|
US7608693B2
(en)
|
2006-10-02 |
2009-10-27 |
Regeneron Pharmaceuticals, Inc. |
High affinity human antibodies to human IL-4 receptor
|
|
US20130058936A1
(en)
|
2011-08-23 |
2013-03-07 |
Peter Bruenker |
Bispecific antibodies specific for t-cell activating antigens and a tumor antigen and methods of use
|
|
TWI679212B
(zh)
|
2011-11-15 |
2019-12-11 |
美商安進股份有限公司 |
針對bcma之e3以及cd3的結合分子
|
|
NZ630178A
(en)
|
2012-09-07 |
2017-06-30 |
Regeneron Pharma |
Methods for treating atopic dermatitis by administering an il-4r antagonist
|
|
MX2015003616A
(es)
|
2012-10-08 |
2015-06-05 |
Roche Glycart Ag |
Anticuerpos sin fc que comprenden dos fragmentos fab y metodos de uso.
|
|
EP2953974B1
(en)
|
2013-02-05 |
2017-12-20 |
EngMab Sàrl |
Bispecific antibodies against cd3epsilon and bcma
|
|
PT2961771T
(pt)
|
2013-02-26 |
2020-02-28 |
Roche Glycart Ag |
Moléculas de ligação ao antigénio biespecíficas para ativação das células t, específicas para cd3 e cea
|
|
TWI755763B
(zh)
|
2013-06-04 |
2022-02-21 |
美商再生元醫藥公司 |
藉由投與il-4r抑制劑以治療過敏及增強過敏原-特異之免疫療法的方法
|
|
TWI682781B
(zh)
|
2013-07-11 |
2020-01-21 |
美商再生元醫藥公司 |
藉由投與il-4r抑制劑治療嗜酸性食道炎的方法
|
|
GB201317928D0
(en)
*
|
2013-10-10 |
2013-11-27 |
Ucl Business Plc |
Molecule
|
|
KR102480433B1
(ko)
*
|
2014-02-07 |
2022-12-21 |
맥마스터 유니버시티 |
3기능성 t 세포-항원 커플러 및 이의 제조 방법 및 용도
|
|
KR20160120735A
(ko)
|
2014-02-28 |
2016-10-18 |
리제너론 파아마슈티컬스, 인크. |
Il-4r 길항제의 투여에 의한 피부 감염의 치료 방법
|
|
CR20170032A
(es)
|
2014-08-04 |
2017-04-04 |
Hoffmann La Roche |
Moleculas biespecíficas de unión a antígeno activadoras de células t
|
|
ES2850325T3
(es)
|
2014-10-09 |
2021-08-27 |
Engmab Sarl |
Anticuerpos biespecíficos contra CD3epsilon y ROR1
|
|
EP3023437A1
(en)
*
|
2014-11-20 |
2016-05-25 |
EngMab AG |
Bispecific antibodies against CD3epsilon and BCMA
|
|
PL3221357T3
(pl)
|
2014-11-20 |
2020-11-02 |
F. Hoffmann-La Roche Ag |
Wspólne łańcuchy lekkie i sposoby zastosowania
|
|
HRP20240959T1
(hr)
|
2014-11-20 |
2024-10-25 |
F. Hoffmann - La Roche Ag |
Kombinirana terapija bispecifičnom antigen vezujućom molekulom koja aktivira t stanice i antagonistom vezivanja osi pd-1
|
|
MX2017006571A
(es)
|
2014-11-20 |
2017-09-29 |
Hoffmann La Roche |
Moleculas de union a antigeno biespecificas activadoras de celulas t.
