(zh)
|
2021-04-07 |
2023-02-01 |
瑞士商諾華公司 |
抗TGFβ抗體及其他治療劑用於治療增殖性疾病之用途
|
|
CA3214757A1
(en)
|
2021-04-08 |
2022-10-13 |
Andreas Loew |
Multifuntional molecules binding to tcr and uses thereof
|
|
AU2022267891A1
(en)
|
2021-04-27 |
2023-11-09 |
Novartis Ag |
Viral vector production system
|
|
CA3213632A1
(en)
|
2021-04-30 |
2022-11-03 |
F. Hoffmann-La Roche Ag |
Dosing for combination treatment with anti-cd20/anti-cd3 bispecific antibody and anti-cd79b antibody drug conjugate
|
|
WO2022248870A1
(en)
|
2021-05-28 |
2022-12-01 |
Glaxosmithkline Intellectual Property Development Limited |
Combination therapies for treating cancer
|
|
CA3173810A1
(en)
|
2021-06-01 |
2022-12-01 |
Andreas Bader |
Claudin 18.2 t cell-antigen couplers and uses thereof
|
|
US11453723B1
(en)
|
2021-06-25 |
2022-09-27 |
Mcmaster University |
BCMA T cell-antigen couplers and uses thereof
|
|
KR20240040786A
(ko)
|
2021-08-03 |
2024-03-28 |
글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 |
생물제약 조성물 및 안정한 동위원소 표지 펩티드 맵핑 방법
|
|
AR126838A1
(es)
|
2021-08-20 |
2023-11-22 |
Novartis Ag |
Métodos para preparar células que expresan receptores de antígeno quiméricos
|
|
US20240360216A1
(en)
*
|
2021-09-03 |
2024-10-31 |
Novoprotein Scientific Inc. |
Anti-cd3 humanized antibody
|
|
JP2024537863A
(ja)
|
2021-10-05 |
2024-10-16 |
グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッド |
がんを処置するための組合せ療法
|
|
AU2022380722A1
(en)
|
2021-11-03 |
2024-06-20 |
Janssen Biotech, Inc. |
Methods of treating cancers and enhancing efficacy of bcmaxcd3 bispecific antibodies
|
|
EP4469484A1
(en)
|
2022-01-25 |
2024-12-04 |
GlaxoSmithKline Intellectual Property Development Ltd |
Combination therapy for cancer
|
|
WO2023215725A1
(en)
|
2022-05-02 |
2023-11-09 |
Fred Hutchinson Cancer Center |
Compositions and methods for cellular immunotherapy
|
|
WO2023214325A1
(en)
|
2022-05-05 |
2023-11-09 |
Novartis Ag |
Pyrazolopyrimidine derivatives and uses thereof as tet2 inhibitors
|
|
EP4551610A1
(en)
|
2022-07-08 |
2025-05-14 |
Agency for Science, Technology and Research |
Cnx antigen-binding molecules
|
|
WO2024050524A1
(en)
|
2022-09-01 |
2024-03-07 |
University Of Georgia Research Foundation, Inc. |
Compositions and methods for directing apolipoprotein l1 to induce mammalian cell death
|
|
AU2023369684A1
(en)
|
2022-10-26 |
2025-04-17 |
Novartis Ag |
Lentiviral formulations
|
|
CN120303298A
(zh)
|
2022-12-05 |
2025-07-11 |
葛兰素史密斯克莱知识产权发展有限公司 |
使用b细胞成熟抗原拮抗剂的治疗方法
|
|
US12173081B2
(en)
|
2023-03-21 |
2024-12-24 |
Biograph 55, Inc. |
CD19/CD38 multispecific antibodies
|
|
CN120981456A
(zh)
|
2023-05-24 |
2025-11-18 |
金橘生物科技公司 |
杂环化合物及其用途
|
|
WO2025101820A1
(en)
|
2023-11-08 |
2025-05-15 |
Fred Hutchinson Cancer Center |
Compositions and methods for cellular immunotherapy
|
|
WO2025160340A2
(en)
|
2024-01-26 |
2025-07-31 |
Regeneron Pharmaceuticals, Inc. |
Combination immunosuppression for inhibiting an immune response and enabling immunogen administration and re-administration
|
|
WO2025160324A2
(en)
|
2024-01-26 |
2025-07-31 |
Regeneron Pharmaceuticals, Inc. |
Methods and compositions for using plasma cell depleting agents and/or b cell depleting agents to suppress host anti-aav antibody response and enable aav transduction and re-dosing
|
|
WO2025174963A1
(en)
|
2024-02-16 |
2025-08-21 |
Kite Pharma, Inc. |
Systems, methods, and kits for generating and administering engineered t cells and cd38 targeting compounds as a combination therapy
|
|
US20250276092A1
(en)
|
2024-03-01 |
2025-09-04 |
Regeneron Pharmaceuticals, Inc. |
Methods and compositions for re-dosing aav using anti-cd40 antagonistic antibody to suppress host anti-aav antibody response
|