|
|
EP3029068A1
(en)
*
|
2014-12-03 |
2016-06-08 |
EngMab AG |
Bispecific antibodies against CD3epsilon and BCMA for use in the treatment of diseases
|
|
TWI703159B
(zh)
|
2015-04-13 |
2020-09-01 |
美商輝瑞股份有限公司 |
Bcma特異性治療性抗體及其用途
|
|
SG11201707089WA
(en)
|
2015-04-13 |
2017-10-30 |
Pfizer |
Chimeric antigen receptors targeting b-cell maturation antigen
|
|
DK3298033T4
(da)
|
2015-05-18 |
2023-10-02 |
Tcr2 Therapeutics Inc |
Sammensætninger og medicinske anvendelser til tcr-reprogrammering under anvendelse af fusionsproteiner
|
|
TWI796283B
(zh)
|
2015-07-31 |
2023-03-21 |
德商安美基研究(慕尼黑)公司 |
Msln及cd3抗體構築體
|
|
EA039859B1
(ru)
|
2015-07-31 |
2022-03-21 |
Эмджен Рисерч (Мюник) Гмбх |
Биспецифические конструкты антител, связывающие egfrviii и cd3
|
|
TWI829617B
(zh)
|
2015-07-31 |
2024-01-21 |
德商安美基研究(慕尼黑)公司 |
Flt3及cd3抗體構築體
|
|
TWI744242B
(zh)
|
2015-07-31 |
2021-11-01 |
德商安美基研究(慕尼黑)公司 |
Egfrviii及cd3抗體構築體
|
|
HRP20200390T1
(hr)
*
|
2015-08-03 |
2020-06-12 |
Engmab Sàrl |
Monoklonska antitijela protiv humanog antigena starenja b stanica (bcma)
|
|
CN105384825B
(zh)
|
2015-08-11 |
2018-06-01 |
南京传奇生物科技有限公司 |
一种基于单域抗体的双特异性嵌合抗原受体及其应用
|
|
UA127515C2
(uk)
|
2015-08-17 |
2023-09-20 |
Янссен Байотек, Інк. |
Антитіло до всма, біспецифічна антигензв'язувальна молекула, що зв'язує всма і cd3, і їх використання
|
|
AR106188A1
(es)
|
2015-10-01 |
2017-12-20 |
Hoffmann La Roche |
Anticuerpos anti-cd19 humano humanizados y métodos de utilización
|
|
MA43025A
(fr)
|
2015-10-02 |
2021-05-26 |
Hoffmann La Roche |
Molécules bispécifiques de liaison à l'antigène activant les lymphocytes t anti-ceaxcd3
|
|
EP4026848A1
(en)
|
2015-12-09 |
2022-07-13 |
F. Hoffmann-La Roche AG |
Type ii anti-cd20 antibody for reducing the cytokine release syndrome
|
|
AU2017205089B2
(en)
|
2016-01-08 |
2023-10-05 |
F. Hoffmann-La Roche Ag |
Methods of treating CEA-positive cancers using PD-1 axis binding antagonists and anti-CEA/anti-CD3 bispecific antibodies
|
|
UA126657C2
(uk)
*
|
2016-02-03 |
2023-01-11 |
Емджен Рісерч (Мюнік) Ґмбг |
ОДНОЛАНЦЮГОВА КОНСТРУКЦІЯ АНТИТІЛА ДО BCMA І CD3<font face="Symbol">e</font>
|
|
HUE060504T2
(hu)
|
2016-02-03 |
2023-03-28 |
Amgen Res Munich Gmbh |
PSMA és CD3 bispecifikus T-sejthez kötõ ellenanyag-konstrukciók
|
|
CN116063503A
(zh)
*
|
2016-02-17 |
2023-05-05 |
思进股份有限公司 |
Bcma抗体和其用以治疗癌症和免疫病症的用途
|
|
KR20180118175A
(ko)
|
2016-03-04 |
2018-10-30 |
노파르티스 아게 |
다중 키메라 항원 수용체 (car) 분자를 발현하는 세포 및 그에 따른 용도
|
|
MX2018011542A
(es)
|
2016-03-22 |
2019-02-07 |
Hoffmann La Roche |
Moleculas biespecificas de celulas t activadas por proteasas.
|
|
AR108067A1
(es)
*
|
2016-04-01 |
2018-07-11 |
Kite Pharma Inc |
Moléculas de unión y métodos de uso de los mismos
|
|
CN109328074A
(zh)
|
2016-04-01 |
2019-02-12 |
凯德药业股份有限公司 |
嵌合抗原和t细胞受体及使用的方法
|
|
CA3177398A1
(en)
|
2016-04-01 |
2017-10-05 |
Kite Pharma, Inc. |
Chimeric receptors and methods of use thereof
|
|
PL3443096T3
(pl)
|
2016-04-15 |
2023-06-19 |
Novartis Ag |
Kompozycje i sposoby do selektywnej ekspresji chimerycznych receptorów antygenowych
|
|
WO2017223111A1
(en)
|
2016-06-21 |
2017-12-28 |
Teneobio, Inc. |
Cd3 binding antibodies
|
|
JP2019527696A
(ja)
|
2016-08-01 |
2019-10-03 |
ノバルティス アーゲー |
プロm2マクロファージ分子の阻害剤と組み合わせてキメラ抗原受容体を用いる癌の処置
|
|
JP7109789B2
(ja)
|
2016-08-02 |
2022-08-01 |
ティーシーアール2 セラピューティクス インク. |
融合タンパク質を使用したtcrの再プログラム化のための組成物及び方法
|
|
US11771743B2
(en)
|
2016-09-01 |
2023-10-03 |
Regeneron Pharmaceuticals, Inc. |
Methods for preventing or treating allergy by administering an IL-4R antagonist
|
|
US20180064758A1
(en)
*
|
2016-09-05 |
2018-03-08 |
Ucl Business Plc |
Chimeric antigen receptor
|
|
MY200988A
(en)
*
|
2016-09-14 |
2024-01-27 |
Teneobio Inc |
CD3 Binding Antibodies
|
|
PL3519437T3
(pl)
|
2016-09-30 |
2022-01-17 |
F. Hoffmann-La Roche Ag |
Przeciwciała dwuswoiste przeciwko p95HER2
|
|
CA3036745A1
(en)
|
2016-10-07 |
2018-04-12 |
TCR2 Therapeutics Inc. |
Compositions and methods for t-cell receptors reprogramming using fusion proteins
|
|
IL266424B2
(en)
*
|
2016-11-02 |
2023-09-01 |
Engmab Sarl |
A bispecific antibody against bcma and cd3 and an immunological drug for combined treatment in multiple myeloma
|
|
CA3044593A1
(en)
|
2016-11-22 |
2018-05-31 |
TCR2 Therapeutics Inc. |
Compositions and methods for tcr reprogramming using fusion proteins
|
|
EP3559035A1
(en)
|
2016-12-21 |
2019-10-30 |
TeneoBio, Inc. |
Anti-bcma heavy chain-only antibodies
|
|
ES3039621T3
(en)
*
|
2016-12-22 |
2025-10-23 |
Daiichi Sankyo Co Ltd |
Anti-cd3 antibody, and molecule containing said antibody
|
|
CN108341872B
(zh)
*
|
2017-01-23 |
2020-05-19 |
科济生物医药(上海)有限公司 |
靶向bcma的抗体及其应用
|
|
WO2018144535A1
(en)
|
2017-01-31 |
2018-08-09 |
Novartis Ag |
Treatment of cancer using chimeric t cell receptor proteins having multiple specificities
|
|
JP7231549B2
(ja)
*
|
2017-02-06 |
2023-03-01 |
デイナ ファーバー キャンサー インスティチュート,インコーポレイテッド |
抗体媒介性受容体シグナル伝達を増強するための組成物及び方法
|
|
JP2020506971A
(ja)
|
2017-02-08 |
2020-03-05 |
ドラゴンフライ セラピューティクス, インコーポレイテッド |
ナチュラルキラー細胞の活性化のための多重特異性結合タンパク質およびがんを処置するためのその治療的使用
|
|
MY205850A
(en)
*
|
2017-02-10 |
2024-11-15 |
Dragonfly Therapeutics Inc |
Proteins binding bcma, nkg2d and cd16
|
|
CN108456250B
(zh)
*
|
2017-02-17 |
2025-11-28 |
恺兴生命科技(上海)有限公司 |
靶向il-13ra2的抗体及其应用
|
|
WO2018151836A1
(en)
|
2017-02-17 |
2018-08-23 |
Fred Hutchinson Cancer Research Center |
Combination therapies for treatment of bcma-related cancers and autoimmune disorders
|
|
SG11201907646YA
(en)
|
2017-02-20 |
2019-09-27 |
Dragonfly Therapeutics Inc |
Proteins binding her2, nkg2d and cd16
|
|
EP3589655B1
(en)
|
2017-02-28 |
2022-10-26 |
Affimed GmbH |
Tandem-diabody for cd16a-directed nk-cell engagement
|
|
EP3615055A1
(en)
|
2017-04-28 |
2020-03-04 |
Novartis AG |
Cells expressing a bcma-targeting chimeric antigen receptor, and combination therapy with a gamma secretase inhibitor
|
|
US20200179511A1
(en)
|
2017-04-28 |
2020-06-11 |
Novartis Ag |
Bcma-targeting agent, and combination therapy with a gamma secretase inhibitor
|
|
US11166985B2
(en)
|
2017-05-12 |
2021-11-09 |
Crispr Therapeutics Ag |
Materials and methods for engineering cells and uses thereof in immuno-oncology
|
|
EP3621981A2
(en)
|
2017-05-12 |
2020-03-18 |
CRISPR Therapeutics AG |
Materials and methods for engineering cells and uses thereof in immuno-oncology
|
|
EP3625253A4
(en)
|
2017-05-16 |
2021-03-24 |
Scalmibio, Inc. |
ACTIVABLE ANTIBODIES AND THEIR METHODS OF USE
|
|
CN118146370A
(zh)
|
2017-06-20 |
2024-06-07 |
特纳奥尼股份有限公司 |
仅有重链的抗bcma抗体
|
|
CA3067584A1
(en)
|
2017-06-20 |
2018-12-27 |
Teneobio, Inc. |
Anti-bcma heavy chain-only antibodies
|
|
WO2019028367A1
(en)
|
2017-08-04 |
2019-02-07 |
Regeneron Pharmaceuticals, Inc. |
METHODS OF TREATING ESOPHAGITIS WITH ACTIVE EOSINOPHILES
|
|
CN111542326B
(zh)
|
2017-08-11 |
2024-06-04 |
希望之城 |
转铁蛋白受体(TfR)的RNA适体
|
|
WO2019035938A1
(en)
|
2017-08-16 |
2019-02-21 |
Elstar Therapeutics, Inc. |
MULTISPECIFIC MOLECULES BINDING TO BCMA AND USES THEREOF
|
|
US20200254093A1
(en)
|
2017-09-14 |
2020-08-13 |
Glaxosmithkline Intellectual Property Development Limited |
Combination treatment for cancer
|
|
BR112020005079A2
(pt)
|
2017-09-14 |
2020-09-15 |
Glaxosmithkline Intellectual Property Development Limited |
tratamento de combinação para câncer
|
|
EP3692066A2
(en)
|
2017-09-14 |
2020-08-12 |
GlaxoSmithKline Intellectual Property Development Limited |
Combination treatment for cancer
|
|
TWI713843B
(zh)
*
|
2017-09-30 |
2020-12-21 |
大陸商科濟生物醫藥(上海)有限公司 |
標靶bcma的抗體及其應用
|
|
WO2019071358A1
(en)
|
2017-10-12 |
2019-04-18 |
Mcmaster University |
Y182T MUTATION T CELL ANTIGEN COUPLEUR AND METHODS AND USES THEREOF
|
|
IL321733A
(en)
|
2017-10-18 |
2025-08-01 |
Novartis Ag |
Compositions and methods for selective degradation of proteins
|
|
EP3710040A1
(en)
|
2017-11-15 |
2020-09-23 |
Novartis AG |
Bcma-targeting chimeric antigen receptor, cd19-targeting chimeric antigen receptor, and combination therapies
|
|
JP2021509009A
(ja)
|
2017-11-30 |
2021-03-18 |
ノバルティス アーゲー |
Bcmaターゲティングキメラ抗原受容体及びその使用
|
|
WO2019126756A1
(en)
|
2017-12-22 |
2019-06-27 |
Teneobio, Inc. |
Heavy chain antibodies binding to cd22
|
|
US20200339685A1
(en)
*
|
2017-12-27 |
2020-10-29 |
Teneobio, Inc. |
Cd3-delta/epsilon heterodimer specific antibodies
|
|
US20200368268A1
(en)
|
2018-01-08 |
2020-11-26 |
Novartis Ag |
Immune-enhancing rnas for combination with chimeric antigen receptor therapy
|
|
WO2019139987A1
(en)
|
2018-01-09 |
2019-07-18 |
Elstar Therapeutics, Inc. |
Calreticulin binding constructs and engineered t cells for the treatment of diseases
|
|
US20210038659A1
(en)
|
2018-01-31 |
2021-02-11 |
Novartis Ag |
Combination therapy using a chimeric antigen receptor
|
|
PE20210375A1
(es)
|
2018-02-08 |
2021-03-02 |
Dragonfly Therapeutics Inc |
Terapia de combinacion del cancer que incluye proteinas de union multiespecificas que activan a las celulas asesinas naturales
|
|
FI3749346T3
(fi)
|
2018-02-08 |
2024-09-04 |
Dragonfly Therapeutics Inc |
Nkg2d-reseptoriin kohdistuvat vasta-aineen vaihtelevan domeenin yhdistelmät
|
|
AR115360A1
(es)
|
2018-02-08 |
2021-01-13 |
Genentech Inc |
Moléculas de unión al antígeno y métodos de uso
|
|
EP3752203A1
(en)
|
2018-02-13 |
2020-12-23 |
Novartis AG |
Chimeric antigen receptor therapy in combination with il-15r and il15
|
|
MX2020008684A
(es)
|
2018-02-20 |
2020-12-07 |
Dragonfly Therapeutics Inc |
Proteinas de union multiespecificas que se unen a cd33, nkg2d y cd16 y metodos de uso.
|
|
AU2019228128A1
(en)
|
2018-03-02 |
2020-09-03 |
Cdr-Life Ag |
Trispecific antigen binding proteins
|
|
US12152073B2
(en)
|
2018-03-14 |
2024-11-26 |
Marengo Therapeutics, Inc. |
Multifunctional molecules that bind to calreticulin and uses thereof
|
|
JP7603578B2
(ja)
|
2018-03-30 |
2024-12-20 |
メルス ナムローゼ フェンノートシャップ |
多価抗体
|
|
PH12020551664B1
(en)
|
2018-04-13 |
2023-05-19 |
Affimed Gmbh |
Nk cell engaging antibody fusion constructs
|
|
WO2019210153A1
(en)
|
2018-04-27 |
2019-10-31 |
Novartis Ag |
Car t cell therapies with enhanced efficacy
|
|
WO2019213282A1
(en)
|
2018-05-01 |
2019-11-07 |
Novartis Ag |
Biomarkers for evaluating car-t cells to predict clinical outcome
|
|
CN112105420A
(zh)
|
2018-05-11 |
2020-12-18 |
克里斯珀医疗股份公司 |
用于治疗癌症的方法和组合物
|
|
CN120227453A
(zh)
|
2018-05-13 |
2025-07-01 |
瑞泽恩制药公司 |
用于通过施用il-4r抑制剂治疗特应性皮炎的方法
|
|
MX2020012286A
(es)
|
2018-05-16 |
2021-04-28 |
Janssen Biotech Inc |
Metodos para tratar canceres y potenciar la eficacia de agentes terapeuticos para el redireccionamiento de celulas t.
|
|
WO2019227003A1
(en)
|
2018-05-25 |
2019-11-28 |
Novartis Ag |
Combination therapy with chimeric antigen receptor (car) therapies
|
|
EP3802611A2
(en)
*
|
2018-06-01 |
2021-04-14 |
Novartis AG |
Binding molecules against bcma and uses thereof
|
|
EP3802825A1
(en)
|
2018-06-08 |
2021-04-14 |
Intellia Therapeutics, Inc. |
Compositions and methods for immunooncology
|
|
CN112955465A
(zh)
|
2018-07-03 |
2021-06-11 |
马伦戈治疗公司 |
抗tcr抗体分子及其用途
|
|
AR116109A1
(es)
|
2018-07-10 |
2021-03-31 |
Novartis Ag |
Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos
|
|
US11110123B2
(en)
|
2018-07-17 |
2021-09-07 |
Triumvira Immunologics Usa, Inc. |
T cell-antigen coupler with various construct optimizations
|
|
US10640562B2
(en)
|
2018-07-17 |
2020-05-05 |
Mcmaster University |
T cell-antigen coupler with various construct optimizations
|
|
SMT202400102T1
(it)
|
2018-07-19 |
2024-05-14 |
Regeneron Pharma |
Recettori chimerici dell’antigene con specificità per bcma e loro usi
|
|
TWI838389B
(zh)
|
2018-07-19 |
2024-04-11 |
美商再生元醫藥公司 |
雙特異性抗-BCMAx抗-CD3抗體及其用途
|
|
CN116769032A
(zh)
|
2018-07-20 |
2023-09-19 |
坦尼奥第二公司 |
与cd19结合的重链抗体
|
|
JP7482363B2
(ja)
|
2018-08-08 |
2024-05-14 |
ドラゴンフライ セラピューティクス, インコーポレイテッド |
Nkg2d、cd16及び腫瘍関連抗原に結合するタンパク質
|
|
EA202091888A1
(ru)
|
2018-08-08 |
2020-10-23 |
Драгонфлай Терапьютикс, Инк. |
Вариабельные домены антител, нацеленные на рецептор nkg2d
|
|
US12384851B2
(en)
|
2018-08-08 |
2025-08-12 |
Dragonfly Therapeutics, Inc. |
Multi-specific binding proteins that bind BCMA, NKG2D and CD16, and methods of use
|
|
EP3844265A2
(en)
|
2018-08-31 |
2021-07-07 |
Novartis AG |
Methods of making chimeric antigen receptor-expressing cells
|
|
EP3844267B1
(en)
|
2018-08-31 |
2025-06-25 |
Novartis AG |
Methods of making chimeric antigen receptor-expressing cells
|
|
CN112125974B
(zh)
*
|
2018-09-25 |
2022-04-15 |
上海邦耀生物科技有限公司 |
靶向bcma蛋白的抗体、嵌合抗原受体和药物
|
|
WO2020089794A1
(en)
|
2018-10-31 |
2020-05-07 |
Glaxosmithkline Intellectual Property Development Limited |
Methods of treating cancer
|
|
US20240245670A1
(en)
|
2018-12-20 |
2024-07-25 |
Novartis Ag |
Dosing regimen and pharmaceutical combination comprising 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives
|
|
EP3897718A4
(en)
*
|
2018-12-20 |
2022-09-14 |
Cedars-Sinai Medical Center |
CLAZAKIZUMAB FOR THE TREATMENT OF CHRONIC ANTIBODY-MEDIATED REJECTION OF ORGAN TRANSPLANT
|
|
CN109678961A
(zh)
*
|
2019-01-15 |
2019-04-26 |
深圳市南科生物工程有限公司 |
一种基于bmca纳米抗体序列的嵌合抗原受体的构建方法及其应用
|
|
EP3924055B1
(en)
|
2019-02-15 |
2024-04-03 |
Novartis AG |
Substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
EP3924054B1
(en)
|
2019-02-15 |
2025-04-02 |
Novartis AG |
3-(1-oxo-5-(piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
WO2020172605A1
(en)
|
2019-02-21 |
2020-08-27 |
Elstar Therapeutics, Inc. |
Antibody molecules that bind to nkp30 and uses thereof
|
|
JP7710373B2
(ja)
|
2019-02-21 |
2025-07-18 |
マレンゴ・セラピューティクス,インコーポレーテッド |
T細胞関連のがん細胞に結合する多機能性分子およびその使用
|
|
WO2020176397A1
(en)
|
2019-02-25 |
2020-09-03 |
Novartis Ag |
Mesoporous silica particles compositions for viral delivery
|
|
KR20210143246A
(ko)
*
|
2019-03-21 |
2021-11-26 |
리제너론 파아마슈티컬스, 인크. |
알레르기 치료용 il-4/il-13 경로 억제제 및 형질 세포 절제의 병용
|
|
US20230074800A1
(en)
|
2019-03-21 |
2023-03-09 |
Novartis Ag |
Car-t cell therapies with enhanced efficacy
|
|
EA202192736A1
(ru)
|
2019-04-05 |
2022-01-27 |
Тенеобио, Инк. |
Антитела, содержащие только тяжелые цепи, которые связываются с псма
|
|
US20220168389A1
(en)
|
2019-04-12 |
2022-06-02 |
Novartis Ag |
Methods of making chimeric antigen receptor-expressing cells
|
|
US20220251152A1
(en)
|
2019-04-24 |
2022-08-11 |
Novartis Ag |
Compositions and methods for selective protein degradation
|
|
WO2020222176A1
(en)
|
2019-04-30 |
2020-11-05 |
Crispr Therapeutics Ag |
Allogeneic cell therapy of b cell malignancies using genetically engineered t cells targeting cd19
|
|
BR112021021728A2
(pt)
*
|
2019-05-03 |
2021-12-28 |
Celgene Corp |
Conjugado de anticorpo anti-bcma, composições que compreendem os mesmos e métodos para fazer e usar os mesmos
|
|
CU20210096A7
(es)
|
2019-05-21 |
2022-06-06 |
Novartis Ag |
Moléculas de unión a cd19
|
|
PH12021553145A1
(en)
|
2019-06-14 |
2022-07-25 |
Teneobio Inc |
Multispecific heavy chain antibodies binding to cd22 and cd3
|
|
KR20220042217A
(ko)
|
2019-08-05 |
2022-04-04 |
리제너론 파아마슈티컬스, 인크. |
Il-4r 길항제를 투여함에 의해 알레르기를 치료하고 알레르겐-특이적 면역치료요법을 증진시키기 위한 방법
|
|
EP4010373A1
(en)
|
2019-08-05 |
2022-06-15 |
Regeneron Pharmaceuticals, Inc. |
Methods for treating atopic dermatitis by administering an il-4r antagonist
|
|
MX2022001626A
(es)
|
2019-08-06 |
2022-03-02 |
Glaxosmithkline Ip Dev Ltd |
Composiciones biofarmaceuticas y procedimientos conexos.
|
|
IL316618A
(en)
*
|
2019-11-26 |
2024-12-01 |
Shanghai Epimab Biotherapeutics Co Ltd |
Antibodies to CD3 and BCMA and bispecific binding proteins produced from them
|
|
PH12022551291A1
(en)
|
2019-11-26 |
2023-11-20 |
Novartis Ag |
Chimeric antigen receptors binding bcma and cd19 and uses thereof
|
|
KR20220119430A
(ko)
*
|
2019-12-20 |
2022-08-29 |
메디뮨 엘엘씨 |
글리피칸 3을 표적으로 하는 키메라 항원 수용체로 암을 치료하는 조성물 및 방법
|
|
KR20220116522A
(ko)
|
2019-12-20 |
2022-08-23 |
노파르티스 아게 |
증식성 질환의 치료를 위한 항-tgf-베타 항체 및 체크포인트 억제제의 용도
|
|
CA3166629A1
(en)
|
2020-01-03 |
2021-07-08 |
Marengo Therapeutics, Inc. |
Anti-tcr antibody molecules and uses thereof
|
|
CN111234020B
(zh)
*
|
2020-01-23 |
2020-10-23 |
和铂医药(苏州)有限公司 |
一种bcma结合蛋白及其制备方法和应用
|
|
WO2021168274A1
(en)
|
2020-02-21 |
2021-08-26 |
Silverback Therapeutics, Inc. |
Nectin-4 antibody conjugates and uses thereof
|
|
US20230078007A1
(en)
*
|
2020-02-24 |
2023-03-16 |
The Regents Of The University Of California |
In-series synthetic receptor and-gate circuits for expression of a therapeutic payload by engineered cells
|
|
CN115397460A
(zh)
|
2020-02-27 |
2022-11-25 |
诺华股份有限公司 |
制备表达嵌合抗原受体的细胞的方法
|
|
BR112022017148A2
(pt)
|
2020-02-27 |
2022-11-08 |
Novartis Ag |
Métodos para produzir células que expressam receptor de antígeno quimérico
|
|
CA3214992A1
(en)
|
2020-04-29 |
2021-11-04 |
Teneobio, Inc. |
Multispecific heavy chain antibodies with modified heavy chain constant regions
|
|
KR20250007022A
(ko)
|
2020-04-29 |
2025-01-13 |
테네오원, 인코포레이티드 |
변형된 중쇄 불변 영역을 갖는 다중특이적 중쇄 항체
|
|
TW202208428A
(zh)
|
2020-05-06 |
2022-03-01 |
美商蜻蜓醫療公司 |
結合nkg2d、cd16及clec12a之蛋白質
|
|
AU2021272291A1
(en)
|
2020-05-11 |
2023-02-02 |
Janssen Biotech, Inc. |
Methods for treating multiple myeloma
|
|
KR20230013258A
(ko)
|
2020-05-19 |
2023-01-26 |
얀센 바이오테크 인코포레이티드 |
T 세포 재유도 치료제 및 vla-4 부착 경로 억제제를 포함하는 조성물
|
|
CA3185455A1
(en)
|
2020-06-11 |
2021-12-16 |
Novartis Ag |
Zbtb32 inhibitors and uses thereof
|
|
TW202519548A
(zh)
|
2020-06-19 |
2025-05-16 |
瑞士商赫孚孟拉羅股份公司 |
與 cd3 及 cd19 結合之抗體
|
|
CA3182346A1
(en)
|
2020-06-23 |
2021-12-30 |
Novartis Ag |
Dosing regimen comprising 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives
|
|
PE20230464A1
(es)
|
2020-06-30 |
2023-03-14 |
Teneobio Inc |
Union de anticuerpos multiespecificos a bcma
|
|
TW202216211A
(zh)
|
2020-07-01 |
2022-05-01 |
美商希沃爾拜克治療公司 |
抗asgr1抗體共軛物及其用途
|
|
CN116134027B
(zh)
|
2020-08-03 |
2025-01-24 |
诺华股份有限公司 |
杂芳基取代的3-(1-氧代异吲哚啉-2-基)哌啶-2,6-二酮衍生物及其用途
|
|
AU2021329404A1
(en)
|
2020-08-21 |
2023-04-20 |
Novartis Ag |
Compositions and methods for in vivo generation of car expressing cells
|
|
US20230374147A1
(en)
|
2020-11-02 |
2023-11-23 |
Hummingbird Bioscience Pte. Ltd. |
Bcma/taci antigen-binding molecules
|
|
WO2022135468A1
(zh)
*
|
2020-12-23 |
2022-06-30 |
信达生物制药(苏州)有限公司 |
抗bcma×cd3双特异性抗体及其用途
|
|
US20240181073A1
(en)
*
|
2021-03-03 |
2024-06-06 |
Sorrento Therapeutics, Inc. |
Antibody-Drug Conjugates Comprising an Anti-BCMA Antibody
|
|
EP4301774A4
(en)
|
2021-03-03 |
2025-08-13 |
Dragonfly Therapeutics Inc |
METHODS OF TREATING CANCER USING MULTI-SPECIFIC BINDING PROTEINS THAT BIND TO NKG2D, CD16, AND A TUMOR-ASSOCIATED ANTIGEN
|
|
US20240158505A1
(en)
*
|
2021-03-26 |
2024-05-16 |
Theranotics Co., Ltd. |
B7-h3 antibody or antigen-binding fragment thereof, and use thereof
|
|
TW202304979A
(zh)
|
2021-04-07 |
2023-02-01 |
瑞士商諾華公司 |
抗TGFβ抗體及其他治療劑用於治療增殖性疾病之用途
|
|
US20250099579A1
(en)
|
2021-04-08 |
2025-03-27 |
Marengo Therapeutics, Inc. |
Multispecific molecules binding to tcr and uses thereof
|
|
AU2022267891A1
(en)
|
2021-04-27 |
2023-11-09 |
Novartis Ag |
Viral vector production system
|
|
CA3213632A1
(en)
|
2021-04-30 |
2022-11-03 |
F. Hoffmann-La Roche Ag |
Dosing for combination treatment with anti-cd20/anti-cd3 bispecific antibody and anti-cd79b antibody drug conjugate
|
|
WO2022248870A1
(en)
|
2021-05-28 |
2022-12-01 |
Glaxosmithkline Intellectual Property Development Limited |
Combination therapies for treating cancer
|
|
CA3173810A1
(en)
|
2021-06-01 |
2022-12-01 |
Andreas Bader |
Claudin 18.2 t cell-antigen couplers and uses thereof
|
|
US11453723B1
(en)
|
2021-06-25 |
2022-09-27 |
Mcmaster University |
BCMA T cell-antigen couplers and uses thereof
|
|
CA3227515A1
(en)
|
2021-08-03 |
2023-02-09 |
Glaxosmithkline Intellectual Property Development Limited |
Biopharmaceutical compositions and stable isotope labeling peptide mapping method
|
|
US20250000973A1
(en)
|
2021-08-20 |
2025-01-02 |
Novartis Ag |
Methods of making chimeric antigen receptor-expressing cells
|
|
JP2024532500A
(ja)
*
|
2021-09-03 |
2024-09-05 |
蘇州近岸蛋白質科技股▲ふん▼有限公司 |
抗cd3ヒト化抗体
|
|
EP4412713A1
(en)
|
2021-10-05 |
2024-08-14 |
GlaxoSmithKline Intellectual Property Development Ltd |
Combination therapies for treating cancer
|
|
CA3237357A1
(en)
|
2021-11-03 |
2023-05-11 |
Janssen Biotech, Inc. |
Methods of treating cancers and enhancing efficacy of bcmaxcd3 bispecific antibodies
|
|
CN118591560A
(zh)
|
2022-01-25 |
2024-09-03 |
葛兰素史密斯克莱知识产权发展有限公司 |
癌症的组合疗法
|
|
WO2023215725A1
(en)
|
2022-05-02 |
2023-11-09 |
Fred Hutchinson Cancer Center |
Compositions and methods for cellular immunotherapy
|
|
WO2023214325A1
(en)
|
2022-05-05 |
2023-11-09 |
Novartis Ag |
Pyrazolopyrimidine derivatives and uses thereof as tet2 inhibitors
|
|
CN120092020A
(zh)
|
2022-07-08 |
2025-06-03 |
新加坡科技研究局 |
Cnx抗原结合分子
|
|
EP4581052A1
(en)
|
2022-09-01 |
2025-07-09 |
University of Georgia Research Foundation, Inc. |
Compositions and methods for directing apolipoprotein l1 to induce mammalian cell death
|
|
WO2024089639A1
(en)
|
2022-10-26 |
2024-05-02 |
Novartis Ag |
Lentiviral formulations
|
|
EP4630454A1
(en)
|
2022-12-05 |
2025-10-15 |
GlaxoSmithKline Intellectual Property Development Ltd |
Methods of treatment using b-cell maturation antigen antagonists
|
|
US12173081B2
(en)
|
2023-03-21 |
2024-12-24 |
Biograph 55, Inc. |
CD19/CD38 multispecific antibodies
|
|
AU2024276994A1
(en)
|
2023-05-24 |
2025-10-23 |
Kumquat Biosciences Inc. |
Heterocyclic compounds and uses thereof
|
|
WO2025101820A1
(en)
|
2023-11-08 |
2025-05-15 |
Fred Hutchinson Cancer Center |
Compositions and methods for cellular immunotherapy
|
|
US20250242018A1
(en)
|
2024-01-26 |
2025-07-31 |
Regeneron Pharmaceuticals, Inc. |
Combination immunosuppression for inhibiting an immune response and enabling immunogen administration and re-administration
|
|
US20250242056A1
(en)
|
2024-01-26 |
2025-07-31 |
Regeneron Pharmaceuticals, Inc. |
Methods and compositions for using plasma cell depleting agents and/or b cell depleting agents to suppress host anti-aav antibody response and enable aav transduction and re-dosing
|
|
WO2025174963A1
(en)
|
2024-02-16 |
2025-08-21 |
Kite Pharma, Inc. |
Systems, methods, and kits for generating and administering engineered t cells and cd38 targeting compounds as a combination therapy
|
|
WO2025184567A1
(en)
|
2024-03-01 |
2025-09-04 |
Regeneron Pharmaceuticals, Inc. |
Methods and compositions for re-dosing aav using anti-cd40 antagonistic antibody to suppress host anti-aav antibody response
|